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Wyszukujesz frazę ""Antiviral Agents"" wg kryterium: Temat


Tytuł:
Target-based drug design strategies to overcome resistance to antiviral agents: opportunities and challenges.
Autorzy:
Du S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China.
Hu X; Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao 266237, PR China.
Menéndez-Arias L; Centro de Biología Molecular 'Severo Ochoa' (Consejo Superior de Investigaciones Científicas & Universidad Autónoma de Madrid), Madrid, Spain. Electronic address: .
Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012 Jinan, Shandong, PR China. Electronic address: .
Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province, 44 West Culture Road, 250012 Jinan, Shandong, PR China. Electronic address: .
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Źródło:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2024 Mar; Vol. 73, pp. 101053. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Antiviral Agents*/metabolism
Drug Design*
Humans ; Drug Resistance, Viral/genetics ; Mutation
Czasopismo naukowe
Tytuł:
Effects of first-line nucleot(s)ide analogues on lipid profiles in patients with chronic hepatitis B: a network meta-analysis.
Autorzy:
Tong K; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chen M; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wang D; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Dai H; Department of Infectious Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Peng J; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhang J; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhou J; Department of Infectious Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chang Y; Department of Infectious Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Huang W; Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. wenxiang_.
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Źródło:
European journal of clinical pharmacology [Eur J Clin Pharmacol] 2024 Mar; Vol. 80 (3), pp. 335-354. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Meta-Analysis; Journal Article; Review
MeSH Terms:
Antiviral Agents*/therapeutic use
Hepatitis B, Chronic*/drug therapy
Humans ; Aged ; Cholesterol, LDL ; Network Meta-Analysis ; Tenofovir/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Developments in the chemistry and biology of 1,2,3-triazolyl-C-nucleosides.
Autorzy:
Nascimento SMRD; Biocatalysis and Organic Synthesis Group, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ferry A; CY Cergy Paris Université, CNRS, BioCIS, Cergy-Pontoise, France.; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Gallier F; CY Cergy Paris Université, CNRS, BioCIS, Cergy-Pontoise, France.; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Lubin-Germain N; CY Cergy Paris Université, CNRS, BioCIS, Cergy-Pontoise, France.; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Uziel J; CY Cergy Paris Université, CNRS, BioCIS, Cergy-Pontoise, France.; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Gonzales S; CY Cergy Paris Université, CNRS, BioCIS, Cergy-Pontoise, France.; Université Paris-Saclay, CNRS, BioCIS, Châtenay-Malabry, France.
Miranda LSME; Biocatalysis and Organic Synthesis Group, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
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Źródło:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Mar; Vol. 357 (3), pp. e2300580. Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Nucleosides*/pharmacology
Nucleosides*/chemistry
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Ribose/pharmacology ; Structure-Activity Relationship ; SARS-CoV-2 ; Cell Line, Tumor ; Biology
Czasopismo naukowe
Tytuł:
Targeting host-virus interactions: in silico analysis of the binding of human milk oligosaccharides to viral proteins involved in respiratory infections.
Autorzy:
Mahaboob Ali AA; Gene Therapy Laboratory, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore, 632 014, India.
Vishal A; Gene Therapy Laboratory, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore, 632 014, India.
Nelson EJR; Gene Therapy Laboratory, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore, 632 014, India. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 19; Vol. 14 (1), pp. 4111. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Influenza, Human*
Humans ; Viral Proteins ; Molecular Docking Simulation ; Milk, Human ; SARS-CoV-2 ; Oligosaccharides
Czasopismo naukowe
Tytuł:
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Autorzy:
Barton LS; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States. Electronic address: .
Callahan JF; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Cantizani J; GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
Concha NO; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Cotillo Torrejon I; GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
Goodwin NC; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Joshi-Pangu A; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Kiesow TJ; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
McAtee JJ; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Mellinger M; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Nixon CJ; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Padrón-Barthe L; GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
Patterson JR; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Pearson ND; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Pouliot JJ; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Rendina AR; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Buitrago Santanilla A; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Schneck JL; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Sanz O; GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain.
Thalji RK; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Ward P; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
Williams SP; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
King BW; GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA 19426, United States.
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Feb 15; Vol. 100, pp. 117618. Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Furans*/chemistry
Coronavirus Protease Inhibitors*/chemistry
Lactams ; Peptide Hydrolases ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry ; SARS-CoV-2
Czasopismo naukowe
Tytuł:
Biomolecular Condensates as Novel Antiviral Targets.
Autorzy:
Martin EW; Dewpoint Therapeutics, Boston, MA, USA.
Iserman C; Dewpoint Therapeutics GMBH, Dresden, Germany.
Olety B; Dewpoint Therapeutics, Boston, MA, USA.
Mitrea DM; Dewpoint Therapeutics, Boston, MA, USA.
Klein IA; Dewpoint Therapeutics, Boston, MA, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2024 Feb 15; Vol. 436 (4), pp. 168380. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Biomolecular Condensates*/drug effects
Virus Diseases*/drug therapy
Virus Diseases*/virology
Virus Replication*/drug effects
Humans ; Drug Discovery
Czasopismo naukowe
Tytuł:
An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.
Autorzy:
Shannon A; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Chazot A; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Feracci M; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Falcou C; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Fattorini V; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Selisko B; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Good S; ATEA Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA 02110, USA.
Moussa A; ATEA Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA 02110, USA.
Sommadossi JP; ATEA Pharmaceuticals, Inc., 225 Franklin St., Suite 2100, Boston, MA 02110, USA.
Ferron F; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.; European Virus Bioinformatics Center, Leutragraben 1, 07743 Jena, Germany.
Alvarez K; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.
Canard B; AFMB, CNRS, Aix-Marseille University, UMR 7257, Case 925, 163 Avenue de Luminy, 13288, Marseille Cedex 09, France.; European Virus Bioinformatics Center, Leutragraben 1, 07743 Jena, Germany.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Feb 09; Vol. 52 (3), pp. 1325-1340.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
COVID-19*/virology
Polyphosphates*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19 Drug Treatment*
Humans ; Exonucleases ; Nucleotides/metabolism ; Nucleotidyltransferases ; RNA, Viral/genetics ; Viral Nonstructural Proteins/metabolism ; Virus Replication/genetics ; Coronavirus RNA-Dependent RNA Polymerase/metabolism
Czasopismo naukowe
Tytuł:
Bakuchiol targets mitochondrial proteins, prohibitins and voltage-dependent anion channels: New insights into developing antiviral agents.
Autorzy:
Shoji M; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan. Electronic address: .
Esumi T; Institute of Pharmacognosy Attached to Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Masuda T; Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan; Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Tanaka N; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Okamoto R; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Sato H; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Watanabe M; Institute of Pharmacognosy Attached to Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Takahashi E; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Kido H; Division of Enzyme Chemistry, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Ohtsuki S; Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Kuzuhara T; Laboratory of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2024 Feb; Vol. 300 (2), pp. 105632. Date of Electronic Publication: 2024 Jan 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Influenza, Human*
Phenols*
Animals ; Dogs ; Humans ; Mitochondrial Proteins/metabolism ; Prohibitins ; Tandem Mass Spectrometry ; Voltage-Dependent Anion Channel 1 ; Voltage-Dependent Anion Channel 2/metabolism ; Voltage-Dependent Anion Channels ; Cell Line
Czasopismo naukowe
Tytuł:
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
Autorzy:
García-Rodríguez I; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Moreni G; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Capendale PE; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Mulder L; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Aknouch I; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; Viroclinics Xplore, Schaijk, the Netherlands.
Vieira de Sá R; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; UniQure Biopharma B.V., Department of Research & Development, Paasheuvelweg 25A, 1105, BE, Amsterdam, the Netherlands.
Johannesson N; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Freeze E; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
van Eijk H; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Koen G; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Wolthers KC; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Pajkrt D; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Sridhar A; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands.
Calitz C; Emma Children's Hospital, Department of Pediatric Infectious Diseases, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, Amsterdam Institute for Reproduction and Development, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands; OrganoVIR Labs, Department of Medical Microbiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam Institute for Infection and Immunity, University of Amsterdam, Meibergdreef 9, 1100, AZ, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Antiviral research [Antiviral Res] 2024 Feb; Vol. 222, pp. 105798. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Viruses*
Piperidines*
Quinazolinones*
Humans ; Microphysiological Systems ; SARS-CoV-2 ; Brain
Czasopismo naukowe
Tytuł:
Targeting cap1 RNA methyltransferases as an antiviral strategy.
Autorzy:
Tsukamoto Y; Institute of Cardiovascular Immunology, Medical Faculty, University Hospital Bonn, University of Bonn, Bonn, Germany.
Igarashi M; Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Hokkaido, Japan.
Kato H; Institute of Cardiovascular Immunology, Medical Faculty, University Hospital Bonn, University of Bonn, Bonn, Germany. Electronic address: .
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Źródło:
Cell chemical biology [Cell Chem Biol] 2024 Jan 18; Vol. 31 (1), pp. 86-99. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Methyltransferases*/antagonists & inhibitors
RNA Caps*/genetics
RNA Caps*/metabolism
RNA, Viral*/genetics
RNA, Viral*/metabolism
Drug Design*
Methylation ; RNA, Messenger/metabolism ; Humans
Czasopismo naukowe
Tytuł:
Design of MERS-CoV entry inhibitory short peptides based on helix-stabilizing strategies.
Autorzy:
Li J; College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, 26 Yuxiang Street, Shijiazhuang 050018, China; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
Li Q; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
Xia S; Key Laboratory of Medical Molecular Virology of MOE/MOH/CAMS, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, 131 Dong An Road, Shanghai 200032, China.
Tu J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
Zheng L; Key Laboratory of Structure-based Drug Design & Discovery of the Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wang Q; Key Laboratory of Medical Molecular Virology of MOE/MOH/CAMS, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, 131 Dong An Road, Shanghai 200032, China.
Jiang S; Key Laboratory of Medical Molecular Virology of MOE/MOH/CAMS, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, 131 Dong An Road, Shanghai 200032, China. Electronic address: .
Wang C; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jan 01; Vol. 97, pp. 129569. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Middle East Respiratory Syndrome Coronavirus*/drug effects
Peptides/chemistry ; Protein Conformation, alpha-Helical ; Lipopeptides/pharmacology ; Lipopeptides/therapeutic use
Czasopismo naukowe
Tytuł:
Prescriber perceptions of boxed warnings: A qualitative study.
Autorzy:
Ingersoll RN; Fors Marsh, Health Communication Research, Arlington, Virginia, USA.
Bui ET; Fors Marsh, Health Communication Research, Arlington, Virginia, USA.
Coleman B; Office of Program and Strategic Analysis (OPSA), Center for Drug Evaluation and Research (CDER), U.S. Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Zhou EH; Office of Surveillance and Epidemiology (OSE), Center for Drug Evaluation and Research (CDER), U.S. Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Eggers S; Office of Program and Strategic Analysis (OPSA), Center for Drug Evaluation and Research (CDER), U.S. Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
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Źródło:
Pharmacoepidemiology and drug safety [Pharmacoepidemiol Drug Saf] 2024 Mar; Vol. 33 (3), pp. e5766.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*
Hepatitis C, Chronic*/drug therapy
Female ; Humans ; United States ; Drug Labeling ; Qualitative Research ; United States Food and Drug Administration
Czasopismo naukowe
Tytuł:
Oseltamivir phosphate interaction with model membranes.
Autorzy:
Čelková A; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov10, 832 32 Bratislava, Slovakia.
Búcsi A; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov10, 832 32 Bratislava, Slovakia. Electronic address: .
Klacsová M; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov10, 832 32 Bratislava, Slovakia.
Fazekaš T; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov10, 832 32 Bratislava, Slovakia.
Martínez JC; ALBA Synchrotron, Cerdanyola del Vallés, 08290 Barcelona, Spain.
Uhríková D; Department of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov10, 832 32 Bratislava, Slovakia.
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Źródło:
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2024 Mar; Vol. 1866 (3), pp. 184273. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Oseltamivir*/chemistry
Oseltamivir*/pharmacology
Antiviral Agents*/pharmacology
Lipid Bilayers/chemistry ; Phospholipids ; Phosphates
Czasopismo naukowe
Tytuł:
Ser38-His93-Asn91 triad confers resistance of JFH1 HCV NS5A-Y93H variant to NS5A inhibitors.
Autorzy:
Lee WP; Department of Medical Research, Taipei Veterans General Hospital, Taiwan.; Institute of Biochemistry and Molecular Biology, School of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tsai KC; National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan.; The Ph.D. Program for Medical Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taiwan.
Liao SX; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taiwan.
Huang YH; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hou MC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Lan KH; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
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Źródło:
The FEBS journal [FEBS J] 2024 Mar; Vol. 291 (6), pp. 1264-1274. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Hepatitis C, Chronic*/drug therapy
Humans ; Genotype ; Hepacivirus/genetics ; Viral Nonstructural Proteins/genetics ; Drug Resistance, Viral/genetics
Czasopismo naukowe
Tytuł:
Development of an optimized, non-stem cell line for intranasal delivery of therapeutic cargo to the central nervous system.
Autorzy:
El-Ayoubi A; Molecular Neurooncology, Department of Vascular Neurology, Hertie Institute for Clinical Brain Research and Center Neurology, University Hospital of Tübingen, Germany.
Arakelyan A; Research Group of Bioinformatics, Institute of Molecular Biology NAS RA, Yerevan, Armenia.
Klawitter M; Molecular Neurooncology, Department of Vascular Neurology, Hertie Institute for Clinical Brain Research and Center Neurology, University Hospital of Tübingen, Germany.
Merk L; Molecular Neurooncology, Department of Vascular Neurology, Hertie Institute for Clinical Brain Research and Center Neurology, University Hospital of Tübingen, Germany.
Hakobyan S; Research Group of Bioinformatics, Institute of Molecular Biology NAS RA, Yerevan, Armenia.; Armenian Institute of Bioinformatics, Yerevan, Armenia.
Gonzalez-Menendez I; Institute for Pathology, Department of General and Molecular Pathology, University Hospital Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Germany.
Quintanilla Fend L; Institute for Pathology, Department of General and Molecular Pathology, University Hospital Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Germany.
Holm PS; Department of Urology, Klinikum rechts der Isar, Technical University of Munich, Germany.; Department of Oral and Maxillofacial Surgery, Medical University Innsbruck, Austria.; XVir Therapeutics GmbH, Munich, Germany.
Mikulits W; Center for Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Austria.
Schwab M; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Germany.; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Department of Pharmacy and Biochemistry, University of Tübingen, Germany.; Department of Clinical Pharmacology, University Hospital Tübingen, Germany.; Neuroscience Laboratory and Departments of Biochemistry and Clinical Pharmacology, Yerevan State Medical University, Armenia.
Danielyan L; Department of Pharmacy and Biochemistry, University of Tübingen, Germany.; Department of Clinical Pharmacology, University Hospital Tübingen, Germany.; Neuroscience Laboratory and Departments of Biochemistry and Clinical Pharmacology, Yerevan State Medical University, Armenia.
Naumann U; Molecular Neurooncology, Department of Vascular Neurology, Hertie Institute for Clinical Brain Research and Center Neurology, University Hospital of Tübingen, Germany.; Gene and RNA Therapy Center (GRTC), Faculty of Medicine University Tübingen, Germany.
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Źródło:
Molecular oncology [Mol Oncol] 2024 Mar; Vol. 18 (3), pp. 528-546. Date of Electronic Publication: 2023 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*
Genetic Therapy*
Mice ; Humans ; Animals ; Administration, Intranasal ; Cell Line ; Central Nervous System/metabolism ; Thymidine Kinase/genetics ; Thymidine Kinase/metabolism ; Thymidine Kinase/therapeutic use
Czasopismo naukowe
Tytuł:
Immunomodulatory effects of tenofovir disoproxil fumarate and entecavir in treating HBV infection.
Autorzy:
Yu X; Department of Infectious Diseases, Fujian Medical University Affiliated First Quanzhou Hospital, Quanzhou 362000, Fujian, China; Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Shanghai Institute of Infectious Diseases and Biosecurity, National Medical Center for Infectious Diseases, Huashan Hospital Affiliated to Fudan University. Shanghai, 200040, China.
Long J; Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Shanghai Institute of Infectious Diseases and Biosecurity, National Medical Center for Infectious Diseases, Huashan Hospital Affiliated to Fudan University. Shanghai, 200040, China; Department of Pharmacy, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
Xie Y; Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Shanghai Institute of Infectious Diseases and Biosecurity, National Medical Center for Infectious Diseases, Huashan Hospital Affiliated to Fudan University. Shanghai, 200040, China.
Zhang J; Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Shanghai Institute of Infectious Diseases and Biosecurity, National Medical Center for Infectious Diseases, Huashan Hospital Affiliated to Fudan University. Shanghai, 200040, China. Electronic address: .
Su Z; Department of Infectious Diseases, Fujian Medical University Affiliated First Quanzhou Hospital, Quanzhou 362000, Fujian, China. Electronic address: .
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Źródło:
Journal of hepatology [J Hepatol] 2024 Mar; Vol. 80 (3), pp. e123-e125. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Letter
MeSH Terms:
Hepatitis B virus*
Antiviral Agents*/therapeutic use
Guanine/*analogs & derivatives
Tenofovir/therapeutic use ; Guanine/therapeutic use ; Treatment Outcome
Opinia redakcyjna
Tytuł:
Ligand concentration determines antiviral efficacy of silica multivalent nanoparticles.
Autorzy:
Wang H; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland.
Xu X; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland.
Polla R; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland.
Silva PJ; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland.
Ong QK; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland.
Stellacci F; Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland; Global Health Institute, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, CH-1015 Lausanne, Switzerland. Electronic address: .
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Źródło:
Journal of colloid and interface science [J Colloid Interface Sci] 2024 Mar; Vol. 657, pp. 327-333. Date of Electronic Publication: 2023 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Nanoparticles*/chemistry
Humans ; Ligands ; Pandemics ; Herpesvirus 2, Human
Czasopismo naukowe
Tytuł:
In search of a 'good number': knowledge controversy and population estimates in the endgame of hepatitis C elimination.
Autorzy:
Rhodes T; London School of Hygiene & Tropical Medicine, London, UK .; University of New South Wales, Sydney, New South Wales, Australia.
Lancaster K; Goldsmiths University of London, London, UK.; University of New South Wales, Sydney, New South Wales, Australia.
Adams S; Deakin University, Burwood, Australia.
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Źródło:
BMJ global health [BMJ Glob Health] 2024 Feb 27; Vol. 9 (2). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/therapeutic use
Hepatitis C*/epidemiology
Hepatitis C*/prevention & control
Hepatitis C*/drug therapy
Humans ; Disease Eradication ; Australia/epidemiology ; Prevalence
Czasopismo naukowe
Tytuł:
Characteristics of patients with chronic hepatitis B infection in China: A retrospective claims database study.
Autorzy:
Meng X; GSK, Institute for Infectious Diseases and Public Health, Beijing, China.; Present address: Sinovac Biotech Co., Ltd, Clinical Research Department, Beijing, China.
Gillespie IA; GSK, Epidemiology, Stevenage, UK.
Dong J; GSK, Institute for Infectious Diseases and Public Health, Beijing, China.
Ning Y; School of Public Health, Hainan Medical University, Haikou, China.
Kendrick S; GSK, Hepatology, Stevenage, UK.
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Źródło:
Medicine [Medicine (Baltimore)] 2024 Feb 16; Vol. 103 (7), pp. e36645.
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Antiviral Agents*
Hepatitis B, Chronic*/drug therapy
Hepatitis B, Chronic*/epidemiology
Hepatitis B, Chronic*/complications
Humans ; Male ; Female ; Retrospective Studies ; Health Care Costs ; Liver Cirrhosis/complications ; Hepatitis B virus
Czasopismo naukowe
Tytuł:
Synthesis of 4 H -Pyrazolo[3,4- d ]pyrimidin-4-one Hydrazine Derivatives as a Potential Inhibitor for the Self-Assembly of TMV Particles.
Autorzy:
Wang Y; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Guo S; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Sun W; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Tu H; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Tang Y; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Xu Y; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Guo R; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Zhao Z; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Yang Z; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
Wu J; National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Feb 14; Vol. 72 (6), pp. 2879-2887. Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/chemistry
Tobacco Mosaic Virus*
Structure-Activity Relationship ; Molecular Docking Simulation ; Hydrazines/pharmacology
Czasopismo naukowe

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