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Wyszukujesz frazę ""Angiogenesis"" wg kryterium: Temat


Tytuł :
A 60% Edible Ethanolic Extract of Ulmus davidiana Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis.
Autorzy :
Park J; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.
Kim HO; Department of Biotechnology and Bioengineering, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.; Biohealth-machinery Convergence Engineering, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.
Park KH; Department of Emergency Medical Rescue, Nambu University, Gwangju 62271, Korea.; Department of Emergency Medicine, Graduate School of Chonnam National University, Gwangju 61469, Korea.
Wie MB; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.
Choi SE; Department of Forest Biomaterials Engineering, Kangwon National University, Gangwon-do 24341, Korea.
Yun JH; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon-do 24341, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 03; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors*/chemistry
Angiogenesis Inhibitors*/pharmacology
Plant Extracts*/chemistry
Plant Extracts*/pharmacology
Human Umbilical Vein Endothelial Cells/*metabolism
Neovascularization, Pathologic/*drug therapy
Ulmus/*chemistry
Vascular Endothelial Growth Factor A/*antagonists & inhibitors
Ethanol/chemistry ; Human Umbilical Vein Endothelial Cells/pathology ; Humans ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; Vascular Endothelial Growth Factor A/pharmacology
Czasopismo naukowe
Tytuł :
An Insight into the Anti-Angiogenic and Anti-Metastatic Effects of Oridonin: Current Knowledge and Future Potential.
Autorzy :
Abdullah NA; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Md Hashim NF; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Ammar A; Wolfson Wohl Translational Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Bearsden, Glasgow City G61 1BD, UK.
Muhamad Zakuan N; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 03; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Angiogenesis Inhibitors*/chemistry
Angiogenesis Inhibitors*/therapeutic use
Antineoplastic Agents, Phytogenic*/chemistry
Antineoplastic Agents, Phytogenic*/therapeutic use
Diterpenes, Kaurane*/chemistry
Diterpenes, Kaurane*/therapeutic use
Neoplasms*/blood supply
Neoplasms*/drug therapy
Neoplasms*/metabolism
Isodon/*chemistry
Humans ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Evaluation of VEGF mediated pro-angiogenic and hemostatic effects and chemical marker investigation for Typhae Pollen and its processed product.
Autorzy :
Gao M; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Ge Z; The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210000, China. Electronic address: .
Deng R; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Bao B; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Yao W; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Cao Y; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Shan M; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Cheng F; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Yan H; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Chen P; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Zhang L; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113591. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Pollen*
Typhaceae*
Angiogenesis Inducing Agents/*pharmacology
Drugs, Chinese Herbal/*pharmacology
Hemostatics/*pharmacology
Vascular Endothelial Growth Factor A/*biosynthesis
Angiogenesis Inducing Agents/isolation & purification ; Animals ; Animals, Genetically Modified ; Biomarkers/metabolism ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical/methods ; Drugs, Chinese Herbal/isolation & purification ; Hemostatics/isolation & purification ; Vascular Endothelial Growth Factor A/genetics ; Zebrafish
Czasopismo naukowe
Tytuł :
Antiangiogenic Tyrosine Kinase Inhibitors in Metastatic Colorectal Cancer: Focusing on Regorafenib.
Autorzy :
Papadimitriou M; Oncology Unit, Second Department of Surgery, 'Aretaieion' University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece.
Papadimitriou CA; Oncology Unit, Second Department of Surgery, 'Aretaieion' University Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece .
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Źródło :
Anticancer research [Anticancer Res] 2021 Feb; Vol. 41 (2), pp. 567-582.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neovascularization, Pathologic*
Angiogenesis Inhibitors/*therapeutic use
Colorectal Neoplasms/*drug therapy
Phenylurea Compounds/*therapeutic use
Protein Kinase Inhibitors/*therapeutic use
Protein-Tyrosine Kinases/*antagonists & inhibitors
Pyridines/*therapeutic use
Angiogenesis Inhibitors/adverse effects ; Animals ; Colorectal Neoplasms/enzymology ; Colorectal Neoplasms/pathology ; Humans ; Molecular Targeted Therapy ; Neoplasm Metastasis ; Phenylurea Compounds/adverse effects ; Protein Kinase Inhibitors/adverse effects ; Protein-Tyrosine Kinases/metabolism ; Pyridines/adverse effects ; Signal Transduction ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The efficacy and toxicity of angiogenesis inhibitors for ovarian cancer: a meta-analysis of randomized controlled trials.
Autorzy :
Guo C; Department of Pharmacy, The First Hospital of China Medical University, Nanjing Street No. 155, Heping District, Shenyang City, 110001, Liaoning, China.; School of Pharmaceutical Science, China Medical University, Puhe Road No.77, Shenyang City, 110122, Liaoning, China.
Yan C; Department of Pharmacy, The First Hospital of China Medical University, Nanjing Street No. 155, Heping District, Shenyang City, 110001, Liaoning, China.; School of Pharmaceutical Science, China Medical University, Puhe Road No.77, Shenyang City, 110122, Liaoning, China.
Qu L; Department of Pharmacy, The First Hospital of China Medical University, Nanjing Street No. 155, Heping District, Shenyang City, 110001, Liaoning, China.; School of Pharmaceutical Science, China Medical University, Puhe Road No.77, Shenyang City, 110122, Liaoning, China.
Du R; Department of Pharmacy, The First Hospital of China Medical University, Nanjing Street No. 155, Heping District, Shenyang City, 110001, Liaoning, China.; School of Pharmaceutical Science, China Medical University, Puhe Road No.77, Shenyang City, 110122, Liaoning, China.
Lin J; Department of Pharmacy, The First Hospital of China Medical University, Nanjing Street No. 155, Heping District, Shenyang City, 110001, Liaoning, China. .; School of Pharmaceutical Science, China Medical University, Puhe Road No.77, Shenyang City, 110122, Liaoning, China. .
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Źródło :
Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2021 Feb; Vol. 303 (2), pp. 285-311. Date of Electronic Publication: 2020 Nov 21.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Randomized Controlled Trials as Topic*
Angiogenesis Inhibitors/*administration & dosage
Antineoplastic Agents/*administration & dosage
Carcinoma, Ovarian Epithelial/*drug therapy
Ovarian Neoplasms/*drug therapy
Angiogenesis Inhibitors/adverse effects ; Antineoplastic Agents/adverse effects ; Carcinoma, Ovarian Epithelial/mortality ; Disease-Free Survival ; Female ; Humans ; Neoplasm Recurrence, Local ; Ovarian Neoplasms/mortality ; Progression-Free Survival ; Survival Analysis
Czasopismo naukowe
Tytuł :
Local Bevacizumab Treatment of Juvenile-Onset Respiratory Papillomatosis Might Induce Multiple Tracheal Pyogenic Granulomas.
Autorzy :
Zeleník K; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
Komínek P; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
Staníková L; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
Formánek M; Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Ostrava, Ostrava, Czech Republic.
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Źródło :
The Laryngoscope [Laryngoscope] 2021 Feb; Vol. 131 (2), pp. E518-E520. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inhibitors/*adverse effects
Bevacizumab/*adverse effects
Granuloma, Pyogenic/*chemically induced
Papillomavirus Infections/*drug therapy
Respiratory Tract Infections/*drug therapy
Tracheal Diseases/*chemically induced
Administration, Mucosal ; Angiogenesis Inhibitors/administration & dosage ; Angiogenesis Inhibitors/therapeutic use ; Bevacizumab/administration & dosage ; Bevacizumab/therapeutic use ; Child, Preschool ; Female ; Humans ; Laryngoscopy
SCR Disease Name :
Recurrent respiratory papillomatosis
Czasopismo naukowe
Tytuł :
Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors.
Autorzy :
Chen JL; Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan.; Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; National Taiwan University Cancer Center, National Taiwan University College of Medicine, Taipei, Taiwan.
Pan CK; Department of Medical Research, National Taiwan University Hospital, No. 7, Chung-Shan S. Road, Taipei, 100, Taiwan.
Huang YS; Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan.
Tsai CY; Department of Medical Research, National Taiwan University Hospital, No. 7, Chung-Shan S. Road, Taipei, 100, Taiwan.; Institute of Toxicology, National Taiwan University College of Medicine, Taipei, Taiwan.
Wang CW; Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan.; Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.
Lin YL; Department of Medical Research, National Taiwan University Hospital, No. 7, Chung-Shan S. Road, Taipei, 100, Taiwan. .
Kuo SH; Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; National Taiwan University Cancer Center, National Taiwan University College of Medicine, Taipei, Taiwan.
Shieh MJ; Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2021 Feb; Vol. 70 (2), pp. 391-404. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Immunotherapy/*methods
Lung Neoplasms/*drug therapy
Lung Neoplasms/*radiotherapy
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Angiogenesis Inhibitors/pharmacology ; Animals ; Combined Modality Therapy ; Disease Models, Animal ; Humans ; Lung Neoplasms/pathology ; Mice
Czasopismo naukowe
Tytuł :
Comprehensive evaluation on anti-inflammatory and anti-angiogenic activities in vitro of fourteen flavonoids from Daphne Genkwa based on the combination of efficacy coefficient method and principal component analysis.
Autorzy :
Zhou DC; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China. Electronic address: .
Zheng G; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China. Electronic address: .
Jia LY; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China. Electronic address: .
He X; Tang Center of Herbal Medicine Research and Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL, 60637, USA. Electronic address: .
Zhang CF; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China; Tang Center of Herbal Medicine Research and Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL, 60637, USA. Electronic address: .
Wang CZ; Tang Center of Herbal Medicine Research and Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL, 60637, USA. Electronic address: .
Yuan CS; Tang Center of Herbal Medicine Research and Department of Anesthesia and Critical Care, University of Chicago, Chicago, IL, 60637, USA. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Mar 25; Vol. 268, pp. 113683. Date of Electronic Publication: 2020 Dec 08.
Typ publikacji :
Journal Article
MeSH Terms :
Daphne*
Angiogenesis Inhibitors/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Flavonoids/*pharmacology
Plant Extracts/*pharmacology
Principal Component Analysis/*methods
Angiogenesis Inhibitors/isolation & purification ; Animals ; Anti-Inflammatory Agents/isolation & purification ; Cell Survival/drug effects ; Cell Survival/physiology ; Drug Evaluation, Preclinical/methods ; Drug Therapy, Combination ; Flavonoids/isolation & purification ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Mice ; Plant Extracts/isolation & purification ; RAW 264.7 Cells ; Rats
Czasopismo naukowe
Tytuł :
Effects of the COVID-19 pandemic on neovascular age-related macular degeneration and response to delayed Anti-VEGF treatment.
Autorzy :
Yeter DY; Cumhuriyet University Faculty of Medicine, Department of Ophthalmology, Sivas 58140, Turkey. Electronic address: .
Dursun D; Cumhuriyet University Faculty of Medicine, Department of Ophthalmology, Sivas 58140, Turkey.
Bozali E; Cumhuriyet University Faculty of Medicine, Department of Ophthalmology, Sivas 58140, Turkey.
Ozec AV; Cumhuriyet University Faculty of Medicine, Department of Ophthalmology, Sivas 58140, Turkey.
Erdogan H; Cumhuriyet University Faculty of Medicine, Department of Ophthalmology, Sivas 58140, Turkey.
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Źródło :
Journal francais d'ophtalmologie [J Fr Ophtalmol] 2021 Mar; Vol. 44 (3), pp. 299-306. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article
MeSH Terms :
Macular Degeneration*/diagnosis
Macular Degeneration*/drug therapy
Macular Degeneration*/epidemiology
Macular Degeneration*/pathology
Pandemics*/statistics & numerical data
Retinal Neovascularization*/diagnosis
Retinal Neovascularization*/drug therapy
Retinal Neovascularization*/epidemiology
Retinal Neovascularization*/pathology
Time-to-Treatment*/statistics & numerical data
Angiogenesis Inhibitors/*therapeutic use
COVID-19/*epidemiology
Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/administration & dosage ; Delayed Diagnosis/statistics & numerical data ; Disease Progression ; Female ; Humans ; Intravitreal Injections ; Male ; Physical Examination/statistics & numerical data ; Prognosis ; Retrospective Studies ; SARS-CoV-2 ; Tomography, Optical Coherence ; Treatment Outcome ; Turkey/epidemiology ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/immunology
Czasopismo naukowe
Tytuł :
[Analysis of the "Portal" Care Model - Examination of the Outcome Quality of IVOM Therapy with Regard to Latency Periods in Exudative AMD].
Autorzy :
Rothaus K; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Farecki ML; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Mussinghoff P; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Faatz H; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Spital G; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Pauleikhoff D; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.
Lommatzsch AP; Retinologie, Augenzentrum am St. Franziskus-Hospital, Münster.; Retinologie, Universitätsaugenklinik Essen.
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Transliterated Title :
Analyse des Versorgungsmodells „Portal“ – Untersuchung der Ergebnisqualität der IVOM-Therapie im Hinblick auf Latenzzeiten bei exsudativer AMD.
Źródło :
Klinische Monatsblatter fur Augenheilkunde [Klin Monbl Augenheilkd] 2021 Mar; Vol. 238 (3), pp. 293-301. Date of Electronic Publication: 2019 Oct 25.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors*/therapeutic use
Tomography, Optical Coherence*
Follow-Up Studies ; Humans ; Intravitreal Injections ; Ranibizumab ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
[Intraocular inflammation with brolucizumab use : Patient management-diagnosis-therapy].
Autorzy :
Holz FG; Universitäts-Augenklinik Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Deutschland. .
Heinz C; Augenzentrum am St. Franziskus-Hospital Münster, Münster, Deutschland.; Klinik für Augenheilkunde, Universität Duisburg-Essen, Essen, Deutschland.
Wolf A; Klinik für Augenheilkunde am Universitätsklinikum Ulm, Ulm, Deutschland.
Hoerauf H; Augenklinik, Universitätsmedizin Göttingen, Göttingen, Deutschland.
Pleyer U; Klinik für Augenheilkunde, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Deutschland.
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Transliterated Title :
Intraokulare Entzündungen bei Brolucizumab-Anwendung : Patientenmanagement – Diagnose – Therapie.
Źródło :
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft [Ophthalmologe] 2021 Mar; Vol. 118 (3), pp. 248-256. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Clinical Trial Protocol; Journal Article; Review
MeSH Terms :
Angiogenesis Inhibitors*/therapeutic use
Receptors, Vascular Endothelial Growth Factor*
Antibodies, Monoclonal, Humanized ; Humans ; Inflammation/drug therapy ; Intravitreal Injections ; Randomized Controlled Trials as Topic ; Recombinant Fusion Proteins ; Visual Acuity
Czasopismo naukowe
Tytuł :
Single-shot bevacizumab for cerebral radiation injury.
Autorzy :
Voss M; Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany. .; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany. .; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany. .; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany. .
Wenger KJ; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany.; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany.; Institute of Neuroradiology, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.
Fokas E; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany.; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany.; Department of Radiotherapy and Oncology, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.
Forster MT; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany.; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany.; Department of Neurosurgery, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.
Steinbach JP; Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany.; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany.
Ronellenfitsch MW; Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Frankfurt/Main, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt/Main, Germany.; Frankfurt Cancer Institute (FCI), Georg-Speyer-Haus, Frankfurt/Main, Germany.
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Źródło :
BMC neurology [BMC Neurol] 2021 Feb 17; Vol. 21 (1), pp. 77. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*administration & dosage
Bevacizumab/*administration & dosage
Brain/*pathology
Brain Edema/*drug therapy
Brain Injuries/*drug therapy
Brain Neoplasms/*radiotherapy
Radiation Injuries/*drug therapy
Adult ; Aged ; Angiogenesis Inhibitors/therapeutic use ; Antibodies, Monoclonal/therapeutic use ; Bevacizumab/therapeutic use ; Brain Edema/diagnostic imaging ; Brain Edema/etiology ; Brain Injuries/diagnostic imaging ; Brain Injuries/etiology ; Brain Neoplasms/secondary ; Breast Neoplasms/pathology ; Dexamethasone/therapeutic use ; Dose-Response Relationship, Drug ; Female ; Glioma/radiotherapy ; Glucocorticoids/therapeutic use ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Necrosis ; Retrospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Retinal pigment epithelial characteristics in eyes with neovascular age-related macular degeneration : Long-term retinal changes under anti-vascular endothelial growth factor treatment.
Autorzy :
Ebner C; Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstraße 1, Pavillon 2a and 2b, 1130, Vienna, Austria.; Karl Landsteiner Institute for Process Optimization and Quality Management in Cataract Surgery, Wolkersbergenstraße 1, 1130, Vienna, Austria.
Wernigg C; Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstraße 1, Pavillon 2a and 2b, 1130, Vienna, Austria.; Karl Landsteiner Institute for Process Optimization and Quality Management in Cataract Surgery, Wolkersbergenstraße 1, 1130, Vienna, Austria.
Schütze C; Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstraße 1, Pavillon 2a and 2b, 1130, Vienna, Austria.; Karl Landsteiner Institute for Process Optimization and Quality Management in Cataract Surgery, Wolkersbergenstraße 1, 1130, Vienna, Austria.
Weingessel B; Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstraße 1, Pavillon 2a and 2b, 1130, Vienna, Austria.; Karl Landsteiner Institute for Process Optimization and Quality Management in Cataract Surgery, Wolkersbergenstraße 1, 1130, Vienna, Austria.
Vécsei-Marlovits PV; Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstraße 1, Pavillon 2a and 2b, 1130, Vienna, Austria. .; Karl Landsteiner Institute for Process Optimization and Quality Management in Cataract Surgery, Wolkersbergenstraße 1, 1130, Vienna, Austria. .
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Źródło :
Wiener klinische Wochenschrift [Wien Klin Wochenschr] 2021 Feb; Vol. 133 (3-4), pp. 123-130. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors*
Wet Macular Degeneration*/diagnosis
Wet Macular Degeneration*/drug therapy
Child ; Child, Preschool ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Intravitreal Injections ; Ranibizumab ; Retina ; Retinal Pigment Epithelium ; Retinal Pigments ; Retrospective Studies ; Tomography, Optical Coherence ; Vascular Endothelial Growth Factor A ; Visual Acuity
Czasopismo naukowe
Tytuł :
Cultivated Orostachys japonicus extract inhibits VEGF-induced angiogenesis via regulation of VEGFR2 signaling pathway in vitro and in vivo.
Autorzy :
Cho HD; Industry-Academy Cooperation, Dong-A University, Busan, 49315, Republic of Korea.
Lee KW; Department of Biotechnology, Dong-A University, Busan, 49315, Republic of Korea.
Won YS; Department of Biotechnology, Dong-A University, Busan, 49315, Republic of Korea.
Kim JH; Department of Food Science and Biotechnology, Kyungpook National University, Daegu, 41566, Republic of Korea.
Seo KI; Department of Biotechnology, Dong-A University, Busan, 49315, Republic of Korea. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2020 Jun 28; Vol. 256, pp. 112664. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Crassulaceae/*chemistry
Neovascularization, Pathologic/*drug therapy
Plant Extracts/*pharmacology
Signal Transduction/*drug effects
Vascular Endothelial Growth Factor A/*metabolism
Vascular Endothelial Growth Factor Receptor-2/*metabolism
Angiogenesis Inducing Agents/pharmacology ; Animals ; Cell Cycle Checkpoints/drug effects ; Cell Line ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Collagen/drug effects ; Collagen/metabolism ; Drug Combinations ; G1 Phase/drug effects ; Human Umbilical Vein Endothelial Cells ; Humans ; Laminin/drug effects ; Laminin/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neovascularization, Pathologic/metabolism ; Proteoglycans/drug effects ; Proteoglycans/metabolism ; Rats ; Rats, Sprague-Dawley ; Resting Phase, Cell Cycle/drug effects
Czasopismo naukowe
Tytuł :
Tocilizumab inhibits IL-8 and the proangiogenic potential of triple negative breast cancer cells.
Autorzy :
Alraouji NN; Department of Molecular Oncology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Aboussekhra A; Department of Molecular Oncology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2021 Jan; Vol. 60 (1), pp. 51-59. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Antibodies, Monoclonal, Humanized/*pharmacology
Antineoplastic Agents, Immunological/*pharmacology
Interleukin-8/*antagonists & inhibitors
Triple Negative Breast Neoplasms/*drug therapy
Angiogenesis Inhibitors/therapeutic use ; Animals ; Antineoplastic Agents, Immunological/therapeutic use ; Cell Line, Tumor ; Female ; Humans ; Interleukin-8/immunology ; Mice, Inbred NOD ; Mice, SCID ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/immunology ; Neovascularization, Pathologic/pathology ; Triple Negative Breast Neoplasms/blood supply ; Triple Negative Breast Neoplasms/immunology ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor.
Autorzy :
Shi J; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China.
Li J; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China; Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: .
Li J; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China.
Li R; Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region 999077, China.
Wu X; Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region 999077, China.
Gao F; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China.
Zou L; School of Medicine, Chengdu University, Chengdu, Sichuan 610106, China.
Mak WWS; Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region 999077, China.
Fu C; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China.
Zhang J; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China. Electronic address: .
Leung GP; Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jan; Vol. 81, pp. 153408. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Breast Neoplasms/*drug therapy
Angiogenesis Inhibitors/administration & dosage ; Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cardiotoxicity/etiology ; Cardiotoxicity/prevention & control ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Female ; Glycyrrhetinic Acid/administration & dosage ; Human Umbilical Vein Endothelial Cells ; Humans ; MCF-7 Cells ; Membrane Potential, Mitochondrial/drug effects ; Mice, Inbred BALB C ; Vascular Endothelial Growth Factor Receptor-2/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Ranibizumab treatment patterns in prior ranibizumab-treated neovascular age-related macular degeneration patients: Real-world outcomes from the LUMINOUS study.
Autorzy :
Holz FG; Department of Ophthalmology, University of Bonn, Bonn, Germany.
Minnella AM; Department of Ophthalmology, Catholic University of Sacred Heart-Foundation 'Policlinico Universitario A. Gemelli'-IRCCS, Rome, Italy.
Tuli R; The Retina Centre of Ottawa, Ottawa, Canada.; Department of Ophthalmology, University of Ottawa, Ottawa, Canada.
Yoganathan P; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Windsor Eye Associates, Windsor, Ontario, Canada.; Kresge Eye Institute, Wayne State University, Detroit, Michigan, United States of America.
Parikh S; Novartis Pharma AG, Basel, Switzerland.
Hamilton R; Department of Medical Retina, Moorfields Eye Hospital NHS Foundation Trust and National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Moorfields Eye Hospital, London, United Kingdom.
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Corporate Authors :
LUMINOUS™ study group
Źródło :
PloS one [PLoS One] 2020 Dec 30; Vol. 15 (12), pp. e0244183. Date of Electronic Publication: 2020 Dec 30 (Print Publication: 2020).
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Observational Study; Pragmatic Clinical Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Long Term Adverse Effects/*epidemiology
Macular Degeneration/*drug therapy
Ranibizumab/*therapeutic use
Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/administration & dosage ; Angiogenesis Inhibitors/adverse effects ; Drug Administration Schedule ; Female ; Humans ; Male ; Ranibizumab/administration & dosage ; Ranibizumab/adverse effects ; Visual Acuity
Czasopismo naukowe
Tytuł :
Bevacizumab Augments the Antitumor Efficacy of Infigratinib in Hepatocellular Carcinoma.
Autorzy :
Le TBU; Department of Haematology-Oncology, National University Health System, Singapore 119074, Singapore.
Vu TC; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore 169610, Singapore.
Ho RZW; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore 169610, Singapore.
Prawira A; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore 169610, Singapore.
Wang L; Department of Haematology-Oncology, National University Health System, Singapore 119074, Singapore.; Cancer Science Institute of Singapore, National University Hospital, Singapore 117599, Singapore.
Goh BC; Department of Haematology-Oncology, National University Health System, Singapore 119074, Singapore.; Cancer Science Institute of Singapore, National University Hospital, Singapore 117599, Singapore.
Huynh H; Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, National Cancer Centre, Singapore 169610, Singapore.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 10; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*therapeutic use
Antineoplastic Agents, Immunological/*therapeutic use
Bevacizumab/*therapeutic use
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
Phenylurea Compounds/*therapeutic use
Pyrimidines/*therapeutic use
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Angiogenesis Inhibitors/administration & dosage ; Animals ; Antineoplastic Agents, Immunological/administration & dosage ; Apoptosis ; Bevacizumab/administration & dosage ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Drug Synergism ; Extracellular Signal-Regulated MAP Kinases/genetics ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, SCID ; Neoplasm Metastasis ; Phenylurea Compounds/administration & dosage ; Pyrimidines/administration & dosage ; Ribosomal Protein S6 Kinases, 70-kDa/genetics ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Survivin/genetics ; Survivin/metabolism ; Tumor Hypoxia ; cdc25 Phosphatases/genetics ; cdc25 Phosphatases/metabolism
Czasopismo naukowe
Tytuł :
Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs.
Autorzy :
Peach ML; Basic Science Program, Chemical Biology Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD 21701, USA.
Beedie SL; Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.; School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Chau CH; Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Collins MK; Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Markolovic S; Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Luo W; Drug Design & Development Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Tweedie D; Drug Design & Development Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Steinebach C; Pharmaceutical Institute, University of Bonn, 53121 Bonn, Germany.
Greig NH; Drug Design & Development Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Gütschow M; Pharmaceutical Institute, University of Bonn, 53121 Bonn, Germany.
Vargesson N; School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Nicklaus MC; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD 21701, USA.
Figg WD; Molecular Pharmacology Section, Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Dec 02; Vol. 25 (23). Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Docking Simulation*
Adaptor Proteins, Signal Transducing/*metabolism
Angiogenesis Inhibitors/*pharmacology
Aorta/*drug effects
Neovascularization, Physiologic/*drug effects
Thalidomide/*analogs & derivatives
Thalidomide/*pharmacology
Ubiquitin-Protein Ligases/*metabolism
Angiogenesis Inhibitors/chemistry ; Animals ; Computer Simulation ; Humans ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe

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