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Wyszukujesz frazę ""Anti-HIV Agents"" wg kryterium: Temat


Tytuł:
Identification of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase.
Autorzy:
Feng D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China. Electronic address: .
Zuo X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Zhao F; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Lin H; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Dai J; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Sun Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Clercq E; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000, Leuven, Belgium.
Pannecouque C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000, Leuven, Belgium.
Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012, Jinan, Shandong, PR China. Electronic address: .
Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2023 Feb 05; Vol. 247, pp. 115045. Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/chemistry
HIV-1*
Structure-Activity Relationship ; Drug Design ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/chemistry ; HIV Reverse Transcriptase ; Molecular Structure
Czasopismo naukowe
Tytuł:
Interrogating the promise of long-acting HIV pre-exposure prophylaxis.
Autorzy:
Pike C; Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Electronic address: Carey.Pike@hiv-research.org.za.
Bekker LG; Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
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Źródło:
Trends in molecular medicine [Trends Mol Med] 2023 Feb; Vol. 29 (2), pp. 93-98. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*/prevention & control
HIV Infections*/drug therapy
Pre-Exposure Prophylaxis*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Incidence ; Health Status
Czasopismo naukowe
Tytuł:
Anti-HIV Potential of Beesioside I Derivatives as Maturation Inhibitors: Synthesis, 3D-QSAR, Molecular Docking and Molecular Dynamics Simulations.
Autorzy:
Zhao Z; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Ma Y; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Li X; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Morris-Natschke SL; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.
Sun Z; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Sun Z; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Ma G; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Dong Z; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Zhao X; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Yang M; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Xu X; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Lee K; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.
Wu H; Beijing Key Laboratory of New Drug Discovery Based on Classic Chinese Medicine Prescription, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.
Chen C; Antiviral Drug Discovery Laboratory, Surgical Oncology Research Facility, Duke University Medical Center, Durham, NC 27710, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 11; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Virus Replication*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/chemistry
Molecular Docking Simulation ; Molecular Dynamics Simulation ; Quantitative Structure-Activity Relationship ; Capsid Proteins/chemistry
Czasopismo naukowe
Tytuł:
Covalently Targeted Highly Conserved Tyr318 to Improve the Drug Resistance Profiles of HIV-1 NNRTIs: A Proof-of-Concept Study.
Autorzy:
Zhou Z; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Meng B; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
An J; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Zhao F; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Sun Y; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Zeng D; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Wang W; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Gao S; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Xia Y; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
Dun C; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.
De Clercq E; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
Pannecouque C; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium.
Zhan P; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Shandong University, 44 West Culture Road, Jinan 250012, China.
Kang D; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Shandong University, 44 West Culture Road, Jinan 250012, China.
Liu X; Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, Jinan 250012, China.; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, Shandong University, 44 West Culture Road, Jinan 250012, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 07; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/metabolism
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/chemistry
Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/chemistry ; HIV Reverse Transcriptase/metabolism ; Drug Design ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Analysis of mutational history of multidrug-resistant genotypes with a mutagenetic tree model.
Autorzy:
Pirkl M; Institute of Virology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Büch J; Institute of Virology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Devaux C; Department of Infection and Immunity, Luxembourg Institute of Health, Strassen, Luxembourg.
Böhm M; Institute of Virology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Sönnerborg A; Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institute, Solna, Sweden.
Incardona F; EuResist Network, Roma, Italy.; InformaPRO, Roma, Italy.
Abecasis A; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
Vandamme AM; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.; Department of Microbiology, Immunology and Transplantation, Clinical and Epidemiological Virology, Institute for the Future, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Zazzi M; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Kaiser R; Institute of Virology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Lengauer T; Institute of Virology, University Hospital Cologne, University of Cologne, Cologne, Germany.
The EuResist Network Study Group
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Źródło:
Journal of medical virology [J Med Virol] 2023 Jan; Vol. 95 (1), pp. e28389.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/drug therapy
HIV-1*/genetics
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Mutation ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Genotype ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Tytuł:
Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal.
Autorzy:
Kuehnemann C; Buck Institute for Research on Aging, Novato, California, USA.; University of Southern California, Los Angeles, California, USA.; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Hughes JB; Buck Institute for Research on Aging, Novato, California, USA.
Desprez PY; Buck Institute for Research on Aging, Novato, California, USA.; California Pacific Medical Center, San Francisco, California, USA.
Melov S; Buck Institute for Research on Aging, Novato, California, USA.
Wiley CD; Buck Institute for Research on Aging, Novato, California, USA.; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Campisi J; Buck Institute for Research on Aging, Novato, California, USA.
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Źródło:
Aging cell [Aging Cell] 2023 Jan; Vol. 22 (1), pp. e13750. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Protease Inhibitors*/pharmacology
HIV Protease Inhibitors*/therapeutic use
HIV Infections*/drug therapy
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Aging, Premature*
Animals ; Mice ; Ritonavir/pharmacology ; Ritonavir/therapeutic use ; Atazanavir Sulfate/pharmacology ; Atazanavir Sulfate/therapeutic use ; Darunavir/pharmacology ; Darunavir/therapeutic use ; Cellular Senescence
Czasopismo naukowe
Tytuł:
Prevalence of drug resistant HIV-1 forms in patients without any history of antiretroviral therapy in the Republic of Guinea.
Autorzy:
Shchemelev AN; Saint Petersburg Pasteur Institute, St. Petersburg, Russia.
Boumbaly S; Institute Research Biology Appliquee De Guinee, Kindia, Republic of Guinea.
Ostankova YV; Saint Petersburg Pasteur Institute, St. Petersburg, Russia.
Zueva EB; Saint Petersburg Pasteur Institute, St. Petersburg, Russia.
Semenov AV; ERIVI, FBRI SRC VB 'Vector', Rospotrebnadzor, Ekaterinburg, Russia.
Totolian AA; Saint Petersburg Pasteur Institute, St. Petersburg, Russia.
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Źródło:
Journal of medical virology [J Med Virol] 2023 Jan; Vol. 95 (1), pp. e28184. Date of Electronic Publication: 2022 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Prevalence ; Guinea/epidemiology ; Drug Resistance, Viral/genetics ; Mutation ; Genotype ; Phylogeny
Czasopismo naukowe
Tytuł:
Efavirenz: History, Development and Future.
Autorzy:
Costa B; OncoPharma Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.; , Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal.; Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.
Vale N; OncoPharma Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.; , Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal.; Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.
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Źródło:
Biomolecules [Biomolecules] 2022 Dec 31; Vol. 13 (1). Date of Electronic Publication: 2022 Dec 31.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Humans ; Reverse Transcriptase Inhibitors/therapeutic use ; Reverse Transcriptase Inhibitors/adverse effects ; Benzoxazines/adverse effects
Czasopismo naukowe
Tytuł:
Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
Autorzy:
Lu H; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
Komukai Y; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
Usami K; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
Guo Y; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
Qiao X; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
Nukaga M; Faculty of Pharmaceutical Sciences, Josai International University Gumyo 1, Togane-shi Chiba 283-8555, Japan.
Hoshino T; Graduate School of Pharmaceutical Sciences, Chiba University Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2022 Dec 26; Vol. 62 (24), pp. 6762-6774. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/drug effects
HIV-1*/enzymology
Ribonuclease H*/antagonists & inhibitors
Anti-HIV Agents*/chemistry
Anti-HIV Agents*/pharmacology
Humans ; Catalytic Domain ; Crystallography, X-Ray ; Furans/pharmacology ; Furans/chemistry ; HIV Reverse Transcriptase ; Metals/metabolism ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/chemistry
Czasopismo naukowe
Tytuł:
Daphnepedunins A-F, Anti-HIV Macrocyclic Daphnane Orthoester Diterpenoids from Daphne pedunculata .
Autorzy:
Tan L; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Otsuki K; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Zhang M; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Kikuchi T; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Okayasu M; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Azumaya I; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Zhou D; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Li N; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Huang L; Surgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States.
Chen CH; Surgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States.
Li W; Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
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Źródło:
Journal of natural products [J Nat Prod] 2022 Dec 23; Vol. 85 (12), pp. 2856-2864. Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Daphne*/chemistry
Thoracica*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/chemistry
Diterpenes*/pharmacology
Diterpenes*/chemistry
Animals ; Molecular Structure
Czasopismo naukowe
Tytuł:
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability.
Autorzy:
Xie X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zheng YG; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences /Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.; School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, China.; Department of Pharmacy, Guangdong Women and Children Hospital, Guangzhou 511400, China.
Chen H; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences /Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Li J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Luo RH; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences /Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Chen L; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Zheng CB; School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, China.
Zhang S; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Lingang Laboratory, Shanghai 200031, China.
Peng P; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Ma D; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Yang LM; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences /Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Zheng YT; Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences /Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Liu H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Wang J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Lingang Laboratory, Shanghai 200031, China.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2022 Dec 22; Vol. 65 (24), pp. 16526-16540. Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
HIV-1*
Rats ; Animals ; Maraviroc/pharmacology ; CCR5 Receptor Antagonists/pharmacology ; Cyclohexanes/pharmacology ; Triazoles/pharmacology ; Triazoles/therapeutic use ; Biological Availability ; Rats, Sprague-Dawley ; Tropanes/pharmacology ; Receptors, CCR5/metabolism
Czasopismo naukowe
Tytuł:
Added Value of Next Generation over Sanger Sequencing in Kenyan Youth with Extensive HIV-1 Drug Resistance.
Autorzy:
Novitsky V; Brown University, Providence, Rhode Island, USA.
Nyandiko W; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.; Moi University, Eldoret, Kenya.
Vreeman R; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.; Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Arnhold Institute for Global Health, New York, New York, USA.
DeLong AK; Brown University, Providence, Rhode Island, USA.
Manne A; Brown University, Providence, Rhode Island, USA.
Scanlon M; Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Arnhold Institute for Global Health, New York, New York, USA.
Ngeresa A; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Aluoch J; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Sang F; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Ashimosi C; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Jepkemboi E; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Orido M; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Hogan JW; Brown University, Providence, Rhode Island, USA.
Kantor R; Brown University, Providence, Rhode Island, USA.
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Corporate Authors:
RESistance in a PEdiatric CohorT (RESPECT) Study
Źródło:
Microbiology spectrum [Microbiol Spectr] 2022 Dec 21; Vol. 10 (6), pp. e0345422. Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV-1*/genetics
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Child ; Humans ; Adolescent ; Kenya ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Drug Resistance, Viral/genetics ; Genotype ; Viral Load ; Mutation ; High-Throughput Nucleotide Sequencing
Czasopismo naukowe
Tytuł:
High Drug Resistance Levels Compromise the Control of HIV Infection in Pediatric and Adult Populations in Bata, Equatorial Guinea.
Autorzy:
Rodríguez-Galet A; HIV-1 Molecular Epidemiology Laboratory, Microbiology and Parasitology Department, Hospital Ramón y Cajal-IRYCIS and CIBEREsp-RITIP-CoRISpe, 20834 Madrid, Spain.
Ventosa-Cubillo J; HIV-1 Molecular Epidemiology Laboratory, Microbiology and Parasitology Department, Hospital Ramón y Cajal-IRYCIS and CIBEREsp-RITIP-CoRISpe, 20834 Madrid, Spain.; Fundación Estatal, Salud, Infancia y Bienestar Social (CSAI), 28029 Madrid, Spain.
Bendomo V; Unidad de Referencia de Enfermedades Infecciosas (UREI), Hospital Regional de Bata, Bata 88240, Equatorial Guinea.
Eyene M; Unidad de Referencia de Enfermedades Infecciosas (UREI), Hospital Regional de Bata, Bata 88240, Equatorial Guinea.
Mikue-Owono T; Laboratorio de Análisis Clínicos, Hospital Regional de Bata, Bata 88240, Equatorial Guinea.
Nzang J; Fundación Estatal, Salud, Infancia y Bienestar Social (CSAI), 28029 Madrid, Spain.
Ncogo P; Fundación Estatal, Salud, Infancia y Bienestar Social (CSAI), 28029 Madrid, Spain.
Gonzalez-Alba JM; Grupo de Investigación en Microbiología Translacional, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Microbiology Department, Hospital Universitario Central de Asturias (HUCA), 33011 Oviedo, Spain.
Benito A; Centro Nacional de Medicina Tropical (CNMT), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), 28029 Madrid, Spain.
Holguín Á; HIV-1 Molecular Epidemiology Laboratory, Microbiology and Parasitology Department, Hospital Ramón y Cajal-IRYCIS and CIBEREsp-RITIP-CoRISpe, 20834 Madrid, Spain.; Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
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Źródło:
Viruses [Viruses] 2022 Dec 21; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV-1*/genetics
HIV Seropositivity*
Adolescent ; Humans ; Child ; Adult ; Equatorial Guinea/epidemiology ; Delayed Diagnosis ; Drug Resistance, Viral/genetics ; Viral Load ; Mutation
Czasopismo naukowe
Tytuł:
Medicinal Chemistry of Anti-HIV-1 Latency Chemotherapeutics: Biotargets, Binding Modes and Structure-Activity Relationship Investigation.
Autorzy:
Wang YK; School of Pharmacy and Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, NHC Key Laboratory of Biotechnology Drugs (Shandong Academy of Medical Sciences), Key Laboratory for Rare & Uncommon Disease of Shandong Province, No 6699, Qingdao Road, Ji'nan 250117, China; Key Laboratory of Forensic Toxicology, Ministry of Public Security, Beijing 100192, China.
Wei L; School of Pharmacy and Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, NHC Key Laboratory of Biotechnology Drugs (Shandong Academy of Medical Sciences), Key Laboratory for Rare & Uncommon Disease of Shandong Province, No 6699, Qingdao Road, Ji'nan 250117, China; Key Laboratory of Forensic Toxicology, Ministry of Public Security, Beijing 100192, China.
Hu W; Shandong University, No 72, Binhai Road, Qingdao 266237, China.
Yu PX; Shandong University, No 72, Binhai Road, Qingdao 266237, China.
Li Z; Shandong University, No 72, Binhai Road, Qingdao 266237, China.
Yu HP; Shandong University, No 72, Binhai Road, Qingdao 266237, China.
Li X; School of Pharmacy and Pharmaceutical Sciences & Institute of Materia Medica, Shandong First Medical University & Shandong Academy of Medical Sciences, NHC Key Laboratory of Biotechnology Drugs (Shandong Academy of Medical Sciences), Key Laboratory for Rare & Uncommon Disease of Shandong Province, No 6699, Qingdao Road, Ji'nan 250117, China; Key Laboratory of Forensic Toxicology, Ministry of Public Security, Beijing 100192, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 20; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
HIV Infections*
HIV-1*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Virus Activation ; Virus Latency ; Chemistry, Pharmaceutical ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Nevirapine plasma concentration is associated with virologic failure and the emergence of drug-resistant mutations among HIV patients in Kenya: A cross sectional study.
Autorzy:
Omondi EO; Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Muigai A; Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Ngayo MO; Department of Botany, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Mungiria J; Department of Botany, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Lihana R; Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya.
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Źródło:
Medicine [Medicine (Baltimore)] 2022 Dec 16; Vol. 101 (50), pp. e32346.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/drug therapy
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV-1*/genetics
Humans ; Adult ; Nevirapine/pharmacology ; Nevirapine/therapeutic use ; Cross-Sectional Studies ; Reverse Transcriptase Inhibitors/therapeutic use ; Kenya ; Mutation ; Drug Resistance, Viral/genetics ; Viral Load
Czasopismo naukowe
Tytuł:
Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Autorzy:
Curreli F; Laboratory of Molecular Modeling and Drug Design, Lindsey F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
Kwon YD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Nicolau I; Laboratory of Molecular Modeling and Drug Design, Lindsey F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
Burgos G; Laboratory of Molecular Modeling and Drug Design, Lindsey F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
Altieri A; EDASA Scientific srls, Via Stingi 37, 66050 San Salvo, Italy.
Kurkin AV; EDASA Scientific srls, Via Stingi 37, 66050 San Salvo, Italy.
Verardi R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Debnath AK; Laboratory of Molecular Modeling and Drug Design, Lindsey F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 15; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*/metabolism
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/chemistry
Thiazoles/pharmacology ; HIV Envelope Protein gp120/metabolism ; CD4 Antigens/metabolism
Czasopismo naukowe
Tytuł:
In Vitro Susceptibility of HIV Isolates with High Growth Capability to Antiretroviral Drugs.
Autorzy:
Hinay AA Jr; Division of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Kanai K; Division of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Tsuneki-Tokunaga A; Division of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Komatsu M; Division of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
Telan EO; National Reference Laboratory, STD AIDS Cooperative Central Laboratory, San Lazaro Hospital, Manila 1003, Metro Manila, Philippines.
Kageyama S; Division of Virology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 06; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:
Journal Article
MeSH Terms:
HIV-1*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Humans ; Leukocytes, Mononuclear ; Reverse Transcriptase Inhibitors/pharmacology ; Mutation ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Tytuł:
The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy.
Autorzy:
Bianco MDCAD; Programa de Pos-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas-ICB, Universidade Federal do Rio de Janeiro-UFRJ, Av. Carlos Chagas Filho, 373, Bloco L, Rio de Janeiro 21941-902, Brazil.; Laboratorio de Sintese de Farmacos-LASFAR-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Farmanguinhos-Fiocruz, Rua Sizenando Nabuco, 100-Manguinhos, Rio de Janeiro 21041-000, Brazil.; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy.
Inacio Leite D; Laboratorio de Sintese de Farmacos-LASFAR-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Farmanguinhos-Fiocruz, Rua Sizenando Nabuco, 100-Manguinhos, Rio de Janeiro 21041-000, Brazil.
Silva Castelo Branco F; Laboratorio de Sintese de Farmacos-LASFAR-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Farmanguinhos-Fiocruz, Rua Sizenando Nabuco, 100-Manguinhos, Rio de Janeiro 21041-000, Brazil.
Boechat N; Programa de Pos-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas-ICB, Universidade Federal do Rio de Janeiro-UFRJ, Av. Carlos Chagas Filho, 373, Bloco L, Rio de Janeiro 21941-902, Brazil.; Laboratorio de Sintese de Farmacos-LASFAR-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Farmanguinhos-Fiocruz, Rua Sizenando Nabuco, 100-Manguinhos, Rio de Janeiro 21041-000, Brazil.
Uliassi E; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy.
Bolognesi ML; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy.
Bastos MM; Programa de Pos-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas-ICB, Universidade Federal do Rio de Janeiro-UFRJ, Av. Carlos Chagas Filho, 373, Bloco L, Rio de Janeiro 21941-902, Brazil.; Laboratorio de Sintese de Farmacos-LASFAR-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Farmanguinhos-Fiocruz, Rua Sizenando Nabuco, 100-Manguinhos, Rio de Janeiro 21041-000, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 03; Vol. 27 (23). Date of Electronic Publication: 2022 Dec 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acquired Immunodeficiency Syndrome*/drug therapy
HIV-1*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Humans ; Zidovudine/pharmacology ; Zidovudine/therapeutic use ; Pharmacophore ; Viral Load
Czasopismo naukowe
Tytuł:
Doravirine-associated resistance mutations in antiretroviral therapy naïve and experienced adults with HIV-1 subtype C infection in Botswana.
Autorzy:
Bareng OT; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Medical Sciences, Faculty of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Seselamarumo S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Biological Sciences, Faculty of Science, University of Botswana, Gaborone, Botswana.
Seatla KK; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Medical Sciences, Faculty of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Choga WT; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Bakae B; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Maruapula D; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Biological Sciences, Faculty of Science, University of Botswana, Gaborone, Botswana.
Kelentse N; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Medical Sciences, Faculty of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Moraka NO; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Division of Medical Virology, Stellenbosch University, Cape Town, South Africa.
Mokaleng B; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Medical Sciences, Faculty of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Mokgethi PT; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Biological Sciences, Faculty of Science, University of Botswana, Gaborone, Botswana.
Ditlhako TR; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Pretorius-Holme M; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Mbulawa MB; Ministry of Health, Republic of Botswana, Gaborone, Botswana.
Lebelonyane R; Ministry of Health, Republic of Botswana, Gaborone, Botswana.
Bile EC; FHI 360, Department of Clinical Sciences, Durham, North Carolina, USA.
Gaolathe T; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Shapiro R; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Makhema JM; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Lockman S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Brigham and Women's Hospital, Boston, Massachusetts, USA.
Essex M; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Novitsky V; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Mpoloka SW; Department of Biological Sciences, Faculty of Science, University of Botswana, Gaborone, Botswana.
Moyo S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Gaseitsiwe S; Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. Electronic address: .
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Źródło:
Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2022 Dec; Vol. 31, pp. 128-134. Date of Electronic Publication: 2022 Aug 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
HIV-1*/genetics
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/epidemiology
Adult ; Humans ; Drug Resistance, Viral/genetics ; Cross-Sectional Studies ; Retrospective Studies ; Botswana ; Mutation
Czasopismo naukowe
Tytuł:
Virological efficacy of switch to DTG plus 3TC in a retrospective observational cohort of suppressed HIV-1 patients with or without past M184V: the LAMRES study.
Autorzy:
Santoro MM; Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy. Electronic address: .
Armenia D; Saint Camillus International University of Health Sciences, Rome, Italy.
Teyssou E; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Paris, France.
Santos JR; Fight AIDS and Infectious Diseases Foundation, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Charpentier C; Service de Virologie, Université de Paris, INSERM, IAME, Hôpital Bichat-Claude Bernard, Paris, France.
Lambert-Niclot S; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Universitaire Saint Antoine, laboratoire de virologie, Paris, France.
Antinori A; Infectious Disease-Clinical Department, National Institute for Infectious Diseases 'L. Spallanzani', IRCCS, Rome, Italy.
Katlama C; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Paris, France.
Descamps D; Service de Virologie, Université de Paris, INSERM, IAME, Hôpital Bichat-Claude Bernard, Paris, France.
Perno CF; Multimodal Laboratory Research Department, Children Hospital Bambino Gesù, IRCCS, Rome, Italy.
Calvez V; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Paris, France.
Paredes R; Fight AIDS and Infectious Diseases Foundation, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Ceccherini-Silberstein F; Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Marcelin AG; Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Paris, France.
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Corporate Authors:
LAMRES Study Group
Źródło:
Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2022 Dec; Vol. 31, pp. 52-62. Date of Electronic Publication: 2022 Aug 07.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/genetics
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
HIV Infections*/drug therapy
Humans ; Retrospective Studies ; Lamivudine/therapeutic use ; Lamivudine/pharmacology
Czasopismo naukowe

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