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Tytuł:
Ricin Antibodies' Neutralizing Capacity against Different Ricin Isoforms and Cultivars.
Autorzy:
Orsini Delgado ML; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Avril A; Microbiology and Infectious Diseases Department, Anti-Infectious Biotherapies and Immunity Unit, Army Biomedical Research Institute, 91220 Brétigny-sur-Orge, France.
Prigent J; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Dano J; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Rouaix A; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Worbs S; Biological Toxins, Centre for Biological Threats and Special Pathogens, Robert Koch Institute (RKI), 13353 Berlin, Germany.
Dorner BG; Biological Toxins, Centre for Biological Threats and Special Pathogens, Robert Koch Institute (RKI), 13353 Berlin, Germany.
Rougeaux C; Microbiology and Infectious Diseases Department, Anti-Infectious Biotherapies and Immunity Unit, Army Biomedical Research Institute, 91220 Brétigny-sur-Orge, France.
Becher F; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Fenaille F; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Livet S; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Volland H; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
Tournier JN; Microbiology and Infectious Diseases Department, Anti-Infectious Biotherapies and Immunity Unit, Army Biomedical Research Institute, 91220 Brétigny-sur-Orge, France.
Simon S; Paris-Saclay University, CEA, INRAE, Medicines and Healthcare Technologies Department (DMTS), SPI, 91191 Gif-sur-Yvette, France.
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Źródło:
Toxins [Toxins (Basel)] 2021 Jan 29; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 29.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Neutralizing/*pharmacology
Antidotes/*pharmacology
Poisoning/*prevention & control
Ricin/*antagonists & inhibitors
Ricinus/*metabolism
Animals ; Antibody Specificity ; Antidotes/pharmacokinetics ; Cell Survival/drug effects ; Drug Therapy, Combination ; Female ; Humans ; Jurkat Cells ; Lethal Dose 50 ; Mice, Inbred BALB C ; Poisoning/immunology ; Protein Isoforms ; Ricin/immunology ; Ricin/isolation & purification ; Ricin/poisoning ; Ricinus/growth & development ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intramuscular cobinamide as an antidote to methyl mercaptan poisoning.
Autorzy:
Hendry-Hofer TB; Department of Emergency Medicine, University of Colorado, Aurora, CO, USA.
Ng PC; Department of Emergency Medicine, University of Colorado, Aurora, CO, USA.; Brooke Army Medical Center, Ft Sam Houston, San Antonio, Texas.
McGrath AM; Department of Environmental Health and Safety, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Soules K; Department of Emergency Medicine, University of Colorado, Aurora, CO, USA.
Mukai DS; Beckman Laser Institute, University of California, Irvine, CA, USA.
Chan A; Department of Medicine, University of California, La Jolla, CA, USA.
Maddry JK; 59th Medical Wing/Science & Technology, Lackland Air Force Base, Texas, San Antonio Military Medical Center, JBSA-Ft Sam Houston, San Antonio, Texas.
White CW; Department of Pediatrics, University of Colorado, Aurora, CO, USA.
Lee J; Beckman Laser Institute, University of California, Irvine, CA, USA.
Mahon SB; Beckman Laser Institute, University of California, Irvine, CA, USA.
Brenner M; Beckman Laser Institute, University of California, Irvine, CA, USA.
Boss GR; Department of Medicine, University of California, La Jolla, CA, USA.
Bebarta VS; Department of Emergency Medicine, University of Colorado, Aurora, CO, USA.; 59th Medical Wing/Science & Technology, Lackland Air Force Base, Texas, San Antonio Military Medical Center, JBSA-Ft Sam Houston, San Antonio, Texas.
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Źródło:
Inhalation toxicology [Inhal Toxicol] 2021 Jan; Vol. 33 (1), pp. 25-32. Date of Electronic Publication: 2020 Dec 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antidotes/*pharmacology
Cobamides/*pharmacology
Sulfhydryl Compounds/*toxicity
Animals ; Antidotes/administration & dosage ; Cobamides/administration & dosage ; Female ; Inhalation Exposure ; Injections, Intramuscular ; Male ; Random Allocation ; Swine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins.
Autorzy:
Lugo MR; Department of Molecular and Cellular Biology, University of Guelph, Guelph ON N1G 2W1, Canada.
Merrill AR; Department of Molecular and Cellular Biology, University of Guelph, Guelph ON N1G 2W1, Canada.
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Źródło:
Toxins [Toxins (Basel)] 2020 Dec 25; Vol. 13 (1). Date of Electronic Publication: 2020 Dec 25.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antidotes*
Bacterial Toxins*
ADP Ribose Transferases/*toxicity
Virulence Factors/*antagonists & inhibitors
Animals ; Humans ; Virulence Factors/metabolism ; Virulence Factors/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Authors' reply to Comment on antidotal use of lipid emulsion.
Autorzy:
Mullins ME; Section of Medical Toxicology, Department of Emergency Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
Seger DL; Tennessee Poison Center, Vanderbilt University Medical Center, Nashville, TN, USA.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Dec; Vol. 58 (12), pp. 1357-1358. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji:
Letter; Comment
MeSH Terms:
Antidotes*/therapeutic use
Fat Emulsions, Intravenous*/therapeutic use
Humans ; Lipids
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comment on Antidotal use of lipid emulsion - the pendulum swings.
Autorzy:
Hoffman RS; Division of Medical Toxicology, Ronald O. Perelman Department of Emergency Medicine, NYU Grossman School of Medicine, New York, NY, USA.
Gosselin S; Department of Medicine & Emergency Medicine, McGill University Health Centre, Royal Victoria Hospital, Montreal, QC, Canada.; Hôpital Charles-Lemoyne, Greenfield Park, QC, Canada.
Villeneuve E; Department of Pharmacy, McGill University Health Centre, Montreal, QC, Canada.
Hayes BD; Department of Pharmacy, Massachusetts General Hospital, Boston, MA, USA.; Department of Emergency Medicine, Harvard Medical School, Boston, MA, USA.
Hoegberg LCG; Department of Anesthesiology, and The Danish Poisons Information Centre, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark.
Smolinske SC; New Mexico Poison & Drug Information Center, University of New Mexico, Albuquerque, NM, USA.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Dec; Vol. 58 (12), pp. 1355-1356. Date of Electronic Publication: 2020 May 13.
Typ publikacji:
Letter; Comment
MeSH Terms:
Antidotes*/therapeutic use
Fat Emulsions, Intravenous*/therapeutic use
Humans ; Lipids
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Two-bag intravenous N-acetylcysteine, antihistamine pretreatment and high plasma paracetamol levels are associated with a lower incidence of anaphylactoid reactions to N-acetylcysteine.
Autorzy:
Daoud A; Department of Clinical Medicine, Faculty of Health and Medical Science, Copenhagen University, Copenhagen, Denmark.
Dalhoff KP; Department of Clinical Medicine, Faculty of Health and Medical Science, Copenhagen University, Copenhagen, Denmark.; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Christensen MB; Department of Clinical Medicine, Faculty of Health and Medical Science, Copenhagen University, Copenhagen, Denmark.; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Bøgevig S; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
Petersen TS; Department of Clinical Medicine, Faculty of Health and Medical Science, Copenhagen University, Copenhagen, Denmark.; Department of Clinical Pharmacology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen, Denmark.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Jul; Vol. 58 (7), pp. 698-704. Date of Electronic Publication: 2019 Oct 11.
Typ publikacji:
Journal Article
MeSH Terms:
Acetaminophen/*poisoning
Acetylcysteine/*adverse effects
Anaphylaxis/*prevention & control
Antidotes/*adverse effects
Histamine Antagonists/*administration & dosage
Acetaminophen/pharmacokinetics ; Acetylcysteine/administration & dosage ; Administration, Intravenous ; Adolescent ; Adult ; Analgesics, Non-Narcotic/pharmacokinetics ; Analgesics, Non-Narcotic/poisoning ; Anaphylaxis/chemically induced ; Antidotes/administration & dosage ; Child ; Cohort Studies ; Drug Overdose/drug therapy ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Calcination Improves the In Vivo Efficacy of a Montmorillonite Clay to Bind Aflatoxin G1 in Broiler Chickens: A Toxicokinetic Approach.
Autorzy:
Rejeb R; LR18AG01, ISA-CM-BP, 47, Institut Supérieur Agronomique de Chott-Mariem, Université de Sousse, 4042 Sousse, Tunisia.; Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
Baere S; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
Devreese M; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
Ducatelle R; Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
Croubels S; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
Ayed MH; LR18AG01, ISA-CM-BP, 47, Institut Supérieur Agronomique de Chott-Mariem, Université de Sousse, 4042 Sousse, Tunisia.
Ghorbal A; Research Laboratory LR18ES33, National Engineering School of Gabes, University of Gabes, Avenue Omar Ibn El Khattab, 6029 Gabes, Tunisia.
Antonissen G; Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, 1339820 Merelbeke, Belgium.
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Źródło:
Toxins [Toxins (Basel)] 2020 Oct 18; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Dietary Supplements*
Aflatoxins/*toxicity
Animal Feed/*microbiology
Antidotes/*pharmacology
Bentonite/*pharmacology
Calcium/*pharmacology
Chelating Agents/*pharmacology
Chickens/*growth & development
Silicates/*pharmacology
Adsorption ; Aflatoxins/metabolism ; Animals ; Antidotes/metabolism ; Bentonite/metabolism ; Biological Availability ; Biotransformation ; Calcium/metabolism ; Chickens/metabolism ; Food Microbiology ; Gastrointestinal Absorption ; Silicates/metabolism ; Toxicokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antidotal Potency of the Novel, Structurally Different Adsorbents in Rats Acutely Intoxicated with the T-2 Toxin.
Autorzy:
Jaćević V; Department for Experimental Toxicology and Pharmacology, National Poison Control Centre, Military Medical Academy, 11000 Belgrade, Serbia.; Department of Pharmacological Science, Medical Faculty of the Military Medical Academy, University of Defence, 11000 Belgrade, Serbia.; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62 500 03 Hradec Králové, Czech Republic.
Dumanović J; Department of Pharmacological Science, Medical Faculty of the Military Medical Academy, University of Defence, 11000 Belgrade, Serbia.; Department of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, 11158 Belgrade, Serbia.
Lazarević M; Department for Physiology, Faculty of Veterinary Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Nepovimova E; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62 500 03 Hradec Králové, Czech Republic.
Resanović R; Institute for Poultry Disease, Faculty of Veterinary Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Milovanović Z; Special Police Unit, Police Department of the City of Belgrade, Ministry of Interior, 11030 Belgrade, Serbia.
Wu Q; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62 500 03 Hradec Králové, Czech Republic.; College of Life Science, Yangtze University, Jingzhou, Hubei 434023, China.
Kuča K; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62 500 03 Hradec Králové, Czech Republic.
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Źródło:
Toxins [Toxins (Basel)] 2020 Oct 05; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 05.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Antidotes/*pharmacology
Food Additives/*pharmacology
Poisoning/*drug therapy
T-2 Toxin/*poisoning
Adsorption ; Animals ; Antidotes/chemistry ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/pathology ; Food Additives/chemistry ; Gastric Mucosa/drug effects ; Gastric Mucosa/pathology ; Iodophors/pharmacology ; Lethal Dose 50 ; Molecular Structure ; Poisoning/pathology ; Rats, Wistar ; Structure-Activity Relationship ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fomepizole to treat disulfiram-ethanol reaction: a case series.
Autorzy:
Schicchi A; Department of Medical and Toxicological Critical Care, Federation of Toxicology APHP, Lariboisière Hospital, University of Paris, Paris, France.; Poison Control Centre and National Toxicology Information Centre - Toxicology Unit, Istituti Clinici Scientifici Maugeri, IRCCS Maugeri Hospital and University of Pavia, Pavia, Italy.
Besson H; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Rasamison R; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Berleur MP; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Mégarbane B; Department of Medical and Toxicological Critical Care, Federation of Toxicology APHP, Lariboisière Hospital, University of Paris, Paris, France.; Inserm UMRS 1144, University of Paris, Paris.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Sep; Vol. 58 (9), pp. 922-925. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Antidotes/*administration & dosage
Disulfiram/*adverse effects
Ethanol/*adverse effects
Fomepizole/*administration & dosage
Adult ; Alcohol Deterrents/administration & dosage ; Alcohol Deterrents/adverse effects ; Alcohol Drinking/prevention & control ; Alcoholism/drug therapy ; Antidotes/adverse effects ; Disulfiram/administration & dosage ; Ethanol/administration & dosage ; Female ; Fomepizole/adverse effects ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Norepinephrine/administration & dosage ; Respiration, Artificial/statistics & numerical data ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Arsenic Toxicity: Molecular Targets and Therapeutic Agents.
Autorzy:
Nurchi VM; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09124 Monserrato-Cagliari, Italy.
Djordjevic AB; Department of Toxicology 'Akademik Danilo Soldatović', Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Crisponi G; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09124 Monserrato-Cagliari, Italy.
Alexander J; Norwegian Institute of Public Health, 0213 Oslo, Norway.
Bjørklund G; Council for Nutritional and Environmental Medicine, 8610 Mo i Rana, Norway.
Aaseth J; Research Department, Innlandet Hospital Trust, 2380 Brumunddal, Norway.; IM Sechenov First Moscow State Medical University (Sechenov University), Bolshaya Pirogovskaya St., 19-1, 119146 Moscow, Russia.
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Źródło:
Biomolecules [Biomolecules] 2020 Feb 04; Vol. 10 (2). Date of Electronic Publication: 2020 Feb 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Antidotes/*therapeutic use
Arsenic/*toxicity
Arsenic Poisoning/*drug therapy
Chelating Agents/*therapeutic use
Animals ; Antidotes/chemistry ; Antidotes/pharmacology ; Arsenic/adverse effects ; Arsenic Poisoning/etiology ; Arsenic Poisoning/metabolism ; Arsenicals/adverse effects ; Chelating Agents/chemistry ; Chelating Agents/pharmacology ; Dimercaprol/analogs & derivatives ; Dimercaprol/pharmacology ; Dimercaprol/therapeutic use ; Drinking Water/adverse effects ; Humans ; Models, Molecular ; Occupational Exposure/adverse effects ; Oxidative Stress/drug effects ; Succimer/chemistry ; Succimer/pharmacology ; Succimer/therapeutic use ; Unithiol/chemistry ; Unithiol/pharmacology ; Unithiol/therapeutic use ; Water Pollutants, Chemical/adverse effects ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of fomepizole safety based on a 16-year post-marketing experience in France.
Autorzy:
Rasamison R; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Besson H; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Berleur MP; AGEPS, Pharmaceutical Establishment of Paris Hospitals, APHP, Paris, France.
Schicchi A; Department of Medical and Toxicological Critical Care, Federation of Toxicology APHP, Lariboisière Hospital, University of Paris, Paris, France.; Poison Control Centre and National Toxicology Information Centre - Toxicology Unit, Istituti Clinici Scientifici Maugeri, IRCCS Maugeri Hospital and University of Pavia, Pavia, Italy.
Mégarbane B; Department of Medical and Toxicological Critical Care, Federation of Toxicology APHP, Lariboisière Hospital, University of Paris, Paris, France.; Inserm Umrs 1144, University of Paris, Paris, France.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Jul; Vol. 58 (7), pp. 742-747. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Product Surveillance, Postmarketing*
Antidotes/*adverse effects
Fomepizole/*adverse effects
Poisoning/*drug therapy
Adult ; Antidotes/administration & dosage ; Cohort Studies ; Ethylene Glycol/poisoning ; Female ; Fomepizole/administration & dosage ; France ; Humans ; Longitudinal Studies ; Male ; Methanol/poisoning ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Is fomepizole the antidote to recommend in mass methanol outbreaks?
Autorzy:
Mégarbane B; Department of Medical and Toxicological Critical Care, Lariboisière Hospital, Inserm UMRS 1144, University of Paris, Paris, France.
Hassanian-Moghaddam H; Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Clinical Toxicology, Loghman-Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło:
Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2020 Jun; Vol. 58 (6), pp. 504. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji:
Letter; Comment
MeSH Terms:
Antidotes*
Fomepizole*
Consensus ; Disease Outbreaks ; Humans ; Methanol
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antidotal efficacies of the cyanide antidote candidate dimethyl trisulfide alone and in combination with cobinamide derivatives.
Autorzy:
Petrikovics I; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Kiss L; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Chou CE; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Ebrahimpour A; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Kovács K; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Kiss M; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Logue B; b Department of Chemistry and Biochemistry , South Dakota State University , Brookings , SD , USA.
Chan A; c Department of Medicine , University of California , San Diego , CA , USA.
Manage ABW; d Department of Mathematics and Statistics , Sam Houston State University , Huntsville , TX , USA.
Budai M; a Department of Chemistry , Sam Houston State University , Huntsville , TX , USA.
Boss GR; c Department of Medicine , University of California , San Diego , CA , USA.
Rockwood GA; e US Army Medical Research Institute of Chemical Defense , APG , MD , USA.
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Źródło:
Toxicology mechanisms and methods [Toxicol Mech Methods] 2019 Jul; Vol. 29 (6), pp. 438-444. Date of Electronic Publication: 2019 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antidotes/*therapeutic use
Cobamides/*therapeutic use
Potassium Cyanide/*poisoning
Sulfides/*therapeutic use
Animals ; Antidotes/administration & dosage ; Antidotes/chemistry ; Cobamides/administration & dosage ; Cobamides/chemistry ; Dose-Response Relationship, Drug ; Drug Compounding ; Drug Therapy, Combination ; Excipients ; Lethal Dose 50 ; Male ; Mice, Inbred Strains ; Polysorbates ; Sulfides/administration & dosage ; Sulfides/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transdermal Delivery of 2-PAM as a Tool to Increase the Effectiveness of Traditional Treatment of Organophosphate Poisoning.
Autorzy:
Vasileva L; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Gaynanova G; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Zueva I; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Lyubina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Amerhanova S; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Buzyurova D; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Babaev V; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Voloshina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Petrov K; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
Zakharova L; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, 420088 Kazan, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 30; Vol. 23 (23). Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Organophosphate Poisoning*/drug therapy
Animals ; Rats ; Administration, Cutaneous ; Acetylcholinesterase/metabolism ; Antidotes ; Surface-Active Agents/therapeutic use ; Phosphatidylcholines/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats.
Autorzy:
Sachdeva S; Division of Regulatory Toxicology, Defence Research and Development Establishment, Gwalior, India.
Sharma A; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER-R), Lucknow, India.
Flora SJS; Division of Regulatory Toxicology, Defence Research and Development Establishment, Gwalior, India.; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER-R), Lucknow, India.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Nov; Vol. 45 (6), pp. 2448-2453. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Arsenic*
Succimer*/pharmacology
Succimer*/therapeutic use
Animals ; Male ; Rats ; Antidotes/pharmacology ; Biomarkers ; Chelating Agents/pharmacology ; Glutathione Disulfide/pharmacology ; Oxidative Stress ; Rats, Wistar ; Reactive Oxygen Species ; Thiobarbituric Acid Reactive Substances ; Tungsten/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication.
Autorzy:
Rong Y; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA.
Pauly M; Mapp Biopharmaceutical, Inc. 6160 Lusk Blvd, San Diego, CA 92121, USA.
Guthals A; Mapp Biopharmaceutical, Inc. 6160 Lusk Blvd, San Diego, CA 92121, USA.
Pham H; Mapp Biopharmaceutical, Inc. 6160 Lusk Blvd, San Diego, CA 92121, USA.
Ehrbar D; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA.
Zeitlin L; Mapp Biopharmaceutical, Inc. 6160 Lusk Blvd, San Diego, CA 92121, USA.
Mantis NJ; Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA.
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Źródło:
Toxins [Toxins (Basel)] 2020 Mar 29; Vol. 12 (4). Date of Electronic Publication: 2020 Mar 29.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Antibodies, Monoclonal, Humanized/*pharmacology
Antibodies, Neutralizing/*pharmacology
Antidotes/*pharmacology
Lung Diseases/*prevention & control
Ricin/*antagonists & inhibitors
Administration, Inhalation ; Animals ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antibodies, Neutralizing/administration & dosage ; Antidotes/administration & dosage ; Chlorocebus aethiops ; Disease Models, Animal ; Drug Therapy, Combination ; Female ; Lung Diseases/chemically induced ; Mice, Inbred BALB C ; Pre-Exposure Prophylaxis ; Ricin/immunology ; Vero Cells
Czasopismo naukowe
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Tytuł:
Pralidoxime administered during cardiopulmonary resuscitation facilitates successful resuscitation in a pig model of cardiac arrest.
Autorzy:
Jung YH; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
Lee HY; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.
Jeung KW; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
Lee BK; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
Youn CS; Department of Emergency Medicine, Seoul St. Mary's Hospital, Seoul, Korea.
Yun SW; Department of Emergency Medical Technology, Namseoul University, Cheonan, Korea.
Heo T; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
Min YI; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, Korea.; Department of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Feb; Vol. 47 (2), pp. 236-246. Date of Electronic Publication: 2019 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Antidotes/*therapeutic use
Cardiopulmonary Resuscitation/*methods
Heart Arrest/*drug therapy
Pralidoxime Compounds/*therapeutic use
Animals ; Antidotes/pharmacology ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Cross-Over Studies ; Heart Arrest/physiopathology ; Heart Rate/drug effects ; Heart Rate/physiology ; Pralidoxime Compounds/pharmacology ; Prospective Studies ; Rats ; Rats, Wistar ; Swine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 41-60 z 4041

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