Autor: "Amouyel P" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping.
Autorzy:: Belloy ME; Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA. .
Eger SJ; Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.
Le Guen Y; Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.
Damotte V; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
Ahmad S; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Ikram MA; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.
Ramirez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany.; Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Cluster of Excellence Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Tsolaki AC; 1st Department of Neurology, AHEPA Hospital, Aristotle University of Thessaloniki, Athens, Greece.
Rossi G; Unit of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Jansen IE; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije University, Amsterdam, The Netherlands.
de Rojas I; Research Center and Memory Clinic, ACE Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
Parveen K; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative diseases and Geriatric Psychiatry, Medical Faculty, University Hospital Bonn, Bonn, Germany.
Sleegers K; Complex Genetics of Alzheimer's Disease Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Ingelsson M; Department of Public Health and Carins Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Yliopistonranta 1E, 70211, Kuopio, Finland.
Amin N; Department of Epidemiology, ErasmusMC, Rotterdam, The Netherlands.; Nuffield Department of Population Health Oxford University, Oxford, UK.
Andreassen O; NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Sánchez-Juan P; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain.; Neurology Service, Marqués de Valdecilla University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
Kehoe P; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Amouyel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
Sims R; Division of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Wales, UK.
Frikke-Schmidt R; Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
van der Flier WM; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
Lambert JC; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, Lille, France.
He Z; Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.; Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA.
Han SS; Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA.; Department of Neurosurgery, Stanford University, Stanford, CA, 94304, USA.
Napolioni V; School of Biosciences and Veterinary Medicine, University of Camerino, 62032, Camerino, Italy.
Greicius MD; Department of Neurology and Neurological Sciences - Greicius lab, Stanford University, 290 Jane Stanford Way, Stanford, CA, 94304, USA.; Pokaż więcej
Corporate Authors:: European Alzheimer & Dementia BioBank (EADB)
Źródło:: Alzheimer's research & therapy [Alzheimers Res Ther] 2022 Feb 04; Vol. 14 (1), pp. 22. Date of Electronic Publication: 2022 Feb 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease*/genetics
Apolipoproteins E*/genetics
Apolipoprotein E4/genetics ; Genetic Predisposition to Disease/genetics ; Genotype ; Humans ; Middle Aged ; Quality Control

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Skocz do pozycji: 2.

Tytuł:: The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects.
Autorzy:: Lambert E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Saha O; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Soares Landeira B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Melo de Farias AR; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.; Brain Institute, Federal University of Rio Grande do Norte, Natal, Brazil.
Hermant X; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Carrier A; Univ. Lille, Inserm, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR 8199 EGID, F-59000, Lille, France.
Pelletier A; Univ. Lille, Inserm, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR 8199 EGID, F-59000, Lille, France.
Gadaut J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Davoine L; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Dupont C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Amouyel P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Bonnefond A; Univ. Lille, Inserm, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR 8199 EGID, F-59000, Lille, France.
Lafont F; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, F-59000, Lille, France.
Abdelfettah F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Verstreken P; VIB Center for Brain and Disease Research, KU Leuven, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Chapuis J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Barois N; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, F-59000, Lille, France.; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US41-UMS2014-PLBS, F-59000, Lille, France.
Delahaye F; Univ. Lille, Inserm, CNRS, CHU Lille, Institut Pasteur de Lille, U1283-UMR 8199 EGID, F-59000, Lille, France.
Dermaut B; Department of Biomolecular Medicine, Faculty of Medicine and Health sciences, Ghent University, 9000, Ghent, Belgium.; Centre for Medical Genetics, Ghent University Hospital, 9000, Ghent, Belgium.
Lambert JC; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France.
Costa MR; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France. .; Brain Institute, Federal University of Rio Grande do Norte, Natal, Brazil. .
Dourlen P; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1167 - RID-AGE - Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement, F-59000, Lille, France. .; Pokaż więcej
Źródło:: Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Jan 08; Vol. 10 (1), pp. 4. Date of Electronic Publication: 2022 Jan 08.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease/*genetics
Drosophila Proteins/*genetics
Endosomes/*genetics
Nerve Degeneration/*genetics
Neurons/*pathology
Transcription Factors/*genetics
Alzheimer Disease/pathology ; Animals ; Animals, Genetically Modified ; Brain/metabolism ; Brain/pathology ; Drosophila melanogaster ; Endosomes/metabolism ; Endosomes/pathology ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Nerve Degeneration/pathology ; Neurons/metabolism

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Skocz do pozycji: 3.

Tytuł:: Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
Autorzy:: Baker E; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Sims R; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Leonenko G; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Frizzati A; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Harwood JC; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Grozeva D; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Morgan K; Human Genetics, School of Life Sciences, Life Sciences Building A27, University Park, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.
Passmore P; Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University, Belfast, United Kingdom.
Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, United Kingdom.
Powell J; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, United Kingdom.; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Brayne C; Institute of Public Health, University of Cambridge, Cambridge, United Kingdom.
Gill M; Mercer's Institute for Research on Ageing, St. James' Hospital, Dublin, Ireland.; James Hospital and Trinity College, Dublin, Ireland.
Mead S; MRC Prion Unit at UCL, Institute of Prion Diseases, London, United Kingdom.
Bossù P; Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Department of Clinical and Behavioral Neurology, Rome, Italy.
Spalletta G; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
Goate AM; Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri, United States of America.
Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri, United States of America.
Maier W; German Centre for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Heun R; Department of Psychiatry and Psychotherapy, University of Bonn, 53127, Bonn, Germany.
Jessen F; German Centre for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, 50937 Cologne, Germany.
Peters O; Department of Psychiatry and Psychotherapy, Charité Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, 80336, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
FröLich L; Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
Ramirez A; Department of Psychiatry and Psychotherapy, University of Cologne, 50937 Cologne, Germany.; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
Jones L; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Hardy J; Department of Molecular Neuroscience, UCL, Institute of Neurology, London, United Kingdom.
Ivanov D; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Hill M; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Holmans P; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
Allen ND; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Morgan BP; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Amouyel P; Univ. Lille, Inserm, CHU Lille University Hospital, Institut Pasteur de Lille, LabEx DISTALZ-UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related, F-59000 Lille, France.
Williams J; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.
Escott-Price V; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.; UK Dementia Research Institute at Cardiff University, Cardiff, United Kingdom.; Pokaż więcej
Corporate Authors:: GERAD/PERADES
CHARGE
ADGC
EADI
IGAP consortia
Źródło:: PloS one [PLoS One] 2019 Jul 08; Vol. 14 (7), pp. e0218111. Date of Electronic Publication: 2019 Jul 08 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Human*
Polymorphism, Single Nucleotide*
Alzheimer Disease/*genetics
Nuclear Receptor Subfamily 1, Group F, Member 1/*genetics
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/*genetics
Proteins/*genetics
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Centrosome/metabolism ; Centrosome/pathology ; Cholesterol/genetics ; Cholesterol/metabolism ; Circadian Rhythm/genetics ; DNA Damage/genetics ; DNA Repair/genetics ; Energy Metabolism/genetics ; Female ; Genome-Wide Association Study ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Nuclear Receptor Subfamily 1, Group F, Member 1/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Proteins/metabolism

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Skocz do pozycji: 4.

Tytuł:: miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer's disease.
Autorzy:: Delay C; NSERM U1167, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) Research Group, Lille, France.; Institut Pasteur de Lille, Lille, France.; University of Lille, Lille, France.
Grenier-Boley B; NSERM U1167, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) Research Group, Lille, France.; Institut Pasteur de Lille, Lille, France.; University of Lille, Lille, France.
Amouyel P; NSERM U1167, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) Research Group, Lille, France.; Institut Pasteur de Lille, Lille, France.; University of Lille, Lille, France.
Dumont J; NSERM U1167, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) Research Group, Lille, France.; Institut Pasteur de Lille, Lille, France.; University of Lille, Lille, France.
Lambert JC; NSERM U1167, Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement (RID-AGE) Research Group, Lille, France. .; Institut Pasteur de Lille, Lille, France. .; University of Lille, Lille, France. .; Pokaż więcej
Źródło:: Alzheimer's research & therapy [Alzheimers Res Ther] 2016 May 24; Vol. 8 (1), pp. 20. Date of Electronic Publication: 2016 May 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Polymorphism, Single Nucleotide*
Alzheimer Disease/*genetics
MicroRNAs/*genetics
3' Untranslated Regions ; Binding Sites ; Computer Simulation ; Genome-Wide Association Study ; HEK293 Cells ; HeLa Cells ; Humans

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Skocz do pozycji: 5.

Tytuł:: Association of Alzheimer's related genotypes with cognitive decline in multiple domains: results from the Three-City Dijon study.
Autorzy:: Vivot A; Bordeaux University, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique & CIC-1401, CHU de Bordeaux, Pole de Sante Publique, Bordeaux, France.; Department of Social and Behavorial Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Glymour MM; Department of Social and Behavorial Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Tzourio C; Bordeaux University, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique & CIC-1401, CHU de Bordeaux, Pole de Sante Publique, Bordeaux, France.
Amouyel P; Lille University, INSERM U744, Institut Pasteur de Lille, Lille, France.
Chêne G; Bordeaux University, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique & CIC-1401, CHU de Bordeaux, Pole de Sante Publique, Bordeaux, France.
Dufouil C; Bordeaux University, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique & CIC-1401, CHU de Bordeaux, Pole de Sante Publique, Bordeaux, France.; Pokaż więcej
Źródło:: Molecular psychiatry [Mol Psychiatry] 2015 Oct; Vol. 20 (10), pp. 1173-8. Date of Electronic Publication: 2015 Jun 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Alzheimer Disease/*genetics
Cognition Disorders/*genetics
Adaptor Proteins, Signal Transducing/genetics ; Aged ; Aged, 80 and over ; Alzheimer Disease/psychology ; Apolipoproteins E/genetics ; Apolipoproteins E/metabolism ; Cognition Disorders/psychology ; Cohort Studies ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Longitudinal Studies ; Male ; Memory ; Nuclear Proteins/genetics ; Polymorphism, Genetic ; Prospective Studies ; Receptors, Complement 3b/genetics ; Risk Factors ; Tumor Suppressor Proteins/genetics

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Skocz do pozycji: 6.

Tytuł:: PLD3 and sporadic Alzheimer's disease risk.
Autorzy:: Lambert JC; INSERM, U744, Université Lille 2, Institut Pasteur de Lille, Lille 59000, France.
Grenier-Boley B; INSERM, U744, Université Lille 2, Institut Pasteur de Lille, Lille 59000, France.
Bellenguez C; INSERM, U744, Université Lille 2, Institut Pasteur de Lille, Lille 59000, France.
Pasquier F; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Université Lille 2, Lille 59000, France.
Campion D; CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen 76031, France.
Dartigues JF; Inserm U897, Victor Segalen University, Bordeaux 33076, France.
Berr C; INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier 34093, France.
Tzourio C; INSERM, U708, Victor Segalen University, Bordeaux, France.
Amouyel P; INSERM, U744, Université Lille 2, Institut Pasteur de Lille, Lille 59000, France.; Pokaż więcej
Źródło:: Nature [Nature] 2015 Apr 02; Vol. 520 (7545), pp. E1.
Typ publikacji:: Letter; Comment
MeSH Terms:: Alzheimer Disease/*genetics
Genetic Predisposition to Disease/*genetics
Genetic Variation/*genetics
Phospholipase D/*genetics
Female ; Humans ; Male

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Skocz do pozycji: 7.

Tytuł:: Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Autorzy:: Escott-Price V; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Bellenguez C; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France.
Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Choi SH; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Harold D; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Jones L; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Holmans P; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Gerrish A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Vedernikov A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Richards A; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
DeStefano AL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Lambert JC; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France.
Ibrahim-Verbaas CA; Department of Epidemiology and Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Naj AC; Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Sims R; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Jun G; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Beecham GW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America.
Grenier-Boley B; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France.
Russo G; Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland.
Thornton-Wells TA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America.
Denning N; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Smith AV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Icelandic Heart Association, Kopavogur, Iceland.
Chouraki V; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
Thomas C; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Ikram MA; Departments of Epidemiology, Neurology and Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.
Zelenika D; Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France.
Vardarajan BN; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America.
Kamatani Y; Fondation Jean Dausset- CEPH, Paris, France.
Lin CF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Schmidt H; Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Kunkle B; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America.
Dunstan ML; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Vronskaya M; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Johnson AD; NHLBI Cardiovascular Epidemiology and Human Genomics Branch, The Framingham Heart Study, Framingham, Massachusetts, United States of America.
Ruiz A; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain.
Bihoreau MT; Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France.
Reitz C; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America.
Pasquier F; Université Lille 2, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France.
Hollingworth P; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Hanon O; University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics department, Paris, France.
Fitzpatrick AL; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America; Departments of Epidemiology and Global Health, University of Washington, Seattle, Washington, United States of America.
Buxbaum JD; Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America; Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, United States of America; Departments of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America.
Campion D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France.
Crane PK; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Baldwin C; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America.
Becker T; German Center for Neurodegenerative Diseases (DZNE), Bonn, and Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.
Gudnason V; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Icelandic Heart Association, Kopavogur, Iceland.
Cruchaga C; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Craig D; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Amin N; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Berr C; INSERM U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France.
Lopez OL; Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
De Jager PL; Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts, United States of America.
Deramecourt V; Université Lille 2, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France.
Johnston JA; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Evans D; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.
Lovestone S; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom.
Letenneur L; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France.
Hernández I; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain.
Rubinsztein DC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.
Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland.
Sleegers K; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
Goate AM; Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America.
Fiévet N; Inserm U744, Lille, France; Institut Pasteur de Lille, Lille, France.
Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
Gill M; Discipline of Psychiatry, Trinity College, Dublin, Ireland.
Brown K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom.
Kamboh MI; Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Keller L; Aging Reasearch Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Barberger-Gateau P; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom.
McGuinness B; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Larson EB; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health, Seattle, Washington, United States of America.
Myers AJ; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida, United States of America.
Dufouil C; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France.
Todd S; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Wallon D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France.
Love S; University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, United Kingdom.
Rogaeva E; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.
Gallacher J; Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
George-Hyslop PS; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada; Cambridge Institute for Medical Research and Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
Clarimon J; Neurology Department. IIB Sant Pau. Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain; Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Lleo A; Neurology Department. IIB Sant Pau. Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain; Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
Bayer A; Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
Tsuang DW; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America.
Yu L; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America.
Tsolaki M; 3rd Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Bossù P; Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy.
Spalletta G; Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy.
Proitsi P; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom.
Collinge J; MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom.
Sorbi S; NEUROFARBA Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.
Garcia FS; Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.
Fox NC; Dementia Research Center, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom.
Hardy J; Department of Molecular Neuroscience and Reta Lilla Weston Laboratories, Institute of Neurology, London, United Kingdom.
Naranjo MC; Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.
Bosco P; IRCCS Associazione Oasi Maria SS, Troina, Italy.
Clarke R; Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom.
Brayne C; Cognitive Function and Ageing Study (CFAS), Institute of Public Health, University of Cambridge, Cambridge, United Kingdom.
Galimberti D; University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy.
Scarpini E; University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy.
Bonuccelli U; Neurological Clinic, University of Pisa, Pisa, Italy.
Mancuso M; Neurological Clinic, University of Pisa, Pisa, Italy.
Siciliano G; Neurological Clinic, University of Pisa, Pisa, Italy.
Moebus S; Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Mecocci P; Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.
Zompo MD; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Maier W; Department of Psychiatry and Psychotherapy, University of Bonn, Germany and German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany.
Hampel H; Department of Psychiatry, University of Frankfurt am Main, Frankfurt am Main, Germany (H.H.); Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany.
Pilotto A; Gerontology and Geriatrics Research Laboratory, I.R.C.C.S. Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.
Frank-García A; Centro de Biología Molecular Severo Ochoa (CSIC-UAM); Madrid, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Instituto de Investigación Sanitaria 'Hospital la Paz' (IdIPaz), Madrid, Spain.
Panza F; Department of Geriatrics,Center for Aging Brain,University of Bari, Bari, Italy.
Solfrizzi V; Department of Geriatrics,Center for Aging Brain,University of Bari, Bari, Italy.
Caffarra P; Department of Neuroscience-University of Parma, Parma, Italy; Center for Cognitive Disorders AUSL, Parma, Italy.
Nacmias B; NEUROFARBA Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy; Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.
Perry W; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America.
Mayhaus M; Department Of Psychiatry, University Hospital, Saarland, Germany.
Lannfelt L; Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.
Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.
Pichler S; Department Of Psychiatry, University Hospital, Saarland, Germany.
Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
Ingelsson M; Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.
Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, United States of America.
Alvarez V; Genetica molecular-Huca-Oviedo, Oviedo, Spain.
Zou F; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
Coto E; Genetica molecular-Huca-Oviedo, Oviedo, Spain.
Hamilton-Nelson KL; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America.
Gu W; Department of Psychiatry, University Hospital, Saarland, Germany.
Razquin C; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.
Pastor P; Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain; CIBERNED, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
Mateo I; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IFIMAV), Santander, Spain.
Owen MJ; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Faber KM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America.
Jonsson PV; University of Iceland, Faculty of Medicine, Reykjavik, Iceland; Landspitali University Hospital, Reykjavik, Iceland.
Combarros O; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IFIMAV), Santander, Spain.
O'Donovan MC; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.
Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Soininen H; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Blacker D; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
Mead S; MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom.
Mosley TH Jr; Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
Bennett DA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America.
Fratiglioni L; Aging Research Center, Department Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Department Geriatric Medicine, Genetics Unit, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, United Kingdom.
de Bruijn RF; Departments of Neurology and Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Passmore P; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
Montine TJ; Department of Pathology, University of Washington, Seattle, Washington, United States of America.
Bettens K; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America.
Brice A; INSERM UMR_S975-CNRS UMR 7225, Université Pierre et Marie Curie, Centre de recherche de l'Institut du Cerveau et de la Moëlle épinière-CRICM, Hôpital de la Salpêtrière, Paris France; AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France.
Morgan K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom.
Foroud TM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America.
Kukull WA; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
Hannequin D; CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France.
Powell JF; King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom.
Nalls MA; Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America.
Ritchie K; INSERM U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France; Imperial College, London, United Kingdom.
Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah, United States of America.
Boerwinkle E; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America; Human Genetics Center and Div. of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas, United States of America.
Riemenschneider M; Department of Psychiatry, University Hospital, Saarland, Germany.
Boada M; Memory Clinic of Fundació ACE. Institut Català de Neurociències Aplicades, Barcelona, Spain; Hospital Universitari Vall d'Hebron - Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona, Spain.
Hiltunen M; Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
Martin ER; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America.
Schmidt R; Department of Neurology, Medical University Graz, Graz, Austria.
Rujescu D; Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany.
Dartigues JF; Inserm U897, Victor Segalen University, F-33076, Bordeaux, France; Centre de Mémoire de Ressources et de Recherche de Bordeaux, CHU de Bordeaux, Bordeaux, France.
Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University New York, New York, United States of America; Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America.
Tzourio C; Inserm U708, Victor Segalen University, Bordeaux, France.
Hofman A; Departments of Epidemiology, Neurology and Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.
Nöthen MM; Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, and German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany.
Graff C; Department Geriatric Medicine, Genetics Unit, Karolinska University Hospital Huddinge, Stockholm, Sweden; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, KIADRC, Stockholm, Sweden.
Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America.
Haines JL; Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, United States of America; Department of Epidemiology & Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America.
Lathrop M; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America; Fondation Jean Dausset- CEPH, Paris, France; McGill University and Génome Québec Innovation Centre, Montreal, Canada.
Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America; Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America.
Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America.
Van Broeckhoven C; Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
Farrer LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, United States of America; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
van Duijn CM; Netherlands Consortium for Healthy Aging, Leiden, The Netherlands; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands; Center for Medical Systems Biology, Leiden, The Netherlands.
Ramirez A; Department of Psychiatry and Psychotherapy and Institute of Human Genetics, University of Bonn, Bonn, Germany.
Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America; The Framingham Heart Study, Framingham, Massachusetts, United States of America.
Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
Amouyel P; Inserm U744, Lille, France; Université Lille 2, Lille, France; Institut Pasteur de Lille, Lille, France; CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France; Centre Hospitalier Régional Universitaire de Lille, Lille, France.
Williams J; Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom.; Pokaż więcej
Corporate Authors:: United Kingdom Brain Expression Consortium
Cardiovascular Health Study (CHS)
Źródło:: PloS one [PLoS One] 2014 Jun 12; Vol. 9 (6), pp. e94661. Date of Electronic Publication: 2014 Jun 12 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Alzheimer Disease/*genetics
Carrier Proteins/*genetics
Heat-Shock Proteins/*genetics
Case-Control Studies ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide ; Receptors, Antigen, B-Cell/genetics