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Wyszukujesz frazę ""Apoptosis"" wg kryterium: Temat


Starter badań:

Tytuł:
Escaping cell death via TRAIL decoy receptors: a systematic review of their roles and expressions in colorectal cancer.
Autorzy:
Jong KXJ; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Mohamed EHM; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Ibrahim ZA; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. .
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Źródło:
Apoptosis : an international journal on programmed cell death [Apoptosis] 2022 Dec; Vol. 27 (11-12), pp. 787-799. Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Systematic Review; Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Humans ; Apoptosis ; TNF-Related Apoptosis-Inducing Ligand/genetics ; TNF-Related Apoptosis-Inducing Ligand/therapeutic use ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; Cell Death ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells.
Autorzy:
Yerbes R; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain.; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Carlos III Health Institute, Madrid, Spain.
Mora-Molina R; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain.
Fernández-Farrán FJ; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain.
Hiraldo L; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain.
López-Rivas A; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain. .; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Carlos III Health Institute, Madrid, Spain. .
Palacios C; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, CSIC-Universidad de Sevilla-Universidad Pablo de Olavide, Avda Américo Vespucio 24, 41092, Sevilla, Spain. .; Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Carlos III Health Institute, Madrid, Spain. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Oct 27; Vol. 13 (10), pp. 906. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
Glutamine*/metabolism
Receptors, TNF-Related Apoptosis-Inducing Ligand*/genetics
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
Apoptosis ; CASP8 and FADD-Like Apoptosis Regulating Protein/metabolism ; Caspase 8/metabolism ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; Tumor Necrosis Factor-alpha/metabolism ; Protein Kinases/metabolism
Czasopismo naukowe
Tytuł:
DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma.
Autorzy:
Yagolovich AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia.; Manebio LLC, 115280 Moscow, Russia.
Isakova AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia.
Artykov AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.; Manebio LLC, 115280 Moscow, Russia.
Vorontsova YV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Mazur DV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Antipova NV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Pavlyukov MS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Shakhparonov MI; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Gileva AM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Markvicheva EA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Plotnikova EA; National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, P.A. Hertsen Moscow Oncology Research Institute, 125284 Moscow, Russia.
Pankratov AA; National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, P.A. Hertsen Moscow Oncology Research Institute, 125284 Moscow, Russia.
Kirpichnikov MP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia.
Gasparian ME; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.
Dolgikh DA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 117997 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119192 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 21; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
TNF-Related Apoptosis-Inducing Ligand*/genetics
TNF-Related Apoptosis-Inducing Ligand*/pharmacology
TNF-Related Apoptosis-Inducing Ligand*/metabolism
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Humans ; Mice ; Animals ; Integrin alphaVbeta3/genetics ; Cell Line, Tumor ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Apoptosis
Czasopismo naukowe
Tytuł:
AI-Based Protein Interaction Screening and Identification (AISID).
Autorzy:
Fu ZQ; SER-CAT, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.; Department of Biochemistry & Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Sha HL; Department of Cell, Developmental and Integrative Biology (CDIB), University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Sha B; Department of Cell, Developmental and Integrative Biology (CDIB), University of Alabama at Birmingham, Birmingham, AL 35294, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 02; Vol. 23 (19). Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Tumor Necrosis Factor*/genetics
Receptors, Tumor Necrosis Factor*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/genetics
TNF-Related Apoptosis-Inducing Ligand*/metabolism
Apoptosis ; Artificial Intelligence ; Humans ; Protein Binding ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Involvement of Bid in the crosstalk between ferroptotic agent-induced ER stress and TRAIL-induced apoptosis.
Autorzy:
Kim JH; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Najy AJ; Department of Pathology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Oncology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.
Li J; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Luo X; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Kim HC; Department of Pathology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Oncology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.
Choudry MHA; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lee YJ; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2022 Nov; Vol. 237 (11), pp. 4180-4196. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis*
Ovarian Neoplasms*/pathology
Humans ; Female ; Cell Line, Tumor ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; BH3 Interacting Domain Death Agonist Protein/genetics ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Caspase 8/metabolism ; Endoplasmic Reticulum Stress ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Covalent conjugation of ubiquitin-like ISG15 to apoptosis-inducing factor exacerbates toxic stimuli-induced apoptotic cell death.
Autorzy:
Jeon SJ; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
Chung KC; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Oct; Vol. 298 (10), pp. 102464. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Inducing Factor*/genetics
Apoptosis Inducing Factor*/metabolism
Ubiquitins*/genetics
Ubiquitins*/metabolism
Humans ; Apoptosis ; Etoposide/pharmacology ; A549 Cells
Czasopismo naukowe
Tytuł:
XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.
Autorzy:
Nishimura Y; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Iwashita M; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. .
Hayashi M; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Shinjo T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Watanabe Y; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Zeze T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yamashita A; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Fukuda T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Sanui T; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Sano T; Department of Cell Biology and Pharmacology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Asano T; Department of Medical Chemistry, Division of Molecular Medical Science, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Nishimura F; Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
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Źródło:
Acta diabetologica [Acta Diabetol] 2022 Oct; Vol. 59 (10), pp. 1275-1286. Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Apoptosis Regulatory Proteins*/genetics
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Insulin-Secreting Cells*/metabolism
Islets of Langerhans*/metabolism
Animals ; Apoptosis/genetics ; Diet, High-Fat/adverse effects ; Insulin/metabolism ; Insulin Secretion ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
BCL-2-family protein tBID can act as a BAX-like effector of apoptosis.
Autorzy:
Flores-Romero H; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Hohorst L; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
John M; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Albert MC; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
King LE; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Beckmann L; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Szabo T; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Hertlein V; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Luo X; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, ME, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Villunger A; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Frenzel LP; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Kashkar H; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
Garcia-Saez AJ; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
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Źródło:
The EMBO journal [EMBO J] 2022 Dec 17; Vol. 41 (2), pp. e108690. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
BH3 Interacting Domain Death Agonist Protein/*metabolism
Apoptosis Regulatory Proteins/metabolism ; BH3 Interacting Domain Death Agonist Protein/chemistry ; BH3 Interacting Domain Death Agonist Protein/genetics ; HCT116 Cells ; HeLa Cells ; Humans ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Protein Domains ; Proteolysis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro .
Autorzy:
Yang Y; School of Pharmacy, Guilin Medical University, Guilin, PR China.; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Ren ZZ; School of Pharmacy, Guilin Medical University, Guilin, PR China.; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Wei WJ; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; Department of Laboratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, PR China.
He ZL; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.
Deng YL; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.
Wang Z; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.
Fan YC; Medical College, Guangxi University, Nanning, PR China.
Zhou J; Medical College, Guangxi University, Nanning, PR China.
Jiang LH; School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, PR China.; College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China.; Medical College, Guangxi University, Nanning, PR China.; Key Laboratory of Tumor Immunology and Pathology (Army Medical University), Ministry of Education, Chongqing, PR China.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 1566-1577.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Nasopharyngeal Neoplasms*/drug therapy
Nasopharyngeal Neoplasms*/metabolism
Nasopharyngeal Neoplasms*/pathology
Apoptosis Regulatory Proteins ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Coumarins ; Humans ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Carcinoma/pathology ; RNA/pharmacology ; RNA/therapeutic use ; Reactive Oxygen Species
Czasopismo naukowe
Tytuł:
Expression, purification, and characterization of c-FLIP tandem death effector domains from Escherichia coli.
Autorzy:
Bai ZQ; Innovative Institute of Chinese Medicine and Pharmacy, University of Traditional Chinese Medicine, Chengdu, 611137, China; College of Science, Yunnan Agricultural University, Kunming, 650201, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Hu K; Innovative Institute of Chinese Medicine and Pharmacy, University of Traditional Chinese Medicine, Chengdu, 611137, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. Electronic address: .
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Źródło:
Protein expression and purification [Protein Expr Purif] 2022 Dec; Vol. 200, pp. 106168. Date of Electronic Publication: 2022 Sep 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CASP8 and FADD-Like Apoptosis Regulating Protein*/genetics
CASP8 and FADD-Like Apoptosis Regulating Protein*/metabolism
Death Effector Domain*
Apoptosis ; Caspase 8/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Follow-Up Studies
Czasopismo naukowe
Tytuł:
Decoding the concealed transcriptional signature of the apoptosis-related BCL2 antagonist/killer 1 (BAK1) gene in human malignancies.
Autorzy:
Athanasopoulou K; Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, 15701, Athens, Greece.
Adamopoulos PG; Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, 15701, Athens, Greece.
Daneva GN; Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, 15701, Athens, Greece.
Scorilas A; Department of Biochemistry and Molecular Biology, National and Kapodistrian University of Athens, 15701, Athens, Greece. .
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Źródło:
Apoptosis : an international journal on programmed cell death [Apoptosis] 2022 Dec; Vol. 27 (11-12), pp. 869-882. Date of Electronic Publication: 2022 Jul 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/genetics
bcl-2 Homologous Antagonist-Killer Protein*/genetics
bcl-2 Homologous Antagonist-Killer Protein*/metabolism
Neoplasms*/genetics
Humans ; Alternative Splicing/genetics ; Apoptosis Regulatory Proteins/metabolism ; Protein Isoforms/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL-2/BCL-XL pathway augmenting apoptosis in ovarian cancer.
Autorzy:
Chen Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Li N; Department of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Li K; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Tang M; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Zhao X; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Guo W; Department of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, Sichuan Province, China.
Tong A; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Nie C; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Peng Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China.
Yuan Z; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Sichuan University, 17 People's South Road, Chengdu 610041, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2022 Dec 01; Vol. 1868 (12), pp. 166553. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Cisplatin*/pharmacology
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/metabolism
Proto-Oncogene Proteins*/genetics
Proto-Oncogene Proteins*/metabolism
Apoptosis ; Female ; Humans ; Hydrogen Peroxide/pharmacology ; Paclitaxel/pharmacology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism ; Thioredoxins/genetics ; Thioredoxins/metabolism ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł:
Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1.
Autorzy:
Lim D; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Jin S; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea.
Shin HC; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea.
Kim W; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Choi JS; Department of Biochemistry, Chungnam National University, Daejeon, 34134, South Korea.
Oh DB; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, 34113, South Korea.
Kim SJ; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, 34113, South Korea. Electronic address: .
Seo J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea. Electronic address: .
Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 34141, South Korea. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 15; Vol. 625, pp. 174-180. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Testis*/metabolism
Amino Acid Sequence ; Amino Acids/metabolism ; Animals ; Apoptosis ; HeLa Cells ; Humans ; Male ; Mice ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł:
BID- and BAX-mediated mitochondrial pathway dominates A-1331852-induced apoptosis in senescent A549 cells.
Autorzy:
Wu G; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Li X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Zhan Y; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Fan X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Xu L; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Chen T; MOE Key Laboratory of Laser Life Science & Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, 510631, China.
Wang X; Department of Pain Management, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 30; Vol. 627, pp. 160-167. Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Mitochondria*/metabolism
BH3 Interacting Domain Death Agonist Protein/*metabolism
A549 Cells ; Apoptosis Regulatory Proteins/metabolism ; Benzothiazoles ; Humans ; Isoquinolines ; Poly(ADP-ribose) Polymerases/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł:
Deubiquitinating Enzyme USP12 Regulates the Pro-Apoptosis Protein Bax.
Autorzy:
Choi HS; Department of Biomedical Science, CHA University, Seongnam 13488, Gyeonggi-do, Korea.
Lim ES; Department of Biomedical Science, CHA University, Seongnam 13488, Gyeonggi-do, Korea.
Baek KH; Department of Biomedical Science, CHA University, Seongnam 13488, Gyeonggi-do, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 28; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Ubiquitin Thiolesterase*/genetics
Ubiquitin Thiolesterase*/metabolism
bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Ubiquitination ; Apoptosis
Czasopismo naukowe
Tytuł:
Ras suppressor 1 long form (RSU1L) silencing promotes apoptosis in invasive breast cancer cells.
Autorzy:
Christou C; Cancer Metastasis and Adhesion Laboratory, Basic and Translational Cancer Research Center (BTCRC), Nicosia, Cyprus. Electronic address: .
Christodoulou MI; Biomedical Sciences Program, Department of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus; Tumor Immunology and Biomarkers Laboratory, Basic and Translational Cancer Research Center (BTCRC), Nicosia, Cyprus. Electronic address: .
Zaravinos A; Biological Sciences Program, Department of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus; Cancer Genetics, Genomics and Systems Biology Laboratory, Basic and Translational Cancer Research Center (BTCRC), Nicosia, Cyprus. Electronic address: .
Gkretsi V; Cancer Metastasis and Adhesion Laboratory, Basic and Translational Cancer Research Center (BTCRC), Nicosia, Cyprus; Biomedical Sciences Program, Department of Life Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus. Electronic address: .
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Źródło:
Cellular signalling [Cell Signal] 2023 Jan; Vol. 101, pp. 110522. Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Breast Neoplasms*/pathology
Transcription Factors*/genetics
Transcription Factors*/metabolism
Female ; Humans ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Cell Line, Tumor ; MCF-7 Cells ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA, Small Interfering/genetics ; Gene Silencing ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism
Czasopismo naukowe
Tytuł:
Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis.
Autorzy:
Suksri K; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Semprasert N; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Limjindaporn T; Department of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Yenchitsomanus PT; Division of Molecular Medicine, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kooptiwoot S; Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kooptiwut S; Division of Endocrinology, Department of Physiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand. S_.
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 28; Vol. 12 (1), pp. 12950. Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/pharmacology
Animals ; Apoptosis ; Apoptosis Regulatory Proteins/metabolism ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Line, Tumor ; Dexamethasone/adverse effects ; Genistein/pharmacology ; Mice ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Superoxides/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
CRISPRi screening identifies CASP8AP2 as an essential viability factor in lung cancer controlling tumor cell death via the AP-1 pathway.
Autorzy:
Myacheva K; Division of Cancer Research, Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK) - Partner Site Freiburg, Germany; Division of RNA Biology & Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Walsh A; siTOOLs Biotech GmbH, Lochhamerstr. 29A, Planegg, Martinsried, Germany.
Riester M; Division of Cancer Research, Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK) - Partner Site Freiburg, Germany.
Pelos G; Division of Cancer Research, Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK) - Partner Site Freiburg, Germany.
Carl J; Division of Cancer Research, Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK) - Partner Site Freiburg, Germany.
Diederichs S; Division of Cancer Research, Department of Thoracic Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK) - Partner Site Freiburg, Germany; Division of RNA Biology & Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2023 Jan 01; Vol. 552, pp. 215958. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/metabolism
Lung Neoplasms*/metabolism
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Calcium-Binding Proteins*/genetics
Calcium-Binding Proteins*/metabolism
Humans ; Apoptosis/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats ; Early Detection of Cancer ; Lung/pathology ; Transcription Factor AP-1/genetics ; Transcription Factor AP-1/metabolism
Czasopismo naukowe
Tytuł:
XIAP as a multifaceted molecule in Cellular Signaling.
Autorzy:
Hanifeh M; Department of Biochemistry, Faculty of Biological Sciences, Trabiat Modares University, Tehran, Iran.
Ataei F; Department of Biochemistry, Faculty of Biological Sciences, Trabiat Modares University, Tehran, Iran. ataei_.
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Źródło:
Apoptosis : an international journal on programmed cell death [Apoptosis] 2022 Aug; Vol. 27 (7-8), pp. 441-453. Date of Electronic Publication: 2022 Jun 04.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
X-Linked Inhibitor of Apoptosis Protein*/genetics
Caspases/metabolism ; Cell Death ; Inhibitor of Apoptosis Proteins
Czasopismo naukowe
Tytuł:
Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS).
Autorzy:
Tsintari V; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany.
Walter B; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany.
Fend F; Institute of Pathology, University Hospital Tübingen, Tübingen, Germany.
Overkamp M; Institute of Pathology, University Hospital Tübingen, Tübingen, Germany.
Rothermundt C; Department of Medical Oncology and Hematology, Cantonal Hospital St. Gallen (KSSG), St. Gallen, Switzerland.
Lopez CD; Department of Hematology and Medical Oncology, Oregon Health and Science University (OHSU), Portland, OR, USA.
Schittenhelm MM; Department of Medical Oncology and Hematology, Cantonal Hospital St. Gallen (KSSG), St. Gallen, Switzerland.
Kampa-Schittenhelm KM; Department of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen (UKT), Tübingen, Germany. .; Laboratory of Translational Experimental Hematology and Oncology, Medical Research Center and Department of Medical Oncology and Hematology, Cantonal Hospital, Rorschacherstr. 95, St. Gallen, 9007, Switzerland, St.Gallen. .; St. Gallen, Switzerland. .
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Źródło:
BMC cancer [BMC Cancer] 2022 Jul 02; Vol. 22 (1), pp. 725. Date of Electronic Publication: 2022 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Carcinogenesis*/genetics
Carcinogenesis*/metabolism
Rhabdomyosarcoma*/genetics
Rhabdomyosarcoma*/metabolism
Sarcoma*/genetics
Sarcoma*/metabolism
Soft Tissue Neoplasms*/genetics
Soft Tissue Neoplasms*/metabolism
Alternative Splicing ; Apoptosis/genetics ; Drug Resistance, Neoplasm/genetics ; Drug Resistance, Neoplasm/physiology ; Humans ; Protein Isoforms/metabolism ; RNA, Messenger/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe

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