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Wyszukujesz frazę ""Antineoplastic Agents pharmacology"" wg kryterium: Temat


Tytuł :
An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation
Autorzy :
Castiello, Luciano
Zevini, Alessandra
Vulpis, Elisabetta
Muscolini, Michela
Ferrari, Matteo
Palermo, Enrico
Peruzzi, Giovanna
Krapp, Christian
Jakobsen, Martin
Olagnier, David
Zingoni, Alessandra
Santoni, Angela
Hiscott, John
Pokaż więcej
Temat :
Cell Differentiation
Immunogenic cell death
Interferons/metabolism
Antigen Presentation/drug effects
Proto-Oncogene Proteins c-bcl-2/metabolism
HMGB1 Protein/metabolism
Apoptosis/drug effects
Interferons
Dendritic cells
Alarmins/immunology
BLOCKADE
SUPPRESSION
Calreticulin/metabolism
Molecular Targeted Therapy
RIG-I
Melanoma/drug therapy
Apoptosis Regulatory Proteins/metabolism
Dendritic Cells/immunology
Signal Transduction
Proto-Oncogene Proteins/metabolism
Caspase 3/metabolism
DEAD Box Protein 58/antagonists & inhibitors
Antineoplastic Agents/pharmacology
INTERFERON
ANTIVIRAL RESPONSE
Nelfinavir/analogs & derivatives
Cell Line, Tumor
chemical and pharmacologic phenomena
Immunization
Cancer immunotherapy
DEFECTS
Humans
Źródło :
Castiello, L, Zevini, A, Vulpis, E, Muscolini, M, Ferrari, M, Palermo, E, Peruzzi, G, Krapp, C, Jakobsen, M, Olagnier, D, Zingoni, A, Santoni, A & Hiscott, J 2019, ' An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation ', Cancer Immunology, Immunotherapy, vol. 68, no. 9, pp. 1479-1492 . https://doi.org/10.1007/s00262-019-02380-2
Tytuł :
Multifaceted Study on a Cytochalasin Scaffold: Lessons on Reactivity, Multidentate Catalysis, and Anticancer Properties
Autorzy :
Gayraud, Oscar
Prévost, Sébastien
Sabbah, Michèle
Escargueil, Alexandre
Le Clainche, Christophe
Gautreau, Alexis
Blanchard, Florent
Frison, Gilles
Nay, Bastien
Zaghouani, Mehdi
Jactel, Vincent
Dezaire, Ambre
Lai, Thanh-Lan
Rocques, Nathalie
Romero, Stéphane
Pokaż więcej
Temat :
MESH: Stereoisomerism
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
MESH: Cytochalasins/chemistry
MESH: Crystallography, X-Ray
MESH: Palladium/chemistry
MESH: Thiourea/chemistry
[SDV.BC]Life Sciences [q-bio]/Cellular Biology
Organocatalysis
Density functional calculations
Natural products
MESH: Cytochalasins/pharmacology
[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]
MESH: Copper/chemistry
MESH: Actin Cytoskeleton/drug effects
[SDV.CAN]Life Sciences [q-bio]/Cancer
[CHIM]Chemical Sciences
Medium-ring compounds
MESH: Hydrogen Bonding
MESH: Cell Survival/drug effects
MESH: Cycloaddition Reaction
[CHIM.ORGA]Chemical Sciences/Organic chemistry
MESH: Humans
MESH: Antineoplastic Agents/pharmacology
MESH: Antineoplastic Agents/chemistry
MESH: Catalysis
MESH: Thermodynamics
Antitumor agents
[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology
MESH: Antineoplastic Agents/chemical synthesis
MESH: Cytochalasins/chemical synthesis
MESH: Molecular Conformation
[CHIM.CATA]Chemical Sciences/Catalysis
MESH: Cell Line, Tumor
Źródło :
Chemistry - A European Journal, Wiley-VCH Verlag, 2018, 24 (62), pp.16686-16691. ⟨10.1002/chem.201804023⟩
Chemistry - A European Journal, Wiley-VCH Verlag, 2018, 24 (62), pp.16686 - 16691. ⟨10.1002/chem.201804023⟩
Chemistry - A European Journal
Tytuł :
Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer
Autorzy :
Chong, Irene Yushing
Aronson, Lauren
Bryant, Hanna
Gulati, Aditi
Campbell, James
Elliott, Richard
Pettitt, Stephen
Wilkerson, Paul
Lambros, Maryou B
Reis-Filho, Jorge S
Ramessur, Anisha
Davidson, Michael
Chau, Ian
Cunningham, David
Ashworth, Alan
Lord, Christopher J
Pokaż więcej
Temat :
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Drug Discovery/methods
Esophageal Neoplasms/drug therapy
Humans
Pharmacogenetics
Pharmacogenomic Testing/methods
Proto-Oncogene Proteins c-myc/genetics
Pyrazoles/pharmacology
Pyrimidines/pharmacology
RNA Interference/drug effects
Receptor, ErbB-2/genetics
Signal Transduction/genetics
Xenograft Model Antitumor Assays
Źródło :
Chong, I Y, Aronson, L, Bryant, H, Gulati, A, Campbell, J, Elliott, R, Pettitt, S, Wilkerson, P, Lambros, M B, Reis-Filho, J S, Ramessur, A, Davidson, M, Chau, I, Cunningham, D, Ashworth, A & Lord, C J 2018, ' Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer ', Gut, vol. 67, no. 10, pp. 1780-1792 . https://doi.org/10.1136/gutjnl-2017-314408
Opis pliku :
application/pdf
Tytuł :
Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics
Autorzy :
Williams, David S.
Ridolfo, Roxane
Ede, Benjamin C.
Diamanti, Paraskevi
White, Paul B.
Perriman, Adam W.
van Hest, Jan C. M.
Blair, Allison
Pokaż więcej
Temat :
Drug Delivery Systems
Nanoparticles/chemistry
Biotechnology
parthenolide
Engineering (miscellaneous)
Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy
drug delivery
Polymers/chemistry
Research Support, Non-U.S. Gov't
Chemistry(all)
Drug Liberation
Biomaterials
Biocompatible Materials/chemistry
Drug Carriers/chemistry
Sesquiterpenes/pharmacology
nanomedicine
Antineoplastic Agents/pharmacology
Cell Line, Tumor
Materials Science(all)
self-assembly
acute leukemia
Water/chemistry
Journal Article
Humans
Źródło :
Small, 14(32). Wiley-VCH Verlag
Ridolfo, R, Ede, B C, Diamanti, P, White, P B, Perriman, A W, van Hest, J C M, Blair, A & Williams, D S 2018, ' Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics ', Small, vol. 14, no. 32, 1703774 . https://doi.org/10.1002/smll.201703774
Opis pliku :
application/pdf
Tytuł :
Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity
Autorzy :
Ek, Sara
Freiburghaus, Catja
Emruli, Venera Kuci
Johansson, Angelica
Eskelund, Christian Winther
Grønbæk, Kirsten
Olsson, Roger
Ek, Fredrik
Jerkeman, Mats
Pokaż więcej
Temat :
Cytarabine
Research Article
SPIB
Gene Expression Regulation, Neoplastic/drug effects
Lymphoma, Mantle-Cell/genetics
DCK
Research Support, Non-U.S. Gov't
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Histone Deacetylase Inhibitors/pharmacology
Signal Transduction/drug effects
Deoxycytidine Kinase/genetics
MCL
Transcription Factors/genetics
Bortezomib/pharmacology
Cytarabine/pharmacology
Dose-Response Relationship, Drug
Transcription, Genetic
NF-κB
Drug Resistance, Neoplasm/drug effects
Antineoplastic Agents/pharmacology
DNA-Binding Proteins/genetics
NF-kappa B/metabolism
Cell Line, Tumor
RC254-282
Journal Article
Gene Expression Profiling
Humans
Źródło :
BMC Cancer, Vol 18, Iss 1, Pp 1-17 (2018)
Freiburghaus, C, Emruli, V K, Johansson, A, Eskelund, C W, Grønbæk, K, Olsson, R, Ek, F, Jerkeman, M & Ek, S 2018, ' Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity ', BMC Cancer, vol. 18, no. 1, 466 . https://doi.org/10.1186/s12885-018-4346-1
Opis pliku :
application/pdf
Tytuł :
Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia
Autorzy :
Turner, Joseph D
Pionnier, Nicolas
Furlong-Silva, Julio
Sjoberg, Hanna
Cross, Stephen
Halliday, Alice
Guimaraes, Ana F
Cook, Darren A N
Steven, Andrew
Van Rooijen, Nico
Allen, Judith E
Pokaż więcej
Temat :
respiratory system
Brugia malayi/drug effects
Eosinophilia/drug therapy
Macrophages/drug effects
Filariasis/drug therapy
Antineoplastic Agents/pharmacology
Mice
Research Support, Non-U.S. Gov't
Mice, Inbred BALB C
Mice, SCID
Interleukin-4/pharmacology
parasitic diseases
Journal Article
Animals
Cytokines/genetics
Female
Male
Receptors, CCR3/genetics
Źródło :
Turner, J D, Pionnier, N, Furlong-Silva, J, Sjoberg, H, Cross, S, Halliday, A, Guimaraes, A F, Cook, D A N, Steven, A, Van Rooijen, N & Allen, J E 2018, ' Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia ', PLoS Pathogens, vol. 14, no. 3, e1006949 . https://doi.org/10.1371/journal.ppat.1006949,">https://doi.org/10.1371/journal.ppat.1006949, https://doi.org/10.1371/journal.ppat.1006949
Opis pliku :
application/pdf
Tytuł :
The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain
Autorzy :
Appel, Camilla Kristine
Gallego-Pedersen, Simone
Andersen, Line
Blancheflor Kristensen, Sophie
Ding, Ming
Falk, Sarah
Sayilekshmy, Manasi
Gabel-Jensen, Charlotte
Heegaard, Anne-Marie
Pokaż więcej
Temat :
Dasatinib/pharmacology
hemic and lymphatic diseases
Pain Management/methods
Luciferases/genetics
Animals
Rats
Female
Rats, Sprague-Dawley
Bone Neoplasms/complications
Osteosarcoma/complications
Mammary Neoplasms, Animal/complications
Signal Transduction
Tartrate-Resistant Acid Phosphatase/antagonists & inhibitors
Receptors, N-Methyl-D-Aspartate/genetics
src-Family Kinases/antagonists & inhibitors
Antineoplastic Agents/pharmacology
Pain Measurement/methods
Article
Administration, Oral
Cell Line, Tumor
Bone and Bones/drug effects
Osteoclasts/drug effects
Genes, Reporter
Gene Expression Regulation, Neoplastic
Pain/drug therapy
Journal Article
Phosphorylation/drug effects
Protein Kinase Inhibitors/pharmacology
Źródło :
Appel, C K, Gallego-Pedersen, S, Andersen, L, Kristensen, S B, Ding, M, Falk, S, Sayilekshmy, M, Gabel-Jensen, C & Heegaard, A-M 2017, ' The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain ', Scientific Reports, vol. 7, no. 1, 4792 . https://doi.org/10.1038/s41598-017-05029-1
Appel, C K, Gallego-Pedersen, S, Andersen, L, Blancheflor Kristensen, S, Ding, M, Falk, S, Sayilekshmy, M, Gabel-Jensen, C & Heegaard, A-M 2017, ' The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain ', Scientific Reports, vol. 7, 4792, pp. 1-14 . https://doi.org/10.1038/s41598-017-05029-1
Opis pliku :
application/pdf
Tytuł :
Evaluation of anti-diabetic and anti-tumoral activities of bioactive compounds from Phoenix dactylifera L’s leaf: In vitro and in vivo approach
Autorzy :
Chakroun, Mouna
Khemakhem, Bassem
Mabrouk, Hazem Ben
El Abed, Hanen
Makni, Mohamed
Bouaziz, Mohamed
Drira, Noureddine
Marrakchi, Naziha
Mejdoub, Hafedh
Pokaż więcej
Temat :
inhibitors
MESH: Animals
MESH: Phoeniceae/chemistry
[SDV.BV]Life Sciences [q-bio]/Vegetal Biology
MESH: Male
MESH: Polyphenols/therapeutic use
MESH: Diabetes Mellitus, Experimental/drug therapy
MESH: Plant Leaves/chemistry
LC–MS/MS analysis
MESH: Diabetes Mellitus, Experimental/complications
MESH: Phytochemicals/therapeutic use
MESH: Hypoglycemic Agents/therapeutic use
MESH: Plant Extracts/therapeutic use
MESH: alpha-Glucosidases/metabolism
Cytotoxic activity
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
IGR-39 cancer cell lines
MESH: Hypoglycemic Agents/pharmacology
MESH: Enzyme Assays
MESH: Plant Extracts/pharmacology
MESH: Hyperglycemia/complications
MESH: Diabetes Mellitus, Type 2/drug therapy
MESH: Hyperglycemia/drug therapy
MESH: Postprandial Period
MESH: Humans
Phoenix dactylifera L.’s leaves
MESH: Antineoplastic Agents/pharmacology
MESH: Tandem Mass Spectrometry
MESH: Diabetes Mellitus, Type 2/complications
MESH: Cell Death/drug effects
MESH: Phytochemicals/pharmacology
MESH: Chromatography, Liquid
MESH: Polyphenols/pharmacology
MESH: Mice
α-Glucosidase and α-Amylase
MESH: Antineoplastic Agents/therapeutic use
MESH: Phytotherapy
[SDV]Life Sciences [q-bio]
MESH: alpha-Amylases/metabolism
Antidiabetic activity
MESH: Cell Line, Tumor
Źródło :
Biomedicine and Pharmacotherapy, Elsevier Masson, 2016, 84, pp.415 - 422. ⟨10.1016/j.biopha.2016.09.062⟩
Biomedicine and Pharmacotherapy

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