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Tytuł:
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics.
Autorzy:
Borhani SG; Center for Advanced Sensor Technology, Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Levine MZ; Department of Chemical Engineering and Department of Bioengineering, Stanford University, Stanford, CA 94305-5025, USA.
Krumpe LH; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, MD 21702, USA; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Wilson J; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, MD 21702, USA.
Henrich CJ; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, MD 21702, USA; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
O'Keefe BR; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, MD 21702, USA; Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, MD 21702, USA.
Lo DC; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Sittampalam GS; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Godfrey AG; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Lunsford RD; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Mangalampalli V; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Tao D; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
LeClair CA; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, USA.
Thole AP; Center for Advanced Sensor Technology, Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Frey D; Center for Advanced Sensor Technology, Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Swartz J; Department of Chemical Engineering and Department of Bioengineering, Stanford University, Stanford, CA 94305-5025, USA.
Rao G; Center for Advanced Sensor Technology, Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA. Electronic address: .
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Źródło:
New biotechnology [N Biotechnol] 2023 Sep 25; Vol. 76, pp. 13-22. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19*
Humans ; Cell-Free System ; Pandemics/prevention & control ; SARS-CoV-2
Czasopismo naukowe
Szczegóły
Tytuł:
Meeting report: 36th International Conference on Antiviral Research in Lyon, France - March 13-17, 2023.
Autorzy:
Spengler JR; Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: .
Carter K; Evotec US, Princeton, NJ, USA.
Delang L; Laboratory of Virology and Chemotherapy, Mosquito Virology Team, KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Leuven, Belgium.
Durantel D; Centre International de Recherche en Infectiologie (CIRI), Inserm_U1111, CNRS_UMR5308, Université Claude Bernard Lyon 1, F-69007, Lyon, France.
Gowen BB; Institute for Antiviral Research and Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
Herrero LJ; The Institute for Glycomics, Griffith University, Southport, QLD, Australia.
Hurst B; Institute for Antiviral Research and Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA.
Janeba Z; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, Prague, Czech Republic.
Jordan R; Global Health Discovery & Translational Sciences, Bill & Melinda Gates Foundation, Seattle, WA, USA.
Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore; National Centre for Infectious Diseases, Singapore, Singapore.
Meier C; Organic Chemistry, Department of Chemistry, Faculty of Sciences, University of Hamburg, Hamburg, Germany.
Moffat J; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY, USA.
Rocha-Pereira J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Seley-Radtke KL; Department of Chemistry & Biochemistry, University of Maryland, Baltimore County, Baltimore, MD, USA.
Welch SR; Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Schang LM; Baker Institute and Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA.
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Źródło:
Antiviral research [Antiviral Res] 2023 Sep; Vol. 217, pp. 105678. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Congress; Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19*
Humans ; Iron-Dextran Complex ; Pandemics ; SARS-CoV-2
Czasopismo naukowe
Szczegóły
Tytuł:
Identification of a leucine-zipper motif in pUL51 essential for HCMV replication and potential target for antiviral development.
Autorzy:
Muller C; Univ. Limoges, INSERM, CHU Limoges, RESINFIT, U1092, F-87000, Limoges, France.
Alain S; Univ. Limoges, INSERM, CHU Limoges, RESINFIT, U1092, F-87000, Limoges, France; CHU Limoges, Laboratoire de Bactériologie-Virologie-Hygiène, National Reference Center for Herpesviruses (NRCHV), F-87000, Limoges, France.
Hantz S; Univ. Limoges, INSERM, CHU Limoges, RESINFIT, U1092, F-87000, Limoges, France; CHU Limoges, Laboratoire de Bactériologie-Virologie-Hygiène, National Reference Center for Herpesviruses (NRCHV), F-87000, Limoges, France. Electronic address: .
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Źródło:
Antiviral research [Antiviral Res] 2023 Sep; Vol. 217, pp. 105673. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leucine Zippers*
Virus Replication*/drug effects
Cytomegalovirus*/drug effects
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Viral Proteins*/antagonists & inhibitors
Viral Proteins*/chemistry
Viral Proteins*/genetics
Endodeoxyribonucleases*/antagonists & inhibitors
Endodeoxyribonucleases*/chemistry
Biomimetic Materials*/chemistry
Biomimetic Materials*/pharmacology
Drug Development ; Humans ; Peptides/chemistry ; Peptides/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Advanced virtual screening enables the discovery of a host-targeting and broad-spectrum antiviral agent.
Autorzy:
Chilingaryan G; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia; Biocentric.AI, 0051, Yerevan, Armenia.
Izmailyan R; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia.
Grigoryan R; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia.
Shavina A; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia; Denovo Sciences Inc., Yerevan, Armenia.
Arabyan E; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia.
Khachatryan H; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia; Denovo Sciences Inc., Yerevan, Armenia.
Abelyan N; Biocentric.AI, 0051, Yerevan, Armenia; Institute of Biomedicine and Pharmacy, Russian-Armenian University, 0051, Yerevan, Armenia.
Matevosyan M; Denovo Sciences Inc., Yerevan, Armenia.
Harutyunyan V; Denovo Sciences Inc., Yerevan, Armenia.
Manukyan G; Laboratory of Molecular and Cellular Immunology, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia.
Hietel B; Fraunhofer Institute for Cell Therapy and Immunology IZI Department of Drug Design and Target Validation MWT Biocenter, Weinbergweg 22, 06120, Halle (Saale), Germany.
Shtro A; Smorodintsev Research Institute of Influenza, 197376, St. Petersburg, Russia.
Danilenko D; Smorodintsev Research Institute of Influenza, 197376, St. Petersburg, Russia.
Zakaryan H; Laboratory of Antiviral Drug Discovery, Institute of Molecular Biology of NAS, 0014, Yerevan, Armenia; Denovo Sciences Inc., Yerevan, Armenia. Electronic address: h_.
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Źródło:
Antiviral research [Antiviral Res] 2023 Sep; Vol. 217, pp. 105681. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Oxidoreductases Acting on CH-CH Group Donors*
Humans ; Dihydroorotate Dehydrogenase ; Enzyme Inhibitors/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
New emerging SARS-CoV-2 variants and antiviral agents.
Autorzy:
Vitiello A; Ministry of Health, Directorate-General for Health Prevention, Viale Giorgio Ribotta 5, 00144, Rome, Italy. Electronic address: .
Zovi A; Ministry of Health, Viale Giorgio Ribotta 5, 00144 Rome, Italy.
Rezza G; Ministry of Health, Directorate-General for Health Prevention, Viale Giorgio Ribotta 5, 00144, Rome,Italy.
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Źródło:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2023 Sep; Vol. 70, pp. 100986. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Editorial
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19*
Humans ; SARS-CoV-2
SCR Organism:
SARS-CoV-2 variants
Opinia redakcyjna
Szczegóły
Tytuł:
Editorial: Viruses, innate immunity, and antiviral strategies: from basic research to clinical applications.
Autorzy:
Fanunza E; Department of Life and Environmental Sciences, University of Cagliari, Monserrato, Italy.
Corona A; Department of Life and Environmental Sciences, University of Cagliari, Monserrato, Italy.
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Źródło:
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Aug 08; Vol. 13, pp. 1268363. Date of Electronic Publication: 2023 Aug 08 (Print Publication: 2023).
Typ publikacji:
Editorial
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Viruses*
Immunity, Innate ; Research
Opinia redakcyjna
Szczegóły
Tytuł:
Scutellaria baicalensis: a promising natural source of antiviral compounds for the treatment of viral diseases.
Autorzy:
Huang Q; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China.
Wang M; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education & Center for Translational Medicine, Guangxi Medical University, Nanning 530021, China.
Wang M; Hainan Affiliated Hospital of Hainan Medical University, Department of Pharmacy, Haikou 570311, China.
Lu Y; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China.
Wang X; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 612505, China.
Chen X; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education & Center for Translational Medicine, Guangxi Medical University, Nanning 530021, China.
Yang X; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China.
Guo H; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China; Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education & Center for Translational Medicine, Guangxi Medical University, Nanning 530021, China. Electronic address: .
He R; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 612505, China. Electronic address: .
Luo Z; Guangxi Key Laboratory of Bioactive Molecules Research and Evaluation, College of Pharmacy, Guangxi Medical University, Nanning 530021, China. Electronic address: .
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Źródło:
Chinese journal of natural medicines [Chin J Nat Med] 2023 Aug; Vol. 21 (8), pp. 563-575.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Virus Diseases*/drug therapy
Humans ; Scutellaria baicalensis ; Medicine, Chinese Traditional
Czasopismo naukowe
Szczegóły
Tytuł:
Identification of Potential Bioactive Compounds from Aspergillus terreus against HCV NS3 Serine Protease.
Autorzy:
Lin J; School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Yang LY; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.
Pan ZD; State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, Shanghai, 201203, China.; Jecho Institute, Co., Ltd., Shanghai, 200240, China.
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Źródło:
Chemistry & biodiversity [Chem Biodivers] 2023 Aug; Vol. 20 (8), pp. e202300532. Date of Electronic Publication: 2023 Jul 17.
Typ publikacji:
Journal Article
MeSH Terms:
Serine*
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Viral Nonstructural Proteins ; Hepacivirus ; Protease Inhibitors/chemistry
SCR Organism:
Aspergillus terreus
Czasopismo naukowe
Szczegóły
Tytuł:
Antiviral activity of some benzo[g]quinazolines against coxsackievirus B4: biological screening and docking study.
Autorzy:
Abuelizz HA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Bakheit AH; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Marzouk M; Organic Chemicals Industries Division, Chemistry of Tanning Materials and Leather Technology Department, National Research Centre, Dokki, 12622, Cairo, Egypt.
El-Senousy WM; Environmental Virology Laboratory, Water Pollution Research Department, Environment and Climate Change Research Institute and Food-Borne Viruses Group, Centre of Excellence for Advanced Sciences, National Research Centre (NRC), 33 El-Buhouth Street, Dokki, 12622, Giza, Egypt.
Abdellatif MM; Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minami Osawa, Tokyo, 192-0397, Japan.
Mostafa GAE; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Saquib Q; Department of Zoology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Hassan SB; Department of Chemistry, Faculty of Science and Technology, Al-Neelain University, Khartoum, Sudan.
Al-Salahi R; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. .
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Źródło:
Pharmacological reports : PR [Pharmacol Rep] 2023 Aug; Vol. 75 (4), pp. 962-978. Date of Electronic Publication: 2023 May 21.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Quinazolines*
Child ; Humans ; Molecular Docking Simulation ; Cell Line ; RNA-Dependent RNA Polymerase
Czasopismo naukowe
Szczegóły
Tytuł:
Study of drug resistance-associated genetic mutations, and phylo-genetic analysis of HCV in the Province of Sindh, Pakistan.
Autorzy:
Faiz S; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, National Institute of Virology, University of Karachi, Karachi, 75270, Pakistan.
Irfan M; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, Jamil-ur-Rahman Center for Genome Research, University of Karachi, Karachi, 75270, Pakistan.
Farooq S; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, National Institute of Virology, University of Karachi, Karachi, 75270, Pakistan. .
Khan IA; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, Jamil-ur-Rahman Center for Genome Research, University of Karachi, Karachi, 75270, Pakistan. .
Iqbal H; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, National Institute of Virology, University of Karachi, Karachi, 75270, Pakistan.
Wahab AT; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.
Shakeel M; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, Jamil-ur-Rahman Center for Genome Research, University of Karachi, Karachi, 75270, Pakistan.
Gong P; Wuhan Institute of Virology, Chinese Academy of Sciences, No.44 Xiao Hong Shan, Wuhan, 430071, Hubei, China.
Iftner T; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, National Institute of Virology, University of Karachi, Karachi, 75270, Pakistan.; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital and Medical Faculty, Eberhard Karls University, Tuebingen, Germany.
Choudhary MI; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, National Institute of Virology, University of Karachi, Karachi, 75270, Pakistan. .; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, Jamil-ur-Rahman Center for Genome Research, University of Karachi, Karachi, 75270, Pakistan. .; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan. .; Dr. Panjwani Centre for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 27; Vol. 13 (1), pp. 12213. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Hepatitis C, Chronic*/drug therapy
Hepatitis C, Chronic*/epidemiology
Humans ; Pakistan/epidemiology ; Phylogeny ; Hepacivirus ; Genotype ; Drug Resistance, Viral/genetics ; Viral Nonstructural Proteins/genetics ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparative effectiveness of glycyrrhizic acid preparations aimed at improving liver function of patients with chronic hepatitis B: A network meta-analysis of 53 randomized controlled trials.
Autorzy:
Gao W; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China; Xiangya School of Medicine, Central South University, Changsha, Hunan 410013, China.
Zhao Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Guo L; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Wang Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Gong H; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Zhang B; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Yan M; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha 410011, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2023 Jul 25; Vol. 116, pp. 154883. Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article; Meta-Analysis
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Hepatitis B, Chronic*/drug therapy
Humans ; Glycyrrhizic Acid/pharmacology ; Glycyrrhizic Acid/therapeutic use ; Network Meta-Analysis ; Randomized Controlled Trials as Topic ; Treatment Outcome
Czasopismo naukowe
Szczegóły
Tytuł:
Mechanism of the Covalent Inhibition of Human Transmembrane Protease Serine 2 as an Original Antiviral Strategy.
Autorzy:
Spinello A; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy.
D'Anna L; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy.
Bignon E; Université de Lorraine and CNRS, UMR 7019 LPCT, F-54000 Nancy, France.
Miclot T; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy.; Université de Lorraine and CNRS, UMR 7019 LPCT, F-54000 Nancy, France.
Grandemange S; Université de Lorraine and CNRS, UMR 7039 CRAN, F-54000 Nancy, France.
Terenzi A; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy.
Barone G; Department of Biological, Chemical and Pharmaceutical Sciences, University of Palermo, 90126 Palermo, Italy.
Barbault F; Université Paris Cité and CNRS, ITODYS, F-75006 Paris, France.
Monari A; Université Paris Cité and CNRS, ITODYS, F-75006 Paris, France.
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Źródło:
The journal of physical chemistry. B [J Phys Chem B] 2023 Jul 20; Vol. 127 (28), pp. 6287-6295. Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
COVID-19*
Humans ; SARS-CoV-2 ; Cell Membrane ; Serine
Czasopismo naukowe
Szczegóły
Tytuł:
Sensing nucleotide composition in virus RNA.
Autorzy:
Lo R; Imperial College London, Department of Infectious Disease, Imperial College London, London, U.K.
Gonçalves-Carneiro D; Imperial College London, Department of Infectious Disease, Imperial College London, London, U.K.
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Źródło:
Bioscience reports [Biosci Rep] 2023 Sep 27; Vol. 43 (9).
Typ publikacji:
Review; Journal Article
MeSH Terms:
RNA, Viral*/genetics
Antiviral Agents*
Humans ; Castor Oil ; Nucleotides ; Proteome
Czasopismo naukowe
Szczegóły
Tytuł:
Antiviral Evaluation of Dispirotripiperazines against Hepatitis B Virus.
Autorzy:
Jones T; Collaborations Pharmaceuticals Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Tavis JE; Saint Louis University School of Medicine, 1100 S. Grand Blvd., St. Louis, Missouri 63104, United States.
Li Q; Saint Louis University School of Medicine, 1100 S. Grand Blvd., St. Louis, Missouri 63104, United States.
Riabova O; Research Center of Biotechnology RAS, Leninsky Prospekt 33-2, 119071 Moscow, Russia.
Monakhova N; Research Center of Biotechnology RAS, Leninsky Prospekt 33-2, 119071 Moscow, Russia.
Bradley DP; Saint Louis University School of Medicine, 1100 S. Grand Blvd., St. Louis, Missouri 63104, United States.
Lane TR; Collaborations Pharmaceuticals Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Makarov V; Research Center of Biotechnology RAS, Leninsky Prospekt 33-2, 119071 Moscow, Russia.
Ekins S; Collaborations Pharmaceuticals Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Sep 14; Vol. 66 (17), pp. 12459-12467. Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antiviral Agents*/pharmacology
Hepatitis B virus*
Humans ; Biological Assay ; Capsid ; Capsid Proteins
Czasopismo naukowe
Szczegóły
Tytuł:
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.
Autorzy:
Mihalič F; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden.
Benz C; Department of Chemistry - BMC, Uppsala University, Box 576, Husargatan 3, 751 23, Uppsala, Sweden.
Kassa E; Department of Chemistry - BMC, Uppsala University, Box 576, Husargatan 3, 751 23, Uppsala, Sweden.
Lindqvist R; Department of Clinical Microbiology, Umeå University, 90185, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 90187, Umeå, Sweden.
Simonetti L; Department of Chemistry - BMC, Uppsala University, Box 576, Husargatan 3, 751 23, Uppsala, Sweden.
Inturi R; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden.
Aronsson H; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden.
Andersson E; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden.
Chi CN; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden.
Davey NE; Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London, SW3 6JB, UK.
Överby AK; Department of Clinical Microbiology, Umeå University, 90185, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 90187, Umeå, Sweden.
Jemth P; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, Husargatan 3, 751 23, Uppsala, Sweden. .
Ivarsson Y; Department of Chemistry - BMC, Uppsala University, Box 576, Husargatan 3, 751 23, Uppsala, Sweden. .
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Źródło:
Nature communications [Nat Commun] 2023 Sep 13; Vol. 14 (1), pp. 5636. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
COVID-19*
Humans ; Protein Domains ; SARS-CoV-2 ; Ligands ; Proteomics ; Peptides/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
The virus-induced cyclic dinucleotide 2'3'-c-di-GMP mediates STING-dependent antiviral immunity in Drosophila.
Autorzy:
Cai H; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China. Electronic address: .
Li L; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Slavik KM; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Huang J; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Yin T; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Ai X; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Hédelin L; Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Haas G; Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Xiang Z; Guangdong Provincial Engineering Research Center for Ambient Mass Spectrometry, Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou, China.
Yang Y; Guangdong Provincial Engineering Research Center for Ambient Mass Spectrometry, Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology, Institute of Analysis, Guangdong Academy of Sciences (China National Analytical Center Guangzhou), Guangzhou, China.
Li X; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Chen Y; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Wei Z; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Deng H; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Chen D; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Jiao R; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China.
Martins N; Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Meignin C; Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Kranzusch PJ; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. Electronic address: philip_.
Imler JL; Sino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, China; Université de Strasbourg, CNRS UPR9022, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.
Pokaż więcej
Źródło:
Immunity [Immunity] 2023 Sep 12; Vol. 56 (9), pp. 1991-2005.e9. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Antiviral Agents*
Drosophila*
Animals ; Drosophila melanogaster ; Cyclic GMP ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
Risk Factors for the Prescription of Ineffective Antiviral Candidates for COVID-19 During the Early Pandemic Period in Korea.
Autorzy:
Lee E; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
Kim S; Transdisciplinary Department of Medicine and Advanced Technology, Seoul National University Hospital, Seoul, Korea.; College of Pharmacy, Dankook University, Cheonan, Korea.
Lee SY; Public Healthcare Center, Seoul National University Hospital, Seoul, Korea.; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jeong J; Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Korea.
Bang J; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
Oh J; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.
Shin SD; Department of Emergency Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kim NJ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Choe PG; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. .
Oh MD; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
Journal of Korean medical science [J Korean Med Sci] 2023 Sep 11; Vol. 38 (36), pp. e280. Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/therapeutic use
COVID-19*/epidemiology
Humans ; Pandemics ; COVID-19 Drug Treatment ; Retrospective Studies ; Risk Factors ; Hydroxychloroquine/therapeutic use ; Republic of Korea/epidemiology
Czasopismo naukowe
Szczegóły
Tytuł:
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation.
Autorzy:
Wu J; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Hu Y; College of Life Sciences, Nankai University, Tianjin, 300071, China.
Song J; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Xu J; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Zhang Q; National Key Laboratory of Medical Immunology, Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
Chai Y; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Wang X; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Wang B; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.
Zhao Y; Fuwai Central China Cardiovascular Hospital, Heart Center of Henan Provincial People's Hospital, Zhengzhou, 450046, China.
Cao X; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China. .
Xu X; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Sep 06; Vol. 14 (9), pp. 592. Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*
Lysine*
Animals ; Mice ; Immunity, Innate ; Interferons ; Cytokines ; Antibodies ; Methyltransferases
Czasopismo naukowe
Szczegóły
Tytuł:
PRO-2000 exhibits SARS-CoV-2 antiviral activity by interfering with spike-heparin binding.
Autorzy:
Vanderlinden E; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium. Electronic address: .
Boonen A; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Noppen S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Schoofs G; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Imbrechts M; PharmAbs, The KU Leuven Antibody Center, Herestraat 49 box 820, 3000, Leuven, Belgium.
Geukens N; PharmAbs, The KU Leuven Antibody Center, Herestraat 49 box 820, 3000, Leuven, Belgium.
Snoeck R; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Stevaert A; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Naesens L; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Andrei G; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
Schols D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, 3000, Leuven, Belgium.
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Źródło:
Antiviral research [Antiviral Res] 2023 Sep; Vol. 217, pp. 105700. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
COVID-19*
Chlorocebus aethiops ; Animals ; Humans ; Angiotensin-Converting Enzyme 2 ; Caco-2 Cells ; Vero Cells ; SARS-CoV-2 ; Protein Binding ; Spike Glycoprotein, Coronavirus
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Ubiquitination network in the type I IFN-induced antiviral signaling pathway.
Autorzy:
Zhao Q; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Zhang R; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Qiao C; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Miao Y; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Yuan Y; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Zheng H; International Institute of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, China.; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou, China.
Pokaż więcej
Źródło:
European journal of immunology [Eur J Immunol] 2023 Sep; Vol. 53 (9), pp. e2350384. Date of Electronic Publication: 2023 May 28.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antiviral Agents*
Interferon Type I*
Immunity, Innate ; Signal Transduction ; Ubiquitination
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 98376

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