Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Apoptosis"" wg kryterium: Temat


Starter badań:

Tytuł:
Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate.
Autorzy:
Abbas H; Université Oran 1, Ahmed Ben Bella, Oran 31000, Algeria.
Derkaoui DK; Université Oran 1, Ahmed Ben Bella, Oran 31000, Algeria.
Jeammet L; Jalon Therapeutics, 75010 Paris, France.
Adicéam E; Jalon Therapeutics, 75010 Paris, France.
Tiollier J; Jalon Therapeutics, 75010 Paris, France.
Sicard H; Jalon Therapeutics, 75010 Paris, France.
Braun T; Laboratoire de Transfert des Leucémies, EA3518, Institut de Recherche Saint Louis, Hôpital Saint Louis, Université de Paris, 75010 Paris, France.; AP-HP, Service d'Hématologie Clinique, Hôpital Avicenne, Université Paris XIII, 93000 Bobigny, France.; OPALE Carnot Institute, The Organization for Partnerships in Leukemia, Hôpital Saint-Louis, 75010 Paris, France.
Poyet JL; INSERM UMRS976, Institut de Recherche Saint Louis, Hôpital Saint Louis, 75010 Paris, France.; Université Paris Cité, 75015 Paris, France.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2024 Jan 22; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Neoplasms*/genetics
Humans ; Nuclear Proteins/metabolism ; Apoptosis ; Cell Differentiation
Czasopismo naukowe
Tytuł:
cFLIP L acts as a suppressor of TRAIL- and Fas-initiated inflammation by inhibiting assembly of caspase-8/FADD/RIPK1 NF-κB-activating complexes.
Autorzy:
Davidovich P; Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland.
Higgins CA; Centre for Cancer Research and Cell Biology, Queen's University, Belfast, UK.
Najda Z; Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland.
Longley DB; Centre for Cancer Research and Cell Biology, Queen's University, Belfast, UK.
Martin SJ; Molecular Cell Biology Laboratory, Department of Genetics, The Smurfit Institute, Trinity College, Dublin 2, Ireland. Electronic address: .
Pokaż więcej
Źródło:
Cell reports [Cell Rep] 2023 Dec 26; Vol. 42 (12), pp. 113476. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NF-kappa B*/metabolism
Apoptosis Regulatory Proteins*/pharmacology
Humans ; Caspase 8/metabolism ; Apoptosis ; Inflammation ; Cytokines/pharmacology ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases ; Fas-Associated Death Domain Protein/metabolism
Czasopismo naukowe
Tytuł:
Apoptosis is mediated by FeHV-1 through the intrinsic pathway and interacts with the autophagic process.
Autorzy:
Ferrara G; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy. .
Longobardi C; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Sgadari MF; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Restucci B; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Iovane G; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Ciarcia R; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Pagnini U; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Montagnaro S; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino n.1, Naples, 80137, Italy.
Pokaż więcej
Źródło:
Virology journal [Virol J] 2023 Dec 12; Vol. 20 (1), pp. 295. Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Caspases*/metabolism
Cats ; Animals ; Caspase 3 ; Apoptosis Regulatory Proteins ; NF-kappa B/metabolism ; Autophagy
Czasopismo naukowe
Tytuł:
Role of APR3 in cancer: apoptosis, autophagy, oxidative stress, and cancer therapy.
Autorzy:
Zhang P; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China.; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, Zhejiang, China.; School of Pharmacy, Hangzhou Medical College, 310000, Hangzhou, Zhejiang, China.
Zhou C; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China.
Jing Q; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China.
Gao Y; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China.; School of Pharmacy, Hangzhou Medical College, 310000, Hangzhou, Zhejiang, China.
Yang L; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China.
Li Y; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, Zhejiang, China.
Du J; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China. .
Tong X; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China. .; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, Zhejiang, China. .
Wang Y; Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 310014, Hangzhou, Zhejiang, China. .; Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Clinical Research Center, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, 310006, Hangzhou, Zhejiang, China. .; Department of Clinical Research Center, Luqiao Second People's Hospital, 317200, Taizhou, Zhejiang, China. .
Pokaż więcej
Źródło:
Apoptosis : an international journal on programmed cell death [Apoptosis] 2023 Dec; Vol. 28 (11-12), pp. 1520-1533. Date of Electronic Publication: 2023 Aug 27.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/genetics
Neoplasms*/genetics
Neoplasms*/therapy
Humans ; Apoptosis Regulatory Proteins/metabolism ; Oxidative Stress ; Autophagy/genetics ; NF-kappa B/metabolism
Czasopismo naukowe
Tytuł:
Reconciling ASPP-p53 binding mode discrepancies through an ensemble binding framework that bridges crystallography and NMR data.
Autorzy:
Liu T; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Huang S; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Zhang Q; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Xia Y; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Zhang M; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Sun B; Research Center for Pharmacoinformatics, College of Pharmacy, Harbin Medical University, Harbin, China.
Pokaż więcej
Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Feb 07; Vol. 20 (2), pp. e1011519. Date of Electronic Publication: 2024 Feb 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/chemistry
Tumor Suppressor Protein p53*/chemistry
Crystallography ; Protein Binding ; Apoptosis
Czasopismo naukowe
Tytuł:
The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis.
Autorzy:
Holloway J; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK.
Seeley A; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK.
Cobbe N; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK.
Turkington RC; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK.
Longley DB; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK.
Evergren E; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, 97 Lisburn Road, BT9 7AE, Belfast, UK. .
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2024 Jan 12; Vol. 15 (1), pp. 40. Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Ubiquitin-Protein Ligases*/metabolism
Antineoplastic Agents/pharmacology ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Caspase 8/genetics ; Caspase 8/metabolism ; Cholesterol/metabolism ; Cisplatin/pharmacology ; Cisplatin/metabolism ; Cytochromes c/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Receptors, Death Domain/metabolism ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Humans
Czasopismo naukowe
Tytuł:
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral.
Autorzy:
Mei M; Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.; Chinese Institutes for Medical Research, Beijing 100069, China.
Impagnatiello MA; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
Jiao J; Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.; Chinese Institutes for Medical Research, Beijing 100069, China.
Reiser U; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
Tontsch-Grunt U; Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria.
Zhang J; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
Nicklin P; Research Beyond Borders, Boehringer Ingelheim, Biberach an der Riss, Germany.
Yu B; Research Beyond Borders, Boehringer Ingelheim, Shanghai 200120, China.
Wang Y; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China.
He Y; Research Beyond Borders, Boehringer Ingelheim, Shanghai 200120, China.
Tan X; Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China.; Chinese Institutes for Medical Research, Beijing 100069, China.
Pokaż więcej
Źródło:
Protein & cell [Protein Cell] 2024 Jan 03; Vol. 15 (1), pp. 69-75.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*
Antineoplastic Agents*/pharmacology
Apoptosis ; Antiviral Agents/pharmacology ; Mitochondrial Proteins ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Ubiquitin-proteasome pathway-mediated regulation of the Bcl-2 family: effects and therapeutic approaches.
Autorzy:
Tang GLQ; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore.
Lai JXH; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore.
Pervaiz S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Integrative Science and Engineering Programme (ISEP), NUS Graduate School (NUSGS), National University of Singapore, Singapore; NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; NUS Medicine Healthy Longevity Program, National University of Singapore, Singapore; National University Cancer Institute, National University Health System. .
Pokaż więcej
Źródło:
Haematologica [Haematologica] 2024 Jan 01; Vol. 109 (1), pp. 33-43. Date of Electronic Publication: 2024 Jan 01.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Apoptosis*
Proteasome Endopeptidase Complex*/metabolism
Humans ; Apoptosis Regulatory Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Ubiquitins/metabolism
Czasopismo naukowe
Tytuł:
Small Molecule Inhibitors Targeting the "Undruggable" Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective.
Autorzy:
Cui Q; Department of Cell and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States.
Huang C; Department of Cell and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States.
Liu JY; Department of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States.
Zhang JT; Department of Cell and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio 43614, United States.
Pokaż więcej
Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Dec 28; Vol. 66 (24), pp. 16515-16545. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Inhibitor of Apoptosis Proteins*/metabolism
Neoplasms*/metabolism
Humans ; Survivin/metabolism ; Drug Discovery ; Dimerization ; Apoptosis
Czasopismo naukowe
Tytuł:
Hsp70-Bim incoherent feedforward loop contributes to cell-fate heterogeneity and fractional killing.
Autorzy:
Yin F; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
Song T; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
Wang Z; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
Liu J; School of Life Science and Technology, Dalian University of Technology, Dalian, China.
Zhang H; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
Tang Y; School of Life Science and Technology, Dalian University of Technology, Dalian, China.
Zhang Z; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.
Pokaż więcej
Źródło:
British journal of pharmacology [Br J Pharmacol] 2024 Mar; Vol. 181 (5), pp. 659-669. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Proto-Oncogene Proteins*/metabolism
Bcl-2-Like Protein 11 ; Membrane Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2 ; Apoptosis/genetics ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Peptide-Conjugated Micelles Make Effective Mimics of the TRAIL Protein for Driving Apoptosis in Colon Cancer.
Autorzy:
Han Z; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Li Z; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Raveendran R; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Farazi S; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Cao C; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Chapman R; School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia.
Stenzel MH; Centre for Advanced Macromolecular Design, School of Chemistry, UNSW Sydney, Kensington, NSW 2052, Australia.
Pokaż więcej
Źródło:
Biomacromolecules [Biomacromolecules] 2023 Nov 13; Vol. 24 (11), pp. 5046-5057. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Apoptosis Regulatory Proteins*/pharmacology
Colonic Neoplasms*/drug therapy
Humans ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Micelles ; Ligands ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Cell Line, Tumor ; Apoptosis ; Tumor Necrosis Factor-alpha/metabolism ; Peptides/pharmacology ; Peptides/metabolism ; Carrier Proteins
Czasopismo naukowe
Tytuł:
Peritoneal Gene Transfection of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand for Tumor Surveillance and Prophylaxis.
Autorzy:
Qiu N; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.; Zhejiang Key Laboratory of Smart Biomaterials and College of Chemical and Biological Engineering, Zhejiang Univeristy, Hangzhou 310027, China.; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100090, China.
Zhang Z; Zhejiang Longcharm Bio-tech Pharma Co., Ltd. Hangzhou 310027, China.
Wei X; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xu C; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.
Jia X; Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo 315010, China.
Wang K; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Chen Y; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Wang S; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.
Su R; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.
Cen B; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Shen Y; Zhejiang Key Laboratory of Smart Biomaterials and College of Chemical and Biological Engineering, Zhejiang Univeristy, Hangzhou 310027, China.
Chen C; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100090, China.
Liu Y; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Xu X; The Center for Integrated Oncology and Precision Medicine, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.; Zhejiang University School of Medicine, Hangzhou 310058, China.; The Fourth School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Pokaż więcej
Źródło:
Nano letters [Nano Lett] 2023 Sep 13; Vol. 23 (17), pp. 7859-7868. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/pharmacology
Peritoneal Neoplasms*/genetics
Peritoneal Neoplasms*/prevention & control
Animals ; Mice ; Ligands ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/pharmacology ; Apoptosis/genetics ; Tumor Necrosis Factor-alpha/genetics ; Transfection ; TNF-Related Apoptosis-Inducing Ligand/genetics ; Receptors, TNF-Related Apoptosis-Inducing Ligand/genetics
Czasopismo naukowe
Tytuł:
Targeted Degradation of XIAP is Sufficient and Specific to Induce Apoptosis in MYCN-overexpressing High-risk Neuroblastoma.
Autorzy:
Choo Z; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Koh X; Experimental Drug Development Centre, A*STAR, Singapore.
Wong MRE; VIVA-KKH Paediatric Brain and Solid Tumour Programme, Children's Blood and Cancer Centre, KK Women's and Children's Hospital, Singapore.
Ashokan RM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ali Ahamed NSB; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Kang C; Experimental Drug Development Centre, A*STAR, Singapore.
Kuick CH; Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore.
Chang KTE; VIVA-KKH Paediatric Brain and Solid Tumour Programme, Children's Blood and Cancer Centre, KK Women's and Children's Hospital, Singapore.; Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore.; Duke NUS Medical School, Singapore.
Larisch S; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, Israel.
Loh AHP; VIVA-KKH Paediatric Brain and Solid Tumour Programme, Children's Blood and Cancer Centre, KK Women's and Children's Hospital, Singapore.; Duke NUS Medical School, Singapore.; Cell Death and Cancer Research Laboratory, Department of Human Biology and Medical Sciences, University of Haifa, Haifa, Israel.; Department of Paediatric Surgery, KK Women's and Children's Hospital, Singapore.
Chen ZX; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; VIVA-KKH Paediatric Brain and Solid Tumour Programme, Children's Blood and Cancer Centre, KK Women's and Children's Hospital, Singapore.; National University Cancer Institute, Singapore, National University Health System, Singapore.
Pokaż więcej
Źródło:
Cancer research communications [Cancer Res Commun] 2023 Nov 22; Vol. 3 (11), pp. 2386-2399.
Typ publikacji:
Journal Article
MeSH Terms:
X-Linked Inhibitor of Apoptosis Protein*/genetics
Neuroblastoma*/drug therapy
Animals ; Humans ; N-Myc Proto-Oncogene Protein/genetics ; Apoptosis ; Inhibitor of Apoptosis Proteins/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
MAP kinase ERK5 modulates cancer cell sensitivity to extrinsic apoptosis induced by death-receptor agonists.
Autorzy:
Espinosa-Gil S; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Protein Kinases in Cancer Research. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
Ivanova S; IRB Institute for Research in Biomedicine, Barcelona, Spain.; CIBERDEM, Instituto de Salud Carlos III, Madrid, Spain.
Alari-Pahissa E; University Pompeu Fabra, Barcelona, Spain.
Denizli M; Biomedical Research Group in Gynecology, Vall Hebron Institute of Research, Universitat Autònoma de Barcelona. CIBERONC, Barcelona, Spain.
Villafranca-Magdalena B; Biomedical Research Group in Gynecology, Vall Hebron Institute of Research, Universitat Autònoma de Barcelona. CIBERONC, Barcelona, Spain.
Viñas-Casas M; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Protein Kinases in Cancer Research. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
Bolinaga-Ayala I; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Protein Kinases in Cancer Research. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
Gámez-García A; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.
Faundez-Vidiella C; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Protein Kinases in Cancer Research. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
Colas E; Biomedical Research Group in Gynecology, Vall Hebron Institute of Research, Universitat Autònoma de Barcelona. CIBERONC, Barcelona, Spain.
Lopez-Botet M; University Pompeu Fabra, Barcelona, Spain.; Immunology laboratory, Dpt. of Pathology, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
Zorzano A; IRB Institute for Research in Biomedicine, Barcelona, Spain.; CIBERDEM, Instituto de Salud Carlos III, Madrid, Spain.; Departament de Bioquímica i Biomedicina Molecular, Facultat de Biología, Universitat de Barcelona, Barcelona, Spain.
Lizcano JM; Departament de Bioquímica i Biologia Molecular and Institut de Neurociències. Facultat de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain. .; Protein Kinases in Cancer Research. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain. .
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2023 Nov 02; Vol. 14 (11), pp. 715. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Signal Transduction ; Apoptosis Regulatory Proteins ; Mitogen-Activated Protein Kinases/metabolism ; Receptors, Death Domain ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; Cell Line, Tumor ; Nuclear Proteins/metabolism
Czasopismo naukowe
Tytuł:
cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.
Autorzy:
Schorn F; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.
Werthenbach JP; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.
Hoffmann M; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.
Daoud M; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.
Stachelscheid J; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.
Schiffmann LM; Faculty of Medicine and University Hospital of Cologne, Department of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Cologne, Germany.
Hildebrandt X; Faculty of Medicine and University Hospital of Cologne, Department of Translational Genomics, University of Cologne, Cologne, Germany.
Lyu SI; Faculty of Medicine and University Hospital of Cologne, Institute of Pathology and Center for Integrated Oncology (CIO) Cologne Bonn, University of Cologne, Cologne, Germany.
Peltzer N; Faculty of Medicine and University Hospital of Cologne, Department of Translational Genomics, University of Cologne, Cologne, Germany.
Quaas A; Faculty of Medicine and University Hospital of Cologne, Institute of Pathology and Center for Integrated Oncology (CIO) Cologne Bonn, University of Cologne, Cologne, Germany.
Vucic D; Department of Immunology Discovery, Genentech, South San Francisco, CA, USA.
Silke J; The Walter and Eliza Hall Institute for Medical Research, Melbourne, Vic., Australia.
Pasparakis M; Institute for Genetics, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Kashkar H; Faculty of Medicine and University Hospital of Cologne, Institute for Molecular Immunology, University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Pokaż więcej
Źródło:
The EMBO journal [EMBO J] 2023 Nov 15; Vol. 42 (22), pp. e113614. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article
MeSH Terms:
Inhibitor of Apoptosis Proteins*/genetics
Inhibitor of Apoptosis Proteins*/metabolism
Receptors, Tumor Necrosis Factor, Type I*/genetics
Receptors, Tumor Necrosis Factor, Type I*/metabolism
Animals ; Mice ; Cell Death ; Apoptosis ; Inflammation/genetics ; Inflammation/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł:
Structural insights for selective disruption of Beclin 1 binding to Bcl-2.
Autorzy:
Pan YZ; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Liang Q; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Tomchick DR; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
De Brabander JK; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Rizo J; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. .; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. .; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. .
Pokaż więcej
Źródło:
Communications biology [Commun Biol] 2023 Oct 24; Vol. 6 (1), pp. 1080. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Membrane Proteins*/metabolism
Apoptosis/physiology ; bcl-2-Associated X Protein/metabolism ; Beclin-1 ; Humans
Czasopismo naukowe
Tytuł:
Downregulation of BIRC2 hinders the progression of rheumatoid arthritis through regulating TRADD.
Autorzy:
Rao Y; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Xu S; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Lu T; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Wang Y; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Liu M; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Zhang W; Department of Rheumatology and Immunology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Pokaż więcej
Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Oct; Vol. 11 (10), pp. e978.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Arthritis, Rheumatoid*/genetics
Arthritis, Rheumatoid*/metabolism
Humans ; Down-Regulation ; Lipopolysaccharides/pharmacology ; Signal Transduction ; Inflammation ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Inhibitor of Apoptosis Proteins/genetics ; Inhibitor of Apoptosis Proteins/metabolism
Czasopismo naukowe
Tytuł:
An oral triple pill-based cocktail effectively controls acute myeloid leukemia with high translation.
Autorzy:
Li M; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Zheng S; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Gong Q; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Zhuang H; Department of Clinical Hematology and Transfusion, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China.
Wu Z; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Wang P; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Zhang X; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Xu R; Department of Hematology (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Institute of Hematology, Zhejiang University, Hangzhou 310009, China. Electronic address: .
Pokaż więcej
Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Nov; Vol. 167, pp. 115584. Date of Electronic Publication: 2023 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Leukemia, Myeloid, Acute*/metabolism
Humans ; Apoptosis Regulatory Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Proteomics-Based Discovery of First-in-Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
Autorzy:
Ji W; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Byun WS; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Lu W; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Lingang Laboratory, Shanghai, 20031, China.
Zhu X; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
Dwyer BG; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Che J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
Yuan L; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Abulaiti X; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Corsello SM; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
Zhang T; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Gray NS; Department of Chemical and Systems Biology, Chem-H and Stanford Cancer Institute, Stanford School of Medicine, Stanford University, Stanford, CA, 94305, USA.
Pokaż więcej
Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Oct 23; Vol. 62 (43), pp. e202308292. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis Regulatory Proteins*/metabolism
Lymphoma, B-Cell*
Humans ; Proteomics ; Apoptosis ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Expanded polyQ aggregates interact with sarco-endoplasmic reticulum calcium ATPase and Drosophila inhibitor of apoptosis protein1 to regulate polyQ mediated neurodegeneration in Drosophila.
Autorzy:
Maurya CK; Cytogenetics Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221005, India. Electronic address: .
Tapadia MG; Cytogenetics Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221005, India. Electronic address: .
Pokaż więcej
Źródło:
Molecular and cellular neurosciences [Mol Cell Neurosci] 2023 Sep; Vol. 126, pp. 103886. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium*/metabolism
Drosophila*/metabolism
Sarcoplasmic Reticulum Calcium-Transporting ATPases*
Inhibitor of Apoptosis Proteins*
Animals ; Apoptosis ; Calcium-Transporting ATPases ; Endoplasmic Reticulum/metabolism ; Phosphatidylinositol 3-Kinases ; Drosophila Proteins
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies