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Wyszukujesz frazę ""Anti-Inflammatory Agents"" wg kryterium: Temat


Tytuł:
Design, Synthesis and Evaluation of Antioxidant and NSAID Derivatives with Antioxidant, Anti-Inflammatory and Plasma Lipid Lowering Effects.
Autorzy:
Theodosis-Nobelos P; Department of Pharmacy, School of Health Sciences, Frederick University, Nicosia 1036, Cyprus.
Marc G; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 41 Victor Babeș Street, RO-400010 Cluj-Napoca, Romania.
Rekka EA; Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, 54124 Thessaloniki, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 26; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/chemistry
Antioxidants*/chemistry
Rats ; Animals ; Lipid Peroxidation ; Anti-Inflammatory Agents/pharmacology ; Triglycerides ; Edema/drug therapy ; Carrageenan/adverse effects
Czasopismo naukowe
Tytuł:
Design, synthesis, biological evaluation, and in silico studies of quinoxaline derivatives as potent p38α MAPK inhibitors.
Autorzy:
Anjali; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Kamboj P; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Alam O; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Patel H; Department of Pharmaceutical Chemistry, Division of Computer Aided Drug Design, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India.
Ahmad I; Department of Pharmaceutical Chemistry, Prof. Ravindra Nikam College of Pharmacy, Gondur, Dhule, Maharashtra, India.
Ahmad SS; Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
Amir M; Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Jan; Vol. 357 (1), pp. e2300301. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Mitogen-Activated Protein Kinase 14*
Rats ; Animals ; Diclofenac/pharmacology ; Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Quinoxalines/pharmacology ; Anti-Inflammatory Agents/pharmacology ; Protein Kinase Inhibitors/chemistry ; Drug Design
Czasopismo naukowe
Tytuł:
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents.
Autorzy:
Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Brogi S; Department of Pharmacy, University of Pisa, Pisa, Italy.
S Tawfik S; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Othman DIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Elshal M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Ur Rahman H; Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Parambi DGT; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
M Elbargisy R; Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Selim S; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Mostafa EM; Department of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Mohamed AAB; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2162511.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Antipyrine*/pharmacology
Humans ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Celecoxib/pharmacology ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Drug Design ; Edema/drug therapy ; Molecular Docking Simulation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Repurposing anti-inflammatory drugs for fighting planktonic and biofilm growth. New carbazole derivatives based on the NSAID carprofen: synthesis, in silico and in vitro bioevaluation.
Autorzy:
Dumitrascu F; 'C. D. Nenitzescu' Institute of Organic and Supramolecular Chemistry, Center for Organic Chemistry, Bucharest, Romania.
Caira MR; Department of Chemistry, University of Cape Town, Cape Town, South Africa.
Avram S; Department of Anatomy, Animal Physiology, and Biophysics, Faculty of Biology, University of Bucharest, Bucharest, Romania.
Buiu C; Department of Automatic Control and Systems Engineering, Politehnica University of Bucharest, Bucharest, Romania.
Udrea AM; Laser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, Romania.; Research Institute of the University of Bucharest-ICUB, University of Bucharest, Bucharest, Romania.
Vlad IM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
Zarafu I; Department of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Bucharest, Romania.
Ioniță P; Department of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, Bucharest, Romania.
Nuță DC; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
Popa M; Research Institute of the University of Bucharest-ICUB, University of Bucharest, Bucharest, Romania.
Chifiriuc MC; Research Institute of the University of Bucharest-ICUB, University of Bucharest, Bucharest, Romania.; Department of Botany and Microbiology, University of Bucharest, Bucharest, Romania.; Biological Sciences Section, Romanian Academy, Bucharest, Romania.
Limban C; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Aug 23; Vol. 13, pp. 1181516. Date of Electronic Publication: 2023 Aug 23 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*
Chlorine*
Bromine ; Antioxidants/pharmacology ; Drug Repositioning ; Anti-Inflammatory Agents ; Carbazoles/pharmacology ; Anti-Bacterial Agents/pharmacology ; Biofilms
Czasopismo naukowe
Tytuł:
Synthesis and Biological Evaluation of Gentiopicroside Derivatives as Novel Cyclooxygenase-2 Inhibitors with Anti-Inflammatory Activity.
Autorzy:
Ren G; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.
Zhang Q; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou, 730000, People's Republic of China.
Xia P; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou, 730000, People's Republic of China.; Key Laboratory of Chemistry and Quality of TCM of the College of Gansu Province, Lanzhou, 730000, People's Republic of China.; Gansu Province Engineering Laboratory for TCM Standardization Technology and Popularization, Lanzhou, 730000, People's Republic of China.
Wang J; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.
Fang P; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.
Jin X; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.
Peng X; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou, 730000, People's Republic of China.; Key Laboratory of Chemistry and Quality of TCM of the College of Gansu Province, Lanzhou, 730000, People's Republic of China.; Gansu Province Engineering Laboratory for TCM Standardization Technology and Popularization, Lanzhou, 730000, People's Republic of China.
Xu Y; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Lanzhou Institute for Food and Drug Control, Lanzhou, 730000, People's Republic of China.
Zhang J; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou, 730000, People's Republic of China.; Key Laboratory of Chemistry and Quality of TCM of the College of Gansu Province, Lanzhou, 730000, People's Republic of China.; Gansu Province Engineering Laboratory for TCM Standardization Technology and Popularization, Lanzhou, 730000, People's Republic of China.
Zhao L; Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.; Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou, 730000, People's Republic of China.; Key Laboratory of Chemistry and Quality of TCM of the College of Gansu Province, Lanzhou, 730000, People's Republic of China.; Gansu Province Engineering Laboratory for TCM Standardization Technology and Popularization, Lanzhou, 730000, People's Republic of China.; Lanzhou Institute for Food and Drug Control, Lanzhou, 730000, People's Republic of China.
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Źródło:
Drug design, development and therapy [Drug Des Devel Ther] 2023 Mar 23; Vol. 17, pp. 919-935. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Cyclooxygenase 2 Inhibitors*/chemistry
Anti-Inflammatory Agents*/therapeutic use
Mice ; Animals ; Cyclooxygenase 2/metabolism ; Molecular Docking Simulation ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Structure-Activity Relationship ; Molecular Structure ; Edema/chemically induced ; Edema/drug therapy
Czasopismo naukowe
Tytuł:
Synthesis, In Vitro Anti-Inflammatory Activity, and HRMS Analysis of New Amphetamine Derivatives.
Autorzy:
Manolov S; Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria.
Ivanov I; Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria.
Bojilov D; Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria.
Nedialkov P; Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 24; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Anti-Inflammatory Agents, Non-Steroidal*/chemistry
Ketoprofen*/chemistry
Amphetamine/pharmacology ; Ibuprofen/chemistry ; Naproxen/chemistry ; Anti-Inflammatory Agents/pharmacology
Czasopismo naukowe
Tytuł:
Celastrol regulates psoriatic inflammation and autophagy by targeting IL-17A.
Autorzy:
Park A; Laboratory of PharmacoImmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si, Gyeonggi-do 14662, Republic of Korea.
Heo TH; Laboratory of PharmacoImmunology, Integrated Research Institute of Pharmaceutical Sciences and BK21 FOUR Team for Advanced Program for SmartPharma Leaders, College of Pharmacy, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si, Gyeonggi-do 14662, Republic of Korea. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Mar; Vol. 172, pp. 116256. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Interleukin-17*/antagonists & inhibitors
Pentacyclic Triterpenes*/therapeutic use
Psoriasis*/drug therapy
Animals ; Mice ; Autophagy ; Cytokines ; Inflammation/drug therapy
Czasopismo naukowe
Tytuł:
Design and synthesis of novel dithiazole carboxylic acid Derivatives: In vivo and in silico investigation of their Anti-Inflammatory and analgesic effects.
Autorzy:
Yücel NT; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
Asfour AAR; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
Evren AE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey; Pharmacy Services, Vocational School of Health Services, Bilecik Seyh Edebali University, Bilecik 11100, Turkey. Electronic address: .
Yazıcı C; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
Kandemir Ü; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey; Department of Medical Services and Techniques, Vocational School of Health Services, Bilecik Şeyh Edebali University, Bilecik 11100, Turkey.
Özkay ÜD; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
Can ÖD; Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
Yurttaş L; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26100, Turkey.
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2024 Mar; Vol. 144, pp. 107120. Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Analgesics*/pharmacology
Analgesics*/therapeutic use
Analgesics*/chemistry
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Anti-Inflammatory Agents*/chemistry
Animals ; Mice ; Rats ; Carboxylic Acids/pharmacology ; Carrageenan ; Edema/chemically induced ; Edema/drug therapy ; Edema/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Molecular Docking Simulation ; Organic Chemicals ; Isothiuronium/analogs & derivatives ; Isothiuronium/chemistry ; Isothiuronium/pharmacology
Czasopismo naukowe
Tytuł:
The formyl peptide receptors FPR1 and FPR2 as targets for inflammatory disorders: recent advances in the development of small-molecule agonists.
Autorzy:
Yi X; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia.
Tran E; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia.
Odiba JO; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia.
Qin CX; Drug Discovery Biology, Monash Institute of Pharmaceutical Science, Monash University, Parkville, Victoria, 3052, Australia; Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria, 3004, Australia. Electronic address: .
Ritchie RH; Drug Discovery Biology, Monash Institute of Pharmaceutical Science, Monash University, Parkville, Victoria, 3052, Australia; Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria, 3004, Australia. Electronic address: .
Baell JB; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, 3052, Australia. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 05; Vol. 265, pp. 115989. Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neutrophils*
Receptors, Formyl Peptide*/agonists
Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/pharmacology
Czasopismo naukowe
Tytuł:
The protective effect of Ergolide in osteoarthritis: In vitro and in vivo studies.
Autorzy:
Meng X; Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China; Department of Sports Medicine, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China; Institute of Sports Medicine and Osteoarthropathy of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Sun L; Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Meng X; The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Bi Q; Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China; Department of Sports Medicine, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China; Institute of Sports Medicine and Osteoarthropathy of Hangzhou Medical College, Hangzhou, Zhejiang, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Jan 25; Vol. 127, pp. 111355. Date of Electronic Publication: 2023 Dec 28.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Anti-Inflammatory Agents*/metabolism
Osteoarthritis*/metabolism
Lactones*
Sesquiterpenes*
Animals ; Inflammation/drug therapy ; NF-kappa B/metabolism ; Chondrocytes ; p38 Mitogen-Activated Protein Kinases/metabolism ; Interleukin-1beta/metabolism ; Cyclooxygenase 2/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł:
A decade of USFDA-approved small molecules as anti-inflammatory agents: Recent trends and Commentaries on the "industrial" perspective.
Autorzy:
Mehta V; Department of Cell Systems & Anatomy, University of Texas Health Science Center at San Antonio, Texas, 78229, USA.
Dwivedi AR; GITAM School of Pharmacy, GITAM (Deemed to be) University, Hyderabad, 502329, India.
Ludhiadch A; Department of Genetics and Development, Columbia University Irving Medical Center, New York, 10032, USA.
Rana V; School of Pharmacy, Graphic Era Hill University, Clement town, Dehradun, 248002, Uttarakhand, India.
Goel KK; Department of Pharmaceutical Sciences, Gurukul Kangri (Deemed to Be University), Haridwar, 249404, Uttarakhand, India.
Uniyal P; School of Pharmacy, Graphic Era Hill University, Clement town, Dehradun, 248002, Uttarakhand, India.
Joshi G; Department of Pharmaceutical Sciences, HNB Garhwal University, Chauras Campus, Garhwal, Srinagar, Uttarakhand, 246174, India; Department of Biotechnology, Graphic Era (Deemed to be University), Dehradun, 248002, Uttarakhand, India. Electronic address: .
Kumar A; Amity Institute of Pharmacy (AIP), Amity University Haryana, Panchgaon, Manesar, 122413, India. Electronic address: .
Kumar B; Department of Pharmaceutical Sciences, HNB Garhwal University, Chauras Campus, Garhwal, Srinagar, Uttarakhand, 246174, India. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Jan 05; Vol. 263, pp. 115942. Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Signal Transduction*
United States ; Humans ; United States Food and Drug Administration ; NF-kappa B/metabolism ; Inflammation/drug therapy ; Inflammation/metabolism
Czasopismo naukowe
Tytuł:
Synthesis and anti-inflammatory activity of novel firocoxib analogues with balanced COX inhibition.
Autorzy:
Xu J; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China.
Tang K; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China.
Ju Z; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2024 Jan; Vol. 103 (1), pp. e14437.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/chemistry
Sulfones*/pharmacology
4-Butyrolactone/*analogs & derivatives
Animals ; Mice ; Cyclooxygenase 2/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; NF-kappa B/metabolism ; Lipopolysaccharides/pharmacology ; Nitric Oxide/metabolism
Czasopismo naukowe
Tytuł:
Synthetic peptides of IL-1Ra and HSP70 have anti-inflammatory activity on human primary monocytes and macrophages: Potential treatments for inflammatory diseases.
Autorzy:
Pensado-López A; Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy. Electronic address: .
Ummarino A; Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, 20089, Milan, Italy. Electronic address: .
Khan S; Tissue Click Ltd, The Knoll Business Centre, Old Shoreham Rd, Hove, BN3 7GS, UK. Electronic address: .
Guildford A; Tissue Click Ltd, The Knoll Business Centre, Old Shoreham Rd, Hove, BN3 7GS, UK. Electronic address: .
Allan IU; Tissue Click Ltd, The Knoll Business Centre, Old Shoreham Rd, Hove, BN3 7GS, UK. Electronic address: .
Santin M; Centre for Regenerative Medicine and Devices, School of Applied Sciences, University of Brighton, Huxley Building Lewes Road, Brighton BN 24GJ, UK. Electronic address: .
Chevallier N; IMRB, U955, INSERM, Unite d'Ingenierie et de Therapie Cellulaire-Etablissement Français du Sang, Universite Paris-EST Créteil, 94017 Créteil, France. Electronic address: .
Varaillon E; IMRB, U955, INSERM, Unite d'Ingenierie et de Therapie Cellulaire-Etablissement Français du Sang, Universite Paris-EST Créteil, 94017 Créteil, France. Electronic address: .
Kon E; Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, 20089, Milan, Italy. Electronic address: .
Allavena P; IRCCS Humanitas Research Hospital, Rozzano, 20089, Milan, Italy. Electronic address: .
Torres Andón F; Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Milan, Italy; Instituto de Investigación Biomédica de A Coruña (INIBIC), Medical Oncology Unit, Complexo Hospitalario de A Coruña (CHUAC), 15006 A Coruña, Spain. Electronic address: .
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Źródło:
Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2024 Jan; Vol. 55, pp. 102719. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Interleukin 1 Receptor Antagonist Protein*/pharmacology
Interleukin 1 Receptor Antagonist Protein*/therapeutic use
Humans ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Monocytes/drug effects ; Peptides/pharmacology ; Peptides/therapeutic use
Czasopismo naukowe
Tytuł:
Decomposition of non-steroidal anti-inflammatory drugs by activated sludge supported by biopreparation in sequencing batch reactor.
Autorzy:
Dzionek A; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Science, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland. Electronic address: .
Nowak A; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Science, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland. Electronic address: .
Wojcieszyńska D; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Science, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland. Electronic address: .
Potocka I; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Science, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland. Electronic address: .
Smułek W; Institute of Chemical Technology and Engineering, Poznan University of Technology, Berdychowo 4, 60-965 Poznan, Poland. Electronic address: .
Guzik U; Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Science, University of Silesia in Katowice, Jagiellońska 28, 40-032 Katowice, Poland. Electronic address: .
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Źródło:
Bioresource technology [Bioresour Technol] 2024 Mar; Vol. 395, pp. 130328. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Sewage*/microbiology
Anti-Inflammatory Agents, Non-Steroidal*
Ibuprofen ; Diclofenac ; Naproxen
Czasopismo naukowe
Tytuł:
Pharmacokinetics of meloxicam in pre-ruminant calves after intravenous, oral, and subcutaneous administration.
Autorzy:
Jokela A; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Nyrhilä A; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Adam M; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Pharmacology Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Salla K; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Raekallio M; Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Aho R; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Norring M; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Hokkanen AH; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; Research Centre for Animal Welfare, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
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Źródło:
Journal of veterinary pharmacology and therapeutics [J Vet Pharmacol Ther] 2024 Mar; Vol. 47 (2), pp. 143-149. Date of Electronic Publication: 2023 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/pharmacokinetics
Thiazines*/pharmacokinetics
Cattle ; Animals ; Horses ; Meloxicam/therapeutic use ; Thiazoles/pharmacokinetics ; Half-Life ; Area Under Curve ; Pain/veterinary ; Administration, Oral ; Ruminants
Czasopismo naukowe
Tytuł:
Hybrids of selective COX-2 inhibitors and active derivatives of edaravone as COX-2 selective NSAIDs with free radical scavenging activity: Design, synthesis and biological activities.
Autorzy:
Wang Y; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Yang G; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Shen H; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Liang Y; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Dong H; The Public Laboratory Platform, China Pharmaceutical University, Nanjing, 210009, China.
Guo X; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Hao Q; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Wang J; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 15; Vol. 266, pp. 116155. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Cyclooxygenase 2 Inhibitors*/pharmacology
Mice ; Animals ; Edaravone/pharmacology ; Cyclooxygenase 2 ; Celecoxib ; Antioxidants ; Analgesics/pharmacology ; Free Radicals/chemistry
Czasopismo naukowe
Tytuł:
5+1-Heterocyclization as preparative approach for carboxy-containing triazolo[1,5-c]quinazolines with anti-inflammatory activity.
Autorzy:
Krasovska N; Community Company 'Prymula', Metalurgiv av, 7, Zaporizhzhia, 69032, Ukraine.
Berest G; Zaporizhzhia State Medical and Pharmaceutical University, 26 Mayakovski Av, Zaporizhzhia, 69035, Ukraine.
Belenichev I; Zaporizhzhia State Medical and Pharmaceutical University, 26 Mayakovski Av, Zaporizhzhia, 69035, Ukraine.
Severina H; National University of Pharmacy, Pushkinska str., 53, Kharkiv, 61002, Ukraine.
Nosulenko I; Zaporizhzhia State Medical and Pharmaceutical University, 26 Mayakovski Av, Zaporizhzhia, 69035, Ukraine.
Voskoboinik O; National University «Zaporizhzhia Polytechnic», Zhukovskyi st. 64, Zaporizhzhia, Ukraine. Electronic address: .
Okovytyy S; Oles Honchar Dnipro National University, 72, Gagarin Avenue, Dnipro, 49010, Ukraine.
Kovalenko S; Oles Honchar Dnipro National University, 72, Gagarin Avenue, Dnipro, 49010, Ukraine.
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 15; Vol. 266, pp. 116137. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents*/pharmacology
Quinazolines*/pharmacology
Quinazolines*/chemistry
Benzoic Acid ; Molecular Docking Simulation ; Structure-Activity Relationship ; Triazoles/chemistry ; Triazoles/pharmacology
Czasopismo naukowe
Tytuł:
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes.
Autorzy:
Elzahhar PA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Orioli R; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
Hassan NW; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Gobbi S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
Belluti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy.
Labib HF; Department of Pharmaceutical Chemistry, College of Pharmacy, Arab Academy of Science Technology and Maritime Transport, Alexandria, Egypt.
El-Yazbi AF; Faculty of Pharmacy and the Research and Innovation Hub, Alamein International University, Alamein, 5060335, Egypt; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Nassra R; Department of Medical Biochemistry, Faculty of Medicine, Alexandria University, Egypt.
Belal ASF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt. Electronic address: .
Bisi A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2024 Feb 15; Vol. 266, pp. 116138. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Lipoxygenase Inhibitors*/chemistry
Anti-Inflammatory Agents*/pharmacology
Rats ; Animals ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 1/metabolism ; Arachidonic Acids ; Edema/chemically induced ; Edema/drug therapy ; Molecular Docking Simulation ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase 2 Inhibitors/therapeutic use ; Arachidonate 5-Lipoxygenase/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Erdr1 Drives Macrophage Programming via Dynamic Interplay with YAP1 and Mid1.
Autorzy:
Wang Y; Department of Microbiology and Immunology, University of Iowa, IA City, IA.
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Źródło:
ImmunoHorizons [Immunohorizons] 2024 Feb 01; Vol. 8 (2), pp. 198-213.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Anti-Inflammatory Agents*
Humans ; Animals ; Mice ; Gene Expression ; Cytokines ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł:
Anti-Inflammatory and Antioxidant Pyrrolo[3,4- d ]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins-Spectroscopic and In Silico Studies.
Autorzy:
Kotynia A; Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Krzyżak E; Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Żądło J; 'Biomolecule' Student Science Club, Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Witczak M; 'Biomolecule' Student Science Club, Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
Szczukowski Ł; Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Mucha J; Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Świątek P; Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.
Marciniak A; Department of Basic Chemical Sciences, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211a, 50-556 Wrocław, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 01; Vol. 25 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*
Anti-Inflammatory Agents*
DNA/chemistry ; Models, Molecular ; Blood Proteins ; Molecular Docking Simulation
Czasopismo naukowe

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