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Wyszukujesz frazę ""Antibodies"" wg kryterium: Temat


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Tytuł:
Single-domain antibodies against SARS-CoV-2 RBD from a two-stage phage screening of universal and focused synthetic libraries.
Autorzy:
Chen F; Department of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Liu Z; Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen, China.
Kang W; NanoAI Biotech Co., Ltd, Pingshan District, Shenzhen, China.
Jiang F; NanoAI Biotech Co., Ltd, Pingshan District, Shenzhen, China. .
Yang X; Department of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, China.
Yin F; Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen, China.; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Zhou Z; National Cancer Center, National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Li Z; Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen, China. .; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 13; Vol. 24 (1), pp. 199. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Domain Antibodies*/genetics
Single-Domain Antibodies*/chemistry
Bacteriophages*
COVID-19*/diagnosis
Humans ; SARS-CoV-2/genetics ; Angiotensin-Converting Enzyme 2 ; Antibodies, Viral ; Antibodies, Neutralizing
Czasopismo naukowe
Tytuł:
Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection.
Autorzy:
Frumento N; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sinnis-Bourozikas A; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Paul HT; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Stavrakis G; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Zahid MN; University of Bahrain, Department of Biology, College of Science, Sakhir Campus, Sakhir, Bahrain.
Wang S; Department of Medicine and Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.
Ray SC; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Flyak AI; Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.
Shaw GM; Department of Medicine and Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.
Cox AL; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bailey JR; Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: .
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Źródło:
Immunity [Immunity] 2024 Jan 09; Vol. 57 (1), pp. 40-51.e5. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Neutralizing*
Hepatitis C*
Humans ; Broadly Neutralizing Antibodies ; Hepatitis C Antibodies/chemistry ; Hepacivirus ; Viral Envelope Proteins/genetics
Czasopismo naukowe
Tytuł:
Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Autorzy:
Aksu M; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany.
Kumar P; University Medical Center Göttingen, Dept. of Molecular Oncology, Justus von Liebig Weg 11, 37077 Göttingen, Germany.
Güttler T; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany; Octapharma Biopharmaceuticals GmbH, Im Neuenheimer Feld 590, 69120 Heidelberg, Germany.
Taxer W; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany.
Gregor K; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany.
Mußil B; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany.
Rymarenko O; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany.
Stegmann KM; University Medical Center Göttingen, Dept. of Molecular Oncology, Justus von Liebig Weg 11, 37077 Göttingen, Germany.
Dickmanns A; University Medical Center Göttingen, Dept. of Molecular Oncology, Justus von Liebig Weg 11, 37077 Göttingen, Germany.
Gerber S; University Medical Center Göttingen, Dept. of Molecular Oncology, Justus von Liebig Weg 11, 37077 Göttingen, Germany.
Reineking W; Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Schulz C; Research Center for Emerging Infections and Zoonosis (RIZ), University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Henneck T; Research Center for Emerging Infections and Zoonosis (RIZ), University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany; Department of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Mohamed A; Research Center for Emerging Infections and Zoonosis (RIZ), University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany; Department of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Pohlmann G; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs Str. 1, 30625 Hannover, Germany.
Ramazanoglu M; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs Str. 1, 30625 Hannover, Germany.
Mese K; University Medical Center Göttingen, Dept. of Medical Microbiology and Virology, Kreuzbergring 57, 37075 Göttingen, Germany.
Groß U; University Medical Center Göttingen, Dept. of Medical Microbiology and Virology, Kreuzbergring 57, 37075 Göttingen, Germany.
Ben-Yedidia T; Scinai Immunotherapeutics Ltd., Jerusalem BioPark, Hadassah Ein Kerem, Jerusalem, 9112001, Israel.
Ovadia O; Scinai Immunotherapeutics Ltd., Jerusalem BioPark, Hadassah Ein Kerem, Jerusalem, 9112001, Israel.
Fischer DW; Scinai Immunotherapeutics Ltd., Jerusalem BioPark, Hadassah Ein Kerem, Jerusalem, 9112001, Israel.
Kamensky M; Scinai Immunotherapeutics Ltd., Jerusalem BioPark, Hadassah Ein Kerem, Jerusalem, 9112001, Israel.
Reichman A; Scinai Immunotherapeutics Ltd., Jerusalem BioPark, Hadassah Ein Kerem, Jerusalem, 9112001, Israel.
Baumgärtner W; Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
von Köckritz-Blickwede M; Research Center for Emerging Infections and Zoonosis (RIZ), University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany; Department of Biochemistry, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.
Dobbelstein M; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany; University Medical Center Göttingen, Dept. of Molecular Oncology, Justus von Liebig Weg 11, 37077 Göttingen, Germany. Electronic address: .
Görlich D; Max Planck Institute for Multidisciplinary Sciences, Dept. of Cellular Logistics, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .
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Źródło:
Antiviral research [Antiviral Res] 2024 Jan; Vol. 221, pp. 105778. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Single-Domain Antibodies*
COVID-19*
Animals ; Cricetinae ; Humans ; SARS-CoV-2 ; Respiratory Aerosols and Droplets ; Spike Glycoprotein, Coronavirus ; Cell Culture Techniques ; Antibodies, Neutralizing ; Antibodies, Viral
Czasopismo naukowe
Tytuł:
Microfluidic-assisted single-cell RNA sequencing facilitates the development of neutralizing monoclonal antibodies against SARS-CoV-2.
Autorzy:
Wang Z; School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Huang AS; Dalton Academy, The Affiliated High School of Peking University, Beijing, 100190, China.
Tang L; Dalton Academy, The Affiliated High School of Peking University, Beijing, 100190, China.
Wang J; School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Wang G; Institute for Cell Analysis, Shenzhen Bay Laboratory, Shenzhen, 518132, China. .
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Źródło:
Lab on a chip [Lab Chip] 2024 Feb 13; Vol. 24 (4), pp. 642-657. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Neutralizing*
COVID-19*
Humans ; SARS-CoV-2/genetics ; Neutralization Tests ; Antibodies, Monoclonal/metabolism ; Microfluidics ; Sequence Analysis, RNA ; Antibodies, Viral
Czasopismo naukowe
Tytuł:
A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
Autorzy:
de Campos-Mata L; Translational Clinical Research Program, Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Trinité B; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Modrego A; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Tejedor Vaquero S; Translational Clinical Research Program, Hospital del Mar Research Institute (IMIM), Barcelona, Spain.
Pradenas E; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Pons-Grífols A; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Rodrigo Melero N; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Carlero D; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Marfil S; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Santiago C; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Raïch-Regué D; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Bueno-Carrasco MT; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Tarrés-Freixas F; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.; IRTA. Programa de Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.
Abancó F; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Urrea V; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Izquierdo-Useros N; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.; CIBERINFEC, ISCIII, Madrid, Spain.
Riveira-Muñoz E; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.
Ballana E; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain.; CIBERINFEC, ISCIII, Madrid, Spain.; Germans Trias i Pujol Research Institute (IGTP), Can Ruti Campus, Badalona, Spain.
Pérez M; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; IRTA. Programa de Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.
Vergara-Alert J; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; IRTA. Programa de Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.
Segalés J; Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.
Carolis C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain. .
Arranz R; Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. .
Blanco J; IrsiCaixa AIDS Research Institute, Hospital Germans Trias I Pujol, Campus Can Ruti, Badalona, Spain. .; CIBERINFEC, ISCIII, Madrid, Spain. .; Germans Trias i Pujol Research Institute (IGTP), Can Ruti Campus, Badalona, Spain. .; Infectious Diseases and Immunity, Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Barcelona, Spain. .
Magri G; Translational Clinical Research Program, Hospital del Mar Research Institute (IMIM), Barcelona, Spain. .; Immunology Unit, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain. .
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Źródło:
Nature communications [Nat Commun] 2024 Feb 05; Vol. 15 (1), pp. 1051. Date of Electronic Publication: 2024 Feb 05.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal*
COVID-19*
Humans ; Animals ; Mice ; SARS-CoV-2 ; Cryoelectron Microscopy ; Antibodies, Monoclonal, Humanized ; Antibodies, Neutralizing ; Antibodies, Viral ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
A bispecific antibody targeting HER2 and CLDN18.2 eliminates gastric cancer cells expressing dual antigens by enhancing the immune effector function.
Autorzy:
Yue J; School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, 264003, China.
Shao S; RemeGen Co., Ltd., 58 Middle Beijing Road, Yantai, ShanDong, 264006, China.
Zhou J; RemeGen Co., Ltd., 58 Middle Beijing Road, Yantai, ShanDong, 264006, China.
Luo W; RemeGen Co., Ltd., 58 Middle Beijing Road, Yantai, ShanDong, 264006, China.
Xu Y; RemeGen Co., Ltd., 58 Middle Beijing Road, Yantai, ShanDong, 264006, China.
Zhang Q; RemeGen Co., Ltd., 58 Middle Beijing Road, Yantai, ShanDong, 264006, China.
Jiang J; School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, 264003, China.
Zhu MM; School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, 264003, China. .
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Źródło:
Investigational new drugs [Invest New Drugs] 2024 Feb; Vol. 42 (1), pp. 106-115. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Stomach Neoplasms*/drug therapy
Antibodies, Bispecific*/pharmacology
Antibodies, Bispecific*/therapeutic use
Humans ; Cell Line, Tumor ; Trastuzumab/pharmacology ; Trastuzumab/therapeutic use ; Receptor, ErbB-2/metabolism ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Claudins
Czasopismo naukowe
Tytuł:
Re-Engineering Therapeutic Anti-Aβ Monoclonal Antibody to Target Amyloid Light Chain.
Autorzy:
Bai J; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Li X; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhao J; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, USA.
Zong H; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.; Jecho Biopharmaceutical Institute, Shanghai 200240, China.
Yuan Y; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Wang L; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhang X; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Ke Y; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Han L; Jecho Biopharmaceutical Institute, Shanghai 200240, China.
Xu J; School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.
Ma B; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhang B; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
Zhu J; Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.; Jecho Biopharmaceutical Institute, Shanghai 200240, China.; Jecho Laboratories, Inc., Frederick, MD 21704, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 27; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 27.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Alzheimer Disease*/therapy
Amyloidosis*/therapy
Antibodies, Monoclonal, Humanized*/pharmacology
Antibodies, Monoclonal, Humanized*/therapeutic use
Humans ; Amyloid/metabolism ; Amyloid beta-Peptides/immunology ; Amyloid beta-Peptides/metabolism ; Amyloidogenic Proteins/therapeutic use ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Peptide Fragments/metabolism
Czasopismo naukowe
Tytuł:
SARS-CoV-2 Specific Nanobodies Neutralize Different Variants of Concern and Reduce Virus Load in the Brain of h-ACE2 Transgenic Mice.
Autorzy:
Pavan MF; Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires ZC 1428, Argentina.
Bok M; Incuinta, Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.; Instituto de Virología e Innovaciones Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (IVIT-CONICET), Hurlingham, Buenos Aires ZC 1686, Argentina.
Betanzos San Juan R; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), Departamento de Química Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires ZC 1428, Argentina.
Malito JP; Incuinta, Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.; Instituto de Virología e Innovaciones Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (IVIT-CONICET), Hurlingham, Buenos Aires ZC 1686, Argentina.
Marcoppido GA; Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.
Franco DR; Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.
Militelo DA; Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires ZC 1428, Argentina.
Schammas JM; Instituto de Virología e Innovaciones Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (IVIT-CONICET), Hurlingham, Buenos Aires ZC 1686, Argentina.
Bari SE; Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires ZC 1428, Argentina.
Stone W; Department of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
López K; Department of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Porier DL; Department of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Muller JA; Department of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Auguste AJ; Department of Entomology, College of Agriculture and Life Sciences, Fralin Life Science Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.; Center for Emerging, Zoonotic, and Arthropod-Borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Yuan L; Center for Emerging, Zoonotic, and Arthropod-Borne Pathogens, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Wigdorovitz A; Incuinta, Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.; Instituto de Virología e Innovaciones Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (IVIT-CONICET), Hurlingham, Buenos Aires ZC 1686, Argentina.
Parreño VG; Incuinta, Instituto Nacional de Tecnología Agropecuaria (INTA), Hurlingham, Buenos Aires ZC 1686, Argentina.; Instituto de Virología e Innovaciones Tecnológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (IVIT-CONICET), Hurlingham, Buenos Aires ZC 1686, Argentina.; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Ibañez LI; Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires ZC 1428, Argentina.
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Źródło:
Viruses [Viruses] 2024 Jan 25; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Domain Antibodies*/genetics
COVID-19*
Camelids, New World*
Animals ; Mice ; Humans ; Angiotensin-Converting Enzyme 2/genetics ; SARS-CoV-2/genetics ; Pandemics ; Brain ; Mice, Transgenic ; Spike Glycoprotein, Coronavirus/genetics ; Antibodies, Neutralizing ; Antibodies, Viral
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Nanobodies: a promising approach to treatment of viral diseases.
Autorzy:
Minatel VM; Center for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu, São Paulo, Brazil.
Prudencio CR; Immunology Center, Adolfo Lutz Institute, São Paulo, São Paulo, Brazil.
Barraviera B; Center for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu, São Paulo, Brazil.; Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu, São Paulo, Brazil.
Ferreira RS Jr; Center for the Study of Venoms and Venomous Animals (CEVAP), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu, São Paulo, Brazil.; Graduate Program in Tropical Diseases, Botucatu Medical School (FMB), São Paulo State University (UNESP-Univ Estadual Paulista), Botucatu, São Paulo, Brazil.
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Źródło:
Frontiers in immunology [Front Immunol] 2024 Jan 23; Vol. 14, pp. 1303353. Date of Electronic Publication: 2024 Jan 23 (Print Publication: 2023).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Single-Domain Antibodies*
Virus Diseases*
Humans ; Tissue Distribution ; Antibodies/metabolism ; Epitopes/metabolism
Czasopismo naukowe
Tytuł:
A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Autorzy:
Ballegeer M; VIB Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
van Scherpenzeel RC; Janssen Infectious Diseases and Vaccines, Beerse, Belgium.
Delgado T; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Iglesias-Caballero M; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
García Barreno B; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
Pandey S; VIB Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
Rush SA; Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Kolkman JA; Janssen Infectious Diseases and Vaccines, Beerse, Belgium.
Mas V; Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Saelens X; VIB Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
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Źródło:
MBio [mBio] 2024 Jan 16; Vol. 15 (1), pp. e0212223. Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Metapneumovirus*/genetics
Metapneumovirus*/metabolism
Single-Domain Antibodies*
Humans ; Antibodies, Viral ; Antibodies, Neutralizing ; Epitopes ; Viral Fusion Proteins/metabolism
Czasopismo naukowe
Tytuł:
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability.
Autorzy:
Gorman J; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Cheung CS; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Duan Z; NCI Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Ou L; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Wang M; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Chen X; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Cheng C; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Biju A; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Sun Y; NCI Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Wang P; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA.
Yang Y; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Zhang B; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Boyington JC; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Bylund T; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Charaf S; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Chen SJ; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Du H; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Henry AR; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Liu T; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Sarfo EK; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Schramm CA; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Shen CH; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Stephens T; Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Teng IT; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Todd JP; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Tsybovsky Y; Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.
Verardi R; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Wang D; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Wang S; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Wang Z; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Zheng CY; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Zhou T; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Douek DC; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Mascola JR; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA.
Ho DD; Aaron Diamond AIDS Research Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 10032, USA. .
Ho M; NCI Antibody Engineering Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. .
Kwong PD; Vaccine Research Center, National Institutes of Health, Bethesda, MD, 20892, USA. .
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Źródło:
Nature communications [Nat Commun] 2024 Jan 04; Vol. 15 (1), pp. 285. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Domain Antibodies*
Lassa Fever*
Animals ; Guinea Pigs ; Lassa virus ; Antibodies, Viral ; Antibodies, Neutralizing
Czasopismo naukowe
Tytuł:
Utilizing targeted integration CHO pools to potentially accelerate the GMP manufacturing of monoclonal and bispecific antibodies.
Autorzy:
Barnard GC; Cell Culture and Bioprocess Operations, Genentech, South San Francisco, California, USA.
Zhou M; Cell Culture and Bioprocess Operations, Genentech, South San Francisco, California, USA.
Shen A; Cell Culture and Bioprocess Operations, Genentech, South San Francisco, California, USA.
Yuk IH; Cell Culture and Bioprocess Operations, Genentech, South San Francisco, California, USA.
Laird MW; Cell Culture and Bioprocess Operations, Genentech, South San Francisco, California, USA.
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Źródło:
Biotechnology progress [Biotechnol Prog] 2024 Jan-Feb; Vol. 40 (1), pp. e3399. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bispecific*/genetics
Cricetinae ; Animals ; Cricetulus ; CHO Cells ; Antibodies, Monoclonal/genetics ; Clone Cells
Czasopismo naukowe
Tytuł:
Immunogenicity of Cemiplimab: Low Incidence of Antidrug Antibodies and Cut-Point Suitability Across Tumor Types.
Autorzy:
Valentine JL; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Dengler A; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Zhao A; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Truong T; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
McAfee S; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Hassanein M; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Irvin SC; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Chen J; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Meng X; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Yan H; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Torri A; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Sumner G; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Andisik MD; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Paccaly A; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Partridge MA; Bioanalytical Sciences and Pharmacometrics, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
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Źródło:
Journal of clinical pharmacology [J Clin Pharmacol] 2024 Jan; Vol. 64 (1), pp. 125-136. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Monoclonal, Humanized*/therapeutic use
Neoplasms*/drug therapy
Humans ; Incidence ; Antibodies, Monoclonal/therapeutic use
Czasopismo naukowe
Tytuł:
Generation of Endotoxin-Specific Monoclonal Antibodies by Phage and Yeast Display for Capturing Endotoxin.
Autorzy:
Fux AC; Department of Biosciences and Medical Biology, Paris Lodron University of Salzburg, 5020 Salzburg, Austria.; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Casonato Melo C; Department of Biosciences and Medical Biology, Paris Lodron University of Salzburg, 5020 Salzburg, Austria.; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Schlahsa L; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Burzan NB; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Felsberger A; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Gessner I; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Fauerbach JA; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Horejs-Hoeck J; Department of Biosciences and Medical Biology, Paris Lodron University of Salzburg, 5020 Salzburg, Austria.
Droste M; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
Siewert C; Research and Development Department, Miltenyi Biotec B.V. & Co. KG, 51429 Bergisch Gladbach, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Bacteriophages*/genetics
Single-Chain Antibodies*
Humans ; Antibodies, Monoclonal ; Saccharomyces cerevisiae/metabolism ; Peptide Library ; Endotoxins ; Lipopolysaccharides
Czasopismo naukowe
Tytuł:
Neutralizing antibody levels detected early after mRNA-based vaccination do not predict by themselves subsequent breakthrough infections of SARS-CoV-2.
Autorzy:
Alonso R; Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; CIBER (Centro de Investigación Biomédicas en Red) de Enfermedades Respiratorias, CIBERES, Barcelona, Spain.; Department of Medicine, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
Gil-Manso S; Advanced ImmunoRegulation Group, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Catalán P; Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; CIBER (Centro de Investigación Biomédicas en Red) de Enfermedades Respiratorias, CIBERES, Barcelona, Spain.
Sánchez-Arcilla I; Department of Labour Risks Prevention, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Marzola M; Department of Labour Risks Prevention, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Correa-Rocha R; Laboratory of Immune-Regulation, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Muñoz P; Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.; CIBER (Centro de Investigación Biomédicas en Red) de Enfermedades Respiratorias, CIBERES, Barcelona, Spain.; Department of Medicine, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
Pion M; Advanced ImmunoRegulation Group, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
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Corporate Authors:
Gregorio Marañón Microbiology-ID COVID-19 Study Group
Źródło:
Frontiers in immunology [Front Immunol] 2024 Feb 09; Vol. 15, pp. 1341313. Date of Electronic Publication: 2024 Feb 09 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Neutralizing*
COVID-19*/prevention & control
Humans ; SARS-CoV-2 ; BNT162 Vaccine ; Breakthrough Infections ; Antibodies, Viral ; RNA, Messenger ; Vaccination ; Immunoglobulin G
Czasopismo naukowe
Tytuł:
Anti-Idiotypic Nanobodies Mimicking an Epitope of the Needle Protein of the Chlamydial Type III Secretion System for Targeted Immune Stimulation.
Autorzy:
Koroleva EA; Institute of Gene Biology of the Russian Academy of Sciences, Vavilova Str. 34/5, 119334 Moscow, Russia.; National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
Goryainova OS; Institute of Gene Biology of the Russian Academy of Sciences, Vavilova Str. 34/5, 119334 Moscow, Russia.; Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Vavilova Str. 32, 119991 Moscow, Russia.
Ivanova TI; Institute of Gene Biology of the Russian Academy of Sciences, Vavilova Str. 34/5, 119334 Moscow, Russia.
Rutovskaya MV; Institute of Gene Biology of the Russian Academy of Sciences, Vavilova Str. 34/5, 119334 Moscow, Russia.
Zigangirova NA; National Research Center for Epidemiology and Microbiology Named after the Honorary Academician N. F. Gamaleya, 123098 Moscow, Russia.
Tillib SV; Institute of Gene Biology of the Russian Academy of Sciences, Vavilova Str. 34/5, 119334 Moscow, Russia.; Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Vavilova Str. 32, 119991 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Domain Antibodies*
Chlamydia Infections*
Humans ; Mice ; Animals ; Female ; Epitopes ; Type III Secretion Systems ; Chlamydia trachomatis ; Antibodies, Bacterial
Czasopismo naukowe
Tytuł:
Distinct roles of vaccine-induced SARS-CoV-2-specific neutralizing antibodies and T cells in protection and disease.
Autorzy:
Yan J; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Bangalore CR; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Nikouyan N; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
Appelberg S; Public Health Agency of Sweden, Stockholm, Sweden.
Silva DN; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Yao H; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Pasetto A; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Weber F; Institute for Virology, FB10-Veterinary Medicine, Justus-Liebig University Giessen, Giessen, Germany.
Weber S; Adlego AB, Uppsala, Sweden.
Larsson O; Adlego AB, Uppsala, Sweden.
Höglund U; Adlego AB, Uppsala, Sweden.
Bogdanovic G; Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
Grabbe M; Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
Aleman S; Infectious Disease Clinic, Karolinska University Hospital, Stockholm, Sweden.
Szekely L; Department of Pathology, Karolinska University Hospital, Stockholm, Sweden.
Szakos A; Department of Pathology, Karolinska University Hospital, Stockholm, Sweden.
Tuvesson O; Northx Biologics, Matfors, Sweden.
Gidlund EK; Northx Biologics, Matfors, Sweden.
Cadossi M; IGEA Spa, Carpi, Italy.
Salati S; IGEA Spa, Carpi, Italy.
Tegel H; Department of Protein Science, KTH - Royal Institute of Technology, 10691 Stockholm, Sweden.
Hober S; Department of Protein Science, KTH - Royal Institute of Technology, 10691 Stockholm, Sweden.
Frelin L; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Mirazimi A; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Public Health Agency of Sweden, Stockholm, Sweden.
Ahlén G; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden.
Sällberg M; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Karolinska ATMP Center, Stockholm, Sweden. Electronic address: .
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Źródło:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Feb 07; Vol. 32 (2), pp. 540-555. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Neutralizing*
COVID-19*/prevention & control
COVID-19 Vaccines*/adverse effects
Animals ; Humans ; Mice ; Antibodies, Viral ; CD8-Positive T-Lymphocytes ; SARS-CoV-2 ; Viral Vaccines
Czasopismo naukowe
Tytuł:
Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism.
Autorzy:
Nunn E; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Jaiswal N; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Gavin M; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Uehara K; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Stefkovich M; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Drareni K; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Calhoun R; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Lee M; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Holman CD; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Baur JA; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Seale P; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Titchenell PM; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło:
Molecular metabolism [Mol Metab] 2024 Feb; Vol. 80, pp. 101880. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Activin Receptors, Type II*/antagonists & inhibitors
Activin Receptors, Type II*/metabolism
Glucagon-Like Peptide-1 Receptor*/agonists
Glucagon-Like Peptide-1 Receptor*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Weight Loss*
Antibodies, Monoclonal, Humanized*/administration & dosage
Obesity*/drug therapy
Animals ; Mice ; Activins/metabolism ; Antibodies, Blocking/metabolism ; Antibodies, Blocking/pharmacology ; Antibodies, Blocking/therapeutic use ; Hypertrophy/metabolism ; Mice, Obese ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Tytuł:
Combination treatment with monoclonal antibodies: Dupilumab and ustekinumab for the treatment of severe atopic dermatitis and Crohn disease.
Autorzy:
Alegre-Bailo A; Dermatology Department of the Rey Juan Carlos Hospital, Móstoles, Madrid, Spain.
Sánchez-Gilo A; Dermatology Department of the Rey Juan Carlos Hospital, Móstoles, Madrid, Spain.
Gonzalo González I; Dermatology Department of the Infanta Elena Hospital, Valdemoro, Madrid, Spain.
Vicente Martín FJ; Dermatology Department of the Rey Juan Carlos Hospital, Móstoles, Madrid, Spain.
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Źródło:
The Australasian journal of dermatology [Australas J Dermatol] 2024 Feb; Vol. 65 (1), pp. 63-66. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Dermatitis, Atopic*/drug therapy
Crohn Disease*/drug therapy
Antibodies, Monoclonal, Humanized*
Humans ; Antibodies, Monoclonal/therapeutic use ; Ustekinumab/therapeutic use ; Treatment Outcome ; Severity of Illness Index
Czasopismo naukowe
Tytuł:
Placental Transfer Efficiency of Neutralizing Antibodies on SARS-CoV-2 Vaccination before and after Pregnancy in Mexican Women.
Autorzy:
Martínez-Quezada R; Unidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla Km. 34.5, Pueblo de Zoquiapan, Ixtapaluca 56530, Mexico.; Consejo Mexiquense de Ciencia y Tecnología (COMECYT), Paseo Colón N° 112-A, Ciprés, Toluca 50120, Mexico.
Miguel-Rodríguez CE; Unidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla Km. 34.5, Pueblo de Zoquiapan, Ixtapaluca 56530, Mexico.
Ramírez-Lozada T; Unidad de Ginecología y Obstetricia, Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla Km. 34.5, Pueblo de Zoquiapan, Ixtapaluca 56530, Mexico.
Valencia-Ledezma OE; Unidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla Km. 34.5, Pueblo de Zoquiapan, Ixtapaluca 56530, Mexico.
Acosta-Altamirano G; Unidad de Investigación, Hospital Regional de Alta Especialidad de Ixtapaluca, Carretera Federal México-Puebla Km. 34.5, Pueblo de Zoquiapan, Ixtapaluca 56530, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Neutralizing*
COVID-19*/prevention & control
Infant, Newborn ; Pregnancy ; Female ; Humans ; COVID-19 Vaccines ; SARS-CoV-2 ; Placenta ; Vaccination ; Mothers ; Antibodies, Viral
Czasopismo naukowe

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