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Wyszukujesz frazę ""Antigens, CD"" wg kryterium: Temat


Tytuł :
Erythropoietin maintains VE-cadherin expression and barrier function in experimental diabetic retinopathy via inhibiting VEGF/VEGFR2/Src signaling pathway.
Autorzy :
Liu D; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Children's Hospital of Soochow University, Suzhou, China.
Zhang C; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xie H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Yang Q; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Li W; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, United States.
Tian H; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Lu L; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu JY; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China.
Xu G; Department of Ophthalmology, the Second Affiliated Hospital of Soochow University, Suzhou, China.
Liu K; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.
Sun X; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China.
Xu GT; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China. Electronic address: .
Zhang J; Department of Ophthalmology of Shanghai Tenth People's Hospital, Tongji Eye Institute, Department of Regenerative Medicine, and Department of Pharmacology, Tongji University School of Medicine, Shanghai, China; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118273. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*biosynthesis
Blood-Retinal Barrier/*metabolism
Cadherins/*biosynthesis
Diabetic Retinopathy/*metabolism
Erythropoietin/*pharmacology
Vascular Endothelial Growth Factor A/*metabolism
Vascular Endothelial Growth Factor Receptor-2/*metabolism
src-Family Kinases/*metabolism
Animals ; Antigens, CD/genetics ; Antigens, CD/metabolism ; Blood-Retinal Barrier/drug effects ; Blood-Retinal Barrier/pathology ; Cadherins/genetics ; Cadherins/metabolism ; Capillary Permeability/drug effects ; Diabetes Mellitus, Experimental/metabolism ; Diabetic Retinopathy/pathology ; Down-Regulation ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Male ; Rats ; Rats, Sprague-Dawley ; Recombinant Proteins/pharmacology ; Retinal Vessels/drug effects ; Retinal Vessels/metabolism ; Retinal Vessels/pathology
Czasopismo naukowe
Tytuł :
LncRNA UCA1 maintains the low-tumorigenic and nonmetastatic status by stabilizing E-cadherin in primary prostate cancer cells.
Autorzy :
Zhao X; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang Y; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
He J; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Deng R; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huang X; Faculty of Health of Sciences, Institute of Translational Medicine, University of Macau, Macau SAR, China.
Guo Y; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li L; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xie R; Faculty of Health of Sciences, Institute of Translational Medicine, University of Macau, Macau SAR, China.
Yu J; Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Basic Clinical Research Center, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.
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Źródło :
Molecular carcinogenesis [Mol Carcinog] 2020 Oct; Vol. 59 (10), pp. 1174-1187. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Antigens, CD/*metabolism
Biomarkers, Tumor/*metabolism
Cadherins/*metabolism
MicroRNAs/*genetics
Prostatic Neoplasms/*pathology
RNA, Long Noncoding/*genetics
Animals ; Antigens, CD/genetics ; Apoptosis ; Biomarkers, Tumor/genetics ; Cadherins/genetics ; Cell Proliferation ; Humans ; Male ; Mice ; Mice, SCID ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Increased Serum Levels of sCD14 and sCD163 Indicate a Preponderant Role for Monocytes in COVID-19 Immunopathology.
Autorzy :
Gómez-Rial J; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Laboratorio de Inmunologìa, Servicio de Análisis Clìnicos, Hospital Clìnico Universitario Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.
Currás-Tuala MJ; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.
Rivero-Calle I; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Translational Pediatrics and Infectious Diseases Section, Department of Pediatrics, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Gómez-Carballa A; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Unidade de Xenética, Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clìnico Universitario de Santiago, Servizo Galego de Saúde, Galicia, Spain.
Cebey-López M; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.
Rodríguez-Tenreiro C; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.
Dacosta-Urbieta A; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Translational Pediatrics and Infectious Diseases Section, Department of Pediatrics, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Rivero-Velasco C; Intensive Medicine Department, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Rodríguez-Núñez N; Pneumology Department, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Trastoy-Pena R; Microbiology Department, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Rodríguez-García J; Clinical Biochemistry Laboratory, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
Salas A; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Unidade de Xenética, Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clìnico Universitario de Santiago, Servizo Galego de Saúde, Galicia, Spain.
Martinón-Torres F; Grupo de Investigación en Genética, Vacunas, Infecciones y Pediatría, Instituto de Investigación Sanitaria de Santiago, Hospital Clinico Universitario and Universidade de Santiago de Compostela, Servizo Galego de Saúde, Galicia, Spain.; Translational Pediatrics and Infectious Diseases Section, Department of Pediatrics, Hospital Clìnico Universitario de Santiago de Compostela, Galicia, Spain.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Sep 23; Vol. 11, pp. 560381. Date of Electronic Publication: 2020 Sep 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD*/blood
Antigens, CD*/immunology
Antigens, Differentiation, Myelomonocytic*/blood
Antigens, Differentiation, Myelomonocytic*/immunology
Betacoronavirus*/immunology
Betacoronavirus*/metabolism
Coronavirus Infections*/blood
Coronavirus Infections*/drug therapy
Coronavirus Infections*/immunology
Coronavirus Infections*/pathology
Lipopolysaccharide Receptors*/blood
Lipopolysaccharide Receptors*/immunology
Pandemics*
Pneumonia, Viral*/blood
Pneumonia, Viral*/drug therapy
Pneumonia, Viral*/immunology
Pneumonia, Viral*/pathology
Receptors, Cell Surface*/blood
Receptors, Cell Surface*/immunology
Adrenal Cortex Hormones/administration & dosage ; Adult ; Aged ; Antibodies, Monoclonal, Humanized/administration & dosage ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Intensive Care Units ; Interleukin-6/blood ; Interleukin-6/immunology ; Macrophage Activation ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Middle Aged ; Monocytes/immunology ; Monocytes/pathology ; Patient Admission ; Time Factors
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Single-cell landscape of immunological responses in patients with COVID-19.
Autorzy :
Zhang JY; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Wang XM; Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China.
Xing X; Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing, China.
Xu Z; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Zhang C; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Song JW; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Fan X; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Xia P; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Fu JL; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Wang SY; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Xu RN; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Dai XP; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Shi L; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Huang L; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Jiang TJ; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Shi M; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
Zhang Y; Guangzhou Women and Children's Medical Center, State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, Guangzhou, Guangdong, China.
Zumla A; Department of Infection, Division of Infection and Immunity, University College London, London, UK.; National Institute for Health Research Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK.
Maeurer M; Immunotherapy Programme, Champalimaud Centre for the Unknown, Lisbon, Portugal.; I Med Clinic, University of Mainz, Mainz, Germany.
Bai F; Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing, China. .
Wang FS; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China. .
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Źródło :
Nature immunology [Nat Immunol] 2020 Sep; Vol. 21 (9), pp. 1107-1118. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
Antigens, Differentiation, T-Lymphocyte/*metabolism
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Interferon Type I/*metabolism
Pneumonia, Viral/*immunology
Receptors, Immunologic/*metabolism
Adolescent ; Adult ; Aged ; Antigens, CD/genetics ; Antigens, CD/immunology ; Antigens, Differentiation, T-Lymphocyte/genetics ; Antigens, Differentiation, T-Lymphocyte/immunology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cohort Studies ; Coronavirus Infections/blood ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Female ; GPI-Linked Proteins/genetics ; GPI-Linked Proteins/immunology ; GPI-Linked Proteins/metabolism ; Humans ; Interferon Type I/genetics ; Interferon Type I/immunology ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; RNA-Seq ; Receptors, Immunologic/genetics ; Receptors, Immunologic/immunology ; Severity of Illness Index ; Single-Cell Analysis
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
[Butyrophilin 3A1 (BTN3A1) enhances activation and proliferation of human peripheral blood Vγ9Vδ2 T cells induced by MTB-HAg].
Autorzy :
Tang J; Department of Immunology, Bengbu Medical College, Anhui Key Laboratory of Infection and Immunity, Science Research Centre, Bengbu Medical College, Bengbu 233000, China. *Corresponding authors, E-mail: .
Sun J; Science Research Centre, Bengbu Medical College, Bengbu 233000, China.
Zha C; Science Research Centre, Bengbu Medical College, Bengbu 233000, China.
Chang J; Science Research Centre, Bengbu Medical College, Bengbu 233000, China.
Hu K; Science Research Centre, Bengbu Medical College, Bengbu 233000, China.
Fang Q; Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu 233000, China.
Chen Y; Department of Immunology, Bengbu Medical College, Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu 233000, China.
Chen J; Department of Immunology, Bengbu Medical College, Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu 233000, China.
Li B; Department of Immunology, Bengbu Medical College, Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu 233000, China. *Corresponding authors, E-mail: .
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Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2020 Aug; Vol. 36 (8), pp. 680-686.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Bacterial*/immunology
Antigens, CD*/genetics
Antigens, CD*/metabolism
Butyrophilins*/genetics
Butyrophilins*/metabolism
Lymphocyte Activation*/genetics
T-Lymphocytes*/cytology
T-Lymphocytes*/immunology
Cell Proliferation/genetics ; Humans ; Receptors, Antigen, T-Cell, gamma-delta/metabolism
Czasopismo naukowe
Tytuł :
BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells.
Autorzy :
Payne KK; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Mine JA; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Biswas S; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Chaurio RA; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Perales-Puchalt A; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Anadon CM; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Costich TL; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Harro CM; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.; Department of Cell Biology, Microbiology, and Molecular Biology and Cancer Biology PhD Program, University of South Florida, Tampa, FL 33620, USA.
Walrath J; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Ming Q; Drug Discovery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Tcyganov E; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Buras AL; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Rigolizzo KE; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Mandal G; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Lajoie J; Compass Therapeutics, Cambridge, MA 02142, USA.
Ophir M; Compass Therapeutics, Cambridge, MA 02142, USA.
Tchou J; Division of Endocrine and Oncologic Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA 19104-1693, USA.
Marchion D; Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Luca VC; Drug Discovery, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Bobrowicz P; Compass Therapeutics, Cambridge, MA 02142, USA.
McLaughlin B; Compass Therapeutics, Cambridge, MA 02142, USA.
Eskiocak U; Compass Therapeutics, Cambridge, MA 02142, USA.
Schmidt M; Compass Therapeutics, Cambridge, MA 02142, USA.
Cubillos-Ruiz JR; Department of Obstetrics and Gynecology, Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
Rodriguez PC; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Gabrilovich DI; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Conejo-Garcia JR; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. .; Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2020 Aug 21; Vol. 369 (6506), pp. 942-949.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*immunology
Butyrophilins/*antagonists & inhibitors
Butyrophilins/*immunology
Intraepithelial Lymphocytes/*immunology
Ovarian Neoplasms/*immunology
Ovarian Neoplasms/*therapy
Animals ; Antibodies, Monoclonal/therapeutic use ; Antigens, CD/genetics ; Butyrophilins/genetics ; Female ; Humans ; Immunotherapy/methods ; Mice ; Mice, Transgenic ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Characterization of CD103 tissue-resident T cells in esophageal squamous cell carcinoma: may be tumor reactive and resurrected by anti-PD-1 blockade.
Autorzy :
Han L; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.; Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Gao QL; Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Zhou XM; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Shi C; Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Chen GY; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
Song YP; Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Yao YJ; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Zhao YM; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Wen XY; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Liu SL; Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Qi YM; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Gao YF; School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China. .; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Aug; Vol. 69 (8), pp. 1493-1504. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Esophageal Neoplasms/*immunology
Esophageal Neoplasms/*metabolism
Integrin alpha Chains/*metabolism
Lymphocytes, Tumor-Infiltrating/*immunology
Programmed Cell Death 1 Receptor/*antagonists & inhibitors
Tumor Microenvironment/*immunology
4-Nitroquinoline-1-oxide/toxicity ; Adult ; Aged ; Animals ; Antibodies, Monoclonal/pharmacology ; Antigens, CD/immunology ; Biomarkers, Tumor ; Carcinogens/toxicity ; Cohort Studies ; Esophageal Neoplasms/chemically induced ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma/chemically induced ; Esophageal Squamous Cell Carcinoma/immunology ; Esophageal Squamous Cell Carcinoma/metabolism ; Esophageal Squamous Cell Carcinoma/pathology ; Female ; Follow-Up Studies ; Humans ; Integrin alpha Chains/immunology ; Male ; Mice, Inbred C57BL ; Middle Aged ; Prognosis ; Programmed Cell Death 1 Receptor/immunology ; Survival Rate ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer.
Autorzy :
Rajabinejad M; Student Research Committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Asadi G; Student Research Committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Ranjbar S; Student Research Committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Afshar Hezarkhani L; Department of Neurology, Farabi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Salari F; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Gorgin Karaji A; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Rezaiemanesh A; Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: .
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Źródło :
Gene [Gene] 2020 Jul 01; Vol. 746, pp. 144637. Date of Electronic Publication: 2020 Mar 31.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Autoimmunity*
Antigens, CD/*metabolism
Hypersensitivity/*metabolism
Neoplasm Proteins/*metabolism
Neoplasms/*metabolism
Semaphorins/*metabolism
Antigens, CD/genetics ; Humans ; Hypersensitivity/genetics ; Hypersensitivity/pathology ; Neoplasm Proteins/genetics ; Neoplasms/genetics ; Neoplasms/pathology ; Semaphorins/genetics
Czasopismo naukowe
Tytuł :
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
Autorzy :
Xiong X; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.
Menting JG; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.
Disotuar MM; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.
Smith NA; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.
Delaine CA; Discipline of Medical Biochemistry, Flinders University, Bedford Park, South Australia, Australia.
Ghabash G; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.
Agrawal R; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Wang X; Department of Pathology, University of Utah, Salt Lake City, UT, USA.
He X; Department of Pathology, University of Utah, Salt Lake City, UT, USA.
Fisher SJ; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
MacRaild CA; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Norton RS; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Gajewiak J; Department of Biology, University of Utah, Salt Lake City, UT, USA.
Forbes BE; Discipline of Medical Biochemistry, Flinders University, Bedford Park, South Australia, Australia.
Smith BJ; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia.
Safavi-Hemami H; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Olivera B; Department of Biology, University of Utah, Salt Lake City, UT, USA.
Lawrence MC; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. .; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia. .
Chou DH; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2020 Jul; Vol. 27 (7), pp. 615-624. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*chemistry
Insulin/*chemistry
Mollusk Venoms/*chemistry
Mollusk Venoms/*metabolism
Receptor, Insulin/*chemistry
Amino Acid Substitution ; Animals ; Antigens, CD/metabolism ; Binding Sites ; Crystallography, X-Ray ; Insulin/analogs & derivatives ; Insulin/metabolism ; Insulin/pharmacology ; Mice, Inbred C57BL ; Models, Molecular ; Molecular Dynamics Simulation ; Mollusk Venoms/genetics ; Mollusk Venoms/pharmacology ; Peptides/chemistry ; Peptides/genetics ; Peptides/metabolism ; Protein Conformation ; Rats, Sprague-Dawley ; Receptor, Insulin/metabolism ; Structure-Activity Relationship ; Tyrosine
Czasopismo naukowe
Tytuł :
Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.
Autorzy :
Umviligihozo G; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Cobarrubias KD; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Chandrarathna S; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Jin SW; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.
Reddy N; University of KwaZulu-Natal, Durban, South Africa.; Africa Health Research Institute, Durban, South Africa.
Byakwaga H; Mbarara University of Science and Technology, Mbarara, Uganda.; University of California, San Francisco, California, USA.
Muzoora C; Mbarara University of Science and Technology, Mbarara, Uganda.
Bwana MB; Mbarara University of Science and Technology, Mbarara, Uganda.
Lee GQ; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Hunt PW; University of California, San Francisco, California, USA.
Martin JN; University of California, San Francisco, California, USA.
Brumme CJ; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.; University of British Columbia, Vancouver, British Columbia, Canada.
Bangsberg DR; Oregon Health and Science University-Portland State University School of Public Health, Portland, Oregon, USA.
Karita E; Rwanda Zambia HIV Research Group-Projet San Francisco, Kigali, Rwanda.
Allen S; Rwanda Zambia HIV Research Group-Projet San Francisco, Kigali, Rwanda.; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA.; Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Hunter E; Rwanda Zambia HIV Research Group-Projet San Francisco, Kigali, Rwanda.; Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Ndung'u T; University of KwaZulu-Natal, Durban, South Africa.; Africa Health Research Institute, Durban, South Africa.; Max Planck Institute for Infection Biology, Berlin, Germany.; Division of Infection and Immunity, University College London, London, United Kingdom.
Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Brockman MA; Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada .; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
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Źródło :
Journal of virology [J Virol] 2020 Jul 01; Vol. 94 (14). Date of Electronic Publication: 2020 Jul 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Down-Regulation*
HIV Infections*
Antigens, CD/*biosynthesis
CD4 Antigens/*biosynthesis
HIV-1/*metabolism
Human Immunodeficiency Virus Proteins/*metabolism
Viral Regulatory and Accessory Proteins/*metabolism
Antigens, CD/genetics ; CD4 Antigens/genetics ; Cell Line, Transformed ; Chronic Disease ; GPI-Linked Proteins/biosynthesis ; GPI-Linked Proteins/genetics ; HIV-1/genetics ; Human Immunodeficiency Virus Proteins/genetics ; Humans ; Viral Regulatory and Accessory Proteins/genetics
Czasopismo naukowe
Tytuł :
Human CD200 Suppresses the HL-60 Mediated Xenocytotoxicity.
Autorzy :
Eguchi H; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Maeda A; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. Electronic address: .
Matsuura R; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Shabri AM; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Lo PC; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Kodama T; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Noguchi Y; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Yoneyama T; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Toyama C; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Tazuke Y; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Okuyama H; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Miyagawa S; Department of Pediatric Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
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Źródło :
Transplantation proceedings [Transplant Proc] 2020 Jul - Aug; Vol. 52 (6), pp. 1910-1912. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells*/immunology
Antigens, CD/*immunology
Heterografts/*immunology
Neutrophils/*immunology
Animals ; Antigens, CD/genetics ; Cell Line ; Cytotoxicity, Immunologic/immunology ; Humans ; Swine ; Transfection
Czasopismo naukowe
Tytuł :
Radiation-induced H3K9 tri-methylation in E-cadherin promoter during lung EMT: in vitro and in vivo approaches using vanillin.
Autorzy :
Sunnaghatta Nagaraja S; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
Raviraj R; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
Selvakumar I; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
Dharmalingam D; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
Ramadas N; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
Chellappan DR; Central Animal Facility, SASTRA Deemed University, Thanjavur, India.
Ponnachipudhur Chinnaswamy P; Central Animal Facility, SASTRA Deemed University, Thanjavur, India.
Nagarajan D; School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, India.
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Źródło :
Free radical research [Free Radic Res] 2020 Jul; Vol. 54 (7), pp. 540-555. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*metabolism
Benzaldehydes/*metabolism
Cadherins/*metabolism
Histones/*metabolism
Lung/*radiation effects
A549 Cells ; Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Epithelial-Mesenchymal Transition ; Female ; Humans ; Lung/metabolism ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lung Neoplasms/radiotherapy ; Methylation/radiation effects ; Oxidative Stress/radiation effects ; Promoter Regions, Genetic ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Food antigens and Transglutaminase 2 in IgA nephropathy: Molecular links between gut and kidney.
Autorzy :
Abbad L; INSERM UMR1149, Center of Research on Inflammation CRI, CNRS ERL8252, Paris, France; Inflamex Laboratory of Excellence, Paris Diderot University, Sorbonne Paris City, Paris, France.
Monteiro RC; INSERM UMR1149, Center of Research on Inflammation CRI, CNRS ERL8252, Paris, France; Inflamex Laboratory of Excellence, Paris Diderot University, Sorbonne Paris City, Paris, France; Immunology Department, AP-HP, DHU Fire, Paris, France.
Berthelot L; Centre de Recherche en Transplantation et Immunologie, Nantes, UMR1064, INSERM, Université de Nantes, France; Institut de Transplantation Urologie Néphrologie (ITUN), CHU de Nantes, Nantes, France; LabEx IGO, 'Immunotherapy, Graft, Oncology', Nantes, France. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 May; Vol. 121, pp. 1-6. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antigens, CD/*metabolism
GTP-Binding Proteins/*metabolism
Gliadin/*immunology
Glomerulonephritis, IGA/*immunology
Immunoglobulin A/*metabolism
Receptors, Transferrin/*metabolism
Transglutaminases/*metabolism
Animals ; Antigens, CD/genetics ; Antigens, CD/immunology ; Celiac Disease/immunology ; Celiac Disease/pathology ; Disease Models, Animal ; GTP-Binding Proteins/genetics ; GTP-Binding Proteins/immunology ; Gliadin/metabolism ; Humans ; Immunoglobulin A/immunology ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Mesangial Cells/immunology ; Mesangial Cells/pathology ; Mice ; Mice, Transgenic ; Receptors, Fc/genetics ; Receptors, Fc/immunology ; Receptors, Fc/metabolism ; Receptors, Transferrin/immunology ; Transglutaminases/genetics ; Transglutaminases/immunology ; Up-Regulation/immunology
Czasopismo naukowe
Tytuł :
T RM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection.
Autorzy :
Reilly EC; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
Lambert Emo K; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
Buckley PM; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
Reilly NS; Department of Physics and Astronomy, University of Rochester Medical Center, Rochester, NY 14642.
Smith I; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
Chaves FA; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
Yang H; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642.
Oakes PW; Department of Physics and Astronomy, University of Rochester Medical Center, Rochester, NY 14642.; Department of Biology, University of Rochester Medical Center, Rochester, NY 14642.
Topham DJ; Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, NY 14642; .; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 02; Vol. 117 (22), pp. 12306-12314. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antigens, CD/*immunology
Influenza A Virus, H3N2 Subtype/*physiology
Influenza, Human/*immunology
Integrin alpha Chains/*immunology
Integrin alpha1/*metabolism
Animals ; Antigens, CD/genetics ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; Cell Adhesion ; Cell Movement ; Humans ; Immunologic Memory ; Influenza A Virus, H3N2 Subtype/genetics ; Influenza, Human/genetics ; Influenza, Human/physiopathology ; Influenza, Human/virology ; Integrin alpha Chains/genetics ; Integrin alpha1/genetics ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Insufficient CD100 shedding contributes to suppression of CD8 T-cell activity in non-small cell lung cancer.
Autorzy :
Wang HM; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang XH; Department of Respiratory Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Ye LQ; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang K; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yang NN; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Geng S; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chen J; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhao SX; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yang KL; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fan FF; Department of Respiratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
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Źródło :
Immunology [Immunology] 2020 Jun; Vol. 160 (2), pp. 209-219. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, CD/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Carcinoma, Non-Small-Cell Lung/*immunology
Lung Neoplasms/*immunology
Matrix Metalloproteinase 14/*metabolism
Semaphorins/*metabolism
Adult ; Aged ; Antigens, CD/blood ; Bronchoalveolar Lavage Fluid/chemistry ; CD8-Positive T-Lymphocytes/metabolism ; Carcinoma, Non-Small-Cell Lung/blood ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Membrane/metabolism ; Coculture Techniques ; Female ; Humans ; Lung/pathology ; Lung Neoplasms/blood ; Lung Neoplasms/pathology ; Lymphocyte Activation ; Male ; Matrix Metalloproteinase 14/blood ; Middle Aged ; Primary Cell Culture ; Recombinant Proteins/metabolism ; Semaphorins/blood ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; Tumor Escape ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Compensatory increase of VE-cadherin expression through ETS1 regulates endothelial barrier function in response to TNFα.
Autorzy :
Colás-Algora N; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.
García-Weber D; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain. .; INSERM, U1016, Institut Cochin, Paris, France. .
Cacho-Navas C; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.
Barroso S; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.
Caballero A; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.; Departamento de Biología Molecular, Universidad Autónoma de Madrid, 28049, Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, 28006, Madrid, Spain.
Ribas C; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.; Departamento de Biología Molecular, Universidad Autónoma de Madrid, 28049, Madrid, Spain.; Instituto de Investigación Sanitaria La Princesa, 28006, Madrid, Spain.; CIBER de Enfermedades Cardiovasculares, ISCIII (CIBERCV), 28029, Madrid, Spain.
Correas I; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain.; Departamento de Biología Molecular, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Millán J; Centro de Biología Molecular 'Severo Ochoa' (CSIC-UAM), 28049, Madrid, Spain. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Jun; Vol. 77 (11), pp. 2125-2140. Date of Electronic Publication: 2019 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*metabolism
Cadherins/*metabolism
Endothelial Cells/*metabolism
Proto-Oncogene Protein c-ets-1/*metabolism
Tumor Necrosis Factor-alpha/*metabolism
Adherens Junctions/genetics ; Adherens Junctions/metabolism ; Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Capillary Permeability ; Endothelial Cells/cytology ; Gene Silencing ; Human Umbilical Vein Endothelial Cells ; Humans ; Inflammation/genetics ; Inflammation/metabolism ; Mice ; Proteolysis ; Proto-Oncogene Protein c-ets-1/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Regulation of CD71 erythroid progenitor cells by CD45.
Autorzy :
Shim YA; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Campbell T; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Weliwitigoda A; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Dosanjh M; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Johnson P; Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada. Electronic address: .
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Źródło :
Experimental hematology [Exp Hematol] 2020 Jun; Vol. 86, pp. 53-66.e1. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythropoiesis*
Hematopoiesis, Extramedullary*
Antigens, CD/*metabolism
Erythroid Precursor Cells/*metabolism
Leukocyte Common Antigens/*metabolism
Receptors, Transferrin/*metabolism
Animals ; Antigens, CD/genetics ; Erythroid Precursor Cells/cytology ; Leukocyte Common Antigens/genetics ; Mice ; Mice, Knockout ; Receptors, Transferrin/genetics ; Spleen/cytology ; Spleen/metabolism
Czasopismo naukowe
Tytuł :
CD160 expression on CD8 T cells is associated with active effector responses but limited activation potential in pancreatic cancer.
Autorzy :
Liu S; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, 71 Xinmin Avenue, Changchun, 130021, Jilin, China.
Zhang W; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, 71 Xinmin Avenue, Changchun, 130021, Jilin, China.
Liu K; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, 71 Xinmin Avenue, Changchun, 130021, Jilin, China.
Wang Y; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, 71 Xinmin Avenue, Changchun, 130021, Jilin, China. .
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 May; Vol. 69 (5), pp. 789-797. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*metabolism
CD8-Positive T-Lymphocytes/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
Pancreatic Neoplasms/*immunology
Receptors, Immunologic/*metabolism
T-Lymphocytes, Cytotoxic/*immunology
Adult ; Aged ; Antigens, CD/immunology ; Biopsy ; CD8-Positive T-Lymphocytes/metabolism ; Female ; GPI-Linked Proteins/immunology ; GPI-Linked Proteins/metabolism ; Humans ; Lymphocyte Activation ; Lymphocytes, Tumor-Infiltrating/metabolism ; Male ; Middle Aged ; Pancreas/cytology ; Pancreas/immunology ; Pancreas/pathology ; Pancreas/surgery ; Pancreatectomy ; Pancreatic Neoplasms/blood ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/surgery ; Receptors, Immunologic/immunology ; Survival Analysis ; T-Lymphocytes, Cytotoxic/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
Histologic transformation of t(11;18)-positive MALT lymphoma presented with aberrant T-cell marker expression.
Autorzy :
Tamura N; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Maeda H; Department of Diagnostic Pathology, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Nishikori M; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. .
Fujita H; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Hishizawa M; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Haga H; Department of Diagnostic Pathology, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Takaori-Kondo A; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
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Źródło :
International journal of hematology [Int J Hematol] 2020 May; Vol. 111 (5), pp. 724-732. Date of Electronic Publication: 2020 Jan 01.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Antigens, CD*
Translocation, Genetic*
Cell Transformation, Neoplastic/*genetics
Chromosomes, Human, Pair 11/*genetics
Lymphoma, B-Cell, Marginal Zone/*genetics
Lymphoma, B-Cell, Marginal Zone/*pathology
Humans ; Lymphoma, B-Cell, Marginal Zone/immunology ; T-Lymphocytes/immunology ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication.
Autorzy :
Mehta KJ; Centre for Education, Faculty of Life Sciences and Medicine, King's College London, London, UK. .; School of Life Sciences, University of Westminster, London, UK. .
Busbridge M; Department of Clinical Biochemistry, Northwest London Pathology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Patel VB; School of Life Sciences, University of Westminster, London, UK.
Farnaud SJ; Centre for Sport, Exercise and Life Sciences, Faculty of Health & Life Sciences, Coventry University, Coventry, UK.
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2020 May; Vol. 468 (1-2), pp. 121-128. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, CD/*metabolism
Hepatocytes/*metabolism
Hepcidins/*metabolism
Iron/*metabolism
Receptors, Transferrin/*metabolism
Antigens, CD/genetics ; Gene Expression/genetics ; Hep G2 Cells ; Hepcidins/genetics ; Homeostasis/genetics ; Humans ; Receptors, Transferrin/genetics ; Recombinant Proteins
Czasopismo naukowe

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