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Tytuł:
Siglecs in health and disease.
Autorzy:
Siddiqui SS; School of Life and Medical Sciences, University of Hertfordshire, College Lane Campus, Hatfield, AL10 9AB, United Kingdom. Electronic address: .
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Źródło:
Molecular aspects of medicine [Mol Aspects Med] 2023 Apr; Vol. 90, pp. 101147. Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Editorial
MeSH Terms:
Sialic Acid Binding Immunoglobulin-like Lectins*
Antigens, CD*
Humans
Opinia redakcyjna
Szczegóły
Tytuł:
Human sialoglycan ligands for immune inhibitory Siglecs.
Autorzy:
Gonzalez-Gil A; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. Electronic address: .
Li TA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. Electronic address: .
Kim J; Department Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. Electronic address: .
Schnaar RL; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. Electronic address: .
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Źródło:
Molecular aspects of medicine [Mol Aspects Med] 2023 Apr; Vol. 90, pp. 101110. Date of Electronic Publication: 2022 Aug 11.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/genetics
Sialic Acid Binding Immunoglobulin-like Lectins*/genetics
Humans ; Immunity ; Inflammation ; Ligands
Czasopismo naukowe
Szczegóły
Tytuł:
Structural insights into the assembly of gp130 family cytokine signaling complexes.
Autorzy:
Zhou Y; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Stevis PE; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Cao J; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Saotome K; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Wu J; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Glatman Zaretsky A; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Haxhinasto S; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Yancopoulos GD; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Murphy AJ; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Sleeman MW; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Olson WC; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
Franklin MC; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA.
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Źródło:
Science advances [Sci Adv] 2023 Mar 15; Vol. 9 (11), pp. eade4395. Date of Electronic Publication: 2023 Mar 17.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/metabolism
Antigens, CD*/metabolism
Cytokine Receptor gp130/metabolism ; Leukemia Inhibitory Factor Receptor alpha Subunit/metabolism ; Cryoelectron Microscopy ; Membrane Glycoproteins/metabolism ; Cytokines/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Screening of EWI-2-Derived Peptides for Targeting Tetraspanin CD81 and Their Effect on Cancer Cell Migration.
Autorzy:
Suwatthanarak T; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1-S1-24 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.; Siriraj Cancer Center, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok 10700, Thailand.; Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok 10700, Thailand.
Usuba K; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1-S1-24 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.
Kuroha K; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1-S1-24 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.
Tanaka M; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1-S1-24 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama-shi 226-8501, Kanagawa, Japan.
Okochi M; Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1-S1-24 O-okayama, Meguro-ku, Tokyo 152-8552, Japan.
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Źródło:
Biomolecules [Biomolecules] 2023 Mar 10; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/metabolism
Neoplasms*
Humans ; Tetraspanin 28/metabolism ; Early Detection of Cancer ; Tetraspanins ; Peptides/pharmacology ; Cell Movement
Czasopismo naukowe
Szczegóły
Tytuł:
Evidence for Epistatic Interaction between HLA-G and LILRB1 in the Pathogenesis of Nonsegmental Vitiligo.
Autorzy:
Oliveira-Caramez ML; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Veiga-Castelli L; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Souza AS; Molecular Genetics and Bioinformatics Laboratory, School of Medicine, São Paulo State University (UNESP), Botucatu 18618-687, SP, Brazil.
Cardili RN; Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Courtin D; Institut de Recherche pour le Développement, UMR 261 MERIT, Université de Paris, F-75006 Paris, France.
Flória-Santos M; Departamento de Enfermagem Materno-Infantil e Saúde Pública-(EERP/ERM), Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Donadi E; Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Giuliatti S; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
Sabbagh A; Institut de Recherche pour le Développement, UMR 261 MERIT, Université de Paris, F-75006 Paris, France.
Castelli EC; Molecular Genetics and Bioinformatics Laboratory, School of Medicine, São Paulo State University (UNESP), Botucatu 18618-687, SP, Brazil.; Pathology Department, School of Medicine, São Paulo State University (UNESP), Botucatu 18618-687, SP, Brazil.
Mendes-Junior CT; Laboratório de Pesquisas Forenses e Genômicas, Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-901, SP, Brazil.
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Źródło:
Cells [Cells] 2023 Feb 15; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*
HLA-G Antigens*/genetics
Leukocyte Immunoglobulin-like Receptor B1*/genetics
Vitiligo*/metabolism
Humans ; Polymorphism, Genetic ; Receptors, Immunologic/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The clinical utility of CD163 in viral diseases.
Autorzy:
Yap YJ; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Wong PF; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: .
AbuBakar S; Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya, 50603 Kuala Lumpur, Malaysia; World Health Organization Collaborating Centre for Arbovirus Reference and Research (Dengue and Severe Dengue) MAA-12, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Sam SS; Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Shunmugarajoo A; Medical Department, Tengku Ampuan Rahimah Hospital, 41200 Klang, Selangor, Malaysia.
Soh YH; Centers for Disease Control and Prevention Unit, Central Melaka District Health Office, Jalan Bukit Baru, 75150 Melaka, Malaysia.
Misbah S; Biological Security and Sustainability Research Group (BIOSES), Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, Malaysia.
Ab Rahman AK; Department of Medicine (Infectious Disease Unit), Sultanah Nur Zahirah Hospital, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, Malaysia.
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Źródło:
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2023 Feb 15; Vol. 541, pp. 117243. Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antigens, CD*/genetics
Virus Diseases*
Humans ; Receptors, Cell Surface/genetics ; Inflammation ; Biomarkers
Czasopismo naukowe
Szczegóły
Tytuł:
Increased CEACAM1 expression on peripheral blood neutrophils in patients with rheumatoid arthritis.
Autorzy:
Matsumoto H; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Fujita Y; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Onizawa M; Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Saito K; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Sumichika Y; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Yoshida S; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Temmoku J; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Matsuoka N; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Yashiro-Furuya M; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Asano T; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Sato S; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Suzuki E; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Machida T; Department of Immunology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Watanabe H; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
Migita K; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Fukushima, Japan.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 14; Vol. 13, pp. 978435. Date of Electronic Publication: 2022 Dec 14 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/genetics
Antigens, CD*/metabolism
Arthritis, Rheumatoid*/genetics
Arthritis, Rheumatoid*/metabolism
Leukocytes, Mononuclear*/metabolism
Humans ; Inflammation/genetics ; Inflammation/metabolism ; Neutrophils/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
CD96 as a Potential Immune Regulator in Cancers.
Autorzy:
Feng S; Department of General, Visceral and Transplant Surgery, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.
Isayev O; Department of Cytology, Embryology and Histology, Azerbaijan Medical University, Baku AZ1022, Azerbaijan.
Werner J; Department of General, Visceral and Transplant Surgery, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, 81377 Munich, Germany.; Bavarian Cancer Research Center (BZKF), 91054 Erlangen, Germany.
Bazhin AV; Department of General, Visceral and Transplant Surgery, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, 81377 Munich, Germany.; Bavarian Cancer Research Center (BZKF), 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 09; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antigens, CD*/metabolism
Neoplasms*/metabolism
Humans ; Immunotherapy ; Killer Cells, Natural ; Nectins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chronic CD40L blockade is required for long-term cardiac allograft survival with a clinically relevant CTLA4-Ig dosing regimen.
Autorzy:
Unger LW; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria.
Muckenhuber M; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
Mahr B; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
Schwarz C; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria.
Pilat N; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
Granofszky N; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
Regele H; Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.
Wekerle T; Department of General Surgery, Division of Transplantation, Medical University of Vienna, Vienna, Austria.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Dec 08; Vol. 13, pp. 1060576. Date of Electronic Publication: 2022 Dec 08 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD40 Ligand*
Antigens, CD*
Animals ; Mice ; Abatacept/therapeutic use ; Calcineurin Inhibitors ; Antibodies, Monoclonal/pharmacology ; Allografts
Czasopismo naukowe
Szczegóły
Tytuł:
Natural LILRB1 D1-D2 variants show frequency differences in populations and bind to HLA class I with various avidities.
Autorzy:
Liu F; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Cocker ATH; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Pugh JL; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Djaoud Z; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Parham P; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Guethlein LA; Department of Structural Biology, School of Medicine, Stanford University, Stanford, CA, 94305, USA. .; Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA. .
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Źródło:
Immunogenetics [Immunogenetics] 2022 Dec; Vol. 74 (6), pp. 513-525. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Receptors, Immunologic*/genetics
Antigens, CD*
Humans ; Leukocyte Immunoglobulin-like Receptor B1/genetics ; Alleles ; HLA-A Antigens
Czasopismo naukowe
Szczegóły
Tytuł:
Optimization of culture conditions for stable expression of recombinant fc-fused human extracellular CD99 in HEK293T cells.
Autorzy:
Thu MM; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Biomedical Technology Research Center, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency at the Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Takheaw N; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Biomedical Technology Research Center, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency at the Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Laopajon W; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Biomedical Technology Research Center, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency at the Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.
Pata S; Division of Clinical Immunology, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Biomedical Technology Research Center, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency at the Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand. Electronic address: supansa_.
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Źródło:
Protein expression and purification [Protein Expr Purif] 2022 Dec; Vol. 200, pp. 106151. Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*
Cell Adhesion Molecules*/metabolism
12E7 Antigen/genetics ; Cytokines ; HEK293 Cells ; Humans ; Immunoglobulin G ; Ligands ; Recombinant Proteins/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns.
Autorzy:
Wang P; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Zhang Z; Department of Burns and Plastic and Wound Repair Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Lin R; Department of Orthopedics, 900th Hospital of Joint Logistics Support Force, Fuzhou, China.
Lin J; Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Liu J; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Zhou X; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Jiang L; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Wang Y; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Deng X; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Lai H; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
Xiao H; Department of Burns and Plastic and Cosmetic Surgery, Xi'an Ninth Hospital, Xi'an, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Nov 28; Vol. 13, pp. 1054407. Date of Electronic Publication: 2022 Nov 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Burns*/genetics
Matrix Attachment Region Binding Proteins*/genetics
Virus Diseases*/genetics
Antigens, Differentiation, T-Lymphocyte*/genetics
Antigens, CD*/genetics
Humans ; Biomarkers ; Immunosuppression Therapy ; Machine Learning ; Molecular Docking Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
CD6-mediated inhibition of T cell activation via modulation of Ras.
Autorzy:
Henriques SN; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Porto, Portugal.; Programa Doutoral em Biologia Molecular e Celular (MCbiology), Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto, Portugal.
Oliveira L; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Porto, Portugal.
Santos RF; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal.; IBMC - Instituto de Biologia Molecular e Celular, Porto, Portugal.
Carmo AM; i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal. .; IBMC - Instituto de Biologia Molecular e Celular, Porto, Portugal. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Nov 21; Vol. 20 (1), pp. 184. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, Differentiation, T-Lymphocyte*/metabolism
Antigens, CD*/metabolism
Humans ; Lymphocyte Activation ; Jurkat Cells ; GTP Phosphohydrolases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of Novel CD39 Inhibitors Based on Virtual Screening and Enzymatic Assays.
Autorzy:
Zhao Y; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Chen X; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Ding Z; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
He C; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Gao G; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Lyu S; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Gao Y; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Du J; School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
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Źródło:
Journal of chemical information and modeling [J Chem Inf Model] 2022 Nov 14; Vol. 62 (21), pp. 5289-5304. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apyrase*/metabolism
Antigens, CD*/metabolism
Molecular Docking Simulation ; Adenosine/metabolism ; Enzyme Assays
Czasopismo naukowe
Szczegóły
Tytuł:
Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells.
Autorzy:
Schanin J; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Korver W; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Brock EC; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Leung J; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Benet Z; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Luu T; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Chang K; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Xu A; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
De Freitas N; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Luehrsen K; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Brehm MA; University of Massachusetts Medical School, Worcester, MA, USA.
Wong A; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA.
Youngblood BA; Allakos, Inc., 825 Industrial Rd Suite, 500, San Carlos, CA, USA. .
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Źródło:
Communications biology [Commun Biol] 2022 Nov 11; Vol. 5 (1), pp. 1226. Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mast Cells*
Antigens, CD*/chemistry
Humans ; Mice ; Animals ; Sialic Acid Binding Immunoglobulin-like Lectins ; Antibodies, Monoclonal/pharmacology ; Epitopes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study.
Autorzy:
Durda P; Department of Pathology and Laboratory Medicine Larner College of Medicine, University of Vermont Burlington VT.
Raffield LM; Department of Genetics University of North Carolina Chapel Hill NC.
Lange EM; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine University of Colorado Anschutz Medical Campus Aurora CO.
Olson NC; Department of Pathology and Laboratory Medicine Larner College of Medicine, University of Vermont Burlington VT.
Jenny NS; Department of Pathology and Laboratory Medicine Larner College of Medicine, University of Vermont Burlington VT.
Cushman M; Department of Pathology and Laboratory Medicine Larner College of Medicine, University of Vermont Burlington VT.; Department of Medicine Larner College of Medicine, University of Vermont Burlington VT.
Deichgraeber P; Steno Diabetes Center Aarhus University Hospital Aarhus Denmark.; Department of Endocrinology and Internal Medicine Aarhus University Hospital Aarhus Denmark.
Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research Copenhagen Denmark.
Jonsson A; Novo Nordisk Foundation Center for Basic Metabolic Research Copenhagen Denmark.
Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research Copenhagen Denmark.
Mychaleckyj JC; Center for Public Health Genomics University of Virginia Charlottesville VA.
Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services University of Washington Seattle WA.
Reiner AP; Department of Epidemiology University of Washington Seattle WA.
Tracy RP; Department of Pathology and Laboratory Medicine Larner College of Medicine, University of Vermont Burlington VT.; Department of Biochemistry Larner College of Medicine, University of Vermont Burlington VT.
Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine University of Colorado Anschutz Medical Campus Aurora CO.
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Źródło:
Journal of the American Heart Association [J Am Heart Assoc] 2022 Nov; Vol. 11 (21), pp. e024374. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/epidemiology
Cardiovascular Diseases*/genetics
Heart Failure*
Antigens, CD*/blood
Aged ; Female ; Humans ; Male ; Antigens, Differentiation, Myelomonocytic/genetics ; Asialoglycoprotein Receptor ; Biomarkers ; Genome-Wide Association Study ; Longitudinal Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Natural killer cell profiles in recurrent pregnancy loss: Increased expression and positive associations with TACTILE and LILRB1.
Autorzy:
Habets DHJ; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; Department of Transplantation Immunology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW school for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Schlütter A; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.
van Kuijk SMJ; Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, the Netherlands.
Spaanderman MEA; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW school for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.; Department of Obstetrics and Gynecology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Al-Nasiry S; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW school for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Wieten L; Department of Transplantation Immunology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW school for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Pokaż więcej
Źródło:
American journal of reproductive immunology (New York, N.Y. : 1989) [Am J Reprod Immunol] 2022 Nov; Vol. 88 (5), pp. e13612. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Abortion, Habitual*
Antigens, CD*/metabolism
Leukocyte Immunoglobulin-like Receptor B1*/metabolism
Leukocytes, Mononuclear*
Female ; Humans ; Pregnancy ; Killer Cells, Natural ; Receptors, Natural Killer Cell
Czasopismo naukowe
Szczegóły
Tytuł:
MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway.
Autorzy:
Wang Q; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China.
Qi C; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China.
Min P; Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Wang Y; Experimental Teaching Center of Basic Medicine, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Ye F; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China.
Xia T; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China.
Zhang Y; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China.
Du J; Department of Physiology, Nanjing Medical University, 101 Longmian Avenue, Jiangning District, Nanjing, 211166, Jiangsu, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Sep 05; Vol. 20 (1), pp. 136. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article; Video-Audio Media; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/genetics
Antigens, CD*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Microfilament Proteins*/genetics
Microfilament Proteins*/metabolism
Oxidoreductases*/genetics
Oxidoreductases*/metabolism
Stomach Neoplasms*/genetics
Stomach Neoplasms*/metabolism
Stomach Neoplasms*/pathology
beta Catenin*/genetics
beta Catenin*/metabolism
cdc42 GTP-Binding Protein*/genetics
cdc42 GTP-Binding Protein*/metabolism
Cell Line, Tumor ; Cell Movement/genetics ; Cell Movement/physiology ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Humans ; Signal Transduction ; Wnt Signaling Pathway
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress.
Autorzy:
Orlik C; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Berschneider KM; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Jahraus B; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Niesler B; Institute of Human Genetics, Department of Human Molecular Genetics and nCounter Core Facility, Heidelberg University, Heidelberg, Germany.
Balta E; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Schäkel K; Department of Dermatology, Heidelberg University Hospital, Heidelberg, Germany.
Schröder-Braunstein J; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Souto-Carneiro MM; Department of Rheumatology, Medical Clinic 5, Heidelberg University Hospital, Heidelberg, Germany.
Samstag Y; Institute of Immunology, Section Molecular Immunology, Heidelberg University Hospital, Heidelberg, Germany.
Pokaż więcej
Źródło:
Frontiers in immunology [Front Immunol] 2022 Oct 24; Vol. 13, pp. 1016112. Date of Electronic Publication: 2022 Oct 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD*/metabolism
Lymphocyte Activation*
Humans ; CD58 Antigens/metabolism ; Keratinocytes ; Oxidative Stress ; TOR Serine-Threonine Kinases/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Genetic diversity of the LILRB1 and LILRB2 coding regions in an admixed Brazilian population sample.
Autorzy:
Oliveira MLG; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Castelli EC; Pathology Department, School of Medicine, São Paulo State University (UNESP), Botucatu, State of São Paulo, Brazil.; Molecular Genetics and Bioinformatics Laboratory, School of Medicine, São Paulo State University (UNESP), Botucatu, State of São Paulo, Brazil.
Veiga-Castelli LC; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Pereira ALE; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Marcorin L; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Carratto TMT; Departamento de Química, Laboratório de Pesquisas Forenses e Genômicas, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Souza AS; Molecular Genetics and Bioinformatics Laboratory, School of Medicine, São Paulo State University (UNESP), Botucatu, State of São Paulo, Brazil.
Andrade HS; Molecular Genetics and Bioinformatics Laboratory, School of Medicine, São Paulo State University (UNESP), Botucatu, State of São Paulo, Brazil.
Simões AL; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Donadi EA; Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Courtin D; MERIT, IRD, Université de Paris, Paris, France.
Sabbagh A; MERIT, IRD, Université de Paris, Paris, France.
Giuliatti S; Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Mendes-Junior CT; Departamento de Química, Laboratório de Pesquisas Forenses e Genômicas, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Pokaż więcej
Źródło:
HLA [HLA] 2022 Oct; Vol. 100 (4), pp. 325-348. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD*/genetics
Leukocyte Immunoglobulin-like Receptor B1*/genetics
Membrane Glycoproteins*/genetics
Receptors, Immunologic*/genetics
Receptors, Immunologic*/metabolism
Alleles ; Amino Acids ; Brazil ; Genetic Variation ; Humans
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 32311

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