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Wyświetlanie 21-40 z 282268
Tytuł:
Pediatric ANCA vasculitis: clinical presentation, treatment, and outcomes in a French retrospective study.
Autorzy:
Mahi SL; Service de Pédiatrie 1, CHU University Hospital Hautepierre, 1, Avenue Molière, 67098, Strasbourg, France.
Bahram S; Laboratoire d'Immunologie (HUS), ImmunoRhumatologie Moléculaire (INSERM UMR_S1109), CHU Strasbourg, Strasbourg, France.
Harambat J; Service de Néphrologie Pédiatrique, Centre de Référence Maladies Rénales Rares du Sud-Ouest, CHU de Bordeux, Bordeaux, France.
Allard L; Service de Néphrologie Pédiatrique, Centre de Référence Maladies Rénales Rares du Sud-Ouest, CHU de Bordeux, Bordeaux, France.
Merlin E; Service de Pédiatrie Générale Multidisciplinaire, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Belot A; Service de Néphrologie-Rhumatologie-Dermatologie Pédiatriques, Hospices Civils de Lyon, Lyon, France.
Ranchin B; Service de Néphrologie-Rhumatologie-Dermatologie Pédiatriques, Hospices Civils de Lyon, Lyon, France.
Tenenbaum J; Service de Pédiatrie, CHU Arnaud de Villeneuve, Montpellier, France.
Magnavacca M; Service de Pédiatrie, CHRU Nancy, Nancy, France.
Haumesser L; Departement Statistiques, CHU Strasbourg, Strasbourg, France.
Allain-Launay E; Service de Pédiatrie, CHU Nantes, Nantes, France.
Pietrement C; Servie de Pédiatrie Spécialisée Et Généralisée, CHU Reims, Reims, France.
Flodrops H; Service de Néphrologie Pédiatrique, CHU La Réunion, La Réunion, France.
Ruin M; Service de Néphrologie Pédiatrique, CHU La Réunion, La Réunion, France.
Dossier C; Service de Néphrologie Pédiatrique, CHU Robert Debré, Paris, France.
Decramer S; Service de pédiatrie - néphrologie et médecine interne, CHU Toulouse, Toulouse, France.
Ballot-Schmitt C; Service de Médecine Pédiatrique, CHU Besançon, Besançon, France.
Boyer OG; Service de Néphrologie Pédiatrique, Hôpital Necker Enfants Malades AP-HP, Paris, France.
Seugé L; Service de Néphrologie Pédiatrique, Hôpital Necker Enfants Malades AP-HP, Paris, France.
Ulinski T; Service de Néphrologie Pédiatrique, CHU Trousseau, Paris, France.
Zaloszyc A; Service de Pédiatrie 1, CHU University Hospital Hautepierre, 1, Avenue Molière, 67098, Strasbourg, France. .; Laboratoire d'Immunologie (HUS), ImmunoRhumatologie Moléculaire (INSERM UMR_S1109), CHU Strasbourg, Strasbourg, France. .
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Źródło:
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2023 Aug; Vol. 38 (8), pp. 2649-2658. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Antineutrophil Cytoplasmic*
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/diagnosis
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/drug therapy
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/epidemiology
Adult ; Humans ; Child ; Retrospective Studies ; Rituximab/therapeutic use ; Prospective Studies ; Recurrence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Autoantibody Profiling and Anti-Kinesin Reactivity in ANCA-Associated Vasculitis.
Autorzy:
Mescia F; Department of Medicine, University of Cambridge, Cambridge CB2 0SP, UK.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge CB2 0AW, UK.; Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.
Bayati S; Department of Protein Science, KTH Royal Institute of Technology, SciLifeLab, 171 65 Stockholm, Sweden.
Brouwer E; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Heeringa P; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Toonen EJM; R&D Department, Hycult Biotech, 5405 PB Uden, The Netherlands.
Beenes M; R&D Department, Hycult Biotech, 5405 PB Uden, The Netherlands.
Ball MJ; Department of Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Rees AJ; Department of Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Kain R; Department of Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Lyons PA; Department of Medicine, University of Cambridge, Cambridge CB2 0SP, UK.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, Cambridge CB2 0AW, UK.
Nilsson P; Department of Protein Science, KTH Royal Institute of Technology, SciLifeLab, 171 65 Stockholm, Sweden.
Pin E; Department of Protein Science, KTH Royal Institute of Technology, SciLifeLab, 171 65 Stockholm, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 19; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Autoantibodies*
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/diagnosis
Humans ; Kinesins ; Biomarkers ; Proteins/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chemokines and Cytokines Profiles in Patients with Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis: A Preliminary Study.
Autorzy:
Daca A; Department of Pathophysiology, Medical University of Gdańsk, 80-211 Gdansk, Poland.
Storoniak H; Department of Nephrology, Transplantology, and Internal Diseases, Medical University of Gdańsk, 80-211 Gdansk, Poland.
Dębska-Ślizień A; Department of Nephrology, Transplantology, and Internal Diseases, Medical University of Gdańsk, 80-211 Gdansk, Poland.
Kusztal MA; Department of Nephrology and Translational Medicine, Medical University of Wrocław, 50-137 Wroclaw, Poland.
Krajewska M; Department of Nephrology and Translational Medicine, Medical University of Wrocław, 50-137 Wroclaw, Poland.
Lisowska KA; Department of Pathophysiology, Medical University of Gdańsk, 80-211 Gdansk, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 18; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*
Kidney Diseases*
Humans ; Antibodies, Antineutrophil Cytoplasmic ; Interleukin-10 ; Interleukin-6 ; Interleukin-8 ; Chemokine CXCL10 ; Cytokines ; Interferon-alpha/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform.
Autorzy:
Nguyen NTB; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Leung HW; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Pang KT; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Tay SJ; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Walsh I; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Choo ABH; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Yang Y; Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore. yang_.
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 20; Vol. 13 (1), pp. 15620. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal*/genetics
Antibody-Dependent Cell Cytotoxicity*
Animals ; Cricetinae ; Cricetulus ; Apoptosis ; Polysaccharides/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced antibody-antigen structure prediction from molecular docking using AlphaFold2.
Autorzy:
Gaudreault F; Human Health Therapeutics Research Centre, National Research Council Canada, 6100 Royalmount Avenue, Montreal, QC, H4P 2R2, Canada.
Corbeil CR; Human Health Therapeutics Research Centre, National Research Council Canada, 6100 Royalmount Avenue, Montreal, QC, H4P 2R2, Canada.
Sulea T; Human Health Therapeutics Research Centre, National Research Council Canada, 6100 Royalmount Avenue, Montreal, QC, H4P 2R2, Canada. .; Institute of Parasitology, McGill University, 21111 Lakeshore Road, Sainte-Anne-de-Bellevue, QC, H9X 3V9, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 13; Vol. 13 (1), pp. 15107. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Furylfuramide*
Antigen-Antibody Complex*
Molecular Docking Simulation ; Benchmarking ; Biological Evolution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Renal histopathological predictors of end-stage kidney disease in ANCA-associated vasculitis with glomerulonephritis: a single-centre study in Korea.
Autorzy:
Choi SE; Department of Pathology, CHA University, CHA Bundang Medical Center, Seongnam-si, Kyeonggi-do, Republic of Korea.
Lee SB; Department of Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Pyo JY; Division of Rheumatology Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Ahn SS; Division of Rheumatology Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Song JJ; Division of Rheumatology Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea.
Park YB; Division of Rheumatology Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea.
Lim BJ; Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Republic of Korea. .
Lee SW; Division of Rheumatology Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. .; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 08; Vol. 13 (1), pp. 14850. Date of Electronic Publication: 2023 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Kidney Failure, Chronic*/etiology
Glomerulonephritis*/complications
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/complications
Male ; Humans ; Middle Aged ; Female ; Kidney ; Republic of Korea/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antibody production and characterization of the nucleoprotein of sever fever with thrombocytopenia syndrome virus (SFTSV) for effective diagnosis of SFTSV.
Autorzy:
Lee K; Graduate School of Biotechnology, Kyung Hee University, Yongin, 17104, Korea.
Choi MJ; Department of Genetics and Biotechnology, Kyung Hee University, Yongin, 17104, Korea.
Cho MH; Department of Genetics and Biotechnology, Kyung Hee University, Yongin, 17104, Korea.
Choi DO; Bore Da Biotech, Seongnam-si, Gyeonggi-do, 13209, Korea.
Bhoo SH; Graduate School of Green-Bio Science, Kyung Hee University, Yongin, 17104, Korea. .
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Źródło:
Virology journal [Virol J] 2023 Sep 07; Vol. 20 (1), pp. 206. Date of Electronic Publication: 2023 Sep 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibody Formation*
Thrombocytopenia*
Animals ; Mice ; Nucleoproteins/genetics ; Escherichia coli ; Fever ; Antibodies, Monoclonal ; Epitopes
SCR Organism:
SFTS phlebovirus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The emergence of SARS-CoV-2 lineages and associated saliva antibody responses among asymptomatic individuals in a large university community.
Autorzy:
Merling MR; Department of Microbial Infection & Immunity, The Ohio State University, Columbus, Ohio, United States of America.
Williams A; Department of Microbial Infection & Immunity, The Ohio State University, Columbus, Ohio, United States of America.; Infectious Disease Institute, The Ohio State University, Columbus, Ohio, United States of America.
Mahfooz NS; Department of Microbial Infection & Immunity, The Ohio State University, Columbus, Ohio, United States of America.
Ruane-Foster M; Department of Microbial Infection & Immunity, The Ohio State University, Columbus, Ohio, United States of America.
Smith J; Infectious Disease Institute, The Ohio State University, Columbus, Ohio, United States of America.
Jahnes J; Infectious Disease Institute, The Ohio State University, Columbus, Ohio, United States of America.
Ayers LW; Department of Pathology, The Ohio State University, Columbus, Ohio, United States of America.
Bazan JA; Division of Infectious Disease, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Norris A; Division of Infectious Disease, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.; Department of Epidemiology, The Ohio State University, Columbus, Ohio, United States of America.
Norris Turner A; Division of Infectious Disease, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.
Oglesbee M; Infectious Disease Institute, The Ohio State University, Columbus, Ohio, United States of America.
Faith SA; Infectious Disease Institute, The Ohio State University, Columbus, Ohio, United States of America.
Quam MB; Department of Epidemiology, The Ohio State University, Columbus, Ohio, United States of America.
Robinson RT; Department of Microbial Infection & Immunity, The Ohio State University, Columbus, Ohio, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Aug 21; Vol. 19 (8), pp. e1011596. Date of Electronic Publication: 2023 Aug 21 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibody Formation*
COVID-19*/epidemiology
Aged ; Humans ; SARS-CoV-2 ; Saliva ; Universities ; Breakthrough Infections ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BA.1/BA.5 Immunogenicity, Reactogenicity, and Disease Activity after COVID-19 Vaccination in Patients with ANCA-Associated Vasculitis: A Prospective Observational Cohort Study.
Autorzy:
Speer C; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.; Molecular Medicine Partnership Unit Heidelberg, EMBL, 69120 Heidelberg, Germany.
Töllner M; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Benning L; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Bartenschlager M; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Medical Faculty Heidelberg, Heidelberg University, 68167 Heidelberg, Germany.
Kim H; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Medical Faculty Heidelberg, Heidelberg University, 68167 Heidelberg, Germany.
Nusshag C; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Kälble F; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Reineke M; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Reichel P; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Schnitzler P; Department of Infectious Diseases, Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Zeier M; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Morath C; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Schmitt W; Center for Renal Diseases, 69469 Weinheim, Germany.
Bergner R; Department of Internal Medicine A, Clinical Center Ludwigshafen, 67071 Ludwigshafen, Germany.
Bartenschlager R; Department of Infectious Diseases, Molecular Virology, Center for Integrative Infectious Disease Research, Medical Faculty Heidelberg, Heidelberg University, 68167 Heidelberg, Germany.; German Center for Infection Research (DZIF), Heidelberg Partner Site, 69120 Heidelberg, Germany.; Division Virus-Associated Carcinogenesis, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Lorenz HM; Division of Rheumatology, Department of Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
Schaier M; Department of Nephrology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
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Źródło:
Viruses [Viruses] 2023 Aug 21; Vol. 15 (8). Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/prevention & control
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*
Humans ; COVID-19 Vaccines/adverse effects ; Prospective Studies ; SARS-CoV-2 ; Vaccination ; Antibodies, Neutralizing ; mRNA Vaccines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Attenuating nicotine's effects with high affinity human anti-nicotine monoclonal antibodies.
Autorzy:
Raleigh MD; Hennepin Healthcare Research Institute, Minneapolis, Minnesota, United States of America.; Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota, United States of America.
Beltraminelli N; Blink Biomedical, Marseille, France.
Fallot S; Blink Biomedical, Marseille, France.
LeSage MG; Hennepin Healthcare Research Institute, Minneapolis, Minnesota, United States of America.; Nic•mAb Strategic Alliance, San Diego, California, United States of America.
Saykao A; Hennepin Healthcare Research Institute, Minneapolis, Minnesota, United States of America.
Pentel PR; Hennepin Healthcare Research Institute, Minneapolis, Minnesota, United States of America.; Nic•mAb Strategic Alliance, San Diego, California, United States of America.
Fuller S; Nic•mAb Strategic Alliance, San Diego, California, United States of America.; Antidote Therapeutics, Inc., Woodbine, Maryland, United States of America.
Thisted T; Nic•mAb Strategic Alliance, San Diego, California, United States of America.; Antidote Therapeutics, Inc., Woodbine, Maryland, United States of America.
Biesova Z; Antidote Therapeutics, Inc., Woodbine, Maryland, United States of America.
Horrigan S; Noble Life Sciences, Woodbine, Maryland, United States of America.
Sampey D; Nic•mAb Strategic Alliance, San Diego, California, United States of America.; Biofactura, Inc., Frederick, Maryland, United States of America.
Zhou B; Nic•mAb Strategic Alliance, San Diego, California, United States of America.; The Scripps Research Institute, La Jolla, California, United States of America.
Kalnik MW; Nic•mAb Strategic Alliance, San Diego, California, United States of America.; Antidote Therapeutics, Inc., Woodbine, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jul 30; Vol. 16 (7), pp. e0254247. Date of Electronic Publication: 2021 Jul 30 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antibodies, Monoclonal*/chemistry
Antibodies, Monoclonal*/pharmacokinetics
Antibodies, Monoclonal*/pharmacology
Antibody Affinity*
Nicotine*/chemistry
Nicotine*/pharmacokinetics
Tobacco Use Disorder*/drug therapy
Tobacco Use Disorder*/metabolism
Brain/*metabolism
Animals ; Antigen-Antibody Complex/chemistry ; Humans ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mobility and disorder in antibody and antigen binding sites do not prevent immunochemical recognition.
Autorzy:
Uversky VN; Department of Molecular Medicine, USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.; Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, Russia.
Van Regenmortel MHV; Ecole Superieure de Biotechnologie de Strasbourg, CNRS Research Unit UMR 7242, Illkirch, France.
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Źródło:
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2021 Apr; Vol. 56 (2), pp. 149-156. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antigen-Antibody Reactions*
Antibodies/*immunology
Antigens/*immunology
Epitopes/*immunology
Animals ; Antibodies/chemistry ; Antigens/chemistry ; Binding Sites, Antibody ; Epitopes/chemistry ; Humans ; Intrinsically Disordered Proteins/chemistry ; Intrinsically Disordered Proteins/immunology ; Protein Conformation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
NanoBERTa-ASP: predicting nanobody paratope based on a pretrained RoBERTa model.
Autorzy:
Li S; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China.
Meng X; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China.
Li R; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China.
Huang B; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China. .
Wang X; College of Big Data and Internet, Shenzhen Technology University, Shenzhen, China. .
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Źródło:
BMC bioinformatics [BMC Bioinformatics] 2024 Mar 21; Vol. 25 (1), pp. 122. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Domain Antibodies*/chemistry
Binding Sites, Antibody ; Antibodies ; Binding Sites ; Antibody Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Childhood-Onset ANCA- Associated Vasculitis: single center experience from Central California.
Autorzy:
Singh D; Division of Pediatric Rheumatology, Department of Pediatrics, Valley Children's Healthcare, Madera, CA, USA. .
Sukumaran S; Division of Pediatric Rheumatology, Department of Pediatrics, Valley Children's Healthcare, Madera, CA, USA.
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Źródło:
Pediatric rheumatology online journal [Pediatr Rheumatol Online J] 2023 Jul 03; Vol. 21 (1), pp. 66. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Granulomatosis with Polyangiitis*/drug therapy
Granulomatosis with Polyangiitis*/epidemiology
Microscopic Polyangiitis*/epidemiology
Microscopic Polyangiitis*/drug therapy
Churg-Strauss Syndrome*
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/drug therapy
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/epidemiology
Humans ; Female ; Child ; Rituximab/therapeutic use ; Antibodies, Antineutrophil Cytoplasmic ; Retrospective Studies ; Ethnicity ; Minority Groups ; Cyclophosphamide/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Coexistence of cryoglobulinemia and ANCA-associated vasculitis in a chronic brucellosis patient -a case report and literature review.
Autorzy:
Yang X; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China.
Jiao C; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China.
Liu X; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China.
Zhang Y; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China.
Zhou H; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China.
Wang Y; Department of Nephrology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, 110004, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 May 02; Vol. 23 (1), pp. 272. Date of Electronic Publication: 2023 May 02.
Typ publikacji:
Review; Case Reports; Journal Article
MeSH Terms:
Cryoglobulinemia*/complications
Cryoglobulinemia*/diagnosis
Glomerulonephritis*
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/complications
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*/diagnosis
Male ; Humans ; Middle Aged ; Antibodies, Antineutrophil Cytoplasmic/therapeutic use ; Kidney/pathology ; Hematuria/pathology ; Proteinuria/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The rise of big data: deep sequencing-driven computational methods are transforming the landscape of synthetic antibody design.
Autorzy:
Gallo E; Department of Medicinal Chemistry, Avance Biologicals, 950 Dupont Street, Toronto, ON, M6H 1Z2, Canada. .; Department of Protein Engineering, RevivAb, Av. Ipiranga, 6681, Partenon, Porto Alegre, RS, 90619-900, Brazil. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Mar 16; Vol. 31 (1), pp. 29. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Genomics*
High-Throughput Nucleotide Sequencing*
Binding Sites, Antibody
Czasopismo naukowe
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Tytuł:
Site‐Selective Tyrosine Reaction for Antibody‐Cell Conjugation and Targeted Immunotherapy.
Autorzy:
Chen, Hongfei (AUTHOR)
Wong, Hong‐Chai Fabio (AUTHOR)
Qiu, Jiaming (AUTHOR)
Li, Biquan (AUTHOR)
Yuan, Dingdong (AUTHOR)
Kong, Hao (AUTHOR)
Bao, Yishu (AUTHOR)
Zhang, Yu (AUTHOR)
Xu, Zhiyi (AUTHOR)
Tse, Ying‐Lung Steve (AUTHOR)
Xia, Jiang (AUTHOR)
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Źródło:
Advanced Science. 2/2/2024, Vol. 11 Issue 5, p1-11. 11p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme.
Autorzy:
Esparza TJ; Laboratory of Functional and Molecular Imaging, The National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, MD, 20892, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, 20892, USA.
Martin NP; Viral Vector Core, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, NC, 27709, USA.; Neurobiology Laboratory, National Institute of Environmental Health Sciences, NIH/DHHS, Research Triangle Park, NC, 27709, USA.
Anderson GP; Center for Biomolecular Science and Engineering, US Naval Research Laboratory, Washington, DC, 20375, USA.
Goldman ER; Center for Biomolecular Science and Engineering, US Naval Research Laboratory, Washington, DC, 20375, USA.
Brody DL; Laboratory of Functional and Molecular Imaging, The National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, MD, 20892, USA. .; Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Dec 22; Vol. 10 (1), pp. 22370. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Antibody Affinity*
Angiotensin-Converting Enzyme 2/*metabolism
Antibodies, Viral/*immunology
COVID-19/*metabolism
Drug Discovery/*methods
Protein Interaction Domains and Motifs/*immunology
SARS-CoV-2/*chemistry
Single-Domain Antibodies/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Angiotensin-Converting Enzyme 2/genetics ; Animals ; Antibodies, Neutralizing/immunology ; Binding Sites, Antibody/immunology ; COVID-19/therapy ; COVID-19/virology ; Camelids, New World ; HEK293 Cells ; Humans ; Immunization/methods ; Male ; Protein Binding ; Signal Transduction/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Transduction, Genetic ; Transfection
Czasopismo naukowe
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Tytuł:
Using B cell receptor lineage structures to predict affinity.
Autorzy:
Ralph DK; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Matsen FA 4th; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2020 Nov 11; Vol. 16 (11), pp. e1008391. Date of Electronic Publication: 2020 Nov 11 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibody Affinity*
Receptors, Antigen, B-Cell/*genetics
Receptors, Antigen, B-Cell/*immunology
Amino Acid Sequence ; Antigen-Antibody Reactions ; B-Lymphocytes/immunology ; Cell Lineage/genetics ; Cell Lineage/immunology ; Computational Biology ; Computer Simulation ; Consensus Sequence ; Decision Trees ; Evolution, Molecular ; High-Throughput Nucleotide Sequencing ; Humans ; Machine Learning ; Phylogeny ; Receptors, Antigen, B-Cell/chemistry
Czasopismo naukowe
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Wyświetlanie 21-40 z 282268

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