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Tytuł:
In vitro-in vivo availability of metformin hydrochloride-PLGA nanoparticles in diabetic rats in a periodontal disease experimental model.
Autorzy:
Pereira ASBF; Post-Graduation Program in Oral Science, Department of Dentistry, UFRN, Natal, Brazil.
de Souza Lima ML; Post-Graduation Program in Oral Science, Department of Dentistry, UFRN, Natal, Brazil.
da Silva-Junior AA; Postgraduate Program in Pharmaceutical Science, Federal University of Rio Grande do Norte, Natal, Brazil.
Dos Santos Silva E; Postgraduate Program in Pharmaceutical Science, Federal University of Rio Grande do Norte, Natal, Brazil.
de Araújo Júnior RF; Post-Graduation program in Functional and Structural Biology/Post-graduation program Health Science/Department of Morphology, UFRN, Natal, Brazil.
Martins AA; Department of Dentistry, UFRN, Natal, Brazil.
Alves JSF; Drug Quality Control Laboratory (LCQMed), Department of Pharmacy, UFRN, Natal, Brazil.
Oliveira AS; Drug Quality Control Laboratory (LCQMed), Department of Pharmacy, UFRN, Natal, Brazil.
De Santis Ferreira L; Drug Quality Control Laboratory (LCQMed), Department of Pharmacy, UFRN, Natal, Brazil.
de Araújo Costa ECT; Institute of Chemistry, UFRN, Natal, Brazil.
Guerra GCB; Post-Graduation Program in Biochemistry and Molecular Biology/Post-Graduation Program in Pharmaceutical Science, Department of Biophysics and Pharmacology, UFRN, Natal, Brazil.
de Medeiros CACX; Post-Graduation Program in Biochemistry and Molecular Biology/Post-Graduation Program in RENORBIO, Department of Biophysics and Pharmacology, UFRN, Natal, Brazil.
Brito GAC; Postgraduate Program in Pharmacology, Postgraduate Program in Morphology, Department of Morphology, UFC, Fortaleza, Brazil.
de Carvalho Leitao RF; Postgraduate Program in Morphology, Department of Morphology, UFC, Fortaleza, Brazil.
de Araújo AA; Post-Graduation Program Oral Science/Post-Graduation Program in Pharmaceutical Science, Department of Biophysics and Pharmacology, UFRN, Natal, Brazil.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 1576-1584.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental/*drug therapy
Hypoglycemic Agents/*administration & dosage
Metformin/*administration & dosage
Periodontal Diseases/*drug therapy
Animals ; Biological Availability ; Chromatography, High Pressure Liquid ; Dose-Response Relationship, Drug ; Drug Carriers/chemistry ; Drug Liberation ; Hypoglycemic Agents/pharmacokinetics ; Male ; Metformin/pharmacokinetics ; Nanoparticles ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Rats ; Rats, Wistar ; Streptozocin ; Tandem Mass Spectrometry ; Tissue Distribution
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Receptor AT1 Appears to Be Important for the Maintenance of Bone Mass and AT2 Receptor Function in Periodontal Bone Loss Appears to Be Regulated by AT1 Receptor.
Autorzy:
Lima MLS; Postgraduate Program in Dentistry Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Martins AA; Department of Dentistry, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Medeiros CACX; Postgraduate Program in Biochemistry and Molecular Biology, Postgraduate Program in RENORBIO, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Guerra GCB; Postgraduate Program in Biochemistry and Molecular Biology, Postgraduate Program in Pharmaceutical Science, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Santos R; Department of Physiology, Federal University of Minas Gerais, Belo Horizonte CEP 31270-901, MG, Brazil.
Bader M; Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
Pirih FQ; School of Dentistry, University of California-Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Araújo Júnior RF; Postgraduate Program in Health Sciences, Postgraduate Program in Functional and Structural Biology UFRN, Department of Morphology, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Brito GAC; Postgraduate Program in Morphofunctional Sciences, Department of Morphology, School of Medicine, Federal University of Ceará, Fortaleza CEP 60430-170, CE, Brazil.
Leitão RFC; Postgraduate Program in Morphology, Department of Morphology, Federal University of Ceará, Fortaleza CEP 60430-170, CE, Brazil.
Silva RA; Postgraduate Program in Dentistry Sciences, Department of Dentistry, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Barbosa SJA; Postgraduate Program in Pharmaceutical Science, Department of Pharmaceutical Science, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Melo RCO; Discipline of Radiology, Department of Dentistry, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
Araújo AA; Visiting Research in UCLA, Postgraduate Program in Dentistry Sciences, Postgraduate Program in Pharmaceutical Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal CEP 59072-970, RN, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 27; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Bone Loss/*metabolism
Mandibular Diseases/*metabolism
Periodontitis/*metabolism
Receptor, Angiotensin, Type 1/*metabolism
Receptor, Angiotensin, Type 2/*metabolism
Alveolar Bone Loss/genetics ; Alveolar Bone Loss/pathology ; Angiotensin II/metabolism ; Animals ; Disease Models, Animal ; Male ; Mandibular Diseases/genetics ; Mandibular Diseases/pathology ; Mice ; Mice, Knockout ; Periodontitis/genetics ; Periodontitis/pathology ; Receptor, Angiotensin, Type 1/genetics ; Receptor, Angiotensin, Type 2/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Functionalized Nanoparticles Targeting Tumor-Associated Macrophages as Cancer Therapy.
Autorzy:
He Y; Translational Nanobiomaterials and Imaging (TNI) Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
de Araújo Júnior RF; Translational Nanobiomaterials and Imaging (TNI) Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte (UFRN), Natal 59064-720, Brazil.; Cancer and Inflammation Research Laboratory (LAICI), Postgraduate Program in Functional and Structural Biology, Department of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal 59064-720, Brazil.; Percuros B.V., 2333 CL Leiden, The Netherlands.
Cruz LJ; Translational Nanobiomaterials and Imaging (TNI) Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Eich C; Translational Nanobiomaterials and Imaging (TNI) Group, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
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Źródło:
Pharmaceutics [Pharmaceutics] 2021 Oct 13; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 13.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
STAT3/NF-κB signalling disruption in M2 tumour-associated macrophages is a major target of PLGA nanocarriers/PD-L1 antibody immunomodulatory therapy in breast cancer.
Autorzy:
Cavalcante RS; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Cancer and Inflammation Research Laboratory, Department of Morphology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Ishikawa U; Cancer and Inflammation Research Laboratory, Department of Morphology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Silva ES; Postgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Silva-Júnior AA; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Postgraduate Program in Development and Technological Innovation in Medicines, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Araújo AA; Postgraduate Program in Pharmaceutical Science, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Cruz LJ; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Chan AB; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.; Biotechnology Company, Percuros B. V, Leiden, The Netherlands.
de Araújo Júnior RF; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Cancer and Inflammation Research Laboratory, Department of Morphology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
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Źródło:
British journal of pharmacology [Br J Pharmacol] 2021 Jun; Vol. 178 (11), pp. 2284-2304. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/metabolism
Breast Neoplasms*/drug therapy
Animals ; Cell Line, Tumor ; Female ; Humans ; Immunomodulation ; Mice ; NF-kappa B ; STAT3 Transcription Factor ; Tumor Microenvironment ; Tumor-Associated Macrophages
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
AT1 and AT2 Receptor Knockout Changed Osteonectin and Bone Density in Mice in Periodontal Inflammation Experimental Model.
Autorzy:
Lima MLS; Postgraduate Program in Dentistry Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, RN 59078-900, Brazil.
Medeiros CACX; Postgraduate Program in Biological Science, Postgraduate Program in RENORBIO, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, RN 59078-970, Brazil.
Guerra GCB; Postgraduate Program in Biological Science, Postgraduate Program in Pharmaceutical Science, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, RN 59078-970, Brazil.
Santos R; Department of Physiology, Federal University of Minas Gerais, Belo Horizonte, MG 31270-901, Brazil.
Bader M; Max Delbrück Center of Molecular Medicine, 13125 Berlin, Germany.
Pirih FQ; School of Dentistry, Universidad California-Los Angeles (UCLA), Los Angeles, CA 90095, USA.
Araújo Júnior RF; Post Graduate Program Functional and Structural Biology, Post Graduate Program Health Science, Department of Morphology, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal, RN 59078-970, Brazil.
Chan AB; Percuros B.V, 2333 CL Leiden, The Netherlands.; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Cruz LJ; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Brito GAC; Postgraduate Program in Pharmacology, Postgraduate Program in Morphology, Department of Morphology, Fortaleza, CE 60430-170, Brazil.
Leitão RFC; Postgraduate Program in Morphology, Department of Morphology, Fortaleza, CE 60430-170, Brazil.
Silveira EJDD; Postgraduate Program in Dentistry Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, RN 59078-900, Brazil.
Garcia VB; Postgraduate Program in Health Sciences, Cancer and Inflammation Research laboratory, Department of Morphology, Federal University of Rio Grande Norte, Natal, RN 59078-970, Brazil.
Martins AA; Department of Dentistry, Federal University of Rio Grande Norte, Natal, RN 59078-970, Brazil.
Araújo AA; Postgraduate Program in Dentistry Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, RN 59078-900, Brazil.; AV. Senador Salgado Filho, S/N, Campus Universitário, Centro de Bio-ciências, Departamento de Biofísica e Farmacologia, UFRN, Natal, RN 59078-900, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 14; Vol. 22 (10). Date of Electronic Publication: 2021 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Density/*genetics
Periodontitis/*genetics
Receptor, Angiotensin, Type 1/*genetics
Receptor, Angiotensin, Type 2/*genetics
Animals ; Disease Models, Animal ; Lipopolysaccharides/toxicity ; Male ; Mice, Knockout ; Nitric Oxide Synthase Type II/genetics ; Periodontitis/chemically induced ; Periodontitis/diagnostic imaging ; Periodontitis/pathology ; Porphyromonas gingivalis/pathogenicity ; RANK Ligand/metabolism ; X-Ray Microtomography ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effect of Dexamethasone-Loaded PLGA Nanoparticles on Oral Mucositis Induced by 5-Fluorouracil.
Autorzy:
Ribeiro SB; Post Graduate Program Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
de Araújo AA; Post Graduate Program Dental Sciences, Post Graduate Program Pharmaceutical Science, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
Oliveira MMB; Post Graduate Program Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
Santos Silva AMD; Laboratory of Pharmaceutical Technology & Biotechnology (TecBioFar), Post Graduate Program Pharmaceutical Sciences, Pharmacy Department, Federal University of Rio Grande do Norte, General Gustavo Cordeiro de Faria St, Petrópolis, Natal RN 59012-570, Brazil.
da Silva-Júnior AA; Laboratory of Pharmaceutical Technology & Biotechnology (TecBioFar), Post Graduate Program Pharmaceutical Sciences, Pharmacy Department, Federal University of Rio Grande do Norte, General Gustavo Cordeiro de Faria St, Petrópolis, Natal RN 59012-570, Brazil.
Guerra GCB; Post Graduate Program Biochemistry and Molecular Biology, Post Graduate Program Pharmaceutical Science, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
Brito GAC; Post Graduate Program Morphofunctional Sciences, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Delmiro de Farias St, Rodolfo Teófilo, Fortaleza CE 60416-030, Brazil.
Leitão RFC; Post Graduate Program Morphofunctional Sciences, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Delmiro de Farias St, Rodolfo Teófilo, Fortaleza CE 60416-030, Brazil.
Araújo Júnior RF; Post Graduate Program Functional and Structural Biology, Post Graduate Program Health Science, Department of Morphology, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
Garcia VB; Post Graduate Program Health Science, Federal University of Rio Grande do Norte, General Gustavo Cordeiro de Faria St, Petrópolis, Natal RN 59012-570, Brazil.
Vasconcelos RC; Dentist of the Municipal Health Department Natal-RN, Laranja St, Cidade Nova, Natal RN 59072-570, Brazil.
de Medeiros CACX; Post Graduate Program Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.; Post Graduate Program Biochemistry and Molecular Biology, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, 3000 Senador Salgado Filho Ave, Lagoa Nova, Natal RN 59078-970, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2021 Jan 04; Vol. 13 (1). Date of Electronic Publication: 2021 Jan 04.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Phytol-Loaded Solid Lipid Nanoparticles as a Novel Anticandidal Nanobiotechnological Approach.
Autorzy:
Lima TLC; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Souza LBFC; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte (UFRN), Gal, Gustavo Cordeiro de Faria, S/N, Petrópolis, Natal-RN 59084-100, Brazil.
Tavares-Pessoa LCS; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Santos-Silva AMD; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Cavalcante RS; Department of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Araújo-Júnior RF; Department of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Cornélio AM; Department of Morphology, Federal University of Rio Grande do Norte (UFRN), Natal-RN 59.078-970, Brazil.
Fernandes-Pedrosa MF; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
Chaves GM; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande do Norte (UFRN), Gal, Gustavo Cordeiro de Faria, S/N, Petrópolis, Natal-RN 59084-100, Brazil.
Silva-Júnior AAD; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte (UFRN), Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, Natal-RN 59072-570, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Sep 13; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 13.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chitosan Film Containing Mansoa hirsuta Fraction for Wound Healing.
Autorzy:
Rodrigues Pereira J; Department of Clinical and Toxicological Analysis, College of Pharmacy, Federal University of Rio Grande do Norte, Natal, RN 59012-570, Brazil.
Suassuna Bezerra G; Department of Pharmacy, Center of Health Sciences, Federal University of Rio Grande do Norte, Rio Grande do Norte, RN 59012-570, Brazil.
Alves Furtado A; Department of Pharmacy, Center of Health Sciences, Federal University of Rio Grande do Norte, Rio Grande do Norte, RN 59012-570, Brazil.
de Carvalho TG; Department of Morphology, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Costa da Silva V; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.
Lins Bispo Monteiro A; Department of Chemistry, Universidade Federal Rural de Pernambuco, Recife-PE 52171-900, Brazil.
Bernardo Guerra GC; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil.
de Araújo Júnior RF; Department of Morphology, Federal University of Rio Grande do Norte, Natal, RN 59072-970, Brazil.
Sant'Ana AEG; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A.C. Simões, Maceió, AL 57072-970, Brazil.
Fernandes-Pedrosa MF; Department of Pharmacy, Center of Health Sciences, Federal University of Rio Grande do Norte, Rio Grande do Norte, RN 59012-570, Brazil.
de Melo Silva D; Department of Chemistry and Exact Sciences, State University of Southwest of Bahia, Jequié, BA 45208-091, Brazil.
Pereira de Azevedo E; Graduate Program of Biotechnology, Laureate International Universities-Universidade Potiguar (UnP), Natal 59056-000, Brazil.
Sarmento Silva TM; Department of Chemistry, Universidade Federal Rural de Pernambuco, Recife-PE 52171-900, Brazil.
Araújo Moura Lemos TM; Department of Clinical and Toxicological Analysis, College of Pharmacy, Federal University of Rio Grande do Norte, Natal, RN 59012-570, Brazil.
Neves de Lima ÁA; Department of Pharmacy, Center of Health Sciences, Federal University of Rio Grande do Norte, Rio Grande do Norte, RN 59012-570, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 May 27; Vol. 12 (6). Date of Electronic Publication: 2020 May 27.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Vivo Antidepressant Effect of Passiflora edulis f. flavicarpa into Cationic Nanoparticles: Improving Bioactivity and Safety.
Autorzy:
Alves JSF; Research Group on Bioactive Natural Products (PNBio), Laboratory of Pharmacognosy, Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59.012-570, Brazil.
Silva AMDS; Laboratory of Pharmaceutical Technology & Biotechnology (TecBioFar), Graduate Program in Pharmaceutical Sciences, Pharmacy Department, Federal University of Rio Grande do Norte (UFRN), Natal 59.012-570, Brazil.
da Silva RM; Nucleus Research in Natural and Synthetic Products (NPPNS), Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14.040-903, Brazil.
Tiago PRF; Laboratory of Behavioral Pharmacology, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte (UFRN), Natal 59.078-970, Brazil.
de Carvalho TG; Graduate Program in Health Sciences, Departament of Morfology, Federal University of Rio Grande do Norte (UFRN), Natal 59.078-970, Brazil.
de Araújo Júnior RF; Graduate Program in Health Sciences, Departament of Morfology, Federal University of Rio Grande do Norte (UFRN), Natal 59.078-970, Brazil.
de Azevedo EP; Graduate Program of Biotechnology, Laureate International Universities-Universidade Potiguar (UnP), Natal 59.056-000, Brazil.
Lopes NP; Nucleus Research in Natural and Synthetic Products (NPPNS), Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14.040-903, Brazil.
Ferreira LS; Laboratory of Quality Control of Medications (LCQMed), Pharmacy Department, Federal University of Rio Grande do Norte (UFRN), Natal 59.012-570, Brazil.
Gavioli EC; Laboratory of Behavioral Pharmacology, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte (UFRN), Natal 59.078-970, Brazil.
da Silva-Júnior AA; Laboratory of Pharmaceutical Technology & Biotechnology (TecBioFar), Graduate Program in Pharmaceutical Sciences, Pharmacy Department, Federal University of Rio Grande do Norte (UFRN), Natal 59.012-570, Brazil.
Zucolotto SM; Research Group on Bioactive Natural Products (PNBio), Laboratory of Pharmacognosy, Graduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal 59.012-570, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Apr 21; Vol. 12 (4). Date of Electronic Publication: 2020 Apr 21.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of Gold Nanoparticle on 5-Fluorouracil-Induced Experimental Oral Mucositis in Hamsters.
Autorzy:
Vilar CJF; Post Graduation Program in Biological Sciences, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Ribeiro SB; Post Graduation Program in Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
de Araújo AA; Post Graduation Program in Dental Sciences/Post Graduation Program in Pharmaceutical Science/Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Guerra GCB; Post Graduation Program in Biological Sciences/Post Graduation Program in Pharmaceutical Science/Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
de Araújo Júnior RF; Post Graduation Program in Functional and Structural Biology/Post Graduation Program Health Science/Department of Morphology, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Brito GAC; Post Graduation Program in Morphofunctional Sciences/Department of Morphology, Faculty of Medicine, Federal University of Ceará, Rua Delmiro de Farias s/n, Rodolfo Teófilo, Fortaleza/CE 60416030, Brazil.
Leitão RFC; Post Graduation Program in Morphofunctional Sciences/Department of Morphology, Faculty of Medicine, Federal University of Ceará, Rua Delmiro de Farias s/n, Rodolfo Teófilo, Fortaleza/CE 60416030, Brazil.
Pontes DL; Post Graduation Program of Chemistry/Institute of Chemistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Gasparotto LHDS; Post Graduation Program of Chemistry/Institute of Chemistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Oliveira MMB; Post Graduation Program in Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Viana AD; Post Graduation Program of Chemistry/Institute of Chemistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
de Medeiros WMTQ; Post Graduation Program of Chemistry/Institute of Chemistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
Bezerra BGP; Post Graduation Program of Chemistry/Institute of Chemistry, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
de Medeiros CACX; Post Graduation Program in Biological Sciences, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.; Post Graduation Program in Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 3000, Lagoa Nova, Natal/RN 59078970, Brazil.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Mar 27; Vol. 12 (4). Date of Electronic Publication: 2020 Mar 27.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of Oxaliplatin-Loaded Poly (d,l-Lactide- co -Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer.
Autorzy:
C de S L Oliveira AL; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte (UFRN), 59078 970 Natal, RN, Brazil.; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Araújo Júnior RF; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte (UFRN), 59078 970 Natal, RN, Brazil.; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Postgraduate Program in Functional and Structural Biology, Department of Morphology, Federal University of Rio Grande do Norte (UFRN), 59078 970 Natal, RN, Brazil.
Gomes de Carvalho T; Postgraduate Program in Health Science, Federal University of Rio Grande do Norte (UFRN), 59078 970 Natal, RN, Brazil.; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
B Chan A; Percuros B.V, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Schomann T; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Percuros B.V, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
Tamburini F; Percuros B.V, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
de Geus-Oei LF; Nuclear Medicine, Department of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
J Cruz L; Translational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
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Źródło:
Pharmaceutics [Pharmaceutics] 2020 Feb 23; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 23.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Testicular characterization and spermatogenesis of the hematophagous bat Diphylla ecaudata.
Autorzy:
Silva SFMD; Department of Morphology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Silva CHS; Department of Morphology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Dias FCR; Department of General Biology, Federal University of Viçosa-UFV, Viçosa, Minas Gerais, Brazil.
Cordero-Schmidt E; Department of Ecology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Vargas-Mena JC; Department of Ecology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Silva IGMD; Department of Cell Biology, University of Brasília-UnB, Brasília, Distrito Federal, Brazil.
Báo SN; Department of Cell Biology, University of Brasília-UnB, Brasília, Distrito Federal, Brazil.
Carvalho TG; Department of Morphology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Araújo Júnior RF; Department of Morphology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
Moura CEB; Department of Animal Sciences, Federal Rural University of the Semi-Arid Region-UFERSA, Mossoró, Rio Grande do Norte, Brazil.
Melo FCSA; Department of Animal Biology, Federal University of Viçosa-UFV, Viçosa, Minas Gerais, Brazil.
Matta SLPD; Department of General Biology, Federal University of Viçosa-UFV, Viçosa, Minas Gerais, Brazil.
Morais DB; Department of Morphology, Federal University of Rio Grande do Norte-UFRN, Natal, Rio Grande do Norte, Brazil.
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Źródło:
PloS one [PLoS One] 2019 Dec 13; Vol. 14 (12), pp. e0226558. Date of Electronic Publication: 2019 Dec 13 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Spermatogenesis*
Biomarkers/*metabolism
Chiroptera/*physiology
Testis/*physiology
Animals ; Cell Nucleus/metabolism ; Leydig Cells/cytology ; Leydig Cells/metabolism ; Male ; Seminiferous Tubules/cytology ; Seminiferous Tubules/metabolism ; Sertoli Cells/cytology ; Sertoli Cells/metabolism ; Testis/anatomy & histology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Self-Assembled Benznidazole-Loaded Cationic Nanoparticles Containing Cholesterol/Sialic Acid: Physicochemical Properties, In Vitro Drug Release and In Vitro Anticancer Efficacy.
Autorzy:
Dos Santos-Silva AM; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, UFRN, Gal. Gustavo Cordeiro de Farias, Petrópolis, Natal 59.072-570, Brazil. .
de Caland LB; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, UFRN, Gal. Gustavo Cordeiro de Farias, Petrópolis, Natal 59.072-570, Brazil. .
do Nascimento EG; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, UFRN, Gal. Gustavo Cordeiro de Farias, Petrópolis, Natal 59.072-570, Brazil. .
Oliveira ALCSL; Department of Morphology, Federal University of Rio Grande do Norte, UFRN, Natal 59078-970, Brazil. .
de Araújo-Júnior RF; Department of Morphology, Federal University of Rio Grande do Norte, UFRN, Natal 59078-970, Brazil. .
Cornélio AM; Department of Morphology, Federal University of Rio Grande do Norte, UFRN, Natal 59078-970, Brazil. .
Fernandes-Pedrosa MF; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, UFRN, Gal. Gustavo Cordeiro de Farias, Petrópolis, Natal 59.072-570, Brazil. .
da Silva-Júnior AA; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, UFRN, Gal. Gustavo Cordeiro de Farias, Petrópolis, Natal 59.072-570, Brazil. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 May 11; Vol. 20 (9). Date of Electronic Publication: 2019 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Chemical Phenomena*
Drug Liberation*
Antineoplastic Agents/*pharmacology
Cholesterol/*chemistry
N-Acetylneuraminic Acid/*chemistry
Nanoparticles/*chemistry
Nitroimidazoles/*chemistry
Cations ; Cell Death/drug effects ; Drug Compounding ; HEK293 Cells ; HT29 Cells ; HeLa Cells ; Humans ; Kinetics ; Particle Size ; Spectroscopy, Fourier Transform Infrared ; Static Electricity ; Surface Properties
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats.
Autorzy:
da Silva VC; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
de Araújo AA; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
de Souza Araújo DF; Faculty of Health Sciences of Trairi, Federal University of Rio Grande do Norte, Santa Cruz 59200-000 , Brazil. daline_.
Souza Lima MCJ; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil. .
Vasconcelos RC; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
de Araújo Júnior RF; Department of Morphology, Histology and Basic Pathology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
Langasnner SMZ; Research Group on Bioactive Natural Products, Department of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil. .
de Freitas Fernandes Pedrosa M; Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, Natal 59012-570, Brazil. .
de Medeiros CACX; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
Guerra GCB; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59072-970, Brazil. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Dec 12; Vol. 19 (12). Date of Electronic Publication: 2018 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*therapeutic use
Colitis/*chemically induced
Colitis/*drug therapy
Intestines/*pathology
Ipomoea/*chemistry
Plant Extracts/*therapeutic use
Animals ; Anti-Inflammatory Agents/pharmacology ; Colitis/pathology ; Cytokines/metabolism ; Dinitrofluorobenzene/analogs & derivatives ; Female ; Gene Expression Regulation/drug effects ; Mitogen-Activated Protein Kinase 8/genetics ; Mitogen-Activated Protein Kinase 8/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Organ Size ; Oxidative Stress/drug effects ; Peroxidase/metabolism ; Plant Extracts/pharmacology ; Rats, Wistar ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metformin Hydrochloride-Loaded PLGA Nanoparticle in Periodontal Disease Experimental Model Using Diabetic Rats.
Autorzy:
Pereira ASBF; Post-Graduation Program in Oral Science, Department of Dentistry, UFRN, Natal 59072-970, Brazil. aly_.
Brito GAC; Post-Graduation Program in Pharmacology/Post-Graduation Program in Morphology, Department of Morphology, UFC, Fortaleza 60440-900, Brazil. .
Lima MLS; Post-Graduation Program in Oral Science, Department of Dentistry, UFRN, Natal 59072-970, Brazil. .
Silva Júnior AAD; Post-Graduation Program in Pharmaceutical Science/Post-Graduation Program in Health Science, Department of Pharmacology, UFRN, Natal 59072-970, Brazil. .
Silva EDS; Post-Graduation Program in Pharmaceutical Science, UFRN, Department of Pharmacology, Natal 59072-970, Brazil. emanuell_.
de Rezende AA; Post-Graduation Program in Pharmaceutical Science, UFRN, Department of Pharmacology, Natal 59072-970, Brazil. .
Bortolin RH; Post-Graduation Program in Pharmaceutical Science, UFRN, Department of Pharmacology, Natal 59072-970, Brazil. .
Galvan M; Periodontics Section, School of Dentistry, University of California, UCLA, Los Angeles, CA 90095, USA. .
Pirih FQ; Periodontics Section, School of Dentistry, University of California, UCLA, Los Angeles, CA 90095, USA. .
Araújo Júnior RF; Post-Graduation Program in Functional and Structural Biology/Post-Graduation Program Health Science, Department of Morphology, UFRN, Natal 59072-970, Brazil. .
Medeiros CACX; Post-Graduation Program Biological Science/Post-Graduation Program in RENORBIO, Department of Biophysics and Pharmacology, UFRN, Natal 59072-970, Brazil. .
Guerra GCB; Post-Graduation Program Biological Science/Post-Graduation Program in Pharmaceutical Science, Department of Biophysics and Pharmacology, UFRN, Natal 59072-970, Brazil. .
Araújo AA; Post-Graduation Program Oral Science/Post-Graduation Program in Pharmaceutical Science, Department of Biophysics and Pharmacology, UFRN, Natal 59072-970, Brazil. .; Departamento de Biofisica e Farmacologia, Av. Senador Salgado Filho, S/N, Campus Universitário, Lagoa Nova, UFRN, Natal 59072-970, Brazil. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Nov 06; Vol. 19 (11). Date of Electronic Publication: 2018 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Nanoparticles*/chemistry
Nanoparticles*/ultrastructure
Polylactic Acid-Polyglycolic Acid Copolymer*/chemistry
Hypoglycemic Agents/*administration & dosage
Metformin/*administration & dosage
Alveolar Bone Loss/diagnostic imaging ; Alveolar Bone Loss/pathology ; Animals ; Biomarkers ; Blood Glucose/drug effects ; Cytokines/metabolism ; Diabetes Mellitus, Experimental ; Disease Models, Animal ; Immunohistochemistry ; Microscopy, Atomic Force ; Particle Size ; Periodontal Diseases/diagnosis ; Periodontal Diseases/drug therapy ; Periodontal Diseases/etiology ; Periodontal Diseases/metabolism ; Rats ; X-Ray Microtomography
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Gastroprotective and Antioxidant Activity of Kalanchoe brasiliensis and Kalanchoe pinnata Leaf Juices against Indomethacin and Ethanol-Induced Gastric Lesions in Rats.
Autorzy:
de Araújo ERD; Research Group on Bioactive Natural Products, Department of Pharmacy, Federal University of Rio Grande do Norte, 59012-570 Natal, Brazil. .
Guerra GCB; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, Brazil. .
Araújo DFS; Faculty of Health Sciences of Trairi, Federal University of Rio Grande do Norte, 59200-000 Santa Cruz, Brazil. daline_.
de Araújo AA; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, Brazil. .
Fernandes JM; Research Group on Bioactive Natural Products, Department of Pharmacy, Federal University of Rio Grande do Norte, 59012-570 Natal, Brazil. .
de Araújo Júnior RF; Department of Morphology, Histology and Basic Pathology, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, Brazil. .
da Silva VC; Department of Biophysics and Pharmacology, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, Brazil. .
de Carvalho TG; Department of Morphology, Histology and Basic Pathology, Biosciences Center, Federal University of Rio Grande do Norte, 59072-970 Natal, Brazil. .
Ferreira LS; Department of Pharmacy, Federal University of Rio Grande do Norte, 59012-570 Natal, Brazil. lean_.
Zucolotto SM; Research Group on Bioactive Natural Products, Department of Pharmacy, Federal University of Rio Grande do Norte, 59012-570 Natal, Brazil. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Apr 24; Vol. 19 (5). Date of Electronic Publication: 2018 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants/*pharmacology
Ethanol/*adverse effects
Gastritis/*etiology
Gastritis/*pathology
Indomethacin/*adverse effects
Kalanchoe/*chemistry
Plant Extracts/*pharmacology
Plant Leaves/*chemistry
Protective Agents/*pharmacology
Animals ; Antioxidants/chemistry ; Chromatography, High Pressure Liquid ; Chromatography, Thin Layer ; Cytokines/metabolism ; Disease Models, Animal ; Female ; Gastric Mucosa/drug effects ; Gastric Mucosa/pathology ; Gastritis/drug therapy ; Gastritis/metabolism ; Glutathione/metabolism ; Glycoproteins/metabolism ; Immunohistochemistry ; Inflammation Mediators/metabolism ; Malondialdehyde/metabolism ; Mass Spectrometry ; Peroxidase/metabolism ; Plant Extracts/chemistry ; Protective Agents/chemistry ; Rats ; Stomach Ulcer/drug therapy ; Stomach Ulcer/etiology ; Stomach Ulcer/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters.
Autorzy:
Ribeiro SB; Post Graduation Program in Biotechnology RENORBIO, UFRN, Natal, RN, Brazil.
de Araújo AA; Post Graduation Program Public Health/Post Graduation Program in Pharmaceutical Science/Department of Biophysics and Pharmacology, UFRN, Natal, RN, Brazil.
Araújo Júnior RF; Post Graduation Program in Functional and Structural Biology/Post Graduation Program Health Science/Department of Morphology, UFRN, Natal, RN, Brazil.
Brito GAC; Post Graduation Program of Morphological Science/Department of Morphology, UFC, Fortaleza, CE, Brazil.
Leitão RC; Post Graduation Program of Morphological Science/Department of Morphology, UFC, Fortaleza, CE, Brazil.
Barbosa MM; Post Graduation Program in Biological Sciences, UFRN, Natal, RN, Brazil.
Garcia VB; Post Graduation Program Health Science, UFRN, Natal, RN, Brazil.
Medeiros AC; Post Graduation Program Health Science, Department of Surgery, UFRN, Natal, RN, Brazil.
Medeiros CACX; Post Graduation Program in Biotechnology RENORBIO/ Post Graduation Program in Biological Sciences/ Department of Biophysics and Pharmacology, UFRN, Natal, RN, Brazil.
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Źródło:
PloS one [PLoS One] 2017 Oct 23; Vol. 12 (10), pp. e0186511. Date of Electronic Publication: 2017 Oct 23 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Dexamethasone/*pharmacology
Fluorouracil/*toxicity
Stomatitis/*prevention & control
Animals ; Cricetinae ; Cyclooxygenase 2/metabolism ; Cytokines/metabolism ; Male ; Matrix Metalloproteinase 2/metabolism ; Mesocricetus ; NF-kappa B/metabolism ; Phosphorylation ; Smad Proteins/metabolism ; Stomatitis/chemically induced ; Stomatitis/metabolism ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis.
Autorzy:
Araújo AA; Department of Biophysics and Pharmacology, Post Graduation Program Public Health / Post Graduation Program in Pharmaceutical Science, UFRN, Natal, RN, Brazil.
Pereira ASBF; Post Graduation Program Public Health, UFRN, Natal, RN, Brazil.
Medeiros CACX; Department of Biophysics and Pharmacology,Post Graduation Program RENORBIO,/Post Graduation Program Biological Science, UFRN, Natal, RN, Brazil.
Brito GAC; Department of Morphology, Post Graduation Program in Morphology, UFC, Fortaleza, Ceará, Brazil.
Leitão RFC; Department of Morphology, Post Graduation Program in Morphology, UFC, Fortaleza, Ceará, Brazil.
Araújo LS; Post Graduation Program Public Health, UFRN, Natal, RN, Brazil.
Guedes PMM; Department of Microbiology and Parasitology, Post Graduation Program in Parasitary Biology/Post Guaduation Biological Science, UFRN, Natal, RN, Brazil.
Hiyari S; Section of Periodontics, School of Dentistry, University of California, UCLA, Los Angeles, California, United States of America.
Pirih FQ; Section of Periodontics, School of Dentistry, University of California, UCLA, Los Angeles, California, United States of America.
Araújo Júnior RF; Department of Morphology, Post Graduation Program in Functional and Structural Biology/ Post Graduation Program Health Science/Department of Morphology, UFRN, Natal, RN, Brazil.
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Źródło:
PloS one [PLoS One] 2017 Aug 28; Vol. 12 (8), pp. e0183506. Date of Electronic Publication: 2017 Aug 28 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Bone Loss/*drug therapy
Metformin/*pharmacology
Oxidative Stress/*drug effects
Periodontitis/*drug therapy
Alveolar Bone Loss/diagnostic imaging ; Alveolar Bone Loss/metabolism ; Alveolar Bone Loss/pathology ; Animals ; Disease Models, Animal ; Gingiva/metabolism ; Glutathione Peroxidase/metabolism ; Inflammation/diagnostic imaging ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-1beta/metabolism ; Male ; Malondialdehyde/metabolism ; Matrix Metalloproteinase 9/metabolism ; Metformin/therapeutic use ; NF-kappa B/metabolism ; Periodontitis/diagnostic imaging ; Periodontitis/metabolism ; Periodontitis/pathology ; RANK Ligand/metabolism ; Rats ; Rats, Wistar ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; X-Ray Microtomography ; Glutathione Peroxidase GPX1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Quality of Life, Integrative Community Therapy, Family Support, and Satisfaction with Health Services Among Elderly Adults with and without Symptoms of Depression.
Autorzy:
de Lima Silva V; Postgraduate Program in Pharmaceutical Science, Federal University of Rio Grande Norte, Natal, RN, Brazil.
de Medeiros CACX; Department of Biophysics and Pharmacology, Postgraduate Programmes in Biological Science and Rede Nordeste de Biotecnologia/(RENORBIO), Federal University of Rio Grande Norte, Natal, RN, Brazil.
Guerra GCB; Department of Biophysics and Pharmacology, Postgraduate Programme in Biological Science, Federal University of Rio Grande Norte, Natal, RN, Brazil.
Ferreira PHA; Department Production Engineer, Federal University of Rio Grande Norte, Natal, RN, Brazil.
de Araújo Júnior RF; Department of Morphology, Postgraduate Programme in Functional and Structural Biology and Health Science, Federal University of Rio Grande Norte, Natal, RN, Brazil.
de Araújo Barbosa SJ; Pharmaceutical Science, Department of Pharmacy, University of Rio Grande Norte, Natal, RN, Brazil.
de Araújo AA; Department of Biophysics and Pharmacology, Postgraduate Programmes in Public Health and Pharmaceutical Science, Federal University of Rio Grande Norte, Natal, RN, Brazil. .
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Źródło:
The Psychiatric quarterly [Psychiatr Q] 2017 Jun; Vol. 88 (2), pp. 359-369.
Typ publikacji:
Journal Article
MeSH Terms:
Patient Satisfaction*
Psychotherapy*
Family Relations/*psychology
Quality of Life/*psychology
Aged ; Case-Control Studies ; Cross-Sectional Studies ; Depression/psychology ; Female ; Humans ; Male ; Mental Health Services ; Patient Compliance/psychology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Low-level laser therapy (780 nm) combined with collagen sponge scaffold promotes repair of rat cranial critical-size defects and increases TGF-β, FGF-2, OPG/RANK and osteocalcin expression.
Autorzy:
de Oliveira LSS; Department of Dentistry, Post-Graduation Program in Public Health, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
de Araújo AA; Department of Biophysics and Pharmacology, Post Graduation Program in Public Health/Post Graduation Program in Pharmaceutical Science, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
de Araújo Júnior RF; Department of Morphology, Post Graduation Program in Health Science/Post Graduation Program in Functional and Structural Biology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Barboza CAG; Department of Morphology, Post-Graduation Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Borges BCD; Department of Dentistry, Post-Graduation Program in Public Health, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
da Silva JSP; Department of Dentistry, Post-Graduation Program in Public Health, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
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Źródło:
International journal of experimental pathology [Int J Exp Pathol] 2017 Apr; Vol. 98 (2), pp. 75-85. Date of Electronic Publication: 2017 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Low-Level Light Therapy*
Bone Regeneration/*physiology
Collagen/*therapeutic use
Osteocalcin/*metabolism
Skull/*surgery
Animals ; Bone Regeneration/radiation effects ; Fibroblast Growth Factor 2/metabolism ; Fluorescent Antibody Technique ; Immunohistochemistry ; Male ; Microscopy, Confocal ; Osteocalcin/analysis ; Osteoprotegerin/metabolism ; Radiography ; Random Allocation ; Rats ; Rats, Wistar ; Single-Blind Method ; Skull/diagnostic imaging ; Skull/pathology ; Skull/radiation effects ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 27

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