Temat: "Antigens, CD" - OpacWWW

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Tytuł:: TIM-3/CD68 double-high expression in Glioma: Prognostic characteristics and potential therapeutic approaches.
Autorzy:: Hu W; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, PR China; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China.
Li D; Department of Neurosurgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China.
Yang Y; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, PR China; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China.
Zheng Y; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China.
Zeng J; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, PR China; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China. Electronic address: .
Sai K; Department of Neurosurgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China; State Key Laboratory of Oncology in South China, Guangzhou, PR China; Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, PR China. Electronic address: .; Pokaż więcej
Źródło:: International immunopharmacology [Int Immunopharmacol] 2024 Sep 30; Vol. 139, pp. 112665. Date of Electronic Publication: 2024 Jul 12.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatitis A Virus Cellular Receptor 2*/metabolism
Hepatitis A Virus Cellular Receptor 2*/genetics
Glioma*/metabolism
Glioma*/therapy
Glioma*/genetics
Glioma*/mortality
Glioma*/diagnosis
Brain Neoplasms*/metabolism
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Brain Neoplasms*/mortality
Antigens, Differentiation, Myelomonocytic*/metabolism
Antigens, Differentiation, Myelomonocytic*/genetics
Antigens, CD*/metabolism
Antigens, CD*/genetics
Tumor Microenvironment*/immunology
Biomarkers, Tumor*/metabolism
Biomarkers, Tumor*/genetics
Humans ; Prognosis ; Female ; Male ; Middle Aged ; Immunotherapy/methods ; Adult ; Macrophages/immunology ; Macrophages/metabolism ; Gene Expression Regulation, Neoplastic ; CD68 Molecule

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Tytuł:: Regulation of KLRC and Ceacam gene expression by miR-141 supports cell proliferation and metastasis in cervical cancer cells.
Autorzy:: Dabous E; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Alalem M; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Awad AM; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Elawdan KA; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Tabl AM; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Elsaka S; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Said W; Microbiology and Chemistry Department, Faculty of Science, Benha University, Benha, Egypt.
Guirgis AA; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt.
Khalil H; Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, P.O Box 79, Sadat City, Egypt. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2024 Sep 03; Vol. 24 (1), pp. 1091. Date of Electronic Publication: 2024 Sep 03.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/genetics
Uterine Cervical Neoplasms*/genetics
Uterine Cervical Neoplasms*/pathology
Uterine Cervical Neoplasms*/metabolism
Cell Proliferation*/genetics
Gene Expression Regulation, Neoplastic*
Cell Adhesion Molecules*/genetics
Cell Adhesion Molecules*/metabolism
Antigens, CD*/genetics
Antigens, CD*/metabolism
Humans ; HeLa Cells ; Female ; Neoplasm Metastasis ; Cell Line, Tumor ; Receptors, Immunologic/genetics ; Receptors, Immunologic/metabolism ; Cell Movement/genetics

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Tytuł:: PRRSV infection facilitates the shedding of soluble CD163 to induce inflammatory responses.
Autorzy:: Liu J; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.
Su G; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.
Chen X; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.
Chen Q; Center of Animal Laboratory, Xuzhou Medical University, Xuzhou 221000, China; School of Life Sciences, Xuzhou Medical University, Xuzhou 221000, China.
Duan C; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.
Xiao S; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.
Zhou Y; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China. Electronic address: .
Fang L; National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, the Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China. Electronic address: .; Pokaż więcej
Źródło:: Veterinary microbiology [Vet Microbiol] 2024 Sep; Vol. 296, pp. 110189. Date of Electronic Publication: 2024 Jul 20.
Typ publikacji:: Journal Article
MeSH Terms:: Antigens, Differentiation, Myelomonocytic*/genetics
Antigens, Differentiation, Myelomonocytic*/immunology
Antigens, Differentiation, Myelomonocytic*/metabolism
Receptors, Cell Surface*/genetics
Receptors, Cell Surface*/metabolism
Porcine respiratory and reproductive syndrome virus*/immunology
Antigens, CD*/genetics
Antigens, CD*/metabolism
Antigens, CD*/immunology
Porcine Reproductive and Respiratory Syndrome*/immunology
Porcine Reproductive and Respiratory Syndrome*/virology
Macrophages, Alveolar*/virology
Macrophages, Alveolar*/immunology
Inflammation*/virology
Animals ; Swine ; Cell Line

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Tytuł:: Progesterone receptor impairs immune respond and down-regulates sensitivity to anti-LAG3 in breast cancer.
Autorzy:: Xiao Y; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Zheng P; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Xu W; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Wu Z; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Zhang X; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Wang R; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China.
Huang T; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China. Electronic address: .
Ming J; Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, Hubei 430022, China. Electronic address: .; Pokaż więcej
Źródło:: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2024 Sep; Vol. 271, pp. 68-78. Date of Electronic Publication: 2024 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Progesterone*/metabolism
Breast Neoplasms*/immunology
Breast Neoplasms*/pathology
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Lymphocyte Activation Gene 3 Protein*
Mice, Inbred BALB C*
Down-Regulation*
Antigens, CD*/metabolism
Antigens, CD*/genetics
Female ; Animals ; Humans ; Cell Line, Tumor ; Mice ; Tumor Microenvironment/immunology ; CD8-Positive T-Lymphocytes/immunology

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Tytuł:: Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A .
Autorzy:: Ming Q; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Antfolk D; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Price DA; Washington University School of Medicine, Department of Medicine, St. Louis, MO, 63110, USA.
Manturova A; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Medina E; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Singh S; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Mason C; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA.
Tran TH; Moffitt Cancer Center and Research Institute, Chemical Biology Core, Tampa, FL, 33612, USA.
Smalley KSM; Moffitt Cancer Center and Research Institute, Department of Tumor Microenvironment and Metastasis, Tampa, FL, 33612, USA.
Leung DW; Washington University School of Medicine, Department of Medicine, St. Louis, MO, 63110, USA.
Luca VC; Moffitt Cancer Center and Research Institute, Department of Immunology, Tampa, FL, 33612, USA. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2024 Aug 29; Vol. 15 (1), pp. 7513. Date of Electronic Publication: 2024 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Lymphocyte Activation Gene 3 Protein*
Histocompatibility Antigens Class II*/metabolism
Histocompatibility Antigens Class II*/chemistry
Histocompatibility Antigens Class II*/immunology
Antigens, CD*/metabolism
Antigens, CD*/chemistry
Antigens, CD*/immunology
Protein Binding*
Animals ; Mice ; Binding Sites ; Crystallography, X-Ray ; Humans ; Models, Molecular ; Lymphocyte Activation ; CD4 Antigens/metabolism ; CD4 Antigens/chemistry ; CD4 Antigens/immunology ; Protein Domains

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Tytuł:: Notch transcriptional target tmtc1 maintains vascular homeostasis.
Autorzy:: Paik NY; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Neethling J; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Anwar M; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Gupta P; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Sanborn MA; Department of Biochemistry, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Shen Z; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Bandara T; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Hyun J; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Naiche LA; Department of Physiology and Biophysics, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Kitajewski JK; Department of Physiology and Biophysics, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Rehman J; Department of Biochemistry, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Shin JW; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Mehta D; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Pajcini KV; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA. .; Pokaż więcej
Źródło:: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Aug 27; Vol. 81 (1), pp. 370. Date of Electronic Publication: 2024 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/metabolism
Cadherins*/genetics
Homeostasis*
Endothelial Cells*/metabolism
Signal Transduction*
Lung*/metabolism
Lung*/blood supply
Antigens, CD*/metabolism
Antigens, CD*/genetics
Animals ; Mice ; Humans ; Receptors, Notch/metabolism ; Receptors, Notch/genetics ; Mice, Transgenic ; Capillary Permeability ; Receptor, Notch1/metabolism ; Receptor, Notch1/genetics ; Adherens Junctions/metabolism ; Mice, Inbred C57BL

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Tytuł:: Insights into E-Cadherin Impairment in CDH1 -Unaltered Invasive Lobular Carcinoma: A Comprehensive Bioinformatic Study.
Autorzy:: Uchida S; Division of Diagnostic Pathology, Kikuna Memorial Hospital, 4-4-27, Kikuna, Kohoku-ku, Yokohama 222-0011, Japan.; Division of Pathology, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.; Department of Human Pathology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 17; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/genetics
Cadherins*/metabolism
Carcinoma, Lobular*/genetics
Carcinoma, Lobular*/metabolism
Carcinoma, Lobular*/pathology
Antigens, CD*/metabolism
Antigens, CD*/genetics
Computational Biology*/methods
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Breast Neoplasms*/metabolism
Gene Expression Regulation, Neoplastic*
DNA Methylation*
Humans ; Female ; Mutation ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Neoplasm Invasiveness

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Tytuł:: Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.
Autorzy:: Bessa P; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Newman AG; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Yan K; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Schaub T; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Dannenberg R; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Lajkó D; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Eilenberger J; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Brunet T; Department of Pediatric Neurology and Developmental Medicine and Ludwig Maximilians University Center for Children with Medical Complexity, Dr. von Hauner Children's Hospital, Ludwig Maximilians University Hospital, Ludwig Maximilians University, Munich, Germany.; Institute of Human Genetics, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
Textoris-Taube K; Institute of Biochemistry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115, Berlin, Germany.; Core Facility - High-Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Core Facility - High-Throughput Mass Spectrometry, Am Charitéplatz 1, Berlin, Germany.
Kemmler E; Institute of Physiology, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115, Berlin, Germany.
Deng P; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Banerjee P; Institute of Physiology, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115, Berlin, Germany.
Ravindran E; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Preissner R; Institute of Physiology, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115, Berlin, Germany.
Rosário M; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Tarabykin V; Institute of Cell Biology and Neurobiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. .; Institute of Neuroscience, Lobachevsky University of Nizhny Novgorod, Nizhny Novgorod, 603950, Russian Federation. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2024 Aug 16; Vol. 15 (1), pp. 7059. Date of Electronic Publication: 2024 Aug 16.
Typ publikacji:: Journal Article
MeSH Terms:: Semaphorins*/metabolism
Semaphorins*/genetics
Neocortex*/metabolism
Cell Membrane*/metabolism
Matrix Attachment Region Binding Proteins*/metabolism
Matrix Attachment Region Binding Proteins*/genetics
Antigens, CD*/metabolism
Antigens, CD*/genetics
Protein Multimerization*
Transcription Factors*/metabolism
Transcription Factors*/genetics
Neurons*/metabolism
Animals ; Humans ; Mice ; Mutation ; Cell Movement ; Axons/metabolism ; Epilepsy/metabolism ; Epilepsy/genetics ; Corpus Callosum/metabolism ; HEK293 Cells ; Glycosylation ; Male ; Female ; Mice, Inbred C57BL

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Tytuł:: Neisserial adhesin A (NadA) binds human Siglec-5 and Siglec-14 with high affinity and promotes bacterial adhesion/invasion.
Autorzy:: Benucci B; GSK, Siena, Italy.
Spinello Z; GSK, Siena, Italy.
Calvaresi V; GSK, Siena, Italy.; Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark.
Viviani V; GSK, Siena, Italy.
Perrotta A; GSK, Siena, Italy.; Università di Siena, Siena, Italy.
Faleri A; GSK, Siena, Italy.
Utrio Lanfaloni S; GSK, Siena, Italy.
Pansegrau W; GSK, Siena, Italy.
d'Alterio L; GSK, Siena, Italy.
Bartolini E; GSK, Siena, Italy.
Pinzuti I; GSK, Siena, Italy.
Sampieri K; GSK, Siena, Italy.
Giordano A; GSK, Siena, Italy.
Rappuoli R; GSK, Siena, Italy.
Pizza M; GSK, Siena, Italy.
Masignani V; GSK, Siena, Italy.
Norais N; GSK, Siena, Italy.
Maione D; GSK, Siena, Italy.
Merola M; GSK, Siena, Italy.; Università di Napoli Federico II, Naples, Italy.; Pokaż więcej
Źródło:: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0110724. Date of Electronic Publication: 2024 Jul 23.
Typ publikacji:: Journal Article
MeSH Terms:: Adhesins, Bacterial*/metabolism
Adhesins, Bacterial*/genetics
Bacterial Adhesion*
Antigens, CD*/metabolism
Antigens, CD*/genetics
Lectins*/metabolism
Lectins*/genetics
Lectins*/immunology
Antigens, Differentiation, Myelomonocytic*/metabolism
Antigens, Differentiation, Myelomonocytic*/genetics
Host-Pathogen Interactions*
Humans ; Animals ; Protein Binding ; Mice ; CHO Cells ; Cricetulus ; Neisseria meningitidis/genetics ; Neisseria meningitidis/metabolism ; Neisseria meningitidis/immunology ; Recombinant Proteins/metabolism ; Recombinant Proteins/genetics ; Sialic Acid Binding Immunoglobulin-like Lectins/metabolism ; Sialic Acid Binding Immunoglobulin-like Lectins/genetics ; Epithelial Cells/microbiology ; Epithelial Cells/metabolism ; Epithelial Cells/immunology ; Meningococcal Infections/microbiology ; Meningococcal Infections/immunology ; Receptors, Cell Surface/metabolism ; Receptors, Cell Surface/genetics ; Neisseria meningitidis, Serogroup B/genetics ; Neisseria meningitidis, Serogroup B/immunology ; Neisseria meningitidis, Serogroup B/metabolism

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Tytuł:: Anti-LAG-3 boosts CD8 T cell effector function.
Autorzy:: Kureshi CT; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA; Program in Immunology, Harvard Medical School, Boston, MA, USA.
Dougan M; Program in Immunology, Harvard Medical School, Boston, MA, USA; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Dougan SK; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA; Program in Immunology, Harvard Medical School, Boston, MA, USA. Electronic address: stephanie_.; Pokaż więcej
Źródło:: Cell [Cell] 2024 Aug 08; Vol. 187 (16), pp. 4144-4146.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Lymphocyte Activation Gene 3 Protein*
CD8-Positive T-Lymphocytes*/immunology
Antigens, CD*/metabolism
Antigens, CD*/immunology
Humans ; Animals ; Mice ; Melanoma/immunology ; Melanoma/drug therapy ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/metabolism ; Programmed Cell Death 1 Receptor/immunology ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use

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Tytuł:: Clinical Significance of TNFSF14/LIGHT and CD160 in Gastric Cancer and Peptic Ulcer Dyspepsia.
Autorzy:: Keykhosravi M; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Asgarian-Omran H; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Valadan R; Department of Immunology, Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Tehrani M; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Javadzadeh SM; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Taghiloo S; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Najafi A; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Fatehi Q; Babol University of Medical Science, Mazandaran, Babol, Iran.
Majd I; Ardebil University of Medical science, Ardebil, Iran.
Ajami A; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Molecular and Cell Biology Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.; Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.; Pokaż więcej
Źródło:: Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2024 Aug 01; Vol. 25 (8), pp. 2669-2677. Date of Electronic Publication: 2024 Aug 01.
Typ publikacji:: Journal Article
MeSH Terms:: Stomach Neoplasms*/pathology
Stomach Neoplasms*/metabolism
Stomach Neoplasms*/genetics
Tumor Necrosis Factor Ligand Superfamily Member 14*/metabolism
Tumor Necrosis Factor Ligand Superfamily Member 14*/genetics
Antigens, CD*/metabolism
Antigens, CD*/genetics
GPI-Linked Proteins*/genetics
GPI-Linked Proteins*/metabolism
Dyspepsia*/metabolism
Dyspepsia*/pathology
Dyspepsia*/genetics
Peptic Ulcer*/metabolism
Peptic Ulcer*/pathology
Peptic Ulcer*/genetics
Humans ; Male ; Female ; Middle Aged ; Case-Control Studies ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Prognosis ; Follow-Up Studies ; Aged ; Adult ; Receptors, Immunologic/metabolism ; Receptors, Immunologic/genetics ; RNA, Messenger/genetics ; Clinical Relevance

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Tytuł:: PD-1/LAG-3 co-signaling profiling uncovers CBL ubiquitin ligases as key immunotherapy targets.
Autorzy:: Chocarro L; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain. .
Blanco E; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.; Division of Gene Therapy and Regulation of Gene Expression, Cima Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Fernandez-Rubio L; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Garnica M; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Zuazo M; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Garcia MJ; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Bocanegra A; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Echaide M; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Johnston C; Crescendo Biologics Ltd., Meditrina Building, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Edwards CJ; Crescendo Biologics Ltd., Meditrina Building, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Legg J; Crescendo Biologics Ltd., Meditrina Building, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Pierce AJ; Crescendo Biologics Ltd., Meditrina Building, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Arasanz H; Medical Oncology Unit, Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.; Oncobiona Unit, Navarrabiomed, Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Fernandez-Hinojal G; Medical Oncology Unit, Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Vera R; Medical Oncology Unit, Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Ausin K; Proteomics Platform, Proteored-ISCIII, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Santamaria E; Proteomics Platform, Proteored-ISCIII, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Fernandez-Irigoyen J; Proteomics Platform, Proteored-ISCIII, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Kochan G; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain.
Escors D; OncoImmunology Unit, Navarrabiomed - Fundación Miguel Servet, Universidad Pública de Navarra (UPNA), Hospital Universitario de Navarra (HUN), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008, Pamplona, Spain. .; Pokaż więcej
Źródło:: EMBO molecular medicine [EMBO Mol Med] 2024 Aug; Vol. 16 (8), pp. 1791-1816. Date of Electronic Publication: 2024 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Lymphocyte Activation Gene 3 Protein*
Programmed Cell Death 1 Receptor*/metabolism
Programmed Cell Death 1 Receptor*/antagonists & inhibitors
Proto-Oncogene Proteins c-cbl*/metabolism
Proto-Oncogene Proteins c-cbl*/genetics
Immunotherapy*/methods
Signal Transduction*/drug effects
Antigens, CD*/metabolism
Antigens, CD*/genetics
Humans ; Animals ; Mice ; Neoplasms/therapy ; Neoplasms/drug therapy ; Neoplasms/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Cell Line, Tumor ; Immune Checkpoint Inhibitors/therapeutic use ; Immune Checkpoint Inhibitors/pharmacology

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Tytuł:: Expression of transferrin receptor/TFRC protein in bladder cancer cell T24 and its role in inducing iron death in bladder cancer.
Autorzy:: Qin J; Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China.
Li Z; Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China.
Su L; Department of Urology, Baidong Hospital, Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China.
Wen X; Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China.
Tang X; Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China.
Huang M; Department of Urology, Baidong Hospital, Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China. Electronic address: .
Wu J; Department of Urology, Baidong Hospital, Affiliated Hospital of Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Aug; Vol. 274 (Pt 1), pp. 133323. Date of Electronic Publication: 2024 Jun 20.
Typ publikacji:: Journal Article
MeSH Terms:: Endoplasmic Reticulum Chaperone BiP*
Gene Expression Regulation, Neoplastic*
Iron*/metabolism
Receptors, Transferrin*/genetics
Receptors, Transferrin*/metabolism
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/pathology
Urinary Bladder Neoplasms*/metabolism
Urinary Bladder Neoplasms*/mortality
Antigens, CD*/genetics
Antigens, CD*/metabolism
Humans ; Cell Line, Tumor ; Ferroptosis/genetics

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Tytuł:: circ0005027 Acting as a ceRNA Affects the Malignant Biological Behavior of Hypopharyngeal Squamous Cell Carcinoma by Modulating miR-548c-3p/CDH1 Axis.
Autorzy:: Yang X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Feng C; Department of Otolaryngology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650034, Yunnan, China.
Jiang D; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Xu X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Zhang Y; Department of Pathology and Pathophysiology, School of Basic Medical Science, Kunming Medical University, Kunming, 650500, Yunnan, China.
Wang J; Department of Otolaryngology, The Second People's Hospital of Yunnan Province, Kunming, 650021, Yunnan, China.
He X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China. .; Pokaż więcej
Źródło:: Biochemical genetics [Biochem Genet] 2024 Aug; Vol. 62 (4), pp. 2853-2868. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Hypopharyngeal Neoplasms*/genetics
Hypopharyngeal Neoplasms*/metabolism
Hypopharyngeal Neoplasms*/pathology
Antigens, CD*/genetics
Antigens, CD*/metabolism
Humans ; Gene Expression Regulation, Neoplastic ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology ; Cell Line, Tumor ; Cell Proliferation ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Female ; Apoptosis ; RNA, Competitive Endogenous

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Tytuł:: CD69 Vδ1γδ T cells are anti-tumor subpopulations in hepatocellular carcinoma.
Autorzy:: You H; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Wang Y; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Wang X; Department of Clinical Laboratory, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Zhu H; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Zhao Y; Department of Breast, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Qin P; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Liu X; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Zhang M; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Fu X; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Xu B; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Zhang Y; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Wang Z; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China.
Gao Q; Department of Immunotherapy, the Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, China. Electronic address: .; Pokaż więcej
Źródło:: Molecular immunology [Mol Immunol] 2024 Aug; Vol. 172, pp. 76-84. Date of Electronic Publication: 2024 Jun 24.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/immunology
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/immunology
Liver Neoplasms*/pathology
Antigens, Differentiation, T-Lymphocyte*/immunology
Lectins, C-Type*/immunology
Lectins, C-Type*/metabolism
Antigens, CD*/immunology
Antigens, CD*/metabolism
Receptors, Antigen, T-Cell, gamma-delta*/immunology
Receptors, Antigen, T-Cell, gamma-delta*/metabolism
Tumor Microenvironment*/immunology
Humans ; Male ; Female ; Middle Aged ; Lymphocytes, Tumor-Infiltrating/immunology ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; Adult

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Tytuł:: MD-1 downregulation is associated with reduced cell surface CD180 expression in CLL.
Autorzy:: Edwards K; School of Life Sciences, University of Westminster, London, UK. Electronic address: .
Manoussaka M; UCL Cancer Institute, University College London, London, UK.
Sayed U; School of Life Sciences, University of Westminster, London, UK.
Tsertsvadze T; Tbilisi State University, Tbilisi, GA, USA.
Deyn L; School of Life Sciences, University of Westminster, London, UK. Electronic address: .
Nathwani A; UCL Cancer Institute, University College London, London, UK. Electronic address: .
Gribben JG; Barts Cancer Institute, Queen Mary University, London, UK. Electronic address: .
Krysov S; Barts Cancer Institute, Queen Mary University, London, UK. Electronic address: .
Volpi EV; School of Life Sciences, University of Westminster, London, UK. Electronic address: .
Lydyard PM; School of Life Sciences, University of Westminster, London, UK; The University of Georgia, Tbilisi, GA, USA.
Porakishvili N; School of Life Sciences, University of Westminster, London, UK. Electronic address: .; Pokaż więcej
Źródło:: Leukemia research [Leuk Res] 2024 Aug; Vol. 143, pp. 107540. Date of Electronic Publication: 2024 Jun 11.
Typ publikacji:: Journal Article
MeSH Terms:: Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
Leukemia, Lymphocytic, Chronic, B-Cell*/pathology
Leukemia, Lymphocytic, Chronic, B-Cell*/metabolism
Leukemia, Lymphocytic, Chronic, B-Cell*/immunology
Down-Regulation*
Antigens, CD*/metabolism
Antigens, CD*/genetics
Humans ; Cell Membrane/metabolism ; Gene Expression Regulation, Leukemic

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Tytuł:: Impact of LAG-3/FGL1 pathway on immune evasive contexture and clinical outcomes in advanced urothelial carcinoma.
Autorzy:: Yoshida T; Department of Urology and Andrology, Kansai Medical University, Osaka, Japan .; Graduate School of Engineering, Tottori University, Tottori, Japan.; Department of Urology, Osaka Saiseikai-Noe Hospital, Osaka, Japan.; Corporate Sponsored Research Programs for Multicellular Interactions in Cancer, Kansai Medical University, Osaka, Japan.
Nakamoto T; Department of Urology and Andrology, Kansai Medical University, Osaka, Japan.; Department of Pathology, Kansai Medical University, Osaka, Japan.
Atsumi N; Corporate Sponsored Research Programs for Multicellular Interactions in Cancer, Kansai Medical University, Osaka, Japan.; Department of Pathology, Kansai Medical University, Osaka, Japan.
Ohe C; Department of Urology and Andrology, Kansai Medical University, Osaka, Japan.; Department of Pathology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Sano T; Department of Urology and Andrology, Kansai Medical University, Osaka, Japan.
Yasukochi Y; Department of Genome Analysis, Institute of Biomedical Science, Kansai Medical University, Osaka, Japan.
Tsuta K; Corporate Sponsored Research Programs for Multicellular Interactions in Cancer, Kansai Medical University, Osaka, Japan.; Department of Pathology, Kansai Medical University, Osaka, Japan.
Kinoshita H; Department of Urology and Andrology, Kansai Medical University, Osaka, Japan.; Pokaż więcej
Źródło:: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Jul 23; Vol. 12 (7). Date of Electronic Publication: 2024 Jul 23.
Typ publikacji:: Journal Article
MeSH Terms:: Lymphocyte Activation Gene 3 Protein*
Antigens, CD*/metabolism
Antigens, CD*/genetics
Humans ; Male ; Female ; Aged ; Middle Aged ; Urologic Neoplasms/drug therapy ; Urologic Neoplasms/immunology ; Urologic Neoplasms/genetics ; Urologic Neoplasms/pathology ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/immunology ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/pathology

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Tytuł:: Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease.
Autorzy:: Saevarsdottir S; deCODE genetics/Amgen, Inc., Reykjavik, Iceland. .; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. .; Department of Medicine, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland. .
Bjarnadottir K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Markusson T; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Berglund J; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Olafsdottir TA; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Halldorsson GH; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Rutsdottir G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Gunnarsdottir K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Arnthorsson AO; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Lund SH; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Stefansdottir L; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Gudmundsson J; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Johannesson AJ; Department of Medicine, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Sturluson A; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Oddsson A; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Halldorsson B; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Ludviksson BR; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Ferkingstad E; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Ivarsdottir EV; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Sveinbjornsson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Grondal G; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Medicine, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Masson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Eldjarn GH; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Thorisson GA; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Kristjansdottir K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Knowlton KU; Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, UT, USA.; School of Medicine, University of Utah, Salt Lake City, UT, USA.
Moore KHS; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Gudjonsson SA; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Rognvaldsson S; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Knight S; Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, UT, USA.
Nadauld LD; Precision Genomics, Intermountain Healthcare, Saint George, UT, USA.
Holm H; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Magnusson OT; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Sulem P; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Gudbjartsson DF; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Rafnar T; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Thorleifsson G; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Melsted P; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Norddahl GL; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.
Jonsdottir I; deCODE genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Immunology, Landspitali, the National University Hospital of Iceland, Reykjavik, Iceland.
Stefansson K; deCODE genetics/Amgen, Inc., Reykjavik, Iceland. .; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. .; Pokaż więcej
Źródło:: Nature communications [Nat Commun] 2024 Jul 09; Vol. 15 (1), pp. 5748. Date of Electronic Publication: 2024 Jul 09.
Typ publikacji:: Journal Article
MeSH Terms:: Lymphocyte Activation Gene 3 Protein*
Genetic Predisposition to Disease*
Codon, Initiator*/genetics
Antigens, CD*/genetics
Antigens, CD*/metabolism
Humans ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 1/immunology ; Female ; Polymorphism, Single Nucleotide ; Vitiligo/genetics ; Male ; Genome-Wide Association Study ; Thyroiditis, Autoimmune/genetics ; 5' Untranslated Regions/genetics ; Case-Control Studies ; Iceland ; Adult

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Tytuł:: Soluble CD72, is a T-cell activator probably via binding to CD6 in homeostasis and autoimmunity.
Autorzy:: Eiza N; The Proteomic Unit, Bnai Zion Medical Center, Haifa, Israel.; The Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Sabag A; The Proteomic Unit, Bnai Zion Medical Center, Haifa, Israel.
Kessler O; The Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Toubi E; The Proteomic Unit, Bnai Zion Medical Center, Haifa, Israel.
Vadasz Z; The Proteomic Unit, Bnai Zion Medical Center, Haifa, Israel.; The Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.; Pokaż więcej
Źródło:: Frontiers in immunology [Front Immunol] 2024 Jul 04; Vol. 15, pp. 1367120. Date of Electronic Publication: 2024 Jul 04 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Lymphocyte Activation*/immunology
Autoimmunity*
CD4-Positive T-Lymphocytes*/immunology
CD4-Positive T-Lymphocytes*/metabolism
Antigens, CD*/metabolism
Antigens, CD*/immunology
Homeostasis*/immunology
Humans ; Antigens, Differentiation, T-Lymphocyte/metabolism ; Antigens, Differentiation, T-Lymphocyte/immunology ; Signal Transduction ; Cell Proliferation ; Protein Binding ; Cytokines/metabolism ; Antigens, Differentiation, B-Lymphocyte

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Tytuł:: Nanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus.
Autorzy:: Yang H; MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Sun M; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Qiu H; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Xu H; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Deng Z; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Gu H; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Wang N; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China.
Du L; MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Shi F; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.; Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Zhou J; MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.
He F; MOA Key Laboratory of Animal Virology, Zhejiang University Center for Veterinary Sciences, Hangzhou, China. .; Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China. .; ZJU-Xinchang Joint Innovation Centre (TianMu Laboratory), Gaochuang Hi-Tech Park, Xinchang, Zhejiang, P.R. China. .; Pokaż więcej
Źródło:: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jul 02; Vol. 22 (1), pp. 388. Date of Electronic Publication: 2024 Jul 02.
Typ publikacji:: Journal Article
MeSH Terms:: Porcine respiratory and reproductive syndrome virus*/immunology
Porcine respiratory and reproductive syndrome virus*/drug effects
Single-Domain Antibodies*/immunology
Single-Domain Antibodies*/pharmacology
Single-Domain Antibodies*/chemistry
Antigens, Differentiation, Myelomonocytic*/immunology
Antigens, Differentiation, Myelomonocytic*/metabolism
Receptors, Cell Surface*/immunology
Antigens, CD*/immunology
Antigens, CD*/metabolism
Antibodies, Neutralizing*/immunology
Peptides*/chemistry
Peptides*/pharmacology
Peptides*/immunology
Animals ; Swine ; Porcine Reproductive and Respiratory Syndrome/immunology ; Porcine Reproductive and Respiratory Syndrome/prevention & control ; Mice ; Virus Replication/drug effects ; Cell Line

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