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Wyszukujesz frazę ""Anthelmintics pharmacology"" wg kryterium: Temat


Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Simoben, Conrad
Robaa, Dina
Chakrabarti, Alokta
Schmidtkunz, Karin
Marek, Martin
Lancelot, Julien
Kannan, Srinivasaraghavan
Melesina, Jelena
Shaik, Tajith
Pierce, Raymond
Romier, Christophe
Jung, Manfred
Sippl, Wolfgang
Pokaż więcej
Temat :
crystal structure
docking
epigenetics
histone deacetylase (HDAC) inhibitors
schistosomiasis
virtual screening
MESH: Animals
MESH: Anthelmintics/pharmacology
MESH: Hydroxamic Acids/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Apoptosis/drug effects
MESH: Molecular Docking Simulation
MESH: Protein Binding
MESH: Protein Interaction Domains and Motifs
MESH: Protein Structure, Secondary
MESH: Pyrrolidines/chemical synthesis
MESH: Pyrrolidines/pharmacology
MESH: Schistosoma mansoni/drug effects
MESH: Helminth Proteins/chemistry
MESH: Schistosoma mansoni/enzymology
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
MESH: Binding Sites
MESH: Structure-Activity Relationship
MESH: Zinc/chemistry
MESH: Zinc/metabolism
MESH: Chelating Agents/chemical synthesis
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
MESH: Helminth Proteins/genetics
MESH: Crystallography, X-Ray
MESH: Gene Expression
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Helminth Proteins/metabolism
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Histone Deacetylase Inhibitors/pharmacology
MESH: Histone Deacetylases/chemistry
MESH: Histone Deacetylases/genetics
MESH: Histone Deacetylases/metabolism
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Źródło :
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Conrad V. Simoben
Dina Robaa
Alokta Chakrabarti
Karin Schmidtkunz
Martin Marek
Julien Lancelot
Srinivasaraghavan Kannan
Jelena Melesina
Tajith B. Shaik
Raymond J. Pierce
Christophe Romier
Manfred Jung
Wolfgang Sippl
Pokaż więcej
Temat :
MESH: Molecular Docking Simulation
MESH: Animals
virtual screening
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
QD241-441
MESH: Schistosoma mansoni/drug effects
MESH: Crystallography, X-Ray
MESH: Histone Deacetylases/genetics
MESH: Pyrrolidines/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Schistosoma mansoni/enzymology
epigenetics
MESH: Helminth Proteins/metabolism
MESH: Binding Sites
MESH: Histone Deacetylase Inhibitors/pharmacology
Organic chemistry
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Zinc/chemistry
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Zinc/metabolism
schistosomiasis
MESH: Hydroxamic Acids/chemical synthesis
histone deacetylase (HDAC) inhibitors
MESH: Protein Interaction Domains and Motifs
MESH: Histone Deacetylases/metabolism
MESH: Protein Structure, Secondary
MESH: Apoptosis/drug effects
MESH: Chelating Agents/chemical synthesis
MESH: Gene Expression
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Article
MESH: Anthelmintics/pharmacology
MESH: Helminth Proteins/genetics
docking
MESH: Protein Binding
MESH: Helminth Proteins/chemistry
MESH: Pyrrolidines/pharmacology
crystal structure
MESH: Histone Deacetylases/chemistry
MESH: Structure-Activity Relationship
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
Źródło :
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 3, p 566 (2018)
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
P-glycoproteins play a role in ivermectin resistance in cyathostomins☆
Autorzy :
L.E. Peachey
G.L. Pinchbeck
J.B. Matthews
F.A. Burden
A. Lespine
G. von Samson-Himmelstjerna
J. Krücken
J.E. Hodgkinson
Pokaż więcej
Temat :
Anthelmintic resistance
Cyathostomins
Ivermectin
P-glycoproteins
Horses/parasitology
Levamisole/pharmacology
ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors
Drug Resistance/genetics
Anthelmintics/pharmacology
Strongyloidea/drug effects
Ivermectin/pharmacology
Larva/drug effects
Lactones/pharmacology
Article
RC109-216
embryonic structures
Infectious and parasitic diseases
urogenital system
Journal Article
Animals
Źródło :
International Journal for Parasitology: Drugs and Drug Resistance 3 (7), 388-398. (2017)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 7, Iss 3, Pp 388-398 (2017)
Peachey, L E, Pinchbeck, G L, Matthews, J B, Burden, F A, Lespine, A, von Samson-Himmelstjerna, G, Krücken, J & Hodgkinson, J E 2017, ' P-glycoproteins play a role in ivermectin resistance in cyathostomins ', International Journal for Parasitology: Drugs and Drug Resistance, vol. 7, no. 3, pp. 388-398 . https://doi.org/10.1016/j.ijpddr.2017.10.006
Opis pliku :
application/pdf

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