- Tytuł:
- Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro.
- Autorzy:
- Źródło:
- Cancer investigation [Cancer Invest] 2007 Jun; Vol. 25 (4), pp. 240-8.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural
- MeSH Terms:
-
Lymphoma, Large B-Cell, Diffuse/*drug therapy
Protein-Tyrosine Kinases/*antagonists & inhibitors
RNA, Small Interfering/*therapeutic use
Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Chromosomes, Human, Pair 2 ; Chromosomes, Human, Pair 5 ; Down-Regulation ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/pathology ; Protein-Tyrosine Kinases/genetics ; Signal Transduction ; Translocation, Genetic
Czasopismo naukowe