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Wyszukujesz frazę ""Animals, Genetically Modified"" wg kryterium: Temat


Tytuł :
P25 Gene Knockout Contributes to Human Epidermal Growth Factor Production in Transgenic Silkworms.
Autorzy :
Wu M; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Ruan J; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Ye X; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Zhao S; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Tang X; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Wang X; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Li H; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
Zhong B; College of Animal Science, Zhejiang University, Hangzhou 310058, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 08; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 08.
Typ publikacji :
Journal Article
MeSH Terms :
Animals, Genetically Modified*/genetics
Animals, Genetically Modified*/metabolism
Bombyx*/genetics
Bombyx*/metabolism
Epidermal Growth Factor*/biosynthesis
Epidermal Growth Factor*/genetics
Gene Knockdown Techniques*
Fibroins/*genetics
Animals ; Humans ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
Secretory expression of thyroid hormone receptor using transgenic silkworms and its DNA binding activity.
Autorzy :
Nakaya H; Faculty of Science and Technology, Division of Molecular Science, Gunma University, Kiryu, Gunma, 376-8515, Japan.
Tatematsu KI; Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan.
Sezutsu H; Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, 305-8634, Japan.
Kuwabara N; Gunma Sericultural Technology Center, Maebashi, Gunma, 371-8570, Japan.
Koibuchi N; Department of Integrative Physiology, Graduate School of Medicine, Gunma University, 3-39-22 Showa-machi Maebashi, Gunma, 371-8511, Japan.
Takeda S; Faculty of Science and Technology, Division of Molecular Science, Gunma University, Kiryu, Gunma, 376-8515, Japan. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2020 Dec; Vol. 176, pp. 105723. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*/genetics
Animals, Genetically Modified*/metabolism
Bombyx*/genetics
Bombyx*/metabolism
Thyroid Hormone Receptors beta*/biosynthesis
Thyroid Hormone Receptors beta*/chemistry
Thyroid Hormone Receptors beta*/genetics
Thyroid Hormone Receptors beta*/isolation & purification
Animals ; DNA/chemistry ; DNA/metabolism ; Mice ; Protein Binding
Czasopismo naukowe
Tytuł :
Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1.
Autorzy :
Osum SH; Masonic Cancer Center, Department of Pediatrics, Division of Hematology and Oncology, University of Minnesota, Minneapolis, MN 55455, USA.
Watson AL; Recombinetics, Inc., Eagan, MN 55121, USA.
Largaespada DA; Masonic Cancer Center, Department of Pediatrics, Division of Hematology and Oncology, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 16; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Animals, Genetically Modified*
Disease Models, Animal*
Mutation Accumulation*
Genetic Engineering/*methods
Neurofibromatosis 1/*genetics
Animals ; Cattle ; Dogs ; Humans ; Mice ; Molecular Targeted Therapy/methods ; Neurofibromatosis 1/drug therapy ; Swine/genetics
Czasopismo naukowe
Tytuł :
Joint FAO/IAEA coordinated research project on "comparing rearing efficiency and competitiveness of sterile male strains produced by genetic, transgenic or symbiont-based technologies".
Autorzy :
Bourtzis K; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria. .
Cáceres C; Insect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, Austria.
Schetelig MF; Justus-Liebig-University Giessen, Institute for Insect Biotechnology, Insect Biotechnology in Plant Protection, Winchesterstr. 2, 35394, Giessen, Germany.
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Źródło :
BMC genetics [BMC Genet] 2020 Dec 18; Vol. 21 (Suppl 2), pp. 148. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Editorial; Introductory Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*
Insect Control*
Symbiosis*
Diptera/*genetics
Infertility, Male/*genetics
Animals ; Male
Czasopismo naukowe
Tytuł :
Axon Injury-Induced Autophagy Activation Is Impaired in a C. elegans Model of Tauopathy.
Autorzy :
Ko SH; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Gonzalez G; Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Liu Z; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Chen L; Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 13; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Animals, Genetically Modified*/genetics
Animals, Genetically Modified*/metabolism
Autophagy*
Axons*/metabolism
Axons*/pathology
Caenorhabditis elegans*/genetics
Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Microtubule-Associated Proteins*/genetics
Microtubule-Associated Proteins*/metabolism
Animals ; Disease Models, Animal ; Humans ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos.
Autorzy :
Schmidt JK; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Strelchenko N; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Park MA; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Kim YH; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Mean KD; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Schotzko ML; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Kang HJ; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Golos TG; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA. .; Department of Comparative Biosciences, Wisconsin National Primate Research Center, University of Wisconsin-Madison, 1220 Capitol Court, Madison, WI, 53715, USA. .; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, USA. .
Slukvin II; Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, USA. .; Department of Pathology and Laboratory Medicine, Wisconsin National Primate Research Center, University of Wisconsin-Madison, 1220 Capitol Court, Madison, WI, 53715, USA. .; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 28; Vol. 10 (1), pp. 18457. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Animals, Genetically Modified*/embryology
Animals, Genetically Modified*/genetics
CRISPR-Cas Systems*
Gene Editing*
Receptors, CCR5*/genetics
Receptors, CCR5*/metabolism
Embryo, Mammalian/*metabolism
Animals ; Macaca fascicularis
Czasopismo naukowe
Tytuł :
An optimized QF-binary expression system for use in zebrafish.
Autorzy :
Burgess J; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada.
Burrows JT; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada.
Sadhak R; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Chiang S; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Weiss A; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada.
D'Amata C; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada.
Molinaro AM; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Zhu S; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada.
Long M; The Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, ON, M5S 3E1, Canada.
Hu C; The Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, ON, M5S 3E1, Canada.
Krause HM; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; The Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, ON, M5S 3E1, Canada.
Pearson BJ; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, ON, M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Ontario Institute for Cancer Research, Toronto, ON, Canada. Electronic address: .
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Źródło :
Developmental biology [Dev Biol] 2020 Sep 15; Vol. 465 (2), pp. 144-156. Date of Electronic Publication: 2020 Jul 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*/genetics
Animals, Genetically Modified*/metabolism
Gene Expression*
Protozoan Proteins*/genetics
Protozoan Proteins*/metabolism
Transcription Factors*/genetics
Transcription Factors*/metabolism
Zebrafish*/genetics
Zebrafish*/metabolism
Neurospora crassa/*genetics
Animals
Czasopismo naukowe
Tytuł :
Mitochondrial Ca Dynamics in MCU Knockout C. elegans Worms.
Autorzy :
Álvarez-Illera P; Institute of Biology and Molecular Genetics (IBGM), Department of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, University of Valladolid and CSIC, Ramón y Cajal, 7, E-47005 Valladolid, Spain.
García-Casas P; Institute of Biology and Molecular Genetics (IBGM), Department of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, University of Valladolid and CSIC, Ramón y Cajal, 7, E-47005 Valladolid, Spain.
Fonteriz RI; Institute of Biology and Molecular Genetics (IBGM), Department of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, University of Valladolid and CSIC, Ramón y Cajal, 7, E-47005 Valladolid, Spain.
Montero M; Institute of Biology and Molecular Genetics (IBGM), Department of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, University of Valladolid and CSIC, Ramón y Cajal, 7, E-47005 Valladolid, Spain.
Alvarez J; Institute of Biology and Molecular Genetics (IBGM), Department of Biochemistry and Molecular Biology and Physiology, Faculty of Medicine, University of Valladolid and CSIC, Ramón y Cajal, 7, E-47005 Valladolid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 16; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Signaling*
Animals, Genetically Modified/*metabolism
Caenorhabditis elegans/*metabolism
Calcium/*metabolism
Mitochondria/*metabolism
Mitochondrial Membrane Transport Proteins/*deficiency
Animals ; Animals, Genetically Modified/genetics ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/metabolism ; Mitochondria/genetics ; Mitochondrial Membrane Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Simple transport and cryopreservation of cold-stored mouse embryos.
Autorzy :
Mukunoki A; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Takeo T; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Nakao S; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Tamura K; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Horikoshi Y; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
Nakagata N; Division of Reproductive Biotechnology and Innovation, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Kumamoto 860-0811, Japan.
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Źródło :
Experimental animals [Exp Anim] 2020 Nov 12; Vol. 69 (4), pp. 423-429. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Animals, Genetically Modified*
Embryo, Mammalian*
Cryopreservation/*methods
Embryo Transfer/*methods
Mice/*embryology
Specimen Handling/*methods
Transportation/*methods
Animals ; Vitrification
Czasopismo naukowe
Tytuł :
Revealing Alteration in the Hepatic Glucose Metabolism of Genetically Improved Carp, Jayanti Rohu Labeo rohita Fed a High Carbohydrate Diet Using Transcriptome Sequencing.
Autorzy :
Rasal KD; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Iquebal MA; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Dixit S; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Vasam M; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Raza M; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Sahoo L; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Jaiswal S; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Nandi S; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Mahapatra KD; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Rasal A; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Udit UK; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Meher PK; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Murmu K; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
Angadi UB; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Rai A; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Kumar D; Centre for Agricultural Bioinformatics (CABin), ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Sundaray JK; Fish Genetics and Biotechnology Division, ICAR-Central Institute of Freshwater Aquaculture, Bhubaneswar 751 002, India.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 31; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Animals, Genetically Modified/*metabolism
Carps/*metabolism
Diet, Carbohydrate Loading/*adverse effects
Liver/*metabolism
Sequence Analysis, RNA/*methods
Animals ; Animals, Genetically Modified/genetics ; Aquaculture/methods ; Carbohydrate Metabolism ; Carps/genetics ; Gene Expression Regulation ; Liver/pathology ; Signal Transduction ; Transcriptome
Czasopismo naukowe
Tytuł :
P130Cas/bcar1 mediates zebrafish caudal vein plexus angiogenesis.
Autorzy :
Wisniewski L; Division of Medicine, University College London, 5 University Street, London, WC1E 6JF, UK. .; Queen Mary University of London, London, EC1M 6BQ, UK. .
French V; Institute of Cardiovascular Science, University College London, 5 University Street, London, WC1E 6JF, UK.
Lockwood N; Division of Medicine, University College London, 5 University Street, London, WC1E 6JF, UK.; The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Valdivia LE; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.
Frankel P; Institute of Cardiovascular Science, University College London, 5 University Street, London, WC1E 6JF, UK. .
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 24; Vol. 10 (1), pp. 15589. Date of Electronic Publication: 2020 Sep 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neovascularization, Physiologic*
Animals, Genetically Modified/*physiology
Embryo, Nonmammalian/*physiology
Veins/*physiology
Zebrafish/*physiology
Zebrafish Proteins/*metabolism
Animals ; Animals, Genetically Modified/embryology ; Bone Morphogenetic Protein 2/genetics ; Bone Morphogenetic Protein 2/metabolism ; Embryo, Nonmammalian/cytology ; Veins/embryology ; Zebrafish/embryology ; Zebrafish Proteins/genetics
Czasopismo naukowe
Tytuł :
The distinctive role of tau and amyloid beta in mitochondrial dysfunction through alteration in Mfn2 and Drp1 mRNA Levels: A comparative study in Drosophila melanogaster.
Autorzy :
Abtahi SL; Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran.
Masoudi R; Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran. Electronic address: .
Haddadi M; Department of Biology, Faculty of Basic Sciences, University of Zabol, Zabol, Iran.
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Źródło :
Gene [Gene] 2020 Sep 05; Vol. 754, pp. 144854. Date of Electronic Publication: 2020 Jun 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Amyloid beta-Peptides/*metabolism
Animals, Genetically Modified/*metabolism
Drosophila melanogaster/*metabolism
Dynamins/*metabolism
GTP Phosphohydrolases/*metabolism
Mitochondrial Membrane Transport Proteins/*metabolism
RNA, Messenger/*metabolism
tau Proteins/*metabolism
Animals ; Animals, Genetically Modified/genetics ; Brain/metabolism ; Drosophila melanogaster/genetics ; Dynamins/genetics ; GTP Phosphohydrolases/genetics ; Gene Expression Regulation ; Memory Disorders/metabolism ; Memory Disorders/pathology ; Mitochondria/metabolism ; Mitochondrial Membrane Transport Proteins/genetics ; Phosphorylation ; RNA, Messenger/genetics ; tau Proteins/genetics
Czasopismo naukowe
Tytuł :
Diet type influences the gut microbiome and nutrient assimilation of Genetically Improved Farmed Tilapia (Oreochromis niloticus).
Autorzy :
Parata L; Centre for Marine Science and Innovation, School of Biological Earth and Environmental Science, University of New South Wales, Sydney, NSW, Australia.
Mazumder D; Centre for Marine Science and Innovation, School of Biological Earth and Environmental Science, University of New South Wales, Sydney, NSW, Australia.; Australian Nuclear Science and Technology Organisation, Kirrawee DC, NSW, Australia.
Sammut J; Centre for Marine Science and Innovation, School of Biological Earth and Environmental Science, University of New South Wales, Sydney, NSW, Australia.; Australian Nuclear Science and Technology Organisation, Kirrawee DC, NSW, Australia.
Egan S; Centre for Marine Science and Innovation, School of Biological Earth and Environmental Science, University of New South Wales, Sydney, NSW, Australia.
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Źródło :
PloS one [PLoS One] 2020 Aug 19; Vol. 15 (8), pp. e0237775. Date of Electronic Publication: 2020 Aug 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animal Feed*
Animals, Genetically Modified/*metabolism
Aquaculture/*methods
Cichlids/*metabolism
Gastrointestinal Microbiome/*physiology
Animals ; Animals, Genetically Modified/genetics ; Animals, Genetically Modified/microbiology ; Aquaculture/economics ; Aquaculture/organization & administration ; Cannibalism ; Cichlids/genetics ; Cichlids/microbiology ; DNA, Bacterial/isolation & purification ; Dietary Supplements/economics ; Efficiency, Organizational/economics ; Farms/economics ; Farms/organization & administration ; New South Wales ; Nutrients/metabolism ; RNA, Ribosomal, 16S/genetics
Czasopismo naukowe
Tytuł :
Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis.
Autorzy :
Ranadheera C; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.; Bioforensics Assay Development and Diagnostics, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Valcourt EJ; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.
Warner BM; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada.
Poliquin G; Office of the Scientific Director, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Rosenke K; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.
Frost K; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.
Tierney K; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.
Saturday G; Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.
Miao J; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.; Department of Pathology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, 450066, People's Republic of China.
Westover JB; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
Gowen BB; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
Booth S; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada.
Feldmann H; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA.
Wang Z; Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
Safronetz D; Zoonotic Diseases and Special Pathogens, National Microbiology Laboratories, Public Health Agency of Canada, Winnipeg, MB, Canada. .; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada. .
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 23; Vol. 10 (1), pp. 12378. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*/genetics
Animals, Genetically Modified*/metabolism
Animals, Genetically Modified*/virology
Disease Models, Animal*
Hemorrhagic Fever, Crimean*/genetics
Hemorrhagic Fever, Crimean*/metabolism
Hemorrhagic Fever, Crimean*/pathology
Hemorrhagic Fever Virus, Crimean-Congo/*metabolism
STAT2 Transcription Factor/*deficiency
Animals ; Cell Line ; Cricetinae ; Female ; Gene Knockout Techniques ; Hemorrhagic Fever Virus, Crimean-Congo/genetics ; Male ; STAT2 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł :
Generation of Marker-Free pbd-2 Knock-in Pigs Using the CRISPR/Cas9 and Cre/loxP Systems.
Autorzy :
Huang J; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
Wang A; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of China, Wuhan 430070, China.
Huang C; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.
Sun Y; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of China, Wuhan 430070, China.
Song B; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of China, Wuhan 430070, China.
Zhou R; State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.; International Research Center for Animal Disease, Ministry of Science and Technology of China, Wuhan 430070, China.
Li L; Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, China.; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture and Rural Affairs of China, Wuhan 430070, China.
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Źródło :
Genes [Genes (Basel)] 2020 Aug 18; Vol. 11 (8). Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*
CRISPR-Cas Systems*
Gene Knock-In Techniques*
Gene Targeting*
Homologous Recombination*
Integrases/*metabolism
beta-Defensins/*genetics
Animals ; Cells, Cultured ; Disease Resistance/genetics ; Fibroblasts/metabolism ; Gene Editing ; Gene Expression ; Gene Order ; Phenotype ; Plasmids/genetics ; Swine
Czasopismo naukowe
Tytuł :
The growth of endothelial-like cells in zebrafish embryoid body culture.
Autorzy :
Ibrahim M; Institute of Biology Leiden, Leiden University, The Netherlands; Animal Biotechnology Division, Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Pakistan.
Xie B; Institute of Biology Leiden, Leiden University, The Netherlands.
Richardson MK; Institute of Biology Leiden, Leiden University, The Netherlands. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2020 Jul 15; Vol. 392 (2), pp. 112032. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Animals, Genetically Modified/*embryology
Embryo, Nonmammalian/*cytology
Embryoid Bodies/*cytology
Embryonic Stem Cells/*cytology
Endothelial Cells/*cytology
Zebrafish/*embryology
Animals ; Animals, Genetically Modified/physiology ; Blastocyst/cytology ; Blastocyst/drug effects ; Blastocyst/metabolism ; Cells, Cultured ; Culture Media/pharmacology ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Embryoid Bodies/drug effects ; Embryoid Bodies/metabolism ; Embryonic Stem Cells/drug effects ; Embryonic Stem Cells/metabolism ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Green Fluorescent Proteins/metabolism ; Intercellular Signaling Peptides and Proteins/pharmacology ; Transcriptome ; Zebrafish/physiology
Czasopismo naukowe
Tytuł :
Multiple dengue virus serotypes resistant transgenic Aedes aegypti fitness evaluated under laboratory conditions.
Autorzy :
Ramyasoma HPBKD; Department of Chemistry, Faculty of Science, University of Colombo , Colombo, Sri Lanka.; Molecular Medicine Unit, Faculty of Medicine, University of Kelaniya , Kelaniya, Sri Lanka.
Dassanayake RS; Department of Chemistry, Faculty of Science, University of Colombo , Colombo, Sri Lanka.
Hapugoda M; Molecular Medicine Unit, Faculty of Medicine, University of Kelaniya , Kelaniya, Sri Lanka.
Capurro ML; Department of Parasitology (ICB), University of São Paulo , São Paulo, Brazil.
Silva Gunawardene YIN; Molecular Medicine Unit, Faculty of Medicine, University of Kelaniya , Kelaniya, Sri Lanka.
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Źródło :
RNA biology [RNA Biol] 2020 Jul; Vol. 17 (7), pp. 918-929. Date of Electronic Publication: 2020 Mar 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*
Genetic Fitness*
Serogroup*
Aedes/*genetics
Aedes/*virology
Dengue Virus/*classification
Mosquito Vectors/*genetics
Mosquito Vectors/*virology
Animals ; Dengue/transmission ; Dengue/virology ; Female ; Gene Expression ; Genetic Engineering ; Genetic Vectors/genetics ; Male ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Current progress of genome editing in livestock.
Autorzy :
Lee K; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, USA. Electronic address: .
Uh K; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, USA.
Farrell K; Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA, USA.
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Źródło :
Theriogenology [Theriogenology] 2020 Jul 01; Vol. 150, pp. 229-235. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Animals, Genetically Modified*
Gene Editing/*veterinary
Genetic Engineering/*veterinary
Livestock/*genetics
Animals ; CRISPR-Cas Systems
Czasopismo naukowe

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