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Wyszukujesz frazę ""Apoptosis"" wg kryterium: Temat


Tytuł:
Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel.
Autorzy:
Sidler D; Institute of Pathology, Experimental Pathology, University of Bern, Bern, Switzerland.
Brockmann A
Mueller J
Nachbur U
Corazza N
Renzulli P
Hemphill A
Brunner T
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Źródło:
Oncogene [Oncogene] 2012 Sep 13; Vol. 31 (37), pp. 4095-106. Date of Electronic Publication: 2011 Dec 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Antineoplastic Agents/*pharmacology
Apoptosis Regulatory Proteins/*metabolism
Benzamides/*pharmacology
Colorectal Neoplasms/*metabolism
Glutathione S-Transferase pi/*metabolism
JNK Mitogen-Activated Protein Kinases/*metabolism
Membrane Proteins/*metabolism
Proto-Oncogene Proteins/*metabolism
Thiazoles/*pharmacology
Apoptosis Regulatory Proteins/genetics ; Bcl-2-Like Protein 11 ; Caco-2 Cells ; Cell Line, Tumor ; Down-Regulation ; Humans ; MAP Kinase Signaling System ; Membrane Proteins/genetics ; Mitochondria/metabolism ; Proto-Oncogene Proteins/genetics ; RNA Interference ; RNA, Small Interfering ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł:
Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
Autorzy:
Wilson TR; 1Drug Resistance Laboratory, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.
McEwan M
McLaughlin K
Le Clorennec C
Allen WL
Fennell DA
Johnston PG
Longley DB
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Źródło:
Oncogene [Oncogene] 2009 Jan 08; Vol. 28 (1), pp. 63-72. Date of Electronic Publication: 2008 Sep 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
CASP8 and FADD-Like Apoptosis Regulating Protein/*antagonists & inhibitors
Colorectal Neoplasms/*pathology
X-Linked Inhibitor of Apoptosis Protein/*antagonists & inhibitors
Antineoplastic Agents/therapeutic use ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; Caspase 3/metabolism ; Cell Line, Tumor ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/metabolism ; Gene Silencing ; Humans ; Mitochondria/enzymology ; Neoplasm Staging ; RNA, Small Interfering/genetics ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; X-Linked Inhibitor of Apoptosis Protein/genetics ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling.
Autorzy:
Jeon YJ; School of Biological Science/Bio-Max Institute, Seoul National University, Seoul, Korea.
Kim IK
Hong SH
Nan H
Kim HJ
Lee HJ
Masuda ES
Meyuhas O
Oh BH
Jung YK
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Źródło:
Oncogene [Oncogene] 2008 Jul 17; Vol. 27 (31), pp. 4344-52. Date of Electronic Publication: 2008 Mar 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Ribosomal Protein S6/*physiology
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; DNA, Complementary/metabolism ; HeLa Cells ; Humans ; Jurkat Cells ; Mice ; Mice, Transgenic ; Phosphorylation ; Receptors, TNF-Related Apoptosis-Inducing Ligand/metabolism ; Receptors, Tumor Necrosis Factor/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma.
Autorzy:
Teshima K; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Nara M; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Watanabe A; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Ito M; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Ikeda S; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Hatano Y; Department of Internal Medicine, Yamamoto Kumiai General Hospital, Noshiro, Japan.
Oshima K; Department of Pathology, Kurume University School of Medicine, Kurume, Japan.
Seto M; Department of Molecular Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.
Sawada K; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Tagawa H; Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
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Źródło:
Oncogene [Oncogene] 2014 Apr 24; Vol. 33 (17), pp. 2191-203. Date of Electronic Publication: 2013 May 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Lymphoma, Mantle-Cell/*metabolism
MicroRNAs/*metabolism
Neoplasm Recurrence, Local/*metabolism
Polycomb Repressive Complex 1/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; Boronic Acids/pharmacology ; Bortezomib ; Carcinogenesis/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphoma, Mantle-Cell/genetics ; Lymphoma, Mantle-Cell/pathology ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred NOD ; Mice, SCID ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Transplantation ; Neoplastic Stem Cells/metabolism ; Polycomb Repressive Complex 1/genetics ; Proto-Oncogene Mas ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Pyrazines/pharmacology ; RNA Interference ; Side-Population Cells/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł:
Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity.
Autorzy:
Arlt A; Department of Internal Medicine I, Laboratory of Molecular Gastroenterology & Hepatology, UKSH, Kiel, Germany.
Sebens S
Krebs S
Geismann C
Grossmann M
Kruse ML
Schreiber S
Schäfer H
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Źródło:
Oncogene [Oncogene] 2013 Oct; Vol. 32 (40), pp. 4825-35. Date of Electronic Publication: 2012 Oct 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Alkaloids/*pharmacology
NF-E2-Related Factor 2/*antagonists & inhibitors
Pancreatic Neoplasms/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Animals ; Cell Line, Tumor ; Etoposide/pharmacology ; Humans ; Mice ; Mice, SCID ; Pancreatic Neoplasms/enzymology ; Pancreatic Neoplasms/pathology ; Proteasome Endopeptidase Complex/genetics ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
2-deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines.
Autorzy:
Zagorodna O; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA.
Martin SM
Rutkowski DT
Kuwana T
Spitz DR
Knudson CM
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Źródło:
Oncogene [Oncogene] 2012 May 31; Vol. 31 (22), pp. 2738-49. Date of Electronic Publication: 2011 Oct 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis*
Antimetabolites/*pharmacology
Deoxyglucose/*pharmacology
Lymphoma, B-Cell/*drug therapy
Lymphoma, T-Cell/*drug therapy
Proto-Oncogene Proteins c-bcl-2/*metabolism
Animals ; Antineoplastic Combined Chemotherapy Protocols ; Apoptosis Regulatory Proteins/antagonists & inhibitors ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; Biphenyl Compounds/pharmacology ; Blotting, Western ; Caspases/metabolism ; Cell Proliferation ; Cells, Cultured ; Flow Cytometry ; Immunoprecipitation ; Lymphoma, B-Cell/metabolism ; Lymphoma, B-Cell/pathology ; Lymphoma, T-Cell/metabolism ; Lymphoma, T-Cell/pathology ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; Nitrophenols/pharmacology ; Piperazines/pharmacology ; Proto-Oncogene Proteins/antagonists & inhibitors ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Sulfonamides/pharmacology ; Thymocytes/cytology ; Thymocytes/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL).
Autorzy:
Guo Y; University of Rochester School of Medicine, NY 14642, USA.
Schoell MC
Freeman RS
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Źródło:
Oncogene [Oncogene] 2009 Apr 23; Vol. 28 (16), pp. 1864-74. Date of Electronic Publication: 2009 Mar 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*physiology
Carcinoma, Renal Cell/*pathology
Kidney Neoplasms/*pathology
Membrane Proteins/*physiology
Proto-Oncogene Proteins/*physiology
Von Hippel-Lindau Tumor Suppressor Protein/*physiology
Apoptosis Regulatory Proteins/analysis ; Apoptosis Regulatory Proteins/genetics ; Bcl-2-Like Protein 11 ; Cell Line, Tumor ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Immunoprecipitation ; Membrane Proteins/analysis ; Membrane Proteins/genetics ; Phosphorylation ; Proto-Oncogene Proteins/analysis ; Proto-Oncogene Proteins/genetics ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł:
Bax inhibitor 1 in apoptosis and disease.
Autorzy:
Robinson KS; Centre for Molecular Microbiology and Infection, Division of Cell and Molecular Biology, Imperial College London, London, UK.
Clements A
Williams AC
Berger CN
Frankel G
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Źródło:
Oncogene [Oncogene] 2011 May 26; Vol. 30 (21), pp. 2391-400. Date of Electronic Publication: 2011 Feb 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Membrane Proteins/*metabolism
Neoplasms/*metabolism
Amino Acid Sequence ; Apoptosis Regulatory Proteins/genetics ; Calcium/metabolism ; Humans ; Membrane Proteins/genetics ; Models, Biological ; Molecular Sequence Data ; Neoplasms/genetics ; Neoplasms/pathology ; Reactive Oxygen Species/metabolism ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł:
Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.
Autorzy:
Wang C; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
Youle RJ
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Źródło:
Oncogene [Oncogene] 2012 Jun 28; Vol. 31 (26), pp. 3177-89. Date of Electronic Publication: 2011 Nov 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Apoptosis*/drug effects
Proto-Oncogene Proteins c-bcl-2/*metabolism
bcl-2 Homologous Antagonist-Killer Protein/*antagonists & inhibitors
bcl-2-Associated X Protein/*metabolism
Animals ; Apoptosis Regulatory Proteins/metabolism ; Biphenyl Compounds/pharmacology ; Fluorouracil/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Knockout Techniques ; HCT116 Cells ; Humans ; Mice ; Myeloid Cell Leukemia Sequence 1 Protein ; Nitrophenols/pharmacology ; Phenotype ; Piperazines/pharmacology ; Proto-Oncogene Proteins/metabolism ; Sulfonamides/pharmacology ; bcl-2 Homologous Antagonist-Killer Protein/deficiency ; bcl-2 Homologous Antagonist-Killer Protein/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/deficiency ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł:
Deregulation of Cdk2 causes Bim-mediated apoptosis in p53-deficient tumors following actin damage.
Autorzy:
Chae HD; National Research Laboratory, Department of Microbiology, Dankook University College of Medicine, Cheonan, Korea.
Kim BM
Yun UJ
Shin DY
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Źródło:
Oncogene [Oncogene] 2008 Jul 03; Vol. 27 (29), pp. 4115-21. Date of Electronic Publication: 2008 Mar 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Apoptosis*/genetics
Tumor Suppressor Protein p53*/genetics
Actins/*metabolism
Apoptosis Regulatory Proteins/*metabolism
Colorectal Neoplasms/*enzymology
Cyclin-Dependent Kinase 2/*metabolism
Membrane Proteins/*metabolism
Proto-Oncogene Proteins/*metabolism
Actins/genetics ; Apoptosis Regulatory Proteins/genetics ; Bcl-2-Like Protein 11 ; CDC2 Protein Kinase ; Cell Line, Tumor ; Colorectal Neoplasms/genetics ; Cyclin B/genetics ; Cyclin B/metabolism ; Cyclin-Dependent Kinase 2/genetics ; Cyclin-Dependent Kinases ; Furans/pharmacology ; Gene Expression ; Genes, Dominant ; Humans ; Macrolides ; Membrane Proteins/genetics ; Mutation ; Polyploidy ; Proto-Oncogene Proteins/genetics ; Pyrans/pharmacology ; bcl-X Protein/genetics ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł:
Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway.
Autorzy:
Gallego MA; INSERM U 837, Université Lille 2, Faculté de Médecine, Jean-Pierre Aubert Research Centre, Place de Verdun, Lille, France.
Ballot C
Kluza J
Hajji N
Martoriati A
Castéra L
Cuevas C
Formstecher P
Joseph B
Kroemer G
Bailly C
Marchetti P
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Źródło:
Oncogene [Oncogene] 2008 Mar 27; Vol. 27 (14), pp. 1981-92. Date of Electronic Publication: 2007 Oct 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Drug Resistance, Neoplasm*/drug effects
Apoptosis Inducing Factor/*metabolism
Carcinoma, Non-Small-Cell Lung/*metabolism
Coumarins/*pharmacology
Heterocyclic Compounds, 4 or More Rings/*pharmacology
Isoquinolines/*pharmacology
Lung Neoplasms/*metabolism
Active Transport, Cell Nucleus/drug effects ; Apoptosis Inducing Factor/antagonists & inhibitors ; Apoptosis Inducing Factor/genetics ; Cell Line, Tumor ; Coumarins/chemistry ; DNA, Mitochondrial/metabolism ; Heterocyclic Compounds, 4 or More Rings/chemistry ; Humans ; Isoquinolines/chemistry ; Mitochondria/metabolism ; RNA, Small Interfering/pharmacology ; Reactive Oxygen Species/metabolism ; Vitamin K 3/pharmacology
Czasopismo naukowe
Tytuł:
Cancer-selective apoptotic effects of extracellular and intracellular Par-4.
Autorzy:
Shrestha-Bhattarai T; Graduate Center for Toxicology, University of Kentucky, Lexington, KY, USA.
Rangnekar VM
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Źródło:
Oncogene [Oncogene] 2010 Jul 08; Vol. 29 (27), pp. 3873-80. Date of Electronic Publication: 2010 May 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Extracellular Space/*metabolism
Intracellular Space/*metabolism
Neoplasms/*metabolism
Neoplasms/*pathology
Animals ; Apoptosis Regulatory Proteins/chemistry ; Endoplasmic Reticulum Chaperone BiP ; Humans ; Tumor Suppressor Proteins/chemistry ; Tumor Suppressor Proteins/metabolism
Czasopismo naukowe
Tytuł:
MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells.
Autorzy:
Lakshmanan I; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA.
Ponnusamy MP
Das S
Chakraborty S
Haridas D
Mukhopadhyay P
Lele SM
Batra SK
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Źródło:
Oncogene [Oncogene] 2012 Feb 16; Vol. 31 (7), pp. 805-17. Date of Electronic Publication: 2011 Jul 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Apoptosis*
Cell Proliferation*
Breast Neoplasms/*metabolism
CA-125 Antigen/*metabolism
Janus Kinase 2/*metabolism
Membrane Proteins/*metabolism
Blotting, Western ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; CA-125 Antigen/genetics ; Cell Division ; Cell Line, Tumor ; Cyclin B1/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Female ; G2 Phase ; Humans ; Immunohistochemistry ; JNK Mitogen-Activated Protein Kinases/metabolism ; Janus Kinase 2/genetics ; Membrane Proteins/genetics ; Models, Biological ; Phosphorylation ; Protein Binding ; RNA Interference ; STAT3 Transcription Factor/metabolism ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł:
Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function.
Autorzy:
Ciechomska IA; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Goemans GC
Skepper JN
Tolkovsky AM
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Źródło:
Oncogene [Oncogene] 2009 May 28; Vol. 28 (21), pp. 2128-41. Date of Electronic Publication: 2009 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Membrane Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Beclin-1 ; Cells, Cultured ; Gene Expression Regulation ; Humans ; Intracellular Space/metabolism ; Membrane Proteins/genetics ; Mice ; Protein Binding ; Proto-Oncogene Proteins c-bcl-2/genetics
Czasopismo naukowe
Tytuł:
Beclin 1: a BH3-only protein that fails to induce apoptosis.
Autorzy:
Boya P; 3D Lab (Development, Differentiation & Degeneration), Department of Cellular and Molecular Physiopathology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maetzu 9, Madrid, Spain. />Kroemer G
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Źródło:
Oncogene [Oncogene] 2009 May 28; Vol. 28 (21), pp. 2125-7. Date of Electronic Publication: 2009 Apr 27.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*metabolism
Membrane Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
Amino Acid Motifs ; Apoptosis Regulatory Proteins/genetics ; Autophagy ; Beclin-1 ; Humans ; Membrane Proteins/genetics ; Protein Binding ; Proto-Oncogene Proteins c-bcl-2/genetics
Czasopismo naukowe
Tytuł:
DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis.
Autorzy:
Olsson M; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Vakifahmetoglu H
Abruzzo PM
Högstrand K
Grandien A
Zhivotovsky B
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Źródło:
Oncogene [Oncogene] 2009 May 07; Vol. 28 (18), pp. 1949-59. Date of Electronic Publication: 2009 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
DNA Damage*
CASP8 and FADD-Like Apoptosis Regulating Protein/*metabolism
Caspase 2/*metabolism
Death Domain Receptor Signaling Adaptor Proteins/*physiology
CASP8 and FADD-Like Apoptosis Regulating Protein/chemistry ; Caspase 2/genetics ; Caspase 8/metabolism ; Enzyme Activation/drug effects ; Fluorouracil/pharmacology ; Genes, p53 ; HCT116 Cells ; Humans ; Kinetics ; RNA, Small Interfering/metabolism ; Transcriptional Activation ; Up-Regulation ; fas Receptor/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoprotein.
Autorzy:
Vogt M; Deutsches Krebsforschungszentrum, Arbeitsgruppe Molekulare Therapie Virus-assoziierter Tumore (F065), Im Neuenheimer Feld 242, Heidelberg, Germany.
Butz K
Dymalla S
Semzow J
Hoppe-Seyler F
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Źródło:
Oncogene [Oncogene] 2006 Jul 06; Vol. 25 (29), pp. 4009-15. Date of Electronic Publication: 2006 Feb 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*/drug effects
Apoptosis*/genetics
Gene Expression Regulation, Neoplastic*/drug effects
Gene Expression Regulation, Neoplastic*/genetics
DNA-Binding Proteins/*metabolism
Oncogene Proteins, Viral/*metabolism
Repressor Proteins/*metabolism
bcl-2-Associated X Protein/*metabolism
Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Caspase 3 ; Caspases/metabolism ; Cytochromes c/genetics ; Cytochromes c/metabolism ; DNA-Binding Proteins/genetics ; Enzyme Activation/genetics ; Female ; HeLa Cells ; Humans ; Mitochondria/genetics ; Mitochondria/metabolism ; Oncogene Proteins, Viral/genetics ; Protein Transport/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; RNA Interference/drug effects ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology ; Repressor Proteins/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/virology ; bcl-2-Associated X Protein/antagonists & inhibitors ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł:
DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function.
Autorzy:
Britschgi A; 1Experimental Oncology/Hematology, Department of Clinical Research, University of Bern, Bern, Switzerland.
Trinh E
Rizzi M
Jenal M
Ress A
Tobler A
Fey MF
Helin K
Tschan MP
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2008 Sep 25; Vol. 27 (43), pp. 5706-16. Date of Electronic Publication: 2008 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Apoptosis Regulatory Proteins/*genetics
Calcium-Calmodulin-Dependent Protein Kinases/*genetics
E2F1 Transcription Factor/*physiology
Kruppel-Like Transcription Factors/*physiology
Proto-Oncogene Proteins/*physiology
Apoptosis Regulatory Proteins/physiology ; Binding Sites ; Calcium-Calmodulin-Dependent Protein Kinases/physiology ; Cells, Cultured ; Death-Associated Protein Kinases ; Humans ; Kruppel-Like Factor 6 ; Promoter Regions, Genetic ; Sp1 Transcription Factor/physiology
Czasopismo naukowe

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