- Tytuł :
-
Repositioning of histamine H
1 receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2. - Autorzy :
- Źródło :
- European journal of pharmacology [Eur J Pharmacol] 2021 Apr 05; Vol. 896, pp. 173897. Date of Electronic Publication: 2021 Jan 23.
- Typ publikacji :
- Journal Article
- MeSH Terms :
-
Angiotensin -Converting Enzyme 2 */antagonists & inhibitorsAngiotensin -Converting Enzyme 2 */metabolism
COVID-19*/drug therapy
COVID-19*/metabolism
SARS-CoV-2 */drug effects
SARS-CoV-2 */physiology
Doxepin/*pharmacology
Protein Binding/*drug effects
Virus Internalization/*drug effects
Antiviral Agents/pharmacology ; Drug Repositioning ; HEK293 Cells ; Histamine H1 Antagonists/classification ; Histamine H1 Antagonists/pharmacology ; Humans ; Spike Glycoprotein, Coronavirus/metabolism -
Czasopismo naukowe