Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Antiviral Agents"" wg kryterium: Temat


Tytuł:
Natural Product-Derived Phytochemicals for Influenza A Virus (H1N1) Prevention and Treatment.
Autorzy:
Li R; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.
Han Q; Foreign Language Education Department, Zhengzhou Shuqing Medical College, Zhengzhou 450064, China.
Li X; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.
Liu X; Co-Construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan & Education Ministry of China, Zhengzhou 450003, China.; Academy of Chinese Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, 450003, China.
Jiao W; College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450003, China.; Department of Pharmacy, Henan Province Hospital of Traditional Chinese Medicine, Zhengzhou 450046, China.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 17; Vol. 29 (10). Date of Electronic Publication: 2024 May 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Influenza A Virus, H1N1 Subtype*/drug effects
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Antiviral Agents*/chemistry
Phytochemicals*/therapeutic use
Phytochemicals*/pharmacology
Phytochemicals*/chemistry
Biological Products*/pharmacology
Biological Products*/chemistry
Biological Products*/therapeutic use
Influenza, Human*/drug therapy
Influenza, Human*/prevention & control
Humans ; Animals ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Flavonoids/therapeutic use
Czasopismo naukowe
Tytuł:
Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections.
Autorzy:
Hurwitz SJ; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
De R; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
LeCher JC; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Downs-Bowen JA; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Goh SL; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Zandi K; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
McBrayer T; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Amblard F; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Patel D; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Kohler JJ; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Bhasin M; Center for Cystic Fibrosis & Airways Disease Research, Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis and Sleep, Emory University and Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.
Dobosh BS; Center for Cystic Fibrosis & Airways Disease Research, Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis and Sleep, Emory University and Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.
Sukhatme V; Morningside Center for Innovative and Affordable Medicine, Departments of Medicine and Hematology and Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Tirouvanziam RM; Center for Cystic Fibrosis & Airways Disease Research, Division of Pulmonary, Allergy & Immunology, Cystic Fibrosis and Sleep, Emory University and Children's Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA 30322, USA.
Schinazi RF; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 1760 Haygood Drive, Atlanta, GA 30322, USA.
Pokaż więcej
Źródło:
Viruses [Viruses] 2024 Apr 22; Vol. 16 (4). Date of Electronic Publication: 2024 Apr 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
Drug Repositioning*
SARS-CoV-2*/drug effects
COVID-19 Drug Treatment*
Humans ; Chlorocebus aethiops ; Vero Cells ; Caco-2 Cells ; Animals ; COVID-19/virology
Czasopismo naukowe
Tytuł:
The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.
Autorzy:
Starvaggi J; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Previti S; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Zappalà M; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Ettari R; Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 16; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
Dengue*/drug therapy
Dengue*/virology
Protease Inhibitors*/therapeutic use
Protease Inhibitors*/pharmacology
Protease Inhibitors*/chemistry
Zika Virus Infection*/drug therapy
Zika Virus Infection*/virology
Animals ; Humans ; DEAD-box RNA Helicases ; Dengue Virus/drug effects ; Nucleoside-Triphosphatase ; Serine Endopeptidases/metabolism ; Serine Endopeptidases/chemistry ; Viral Nonstructural Proteins/antagonists & inhibitors ; Viral Nonstructural Proteins/metabolism ; Viral Nonstructural Proteins/chemistry ; Viral Proteases ; Zika Virus/drug effects ; Zika Virus/enzymology
Czasopismo naukowe
Tytuł:
Structural, dynamic behaviour, in-vitro and computational investigations of Schiff's bases of 1,3-diphenyl urea derivatives against SARS-CoV-2 spike protein.
Autorzy:
Ullah S; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman.
Ullah A; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman.
Waqas M; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman.
Halim SA; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman.
Pasha AR; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman.; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, 60800, Pakistan. .
Mali SN; School of Pharmacy, D.Y. Patil University (Deemed to be University), Sector 7, Nerul, Navi Mumbai, 400706, India.
Jawarkar RD; Department of Medicinal Chemistry and Drug Discovery, Dr. Rajendra Gode Institute of Pharmacy, University Mardi Road, Amravati, 444603, India.
Khan A; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman. .
Khalid A; Substance Abuse and Toxicology Research Center, Jazan University, P.O. Box: 114, 45142, Jazan, Saudi Arabia.
Abdalla AN; Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, 21955, Makkah, Saudi Arabia.
Kashtoh H; Department of Biotechnology, Yeungnam University, Gyeongsan, 38541, Gyeongbuk, Republic of Korea. hamdy_.
Al-Harrasi A; Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616, Nizwa, Sultanate of Oman. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2024 Jun 01; Vol. 14 (1), pp. 12588. Date of Electronic Publication: 2024 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/metabolism
Spike Glycoprotein, Coronavirus*/chemistry
Schiff Bases*/chemistry
Schiff Bases*/pharmacology
SARS-CoV-2*/drug effects
Molecular Docking Simulation*
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Urea*/pharmacology
Urea*/analogs & derivatives
Urea*/chemistry
Molecular Dynamics Simulation*
Humans ; COVID-19 Drug Treatment ; COVID-19/virology
Czasopismo naukowe
Tytuł:
Sporadic Occurrence of Ensitrelvir-Resistant SARS-CoV-2, Japan.
Autorzy:
Doi A
Ota M
Saito M
Matsuyama S
Pokaż więcej
Źródło:
Emerging infectious diseases [Emerg Infect Dis] 2024 Jun; Vol. 30 (6), pp. 1289-1291. Date of Electronic Publication: 2024 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/epidemiology
COVID-19*/virology
Drug Resistance, Viral*/genetics
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
Mutation*
Humans ; Japan/epidemiology ; Male ; Female ; Middle Aged ; Aged ; Adult ; Viral Nonstructural Proteins/genetics ; COVID-19 Drug Treatment ; Indazoles ; Triazines ; Triazoles
Czasopismo naukowe
Tytuł:
Computational Screening Using a Combination of Ligand-Based Machine Learning and Molecular Docking Methods for the Repurposing of Antivirals Targeting the SARS-CoV-2 Main Protease.
Autorzy:
Yuda GPWC; Laboratory of Macromolecular Engineering, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada Sekip Utara II, 55281, Yogyakarta, Indonesia.
Hanif N; Master Student of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, 06100, Turkey.
Hermawan A; Laboratory of Macromolecular Engineering, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada Sekip Utara II, 55281, Yogyakarta, Indonesia. adam_.; Laboratory of Advanced Pharmaceutical Sciences. APSLC Building, Faculty of Pharmacy, Universitas Gadjah Mada Sekip Utara II, 55281, Yogyakarta, Indonesia. adam_.
Pokaż więcej
Źródło:
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences [Daru] 2024 Jun; Vol. 32 (1), pp. 47-65. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Docking Simulation*
Drug Repositioning*
Machine Learning*
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Coronavirus 3C Proteases*/antagonists & inhibitors
Coronavirus 3C Proteases*/chemistry
Coronavirus 3C Proteases*/metabolism
COVID-19 Drug Treatment*
Ligands ; Humans ; Drug Discovery/methods ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; Proline/analogs & derivatives ; Proline/chemistry ; Proline/pharmacology
Czasopismo naukowe
Tytuł:
Harmol used for the treatment of herpes simplex virus induced keratitis.
Autorzy:
Xu H; Department of Ophthalmology, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Zhou N; Department of Ophthalmology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, 22# Hankou Road, Nanjing, Jiangsu, 210093, China.
Huang Z; Department of Ophthalmology, Jinling Hospital, Nanjing Medical University, Nanjing, Jiangsu, China. .
Wu J; Medical School of Nanjing University, 22# Hankou Road, Nanjing, 210093, Jiangsu Province, China. .
Qian Y; Department of Caries and Endodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, 30# Zhongyang Road, Xuanwu District, Nanjing, Jiangsu, 210008, China. qian_.
Pokaż więcej
Źródło:
Virology journal [Virol J] 2024 May 27; Vol. 21 (1), pp. 118. Date of Electronic Publication: 2024 May 27.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Keratitis, Herpetic*/drug therapy
Keratitis, Herpetic*/virology
Herpesvirus 1, Human*/drug effects
Herpesvirus 1, Human*/physiology
Virus Replication*/drug effects
Disease Models, Animal*
Animals ; Mice ; Acyclovir/pharmacology ; Acyclovir/therapeutic use ; Cornea/virology ; Cornea/drug effects ; Cornea/pathology ; Chlorocebus aethiops ; Humans ; Female ; Vero Cells ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł:
Inhibitory effects of algal polysaccharide extract from Cladophora spp. against herpes simplex virus infection.
Autorzy:
Srisai P; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Suriyaprom S; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.; Office of Research Administration, Chiang Mai University, Chiang Mai, 50200, Thailand.; Natural Extracts and Innovative Products for Alternative Healthcare Research Group, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Panya A; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.; Natural Extracts and Innovative Products for Alternative Healthcare Research Group, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Pekkoh J; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Tragoolpua Y; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Natural Extracts and Innovative Products for Alternative Healthcare Research Group, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2024 May 24; Vol. 14 (1), pp. 11914. Date of Electronic Publication: 2024 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Polysaccharides*/pharmacology
Polysaccharides*/chemistry
Polysaccharides*/isolation & purification
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Chlorophyta*/chemistry
Herpesvirus 1, Human*/drug effects
Animals ; Chlorocebus aethiops ; Vero Cells ; Herpes Simplex/drug therapy ; Herpes Simplex/virology ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Herpesvirus 2, Human/drug effects
Czasopismo naukowe
Tytuł:
Synthesis of Fluorinated Nucleosides/Nucleotides and Their Antiviral Properties.
Autorzy:
Kothapalli Y; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.
Jones RA; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.
Chu CK; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.
Singh US; Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 19; Vol. 29 (10). Date of Electronic Publication: 2024 May 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Antiviral Agents*/chemical synthesis
Halogenation*
Nucleosides*/chemistry
Nucleosides*/chemical synthesis
Nucleosides*/pharmacology
Nucleotides*/chemistry
Nucleotides*/pharmacology
Nucleotides*/chemical synthesis
Humans ; Fluorine/chemistry ; Clinical Trials as Topic
Czasopismo naukowe
Tytuł:
Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16.
Autorzy:
Wu K; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Guo Y; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Xu T; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Sun Yat-Sen University, Shenzhen 518107, China.
Huang W; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Guo D; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Sun Yat-Sen University, Shenzhen 518107, China.; Guangzhou Laboratory, Bio-Island, Guangzhou 510320, China.
Cao L; Centre for Infection and Immunity Studies (CIIS), School of Medicine, Sun Yat-Sen University, Shenzhen 518107, China.
Lei J; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 15; Vol. 29 (10). Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Viral Nonstructural Proteins*/antagonists & inhibitors
Viral Nonstructural Proteins*/metabolism
Viral Nonstructural Proteins*/chemistry
Methyltransferases*/antagonists & inhibitors
Methyltransferases*/metabolism
Methyltransferases*/chemistry
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Molecular Dynamics Simulation*
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/chemistry
Humans ; Molecular Docking Simulation ; Drug Evaluation, Preclinical ; COVID-19 Drug Treatment ; COVID-19/virology ; Binding Sites ; Exoribonucleases
Czasopismo naukowe
Tytuł:
Development of a Fluorescent Assay and Imidazole-Containing Inhibitors by Targeting SARS-CoV-2 Nsp13 Helicase.
Autorzy:
Zhang C; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Yu J; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Deng M; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Zhang Q; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Jin F; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Chen L; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Li Y; School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China.
He B; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 14; Vol. 29 (10). Date of Electronic Publication: 2024 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Imidazoles*/chemistry
Imidazoles*/pharmacology
SARS-CoV-2*/enzymology
SARS-CoV-2*/drug effects
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Molecular Docking Simulation*
Viral Nonstructural Proteins*/antagonists & inhibitors
Viral Nonstructural Proteins*/metabolism
Viral Nonstructural Proteins*/chemistry
Humans ; COVID-19 Drug Treatment ; RNA Helicases/antagonists & inhibitors ; RNA Helicases/metabolism ; RNA Helicases/chemistry ; Fluorescent Dyes/chemistry ; Methyltransferases
Czasopismo naukowe
Tytuł:
A Reliable Multifaceted Solution against Foodborne Viral Infections: The Case of RiLK1 Decapeptide.
Autorzy:
Galatola E; Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), 80131 Naples, Italy.
Agrillo B; Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), 80131 Naples, Italy.
Gogliettino M; Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), 80131 Naples, Italy.
Palmieri G; Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), 80131 Naples, Italy.; Materias Srl, 80146 Naples, Italy.
Maccaroni S; National Reference Laboratory for Foodborne Viruses, Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Vicenza T; National Reference Laboratory for Foodborne Viruses, Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Proroga YTR; Department of Food Microbiology, Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Portici, Italy.
Mancusi A; Department of Food Microbiology, Istituto Zooprofilattico Sperimentale del Mezzogiorno, 80055 Portici, Italy.
Di Pasquale S; National Reference Laboratory for Foodborne Viruses, Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Suffredini E; National Reference Laboratory for Foodborne Viruses, Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Cozzi L; National Reference Laboratory for Foodborne Viruses, Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 14; Vol. 29 (10). Date of Electronic Publication: 2024 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Foodborne Diseases*/prevention & control
Foodborne Diseases*/drug therapy
Foodborne Diseases*/virology
Norovirus*/drug effects
Animals ; Humans ; Mice ; Antimicrobial Peptides/pharmacology ; Antimicrobial Peptides/chemistry ; Hepatitis A virus/drug effects ; Virus Diseases/drug therapy ; Microbial Sensitivity Tests
Czasopismo naukowe
Tytuł:
Remission of HPV-Related Diseases by Antivirals for Herpesvirus: Clinical Cases and a Literature Review.
Autorzy:
Balestrieri M; Gynaecology and Diagnostic Colposcopy Clinic, Via Enea, 23, 00181 Rome, Italy.
Chiantore MV; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases (EVOR) Unit, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Garbuglia AR; Laboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani, IRCCS, Via Portuense, 292, 00149 Rome, Italy.
Carnovale-Scalzo C; Histopathology Laboratory, Ospedale San Carlo di Nancy, GVM Care and Research, Via Aurelia, 275, 00165 Rome, Italy.
Falcucci S; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases (EVOR) Unit, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Di Bonito P; Department of Infectious Diseases, Viral Hepatitis and Oncovirus and Retrovirus Diseases (EVOR) Unit, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Pokaż więcej
Źródło:
Viruses [Viruses] 2024 May 10; Vol. 16 (5). Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
Papillomavirus Infections*/drug therapy
Papillomavirus Infections*/virology
Adult ; Female ; Humans ; Male ; Acyclovir/therapeutic use ; Acyclovir/pharmacology ; Treatment Outcome ; Valacyclovir/therapeutic use
Czasopismo naukowe
Tytuł:
Pseudovirus-Based Systems for Screening Natural Antiviral Agents: A Comprehensive Review.
Autorzy:
Trischitta P; Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.; Department of Chemistry, Biology, and Biotechnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
Tamburello MP; Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Venuti A; International Agency for Research on Cancer (IARC), World Health Organization, 69366 Lyon, CEDEX 07, France.
Pennisi R; Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 10; Vol. 25 (10). Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Virus Internalization*/drug effects
SARS-CoV-2*/drug effects
Biological Products*/pharmacology
Biological Products*/chemistry
Biological Products*/therapeutic use
Humans ; COVID-19 Drug Treatment ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Drug Repositioning/methods ; Spike Glycoprotein, Coronavirus/metabolism ; Spike Glycoprotein, Coronavirus/antagonists & inhibitors ; Spike Glycoprotein, Coronavirus/chemistry ; Drug Evaluation, Preclinical/methods
Czasopismo naukowe
Tytuł:
N -Heterocycles as Promising Antiviral Agents: A Comprehensive Overview.
Autorzy:
Ahmad G; Department of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Sohail M; Department of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Bilal M; School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
Rasool N; Department of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Qamar MU; Institute of Microbiology, Faculty of Life Sciences, Government College University, Faisalabad 38000, Pakistan.; Division of Infectious Diseases, Geneva University Hospitals, 1205 Geneva, Switzerland.; Department of Microbiology and Molecular Medicine, University of Geneva, 1205 Geneva, Switzerland.
Ciurea C; Faculty of Medicine, Transilvania University of Brasov, 500036 Brasov, Romania.
Marceanu LG; Faculty of Medicine, Transilvania University of Brasov, 500036 Brasov, Romania.
Misarca C; Faculty of Medicine, Transilvania University of Brasov, 500036 Brasov, Romania.
Pokaż więcej
Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 10; Vol. 29 (10). Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Antiviral Agents*/therapeutic use
Heterocyclic Compounds*/pharmacology
Heterocyclic Compounds*/chemistry
Humans ; Virus Replication/drug effects ; Structure-Activity Relationship ; Viruses/drug effects ; Virus Diseases/drug therapy ; Animals
Czasopismo naukowe
Tytuł:
Predicting drug-Protein interaction with deep learning framework for molecular graphs and sequences: Potential candidates against SAR-CoV-2.
Autorzy:
Du W; Department of Dermatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Zhao L; Shenzhen Health Development Research and Data Management Center, Shenzhen, China.
Wu R; Department of Dermatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huang B; School of Finance, Shanghai University of Finance and Economics, Shanghai, China.
Liu S; Department of Cosmetic and Plastic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Liu Y; Department of Cosmetic and Plastic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Huang H; Department of Dermatology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shi G; Department of Cosmetic and Plastic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2024 May 10; Vol. 19 (5), pp. e0299696. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
SARS-CoV-2*/drug effects
SARS-CoV-2*/metabolism
SARS-CoV-2*/genetics
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19 Drug Treatment*
Humans ; Coronavirus 3C Proteases/metabolism ; Coronavirus 3C Proteases/antagonists & inhibitors ; Protein Binding ; COVID-19/virology ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Hepatitis B: Model Systems and Therapeutic Approaches.
Autorzy:
Yu X; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Gao Y; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhang X; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ji L; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fang M; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li M; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Gao Y; Laboratory of Cellular Immunity, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Department of Hepatopathy, Shuguang Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Institute of Infectious Diseases of Integrated Traditional Chinese and Western Medicine, Shanghai, China.
Pokaż więcej
Źródło:
Journal of immunology research [J Immunol Res] 2024 May 07; Vol. 2024, pp. 4722047. Date of Electronic Publication: 2024 May 07 (Print Publication: 2024).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hepatitis B virus*/physiology
Hepatitis B virus*/drug effects
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
Disease Models, Animal*
Hepatitis B*/drug therapy
Hepatitis B*/virology
Hepatitis B*/immunology
Virus Replication*/drug effects
Humans ; Animals ; Mice ; Hepatocytes/virology
Czasopismo naukowe
Tytuł:
Binding Activity Classification of Anti-SARS-CoV-2 Molecules using Deep Learning Across Multiple Assays
Autorzy:
Yamasan BE; Department of Biophysics, Trakya University Faculty of Medicine, Edirne, Türkiye
Korkmaz S; Department of Biostatistics and Medical Informatics, Trakya University Faculty of Medicine, Edirne, Türkiye
Pokaż więcej
Źródło:
Balkan medical journal [Balkan Med J] 2024 May 03; Vol. 41 (3), pp. 186-192. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Deep Learning*
SARS-CoV-2*/drug effects
Antiviral Agents*/therapeutic use
Antiviral Agents*/pharmacology
COVID-19*
Humans ; Angiotensin-Converting Enzyme 2/metabolism ; COVID-19 Drug Treatment ; Spike Glycoprotein, Coronavirus/metabolism ; Biological Assay/methods
Czasopismo naukowe
Tytuł:
In Vitro Effect of 9,9'-Norharmane Dimer against Herpes Simplex Viruses.
Autorzy:
Gonzalez MM; Instituto Tecnológico de Chascomús (CONICET-UNSAM), Av. Intendente Marino Km 8.2, CC 164 (B7130IWA), Chascomús 7130, Argentina.; Escuela de Bio y Nanotecnologías (UNSAM), San Martín 1650, Argentina.
Vizoso-Pinto MG; Max von Pettenkofer Institute, Virology, National Reference Center for Retroviruses, Faculty of Medicine, LMU, D-80336 Munich, Germany.; Instituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, San Miguel de Tucumán 4000, Argentina.; Laboratorio Central de Cs. Básicas, Facultad de Medicina, Universidad Nacional de Tucumán, Tucumán 4000, Argentina.
Erra-Balsells R; Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón II, 3er P., Ciudad Universitaria, Buenos Aires 1428, Argentina.; Centro de Investigación en Hidratos de Carbono (CIHIDECAR), CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Naturales Pabellón II, 3er P. Ciudad Universitaria, Buenos Aires 1428, Argentina.
Gensch T; Institute of Biological Information Processing 1 (IBI-1; Molecular and Cellular Physiology), Forschungszentrum Jülich, Wilhelm-Jonen-Straße, 52428 Jülich, Germany.
Cabrerizo FM; Instituto Tecnológico de Chascomús (CONICET-UNSAM), Av. Intendente Marino Km 8.2, CC 164 (B7130IWA), Chascomús 7130, Argentina.; Escuela de Bio y Nanotecnologías (UNSAM), San Martín 1650, Argentina.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 02; Vol. 25 (9). Date of Electronic Publication: 2024 May 02.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Chlorocebus aethiops ; Humans ; Vero Cells ; Animals ; Simplexvirus/drug effects ; Simplexvirus/physiology ; Herpes Simplex/drug therapy ; Herpes Simplex/virology ; Carbolines/pharmacology ; Carbolines/chemistry ; Herpesvirus 1, Human/drug effects ; Herpesvirus 1, Human/physiology ; Harmine/pharmacology ; Harmine/chemistry ; Harmine/analogs & derivatives
Czasopismo naukowe
Tytuł:
Predicting lung exposure of intramuscular niclosamide as an antiviral agent: Power-law based pharmacokinetic modeling.
Autorzy:
Kim T; Life Science Institute, Daewoong Pharmaceutical, Yongin, South Korea.
Jung W; College of Pharmacy, Chungnam National University, Daejeon, South Korea.
Cho S; Life Science Institute, Daewoong Pharmaceutical, Yongin, South Korea.
Kim G; Life Science Institute, Daewoong Pharmaceutical, Yongin, South Korea.
Yun HY; College of Pharmacy, Chungnam National University, Daejeon, South Korea.; Department of Bio-AI Convergence, Chungnam National University, Daejeon, South Korea.
Chae JW; College of Pharmacy, Chungnam National University, Daejeon, South Korea.; Department of Bio-AI Convergence, Chungnam National University, Daejeon, South Korea.
Pokaż więcej
Źródło:
Clinical and translational science [Clin Transl Sci] 2024 May; Vol. 17 (5), pp. e13833.
Typ publikacji:
Journal Article
MeSH Terms:
Niclosamide*/pharmacokinetics
Niclosamide*/administration & dosage
Antiviral Agents*/pharmacokinetics
Antiviral Agents*/administration & dosage
Lung*/metabolism
COVID-19 Drug Treatment*
Models, Biological*
Animals ; Injections, Intramuscular ; SARS-CoV-2 ; Cricetinae ; Dose-Response Relationship, Drug ; Male ; COVID-19
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies