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Wyświetlanie 1-20 z 47
Tytuł:
Comparative overall survival of CDK4/6 inhibitors in combination with endocrine therapy in advanced breast cancer.
Autorzy:
Kappel C; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Elliott MJ; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Kumar V; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Nadler MB; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Desnoyers A; Hôpital Charles-Lemoyne, Greenfield Park, QC, Canada.
Amir E; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada. eitan.amir@uhn.ca.; Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada. eitan.amir@uhn.ca.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3129. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols*/adverse effects
Breast Neoplasms*/drug therapy
Female ; Humans ; Aminopyridines ; Benzimidazoles ; Cyclin-Dependent Kinase 4 ; Cyclin-Dependent Kinase 6 ; Cyclin-Dependent Kinase Inhibitor Proteins ; Neutropenia/chemically induced ; Purines ; Clinical Trials, Phase III as Topic ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Magnitude of effect and sample size justification in trials supporting anti-cancer drug approval by the US Food and Drug Administration.
Autorzy:
Nadler MB; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Department of Medicine, The University of Toronto, Toronto, ON, Canada. .
Wilson BE; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Department of Medicine, The University of Toronto, Toronto, ON, Canada.; Kingston Health Sciences Centre, Kingston, ON, Canada.
Desnoyers A; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Department of Medicine, The University of Toronto, Toronto, ON, Canada.; Université de Sherbrooke, Sherbrooke, QC, Canada.
Valiente CM; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Department of Medicine, The University of Toronto, Toronto, ON, Canada.
Saleh RR; Division of Medical Division of Medical Oncology, McGill University Health Centre, Montreal, QC, Canada.
Amir E; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and Department of Medicine, The University of Toronto, Toronto, ON, Canada.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 03; Vol. 14 (1), pp. 459. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/drug therapy
United States ; Humans ; Female ; Drug Approval/methods ; Sample Size ; United States Food and Drug Administration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Increasing Functionality of Fish Leather by Chemical Surface Modifications.
Autorzy:
Zilberfarb A; Department of Polymer Materials Engineering, Shenkar College of Engineering and Design, Anna Frank 12, Ramat Gan 5252626, Israel.
Cohen G; Department of Polymer Materials Engineering, Shenkar College of Engineering and Design, Anna Frank 12, Ramat Gan 5252626, Israel.
Amir E; Department of Polymer Materials Engineering, Shenkar College of Engineering and Design, Anna Frank 12, Ramat Gan 5252626, Israel.
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Źródło:
Polymers [Polymers (Basel)] 2023 Sep 27; Vol. 15 (19). Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-Diabetic and Anti-Adipogenic Effect of Harmine in High-Fat-Diet-Induced Diabetes in Mice.
Autorzy:
Morsy MHE; Department of Zoology, Faculty of Science, Arish University, Arish 45511, Egypt.; Department of Zoology, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Nabil ZI; Department of Zoology, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Darwish ST; Department of Zoology, Faculty of Science, Arish University, Arish 45511, Egypt.
Al-Eisa RA; Department of Biology, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Mehana AE; Department of Zoology, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
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Źródło:
Life (Basel, Switzerland) [Life (Basel)] 2023 Aug 05; Vol. 13 (8). Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tyrosol and Olive Oil Ameliorate Sodium Arsenate-Induced Nephrotoxicity by Modulating of Oxidative Stress and Histological Changes in Mice.
Autorzy:
Zargari M; Department of Biochemistry, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammadian M; Department of Biology, Faculty of Science, Golestan University, Gorgan, Iran.
Malekshah AK; Department of Anatomy, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Mianabadi M; Department of Biology, Faculty of Science, Golestan University, Gorgan, Iran.
Mogaddam AE; Department of Anatomy, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Amiri FT; Department of Anatomy, Faculty of Medicine, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
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Źródło:
International journal of preventive medicine [Int J Prev Med] 2023 Apr 26; Vol. 14, pp. 47. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Perceived guideline clarity impacts guideline-concordant care for breast cancer screening in women age 40-49.
Autorzy:
Nadler MB; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre, 700 University Avenue, Toronto, ON, M5G 1Z5, Canada. .; Department of Medicine, University of Toronto, Toronto, ON, Canada. .
Corrado AM; The Peter Gilgan Centre for Women's Cancers, Women's College Hospital, Toronto, Canada.
Wilson BE; Kingston Health Sciences Centre, Kingston, ON, Canada.
Desnoyers A; University of Lavel, Quebec City, QC, Canada.
Amir E; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre, 700 University Avenue, Toronto, ON, M5G 1Z5, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.
Ivers N; Women's College Hospital, Toronto, Canada.; Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
Desveaux L; The Peter Gilgan Centre for Women's Cancers, Women's College Hospital, Toronto, Canada.; Women's College Hospital, Toronto, Canada.; Trillium Health Partners, Toronto, Canada.
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Źródło:
BMC women's health [BMC Womens Health] 2023 Feb 20; Vol. 23 (1), pp. 75. Date of Electronic Publication: 2023 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/diagnosis
Physicians*
Humans ; Female ; Adult ; Middle Aged ; Canada ; Early Detection of Cancer ; Patient Care
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association between control group therapy and magnitude of clinical benefit of cancer drugs.
Autorzy:
Molto C; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, 610 University Ave, Toronto, ON, M5G 2M9, Canada.
Tibau A; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Department of Medicine of Universitat Autònoma de Barcelona, Institut d'investigacio Biomedica Sant Pau, Barcelona, Catalonia, Spain.
Bujosa A; Medical Oncology Department, Hospital Son Llàtzer, Palma de Mallorca, Balearic Islands, Spain.
Tapia JC; Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Department of Medicine of Universitat Autònoma de Barcelona, Institut d'investigacio Biomedica Sant Pau, Barcelona, Catalonia, Spain.
Mittal A; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, 610 University Ave, Toronto, ON, M5G 2M9, Canada.
Tamimi F; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, 610 University Ave, Toronto, ON, M5G 2M9, Canada.
Amir E; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and University of Toronto, 610 University Ave, Toronto, ON, M5G 2M9, Canada. eitan.amir@uhn.ca.
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 09; Vol. 12 (1), pp. 21342. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/drug therapy
Antineoplastic Agents*/therapeutic use
Humans ; Control Groups ; Medical Oncology ; Quality of Life
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy and Safety of the Addition of Internal Mammary Irradiation to Standard Adjuvant Radiation in Early-Stage Breast Cancer: A Systematic Review and Meta-Analysis.
Autorzy:
Korzets Y; Institute of Oncology, Tel Aviv Sourasky Medical Center, Weizmann St. 6, Tel-Aviv 6423906, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Chaim Levanon St. 30, Tel-Aviv 6997801, Israel.
Levitas D; Oncology Institute, Shaare Zedek Medical Center, Shmuel Bait St. 12, Jerusalem 9103102, Israel.; Faculty of Medicine, Hebrew University, Ein Kerem. P.O. Box 12271, Jerusalem 9112102, Israel.
Grubstein A; Sackler Faculty of Medicine, Tel Aviv University, Chaim Levanon St. 30, Tel-Aviv 6997801, Israel.; Department of Imaging, Rabin Medical Center, Jabotinsky St. 39, Petah Tikva 4941492, Israel.
Corn BW; Oncology Institute, Shaare Zedek Medical Center, Shmuel Bait St. 12, Jerusalem 9103102, Israel.; Faculty of Medicine, Hebrew University, Ein Kerem. P.O. Box 12271, Jerusalem 9112102, Israel.
Amir E; Princess Margaret Cancer Centre, University of Toronto, 610 University Ave, Toronto, ON M5G 2C1, Canada.
Goldvaser H; Oncology Institute, Shaare Zedek Medical Center, Shmuel Bait St. 12, Jerusalem 9103102, Israel.; Faculty of Medicine, Hebrew University, Ein Kerem. P.O. Box 12271, Jerusalem 9112102, Israel.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2022 Sep 17; Vol. 29 (9), pp. 6657-6673. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Brachytherapy*
Breast Neoplasms*/radiotherapy
Breast Neoplasms*/surgery
Disease-Free Survival ; Female ; Humans ; Lymph Nodes/pathology ; Radiotherapy, Adjuvant
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical benefit of cancer drugs approved in Switzerland 2010-2019.
Autorzy:
Adam R; Faculty of Medicine, University of Basel, Basel, Switzerland.
Tibau A; Oncology Department, Departament de Medicina de la Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau, Barcelona, Spain.
Molto Valiente C; Oncology Department, Departament de Medicina de la Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau, Barcelona, Spain.
Šeruga B; Institute of Oncology Ljubljana and Faculty of Medicine, Department of Medical Oncology, University of Ljubljana, Ljubljana, Slovenia.
Ocaña A; Experimental Therapeutics Unit, Medical Oncology Department, Hospital Clínico Universitario San Carlos and IdISSC, Madrid, Spain.
Amir E; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Center and the University of Toronto, Toronto, ON, Canada.
Templeton AJ; Faculty of Medicine, University of Basel, Basel, Switzerland.; Department of Medical Oncology, St. Claraspital, Basel, Switzerland.; St. Clara Research Ltd., Basel, Switzerland.
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Źródło:
PloS one [PLoS One] 2022 Jun 10; Vol. 17 (6), pp. e0268545. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Humans ; Medical Oncology ; Quality of Life ; Switzerland
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A retrospective analysis of changes in distant and breast cancer related disease-free survival events in adjuvant breast cancer trials over time.
Autorzy:
Wilson BE; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, 700 University Ave, 700U, 7W305, Toronto, ON, M5G 2M9, Canada. .; University of New South Wales, Kensington, NSW, Australia. .
Desnoyers A; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, 700 University Ave, 700U, 7W305, Toronto, ON, M5G 2M9, Canada.
Al-Showbaki L; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, 700 University Ave, 700U, 7W305, Toronto, ON, M5G 2M9, Canada.
Nadler MB; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, 700 University Ave, 700U, 7W305, Toronto, ON, M5G 2M9, Canada.
Amir E; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, 700 University Ave, 700U, 7W305, Toronto, ON, M5G 2M9, Canada.
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Źródło:
Scientific reports [Sci Rep] 2022 Apr 15; Vol. 12 (1), pp. 6352. Date of Electronic Publication: 2022 Apr 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/drug therapy
Chemotherapy, Adjuvant ; Disease-Free Survival ; Female ; Humans ; Progression-Free Survival ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Impact of Cognitive Impairment on Treatment Toxicity, Treatment Completion, and Survival among Older Adults Receiving Chemotherapy: A Systematic Review.
Autorzy:
Sattar S; College of Nursing, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Haase K; Faculty of Applied Science, School of Nursing, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Tejero I; Division of Geriatric Medicine and General Internal Medicine, Department of Medicine, Sinai Health System, Toronto, ON M5G 1X5, Canada.; Division of Geriatric Medicine and General Internal Medicine, Department of Medicine, University Health Network, Toronto, ON M5G 2C4, Canada.
Bradley C; Library, University of Regina, Regina, SK S4S 0A2, Canada.
Mariano C; Department of Medical Oncology, BC Cancer Vancouver Centre, Vancouver, BC V5Z 4E6, Canada.
Kilgour H; Faculty of Applied Science, School of Nursing, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Verma R; School of Healthcare Sciences, Cardiff University, Wales CF14 4XN, UK.
Amir E; Division of Medical Oncology and Hematology, University Health Network, Toronto, ON M5G 2C1, Canada.; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Alibhai S; Division of Geriatric Medicine and General Internal Medicine, Department of Medicine, University Health Network, Toronto, ON M5G 2C4, Canada.; Department of Medicine, Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON M5S 1A8, Canada.
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Źródło:
Cancers [Cancers (Basel)] 2022 Mar 21; Vol. 14 (6). Date of Electronic Publication: 2022 Mar 21.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluation of Risk Prediction Models to Identify Cancer Therapeutics Related Cardiac Dysfunction in Women with HER2+ Breast Cancer.
Autorzy:
Suntheralingam S; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON M5G 2N2, Canada.
Fan CS; Rogers Computational Program, Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, Toronto, ON M5G 2N2, Canada.
Calvillo-Argüelles O; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON M5G 2N2, Canada.; Department of Cardiology, Department of Medical Oncology, Health Sciences North (HSN), Division of Clinical Sciences, Northern Ontario School of Medicine (NOSM), Sudbury, ON P3E 2C6, Canada.; Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON M5T 3M6, Canada.
Abdel-Qadir H; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON M5G 2N2, Canada.; Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON M5T 3M6, Canada.; Women's College Hospital (WCH), Toronto, ON M5S 1B2, Canada.
Amir E; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.
Thavendiranathan P; Ted Rogers Program in Cardiotoxicity Prevention, Peter Munk Cardiac Center, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON M5G 2N2, Canada.
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Źródło:
Journal of clinical medicine [J Clin Med] 2022 Feb 05; Vol. 11 (3). Date of Electronic Publication: 2022 Feb 05.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study.
Autorzy:
Mohamed DI; Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Abou-Bakr DA; Department of Physiology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
Ezzat SF; Department of Histology and Cell Biology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.
El-Kareem HFA; Zoology Department, Faculty of Science, Ain Shams University, Cairo 11566, Egypt.
Nahas HHA; Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Saad HA; Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Mehana AE; Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Institute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Str. 2, 12489 Berlin, Germany.
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Źródło:
Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2021 Nov 25; Vol. 14 (12). Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Feasibility of a Remotely Delivered Strength and Balance Training Program for Older Adults with Cancer.
Autorzy:
Sattar S; College of Nursing, University of Saskatchewan, Regina, SK S4T 0H8, Canada.
Haase K; Faculty of Applied Science, School of Nursing, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Penz K; College of Nursing, University of Saskatchewan, Regina, SK S4T 0H8, Canada.
Effa C; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada.
Nedeljak J; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada.
Chalchal H; Department of Medicine, University of Saskatchewan, Saskatoon, SK S7N 0X8, Canada.
Souied O; Department of Medicine, University of Saskatchewan, Saskatoon, SK S7N 0X8, Canada.
Amir E; Department of Medical Oncology, University Health Network, Toronto, ON M5G 2C1, Canada.
Pitters E; Patient Representative, Ajax, ON L1S 5C2, Canada.
Campbell D; College of Nursing, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Alibhai S; Department of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON M5T 3M6, Canada.; General Internal Medicine, University Health Network, Toronto, ON M5G 2C4, Canada.
McNeely ML; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB T6G 2G4, Canada.; Department of Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2021 Nov 02; Vol. 28 (6), pp. 4408-4419. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/therapy
Resistance Training*
Accidental Falls/prevention & control ; Aged ; Exercise Therapy ; Feasibility Studies ; Humans ; Postural Balance
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fragility of randomized trials supporting cancer drug approvals stratified by approval pathway and review designations.
Autorzy:
Wilson BE; Princess Margaret Cancer Centre, Department of Medical Oncology, University of Toronto, Toronto, ON, Canada.; University of New South Wales, Kensington, NSW, Australia.
Desnoyers A; Princess Margaret Cancer Centre, Department of Medical Oncology, University of Toronto, Toronto, ON, Canada.
Nadler MB; Princess Margaret Cancer Centre, Department of Medical Oncology, University of Toronto, Toronto, ON, Canada.
Tibau A; Oncology Department, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau, and Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.
Amir E; Princess Margaret Cancer Centre, Department of Medical Oncology, University of Toronto, Toronto, ON, Canada.
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Źródło:
Cancer medicine [Cancer Med] 2021 Aug; Vol. 10 (16), pp. 5405-5414. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Drug Approval/*statistics & numerical data
Neoplasm Recurrence, Local/*epidemiology
Neoplasms/*drug therapy
Randomized Controlled Trials as Topic/*statistics & numerical data
Consent Forms/statistics & numerical data ; Disease-Free Survival ; Humans ; Kaplan-Meier Estimate ; Lost to Follow-Up ; Neoplasm Recurrence, Local/prevention & control ; Neoplasms/mortality ; Progression-Free Survival ; Randomized Controlled Trials as Topic/standards ; Sample Size ; Time Factors ; United States ; United States Food and Drug Administration/standards
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Efficacy, safety and tolerability of drugs studied in phase 3 randomized controlled trials in solid tumors over the last decade.
Autorzy:
Ribnikar D; Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.; Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada.
Goldvaser H; Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada.; Rabin Medical Center, Davidoff Cancer Center, Beilinson Hospital, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Veitch ZW; Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada.
Ocana A; Drug Development Program, Hospital Clinico San Carlos and CIBERONC, Madrid, Spain.; Translational Oncology Laboratory. Regional Center for Biomedical Research (CRIB), Castilla La Mancha University, Albacete, Spain.
Templeton AJ; Department of Oncology, St. Claraspital Basel, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.
Šeruga B; Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Amir E; Division of Medical Oncology and Hematology, University of Toronto and Princess Margaret Cancer Centre, 610 University Ave, 700U, 7-721, Toronto, ON, M5G 2M9, Canada. eitan.amir@uhn.ca.
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Źródło:
Scientific reports [Sci Rep] 2021 May 25; Vol. 11 (1), pp. 10843. Date of Electronic Publication: 2021 May 25.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Antineoplastic Agents/*therapeutic use
Neoplasms/*drug therapy
Antineoplastic Agents/adverse effects ; Clinical Trials, Phase III as Topic ; Female ; Humans ; Male ; Odds Ratio ; Randomized Controlled Trials as Topic ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Metastatic Testicular Cancer.
Autorzy:
Ribnikar D; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Stukalin I; Department of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
Bedard PL; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Hamilton RJ; Princess Margaret Cancer Centre, Department of Surgery, University Health Network, 610 University Ave 3-130, Toronto, ON M5G 2C1, Canada.
Jewett M; Princess Margaret Cancer Centre, Department of Surgery, University Health Network, 610 University Ave 3-130, Toronto, ON M5G 2C1, Canada.
Warde P; Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Chung P; Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Anson-Cartwright L; Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Templeton AJ; Department of Oncology, St. Claraspital Basel, and Faculty of Medicine, University of Basel, CH-4058 Basel, Switzerland.
Amir E; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Hansen AR; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Heng DYC; Department of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
Lewin J; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2020 Dec 21; Vol. 28 (1), pp. 107-114. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms, Germ Cell and Embryonal*/diagnosis
Neoplasms, Germ Cell and Embryonal*/drug therapy
Testicular Neoplasms*/diagnosis
Testicular Neoplasms*/drug therapy
Humans ; Lymphocytes ; Male ; Neutrophils ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Associations between safety, tolerability, and toxicity and the reporting of health-related quality of life in phase III randomized trials in common solid tumors.
Autorzy:
Saleh RR; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Meti N; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Ribnikar D; Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Goldvaser H; Davidoff Cancer Center, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ocana A; Experimental Therapeutics Unit, Medical Oncology Department, Hospital Clínico San Carlos, and IdISSC, Madrid, Spain.; Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain.; Centro Regional de Investigaciones Biomédicas, Castilla-La Mancha University, Ciudad Real, Spain.
Templeton AJ; Department of Oncology, St. Claraspital, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.
Seruga B; Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Amir E; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
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Źródło:
Cancer medicine [Cancer Med] 2020 Nov; Vol. 9 (21), pp. 7888-7895. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji:
Journal Article
MeSH Terms:
Patient Reported Outcome Measures*
Quality of Life*
Antineoplastic Agents/*therapeutic use
Neoplasms/*drug therapy
Antineoplastic Agents/adverse effects ; Clinical Trials, Phase III as Topic ; Humans ; Neoplasms/diagnosis ; Neoplasms/mortality ; Randomized Controlled Trials as Topic ; Research Design ; Risk Assessment ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hybrid Antibacterial and Electro-conductive Coating for Textiles Based on Cationic Conjugated Polymer.
Autorzy:
Jarach N; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Meridor D; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Buzhor M; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Raichman D; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Dodiuk H; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Kenig S; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
Amir E; Department of Polymer Materials Engineering, Shenkar College, 5252626 Ramat-Gan, Israel.
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Źródło:
Polymers [Polymers (Basel)] 2020 Jul 08; Vol. 12 (7). Date of Electronic Publication: 2020 Jul 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Influence of Competing Risks on Estimates of Recurrence Risk and Breast Cancer-specific Mortality in Analyses of the Early Breast Cancer Trialists Collaborative Group.
Autorzy:
Saleh RR; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada.
Nadler MB; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada.
Desnoyers A; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada.
Rodin DL; Division of Radiation Oncology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada.
Abdel-Qadir H; Department of Medicine, Women's College Hospital, Toronto, ON, Canada.; Division of Cardiology, Peter Munk Cardiac Centre and the Ted Rogers Centre for Heart Research, University Health Network, Toronto, ON, Canada.; Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.; Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada.
Amir E; Division of Medical Oncology & Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada. eitan.amir@uhn.ca.
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Źródło:
Scientific reports [Sci Rep] 2020 Mar 05; Vol. 10 (1), pp. 4091. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Statistical*
Breast Neoplasms/*mortality
Neoplasm Recurrence, Local/*mortality
Risk Assessment/*methods
Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Canada/epidemiology ; Female ; Humans ; Incidence ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/pathology ; Prognosis ; Survival Rate
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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