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Wyszukujesz frazę ""Antiviral Agents pharmacology"" wg kryterium: Temat


Tytuł :
Search, Identification, and Design of Effective Antiviral Drugs Against Pandemic Human Coronaviruses
Autorzy :
Huang, Tianguang
Sun, Lin
Kang, Dongwei
Poongavanam, Vasanthanathan
Liu, Xinyong
Zhan, Peng
Menéndez-Arias, Luis
Pokaż więcej
Temat :
Coronavirus
MERS-CoV
Remdesivir
RNA polymerase
SARS-CoV
Viral replication
COVID-19
SARS-CoV-2
Pandemics
Humans
Antiviral Agents/pharmacology
Middle East Respiratory Syndrome Coronavirus
viruses
virus diseases
Źródło :
Huang, T, Sun, L, Kang, D, Poongavanam, V, Liu, X, Zhan, P & Menéndez-Arias, L 2021, Search, Identification, and Design of Effective Antiviral Drugs Against Pandemic Human Coronaviruses . in X Liu, P Zhan, L Menéndez-Arias & V Poongavanam (eds), Antiviral Drug Discovery and Development . Springer, Advances in Experimental Medicine and Biology, vol. 1322, pp. 219-260 . https://doi.org/10.1007/978-981-16-0267-2_9
Crossref
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2152c951589bcd9df9d04df7e6849540
https://portal.findresearcher.sdu.dk/da/publications/cef059cd-85eb-4539-b79c-7bcdda657ba7
Tytuł :
A potential robust antiviral defense state in the common vampire bat: Expression, induction and molecular characterization of the three interferon-stimulated genes -OAS1, ADAR1 and PKR
Autorzy :
Christine Neuveut
Stéphanie Dabo
Sarkis Sarkis
Marie-Claude Lise
Eliane F. Meurs
Vincent Lacoste
Anne Lavergne
Pokaż więcej
Temat :
Developmental Biology
Immunology
Interferon
medicine.drug
medicine
Biology
Homology (biology)
Transcription (biology)
Desmodus rotundus
biology.organism_classification
Virology
Gene
Vampire bat
Protein kinase R
Innate immune system
PKR
ADAR1
OAS1a
OAS1b
ISGs
Innate immunity
PKR 20
MESH: 2',5'-Oligoadenylate Synthetase/genetics
MESH: Adenosine Deaminase/genetics
MESH: Transcription, Genetic/drug effects
MESH: Transcription, Genetic/genetics
MESH: Virus Diseases/genetics
MESH: eIF-2 Kinase/genetics
MESH: Animals
MESH: Antiviral Agents/pharmacology
MESH: Cell Line
MESH: Chiroptera/genetics
MESH: Interferons/pharmacology
MESH: Poly I-C/genetics
[SDV]Life Sciences [q-bio]
[SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics
Źródło :
Crossref
Developmental and Comparative Immunology
Developmental and Comparative Immunology, Elsevier, 2018, 85, pp.95-107. ⟨10.1016/J.DCI.2018.04.006⟩
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e58b3847c55cac981f1ea20ac5c8f2
https://api.elsevier.com/content/article/PII:S0145305X18300995?httpAccept=text/xml
Tytuł :
Type I interferon-mediated autoinflammation due to DNase II deficiency
Autorzy :
Rodero, Mathieu P.
Tesser, Alessandra
Bartok, Eva
Rice, Gillian I.
Della Mina, Erika
Depp, Marine
Beitz, Benoit
Bondet, Vincent
Cagnard, Nicolas
Duffy, Darragh
Dussiot, Michael
Frémond, Marie-Louise
Gattorno, Marco
Guillem, Flavia
Kitabayashi, Naoki
Porcheray, Fabrice
Rieux-Laucat, Frederic
Seabra, Luis
Uggenti, Carolina
Volpi, Stefano
Zeef, Leo A H.
Alyanakian, Marie-Alexandra
Beltrand, Jacques
Bianco, Anna Monica
Boddaert, Nathalie
Brouzes, Chantal
Candon, Sophie
Caorsi, Roberta
Charbit, Marina
Fabre, Monique
Faletra, Flavio
Girard, Muriel
Harroche, Annie
Hartmann, Evelyn
Lasne, Dominique
Marcuzzi, Annalisa
Neven, Bénédicte
Nitschke, Patrick
Pascreau, Tiffany
Pastore, Serena
Picard, Capucine
Picco, Paolo
Piscianz, Elisa
Polak, Michel
Quartier, Pierre
Rabant, Marion
Stocco, Gabriele
Taddio, Andrea
Uettwiller, Florence
Valencic, Erica
Vozzi, Diego
Hartmann, Gunther
Barchet, Winfried
Hermine, Olivier
Bader-Meunier, Brigitte
Tommasini, Alberto
Crow, Yanick J.
Pokaż więcej
Temat :
lcsh:Science
lcsh:Q
[SDV.IMM]Life Sciences [q-bio]/Immunology
Science
General Physics and Astronomy
General Biochemistry, Genetics and Molecular Biology
General Chemistry
Downregulation and upregulation
Antibody
biology.protein
biology
STAT1
Haematopoiesis
Alpha interferon
Interferon
medicine.drug
medicine
Membranoproliferative glomerulonephritis
medicine.disease
Immunology
Nucleic acid
[SDV]Life Sciences [q-bio]
Article
Chemistry (all)
Biochemistry, Genetics and Molecular Biology (all)
Physics and Astronomy (all)
DNASE2
type I interferon
autoinflammation
exome sequencing
Adolescent
Antiviral Agents/pharmacology
Child
Deoxyribonucleases/deficiency
Endodeoxyribonucleases/deficiency
Erythroblasts/immunology
Female
Gene Expression Profiling
Hematopoiesis/immunology
Hereditary Autoinflammatory Diseases/blood
Humans
Interferon-alpha/blood
Male
Mutation
Phosphorylation
RNA, Messenger/analysis
STAT1 Transcription Factor/metabolism
STAT3 Transcription Factor/metabolism
Sequence Analysis, RNA
Signal Transduction/immunology
Up-Regulation/drug effects
NO
DNASE2, type I interferon, autoinflammation, exome sequencing
LS3_11
Źródło :
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.2176. ⟨10.1038/s41467-017-01932-3⟩
Crossref
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/S41467-017-01932-3⟩
Rodero, M P, Tesser, A, Bartok, E, Rice, G, Della Mina, E, Depp, M, Beitz, B, Bondet, V, Cagnard, N, Duffy, D, Dussiot, M, Fremond, M-L, Gattorno, M, Guillem, F, Kitabayashi, N, Porcheray, F, Rieux-Laucat, F, Seabra, L, Uggenti, C, Volpi, S, Zeef, L, Alyanakian, M-A, Beltrand, J, Bianco, A M, Boddaert, N, Brouzes, C, Candon, S, Caorsi, R, Charbit, M, Fabre, M, Faletra, F, Girard, M, Harroche, A, Hartmann, E, Lasne, D, Marcuzzi, A, Neven, B, Nitschke, P, Pascreau, T, Pastore, S, Picard, C, Picco, P P, Piscianz, E, Polak, M, Quartier, P, Rabant, M, Stocco, G, Taddio, A, Uettwiller, F, Valencic, E, Vozzi, D, Hartmann, G, Barchet, W, Hermine, O, Bader-Meunier, B, Tommasini, A & Crow, Y 2017, ' Type I interferon mediated autoinflammation due to DNase II deficiency ', Nature Communications, vol. 8, 2176 . https://doi.org/10.1038/s41467-017-01932-3
Rodero, M P, Tesser, A, Bartok, E, Rice, G I, Della Mina, E, Depp, M, Beitz, B, Bondet, V, Cagnard, N, Duffy, D, Dussiot, M, Frémond, M, Gattorno, M, Guillem, F, Kitabayashi, N, Porcheray, F, Rieux-laucat, F, Seabra, L, Uggenti, C, Volpi, S, Zeef, L A H, Alyanakian, M, Beltrand, J, Bianco, A M, Boddaert, N, Brouzes, C, Candon, S, Caorsi, R, Charbit, M, Fabre, M, Faletra, F, Girard, M, Harroche, A, Hartmann, E, Lasne, D, Marcuzzi, A, Neven, B, Nitschke, P, Pascreau, T, Pastore, S, Picard, C, Picco, P, Piscianz, E, Polak, M, Quartier, P, Rabant, M, Stocco, G, Taddio, A, Uettwiller, F, Valencic, E, Vozzi, D, Hartmann, G, Barchet, W, Hermine, O, Bader-meunier, B, Tommasini, A & Crow, Y J 2017, ' Type I interferon-mediated autoinflammation due to DNase II deficiency ', Nature Communications, vol. 8, no. 1, 2176 . https://doi.org/10.1038/s41467-017-01932-3
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7996f15867050dcd49eb11d20f8f073
http://link.springer.com/article/10.1038/s41467-017-01932-3
Tytuł :
The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K Is Species Specific
Autorzy :
Christine Goffinet
Passos
Christina M. Stürzel
M Rotger
Aparna Ponnurangam
Ellen Ewald
Angelina Malassa
G Ssebyatika
Frank Kirchhoff
Lodermeyer
Christine S. Falk
Amalio Telenti
Thomas Krey
Pokaż więcej
Temat :
Amino Acid Sequence
Animals
Antigens, Neoplasm/chemistry
Antigens, Neoplasm/pharmacology
Antiviral Agents/pharmacology
Biomarkers, Tumor/chemistry
Biomarkers, Tumor/pharmacology
Carrier Proteins/chemistry
Carrier Proteins/pharmacology
Gene Products, env/metabolism
Glycoproteins/chemistry
Glycoproteins/pharmacology
HIV Infections/drug therapy
HIV Infections/virology
HIV-1/drug effects
Humans
Macaca mulatta
Protein Conformation
Sequence Homology
Simian Acquired Immunodeficiency Syndrome/drug therapy
Simian Acquired Immunodeficiency Syndrome/virology
Simian Immunodeficiency Virus/drug effects
Species Specificity
Virus Assembly/drug effects
Virus Replication/drug effects
antiviral
human immunodeficiency virus
interferons
restriction factor
virus infectivity
Virus-Cell Interactions
Virology
Insect Science
Immunology
Microbiology
Infectivity
Glycoprotein
chemistry.chemical_classification
chemistry
Homology (biology)
Cell
medicine.anatomical_structure
medicine
Antiviral protein
Amino acid
Biology
Cell biology
Rhesus macaque
biology.organism_classification
Zinc finger
Źródło :
Journal of virology, vol. 92, no. 14, pp. 1
Journal of virology
Journal of Virology
Crossref
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eead4ffd8307f20fbf21abaf24c5bbb
https://serval.unil.ch/resource/serval:BIB_46A7AAA28FE7.P001/REF.pdf
Tytuł :
Baseline and post-treatment hepatitis C NS5A resistance in relapsed patients from a multicentric real-life cohort
Autorzy :
Laurent Chiche
Jacques Izopet
Victor de Ledinghen
Sofiane Mohamed
Hacène Khiri
Sylvie Larrat
Fabien Zoulim
Philippe Halfon
Vincent Leroy
Laurent Alric
Caroline Scholtes
Anne Plauzolles
Guillaume Penaranda
Sophie Metivier
Denis Ouzan
Marc Bourlière
M.A. Thelu
Florence Abravanel
Pascale Trimoulet
Pokaż więcej
Temat :
[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Antiviral Agents / pharmacology
Antiviral Agents / therapeutic use
DNA Mutational Analysis
Drug Resistance
Viral
Drug Therapy
Female
Genotype
Hepacivirus / drug effects
Hepacivirus / genetics
Hepatitis C / drug therapy
Hepatitis C / virology
Humans
Male
Treatment Failure
Treatment Outcome
Viral Load
Viral Nonstructural Proteins / antagonists & inhibitors
Viral Nonstructural Proteins / genetics
[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences
Infectious Diseases
Pharmacology (medical)
Pharmacology
Regimen
Cohort
NS5A
Internal medicine
medicine.medical_specialty
medicine
Hepatitis C
medicine.disease
Drug resistance
Viral load
business.industry
business
Pharmacotherapy
Źródło :
Antiviral Therapy
Antiviral Therapy, International Medical Press, 2018, 23 (4), pp.307-314. ⟨10.3851/IMP3184⟩
Antiviral Therapy, International Medical Press, 2018, 23 (4), pp.307-314
Crossref
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::651d92d564ba9cda0bb0d52eb54f93d2
https://hal.archives-ouvertes.fr/hal-02059894
Tytuł :
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
Autorzy :
Bartenschlager, Ralf
Baumert, Thomas F.
Bukh, Jens
Houghton, Michael
Lemon, Stanley M.
Lindenbach, Brett D.
Lohmann, Volker
Moradpour, Darius
Pietschmann, Thomas
Rice, Charles M.
Thimme, Robert
Wakita, Takaji
Pokaż więcej
Temat :
Antiviral Agents/pharmacology/therapeutic use
Capital Financing
Drug Resistance
Viral
Hepacivirus/drug effects/physiology
Hepatitis C
Chronic/drug therapy/prevention and control/*virology
Humans
Public Health
Research/economics
Research Personnel
Translational Medical Research
Viral Vaccines/immunology
Workforce
Direct acting antiviral therapy
HCV research funding
HCV vaccine
Immune reconstitution
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Cancer Research
Infectious Diseases
Virology
Cancer risk
Hepatitis C virus
medicine.disease_cause
medicine
Hcv vaccine
Liver disease
medicine.disease
Biology
Intensive care medicine
medicine.medical_specialty
Chronic hepatitis
Antiviral therapy
Virus
Antiviral Agents/pharmacology
Antiviral Agents/therapeutic use
Drug Resistance, Viral
Hepacivirus/drug effects
Hepacivirus/physiology
Hepatitis C, Chronic/drug therapy
Hepatitis C, Chronic/prevention & control
Hepatitis C, Chronic/virology
Research/manpower
Journal Article
Review
Źródło :
Virus Research
Virus Research, 2018, 248, pp.53-62. ⟨10.1016/j.virusres.2018.02.016⟩
Crossref
Virus research
Netherlands
Virus research, vol. 248, pp. 53-62
Bartenschlager, R, Baumert, T F, Bukh, J, Houghton, M, Lemon, S M, Lindenbach, B D, Lohmann, V, Moradpour, D, Pietschmann, T, Rice, C M, Thimme, R & Wakita, T 2018, ' Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy : Considerations for scientists and funding agencies ', Virus Research, vol. 248, pp. 53-62 . https://doi.org/10.1016/j.virusres.2018.02.016
Opis pliku :
application/pdf
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6b05d87c7c36098f27aba8721d231f
https://hal.archives-ouvertes.fr/hal-02460239
Tytuł :
Virtual Screening in Hepatitis B Virus Drug Discovery: Current State- of-the-Art and Future Perspectives
Autorzy :
Arnaud Blondel
Mohcine Elmessaoudi-Idrissi
Anass Kettani
Marc P. Windisch
Sayeh Ezzikouri
Soumaya Benjelloun
Pokaż więcej
Temat :
workflow
inhibitors
structure-based virtual screening
docking
quantitative structure-activity rela- tionships
Hepatitis B Virus
Ligand-based virtual screening
MESH: Antiviral Agents/chemistry
MESH: Antiviral Agents/pharmacology
MESH: Hepatitis B/virology
MESH: Hepatitis B virus/drug effects
MESH: Humans
MESH: Hepatitis B virus/metabolism
MESH: Molecular Docking Simulation
MESH: Organic Anion Transporters, Sodium-Dependent/antagonists & inhibitors
MESH: Organic Anion Transporters, Sodium-Dependent/metabolism
MESH: Quantitative Structure-Activity Relationship
MESH: RNA-Directed DNA Polymerase/chemistry
MESH: RNA-Directed DNA Polymerase/metabolism
MESH: Symporters/metabolism
MESH: Symporters/antagonists & inhibitors
MESH: Trans-Activators/antagonists & inhibitors
MESH: Antiviral Agents/therapeutic use
MESH: Trans-Activators/metabolism
MESH: Capsid Proteins/antagonists & inhibitors
MESH: Capsid Proteins/metabolism
MESH: Hepatitis B/drug therapy
MESH: Hepatitis B/pathology
[CHIM.CHEM]Chemical Sciences/Cheminformatics
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]
[SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
Pharmacology
Molecular Medicine
Drug Discovery
Biochemistry
Organic Chemistry
Drug
media_common.quotation_subject
media_common
Drug discovery
Global health
Medicine
business.industry
business
Virtual screening
In silico
Clinical trial
Hepatitis B virus
medicine.disease_cause
Alpha interferon
Bioinformatics
Źródło :
Current Medicinal Chemistry
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Crossref
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5619f110d1c8caa76ef3dfca0e7a17e0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02503267
Tytuł :
Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes
Autorzy :
Massimo Levrero
Fanny Lebossé
Barbara Testoni
Maria Francesca Donato
Judith Fresquet
David Durantel
Fabien Zoulim
Francesco Negro
François Helle
Pokaż więcej
Temat :
Gastroenterology
Epigenetics
Immunology
Histone methyltransferase
Interferon
medicine.drug
medicine
Cancer research
In vivo
Ribavirin
chemistry.chemical_compound
chemistry
Regulation of gene expression
Downregulation and upregulation
Chromatin immunoprecipitation
Biology
ddc:616
ddc:616.07
Antiviral Agents/pharmacology
Blotting
Western
Cells
Cultured
Enzyme-Linked Immunosorbent Assay
Epigenomics
Gene Expression/drug effects
Hepacivirus/drug effects
Hepatitis C
Chronic
Hepatocytes/drug effects/metabolism
Histone-Lysine N-Methyltransferase/metabolism
Humans
Immunoprecipitation
Interferon-alpha/genetics/pharmacology
RNA
Messenger/drug effects
Real-Time Polymerase Chain Reaction
Ribavirin/pharmacology
Transfection
Viral Load
Virus Replication/drug effects
pathology
Infection
Hepatocytes
France
Environment
Chromatin Immunoprecipitation
Chromatin
Biopsy
Patients
Italy
therapy
Switzerland
Medicine
Liver
[SDV.CAN]Life Sciences [q-bio]/Cancer
virus diseases
Źródło :
Crossref
Gut, Vol. 65, No 4 (2016) pp. 672-682
Gut
Gut, BMJ Publishing Group, 2016, 65 (4), pp.672-682. ⟨10.1136/gutjnl-2014-309011⟩
Dostępność :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587b3ca40bccc062c997fb8fe9f62898
https://syndication.highwire.org/content/doi/10.1136/gutjnl-2014-309011

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