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Tytuł:
Anthracyclines induce cardiotoxicity through a shared gene expression response signature.
Autorzy:
Matthews ER; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Johnson OD; Biochemistry, Cellular and Molecular Biology Graduate Program, University of Texas Medical Branch, Galveston, Texas, United States of America.
Horn KJ; John Sealy School of Medicine, University of Texas Medical Branch, Galveston, Texas, United States of America.
Gutiérrez JA; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
Powell SR; Neuroscience Graduate Program, University of Texas Medical Branch, Galveston, Texas, United States of America.
Ward MC; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2024 Feb 28; Vol. 20 (2), pp. e1011164. Date of Electronic Publication: 2024 Feb 28 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Anthracyclines*/adverse effects
Anthracyclines*/metabolism
Cardiotoxicity*/genetics
Cardiotoxicity*/metabolism
Humans ; Female ; Antibiotics, Antineoplastic/adverse effects ; Antibiotics, Antineoplastic/metabolism ; Topoisomerase II Inhibitors/metabolism ; Topoisomerase II Inhibitors/pharmacology ; Doxorubicin/adverse effects ; Doxorubicin/metabolism ; Mitoxantrone/adverse effects ; Mitoxantrone/metabolism ; Myocytes, Cardiac/metabolism ; Daunorubicin/metabolism ; Daunorubicin/pharmacology ; Epirubicin/metabolism ; Epirubicin/pharmacology ; DNA Topoisomerases, Type II/genetics ; Gene Expression
Czasopismo naukowe
Tytuł:
Long-term survival after neoadjuvant therapy for triple-negative breast cancer under different treatment regimens: a systematic review and network meta-analysis.
Autorzy:
Liu Z; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Li J; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Zhao F; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Ren D; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Li Z; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Chen Y; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Huang S; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Liu Z; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Zhao Y; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Wang M; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China.
Li H; Department of Breast Medical Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Xu Z; Qinghai University, Xining, China.
Shen G; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China. .
Zhao J; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Affiliated Cancer Hospital of Qinghai University, People's Republic of China, Qinghai Provincial Clinical Research Center for Cancer, Qinghai Provincial Institute of Cancer Research, Xining, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Apr 09; Vol. 24 (1), pp. 440. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/pathology
Humans ; Neoadjuvant Therapy ; Network Meta-Analysis ; Taxoids/therapeutic use ; Cyclophosphamide/therapeutic use ; Antibiotics, Antineoplastic/therapeutic use ; Anthracyclines/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Czasopismo naukowe
Tytuł:
Patient-reported outcomes and symptom clusters pattern of chemotherapy-induced toxicity in patients with early breast cancer.
Autorzy:
Wiranata JA; Clinical Epidemiology Study Program, Master of Clinical Medicine Postgraduate Program, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Academic Hospital, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Hutajulu SH; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Astari YK; Research Scholar, Division of Hematology and Medical Oncology, Department of Internal Medicine, Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Leo B; Specialty Program in Internal Medicine, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Bintoro BS; Department of Health Behaviour, Environment, and Social Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Center of Health Behaviour and Promotion, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Hardianti MS; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Taroeno-Hariadi KW; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Kurnianda J; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
Purwanto I; Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
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Źródło:
PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0298928. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Humans ; Middle Aged ; Female ; Syndrome ; Antibiotics, Antineoplastic/therapeutic use ; Chemotherapy, Adjuvant/adverse effects ; Pain/drug therapy ; Patient Reported Outcome Measures
Czasopismo naukowe
Tytuł:
Assessment of the Impact of Carvedilol Administered Together with Dexrazoxan and Doxorubicin on Liver Structure and Function, Iron Metabolism, and Myocardial Redox System in Rats.
Autorzy:
Szponar J; Toxicology Clinic, Faculty of Medicine, Medical University of Lublin, 100 Krasnik Avenue, 20-550 Lublin, Poland.; Clinical Department of Toxicology and Cardiology, Stefan Wyszynski Regional Specialist Hospital, 100 Krasnik Avenue, 20-550 Lublin, Poland.
Gorska A; Toxicology Clinic, Faculty of Medicine, Medical University of Lublin, 100 Krasnik Avenue, 20-550 Lublin, Poland.; Clinical Department of Toxicology and Cardiology, Stefan Wyszynski Regional Specialist Hospital, 100 Krasnik Avenue, 20-550 Lublin, Poland.
Ostrowska-Lesko M; Department of Toxicology, Medical University of Lublin, 8b Jaczewski Street, 20-090 Lublin, Poland.
Korga-Plewko A; Independent Medical Biology Unit, Medical University, 8b Jaczewski Street, 20-090 Lublin, Poland.
Tchorz M; Toxicology Clinic, Faculty of Medicine, Medical University of Lublin, 100 Krasnik Avenue, 20-550 Lublin, Poland.; Clinical Department of Toxicology and Cardiology, Stefan Wyszynski Regional Specialist Hospital, 100 Krasnik Avenue, 20-550 Lublin, Poland.
Ciechanski E; Department of Toxicology, Medical University of Lublin, 8b Jaczewski Street, 20-090 Lublin, Poland.; Clinical Department of Cardiology, Stefan Wyszynski Regional Specialist Hospital, 100 Krasnik Avenue, 20-550 Lublin, Poland.
Dabrowska A; Department of Toxicology, Medical University of Lublin, 8b Jaczewski Street, 20-090 Lublin, Poland.
Poleszak E; Department of Applied Pharmacy, Medical University of Lublin, 1 Chodźko Street, 20-093 Lublin, Poland.
Burdan F; Human Anatomy Department, Medical University of Lublin, 4 Jaczewski Street, 20-090 Lublin, Poland.
Dudka J; Department of Toxicology, Medical University of Lublin, 8b Jaczewski Street, 20-090 Lublin, Poland.
Murias M; Department of Toxicology, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-608 Poznan, Poland.
Mandziuk S; Department of Pneumology, Oncology and Allergology, Medical University of Lublin, 8 Jaczewski Street, 20-090 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiotoxicity*/metabolism
Ascites*/pathology
Rats ; Animals ; Carvedilol/pharmacology ; NADP/metabolism ; Doxorubicin/therapeutic use ; Myocardium/metabolism ; Antibiotics, Antineoplastic/therapeutic use ; Iron/metabolism ; Lipid Peroxidation ; Liver/metabolism ; Transferrin/metabolism ; Body Weight
Czasopismo naukowe
Tytuł:
Anthracycline-induced cardiotoxicity on regional myocardial work and left ventricular mechanical dispersion in adolescents and young adults in post-lymphoma remission.
Autorzy:
Jaber M; CHU Clermont-Ferrand, Pédiatrie Générale, Clermont-Ferrand, France.
Armand A; CHU de Clermont-Ferrand, Service Hématologie Oncologie Pédiatrique, Clermont-Ferrand, France.
Rochette E; CHU Clermont-Ferrand, Pédiatrie Générale, Clermont-Ferrand, France.; Université Clermont Auvergne, INSERM, CIC 1405, CRECHE Unit, Clermont-Ferrand, France.
Monzy S; Cardiologue libéral, Pôle Santé République, Clermont-Ferrand, France.
Greze V; CHU de Clermont-Ferrand, Service Hématologie Oncologie Pédiatrique, Clermont-Ferrand, France.; Université Clermont Auvergne, INSERM, CIC 1405, CRECHE Unit, Clermont-Ferrand, France.
Kanold J; CHU de Clermont-Ferrand, Service Hématologie Oncologie Pédiatrique, Clermont-Ferrand, France.; Université Clermont Auvergne, INSERM, CIC 1405, CRECHE Unit, Clermont-Ferrand, France.
Merlin E; CHU Clermont-Ferrand, Pédiatrie Générale, Clermont-Ferrand, France.; CHU de Clermont-Ferrand, Service Hématologie Oncologie Pédiatrique, Clermont-Ferrand, France.
Paysal J; CHU de Clermont-Ferrand, Service Hématologie Oncologie Pédiatrique, Clermont-Ferrand, France.; CHU Clermont-Ferrand, Néonatologie et Réanimation Pédiatrique, Clermont-Ferrand, France.
Nottin S; Laboratory of Cardiovascular Adaptations to Exercise, Avignon, France.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (3), pp. e6857. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Lymphoma*
Polyketides*
Humans ; Adolescent ; Young Adult ; Cardiotoxicity/etiology ; Anthracyclines/adverse effects ; Myocardium ; Heart ; Antibiotics, Antineoplastic
Czasopismo naukowe
Tytuł:
Doxorubicin-Mediated miR-433 Expression on Exosomes Promotes Bystander Senescence in Multiple Myeloma Cells in a DDR-Independent Manner.
Autorzy:
Vulpis E; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Cuollo L; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Borrelli C; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Antonangeli F; Institute of Molecular Biology and Pathology, National Research Council (CNR), 00161 Rome, Italy.
Masuelli L; Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Cippitelli M; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Fionda C; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Caracciolo G; Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Petrucci MT; Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, 00161 Rome, Italy.
Santoni A; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.; IRCCS Neuromed, 86077 Pozzilli, Italy.
Zingoni A; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
Soriani A; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Viale Regina Elena 291, 00161 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cellular Senescence*/drug effects
Bystander Effect*
Multiple Myeloma*/drug therapy
Multiple Myeloma*/genetics
Multiple Myeloma*/pathology
Doxorubicin*/pharmacology
Doxorubicin*/therapeutic use
Antibiotics, Antineoplastic*/pharmacology
Antibiotics, Antineoplastic*/therapeutic use
Topoisomerase II Inhibitors*/pharmacology
Topoisomerase II Inhibitors*/therapeutic use
Exosomes*/drug effects
Exosomes*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; Cell Line, Tumor ; DNA Damage ; Tumor Suppressor Protein p53/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism
Czasopismo naukowe
Tytuł:
Rethinking Biosynthesis of Aclacinomycin A.
Autorzy:
Xu Z; Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Tian P; Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 18; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aclarubicin*
Antibiotics, Antineoplastic*
Fermentation ; Biosynthetic Pathways ; Metabolic Engineering
Czasopismo naukowe
Tytuł:
Comprehensive Analysis of Transcriptomics and Genetic Alterations Identifies Potential Mechanisms Underlying Anthracycline Therapy Resistance in Breast Cancer.
Autorzy:
Liu Z; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.; Department of Breast and Thyroid Surgery, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Gao J; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Gu R; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Shi Y; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Hu H; Department of Breast and Thyroid Surgery, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Liu J; Department of Pathology, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Huang J; Department of Breast and Thyroid Surgery, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Zhong C; Department of Breast and Thyroid Surgery, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Zhou W; Department of Breast and Thyroid Surgery, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen 518020, China.
Yang Y; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Gong C; Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
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Źródło:
Biomolecules [Biomolecules] 2022 Dec 08; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anthracyclines*/pharmacology
Anthracyclines*/therapeutic use
Antibiotics, Antineoplastic*/pharmacology
Antibiotics, Antineoplastic*/therapeutic use
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Drug Resistance, Neoplasm*/genetics
Transcriptome*
Gene Expression Profiling*
Female ; Humans ; Cytochrome P450 Family 4/genetics ; Mutation
Czasopismo naukowe
Tytuł:
Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy.
Autorzy:
He P; Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xu S; Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Guo Z; Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yuan P; Department of Orthopedics, Fuyang Hospital of Anhui Medical University, Fuyang, China.
Liu Y; Department of Orthopedics, Fuyang Hospital of Anhui Medical University, Fuyang, China.
Chen Y; Department of Pharmacy, Anqing Medical College, Anqing, China.
Zhang T; Laboratory of Pharmaceutical Research, Anhui Zhongren Science and Technology Co., Ltd, Hefei, China.
Que Y; Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Hu Y; Department of Orthopedics, First Affiliated Hospital of Anhui Medical University, Hefei, China.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 478-488.
Typ publikacji:
Journal Article
MeSH Terms:
Antibiotics, Antineoplastic/*pharmacology
Bone Neoplasms/*pathology
Doxorubicin/*pharmacology
Drug Implants/*chemistry
Osteosarcoma/*pathology
Animals ; Animals, Outbred Strains ; Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/pharmacokinetics ; Cell Line, Tumor ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacokinetics ; Drug Liberation ; Female ; Male ; Mice ; Mice, Inbred BALB C ; Polyethylene Glycols/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Random Allocation ; Rats, Sprague-Dawley ; Technology, Pharmaceutical ; Xenograft Model Antitumor Assays ; Rats
SCR Organism:
Kunming mice
Czasopismo naukowe
Tytuł:
Synergic fabrication of multifunctional liposomes nanocomposites for improved radiofrequency ablation combination for liver metastasis cancer therapy.
Autorzy:
Zhang N; Department of Hepatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Wu Y; Department of Hepatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Xu W; Department of Hepatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Li Z; 3D Biomedicine Science & Technology Co., Limited, Shanghai, China.
Wang L; Department of Hepatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 506-518.
Typ publikacji:
Journal Article
MeSH Terms:
Antibiotics, Antineoplastic/*pharmacology
Doxorubicin/*pharmacology
Liposomes/*chemistry
Liver Neoplasms/*pathology
Radiofrequency Ablation/*methods
Animals ; Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/pharmacokinetics ; Apoptosis/drug effects ; Chemistry, Pharmaceutical ; Colonic Neoplasms/pathology ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacokinetics ; Drug Carriers/chemistry ; Drug Liberation ; Fullerenes/chemistry ; Liver Neoplasms/secondary ; Metal Nanoparticles/chemistry ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Nanoparticles/chemistry ; Particle Size ; Polyethylene Glycols/chemistry ; Surface Properties ; Tumor Burden/drug effects
Czasopismo naukowe
Tytuł:
Resistance to Combined Anthracycline-Taxane Chemotherapy Is Associated with Altered Metabolism and Inflammation in Breast Carcinomas.
Autorzy:
Menyhárt O; Oncology Biomarker Research Group, Institute of Molecular Life Sciences, Hungarian Research Network, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; Department of Bioinformatics, Semmelweis University, 1094 Budapest, Hungary.
Fekete JT; Oncology Biomarker Research Group, Institute of Molecular Life Sciences, Hungarian Research Network, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; Department of Bioinformatics, Semmelweis University, 1094 Budapest, Hungary.
Győrffy B; Oncology Biomarker Research Group, Institute of Molecular Life Sciences, Hungarian Research Network, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok Körútja 2, 1117 Budapest, Hungary.; Department of Bioinformatics, Semmelweis University, 1094 Budapest, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 15; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 15.
Typ publikacji:
Journal Article
MeSH Terms:
Anthracyclines*/therapeutic use
Inflammatory Breast Neoplasms*
Bridged-Ring Compounds*
Taxoids*
Humans ; Neoplasm Recurrence, Local/drug therapy ; Neoplasm Recurrence, Local/genetics ; Drug Therapy, Combination ; Antibiotics, Antineoplastic ; Inflammation/genetics ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Molecular assessment of drug-phospholipid interactions consequent to cancer treatment: a study of anthracycline-induced cardiotoxicity.
Autorzy:
Ahmed Y; Nanotechnology Program, The American University in Cairo, AUC Avenue, P.O. Box 74, New Cairo, 11835, Egypt.
Elkhodary KI; Department of Mechanical Engineering, The American University in Cairo, AUC Avenue, P.O. Box 74, New Cairo, 11835, Egypt.
Youssef M; Department of Mechanical Engineering, The American University in Cairo, AUC Avenue, P.O. Box 74, New Cairo, 11835, Egypt. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 13; Vol. 13 (1), pp. 22155. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Anthracyclines*/adverse effects
Neoplasms*/drug therapy
Humans ; Cardiotoxicity/etiology ; Phospholipids ; Antibiotics, Antineoplastic/therapeutic use ; Doxorubicin
Czasopismo naukowe
Tytuł:
The effect of a helmet type, home-use low-level light therapy device for chemotherapy-induced alopecia: study protocol for a randomized controlled trial.
Autorzy:
Wu CX; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan.
Li CH; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan.
Shiao YH; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan.; Graduate Institute of Natural Products, Chang Gung University, Taoyuan, 333323, Taiwan.
Cheng HY; The Institute of Health Policy and Management, National Taiwan University, Taipei, 106319, Taiwan.
Wu TH; Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, 20401, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, 33320, Taiwan.
Lee CH; Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan.
Chang ZY; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan.; Institute of Traditional Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan.
Yeh YC; Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, 204201, Taiwan. .; Program in Molecular Medicine, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, 112304, Taiwan. .
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Źródło:
Trials [Trials] 2023 Dec 05; Vol. 24 (1), pp. 789. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Low-Level Light Therapy*
Breast Neoplasms*/drug therapy
Humans ; Female ; Quality of Life ; Head Protective Devices ; Alopecia/chemically induced ; Alopecia/prevention & control ; Alopecia/drug therapy ; Scalp ; Antibiotics, Antineoplastic/adverse effects ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
Utilization of cardiac tests in anthracycline-treated cancer survivors differs between young adults and children: A claims-based analysis.
Autorzy:
Ji X; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Hu X; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Lipscomb J; Department of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Chow EJ; University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Mertens AC; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Castellino SM; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.; Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
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Źródło:
Cancer medicine [Cancer Med] 2023 Dec; Vol. 12 (24), pp. 22056-22061. Date of Electronic Publication: 2023 Dec 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Cancer Survivors*
Neoplasms*/drug therapy
Heart Failure*
Child ; Adolescent ; Humans ; Young Adult ; Anthracyclines/adverse effects ; Antibiotics, Antineoplastic/therapeutic use
Czasopismo naukowe
Tytuł:
Evaluation of cardiotoxicity of anthracycline-containing chemotherapy regimens in patients with bone and soft tissue sarcomas: A study of the FDA adverse event reporting system joint single-center real-world experience.
Autorzy:
Mo Z; Division of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Deng Y; Division of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Bao Y; Department of Oncology, The People's Hospital of Qiannan, Duyun, Guizhou, China.
Liu J; Division of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Jiang Y; Division of Medical Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
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Źródło:
Cancer medicine [Cancer Med] 2023 Dec; Vol. 12 (24), pp. 21709-21724. Date of Electronic Publication: 2023 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Heart Diseases*/chemically induced
Heart Diseases*/diagnosis
Heart Diseases*/epidemiology
Heart Failure*
Sarcoma*/drug therapy
Soft Tissue Neoplasms*/drug therapy
Humans ; Anthracyclines/therapeutic use ; Cardiotoxicity/etiology ; Retrospective Studies ; Stroke Volume ; Ventricular Function, Left ; Antibiotics, Antineoplastic/adverse effects ; Doxorubicin/therapeutic use ; Epirubicin
Czasopismo naukowe
Tytuł:
In vitro comparative study of multimodal imaging nano-assembled microspheres with two clinical drug-eluting beads loaded with doxorubicin.
Autorzy:
He Y; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.; Second Clinical Medical College of Zhejiang, Chinese Medical University, Hangzhou, China.
Xu T; School of Automation, Hangzhou Dianzi University, Hangzhou, China.
Ding T; School of Automation, Hangzhou Dianzi University, Hangzhou, China.
Gong Y; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Zeng H; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Xi Z; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Ye Y; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.; Second Clinical Medical College of Zhejiang, Chinese Medical University, Hangzhou, China.
Song Z; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.; Second Clinical Medical College of Zhejiang, Chinese Medical University, Hangzhou, China.
Pan T; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Zhang Z; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Ma Q; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Li L; School of Automation, Hangzhou Dianzi University, Hangzhou, China.
Zhang Y; School of Automation, Hangzhou Dianzi University, Hangzhou, China.
Shao G; Zhejiang Cancer Hospital, Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.; Second Clinical Medical College of Zhejiang, Chinese Medical University, Hangzhou, China.
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Źródło:
Drug delivery [Drug Deliv] 2023 Dec; Vol. 30 (1), pp. 2197177.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Liver Neoplasms*/drug therapy
Chemoembolization, Therapeutic*/methods
Humans ; Antibiotics, Antineoplastic ; Microspheres ; Doxorubicin
Czasopismo naukowe
Tytuł:
Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice.
Autorzy:
Bosman M; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium.
Krüger DN; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium.
Favere K; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium.; Research Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, Antwerp University Hospital (UZA), Edegem, Belgium.
De Meyer GRY; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium.
Franssen C; Research Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, Antwerp University Hospital (UZA), Edegem, Belgium.
Van Craenenbroeck EM; Research Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.; Department of Cardiology, Antwerp University Hospital (UZA), Edegem, Belgium.
Guns PJ; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium.
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Źródło:
PloS one [PLoS One] 2023 Nov 28; Vol. 18 (11), pp. e0294848. Date of Electronic Publication: 2023 Nov 28 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Dexrazoxane*/pharmacology
Dexrazoxane*/metabolism
Mice ; Animals ; Male ; Reactive Oxygen Species/metabolism ; Cardiotoxicity/drug therapy ; Cardiotoxicity/prevention & control ; Cardiotoxicity/metabolism ; Acetylcholine/metabolism ; Doxorubicin/toxicity ; Doxorubicin/metabolism ; Mice, Inbred C57BL ; Myocytes, Cardiac/metabolism ; Antibiotics, Antineoplastic/pharmacology
Czasopismo naukowe
Tytuł:
A CircRNA-miRNA-mRNA Network for Exploring Doxorubicin- and Myocet-Induced Cardiotoxicity in a Translational Porcine Model.
Autorzy:
Mester-Tonczar J; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Einzinger P; Research Unit of Information and Software, Institute of Information Systems Engineering, 1040 Vienna, Austria.
Hasimbegovic E; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Kastner N; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Schweiger V; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Spannbauer A; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Han E; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Müller-Zlabinger K; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Traxler-Weidenauer D; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Bergler-Klein J; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Gyöngyösi M; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
Lukovic D; Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło:
Biomolecules [Biomolecules] 2023 Nov 27; Vol. 13 (12). Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Swine ; Animals ; RNA, Circular/genetics ; RNA, Messenger/genetics ; Doxorubicin/toxicity ; Cardiotoxicity/genetics ; Antibiotics, Antineoplastic/toxicity ; Sus scrofa/genetics ; Sus scrofa/metabolism
Czasopismo naukowe
Tytuł:
Early skeletal muscle loss in adolescent and young adult cancer patients treated with anthracycline chemotherapy.
Autorzy:
Wooten SV; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Wang F; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Roth ME; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Liu G; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Livingston JA; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.; Department of Sarcoma Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Amini B; Department of Musculoskeletal Imaging, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Gilchrist SC; Department of Cardiology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Hildebrandt M; Department of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Kleinerman ES; Department of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
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Źródło:
Cancer medicine [Cancer Med] 2023 Nov; Vol. 12 (22), pp. 20798-20809. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hodgkin Disease*/chemically induced
Sarcoma*/metabolism
Humans ; Adolescent ; Young Adult ; Mice ; Animals ; Anthracyclines/adverse effects ; Muscle, Skeletal/diagnostic imaging ; Muscle, Skeletal/metabolism ; Antibiotics, Antineoplastic/adverse effects ; Doxorubicin
Czasopismo naukowe
Tytuł:
Radiotherapy-induced enrichment of EGF-modified doxorubicin nanoparticles enhances the therapeutic outcome of lung cancer.
Autorzy:
Wang J; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Zhang Y; Department of Oncology, The Affiliated TCM Hospital of Southwest Medical University, Luzhou, China.
Zhang G; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Xiang L; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Pang H; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Xiong K; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Lu Y; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Li J; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Dai J; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Lin S; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Fu S; Department of Oncology, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 588-599.
Typ publikacji:
Journal Article
MeSH Terms:
Antibiotics, Antineoplastic/*pharmacology
Carcinoma, Non-Small-Cell Lung/*pathology
Doxorubicin/*pharmacology
Epidermal Growth Factor/*metabolism
Lung Neoplasms/*pathology
Nanoparticles/*chemistry
Animals ; Antibiotics, Antineoplastic/administration & dosage ; Apoptosis/drug effects ; Biomimetics ; Cell Proliferation/drug effects ; Chemistry, Pharmaceutical ; Chemoradiotherapy ; Doxorubicin/administration & dosage ; Drug Carriers/chemistry ; Drug Liberation ; ErbB Receptors/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Particle Size ; Surface Properties ; Xenograft Model Antitumor Assays
Czasopismo naukowe

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