Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Antigen-Presenting Cells"" wg kryterium: Temat


Tytuł :
[Stimulatory and inhibitory signaling pathways of the T cell-APC interaction and the effect of TLR agonists on APCs].
Autorzy :
Kürten CHL; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Deuß E; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Lei YL; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Höing B; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Kramer B; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Mannheim, Universität Heidelberg, Mannheim, Deutschland.
Lang S; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland.
Ferris RL; Cancer Immunology Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Kansy BA; Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland. .
Pokaż więcej
Transliterated Title :
Stimulierende und inhibierende Signalwege der APZ- und T-Zell-Interaktion sowie Einfluss von TLR-Agonisten auf APZ.
Źródło :
HNO [HNO] 2020 Dec; Vol. 68 (12), pp. 916-921. Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Antigen-Presenting Cells*
CD8-Positive T-Lymphocytes*
Signal Transduction*
Toll-Like Receptors*/antagonists & inhibitors
B7-H1 Antigen/metabolism ; NF-kappa B/physiology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection.
Autorzy :
Horman WSJ; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC, Australia.; Commonwealth Scientific and Industrial Research Organisation Health and Biosecurity, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Nguyen THO; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC, Australia.
Kedzierska K; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC, Australia.
Butler J; Commonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Shan S; Commonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Layton R; Commonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Bingham J; Commonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Payne J; Commonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Bean AGD; Commonwealth Scientific and Industrial Research Organisation Health and Biosecurity, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Layton DS; Commonwealth Scientific and Industrial Research Organisation Health and Biosecurity, Australian Centre for Disease Prevention, East Geelong, VIC, Australia.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2020 Sep 24; Vol. 11, pp. 559113. Date of Electronic Publication: 2020 Sep 24 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*immunology
CD8-Positive T-Lymphocytes/*immunology
Host-Pathogen Interactions/*immunology
Influenza A Virus, H7N9 Subtype/*physiology
Orthomyxoviridae Infections/*immunology
Animals ; Antigen-Presenting Cells/pathology ; Betacoronavirus/immunology ; CD8-Positive T-Lymphocytes/pathology ; COVID-19 ; Coronavirus Infections/immunology ; Disease Models, Animal ; Ferrets ; Humans ; Orthomyxoviridae Infections/pathology ; Pandemics ; Pneumonia, Viral/immunology ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
The Expression of Adenosine A2B Receptor on Antigen-Presenting Cells Suppresses CD8 T-cell Responses and Promotes Tumor Growth.
Autorzy :
Chen S; Robert H. Lurie Comprehensive Cancer Center, Department of Medicine-Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Akdemir I; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.
Fan J; Robert H. Lurie Comprehensive Cancer Center, Department of Medicine-Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Linden J; Division of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, California.
Zhang B; Robert H. Lurie Comprehensive Cancer Center, Department of Medicine-Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. .
Cekic C; Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey. .; Division of Inflammation Biology, La Jolla Institute for Immunology, La Jolla, California.
Pokaż więcej
Źródło :
Cancer immunology research [Cancer Immunol Res] 2020 Aug; Vol. 8 (8), pp. 1064-1074. Date of Electronic Publication: 2020 May 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*immunology
CD8-Positive T-Lymphocytes/*immunology
Myeloid Cells/*immunology
Neoplasms/*immunology
Receptor, Adenosine A2B/*metabolism
Animals ; Antigen-Presenting Cells/metabolism ; Cell Line, Tumor ; Disease Models, Animal ; Immune Tolerance ; Mice ; Mice, Knockout ; Myeloid Cells/metabolism ; Neoplasms/metabolism ; Neoplasms/pathology ; Receptor, Adenosine A2B/genetics ; Receptor, Adenosine A2B/immunology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain.
Autorzy :
Rostami J; Molecular Geriatrics, Department of Public Health and Caring Sciences/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden.
Fotaki G; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85, Uppsala, Sweden.
Sirois J; Neuroimmunology Unit, department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, 3801, Canada.
Mzezewa R; Molecular Geriatrics, Department of Public Health and Caring Sciences/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden.
Bergström J; Molecular Geriatrics, Department of Public Health and Caring Sciences/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden.
Essand M; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85, Uppsala, Sweden.
Healy L; Neuroimmunology Unit, department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, 3801, Canada.
Erlandsson A; Molecular Geriatrics, Department of Public Health and Caring Sciences/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, SE-751 85, Uppsala, Sweden. .
Pokaż więcej
Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2020 Apr 16; Vol. 17 (1), pp. 119. Date of Electronic Publication: 2020 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Astrocytes/*metabolism
Brain/*metabolism
Microglia/*metabolism
Parkinson Disease/*metabolism
Aged ; Aged, 80 and over ; Antigen-Presenting Cells/immunology ; Antigen-Presenting Cells/pathology ; Astrocytes/immunology ; Astrocytes/pathology ; Brain/immunology ; Brain/pathology ; Cells, Cultured ; Female ; Humans ; Male ; Microglia/immunology ; Microglia/pathology ; Middle Aged ; Parkinson Disease/immunology ; Parkinson Disease/pathology
Czasopismo naukowe
Tytuł :
Biomimic strategies for modulating the interaction between particle adjuvants and antigen-presenting cells.
Autorzy :
Wu J; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P.R. China. .
Ma G
Pokaż więcej
Źródło :
Biomaterials science [Biomater Sci] 2020 May 07; Vol. 8 (9), pp. 2366-2375. Date of Electronic Publication: 2020 Mar 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adjuvants, Immunologic*
Antigen-Presenting Cells*
Animals ; Biomimetics ; Humans
Czasopismo naukowe
Tytuł :
An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen-Presenting Cells, in the Presence or Absence of Bone Marrow Mesenchymal Stem Cells (MSCs).
Autorzy :
Pedroso JF; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
de Souza Valim V; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.
Pezzi A; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Furlan JM; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.
Lenhart G; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Sehn F; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Zambonato B; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Gonçalves AD; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Wilke I; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Amorin B; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
da Silva MA; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil.
Pedrazzani FS; Personalized Diagnostic Unit, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
da Rocha Silla LM; Cellular Technology and Therapy Center, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, CEP 90035-903, Brazil. .; Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil. .
Pokaż więcej
Źródło :
Molecular biotechnology [Mol Biotechnol] 2020 May; Vol. 62 (5), pp. 306-315.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Antigen-Presenting Cells/*cytology
Killer Cells, Natural/*cytology
Leukocytes, Mononuclear/*cytology
Mesenchymal Stem Cells/*cytology
Antigen-Presenting Cells/immunology ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; GPI-Linked Proteins/metabolism ; Gene Expression Regulation ; Healthy Volunteers ; Humans ; Interleukin-2/metabolism ; K562 Cells ; Killer Cells, Natural/immunology ; Leukocytes, Mononuclear/immunology ; Mesenchymal Stem Cells/immunology ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Receptors, IgG/metabolism
Czasopismo naukowe
Tytuł :
Glycogen synthase kinase 3 (GSK-3) controls T-cell motility and interactions with antigen presenting cells.
Autorzy :
Taylor A; Leeds Institute of Medical Research, School of Medicine, University of Leeds, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, LS9 7TF, UK. .; Cell Signalling Section, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1Q, UK. .
Rudd CE; Cell Signalling Section, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1Q, UK. .; Division of Immunology-Oncology Research Center, Maisonneuve-Rosemont Hospital, Montreal, QC, H1T 2M4, Canada. .; Département de Medicine, Université de Montréal, Montreal, QC, H3C 3J7, Canada. .
Pokaż więcej
Źródło :
BMC research notes [BMC Res Notes] 2020 Mar 18; Vol. 13 (1), pp. 163. Date of Electronic Publication: 2020 Mar 18.
Typ publikacji :
Journal Article
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Cell Movement/*physiology
Glycogen Synthase Kinase 3/*metabolism
T-Lymphocytes, Cytotoxic/*metabolism
Aminophenols/pharmacology ; Animals ; Antigen-Presenting Cells/drug effects ; Cell Movement/drug effects ; Glycogen Synthase Kinase 3/antagonists & inhibitors ; Maleimides/pharmacology ; Mice ; Mice, Inbred C57BL ; T-Lymphocytes, Cytotoxic/drug effects
Czasopismo naukowe
Tytuł :
Cytoskeletal tension actively sustains the migratory T-cell synaptic contact.
Autorzy :
Kumari S; Koch Institute of Integrative Research, MIT, Cambridge, MA, USA.; Ragon Institute of Harvard, MIT and MGH, Cambridge, MA, USA.
Mak M; Department of Mechanical Engineering, MIT, Cambridge, MA, USA.
Poh YC; Koch Institute of Integrative Research, MIT, Cambridge, MA, USA.; Department of Mechanical Engineering, MIT, Cambridge, MA, USA.
Tohme M; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Watson N; Whitehead Institute of Biomedical Research, Cambridge, MA, USA.
Melo M; Koch Institute of Integrative Research, MIT, Cambridge, MA, USA.; Ragon Institute of Harvard, MIT and MGH, Cambridge, MA, USA.
Janssen E; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Dustin M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Geha R; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Irvine DJ; Koch Institute of Integrative Research, MIT, Cambridge, MA, USA.; Ragon Institute of Harvard, MIT and MGH, Cambridge, MA, USA.; Department of Biological Engineering, MIT, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Pokaż więcej
Źródło :
The EMBO journal [EMBO J] 2020 Mar 02; Vol. 39 (5), pp. e102783. Date of Electronic Publication: 2020 Jan 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Immunological Synapses/*metabolism
Wiskott-Aldrich Syndrome/*metabolism
Wiskott-Aldrich Syndrome Protein/*metabolism
Actin Cytoskeleton/metabolism ; Actins/metabolism ; Animals ; Antigen-Presenting Cells/immunology ; Cell Movement ; Cytoskeleton/metabolism ; Humans ; Lymphocyte Activation ; Male ; Mice ; Mice, Inbred C57BL ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Wiskott-Aldrich Syndrome/immunology ; Wiskott-Aldrich Syndrome Protein/genetics
Czasopismo naukowe
Tytuł :
Pancreatic β-cells express major histocompatibility complex class II: Do diabetic β-cells have the capacity of antigen-presenting cells?
Autorzy :
Sano H; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.
Imagawa A; Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Japan.
Pokaż więcej
Źródło :
Journal of diabetes investigation [J Diabetes Investig] 2020 Mar; Vol. 11 (2), pp. 281-283. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Antigen-Presenting Cells/*immunology
Diabetes Mellitus, Type 1/*immunology
Histocompatibility Antigens Class II/*immunology
Insulin-Secreting Cells/*immunology
Antigen-Presenting Cells/metabolism ; Diabetes Mellitus, Type 1/metabolism ; Histocompatibility Antigens Class II/metabolism ; Humans ; Insulin-Secreting Cells/metabolism
Czasopismo naukowe
Tytuł :
Activation and expansion of human T cells using artificial antigen-presenting cell scaffolds.
Autorzy :
Zhang DKY; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; The Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA.
Cheung AS; Immulus, Inc., Oakland, CA, USA.
Mooney DJ; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA. .; The Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA. .
Pokaż więcej
Źródło :
Nature protocols [Nat Protoc] 2020 Mar; Vol. 15 (3), pp. 773-798. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antigen-Presenting Cells*
T-Lymphocytes*
Cell Lineage ; Cloning, Molecular ; Gene Expression Regulation ; Humans
Czasopismo naukowe
Tytuł :
Biotin Functionalized Self-Assembled Peptide Nanofiber as an Adjuvant for Immunomodulatory Response.
Autorzy :
Demircan MB; Neuroscience Graduate Program, Bilkent University, Ankara, 06800, Turkey.; Department of Internal Medicine II, Hematology and Oncology, Friedrich-Schiller-University Medical Center, Jena, 07743, Germany.; Leibniz-Institute on Aging, Fritz-Lipmann-Institute, Jena, 07745, Germany.
Tohumeken S; Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, 06800, Turkey.; Division of Hematologic Malignancies, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
Gunduz N; Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, 06800, Turkey.; The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.
Khalily MA; Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, 06800, Turkey.
Tekinay T; Gazi University, Ankara, 06100, Turkey.
Guler MO; The Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, 60637, USA.
Tekinay AB; Neuroscience Graduate Program, Bilkent University, Ankara, 06800, Turkey.; Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, 06800, Turkey.; Eryigit Research & Development Center, Ivedik OSB, Ankara, 06100, Turkey.
Pokaż więcej
Źródło :
Biotechnology journal [Biotechnol J] 2020 Dec; Vol. 15 (12), pp. e2000100. Date of Electronic Publication: 2020 Jul 26.
Typ publikacji :
Journal Article
MeSH Terms :
Adjuvants, Immunologic/*chemistry
Nanofibers/*chemistry
Peptides/*chemistry
Peptides/*immunology
Adjuvants, Immunologic/administration & dosage ; Animals ; Antigen Presentation ; Antigen-Presenting Cells/cytology ; Antigen-Presenting Cells/immunology ; Antigens/administration & dosage ; Antigens/chemistry ; Biocompatible Materials/chemistry ; Biotechnology ; Biotin/analogs & derivatives ; Cytokines/metabolism ; Drug Design ; Immunity, Cellular ; Immunity, Humoral ; In Vitro Techniques ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Nanofibers/administration & dosage ; Nanofibers/ultrastructure ; Ovalbumin/administration & dosage ; Ovalbumin/immunology ; Peptides/administration & dosage ; Protein Engineering
Czasopismo naukowe
Tytuł :
Potential role of exosome-based allorecognition pathways involved in lung transplant rejection.
Autorzy :
Hwang B; Department of Surgery, University of Washington School of Medicine, Seattle, Wash; Center for Lung Biology, University of Washington, Seattle, Wash; West Coast Exosortium (WestCo Exosortium), Seattle, Wash. Electronic address: .
Bryers J; Center for Lung Biology, University of Washington, Seattle, Wash; West Coast Exosortium (WestCo Exosortium), Seattle, Wash; Department of Bioengineering, University of Washington, Seattle, Wash.
Mulligan MS; Department of Surgery, University of Washington School of Medicine, Seattle, Wash; Center for Lung Biology, University of Washington, Seattle, Wash; West Coast Exosortium (WestCo Exosortium), Seattle, Wash; Department of Medicine, University of Washington School of Medicine, Seattle, Wash.
Pokaż więcej
Źródło :
The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2021 Feb; Vol. 161 (2), pp. e129-e134. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Exosomes/*metabolism
Graft Rejection/*metabolism
Lung/*immunology
Lung Transplantation/*adverse effects
Adaptive Immunity ; Animals ; Antigen-Presenting Cells/immunology ; Exosomes/immunology ; Graft Rejection/immunology ; Humans ; Immunity, Innate
Czasopismo naukowe
Tytuł :
In vitro elimination of autoreactive B cells from rheumatoid arthritis patients by universal chimeric antigen receptor T cells.
Autorzy :
Zhang B; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.; Clinical Immunology Center& Epigenetics Center, Peking Union Medical College Hospital, Chinese Academy of MedicalSciences and Peking Union Medical College, Beijing, China.
Wang Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Yuan Y; Clinical Immunology Center& Epigenetics Center, Peking Union Medical College Hospital, Chinese Academy of MedicalSciences and Peking Union Medical College, Beijing, China.
Sun J; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Liu L; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Huang D; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hu J; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Clinical Immunology Center& Epigenetics Center, Peking Union Medical College Hospital, Chinese Academy of MedicalSciences and Peking Union Medical College, Beijing, China.
Wang M; Clinical Immunology Center& Epigenetics Center, Peking Union Medical College Hospital, Chinese Academy of MedicalSciences and Peking Union Medical College, Beijing, China.; Department of Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Li S; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Song W; Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chen H; Department of Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhou D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China .
Zhang X; Clinical Immunology Center& Epigenetics Center, Peking Union Medical College Hospital, Chinese Academy of MedicalSciences and Peking Union Medical College, Beijing, China .; Department of Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Pokaż więcej
Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Feb; Vol. 80 (2), pp. 176-184. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arthritis, Rheumatoid/*therapy
Fluorescein-5-isothiocyanate/*therapeutic use
Immunotherapy, Adoptive/*methods
Receptors, Antigen, T-Cell/*therapeutic use
Receptors, Chimeric Antigen/*therapeutic use
Adult ; Antigen-Presenting Cells/immunology ; Arthritis, Rheumatoid/immunology ; Autoantigens/immunology ; B-Lymphocytes/immunology ; Collagen Type II/immunology ; Epitopes/immunology ; Female ; Fibrinogen/immunology ; Humans ; Ligands ; Male ; Peptides, Cyclic/immunology ; Proof of Concept Study ; Tenascin/immunology ; Vimentin/immunology
Czasopismo naukowe
Tytuł :
CERI, CEFX, and CPI: Largely Improved Positive Controls for Testing Antigen-Specific T Cell Function in PBMC Compared to CEF.
Autorzy :
Lehmann AA; Cellular Technology Ltd., Shaker Heights, OH 44122, USA.
Reche PA; Laboratorio de Inmunomedicina & Inmunoinformatica, Departamento de Inmunologia & O2, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Zhang T; Cellular Technology Ltd., Shaker Heights, OH 44122, USA.
Suwansaard M; Cellular Technology Ltd., Shaker Heights, OH 44122, USA.
Lehmann PV; Cellular Technology Ltd., Shaker Heights, OH 44122, USA.
Pokaż więcej
Źródło :
Cells [Cells] 2021 Jan 27; Vol. 10 (2). Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Leukocytes, Mononuclear/*immunology
Antigen-Presenting Cells/immunology ; Antigens/immunology ; Humans ; Immunologic Tests/methods ; Peptides/immunology
Czasopismo naukowe
Tytuł :
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis.
Autorzy :
Krienke C; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.
Kolb L; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Diken E; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Streuber M; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Kirchhoff S; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Bukur T; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Akilli-Öztürk Ö; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.
Kranz LM; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Berger H; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Petschenka J; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Cancer Immunology and Immune Modulation, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riss, Germany.
Diken M; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Kreiter S; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Yogev N; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University, Mainz 55131, Germany.; Clinic and Polyclinic for Dermatology and Venereology, University Hospital Cologne, Kerpenerstr. 62, Cologne 50937, Germany.
Waisman A; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University, Mainz 55131, Germany.
Karikó K; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Türeci Ö; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.; CI3 - Cluster for Individualized Immunointervention e.V., Hölderlinstraße 8, 55131 Mainz, Germany.
Sahin U; TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Freiligrathstr. 12, Mainz 55131, Germany. .; Research Center for Immunotherapy (FZI), University Medical Center at the Johannes Gutenberg University, Langenbeckstr. 1, Mainz 55131, Germany.; Biopharmaceutical New Technologies (BioNTech) Corporation, An der Goldgrube 12, Mainz 55131, Germany.
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2021 Jan 08; Vol. 371 (6525), pp. 145-153.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bystander Effect/*immunology
Encephalomyelitis, Autoimmune, Experimental/*therapy
Immunosuppression/*methods
Multiple Sclerosis/*therapy
Vaccines, Synthetic/*therapeutic use
Animals ; Antigen-Presenting Cells ; Autoantigens/genetics ; Inflammation/immunology ; Mice ; Mice, Inbred C57BL ; Pseudouridine/analogs & derivatives ; Pseudouridine/chemistry ; RNA, Messenger/adverse effects ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; T-Lymphocytes, Regulatory/immunology ; Vaccines, Synthetic/adverse effects
Czasopismo naukowe
Tytuł :
Signaling from membrane semaphorin 4D in T lymphocytes.
Autorzy :
Kuklina E; Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, 614081, Perm, Russia. Electronic address: .
Nekrasova I; Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, 614081, Perm, Russia.
Glebezdina N; Perm Federal Research Center, Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, 614081, Perm, Russia.
Pokaż więcej
Źródło :
Molecular immunology [Mol Immunol] 2021 Jan; Vol. 129, pp. 56-62. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*immunology
Cell Membrane/*immunology
Semaphorins/*immunology
Signal Transduction/*immunology
T-Lymphocytes/*immunology
Antigen-Presenting Cells/immunology ; B-Lymphocytes/immunology ; Cell Line ; Humans ; Lymphocyte Activation/immunology ; Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/immunology ; Phosphorylation/immunology ; ZAP-70 Protein-Tyrosine Kinase/immunology
Czasopismo naukowe
Tytuł :
Distinguishing human peripheral blood CD16 myeloid cells based on phenotypic characteristics.
Autorzy :
Fromm PD; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Silveira PA; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Hsu JL; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.
Papadimitrious MS; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Lo TH; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Ju X; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Kupresanin F; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.
Romano A; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Department of Pathology, The University of Sydney, Sydney, New South Wales, Australia.
Hsu WH; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Bryant CE; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Kong B; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Abadir E; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.
Mekkawy A; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.
M McGuire H; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Department of Pathology, The University of Sydney, Sydney, New South Wales, Australia.
Groth BFS; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Department of Pathology, The University of Sydney, Sydney, New South Wales, Australia.
Cunningham I; Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Newman E; Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Gibson J; Institute of Haematology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Hogarth PM; Immune Therapies Group, Burnet Institute, Melbourne, Victoria, Australia.
Hart DNJ; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Institute of Haematology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Clark GJ; Dendritic Cell Research, ANZAC Research Institute, Sydney, New South Wales, Australia.; Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Department of Haematology, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.
Pokaż więcej
Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Feb; Vol. 107 (2), pp. 323-339. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*immunology
Biomarkers/*analysis
Dendritic Cells/*immunology
Graft vs Host Disease/*immunology
Monocytes/*immunology
Myeloid Cells/*immunology
Receptors, IgG/*metabolism
Antigen-Presenting Cells/metabolism ; Antigens, Surface/metabolism ; Cell Differentiation ; Cell Lineage ; Dendritic Cells/metabolism ; GPI-Linked Proteins/metabolism ; Graft vs Host Disease/diagnosis ; Graft vs Host Disease/metabolism ; HLA-DR Antigens/metabolism ; Hematopoietic Stem Cell Transplantation ; Humans ; Lectins, C-Type/metabolism ; Leukemia, Myeloid, Acute/immunology ; Leukemia, Myeloid, Acute/therapy ; Membrane Glycoproteins/metabolism ; Monocytes/metabolism ; Multiple Myeloma/immunology ; Multiple Myeloma/therapy ; Myeloid Cells/metabolism ; Receptors, CCR5/metabolism ; Receptors, Cell Surface/metabolism ; Transplantation, Homologous
Czasopismo naukowe
Tytuł :
LTA1 and dmLT enterotoxin-based proteins activate antigen-presenting cells independent of PKA and despite distinct cell entry mechanisms.
Autorzy :
Valli E; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, United States of America.
Baudier RL; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, United States of America.
Harriett AJ; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, United States of America.
Norton EB; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 Jan 13; Vol. 15 (1), pp. e0227047. Date of Electronic Publication: 2020 Jan 13 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Enterotoxins/*pharmacology
Lipopolysaccharides/*pharmacology
Teichoic Acids/*pharmacology
Adjuvants, Immunologic ; Antigen-Presenting Cells/drug effects ; Cell Line ; Cell Membrane Permeability ; Cells, Cultured ; Cyclic AMP-Dependent Protein Kinases ; Cytokines/drug effects ; Cytokines/metabolism ; Enterotoxins/immunology ; Humans ; Inflammasomes/drug effects ; Inflammasomes/metabolism ; Lipopolysaccharides/immunology ; Monocytes/pathology ; THP-1 Cells ; Teichoic Acids/immunology
Czasopismo naukowe
Tytuł :
Population-Specific Metabolic Alterations in Professional Antigen-Presenting Cells Contribute to Sepsis-Associated Immunosuppression.
Autorzy :
Schenz J; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Tamulyte S; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Nusshag C; Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.
Brenner T; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Poschet G; Metabolomics Core Technology Platform, University of Heidelberg, Heidelberg, Germany.
Weigand MA; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Uhle F; Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Pokaż więcej
Źródło :
Shock (Augusta, Ga.) [Shock] 2020 Jan; Vol. 53 (1), pp. 5-15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigen-Presenting Cells/*metabolism
Sepsis/*metabolism
Antigen-Presenting Cells/immunology ; B-Lymphocytes/metabolism ; Cytokines/blood ; Flow Cytometry ; Glycolysis/physiology ; Humans ; Immunoglobulins/blood ; Immunosuppression ; Leukocytes, Mononuclear/metabolism ; Sepsis/immunology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies