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Wyszukujesz frazę ""Appelman MD"" wg kryterium: Autor


Wyświetlanie 1-7 z 7
Tytuł:
Post-Translational Modifications of FXR; Implications for Cholestasis and Obesity-Related Disorders.
Autorzy:
Appelman MD; Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands.
van der Veen SW; Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands.
van Mil SWC; Center for Molecular Medicine, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2021 Sep 27; Vol. 12, pp. 729828. Date of Electronic Publication: 2021 Sep 27 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Protein Processing, Post-Translational*
Cholestasis/*pathology
Metabolic Diseases/*pathology
Obesity/*pathology
RNA-Binding Proteins/*metabolism
Animals ; Cholestasis/etiology ; Cholestasis/metabolism ; Humans ; Metabolic Diseases/etiology ; Metabolic Diseases/metabolism ; Obesity/etiology ; Obesity/metabolism ; RNA-Binding Proteins/chemistry
Czasopismo naukowe
Tytuł:
Molecular regulation of the hepatic bile acid uptake transporter and HBV entry receptor NTCP.
Autorzy:
Appelman MD; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands.
Wettengel JM; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
Protzer U; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany; German Center for Infection Research (DZIF), Munich partner site, Munich, Germany.
Oude Elferink RPJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands.
van de Graaf SFJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam University Medical Centers Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology, Metabolism (AGEM), Amsterdam, the Netherlands; Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Aug; Vol. 1866 (8), pp. 158960. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Virus Internalization*
Bile Acids and Salts/*metabolism
Hepatitis B virus/*physiology
Organic Anion Transporters, Sodium-Dependent/*metabolism
Symporters/*metabolism
Animals ; Biological Transport ; Humans
Czasopismo naukowe
Tytuł:
The Lipid Raft Component Stomatin Interacts with the Na Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake.
Autorzy:
Appelman MD; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.
Robin MJD; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.
Vogels EWM; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.
Wolzak C; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.
Vos WG; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.
Vos HR; Center for Molecular Medicine, Molecular Cancer Research Section, University Medical Center, 3584 CX Utrecht, The Netherlands.
Van Es RM; Center for Molecular Medicine, Molecular Cancer Research Section, University Medical Center, 3584 CX Utrecht, The Netherlands.
Burgering BMT; Center for Molecular Medicine, Molecular Cancer Research Section, University Medical Center, 3584 CX Utrecht, The Netherlands.
Van de Graaf SFJ; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology, Endocrinology and Metabolism, 1105 BK Amsterdam, The Netherlands.; Amsterdam UMC, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology, Endocrinology and Metabolism, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
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Źródło:
Cells [Cells] 2020 Apr 16; Vol. 9 (4). Date of Electronic Publication: 2020 Apr 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bile Acids and Salts/*metabolism
Biological Transport, Active/*genetics
Hepatocytes/*metabolism
Liver/*metabolism
Membrane Proteins/*metabolism
Organic Anion Transporters, Sodium-Dependent/*metabolism
Symporters/*metabolism
Taurocholic Acid/*metabolism
Cell Line, Tumor ; Cell Membrane/metabolism ; Chloride Channels/genetics ; Chloride Channels/metabolism ; Chromatography, Liquid ; Gene Knockdown Techniques ; Humans ; Membrane Microdomains/metabolism ; Membrane Proteins/genetics ; Organic Anion Transporters, Sodium-Dependent/genetics ; Protein Binding ; Symporters/genetics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Mechanistic insights into the inhibition of NTCP by myrcludex B.
Autorzy:
Donkers JM; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam, the Netherlands.
Appelman MD; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam, the Netherlands.
van de Graaf SFJ; Amsterdam UMC, University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism, Amsterdam, the Netherlands.; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism, Amsterdam, the Netherlands.
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Źródło:
JHEP reports : innovation in hepatology [JHEP Rep] 2019 Aug 01; Vol. 1 (4), pp. 278-285. Date of Electronic Publication: 2019 Aug 01 (Print Publication: 2019).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na -Taurocholate Cotransporting Polypeptide.
Autorzy:
Robin MJD; Amsterdam UMC University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism Amsterdam the Netherlands.
Appelman MD; Amsterdam UMC University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism Amsterdam the Netherlands.
Vos HR; Center for Molecular Medicine, Molecular Cancer Research Section University Medical Center Utrecht the Netherlands.
van Es RM; Center for Molecular Medicine, Molecular Cancer Research Section University Medical Center Utrecht the Netherlands.
Paton JC; Research Centre for Infectious Diseases, Department of Molecular and Cellular Biology University of Adelaide Adelaide Australia.
Paton AW; Research Centre for Infectious Diseases, Department of Molecular and Cellular Biology University of Adelaide Adelaide Australia.
Burgering B; Center for Molecular Medicine, Molecular Cancer Research Section University Medical Center Utrecht the Netherlands.
Fickert P; Division of Gastroenterology and Hepatology, Department of Internal Medicine Medical University of Graz Graz Austria.
Heijmans J; Amsterdam UMC, University of Amsterdam Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism Amsterdam the Netherlands.
van de Graaf SFJ; Amsterdam UMC University of Amsterdam, Tytgat Institute for Liver and Intestinal Research, Amsterdam Gastroenterology and Metabolism Amsterdam the Netherlands.; Amsterdam UMC, University of Amsterdam Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology and Metabolism Amsterdam the Netherlands.
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Źródło:
Hepatology communications [Hepatol Commun] 2018 Oct 23; Vol. 2 (12), pp. 1550-1566. Date of Electronic Publication: 2018 Oct 23 (Print Publication: 2018).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.
Autorzy:
Appelman MD; Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.
Chakraborty A; Institute of Virology, Technische Universität München / Helmholtz Zentrum München, München, Germany.; Institute for Advanced Study, Technische Universität München, München, Germany.
Protzer U; Institute of Virology, Technische Universität München / Helmholtz Zentrum München, München, Germany.; Institute for Advanced Study, Technische Universität München, München, Germany.
McKeating JA; Institute for Advanced Study, Technische Universität München, München, Germany.; Centre for Human Virology, University of Birmingham, Birmingham, United Kingdom.
van de Graaf SF; Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.
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Źródło:
PloS one [PLoS One] 2017 Jan 26; Vol. 12 (1), pp. e0170419. Date of Electronic Publication: 2017 Jan 26 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Hepatitis B/*metabolism
Organic Anion Transporters, Sodium-Dependent/*metabolism
Symporters/*metabolism
Glycosylation ; Hep G2 Cells ; Hepatitis B/virology ; Hepatitis B virus ; Humans ; Mutagenesis, Site-Directed ; Organic Anion Transporters, Sodium-Dependent/genetics ; Protein Transport/physiology ; Symporters/genetics
Czasopismo naukowe
Tytuł:
Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases.
Autorzy:
Ferraz MJ; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
Marques AR; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
Appelman MD; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
Verhoek M; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Strijland A; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
Mirzaian M; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Scheij S; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
Ouairy CM; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Lahav D; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Wisse P; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Overkleeft HS; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Boot RG; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, The Netherlands.
Aerts JM; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, The Netherlands.
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Źródło:
FEBS letters [FEBS Lett] 2016 Mar; Vol. 590 (6), pp. 716-25. Date of Electronic Publication: 2016 Mar 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acid Ceramidase/*metabolism
Fabry Disease/*metabolism
Gaucher Disease/*metabolism
Glycosphingolipids/*metabolism
Acid Ceramidase/genetics ; Acylation ; Animals ; Disease Models, Animal ; Fabry Disease/genetics ; Female ; Gaucher Disease/genetics ; Glucosylceramidase/genetics ; Glucosylceramidase/metabolism ; Glycosphingolipids/chemistry ; HEK293 Cells ; Humans ; Lysosomes/metabolism ; Male ; Mice ; Mice, Knockout ; alpha-Galactosidase/genetics ; alpha-Galactosidase/metabolism
Czasopismo naukowe
    Wyświetlanie 1-7 z 7

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