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Wyszukujesz frazę ""Antibiotics, Antineoplastic"" wg kryterium: Temat


Tytuł :
Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum.
Autorzy :
Park SJ; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Lee EJ; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Lee HS; Interdisciplinary Program in Bioengineering, Seoul National University Graduate School, Seoul, Republic of Korea.
Kim J; Interdisciplinary Program in Bioengineering, Seoul National University Graduate School, Seoul, Republic of Korea.
Park S; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Ham J; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Mun J; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Paik H; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Lim H; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Seol A; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Yim GW; Department of Obstetrics and Gynecology, Dongguk University Ilsan Hospital, Goyang, Korea.
Shim SH; Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
Kang BC; Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Chang SJ; Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, Republic of Korea.
Lim W; Department of Food and Nutrition, Kookmin University, Seoul, Republic of Korea.
Song G; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Kim JW; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
Lee N; Department of Obstetrics & Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
Park JW; Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.
Lee JC; Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, Republic of Korea.; Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul, South Korea.
Kim HS; Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
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Corporate Authors :
KoRIA* trial group
Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1179-1187.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*administration & dosage
Antibiotics, Antineoplastic/*pharmacokinetics
Doxorubicin/*administration & dosage
Doxorubicin/*pharmacokinetics
Drug Delivery Systems/*methods
Peritoneum/*drug effects
Aerosols ; Animals ; Antibiotics, Antineoplastic/adverse effects ; Doxorubicin/adverse effects ; Swine
Czasopismo naukowe
Tytuł :
Tumor-targeted Gd-doped mesoporous Fe 3 O 4 nanoparticles for T 1 /T 2 MR imaging guided synergistic cancer therapy.
Autorzy :
Zheng S; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Jin S; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Jiao M; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.
Wang W; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.
Zhou X; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Xu J; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Wang Y; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Dou P; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.
Jin Z; College of Medical Engineering, Xinxiang Key Laboratory of Neurobiosensor, Xinxiang Medical University, Xinxiang, Henan , China.
Wu C; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Li J; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
Ge X; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; School of Information Science and Engineering, Shandong Normal University, Jinan, China.
Xu K; School of Medical Imaging, Xuzhou Medical University, Xuzhou, China.; Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.; Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou, China.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 787-799.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*administration & dosage
Doxorubicin/*administration & dosage
Magnetic Iron Oxide Nanoparticles/*chemistry
Magnetic Resonance Imaging, Interventional/*methods
Neoplasms/*drug therapy
Animals ; Antibiotics, Antineoplastic/pharmacology ; Cell Line, Tumor ; Contrast Media/chemistry ; Doxorubicin/pharmacology ; Drug Carriers ; Drug Delivery Systems ; Drug Liberation ; Gadolinium/chemistry ; Mice
Czasopismo naukowe
Tytuł :
Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging.
Autorzy :
Hendel K; Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Hansen ACN; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Bik L; Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.; Department of Dermatology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Bagger C; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
van Doorn MBA; Department of Dermatology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Janfelt C; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Olesen UH; Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Haedersdal M; Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Lerche CM; Department of Dermatology, Copenhagen University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1141-1149.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacokinetics
Bleomycin/*pharmacokinetics
Electroporation/*methods
Injections, Intradermal/*methods
Lasers, Gas/*therapeutic use
Administration, Cutaneous ; Animals ; Antibiotics, Antineoplastic/administration & dosage ; Bleomycin/administration & dosage ; Female ; Injections, Intradermal/adverse effects ; Lasers, Gas/adverse effects ; Mass Spectrometry ; Skin/metabolism ; Skin Absorption ; Swine
Czasopismo naukowe
Tytuł :
Lipid bubbles combined with low-intensity ultrasound enhance the intratumoral accumulation and antitumor effect of pegylated liposomal doxorubicin in vivo .
Autorzy :
Yokoe I; Faculty of Agriculture, Joint Department of Veterinary Clinical Medicine, Tottori University, Tottori, Japan.
Omata D; Faculty of Pharma-Science, Laboratory of Drug and Gene Delivery Research, Teikyo University, Tokyo, Japan.
Unga J; Faculty of Pharma-Science, Laboratory of Drug and Gene Delivery Research, Teikyo University, Tokyo, Japan.
Suzuki R; Faculty of Pharma-Science, Laboratory of Drug and Gene Delivery Research, Teikyo University, Tokyo, Japan.
Maruyama K; Faculty of Pharma-Science, Laboratory of Theranostics, Teikyo University, Tokyo, Japan.
Okamoto Y; Faculty of Agriculture, Joint Department of Veterinary Clinical Medicine, Tottori University, Tottori, Japan.
Osaki T; Faculty of Agriculture, Joint Department of Veterinary Clinical Medicine, Tottori University, Tottori, Japan.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 530-541.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Drug Delivery Systems*
Microbubbles*
Antibiotics, Antineoplastic/*administration & dosage
Doxorubicin/*analogs & derivatives
Animals ; Antibiotics, Antineoplastic/pharmacology ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacology ; Female ; Lipids/chemistry ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Inbred BALB C ; Polyethylene Glycols/administration & dosage ; Polyethylene Glycols/pharmacology ; Ultrasonic Waves
Czasopismo naukowe
Tytuł :
Ideal Nozzle Position During Pressurized Intraperitoneal Aerosol Chemotherapy in an Ex Vivo Model.
Autorzy :
Piao J; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Park SJ; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Lee H; Interdisciplinary Program in Bioengineering, Seoul National University Graduate School, Seoul, Republic of Korea.
Kim J; Interdisciplinary Program in Bioengineering, Seoul National University Graduate School, Seoul, Republic of Korea.
Park S; Department of Plant & Biomaterials Science, Gyeongsang National University, Jinju-si, Republic of Korea.
Lee N; Department of Obstetrics & Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, Republic of Korea.
Kim SI; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Lee M; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.
Song G; Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Lee JC; Department of Biomedical Engineering, Seoul National University College of Medicine, and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul, Republic of Korea.
Kim HS; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea; .
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Corporate Authors :
KORIA TRIAL GROUP
Źródło :
Anticancer research [Anticancer Res] 2021 Nov; Vol. 41 (11), pp. 5489-5498.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*administration & dosage
Antineoplastic Agents/*administration & dosage
Doxorubicin/*administration & dosage
Drug Delivery Systems/*instrumentation
Peritoneal Neoplasms/*drug therapy
Peritoneum/*metabolism
Aerosols ; Animals ; Antibiotics, Antineoplastic/metabolism ; Antineoplastic Agents/metabolism ; Diffusion ; Doxorubicin/metabolism ; Equipment Design ; Pressure ; Sus scrofa ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Doxorubicin-loaded natural daptomycin micelles with enhanced targeting and anti-tumor effect in vivo.
Autorzy :
Guo Q; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China; State Key Laboratory of Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, China.
Zhang L; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China.
He M; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China.
Jiang X; Hebei Key Laboratory for Chronic Diseases, School of Basic Medicine, North China University of Science and Technology, Tangshan, 063210, China.
Tian J; Hebei Key Laboratory for Chronic Diseases, School of Basic Medicine, North China University of Science and Technology, Tangshan, 063210, China.
Li Q; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China.
Liu Z; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China.
Wang L; Key Laboratory of Applied Chemistry, Hebei Key Laboratory of Heavy Metal Deep-remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, China; State Key Laboratory of Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, China. Electronic address: .
Sun H; Ocean NanoTech, LLC, San Diego, CA, 92126, USA. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 15; Vol. 222, pp. 113582. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antibiotics, Antineoplastic/*pharmacology
Biological Products/*pharmacology
Daptomycin/*pharmacology
Doxorubicin/*pharmacology
Animals ; Anti-Bacterial Agents/chemistry ; Antibiotics, Antineoplastic/chemistry ; Biological Products/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Daptomycin/chemistry ; Dose-Response Relationship, Drug ; Doxorubicin/chemistry ; Drug Screening Assays, Antitumor ; Escherichia coli/drug effects ; Humans ; Mice ; Micelles ; Molecular Structure ; Staphylococcus aureus/drug effects ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
The prognosis of cancer patients undergoing liposomal doxorubicin-based chemotherapy: A systematic review and meta-analysis.
Autorzy :
Zhang KP; Department of Urology, Anhui Provincial Children's Hospital and Children's Hospital of Anhui Medical University, Hefei, Anhui, P. R. China.
Fang X
Zhang Y
Chao M
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Aug 27; Vol. 100 (34), pp. e26690.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Antibiotics, Antineoplastic/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Doxorubicin/*analogs & derivatives
Neoplasms/*drug therapy
Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/adverse effects ; Doxorubicin/administration & dosage ; Doxorubicin/adverse effects ; Doxorubicin/therapeutic use ; Humans ; Multicenter Studies as Topic ; Polyethylene Glycols/administration & dosage ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/therapeutic use ; Proportional Hazards Models ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł :
Next generation risk assessment (NGRA): Bridging in vitro points-of-departure to human safety assessment using physiologically-based kinetic (PBK) modelling - A case study of doxorubicin with dose metrics considerations.
Autorzy :
Li H; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Yuan H; Evaluation and Research Centre for Toxicology, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China.
Middleton A; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Li J; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Nicol B; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Carmichael P; Unilever Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Guo J; Evaluation and Research Centre for Toxicology, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China.
Peng S; Evaluation and Research Centre for Toxicology, Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071, China. Electronic address: .
Zhang Q; Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA. Electronic address: .
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2021 Aug; Vol. 74, pp. 105171. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Antibiotics, Antineoplastic/*pharmacokinetics
Doxorubicin/*pharmacokinetics
Risk Assessment/*methods
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/blood ; Cell Line ; Doxorubicin/administration & dosage ; Doxorubicin/blood ; Female ; Humans ; Male ; Middle Aged ; Myocardium/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Zealpeptaibolin, an 11-mer cytotoxic peptaibol group with 3 Aib-Pro motifs isolated from Trichoderma sp. RK10-F026.
Autorzy :
Rawa MSA; Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan.; School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia.
Nogawa T; Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan.
Okano A; Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan.
Futamura Y; Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan.
Wahab HA; School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia.
Osada H; Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science, Saitama, Japan. .
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Źródło :
The Journal of antibiotics [J Antibiot (Tokyo)] 2021 Aug; Vol. 74 (8), pp. 485-495. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibiotics, Antineoplastic/*chemistry
Trichoderma/*metabolism
Animals ; Antibiotics, Antineoplastic/biosynthesis ; Antibiotics, Antineoplastic/pharmacology ; Antimalarials/pharmacology ; Cell Line, Tumor ; Culture Media ; Fermentation ; Humans ; K562 Cells ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Plasmodium falciparum/drug effects ; Soil Microbiology ; Spectrometry, Mass, Electrospray Ionization
Czasopismo naukowe
Tytuł :
Hybrid nanoparticles based on ortho ester-modified pluronic L61 and chitosan for efficient doxorubicin delivery.
Autorzy :
Xu X; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Xue Y; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Fang Q; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Qiao Z; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Liu S; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Wang X; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China.
Tang R; Engineering Research Center for Biomedical Materials, Anhui Key Laboratory of Modern Biomanufacturing, School of Life Sciences, Anhui University, 111 Jiulong Road, Hefei, Anhui Province 230601, PR China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 1596-1606. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*administration & dosage
Chitosan/*chemistry
Doxorubicin/*administration & dosage
Liver Neoplasms/*drug therapy
Poloxamer/*chemistry
Animals ; Antibiotics, Antineoplastic/chemistry ; Antibiotics, Antineoplastic/pharmacology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Doxorubicin/chemistry ; Doxorubicin/pharmacology ; Drug Carriers ; Dynamic Light Scattering ; Esters ; Hep G2 Cells ; Humans ; Hydrogen-Ion Concentration ; Male ; Mice ; Microscopy, Electron, Scanning ; Nanoparticles ; Particle Size ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
A chitosan/mesoporous silica nanoparticle-based anticancer drug delivery system with a "tumor-triggered targeting" property.
Autorzy :
Liao T; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China.
Liu C; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China.
Ren J; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China.
Chen H; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China.
Kuang Y; Glyn O. Philips Hydrocolloid Research Centre at HUT, Hubei University of Technology, Wuhan, Hubei 430068, China.
Jiang B; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China.
Chen J; Shimadzu (China) Co., Ltd., Wuhan 430060, China.
Sun Z; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China. Electronic address: .
Li C; Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, Hubei University, Wuhan 430062, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 2017-2029. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Carriers*
Nanoparticles*
Antibiotics, Antineoplastic/*pharmacology
Breast Neoplasms/*drug therapy
Chitosan/*chemistry
Silicates/*chemistry
beta-Cyclodextrins/*chemistry
Adamantane/chemistry ; Animals ; Antibiotics, Antineoplastic/chemistry ; Antibiotics, Antineoplastic/metabolism ; Benzimidazoles/chemistry ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Delayed-Action Preparations ; Doxorubicin/chemistry ; Doxorubicin/metabolism ; Doxorubicin/pharmacology ; Drug Compounding ; Female ; Hydrogen-Ion Concentration ; Mice ; Mice, Inbred BALB C ; Oligopeptides/chemistry ; Oligopeptides/metabolism ; Polyethylene Glycols/chemistry ; Porosity ; Tumor Burden/drug effects
Czasopismo naukowe
Tytuł :
A Cyanine-Mediated Self-Assembly System for the Construction of a Two-in-One Nanodrug.
Autorzy :
Wang H; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
Xiao H; State Key Laboratory of Structure of Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, 350002, P. R. China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhu X; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
Liu Y; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
Fu Z; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
Li C; State Key Laboratory of Structure of Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, 350002, P. R. China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Lu C; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
Yang H; MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, 350116, P. R. China.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Sep 20; Vol. 60 (39), pp. 21226-21230. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacology
Carbocyanines/*chemistry
DNA/*chemistry
Doxorubicin/*pharmacology
Nanoparticles/*chemistry
Oligonucleotides, Antisense/*pharmacology
Antibiotics, Antineoplastic/chemistry ; Cell Line, Tumor ; Cell Survival/drug effects ; Doxorubicin/chemistry ; Drug Screening Assays, Antitumor ; Humans ; Molecular Dynamics Simulation ; Oligonucleotides, Antisense/chemistry ; Particle Size
Czasopismo naukowe
Tytuł :
Nanomediator-Effector Cascade Systems for Amplified Protein Kinase Activity Imaging and Phosphorylation-Induced Drug Release In Vivo.
Autorzy :
Zheng F; State Key Laboratory of Analytical Chemistry for life Science, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.; School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212003, China.
Meng T; State Key Laboratory of Analytical Chemistry for life Science, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Jiang D; School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212003, China.
Sun J; School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212003, China.
Yao H; School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, 212003, China.
Zhu JJ; State Key Laboratory of Analytical Chemistry for life Science, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
Min Q; State Key Laboratory of Analytical Chemistry for life Science, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Sep 20; Vol. 60 (39), pp. 21565-21574. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Nucleic Acid Amplification Techniques*
Antibiotics, Antineoplastic/*pharmacology
DNA/*chemistry
Doxorubicin/*pharmacology
Nanoparticles/*chemistry
Peptides/*chemistry
Protein Kinases/*metabolism
Antibiotics, Antineoplastic/chemistry ; Cell Line ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; DNA/metabolism ; Doxorubicin/chemistry ; Drug Delivery Systems ; Drug Liberation ; Humans ; Nanoparticles/metabolism ; Nucleic Acid Hybridization ; Optical Imaging ; Peptides/metabolism ; Phosphorylation ; Protein Kinases/analysis
Czasopismo naukowe
Tytuł :
Doxorubicin Paradoxically Ameliorates Tumor-Induced Inflammation in Young Mice.
Autorzy :
Abdelgawad IY; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Grant MKO; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Popescu FE; Department of Pediatrics, Genetics, Cell Biology and Development, Masonic Cancer Center, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.
Largaespada DA; Department of Pediatrics, Genetics, Cell Biology and Development, Masonic Cancer Center, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.
Zordoky BN; Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 21; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*therapeutic use
Doxorubicin/*therapeutic use
Inflammation/*drug therapy
Lymphoma/*drug therapy
Animals ; Antibiotics, Antineoplastic/pharmacology ; Biomarkers/metabolism ; Cell Line, Tumor ; Cytokines/blood ; Doxorubicin/pharmacology ; Drug Screening Assays, Antitumor ; Heart/drug effects ; Inflammation/blood ; Inflammation/etiology ; Kidney/drug effects ; Kidney/metabolism ; Liver/drug effects ; Liver/metabolism ; Lymphoma/complications ; Male ; Mice ; Mice, Inbred C57BL ; Myocardium/metabolism
Czasopismo naukowe
Tytuł :
Cytosine-Rich DNA Fragments Covalently Bound to Carbon Nanotube as Factors Triggering Doxorubicin Release at Acidic pH. A Molecular Dynamics Study.
Autorzy :
Wolski P; Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, ul. Niezapominajek 8, 30239 Cracow, Poland.
Nieszporek K; Department of Theoretical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, pl. Maria Curie-Sklodowska 3, 20031 Lublin, Poland.
Panczyk T; Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, ul. Niezapominajek 8, 30239 Cracow, Poland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 06; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*administration & dosage
Cytosine/*analogs & derivatives
Delayed-Action Preparations/*chemistry
Doxorubicin/*administration & dosage
Nanotubes, Carbon/*chemistry
Antibiotics, Antineoplastic/chemistry ; DNA/chemistry ; Doxorubicin/chemistry ; Drug Liberation ; Hydrogen-Ion Concentration ; Molecular Dynamics Simulation
Czasopismo naukowe
Tytuł :
Resveratrol significantly improves cell survival in comparison to dexrazoxane and carvedilol in a h9c2 model of doxorubicin induced cardiotoxicity.
Autorzy :
Monahan DS; Anatomy & Regenerative Medicine Institute, School of Medicine, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland; Centre for Research in Medical Devices (CύRAM), National University of Ireland Galway, Galway, Ireland. Electronic address: .
Flaherty E; Anatomy & Regenerative Medicine Institute, School of Medicine, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland. Electronic address: .
Hameed A; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, Dublin 2, Dublin, Ireland; Trinity Centre for Biomedical Engineering (TCBE), Trinity College Dublin (TCD), Dublin, Ireland. Electronic address: .
Duffy GP; Anatomy & Regenerative Medicine Institute, School of Medicine, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland; Centre for Research in Medical Devices (CύRAM), National University of Ireland Galway, Galway, Ireland; Tissue Engineering Research Group (TERG), Department of Anatomy and Regenerative Medicine, RCSI University of Medicine and Health Sciences, Dublin 2, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Trinity College Dublin & National University of Ireland Galway, Ireland. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111702. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antibiotics, Antineoplastic*
Doxorubicin*
Cardiotonic Agents/*pharmacology
Cardiotoxicity/*drug therapy
Resveratrol/*pharmacology
Animals ; Carvedilol/pharmacology ; Cell Line ; Cell Survival/drug effects ; Dexrazoxane/pharmacology ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Rice starch coated iron oxide nanoparticles: A theranostic probe for photoacoustic imaging-guided photothermal cancer therapy.
Autorzy :
Vo TMT; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Mondal S; New-senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, Republic of Korea.
Nguyen VT; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Park S; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Choi J; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Bui NT; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Oh J; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea; New-senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, Republic of Korea; Ohlabs Corp., Busan 48513, Republic of Korea; Department of Biomedical Engineering, Pukyong National University, Busan 48513, Republic of Korea. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 55-67. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Oryza*/chemistry
Photoacoustic Techniques*
Photothermal Therapy*
Theranostic Nanomedicine*
Antibiotics, Antineoplastic/*pharmacology
Bone Neoplasms/*therapy
Doxorubicin/*pharmacology
Magnetic Iron Oxide Nanoparticles/*chemistry
Osteosarcoma/*therapy
Starch/*pharmacology
Antibiotics, Antineoplastic/chemistry ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/metabolism ; Cell Line, Tumor ; Delayed-Action Preparations ; Doxorubicin/chemistry ; Drug Carriers ; Drug Liberation ; Humans ; Hydrogen-Ion Concentration ; Kinetics ; Osteosarcoma/diagnostic imaging ; Osteosarcoma/metabolism ; Starch/isolation & purification
Czasopismo naukowe
Tytuł :
Step-by-Step Design of New Theranostic Nanoformulations: Multifunctional Nanovectors for Radio-Chemo-Hyperthermic Therapy under Physical Targeting.
Autorzy :
Ansari SA; Department of Neurosciences, University of Turin, 10124 Turin, Italy.
Ficiarà E; Department of Neurosciences, University of Turin, 10124 Turin, Italy.
D'Agata F; Department of Neurosciences, University of Turin, 10124 Turin, Italy.
Cavalli R; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy.
Nasi L; IMEM CNR, Parco Area delle Scienze 37/A, 43124 Parma, Italy.
Casoli F; IMEM CNR, Parco Area delle Scienze 37/A, 43124 Parma, Italy.
Albertini F; IMEM CNR, Parco Area delle Scienze 37/A, 43124 Parma, Italy.
Guiot C; Department of Neurosciences, University of Turin, 10124 Turin, Italy.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 29; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacology
Chitosan/*chemistry
Hyperthermia, Induced/*methods
Magnetite Nanoparticles/*chemistry
Radiation-Sensitizing Agents/*pharmacology
Theranostic Nanomedicine/*methods
Antibiotics, Antineoplastic/chemistry ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Contrast Media/chemical synthesis ; Contrast Media/pharmacology ; Curcumin/chemistry ; Curcumin/pharmacology ; Dextran Sulfate/chemistry ; Doxorubicin/chemistry ; Doxorubicin/pharmacology ; Drug Compounding/methods ; Humans ; Kinetics ; Magnetite Nanoparticles/ultrastructure ; Oxygen/chemistry ; Oxygen/pharmacology ; Radiation-Sensitizing Agents/chemical synthesis
Czasopismo naukowe
Tytuł :
In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma.
Autorzy :
Kullenberg F; Department of Pharmaceutical Biosciences, Uppsala University, 75 123 Uppsala, Sweden.
Degerstedt O; Department of Pharmaceutical Biosciences, Uppsala University, 75 123 Uppsala, Sweden.
Calitz C; Department of Medical Cell Biology, Uppsala University, 75 123 Uppsala, Sweden.
Pavlović N; Department of Medical Cell Biology, Uppsala University, 75 123 Uppsala, Sweden.
Balgoma D; Department of Medicinal Chemistry, Uppsala University, 75 123 Uppsala, Sweden.
Gråsjö J; Department of Pharmaceutical Biosciences, Uppsala University, 75 123 Uppsala, Sweden.; Department of Medicinal Chemistry, Uppsala University, 75 123 Uppsala, Sweden.
Sjögren E; Department of Pharmaceutical Biosciences, Uppsala University, 75 123 Uppsala, Sweden.
Hedeland M; Department of Medicinal Chemistry, Uppsala University, 75 123 Uppsala, Sweden.
Heindryckx F; Department of Medical Cell Biology, Uppsala University, 75 123 Uppsala, Sweden.
Lennernäs H; Department of Pharmaceutical Biosciences, Uppsala University, 75 123 Uppsala, Sweden.
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Źródło :
Cells [Cells] 2021 Jul 06; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacokinetics
Doxorubicin/*analogs & derivatives
Doxorubicin/*pharmacokinetics
Liposomes/*chemistry
Antibiotics, Antineoplastic/pharmacology ; Biological Availability ; Biological Transport ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Doxorubicin/pharmacology ; Drug Carriers ; Hep G2 Cells ; Humans ; Inhibitory Concentration 50 ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; MCF-7 Cells ; Models, Biological ; Models, Statistical ; Polyethylene Glycols/pharmacokinetics ; Polyethylene Glycols/pharmacology
Czasopismo naukowe
Tytuł :
Doxorubicin-Bound Hydroxyethyl Starch Conjugate Nanoparticles with pH/Redox Responsive Linkage for Enhancing Antitumor Therapy.
Autorzy :
Tan R; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People's Republic of China.
Tian D; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People's Republic of China.
Liu J; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People's Republic of China.
Wang C; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People's Republic of China.
Wan Y; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People's Republic of China.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Jul 05; Vol. 16, pp. 4527-4544. Date of Electronic Publication: 2021 Jul 05 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacology
Doxorubicin/*pharmacology
Drug Delivery Systems/*methods
Hydroxyethyl Starch Derivatives/*chemistry
Nanoparticles/*administration & dosage
Neoplasms/*drug therapy
Animals ; Antibiotics, Antineoplastic/chemistry ; Apoptosis ; Cell Proliferation ; Disulfides/chemistry ; Doxorubicin/chemistry ; Drug Liberation ; Humans ; Hydrogen-Ion Concentration ; Male ; Mice ; Mice, Inbred BALB C ; Nanoparticles/chemistry ; Neoplasms/pathology ; Oxidation-Reduction ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe

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