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Wyszukujesz frazę ""Angiotensin II"" wg kryterium: Temat


Tytuł :
Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload.
Autorzy :
Zhang L; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Zhang B; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Yu Y; Department of General Practice, Zhongshan Hospital, Fudan University.
Wang J; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Wu J; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Su Y; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Jiang H; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Zou Y; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
Ge J; Department of Cardiology, Zhongshan Hospital, Fudan University.; Shanghai Institute of Cardiovascular Diseases.
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Źródło :
International heart journal [Int Heart J] 2021 Jan 30; Vol. 62 (1), pp. 162-170. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin II/*pharmacology
HMGB1 Protein/*drug effects
Losartan/*pharmacology
Myocardium/*metabolism
Angiotensin II Type 1 Receptor Blockers/administration & dosage ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Aorta/pathology ; Cardiomegaly/drug therapy ; Cardiomegaly/metabolism ; Case-Control Studies ; Constriction ; HMGB1 Protein/blood ; HMGB1 Protein/metabolism ; Imidazoles/administration & dosage ; Imidazoles/pharmacology ; Losartan/administration & dosage ; Male ; Mice ; Mice, Inbred C57BL ; Myocytes, Cardiac/drug effects ; Pyridines/administration & dosage ; Pyridines/pharmacology ; Up-Regulation ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose.
Autorzy :
Sha NN; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai, China.
Zhang JL; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Poon CC; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, China.
Li WX; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li Y; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang YF; National TCM Clinical Research Base of Hypertension, the affiliated Hospital of Shandong University of TCM, Jinan, China.
Shi W; National TCM Clinical Research Base of Hypertension, the affiliated Hospital of Shandong University of TCM, Jinan, China.
Lin FH; Department of Orthopaedic, Shenzhen Pingle Orthopaedic Hospital, Shenzhen, China.
Lin WP; Department of Orthopaedic, Shenzhen Pingle Orthopaedic Hospital, Shenzhen, China.
Wang YJ; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai, China.
Zhang Y; Spine Disease Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai, China.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2021 Jan 01; Vol. 320 (1), pp. E55-E70. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin I/*pharmacology
Angiotensin II/*pharmacology
Bone Density Conservation Agents/*pharmacology
Bone and Bones/*drug effects
Glucose/*adverse effects
Peptide Fragments/*pharmacology
3T3 Cells ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Bone Density/drug effects ; Bone Development/drug effects ; Male ; Mice ; Osteoblasts/drug effects ; Osteoclasts/drug effects ; Osteoporosis/prevention & control ; Phosphorylation/drug effects ; RAW 264.7 Cells ; Rats ; Rats, Inbred SHR
Czasopismo naukowe
Tytuł :
The effect of olmesartan on aortic intimal thickening after balloon injury through Apelin/APJ.
Autorzy :
Li Y; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China. Electronic address: .
Guo J; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Yu H; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Zhou J; Department of Emergency Medicine, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Chu X; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Hou B; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Ge J; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Li T; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Duan S; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Xu H; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
Yang X; Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province 266003,China.
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Źródło :
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology [Cardiovasc Pathol] 2020 Nov - Dec; Vol. 49, pp. 107230. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Neointima*
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Apelin/*metabolism
Apelin Receptors/*metabolism
Imidazoles/*pharmacology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Tetrazoles/*pharmacology
Vascular System Injuries/*drug therapy
Angioplasty, Balloon ; Angiotensin II/metabolism ; Animals ; Aorta/drug effects ; Aorta/injuries ; Aorta/metabolism ; Aorta/pathology ; Cell Proliferation/drug effects ; Constriction, Pathologic ; Disease Models, Animal ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Male ; Muscle, Smooth, Vascular/injuries ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Rats, Wistar ; Receptor, Angiotensin, Type 1/metabolism ; Signal Transduction ; Vascular System Injuries/etiology ; Vascular System Injuries/metabolism ; Vascular System Injuries/pathology
Czasopismo naukowe
Tytuł :
A pressor dose of angiotensin II has no influence on the angiotensin-converting enzyme 2 and other molecules associated with SARS-CoV-2 infection in mice.
Autorzy :
Wang Y; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Takeshita H; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Yamamoto K; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Huang Y; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Wang C; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Nakajima T; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Nozato Y; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Fujimoto T; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Yokoyama S; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Hongyo K; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Nakagami F; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Akasaka H; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Takami Y; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Takeya Y; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Sugimoto K; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Rakugi H; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Mar; Vol. 35 (3), pp. e21419.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*
Angiotensin II/*pharmacology
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*metabolism
Losartan/*pharmacology
ADAM17 Protein/genetics ; ADAM17 Protein/metabolism ; Angiotensin II/administration & dosage ; Angiotensin II Type 1 Receptor Blockers/administration & dosage ; Angiotensin-Converting Enzyme 2/genetics ; Animals ; Furin/genetics ; Furin/metabolism ; Gene Expression Regulation, Enzymologic/drug effects ; Losartan/administration & dosage ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Apelin-potential therapy for COVID-19?
Autorzy :
Saeedi Saravi SS; Center for Molecular Cardiology, University of Zurich, 8952 Schlieren, Switzerland; Department of Internal Medicine, Cantonal Hospital Baden, Baden, Switzerland.
Beer JH; Center for Molecular Cardiology, University of Zurich, 8952 Schlieren, Switzerland; Department of Internal Medicine, Cantonal Hospital Baden, Baden, Switzerland. Electronic address: .
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Źródło :
Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2020 Aug; Vol. 145, pp. 84-87. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin II Type 1 Receptor Blockers/*therapeutic use
Angiotensin-Converting Enzyme Inhibitors/*therapeutic use
Apelin/*therapeutic use
Apelin Receptors/*therapeutic use
Betacoronavirus/*metabolism
Coronavirus Infections/*drug therapy
Peptidyl-Dipeptidase A/*metabolism
Pneumonia, Viral/*drug therapy
Angiotensin I/metabolism ; Angiotensin II/biosynthesis ; Angiotensin II/blood ; Angiotensin-Converting Enzyme 2 ; Animals ; Apelin/metabolism ; Apelin Receptors/agonists ; Apelin Receptors/metabolism ; COVID-19 ; Coronavirus Infections/virology ; Drug Repositioning/methods ; Humans ; Mice ; Pandemics ; Peptide Fragments/metabolism ; Pneumonia, Viral/virology ; Receptor, Angiotensin, Type 1/metabolism ; Renin-Angiotensin System/drug effects ; Renin-Angiotensin System/immunology ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.
Autorzy :
Qi Y; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
Liang X; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
Dai F; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
Guan H; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
Sun J; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
Yao W; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, Jiangsu, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jul 29; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Actin Cytoskeleton/*drug effects
Angiotensin II/*pharmacology
Cell Dedifferentiation/*drug effects
Myocytes, Smooth Muscle/*drug effects
Receptor, Angiotensin, Type 1/*genetics
rho-Associated Kinases/*genetics
rhoA GTP-Binding Protein/*genetics
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/analogs & derivatives ; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/pharmacology ; Actin Cytoskeleton/genetics ; Actin Cytoskeleton/metabolism ; Actins/genetics ; Actins/metabolism ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Cell Line ; Cell Movement/drug effects ; Gene Expression Regulation ; Humans ; Irbesartan/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/metabolism ; Polymerization/drug effects ; Protein Kinase Inhibitors/pharmacology ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Receptor, Angiotensin, Type 1/metabolism ; Signal Transduction ; Vasodilator Agents/pharmacology ; rho-Associated Kinases/metabolism ; rhoA GTP-Binding Protein/antagonists & inhibitors ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Tytuł :
Tranilast prevents doxorubicin-induced myocardial hypertrophy and angiotensin II synthesis in rats.
Autorzy :
Zhan C; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Bai N; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Zheng M; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Wang Y; Department of Digestion, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang 453000, China.
Wang Y; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Zhang L; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li J; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li G; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Zhao H; Department of Cardiology, The People's Hospital of Liaoning Province, Shenyang 110015, China.
Liu G; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Lou Q; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Yang W; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li T; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li L; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Li W; Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Feb 15; Vol. 267, pp. 118984. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin II/*drug effects
Cardiomegaly/*metabolism
Doxorubicin/*adverse effects
ortho-Aminobenzoates/*pharmacology
Angiotensin II/biosynthesis ; Angiotensin II/metabolism ; Animals ; Antioxidants/pharmacology ; Cardiomegaly/drug therapy ; Doxorubicin/pharmacology ; Fibrosis ; Heart Diseases/etiology ; Male ; Mast Cells/drug effects ; Myocardium/metabolism ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar ; ortho-Aminobenzoates/metabolism
Czasopismo naukowe
Tytuł :
The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication: possible treatment options related to the renin-angiotensin system.
Autorzy :
Offringa A; Microbiology and System Biology, Netherlands Organisation for Applied Scientific Research, The Hague, The Netherlands.
Montijn R; Microbiology and System Biology, Netherlands Organisation for Applied Scientific Research, The Hague, The Netherlands.
Singh S; Vascular Medicine, Amsterdam UMC, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.; Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
Paul M; Faculty of Health Medicine and Life Sciences, University of Maastricht, Maastricht, The Netherlands.
Pinto YM; Cardiology, Amsterdam UMC, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
Pinto-Sietsma SJ; Vascular Medicine, Amsterdam UMC, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.; Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.
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Źródło :
European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2020 Sep 01; Vol. 6 (5), pp. 317-325.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Angiotensin II Type 1 Receptor Blockers/*therapeutic use
Antiviral Agents/*therapeutic use
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Peptidyl-Dipeptidase A/*metabolism
Pneumonia, Viral/*drug therapy
Renin-Angiotensin System/*drug effects
Virus Internalization/*drug effects
Angiotensin II/metabolism ; Animals ; Betacoronavirus/immunology ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/metabolism ; Coronavirus Infections/virology ; Endocytosis/drug effects ; Host-Pathogen Interactions ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/therapeutic use ; Pneumonia, Viral/immunology ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/virology ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Increased angiotensin II from adipose tissue modulates myocardial collagen I and III in obese rats.
Autorzy :
da Silva-Bertani DCT; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Vileigas DF; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Mota GAF; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
de Souza SLB; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Sant'Ana PG; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Freire PP; Department of Morphology, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618970, Brazil.
de Tomasi LC; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Corrêa CR; Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil.
Padovani CR; Department of Biostatistics, Institute of Biosciences, São Paulo State University (UNESP), Botucatu, São Paulo 18618970, Brazil.
Fernandes T; Laboratory of Biochemistry and Molecular Biology of the Exercise, School of Physical Education and Sport, University of São Paulo (USP), 05508-900 São Paulo, Brazil.
de Oliveira EM; Laboratory of Biochemistry and Molecular Biology of the Exercise, School of Physical Education and Sport, University of São Paulo (USP), 05508-900 São Paulo, Brazil.
Cicogna AC; Department of Internal Medicine, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, São Paulo 18618687, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Jul 01; Vol. 252, pp. 117650. Date of Electronic Publication: 2020 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue/*metabolism
Angiotensin II/*metabolism
Myocardium/*pathology
Obesity/*physiopathology
Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Collagen Type I/metabolism ; Collagen Type III/metabolism ; Diet, High-Fat/adverse effects ; Fibrosis ; Losartan/pharmacology ; Male ; Myocardium/metabolism ; Rats ; Rats, Wistar ; Renin-Angiotensin System/physiology
Czasopismo naukowe
Tytuł :
Might renin-angiotensin system blockers play a role in the COVID-19 pandemic?
Autorzy :
Battistoni A; Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome.
Volpe M; Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sapienza University of Rome.; IRCCS Neuromed, Pozzilli, Italy.
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Źródło :
European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2020 Jul 01; Vol. 6 (4), pp. 248-251.
Typ publikacji :
Editorial
MeSH Terms :
Renin-Angiotensin System*
Acute Lung Injury/*metabolism
Angiotensin II Type 1 Receptor Blockers/*therapeutic use
Angiotensin-Converting Enzyme Inhibitors/*therapeutic use
Betacoronavirus/*metabolism
Coronavirus Infections/*metabolism
Hypertension/*drug therapy
Peptidyl-Dipeptidase A/*metabolism
Pneumonia, Viral/*metabolism
Acute Lung Injury/etiology ; Angiotensin II/metabolism ; Angiotensin-Converting Enzyme 2 ; COVID-19 ; Coronavirus Infections/complications ; Humans ; Hypertension/complications ; Pandemics ; Pneumonia, Viral/complications ; Receptor, Angiotensin, Type 1/metabolism ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/metabolism ; Up-Regulation
Opinia redakcyjna
Tytuł :
Alteration of the Renin-Angiotensin-Aldosterone System in Shock: Role of the Dipeptidyl Peptidase 3.
Autorzy :
Picod A; INSERM U942 MASCOT Paris, France and.; University of Paris Paris, France.
Deniau B; INSERM U942 MASCOT Paris, France and.; University of Paris Paris, France.
Vaittinada Ayar P; INSERM U942 MASCOT Paris, France and.; University of Paris Paris, France.
Genest M; INSERM U942 MASCOT Paris, France and.
Julian N; INSERM U942 MASCOT Paris, France and.; University of Paris Paris, France.
Azibani F; INSERM U942 MASCOT Paris, France and.
Mebazaa A; INSERM U942 MASCOT Paris, France and.; University of Paris Paris, France.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 15; Vol. 203 (4), pp. 526-527.
Typ publikacji :
Letter; Comment
MeSH Terms :
Angiotensin II*
Renin*
Catecholamines ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Humans ; Renin-Angiotensin System
Opinia redakcyjna
Tytuł :
Reply to Picod et al. : Alteration of the Renin-Angiotensin-Aldosterone System in Shock: Role of the Dipeptidyl Peptidase 3.
Autorzy :
Chawla LS; Veterans Affairs Medical Center San Diego, California and.
Bellomo R; The University of Melbourne Melbourne, Victoria, Australia.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Feb 15; Vol. 203 (4), pp. 527-528.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Angiotensin II*
Renin*
Catecholamines ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Humans ; Renin-Angiotensin System
Raport
Tytuł :
The pivotal role of the angiotensin-II-NF-κB axis in the development of COVID-19 pathophysiology.
Autorzy :
Okamoto H; Minami-Otsuka Institute of Technology, Minami-Otsuka Clinic, Tokyo, Japan. .
Ichikawa N; Minami-Otsuka Institute of Technology, Minami-Otsuka Clinic, Tokyo, Japan.
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Źródło :
Hypertension research : official journal of the Japanese Society of Hypertension [Hypertens Res] 2021 Jan; Vol. 44 (1), pp. 126-128. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Editorial
MeSH Terms :
Angiotensin II*
NF-kappa B*
Signal Transduction*
COVID-19/*physiopathology
Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; COVID-19/drug therapy ; Humans ; I-kappa B Proteins
Opinia redakcyjna
Tytuł :
Monosomy X in Female Mice Influences the Regional Formation and Augments the Severity of Angiotensin II-Induced Aortopathies.
Autorzy :
AlSiraj Y; Department of Pharmacology and Nutritional Sciences (Y.A., S.E.T., E.B., L.A.C.), University of Kentucky, Lexington.
Thatcher SE; Department of Pharmacology and Nutritional Sciences (Y.A., S.E.T., E.B., L.A.C.), University of Kentucky, Lexington.
Blalock E; Department of Pharmacology and Nutritional Sciences (Y.A., S.E.T., E.B., L.A.C.), University of Kentucky, Lexington.
Saintilnord WN; Department of Molecular and Cellular Biochemistry (W.N.S.), University of Kentucky, Lexington.
Daugherty A; Department of Physiology (A.D., H.S.L.), University of Kentucky, Lexington.; Saha Cardiovascular Research Center (A.D., H.S.L.), University of Kentucky, Lexington.
Lu HS; Department of Physiology (A.D., H.S.L.), University of Kentucky, Lexington.; Saha Cardiovascular Research Center (A.D., H.S.L.), University of Kentucky, Lexington.
Luo W; Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, and Department of Cardiovascular Surgery, Texas Heart Institute, Houston (W.L., Y.H.S., S.A.L.).
Shen YH; Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, and Department of Cardiovascular Surgery, Texas Heart Institute, Houston (W.L., Y.H.S., S.A.L.).
LeMaire SA; Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, and Department of Cardiovascular Surgery, Texas Heart Institute, Houston (W.L., Y.H.S., S.A.L.).
Arnold AP; Integrative Biology and Physiology, University of California, Los Angeles (A.P.A.).
Cassis LA; Department of Pharmacology and Nutritional Sciences (Y.A., S.E.T., E.B., L.A.C.), University of Kentucky, Lexington.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jan; Vol. 41 (1), pp. 269-283. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II*
Aorta, Abdominal/*pathology
Aorta, Thoracic/*pathology
Aortic Aneurysm, Abdominal/*chemically induced
Aortic Aneurysm, Thoracic/*chemically induced
Turner Syndrome/*complications
Animals ; Aorta, Abdominal/metabolism ; Aorta, Thoracic/metabolism ; Aortic Aneurysm, Abdominal/genetics ; Aortic Aneurysm, Abdominal/metabolism ; Aortic Aneurysm, Abdominal/pathology ; Aortic Aneurysm, Thoracic/genetics ; Aortic Aneurysm, Thoracic/metabolism ; Aortic Aneurysm, Thoracic/pathology ; DNA Methylation ; Disease Models, Animal ; Female ; Histone Demethylases/genetics ; Histone Demethylases/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Ovariectomy ; Receptors, LDL/deficiency ; Receptors, LDL/genetics ; Severity of Illness Index ; Turner Syndrome/genetics
Czasopismo naukowe
Tytuł :
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation.
Autorzy :
Qiu Y; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Zheng F; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Ye C; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Chen AD; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Wang JJ; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China.
Chen Q; Department of Pathophysiology, Nanjing Medical University, Nanjing, 211166, China.
Li YH; Department of Pathophysiology, Nanjing Medical University, Nanjing, 211166, China.
Kang YM; Department of Physiology and Pathophysiology, Cardiovascular Research Center, Xi'an Jiaotong University School of Medicine, Xi'an, 710061, China.
Zhu GQ; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center of Translational Medicine for Cardiovascular Disease, and Department of Physiology, Nanjing Medical University, Nanjing, 211166, China. .; Department of Pathophysiology, Nanjing Medical University, Nanjing, 211166, China. .
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Źródło :
Neuroscience bulletin [Neurosci Bull] 2020 May; Vol. 36 (5), pp. 463-474. Date of Electronic Publication: 2020 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Capsaicin/*pharmacology
Kidney/*drug effects
Paraventricular Hypothalamic Nucleus/*metabolism
Reflex/*drug effects
Superoxides/*metabolism
6-Cyano-7-nitroquinoxaline-2,3-dione/pharmacology ; Acetophenones/pharmacology ; Acetylcysteine/pharmacology ; Allopurinol/pharmacology ; Angiotensin II/pharmacology ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Animals ; Blood Pressure/physiology ; Captopril/pharmacology ; Ditiocarb/pharmacology ; Kidney/innervation ; Kidney/physiology ; Losartan/pharmacology ; Male ; NADPH Oxidases/antagonists & inhibitors ; Onium Compounds/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptor, Angiotensin, Type 1 ; Reflex/physiology
Czasopismo naukowe
Tytuł :
The Other Angiotensin II Receptor: AT 2 R as a Therapeutic Target.
Autorzy :
Juillerat-Jeanneret L; Transplantation Center, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Chemin des Boveresses 155, CH1011 Lausanne, Switzerland.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Mar 12; Vol. 63 (5), pp. 1978-1995. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Angiotensin II Type 2 Receptor Blockers/*administration & dosage
Angiotensin II Type 2 Receptor Blockers/*metabolism
Drug Delivery Systems/*trends
Receptor, Angiotensin, Type 2/*metabolism
Angiotensin II Type 1 Receptor Blockers/administration & dosage ; Angiotensin II Type 1 Receptor Blockers/chemistry ; Angiotensin II Type 1 Receptor Blockers/metabolism ; Angiotensin II Type 2 Receptor Blockers/chemistry ; Animals ; Drug Delivery Systems/methods ; Humans ; Receptor, Angiotensin, Type 1/metabolism ; Renin-Angiotensin System/drug effects ; Renin-Angiotensin System/physiology
Czasopismo naukowe
Tytuł :
Pathogenic role of angiotensin II and the NF-κB system in a model of malignant hypertensive nephrosclerosis.
Autorzy :
Ávila VF; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
Foresto-Neto O; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
Arias SCA; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
Faustino VD; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
Malheiros DMAC; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
Camara NOS; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.; Laboratory of Transplantation Immunobiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Zatz R; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil. .
Fujihara CK; Renal Division, Department of Clinical Medicine, Faculty of Medicine, University of São Paulo São Paulo, São Paulo, Brazil.
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Źródło :
Hypertension research : official journal of the Japanese Society of Hypertension [Hypertens Res] 2019 Jun; Vol. 42 (6), pp. 779-789. Date of Electronic Publication: 2019 Feb 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II*
NF-kappa B*/antagonists & inhibitors
Hypertension, Renal/*pathology
Nephritis/*pathology
Nephrosclerosis/*pathology
Albuminuria/complications ; Angiotensin II Type 1 Receptor Blockers/therapeutic use ; Animals ; Arterioles/pathology ; Female ; Glomerulosclerosis, Focal Segmental/complications ; Kidney Cortex/pathology ; Kidney Glomerulus/pathology ; Lactation ; Losartan/therapeutic use ; Male ; Nephrectomy ; Pyrrolidines/pharmacology ; Rats ; Rats, Wistar ; Thiocarbamates/pharmacology
SCR Disease Name :
Hypertensive Nephropathy
Czasopismo naukowe
Tytuł :
[Risk of severe COVID-19 in hypertensive patients treated with renin-angiotensin-aldosterone system inhibitors].
Autorzy :
Golpe R; Servicio de Neumología, Hospital Universitario Lucus Augusti, Lugo, Spain. Electronic address: .
Pérez-de-Llano LA; Servicio de Neumología, Hospital Universitario Lucus Augusti, Lugo, Spain.
Dacal D; Servicio de Neumología, Hospital Universitario Lucus Augusti, Lugo, Spain.
Guerrero-Sande H; Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, Spain.
Pombo-Vide B; Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, Spain.
Ventura-Valcárcel P; Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, Spain.
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Transliterated Title :
Riesgo de COVID-19 grave en pacientes hipertensos tratados con inhibidores del sistema renina-angiotensina-aldosterona.
Corporate Authors :
Lugo Covid-19 team
Źródło :
Medicina clinica [Med Clin (Barc)] 2020 Dec 11; Vol. 155 (11), pp. 488-490. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
SARS-CoV-2*
Angiotensin II Type 1 Receptor Blockers/*adverse effects
COVID-19/*epidemiology
Hypertension/*drug therapy
Age Factors ; Aged ; Angiotensin II Type 1 Receptor Blockers/therapeutic use ; Cardiomyopathies/complications ; Diabetes Complications ; Female ; Hospitalization ; Humans ; Male ; Multivariate Analysis ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Design and optimization of candesartan loaded self-nanoemulsifying drug delivery system for improving its dissolution rate and pharmacodynamic potential.
Autorzy :
Verma R; Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.
Kaushik D; Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.
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Źródło :
Drug delivery [Drug Deliv] 2020 Dec; Vol. 27 (1), pp. 756-771.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Angiotensin II Type 1 Receptor Blockers/*administration & dosage
Benzimidazoles/*administration & dosage
Blood Pressure/*drug effects
Drug Delivery Systems/*methods
Tetrazoles/*administration & dosage
Angiotensin II Type 1 Receptor Blockers/chemistry ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Animals ; Benzimidazoles/chemistry ; Benzimidazoles/pharmacology ; Biological Availability ; Dose-Response Relationship, Drug ; Drug Carriers/chemistry ; Drug Liberation ; Drug Stability ; Emulsions ; Excipients/chemistry ; Food-Drug Interactions ; Male ; Rats, Wistar ; Solubility ; Tetrazoles/chemistry ; Tetrazoles/pharmacology
Czasopismo naukowe
Tytuł :
Determinants of renal oxygen metabolism during low Na diet: effect of angiotensin II AT 1 and aldosterone receptor blockade.
Autorzy :
Patinha D; Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, UK.; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Carvalho C; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Persson P; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Pihl L; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Fasching A; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Friederich-Persson M; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
O'Neill J; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
Palm F; Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden.
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Źródło :
The Journal of physiology [J Physiol] 2020 Dec; Vol. 598 (23), pp. 5573-5587. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II*/metabolism
Receptors, Mineralocorticoid*
Aldosterone/metabolism ; Animals ; Blood Pressure ; Diet ; Kidney/metabolism ; Male ; Oxygen/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptor, Angiotensin, Type 1/metabolism ; Renin-Angiotensin System
Czasopismo naukowe

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