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Tytuł:
What are patients' experiences of discontinuing clozapine and how does this impact their views on subsequent treatment?
Autorzy:
Southern J; Aston University, Birmingham, B4 7ET, England. .; Cheshire and Wirral Partnership NHS Foundation Trust, Chester, CH2 1BQ, England. .
Elliott P; Cheshire and Wirral Partnership NHS Foundation Trust, Chester, CH2 1BQ, England.
Maidment I; Aston University, Birmingham, B4 7ET, England.
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 May 22; Vol. 23 (1), pp. 353. Date of Electronic Publication: 2023 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
Clozapine*/adverse effects
Schizophrenia*/drug therapy
Schizophrenia*/chemically induced
Antipsychotic Agents*/adverse effects
Male ; Female ; Humans ; Adult ; Middle Aged ; Aged ; Treatment Outcome ; Wales
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development and Characterization of Novel Selective, Non-Basic Dopamine D 2 Receptor Antagonists for the Treatment of Schizophrenia.
Autorzy:
Stępnicki P; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Wośko S; Laboratory of Preclinical Testing, Chair and Department of Applied and Social Pharmacy, Faculty of Pharmacy, Medical University of Lublin, Chodźki 1, PL-20093 Lublin, Poland.
Bartyzel A; Department of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University in Lublin, Maria Curie-Skłodowska Sq. 2, PL-20031 Lublin, Poland.
Zięba A; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Bartuzi D; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124 Uppsala, Sweden.
Szałaj K; Department of Bioanalytics, Chair of Dietetics and Bioanalytics, Faculty of Biomedicine, Medical University of Lublin, Jaczewskiego 8b St., PL-20090 Lublin, Poland.
Wróbel TM; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Fornal E; Department of Bioanalytics, Chair of Dietetics and Bioanalytics, Faculty of Biomedicine, Medical University of Lublin, Jaczewskiego 8b St., PL-20090 Lublin, Poland.
Carlsson J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, 75124 Uppsala, Sweden.
Kędzierska E; Department of Pharmacology and Pharmacodynamics, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.
Poleszak E; Laboratory of Preclinical Testing, Chair and Department of Applied and Social Pharmacy, Faculty of Pharmacy, Medical University of Lublin, Chodźki 1, PL-20093 Lublin, Poland.
Castro M; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, Avda de Barcelona, E-15782 Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Travesía da Choupana s/n, E-15706 Santiago de Compostela, Spain.
Kaczor AA; Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodźki St., PL-20093 Lublin, Poland.; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 20; Vol. 28 (10). Date of Electronic Publication: 2023 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Schizophrenia*/drug therapy
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Antipsychotic Agents*/chemistry
Animals ; Dopamine/therapeutic use ; Receptors, Dopamine ; Radioligand Assay ; Receptors, Dopamine D3/therapeutic use
Czasopismo naukowe
Szczegóły
Tytuł:
Gut microbiome profiles may be related to atypical antipsychotic associated overweight in Asian children with psychiatric disorder: a preliminary study.
Autorzy:
Hao SR; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Zhou YY; Department of Medical Psychology, The First Affiliated Hospital, Hainan Medical University, Haikou, Hainan, China.; Department of Child Psychiatry, Hangzhou Seventh People's Hospital, Hangzhou, Zhejiang, China.
Zhang X; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.; Department of Infectious Diseases, The Affiliated Hangzhou First People's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Jiang HY; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 May 03; Vol. 13, pp. 1124846. Date of Electronic Publication: 2023 May 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gastrointestinal Microbiome*/physiology
Antipsychotic Agents*/adverse effects
Mental Disorders*
Humans ; Child ; Overweight/chemically induced ; Overweight/drug therapy ; Overweight/microbiology ; Cross-Sectional Studies ; Bacteria/genetics ; RNA, Ribosomal, 16S/genetics ; Feces/microbiology
Czasopismo naukowe
Szczegóły
Tytuł:
Antipsychotics Induced Reproductive Toxicity by Stimulating Oxidative Stress: A Comparative in Vivo and in Silico Study.
Autorzy:
Dincer B; Department of Pharmacology, Faculty of Pharmacy, Ondokuz Mayıs University, Samsun, 55020, Turkey.
Bulent Yazici A; Department of Psychiatry, Faculty of Medicine, Sakarya University, Sakarya, 54050, Turkey.
Cinar I; Department of Pharmacology, Faculty of Medicine, Kastamonu University, Kastamonu, 37150, Turkey.
Toktay E; Department of Histology and Embryology, Faculty of Medicine, Kafkas University, Kars, 36100, Turkey.
Selli J; Department of Histology and Embryology, Faculty of Medicine, Alanya Aladdin Keykubat University, Antalya, 07425, Turkey.
Cadirci E; Department of Pharmacology, Faculty of Medicine, Ataturk University, Erzurum, 25240, Turkey.
Bayraktutan Z; Department of Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, 25240, Turkey.
Yazici E; Department of Psychiatry, Faculty of Medicine, Sakarya University, Sakarya, 54050, Turkey.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 May; Vol. 20 (5), pp. e202201190. Date of Electronic Publication: 2023 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Antipsychotic Agents*/toxicity
Antipsychotic Agents*/therapeutic use
Male ; Rats ; Animals ; Risperidone/toxicity ; Risperidone/therapeutic use ; Haloperidol/toxicity ; Haloperidol/therapeutic use ; Quetiapine Fumarate ; Aripiprazole ; Semen
Czasopismo naukowe
Szczegóły
Tytuł:
Psychopharmacological treatment of disruptive behavior in youths: systematic review and network meta-analysis.
Autorzy:
Seok JW; Department of Psychiatry, University of Nebraska Medical Center, 985578 Nebraska Medical Center, Omaha, NE, 68198-5578, USA.
Soltis-Vaughan B; Department of Psychiatry, University of Nebraska Medical Center, 985578 Nebraska Medical Center, Omaha, NE, 68198-5578, USA.
Lew BJ; Department of Psychiatry, University of Nebraska Medical Center, 985578 Nebraska Medical Center, Omaha, NE, 68198-5578, USA.
Ahmad A; Department of Psychiatry, University of Nebraska Medical Center, 985578 Nebraska Medical Center, Omaha, NE, 68198-5578, USA.
Blair RJR; Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark, Copenhagen, Denmark.
Hwang S; Department of Psychiatry, University of Nebraska Medical Center, 985578 Nebraska Medical Center, Omaha, NE, 68198-5578, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Apr 28; Vol. 13 (1), pp. 6921. Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Attention Deficit Disorder with Hyperactivity*/drug therapy
Problem Behavior*
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Central Nervous System Stimulants*/therapeutic use
Adolescent ; Humans ; Network Meta-Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A pilot-study to examine motor cortical plasticity as a neuro-marker of antipsychotic treatment response in schizophrenia.
Autorzy:
Sachdeva A; Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India.
Mehta UM; Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India. Electronic address: .
Thirthalli J; Department of Psychiatry, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore 560029, India.
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Źródło:
Asian journal of psychiatry [Asian J Psychiatr] 2023 Apr; Vol. 82, pp. 103515. Date of Electronic Publication: 2023 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Schizophrenia*/drug therapy
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Humans ; Pilot Projects ; Neuronal Plasticity/physiology ; Transcranial Magnetic Stimulation ; Evoked Potentials, Motor/physiology
Czasopismo naukowe
Szczegóły
Tytuł:
Estradiol and raloxifene as adjunctive treatment for women with schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials.
Autorzy:
Li Z; Department of Psychiatry, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Wang Y; Department of Psychiatry, The First Hospital of China Medical University, Shenyang, People's Republic of China.; School of Public Health, China Medical University, Shenyang, People's Republic of China.
Wang Z; Department of Psychiatry, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Kong L; Department of Psychiatry, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Liu L; Department of Psychiatry, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Li L; Shenyang Women's and Children's Hospital, Shenyang, People's Republic of China.
Tang Y; Department of Psychiatry and Geriatrics, The First Hospital of China Medical University, Shenyang, People's Republic of China.
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Źródło:
Acta psychiatrica Scandinavica [Acta Psychiatr Scand] 2023 Apr; Vol. 147 (4), pp. 360-372. Date of Electronic Publication: 2023 Jan 27.
Typ publikacji:
Meta-Analysis; Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Schizophrenia*/drug therapy
Schizophrenia*/diagnosis
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Humans ; Female ; Raloxifene Hydrochloride/pharmacology ; Raloxifene Hydrochloride/therapeutic use ; Estradiol ; Drug Therapy, Combination ; Postmenopause ; Double-Blind Method ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy and safety of adjunctive therapy with fingolimod in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial.
Autorzy:
Karbalaee M; Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Jameie M; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran; Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran.
Amanollahi M; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
TaghaviZanjani F; Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Parsaei M; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Basti FA; Islamic Azad University, Tehran Medical Branch, Tehran, Iran.
Mokhtari S; Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Moradi K; Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ardakani MK; Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Akhondzadeh S; Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło:
Schizophrenia research [Schizophr Res] 2023 Apr; Vol. 254, pp. 92-98. Date of Electronic Publication: 2023 Feb 18.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Schizophrenia*/etiology
Antipsychotic Agents*/adverse effects
Humans ; Risperidone/therapeutic use ; Fingolimod Hydrochloride/adverse effects ; Treatment Outcome ; Drug Therapy, Combination ; Double-Blind Method
Czasopismo naukowe
Szczegóły
Tytuł:
Resting-state functional connectivity correlates of antipsychotic treatment in unmedicated schizophrenia.
Autorzy:
Sreeraj VS; InSTAR Clinic and Translational Psychiatry Lab, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India. Electronic address: .
Shivakumar V; InSTAR Clinic and Translational Psychiatry Lab, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India; Department of Integrative Medicine, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Bhalerao GV; Department of Psychiatry, University of Oxford, Oxford, UK.
Kalmady SV; Alberta Machine Intelligence Institute, Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada; Canadian VIGOUR Centre, University of Alberta, Edmonton, Alberta, Canada.
Narayanaswamy JC; Goulburn Valley Health, Shepparton, VIC, Australia.
Venkatasubramanian G; InSTAR Clinic and Translational Psychiatry Lab, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, India.
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Źródło:
Asian journal of psychiatry [Asian J Psychiatr] 2023 Apr; Vol. 82, pp. 103459. Date of Electronic Publication: 2023 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Schizophrenia*/diagnostic imaging
Schizophrenia*/drug therapy
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Connectome*/methods
Humans ; Brain/diagnostic imaging ; Temporal Lobe ; Magnetic Resonance Imaging
Czasopismo naukowe
Szczegóły
Tytuł:
Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID-ICU trial.
Autorzy:
Andersen-Ranberg NC; Department of Anaesthesiology and Intensive Care Medicine, Zealand University Hospital, Lykkebækvej 1, 4600, Køge, Denmark. .; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark. .
Poulsen LM; Department of Anaesthesiology and Intensive Care Medicine, Zealand University Hospital, Lykkebækvej 1, 4600, Køge, Denmark.; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.
Perner A; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Hästbacka J; Department of Anaesthesiology, Helsinki University Hospital, Helsinki, Finland.
Morgan M; Department of Intensive Care, Cardiff University Hospital of Wales, Cardiff, UK.
Citerio G; Università Milano-Bicocca, Milan, Italy.; Department of Neuroscience, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Collet MO; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Weber SO; Department of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Andreasen AS; Department of Anaesthesiology and Intensive Care, Copenhagen University Hospital-Herlev, Herlev, Denmark.
Bestle M; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Anaesthesiology and Intensive Care, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Uslu B; Department of Anaesthesiology and Intensive Care Medicine, Zealand University Hospital, Roskilde, Denmark.
Pedersen HS; Department of Anaesthesiology and Intensive Care, Nykøbing Falster Sygehus, Nykøbing Falster, Denmark.
Nielsen LG; Department of Anaesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.
Damgaard K; Department of Anaesthesiology and Intensive Care, Hjørring Hospital, Hjørring, Denmark.
Jensen TB; Department of Anaesthesiology and Intensive Care, Gødstrup Hospital, Herning, Denmark.
Sommer T; Department of Anaesthesiology and Intensive Care Medicine, Hospital Sønderjylland, Aabenraa, Denmark.
Dey N; Department of Anaesthesiology and Intensive Care, Gødstrup Hospital, Herning, Denmark.
Mathiesen O; Department of Anaesthesiology and Intensive Care Medicine, Zealand University Hospital, Lykkebækvej 1, 4600, Køge, Denmark.; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Granholm A; Collaboration for Research in Intensive Care (CRIC), Copenhagen, Denmark.; Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
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Źródło:
Intensive care medicine [Intensive Care Med] 2023 Apr; Vol. 49 (4), pp. 411-420. Date of Electronic Publication: 2023 Mar 27.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Antipsychotic Agents*/therapeutic use
Antipsychotic Agents*/adverse effects
Delirium*/drug therapy
Delirium*/chemically induced
Adult ; Humans ; Haloperidol/therapeutic use ; Haloperidol/adverse effects ; Bayes Theorem ; Intensive Care Units
Czasopismo naukowe
Szczegóły
Tytuł:
Canonical and Non-Canonical Antipsychotics' Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia.
Autorzy:
de Bartolomeis A; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
Ciccarelli M; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
De Simone G; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
Mazza B; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
Barone A; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
Vellucci L; Section of Psychiatry, Laboratory of Translational and Molecular Psychiatry and Unit of Treatment-Resistant Psychosis, Department of Neuroscience, Reproductive Sciences and Dentistry, University Medical School of Naples 'Federico II', 80131 Naples, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 21; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 21.
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Schizophrenia*/drug therapy
Humans ; Dopamine/therapeutic use ; Schizophrenia, Treatment-Resistant ; beta-Arrestins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia.
Autorzy:
Schulmann A; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA. .
Marenco S; Human Brain Collection Core, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
Vawter MP; Functional Genomics Laboratory, Department of Psychiatry & Human Behavior, University of California, Irvine, Irvine, CA, USA.
Akula N; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
Limon A; Department of Neurology, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Mandal A; Human Brain Collection Core, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
Auluck PK; Human Brain Collection Core, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
Patel Y; Human Brain Collection Core, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
Lipska BK; Human Brain Collection Core, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA.
McMahon FJ; Human Genetics Branch, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA. .
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Źródło:
Translational psychiatry [Transl Psychiatry] 2023 Mar 17; Vol. 13 (1), pp. 93. Date of Electronic Publication: 2023 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:
Schizophrenia*/drug therapy
Schizophrenia*/genetics
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Humans ; Brain/metabolism ; Prefrontal Cortex/metabolism ; Transcriptome
Czasopismo naukowe
Szczegóły
Tytuł:
The efficacy of lumateperone on symptoms of depression in bipolar I and bipolar II disorder: Secondary and post hoc analyses.
Autorzy:
McIntyre RS; University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Department of Pharmacology, University of Toronto, Toronto, ON, Canada. Electronic address: .
Durgam S; Intra-Cellular Therapies, Inc, New York, NY, USA.
Kozauer SG; Intra-Cellular Therapies, Inc, New York, NY, USA.
Chen R; Intra-Cellular Therapies, Inc, New York, NY, USA.
Huo J; Intra-Cellular Therapies, Inc, New York, NY, USA.
Davis RE; Intra-Cellular Therapies, Inc, New York, NY, USA.
Cutler AJ; Department of Psychiatry, SUNY Upstate Medical University, Lakewood Ranch, FL, USA.
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Źródło:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology [Eur Neuropsychopharmacol] 2023 Mar; Vol. 68, pp. 78-88. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bipolar Disorder*/diagnosis
Depressive Disorder, Major*/drug therapy
Antipsychotic Agents*/therapeutic use
Humans ; Depression/drug therapy ; Anhedonia ; Double-Blind Method ; Treatment Outcome
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy of blonanserin transdermal patch on terminal delirium in patients with respiratory diseases.
Autorzy:
Ando K; Department of Respiratory Internal Medicine, Meguro K Home Clinic, 4-5-1-AceBIdg. Nakameguro, Meguro-ku, Tokyo, 153-0061, Japan. Electronic address: .
Suzuki A; Department of Respiratory Internal Medicine, Meguro K Home Clinic, 4-5-1-AceBIdg. Nakameguro, Meguro-ku, Tokyo, 153-0061, Japan.
Yoshida H; Data Seed Inc., 6-6-1-408, Niijyuku, Katsushika-ku, Tokyo, 125-0051, Japan.
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Źródło:
Respiratory investigation [Respir Investig] 2023 Mar; Vol. 61 (2), pp. 240-246. Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antipsychotic Agents*/pharmacology
Antipsychotic Agents*/therapeutic use
Delirium*/drug therapy
Humans ; Haloperidol/therapeutic use ; Transdermal Patch ; Retrospective Studies ; Dyspnea
Czasopismo naukowe
Szczegóły
Tytuł:
P50 sensory gating, cognitive deficits and depressive symptoms in first-episode antipsychotics-naïve schizophrenia.
Autorzy:
Li S; Institute of Mental Health, Tianjin Anding Hospital, Mental health center of Tianjin Medical University, Tianjin, China.
Yu B; Institute of Applied Psychology, Tianjin University, Tianjin, China; Academy of Medical Engineering and Translational Medicine, Tianjin University, China.
Wang D; CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Xia L; CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Wang L; CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
Chen D; Beijing HuiLongGuan Hospital, Peking University HuiLongGuan Clinical Medical School, Beijing, China.
Xiu M; Beijing HuiLongGuan Hospital, Peking University HuiLongGuan Clinical Medical School, Beijing, China.
Zhang XY; CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China. Electronic address: .
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Źródło:
Journal of affective disorders [J Affect Disord] 2023 Mar 01; Vol. 324, pp. 153-161. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antipsychotic Agents*/therapeutic use
Antipsychotic Agents*/pharmacology
Schizophrenia*/complications
Schizophrenia*/drug therapy
Cognitive Dysfunction*/etiology
Humans ; Depression ; Sensory Gating/physiology ; Cognition ; Electroencephalography ; Evoked Potentials, Auditory/physiology
Czasopismo naukowe
Szczegóły
Tytuł:
Clinicodemographic correlates of psychotic features in bipolar disorder - a multicenter study in China.
Autorzy:
Zhang ZF; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Huang J; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Zhu XQ; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Yu X; Peking University Institute of Mental Health (the sixth Hospital) & National Clinical Research Center for Mental Disorders & the key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China.
Yang HC; Division of Mood Disorders, Shenzhen Mental Health Centre, Guangdong Province, Shenzhen, China.
Xu XF; Department of Psychiatry, the First Affiliated Hospital of Kunming Medical University, Yunnan Province, Kunming, China.
Fang YR; Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tan QR; Department of Psychiatry, Xijing Hospital, Fourth Military Medical University, Shaanxi Province, Xi'an, China.
Li HC; The Second Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang Province, Hangzhou, China.
Wang G; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.; Advanced Innovation Center for Human Brain Protection, Capital Medical University, 100069, Beijing, China.
Zhang L; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China. .; Advanced Innovation Center for Human Brain Protection, Capital Medical University, 100069, Beijing, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 May 24; Vol. 23 (1), pp. 365. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bipolar Disorder*/diagnosis
Bipolar Disorder*/epidemiology
Depressive Disorder, Major*
Antipsychotic Agents*/therapeutic use
Humans ; Affect ; Anticonvulsants ; Antimanic Agents ; China/epidemiology
Czasopismo naukowe
Szczegóły
Tytuł:
Enhanced L-β-Aminoisobutyric Acid Is Involved in the Pathophysiology of Effectiveness for Treatment-Resistant Schizophrenia and Adverse Reactions of Clozapine.
Autorzy:
Fukuyama K; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu 514-8507, Japan.
Motomura E; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu 514-8507, Japan.
Okada M; Department of Neuropsychiatry, Division of Neuroscience, Graduate School of Medicine, Mie University, Tsu 514-8507, Japan.
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Źródło:
Biomolecules [Biomolecules] 2023 May 19; Vol. 13 (5). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Clozapine*/adverse effects
Antipsychotic Agents*/adverse effects
Schizophrenia*/metabolism
Receptors, Metabotropic Glutamate*/metabolism
Rats ; Animals ; Dizocilpine Maleate/pharmacology ; Glutamic Acid/metabolism ; Schizophrenia, Treatment-Resistant ; Rats, Sprague-Dawley ; Prefrontal Cortex/metabolism ; Receptors, Glutamate ; Receptors, GABA-A/metabolism ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Prescription characteristics associated with drug overdose risk among adults prescribed benzodiazepines: a cohort study.
Autorzy:
Maust DT; Injury Prevention Center, University of Michigan, Ann Arbor, MI, 48109, USA. .; Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA. .; Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA. .; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA. .
Bohnert ASB; Injury Prevention Center, University of Michigan, Ann Arbor, MI, 48109, USA.; Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Strominger J; Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Goldstick JE; Injury Prevention Center, University of Michigan, Ann Arbor, MI, 48109, USA.; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.; Department of Emergency Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
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Źródło:
BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2023 May 19; Vol. 24 (1), pp. 34. Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Antipsychotic Agents*/therapeutic use
Drug Overdose*/epidemiology
Drug Overdose*/drug therapy
Humans ; Adult ; Aged ; United States/epidemiology ; Cohort Studies ; Benzodiazepines/adverse effects ; Analgesics, Opioid/adverse effects ; Retrospective Studies ; Anticonvulsants/therapeutic use ; Medicare ; Prescriptions
Czasopismo naukowe
Szczegóły
Tytuł:
Human Hemoglobin and Antipsychotics Clozapine, Ziprasidone and Sertindole: Friends or Foes?
Autorzy:
Platanić Arizanović L; University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
Gligorijević N; Institute of Chemistry, Technology, and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, Serbia.
Cvijetić I; University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
Mijatović A; Faculty of Mining and Geology, University of Belgrade, Đušina 7, 11000 Belgrade, Serbia.
Ristivojević MK; University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
Minić S; University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
Kokić AN; Institute for Biological Research 'Siniša Stanković', National Institute of the Republic of Serbia, University of Belgrade, Bulevar despota Stefana 142, 11000 Belgrade, Serbia.
Miljević Č; Institute of Mental Health, Palmotićeva 37, 11000 Belgrade, Serbia.
Nikolić M; University of Belgrade-Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 17; Vol. 24 (10). Date of Electronic Publication: 2023 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Antipsychotic Agents*/pharmacology
Clozapine*/pharmacology
Humans ; Molecular Docking Simulation ; Olanzapine ; Benzodiazepines
Czasopismo naukowe
Szczegóły
Tytuł:
Genetic Predictors of Antipsychotic Efflux Impairment via Blood-Brain Barrier: Role of Transport Proteins.
Autorzy:
Nasyrova RF; Institute of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, Saint-Petersburg 192019, Russia.; International Centre for Education and Research in Neuropsychiatry, Samara State Medical University, Samara 443016, Russia.
Shnayder NA; Institute of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, Saint-Petersburg 192019, Russia.; Shared Core Facilities 'Molecular and Cell Technologies', V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia.
Osipova SM; Institute of Personalized Psychiatry and Neurology, V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, Saint-Petersburg 192019, Russia.
Khasanova AK; Department of Psychiatry, Russian Medical Academy for Continual Professional Education, Moscow 125993, Russia.
Efremov IS; Department of Psychiatry and Addiction, Bashkir State Medical University, Ufa 450008, Russia.
Al-Zamil M; Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples' Friendship University of Russia, Moscow 117198, Russia.
Petrova MM; Shared Core Facilities 'Molecular and Cell Technologies', V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia.
Narodova EA; Shared Core Facilities 'Molecular and Cell Technologies', V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk 660022, Russia.
Garganeeva NP; Department of General Medical Practice and Outpatient Therapy, Siberian State Medical University, Tomsk 634050, Russia.
Shipulin GA; Centre for Strategic Planning and Management of Biomedical Health Risks Management, Moscow 119121, Russia.
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Źródło:
Genes [Genes (Basel)] 2023 May 15; Vol. 14 (5). Date of Electronic Publication: 2023 May 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Multidrug Resistance-Associated Proteins*/metabolism
Antipsychotic Agents*/adverse effects
United States ; Humans ; Blood-Brain Barrier/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Neoplasm Proteins/metabolism ; ATP-Binding Cassette Transporters/genetics ; Biomarkers/metabolism
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 51953

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