Temat: "Antineoplastic Agents" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1.
Autorzy:: Zhao K; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Braun M; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Meyer L; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Otte K; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Raifer H; FACS Core Facility, Philipps University Marburg, Hans-Meerwein-Straße 3, 35043 Marburg, Germany.
Helmprobst F; Department of Neuropathology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Möschl V; Department of Neuropathology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Pagenstecher A; Department of Neuropathology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Urban H; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.; Dr. Senckenberg Institute of Neurooncology, Goethe-University of Frankfurt, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany.
Ronellenfitsch MW; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.; Dr. Senckenberg Institute of Neurooncology, Goethe-University of Frankfurt, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany.
Steinbach JP; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.; Dr. Senckenberg Institute of Neurooncology, Goethe-University of Frankfurt, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany.
Pesek J; Medical Mass Spectrometry Core Facility, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Watzer B; Medical Mass Spectrometry Core Facility, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Nockher WA; Medical Mass Spectrometry Core Facility, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Taudte RV; Medical Mass Spectrometry Core Facility, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.
Neubauer A; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Nimsky C; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Bartsch JW; Department of Neurosurgery, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Rusch T; Department of Hematology, Oncology & Immunology, Philipps University Marburg, Baldingerstraße 1, 35043 Marburg, Germany.; University Cancer Center (UCT) Frankfurt-Marburg, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Apr 04; Vol. 13 (7). Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/drug therapy
Glioblastoma*/metabolism
Antineoplastic Agents*/pharmacology
Amides*
Pyrimidines*
Sulfonamides*
Bridged Bicyclo Compounds, Heterocyclic*
Animals ; Mice ; Temozolomide/pharmacology ; Methotrexate/pharmacology ; Methotrexate/therapeutic use ; Cytarabine/pharmacology ; Cytarabine/therapeutic use ; Antineoplastic Agents, Alkylating/pharmacology ; Cell Line, Tumor ; Apoptosis

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Skocz do pozycji: 2.

Tytuł:: Synergistic effect of cryptotanshinone and temozolomide treatment against human glioblastoma cells.
Autorzy:: Zhu S; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.
Guo J; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.
Yu L; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.
Liu J; Department of Neurosurgery, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei, China.
Chen J; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.
Xin J; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China.
Zhang Y; Medical Services, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China. .
Luo J; Department of Neurosurgery, Taihe Hospital, Hubei University of Medicine, 32 South Renmin Road, Shiyan, 442000, Hubei, China. luojie_.
Duan C; Brain Research Institute, Research Center of Neurological Diseases, Taihe Hospital, Hubei University of Medicine, 32 Renmin South Rd, Shiyan, 442000, Hubei, China. .; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Taihe Hospital of Shiyan, Hubei University of Medicine, Shiyan, 442000, Hubei, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Dec 09; Vol. 13 (1), pp. 21835. Date of Electronic Publication: 2023 Dec 09.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/genetics
Antineoplastic Agents*/pharmacology
Brain Neoplasms*/genetics
Humans ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Antineoplastic Agents, Alkylating/pharmacology ; Antineoplastic Agents, Alkylating/therapeutic use ; Drug Resistance, Neoplasm ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Apoptosis

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Skocz do pozycji: 3.

Tytuł:: Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents.
Autorzy:: Doostmohammadi A; Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.; Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran.
Jooya H; Biochemistry Group, Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Ghorbanian K; Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran.
Gohari S; Department of Biology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Dadashpour M; Department of Medical Biotechnology, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran. .; Cancer Research Center, Semnan University of Medical Sciences, Semnan, Iran. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 15; Vol. 22 (1), pp. 228. Date of Electronic Publication: 2024 Apr 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Humans ; Aged ; Drug Delivery Systems

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Skocz do pozycji: 4.

Tytuł:: Agnostic Administration of Targeted Anticancer Drugs: Looking for a Balance between Hype and Caution.
Autorzy:: Aleksakhina SN; Department of Tumor Growth Biology, N. N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Ivantsov AO; Department of Tumor Growth Biology, N. N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Department of Medical Genetics, St. Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.
Imyanitov EN; Department of Tumor Growth Biology, N. N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.; Department of Medical Genetics, St. Petersburg Pediatric Medical University, 194100 St. Petersburg, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 07; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; B7-H1 Antigen ; BRCA1 Protein ; Protein-Tyrosine Kinases ; BRCA2 Protein ; Proto-Oncogene Proteins

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Skocz do pozycji: 5.

Tytuł:: Lapatinib antitumor effect is associated with PI3K and MAPK pathway: An analysis in human and canine prostate cancer cells.
Autorzy:: Fonseca-Alves CE; Department of Veterinary Surgery and Animal Reproduction, São Paulo State University-UNESP, Botucatu-SP, Brazil.; Institute of Health Sciences, Paulista University-UNIP, Bauru-SP, 17048-290, Brazil.
Leis-Filho AF; Department of Veterinary Surgery and Animal Reproduction, São Paulo State University-UNESP, Botucatu-SP, Brazil.
Lacerda ZA; Department of Veterinary Surgery and Animal Reproduction, São Paulo State University-UNESP, Botucatu-SP, Brazil.
de Faria Lainetti P; Department of Veterinary Surgery and Animal Reproduction, São Paulo State University-UNESP, Botucatu-SP, Brazil.
Amorim RL; Department of Veterinary Clinic, São Paulo State University-UNESP, Botucatu-SP, 18618-681, Brazil.
Rogatto SR; Department of Clinical Genetics, University Hospital of Southern Denmark, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0297043. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Breast Neoplasms*/pathology
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Male ; Humans ; Animals ; Dogs ; Lapatinib/pharmacology ; Lapatinib/therapeutic use ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Receptor, ErbB-2/metabolism ; Quinazolines/pharmacology ; Quinazolines/therapeutic use ; Apoptosis ; Cell Line, Tumor ; Drug Resistance, Neoplasm

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Skocz do pozycji: 6.

Tytuł:: Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells.
Autorzy:: Lv S; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Pan Q; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Lu W; The Fifth Affiliated Hospital of Jinan University (Heyuan Shenhe People's Hospital), Heyuan, 517000, China.
Zhang W; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Wang N; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Huang L; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Li L; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Liu J; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Ma J; Medicine and Health Science College, Guangzhou Huashang College, Guangzhou, People's Republic of China.
Li Z; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Huang Y; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China.
Deng Q; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China. .
Lei X; The Fifth Affiliated Hospital,Guangdong Province & NMPA & State Key Laboratory,School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Apr 01; Vol. 14 (1), pp. 7654. Date of Electronic Publication: 2024 Apr 01.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Ferroptosis*
Humans ; ErbB Receptors/metabolism ; Apoptosis ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Protein Kinase Inhibitors/pharmacology ; Mutation

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Skocz do pozycji: 7.

Tytuł:: Biosynthesis of ZnO, Bi 2 O 3 and ZnO-Bi 2 O 3 bimetallic nanoparticles and their cytotoxic and antibacterial effects.
Autorzy:: Sarani M; Department of Polymer Processing, Iran Polymer and Petrochemical Institute, Tehran, Iran.
Darroudi M; Department of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Naderifar M; Faculty of Nursing and Midwifery, Zabol University of Medical Sciences, Zabol, Iran.
Akbarizadeh MR; Department of pediatric, Amir Al Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran.
Nobre MAL; São Paulo State University (Unesp), School of Technology and Sciences, Presidente Prudente, SP-19060-900, Brazil.
Kruppke B; Max Bergmann Center of Biomaterials, Institute of Materials Science, Technische Universität Dresden, 01069, Dresden, Germany.
Khonakdar HA; Department of Polymer Processing, Iran Polymer and Petrochemical Institute, Tehran, Iran.; Max Bergmann Center of Biomaterials, Institute of Materials Science, Technische Universität Dresden, 01069, Dresden, Germany.
Jazi ME; Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University, Bowling Green, OH-43403, USA.; Pokaż więcej
Źródło:: ChemistryOpen [ChemistryOpen] 2024 Apr; Vol. 13 (4), pp. e202300176. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:: Journal Article
MeSH Terms:: Zinc Oxide*/pharmacology
Zinc Oxide*/chemistry
Zinc Oxide*/metabolism
Nanoparticles*/chemistry
Anti-Infective Agents*/pharmacology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Spectroscopy, Fourier Transform Infrared ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry

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Skocz do pozycji: 8.

Tytuł:: Getting more bang for their buck: BCL2 inhibitors boost dendritic-cell function to enhance anti-cancer immune surveillance.
Autorzy:: Montes-Gómez AE; Cancer Research UK Scotland Institute, Switchback Road, Glasgow, G61 1BD, UK. .; School of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow, G61 1BD, UK. .
Tait SWG; Cancer Research UK Scotland Institute, Switchback Road, Glasgow, G61 1BD, UK. .; School of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow, G61 1BD, UK. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Mar 28; Vol. 22 (1), pp. 317. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:: Letter
MeSH Terms:: Neoplasms*/drug therapy
Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Apoptosis Regulatory Proteins/pharmacology ; Apoptosis Regulatory Proteins/therapeutic use ; Cell Line, Tumor

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Skocz do pozycji: 9.

Tytuł:: A review of the clinical efficacy of FDA-approved antibody‒drug conjugates in human cancers.
Autorzy:: Liu K; Laboratory of Urology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China.; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li M; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Li Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Chen Z; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Tang Y; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Yang M; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Deng G; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China.
Liu H; Laboratory of Urology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524001, China. .; The First Clinical College, Guangdong Medical University, Zhanjiang, 524023, China. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2024 Mar 23; Vol. 23 (1), pp. 62. Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Immunoconjugates*/therapeutic use
Neoplasms*/drug therapy
Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
United States ; Humans ; United States Food and Drug Administration ; Treatment Outcome

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Skocz do pozycji: 10.

Tytuł:: 1,2,3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies.
Autorzy:: Belay Y; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa. .
Muller A; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Mokoena FS; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Adeyinka AS; Department of Chemical Sciences, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Motadi LR; Department of Biochemistry, University of Johannesburg, P.O. Box 524, Auckland Park, 2006, South Africa.
Oyebamiji AK; Industrial Chemistry Programme, Bowen University, PMB 284, Iwo, Osun State, Nigeria.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 23; Vol. 14 (1), pp. 6951. Date of Electronic Publication: 2024 Mar 23.
Typ publikacji:: Journal Article
MeSH Terms:: Schiff Bases*/pharmacology
Schiff Bases*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Humans ; Molecular Docking Simulation ; Triazoles/pharmacology ; Triazoles/chemistry ; Structure-Activity Relationship ; Molecular Structure

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Skocz do pozycji: 11.

Tytuł:: Targeting inflammation as cancer therapy.
Autorzy:: Wang M; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
Chen S; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
He X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China.
Yuan Y; Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China. .
Wei X; Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.17, Block3, Southern Renmin Road, Chengdu, 610041, Sichuan, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of hematology & oncology [J Hematol Oncol] 2024 Mar 22; Vol. 17 (1), pp. 13. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Cytokines/metabolism ; Inflammation/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 12.

Tytuł:: Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition.
Autorzy:: Deben C; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium. .
Boullosa LF; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
Fortes FR; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
De La Hoz EC; Industrial Vision Lab, University of Antwerp, Wilrijk, Belgium.
Le Compte M; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
Seghers S; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
Peeters M; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
Vanlanduit S; Industrial Vision Lab, University of Antwerp, Wilrijk, Belgium.
Lin A; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Plasma Lab for Applications in Sustainability and Medicine ANTwerp (PLASMANT), University of Antwerp, Wilrijk, Belgium.
Dijkstra KK; Department of Molecular Oncology and Immunology, the Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.
Van Schil P; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.
Hendriks JMH; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium.
Prenen H; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Department of Oncology, Multidisciplinary Oncological Center Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Roeyen G; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Department of Hepatobiliary Transplantation and Endocrine Surgery, University Hospital Antwerp (UZA), Edegem, Belgium.
Lardon F; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.
Smits E; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Center for Cell Therapy and Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium.; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Mar 22; Vol. 43 (1), pp. 88. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Carcinoma, Pancreatic Ductal*/drug therapy
Adenocarcinoma*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Carbonic Anhydrases*
Humans ; Auranofin/pharmacology ; Auranofin/therapeutic use ; Proto-Oncogene Proteins c-akt/metabolism ; Drug Repositioning ; Lung/pathology ; Biomarkers ; Organoids/metabolism

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Skocz do pozycji: 13.

Tytuł:: Unified Synthesis and Biological Evaluation of Makaluvamine J and Its Analogs.
Autorzy:: Kiichi Y; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan.
Fukuoka K; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan.
Kitano A; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan.
Ishino K; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan.
Kotoku N; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga 525-8577, Japan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 20; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrroloiminoquinones*/chemistry
Pyrroloiminoquinones*/pharmacology
Porifera*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Alkaloids*/chemistry
Animals ; Humans ; Structure-Activity Relationship

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Skocz do pozycji: 14.

Tytuł:: The Transcriptome of BT-20 Breast Cancer Cells Exposed to Curcumin Analog NC2603 Reveals a Relationship between EGR3 Gene Modulation and Cell Migration Inhibition.
Autorzy:: Nishimura FG; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Sampaio BB; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
do Couto GO; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
da Silva AD; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
da Silva WJ; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Peronni KC; Instituto para Pesquisa do Cancêr (IPEC), Guarapuava 85100-000, Brazil.
Evangelista AF; Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Manguinhos, Rio de Janeiro 21041-210, Brazil.
Hossain M; School of Sciences, Indiana University Kokomo, Kokomo, IN 46904, USA.
Dimmock JR; College of Pharmacy and Nutrition, University of Saskatchewan (USask), Saskatoon, SK S7N 5E5, Canada.
Bandy B; College of Pharmacy and Nutrition, University of Saskatchewan (USask), Saskatoon, SK S7N 5E5, Canada.
Beleboni RO; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Marins M; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.
Fachin AL; Unidade de Biotecnologia, Universidade de Ribeirão Preto (UNAERP), Ribeirao Preto 14096-900, Brazil.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 19; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Female ; Cell Migration Inhibition ; Transcriptome ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Apoptosis ; Early Growth Response Protein 3/metabolism ; Early Growth Response Protein 3/pharmacology

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Skocz do pozycji: 15.

Tytuł:: The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer.
Autorzy:: Hagi T; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Vangveravong S; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Takchi R; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Gong Q; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.
Goedegebuure SP; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA.; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.
Tiriac H; Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California San Diego, San Diego, CA, USA, San Diego, USA.
Van Tine BA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.; Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.
Powell MA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Hawkins WG; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA. .; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA. .
Spitzer D; Department of Surgery, Washington University School of Medicine, S. Euclid Avenue, St. Louis, MO, 63110, USA. .; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 16; Vol. 14 (1), pp. 6373. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/metabolism
Humans ; Animals ; Mice ; Female ; Apoptosis ; Inhibitor of Apoptosis Proteins/metabolism ; Caspases/metabolism ; Cell Line, Tumor

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Skocz do pozycji: 16.

Tytuł:: Allicin and Cancer Hallmarks.
Autorzy:: Talib WH; Faculty of Allied Medical Sciences, Applied Science Private University, Amman 11931, Jordan.
Baban MM; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
Azzam AO; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
Issa JJ; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
Ali AY; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
AlSuwais AK; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
Allala S; Department of Clinical Pharmacy and Therapeutics, Applied Science University, Amman 11931, Jordan.
Al Kury LT; Department of Health Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 15; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Plants, Medicinal*
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Colonic Neoplasms*/drug therapy
Garlic*/chemistry
Male ; Humans ; Plant Extracts/chemistry ; Prospective Studies ; Sulfinic Acids/chemistry ; Disulfides

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Skocz do pozycji: 17.

Tytuł:: Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells.
Autorzy:: Elradi M; Biotechnology Program, American University in Cairo, New Cairo, Egypt.
Ahmed AI; Biology Department, American University in Cairo, New Cairo, Egypt.
Saleh AM; Biology Department, American University in Cairo, New Cairo, Egypt.
Abdel-Raouf KMA; Biology Department, American University in Cairo, New Cairo, Egypt.
Berika L; Biology Department, American University in Cairo, New Cairo, Egypt.
Daoud Y; Biology Department, American University in Cairo, New Cairo, Egypt.
Amleh A; Biotechnology Program, American University in Cairo, New Cairo, Egypt. .; Biology Department, American University in Cairo, New Cairo, Egypt. .; Pokaż więcej
Źródło:: BMC biotechnology [BMC Biotechnol] 2024 Mar 15; Vol. 24 (1), pp. 14. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Anti-Infective Agents*/pharmacology
Salts*
Animals ; Mice ; Humans ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 3/pharmacology ; Survivin/genetics ; Survivin/metabolism ; Survivin/pharmacology ; Escherichia coli/metabolism ; Antimicrobial Peptides ; Cell Line, Tumor ; Indian Ocean ; Ki-67 Antigen/metabolism ; Staphylococcus aureus ; Apoptosis ; Peptides/pharmacology ; Peptides/metabolism ; Annexins/pharmacology

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Skocz do pozycji: 18.

Tytuł:: Modeling antibody drug conjugate potential using a granzyme B antibody fusion protein.
Autorzy:: Anderson TS; Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 1718 Pine Street, Office 1306, Abilene, TX, 79601, USA.
McCormick AL; Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 1718 Pine Street, Office 1306, Abilene, TX, 79601, USA.
Smith SL; Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 1718 Pine Street, Office 1306, Abilene, TX, 79601, USA.
Lowe DB; Department of Immunotherapeutics and Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 1718 Pine Street, Office 1306, Abilene, TX, 79601, USA. .; Pokaż więcej
Źródło:: BMC biology [BMC Biol] 2024 Mar 14; Vol. 22 (1), pp. 66. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Immunoconjugates*/pharmacology
Immunoconjugates*/chemistry
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Granzymes ; alpha-Fetoproteins ; Antibodies, Monoclonal ; Cell Line, Tumor

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Skocz do pozycji: 19.

Tytuł:: Advances in AI for Protein Structure Prediction: Implications for Cancer Drug Discovery and Development.
Autorzy:: Qiu X; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.
Li H; Department of Computer Science and Engineering, University of California Riverside, Riverside, CA 92521, USA.
Ver Steeg G; Department of Computer Science and Engineering, University of California Riverside, Riverside, CA 92521, USA.
Godzik A; Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2024 Mar 12; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Neoplasms*/drug therapy
Humans ; Drug Discovery ; Drug Development ; Artificial Intelligence

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Skocz do pozycji: 20.

Tytuł:: Static magnetic field reduces cisplatin resistance via increasing apoptosis pathways and genotoxicity in cancer cell lines.
Autorzy:: Zafari J; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. .
Rastegar-Pouyani N; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Javani Jouni F; Department of Biochemistry and Biophysics, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Najjar N; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Azarshin SZ; Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jafarzadeh E; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Abdolmaleki P; Department of Biophysics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Hoseini Shirazi F; Pharmaceutical Sciences Research Center and Department of Toxicology and Pharmacology, Faculty of Pharmacy, Shahid Behesthi University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5792. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Ovarian Neoplasms*/pathology
Humans ; Female ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Apoptosis ; DNA Damage ; Magnetic Fields

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