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    Wyświetlanie 1-6 z 6
    Tytuł:
    iPSC-derived type IV collagen α5-expressing kidney organoids model Alport syndrome.
    Autorzy:
    Hirayama R; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.; Taisho Pharmaceutical Co., Ltd., Saitama, 331-9530, Japan.
    Toyohara K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Watanabe K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Otsuki T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Araoka T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Mae SI; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Horinouchi T; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
    Yamamura T; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
    Okita K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Hotta A; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Iijima K; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.; Hyogo Prefectural Kobe Children's Hospital, Hyogo, 650-0047, Japan.; Department of Advanced Pediatric Medicine, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
    Nozu K; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
    Osafune K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan. .
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    Źródło:
    Communications biology [Commun Biol] 2023 Sep 28; Vol. 6 (1), pp. 854. Date of Electronic Publication: 2023 Sep 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Nephritis, Hereditary*/genetics
    Nephritis, Hereditary*/metabolism
    Nephritis, Hereditary*/therapy
    Induced Pluripotent Stem Cells*/metabolism
    Adolescent ; Humans ; Collagen Type IV/genetics ; Collagen Type IV/metabolism ; Kidney/metabolism ; Glomerular Basement Membrane
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cells sorted off hiPSC-derived kidney organoids coupled with immortalized cells reliably model the proximal tubule.
    Autorzy:
    Banan Sadeghian R; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan.
    Ueno R; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan.
    Takata Y; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan.
    Kawakami A; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan.
    Ma C; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan.
    Araoka T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, 606-8507, Japan.
    Takasato M; RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, 650-0047, Japan.; Graduate School of Medicine, Osaka University, Osaka, 565-0871, Japan.; Graduate School of Biostudies, Kyoto University, Kyoto, 606-8501, Japan.
    Yokokawa R; Department of Micro Engineering, Kyoto University, Kyoto, 615-8540, Japan. .
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    Źródło:
    Communications biology [Commun Biol] 2023 May 04; Vol. 6 (1), pp. 483. Date of Electronic Publication: 2023 May 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Induced Pluripotent Stem Cells*/metabolism
    Humans ; Endothelial Cells/metabolism ; Kidney/metabolism ; Organoids/metabolism ; ATP Binding Cassette Transporter, Subfamily B ; Glucose/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Development of new method to enrich human iPSC-derived renal progenitors using cell surface markers.
    Autorzy:
    Hoshina A; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
    Kawamoto T; Drug Discovery Research, Astellas Pharma Inc, Tsukuba, Ibaraki, Japan. .
    Sueta SI; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
    Mae SI; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
    Araoka T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
    Tanaka H; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.
    Sato Y; Department of Global Clinical Research, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan.
    Yamagishi Y; Drug Discovery Research, Astellas Pharma Inc, Tsukuba, Ibaraki, Japan.
    Osafune K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. .
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2018 Apr 23; Vol. 8 (1), pp. 6375. Date of Electronic Publication: 2018 Apr 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Acute Kidney Injury/*therapy
    Biomarkers/*metabolism
    Cell Separation/*methods
    Cell- and Tissue-Based Therapy/*methods
    Embryonic Stem Cells/*cytology
    Induced Pluripotent Stem Cells/*cytology
    Stem Cell Transplantation/*methods
    Acute Kidney Injury/metabolism ; Animals ; Cell Differentiation ; Cells, Cultured ; Embryonic Stem Cells/metabolism ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models.
    Autorzy:
    Ameku T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Taura D; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
    Sone M; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
    Numata T; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan.
    Nakamura M; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Shiota F; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.; Department of Artificial Kidneys, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
    Toyoda T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Matsui S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Araoka T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Yasuno T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Mae S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Kobayashi H; Department of Environmental and Health Sciences, Kyoto University School of Public Health, Kyoto 606-8501, Japan.
    Kondo N; Division of Nephrology and Dialysis, Kitano Hospital The Tazuke Kofukai Medical Research Institute, Osaka 530-8480, Japan.
    Kitaoka F; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Amano N; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Arai S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Ichisaka T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Matsuura N; Department of Environmental and Health Sciences, Kyoto University School of Public Health, Kyoto 606-8501, Japan.
    Inoue S; Department of Environmental and Health Sciences, Kyoto University School of Public Health, Kyoto 606-8501, Japan.
    Yamamoto T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8501, Japan.
    Takahashi K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Asaka I; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Yamada Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8501, Japan.
    Ubara Y; Nephrology Center and Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo 105-8470, Japan.
    Muso E; Division of Nephrology and Dialysis, Kitano Hospital The Tazuke Kofukai Medical Research Institute, Osaka 530-8480, Japan.
    Fukatsu A; Department of Artificial Kidneys, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
    Watanabe A; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto 606-8501, Japan.
    Sato Y; Clinical Research Center, Chiba University of Medicine, Chiba 260-8677, Japan.
    Nakahata T; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Mori Y; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.; Department of Technology and Ecology, Hall of Global Environmental Studies, Kyoto University, Kyoto 615-8510, Japan.
    Koizumi A; Department of Environmental and Health Sciences, Kyoto University School of Public Health, Kyoto 606-8501, Japan.
    Nakao K; Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
    Yamanaka S; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Osafune K; Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.
    Pokaż więcej
    Źródło:
    Scientific reports [Sci Rep] 2016 Jul 15; Vol. 6, pp. 30013. Date of Electronic Publication: 2016 Jul 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Induced Pluripotent Stem Cells/*metabolism
    Intracranial Aneurysm/*pathology
    Matrix Metalloproteinase 1/*blood
    Polycystic Kidney, Autosomal Dominant/*pathology
    Subarachnoid Hemorrhage/*pathology
    Aged ; Animals ; Biomarkers/blood ; Cell Differentiation ; Cells, Cultured ; DNA Methylation/genetics ; Female ; Humans ; Intracranial Aneurysm/blood ; Male ; Matrix Metalloproteinase 1/biosynthesis ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Polycystic Kidney, Autosomal Dominant/mortality ; Risk Factors ; TRPP Cation Channels/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-6 z 6

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