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Tytuł :
Anemarrhena asphodeloides modulates gut microbiota and restores pancreatic function in diabetic rats.
Autorzy :
Yan D; Beijing Institute of Radiation Medicine, Beijing, China; China Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Fan P; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China.
Sun W; School of Bioengineering, Dalian University of Technology, Dalian, China.
Ding Q; Beijing Institute of Radiation Medicine, Beijing, China.
Zheng W; Beijing Institute of Radiation Medicine, Beijing, China.
Xiao W; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China.
Zhang B; School of Bioengineering, Dalian University of Technology, Dalian, China.
Zhang T; China Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Zhang T; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China.
Shi J; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China; Hebei Province Key Lab of Research and Application on Microbial Diversity, College of Life Sciences, Hebei University, Baoding, China.
Chen X; Beijing Institute of Radiation Medicine, Beijing, China.
Chen P; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China; Hebei Province Key Lab of Research and Application on Microbial Diversity, College of Life Sciences, Hebei University, Baoding, China.
Zhang J; Beijing Institute of Radiation Medicine, Beijing, China.
Hao Y; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Sun X; Beijing Institute of Radiation Medicine, Beijing, China.
Pang X; Beijing Institute of Radiation Medicine, Beijing, China.
Dong Y; School of Bioengineering, Dalian University of Technology, Dalian, China. Electronic address: .
Xu P; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences, Institute of Lifeomics, Beijing, China; Hebei Province Key Lab of Research and Application on Microbial Diversity, College of Life Sciences, Hebei University, Baoding, China. Electronic address: .
Yu L; China Pharmaceutical Culture Collection, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address: .
Ma B; Beijing Institute of Radiation Medicine, Beijing, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110954. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena*/chemistry
Bacteria/*drug effects
Blood Glucose/*drug effects
Diabetes Mellitus, Experimental/*drug therapy
Diabetes Mellitus, Type 2/*drug therapy
Gastrointestinal Microbiome/*drug effects
Hypoglycemic Agents/*pharmacology
Intestines/*microbiology
Islets of Langerhans/*drug effects
Plant Extracts/*pharmacology
Animals ; Bacteria/growth & development ; Biomarkers/blood ; Blood Glucose/metabolism ; Cell Proliferation/drug effects ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/microbiology ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/microbiology ; Diabetes Mellitus, Type 2/pathology ; Diet, High-Fat ; Dysbiosis ; Hypoglycemic Agents/isolation & purification ; Inflammation Mediators/blood ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Lipids/blood ; Male ; Peroxiredoxins/metabolism ; Plant Extracts/isolation & purification ; Rats, Wistar ; Streptozocin
Czasopismo naukowe
Tytuł :
[Improvement researches on quality standard of Anemarrhenae Rhizoma and its raw processed products].
Autorzy :
Huang Q; College of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology Heifei 230012, China.
Shao ZY; College of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China.
Wu DL; College of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology Heifei 230012, China.
Peng DY; College of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology Heifei 230012, China.
Jin CS; College of Pharmacy, Anhui University of Chinese Medicine Hefei 230012, China Anhui Province Key Laboratory of Traditional Chinese Medicine Decoction Pieces of New Manufacturing Technology Heifei 230012, China.
Zhang QL; Anhui Guangyintang Traditional Chinese Medicine Company Bozhou 236800, China.
Ma K; Bozhou Yonggang Traditional Chinese Medicine Company Bozhou 236800, China.
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Źródło :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2020 Dec; Vol. 45 (23), pp. 5701-5711.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena*
Drugs, Chinese Herbal*
Chromatography, High Pressure Liquid ; Reference Standards ; Rhizome
Czasopismo naukowe
Tytuł :
Lipidomics Analysis of Timosaponin BII in INS-1 Cells Induced by Glycolipid Toxicity and Its Relationship with Inflammation.
Autorzy :
Shi K; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Zhu J; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Chen D; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Ren C; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Guo M; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Wang J; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Wu X; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
Feng Y; Central Laboratory, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, 510006, P. R. China.
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Źródło :
Chemistry & biodiversity [Chem Biodivers] 2020 Apr; Vol. 17 (4), pp. e1900684. Date of Electronic Publication: 2020 Apr 03.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Glycolipids/*toxicity
Protective Agents/*chemistry
Saponins/*chemistry
Steroids/*chemistry
Anemarrhena/metabolism ; Animals ; Cell Survival/drug effects ; Discriminant Analysis ; Glutathione/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation/prevention & control ; Insulin-Secreting Cells/cytology ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Interleukin-1beta/metabolism ; Lipidomics/methods ; Macrophages/cytology ; Macrophages/drug effects ; Macrophages/metabolism ; Malondialdehyde/metabolism ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Principal Component Analysis ; Protective Agents/pharmacology ; Protective Agents/therapeutic use ; RAW 264.7 Cells ; Saponins/isolation & purification ; Saponins/pharmacology ; Saponins/therapeutic use ; Steroids/isolation & purification ; Steroids/pharmacology ; Steroids/therapeutic use
Czasopismo naukowe
Tytuł :
Extracts from Chinese herbs with anti-amyloid and neuroprotective activities.
Autorzy :
Bednarikova Z; Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia.
Gancar M; Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia.
Wang R; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Zheng L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Tang Y; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Luo Y; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Huang Y; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Spodniakova B; Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia.
Ma L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Rd., 200237 Shanghai, China.
Gazova Z; Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 May 15; Vol. 179, pp. 475-484. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article
MeSH Terms :
Abietanes/*pharmacology
Amyloid beta-Peptides/*metabolism
Benzofurans/*pharmacology
Neuroprotective Agents/*pharmacology
Peptide Fragments/*metabolism
Spirostans/*pharmacology
Alzheimer Disease/drug therapy ; Anemarrhena/chemistry ; Cell Line ; China ; Humans ; Plant Extracts ; Salvia miltiorrhiza/chemistry
Czasopismo naukowe
Tytuł :
Purification, characterization and immunostimulatory effects of polysaccharides from Anemarrhena asphodeloides rhizomes.
Autorzy :
Cao RA; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China; National Coarse Cereals Engineering Research Center, Heilongjiang Bayi Agricultural University, Daqing 163319, China; Agri-Food Processing and Engineering Technology Research Center of Heilongjiang Province, Daqing 163319, China.
Ji R; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Tabarsa M; Department of Seafood Processing, Faculty of Marine Sciences, Tarbiat Modares University, Noor 46414-356, Iran.
Zhang J; Heilongjiang Heyi Dairy Technology Co. Ltd., Daqing 163000, China.
Meng L; College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Zhang C; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Zhang J; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Wang L; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Wu R; College of Animal Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Wang C; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China; National Coarse Cereals Engineering Research Center, Heilongjiang Bayi Agricultural University, Daqing 163319, China. Electronic address: .
Jin C; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing 163319, China; National Coarse Cereals Engineering Research Center, Heilongjiang Bayi Agricultural University, Daqing 163319, China; College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China. Electronic address: .
You S; Department of Marine Food Science and Technology, Gangneung-Wonju National University, 120 Gangneung Daehangno, Gangneung, Gangwon 210-702, South Korea. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Mar 01; Vol. 172, pp. 550-559. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Gene Expression Regulation/*drug effects
Immunologic Factors/*pharmacology
Polysaccharides/*pharmacology
Rhizome/*chemistry
Animals ; Apoptosis/drug effects ; Apoptosis/genetics ; Carbohydrate Sequence ; Cell Line, Tumor ; Chromatin/chemistry ; Chromatin/drug effects ; Chromatin/immunology ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/immunology ; Cytoplasm/drug effects ; Cytoplasm/immunology ; Cytoplasm/pathology ; Immunologic Factors/chemistry ; Immunologic Factors/isolation & purification ; Interleukin-1/genetics ; Interleukin-1/immunology ; Mice ; Mitogen-Activated Protein Kinases/genetics ; Mitogen-Activated Protein Kinases/immunology ; Monosaccharides/chemistry ; Monosaccharides/isolation & purification ; Nitric Oxide/biosynthesis ; Polysaccharides/chemistry ; Polysaccharides/isolation & purification ; RAW 264.7 Cells ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/immunology ; Signal Transduction ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; Uronic Acids/chemistry ; Uronic Acids/isolation & purification
Czasopismo naukowe
Tytuł :
Biopharmaceutics and Pharmacokinetics of Timosaponin A-III by a Sensitive HPLC-MS/MS Method: Low Bioavailability Resulting from Poor Permeability and Solubility.
Autorzy :
Wang HQ; Department of Traditional Chinese Medicine, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 201112, China.
Gong XM; Department of Radiation Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Lan F; Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
Zhang YH; Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
Xia JE; Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
Zhang H; Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Guo JL; Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.
Liu M; Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
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Źródło :
Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2021; Vol. 22 (5), pp. 672-681.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents, Phytogenic/*pharmacokinetics
Saponins/*pharmacokinetics
Steroids/*pharmacokinetics
Administration, Intravenous ; Administration, Oral ; Anemarrhena/chemistry ; Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Biological Availability ; Biopharmaceutics ; Caco-2 Cells ; Chromatography, High Pressure Liquid ; Humans ; In Vitro Techniques ; Male ; Microsomes, Liver/metabolism ; Rats ; Rats, Sprague-Dawley ; Saponins/chemistry ; Solubility ; Steroids/chemistry ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Physicochemical properties and laxative effects of polysaccharides from Anemarrhena asphodeloides Bge. in loperamide-induced rats.
Autorzy :
Li X; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China.
Liu Y; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China.
Guan W; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China.
Xia Y; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China.
Zhou Y; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China.
Yang B; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China. Electronic address: .
Kuang H; Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, 24 Heping Road, Xiangfang District, Harbin, 150040, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2019 Aug 10; Vol. 240, pp. 111961. Date of Electronic Publication: 2019 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena*
Constipation/*drug therapy
Laxatives/*therapeutic use
Polysaccharides/*therapeutic use
Animals ; Constipation/chemically induced ; Loperamide ; Male ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The modifications of a fructan from Anemarrhena asphodeloides Bunge and their antioxidant activities.
Autorzy :
Zhang J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China.
Li Z; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China.
Zhou L; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China.
Bao J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China.
Xu J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People's Republic of China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 4435-4443. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Antioxidants/*pharmacology
Fructans/*chemistry
Acetates/pharmacology ; Biphenyl Compounds ; Carbohydrate Sequence ; Free Radical Scavengers/pharmacology ; Fructans/pharmacology ; Hydroxyl Radical ; Methylation ; Microscopy, Electron, Scanning ; Picrates ; Solubility ; Spectrophotometry, Ultraviolet ; Spectroscopy, Fourier Transform Infrared ; Sulfates/chemistry
Czasopismo naukowe
Tytuł :
One new benzophenone and one new 1,3-diphenylpropane from the fibrous roots of Anemarrhena asphodeloides Bge. and their cytotoxicity.
Autorzy :
Liao ZD; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Chen FF; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Xu FQ; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.; Anhui Key Laboratory of Modernized Chinese Materia Medica, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Zhang W; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.; Anhui Key Laboratory of Modernized Chinese Materia Medica, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Ren YS; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.; Anhui Key Laboratory of Modernized Chinese Materia Medica, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Wang CC; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
Wu DL; School of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.; Anhui Key Laboratory of Modernized Chinese Materia Medica, Anhui University of Traditional Chinese Medicine, Hefei, People's Republic of China.
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Źródło :
Natural product research [Nat Prod Res] 2020 Nov; Vol. 34 (21), pp. 3054-3060. Date of Electronic Publication: 2019 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Benzophenones/*chemistry
Benzophenones/*pharmacology
Propane/*analogs & derivatives
Antineoplastic Agents, Phytogenic/chemistry ; Benzophenones/isolation & purification ; Drug Screening Assays, Antitumor ; Hep G2 Cells ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Plant Roots/chemistry ; Propane/chemistry ; Propane/isolation & purification ; Propane/pharmacology ; Spectrometry, Mass, Electrospray Ionization
Czasopismo naukowe
Tytuł :
Gas chromatography-mass spectrometry-based trimethylsilyl-alditol derivatives for quantitation and fingerprint analysis of Anemarrhena asphodeloides Bunge polysaccharides.
Autorzy :
Xia YG; Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, PR China.
Wang TL; Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, PR China.
Sun HM; Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, PR China.
Liang J; Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, PR China.
Kuang HX; Key Laboratory of Chinese Materia Medica (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, PR China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2018 Oct 15; Vol. 198, pp. 155-163. Date of Electronic Publication: 2018 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena*
Polysaccharides/*analysis
Gas Chromatography-Mass Spectrometry ; Polysaccharides/chemistry ; Sugar Alcohols/chemistry ; Trimethylsilyl Compounds/chemistry
Czasopismo naukowe
Tytuł :
Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes.
Autorzy :
Wang M; Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, China.
Jiang W; Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, China.
Zhou J; Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, China.
Xue X; Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, China.
Yin C; Department of Pediatrics, Yidu Central Hospital of Weifang, Weifang, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 1064-1069.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Microsomes, Liver/*drug effects
Saponins/*pharmacology
Triterpenes/*pharmacology
Cytochrome P-450 Enzyme Inhibitors/administration & dosage ; Cytochrome P-450 Enzyme Inhibitors/isolation & purification ; Cytochrome P-450 Enzyme System/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Dose-Response Relationship, Drug ; Drug Interactions ; Humans ; Inhibitory Concentration 50 ; Microsomes, Liver/enzymology ; Saponins/administration & dosage ; Saponins/isolation & purification ; Time Factors ; Triterpenes/administration & dosage ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS.
Autorzy :
Xie L; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China.
Lee DY; Mailman Research Center, McLean Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: .
Shang Y; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China.
Cao X; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wang S; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liao J; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhang T; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: .
Dai R; School of Pharmacy, Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Oct; Vol. 77, pp. 153284. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Cyclooxygenase 2 Inhibitors/*pharmacology
Glycosides/*chemistry
Lipoxygenase Inhibitors/*pharmacology
Spirostans/*chemistry
Sterols/*chemistry
Animals ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Arachidonate 5-Lipoxygenase/chemistry ; Arachidonate 5-Lipoxygenase/genetics ; Arachidonate 5-Lipoxygenase/metabolism ; Chromatography, High Pressure Liquid ; Cyclooxygenase 2/chemistry ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/chemistry ; Drug Evaluation, Preclinical ; Glycosides/pharmacology ; Inflammation/drug therapy ; Lipoxygenase Inhibitors/chemistry ; Mass Spectrometry ; Molecular Docking Simulation ; Rats ; Rhizome/chemistry ; Saponins/chemistry ; Saponins/pharmacology ; Spirostans/pharmacology ; Steroids/chemistry ; Steroids/pharmacology ; Sterols/pharmacology ; Ultrafiltration
Czasopismo naukowe
Tytuł :
A methimazole resistant patient with Graves' disease (GD): A case report of mid-term management with herbal decoctions mainly composed of Anemarrhena Bunge.
Autorzy :
Kim J; Kyunghee-saeng Korean Medicine Clinic, Seoul, South Korea. Electronic address: .
Kim TH; Korean Medicine Clinical Trial Center, Korean Medicine Hospital, Kyung Hee University, Seoul, South Korea. Electronic address: .
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Źródło :
Complementary therapies in medicine [Complement Ther Med] 2018 Aug; Vol. 39, pp. 109-113. Date of Electronic Publication: 2018 Jun 12.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Anemarrhena*
Graves Disease/*drug therapy
Plant Extracts/*therapeutic use
Adult ; Drug Resistance ; Female ; Humans ; Methimazole/adverse effects ; Methimazole/therapeutic use
Czasopismo naukowe
Tytuł :
Optimization of extraction for Anemarrhena asphodeloides Bge. using silica gel-based vortex-homogenized matrix solid-phase dispersion and rapid identification of antioxidant substances.
Autorzy :
Ma T; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, Liaoning, P. R. China.
Sun J; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Li X; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Ma Y; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Liu L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Guo L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Liu Q; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
Sun Y; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang, P. R. China.
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Źródło :
Journal of separation science [J Sep Sci] 2020 Jun; Vol. 43 (11), pp. 2180-2192. Date of Electronic Publication: 2020 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Solid Phase Extraction*
Anemarrhena/*chemistry
Antioxidants/*analysis
Flavonoids/*analysis
Plant Extracts/*isolation & purification
Amidines/antagonists & inhibitors ; Amidines/pharmacology ; Animals ; Antioxidants/pharmacology ; Dose-Response Relationship, Drug ; Flavonoids/pharmacology ; Oxidative Stress/drug effects ; PC12 Cells ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Rats ; Silica Gel/chemistry
Czasopismo naukowe
Tytuł :
Anemarrhenae asphodeloides rhizoma Extract Enriched in Mangiferin Protects PC12 Cells against a Neurotoxic Agent-3-Nitropropionic Acid.
Autorzy :
Piwowar A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Rembiałkowska N; Department of Molecular and Cellular Biology, Wroclaw Medical University, 211A 50556 Borowska, Poland.
Rorbach-Dolata A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Garbiec A; Department of Developmental Biology, Institute of Experimental Biology, University of Wroclaw, ul. H. 21 50335 Sienkiewicza, Poland.
Ślusarczyk S; Department of Pharmaceutical Biology and Botany, Wroclaw Medical University, 211 50556 Borowska, Poland.
Dobosz A; Department of Basic Medical Sciences, Wroclaw Medical University, 211 50556 Borowska, Poland.
Długosz A; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Marchewka Z; Department of Toxicology, Wroclaw Medical University, 211 50556 Borowska, Poland.
Matkowski A; Department of Pharmaceutical Biology and Botany, Wroclaw Medical University, 211 50556 Borowska, Poland.
Saczko J; Department of Molecular and Cellular Biology, Wroclaw Medical University, 211A 50556 Borowska, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 04; Vol. 21 (7). Date of Electronic Publication: 2020 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Neuroprotective Agents/*pharmacology
Nitro Compounds/*adverse effects
PC12 Cells/*cytology
Propionates/*adverse effects
Xanthones/*pharmacology
Animals ; Apoptosis/drug effects ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacology ; Molecular Structure ; Neuroprotective Agents/chemistry ; PC12 Cells/drug effects ; Rats ; Rhizome/chemistry ; Time Factors ; Xanthones/chemistry
Czasopismo naukowe
Tytuł :
Comparison of α-glucosidase inhibitory effect and bioactive constituents of Anemarrhenae Rhizoma and Fibrous Roots.
Autorzy :
Nian SH; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Li HJ; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China.
Liu EH; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China. Electronic address: .
Li P; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing 210009, China. Electronic address: .
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2017 Oct 25; Vol. 145, pp. 195-202. Date of Electronic Publication: 2017 Jun 19.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anemarrhena*
Chromatography, High Pressure Liquid ; Humans ; Plant Roots ; Rhizome ; alpha-Glucosidases
Czasopismo naukowe
Tytuł :
Cardioprotective effects of timosaponin B-II isolated from Anemarrhena rhizome in a zebrafish model.
Autorzy :
Du MJ; Guangdong Pharmaceutical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangzhou, China.
Chen JP; The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, China.
Lian BW; Guangdong Pharmaceutical University, Guangzhou, China.
Mei WJ; Guangdong Pharmaceutical University, Guangzhou, China; Guangdong Province Engineering Technology Centre for Molecular Probe and Biomedicine Imaging, Guangzhou, China.
Yu JX; Jinan University, Guangzhou, China.
Chen LS; Guangdong Pharmaceutical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangzhou, China.
Deng SB; Guangdong Pharmaceutical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangzhou, China.
Zhong YM; Guangdong Pharmaceutical University, Guangzhou, China;, Email: .
Yu CQ; Guangdong Pharmaceutical University, Guangzhou, China; Guangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangzhou, China; Guangdong Engineering & Technology Research Center of topical precise drug delivery system; Guangzhou, China;, Email: .
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Źródło :
Die Pharmazie [Pharmazie] 2020 May 01; Vol. 75 (5), pp. 201-204.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemarrhena/*chemistry
Anti-Inflammatory Agents/*pharmacology
Cardiotonic Agents/*pharmacology
Saponins/*pharmacology
Steroids/*pharmacology
Animals ; Animals, Genetically Modified ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/isolation & purification ; Cardiotonic Agents/isolation & purification ; Cardiotonic Agents/toxicity ; Female ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Neutrophils/drug effects ; Neutrophils/metabolism ; Rhizome ; Saponins/isolation & purification ; Saponins/toxicity ; Steroids/isolation & purification ; Steroids/toxicity ; Zebrafish
Czasopismo naukowe
Tytuł :
Inhibitory effects of norlignans isolated from Anemarrhena asphodeloides on degranulation of rat basophilic leukemia- 2H3Cells.
Autorzy :
Bak JP; The Clinical Center for Bio-industry, Semyung University, Jecheon 390-711, South Korea.
Cho YM; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Kim I; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Park DW; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Kwon JE; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Jeong YJ; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Kwak JH; School of Pharmacy, Sungkyunkwan University, Suwon 440-746, South Korea. Electronic address: .
Kang SC; Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2016 Dec; Vol. 84, pp. 1061-1066. Date of Electronic Publication: 2016 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena*/chemistry
Anti-Allergic Agents/*pharmacology
Cell Degranulation/*drug effects
Leukemia, Basophilic, Acute/*pathology
Lignans/*pharmacology
Mast Cells/*drug effects
Plant Extracts/*pharmacology
Anaphylaxis/blood ; Anaphylaxis/chemically induced ; Anaphylaxis/prevention & control ; Animals ; Anti-Allergic Agents/isolation & purification ; Cell Line, Tumor ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Ethanol/chemistry ; Histamine/metabolism ; Leukemia, Basophilic, Acute/metabolism ; Lignans/isolation & purification ; Male ; Mast Cells/metabolism ; Mast Cells/pathology ; Mice ; Mice, Inbred C57BL ; Phytotherapy ; Plant Extracts/isolation & purification ; Plants, Medicinal ; Rats ; Rhizome ; Solvents/chemistry ; p-Methoxy-N-methylphenethylamine
Czasopismo naukowe
Tytuł :
Cytotoxic steroidal saponins from the rhizome of Anemarrhena asphodeloides.
Autorzy :
Zhao YF; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Zhou J; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Zhang MJ; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Zhang M; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Huang XF; Department of Natural Medicinal Chemistry, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: .
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Źródło :
Steroids [Steroids] 2020 Mar; Vol. 155, pp. 108557. Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemarrhena/*chemistry
Antineoplastic Agents, Phytogenic/*pharmacology
Rhizome/*chemistry
Saponins/*pharmacology
Steroids/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Models, Molecular ; Molecular Structure ; Saponins/chemistry ; Saponins/isolation & purification ; Steroids/chemistry ; Steroids/isolation & purification ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
A fructan from Anemarrhena asphodeloides Bunge showing neuroprotective and immunoregulatory effects.
Autorzy :
Zhang S; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Zhang Q; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
An L; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Zhang J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Li Z; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Zhang J; Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, People's Republic of China.
Li Y; School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.
Tuerhong M; College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, People's Republic of China.
Ohizumi Y; Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai 989-3201, Japan.
Jin J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Xu J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China. Electronic address: .
Guo Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, People's Republic of China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2020 Feb 01; Vol. 229, pp. 115477. Date of Electronic Publication: 2019 Oct 17.
Typ publikacji :
Journal Article
MeSH Terms :
Anemarrhena/*chemistry
Fructans/*pharmacology
Immunologic Factors/*pharmacology
Neuroprotective Agents/*pharmacology
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Fructans/chemistry ; Humans ; Immunologic Factors/chemistry ; Mice ; Monosaccharides/analysis ; Neuroprotective Agents/chemistry ; Phagocytosis/drug effects ; RAW 264.7 Cells ; Structure-Activity Relationship
Czasopismo naukowe

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