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Tytuł:
Cohen's Kappa Coefficient as a Measure to Assess Classification Improvement following the Addition of a New Marker to a Regression Model.
Autorzy:
Więckowska B; Department of Computer Science and Statistics, Poznan University of Medical Sciences, 60-806 Poznan, Poland.
Kubiak KB; Department of Computer Science and Statistics, Poznan University of Medical Sciences, 60-806 Poznan, Poland.
Jóźwiak P; Department of Preventive Medicine, Poznan University of Medical Sciences, 60-781 Poznan, Poland.
Moryson W; Department of Epidemiology and Hygiene, Chair of Social Medicine, Poznan University of Medical Sciences, 60-806 Poznan, Poland.
Stawińska-Witoszyńska B; Department of Epidemiology and Hygiene, Chair of Social Medicine, Poznan University of Medical Sciences, 60-806 Poznan, Poland.
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Źródło:
International journal of environmental research and public health [Int J Environ Res Public Health] 2022 Aug 17; Vol. 19 (16). Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Area Under Curve*
Biomarkers ; Cohort Studies ; Humans ; Logistic Models ; ROC Curve
Czasopismo naukowe
Szczegóły
Tytuł:
Distance- and Momentum-Based Symbolic Aggregate Approximation for Highly Imbalanced Classification.
Autorzy:
Yang DH; Advanced Institute of Convergence Technology, Suwon 16229, Korea.
Kang YS; Advanced Institute of Convergence Technology, Suwon 16229, Korea.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Jul 07; Vol. 22 (14). Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Area Under Curve*
Motion ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of the mathematical equation and trapezoidal approach for 24 h area under the plasma concentration-time curve calculation in patients who received intravenous vancomycin in an acute care setting.
Autorzy:
Chanapiwat P; Department of Pharmacy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Paiboonvong T; Department of Pharmacy Practice, College of Pharmacy, Rangsit University, Pathum Thani, Thailand.
Rattanaumpawan P; Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Montakantikul P; Division of Clinical Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Feb; Vol. 11 (1), pp. e01046.
Typ publikacji:
Journal Article
MeSH Terms:
Methicillin-Resistant Staphylococcus aureus*
Staphylococcal Infections*/drug therapy
Staphylococcal Infections*/chemically induced
Adult ; Humans ; Vancomycin ; Anti-Bacterial Agents ; Bayes Theorem ; Area Under Curve ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
VANCOmycin dose adjustments comparing trough levels to the ratio of the area under de curve to the minimum inhibitory concentration method using a BAYESian approach: A feasibility study.
Autorzy:
Bilodeau V; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.; Faculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Huot J; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.; Faculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Perreault C; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.; Faculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Haraoui LP; Department of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Delorme C; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.
Poudrette J; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.
Marsot A; Faculty of Pharmacy, Université de Montréal, Montreal, Quebec, Canada.
Crevier B; Department of Pharmacy, Centre intégré de santé et de services sociaux Montérégie-Centre, Greenfield Park, Quebec, Canada.
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Źródło:
Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2022 Dec; Vol. 47 (12), pp. 2335-2344. Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Vancomycin*
Anti-Bacterial Agents*
Humans ; Feasibility Studies ; Bayes Theorem ; Prospective Studies ; Area Under Curve ; Microbial Sensitivity Tests ; Retrospective Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Oral NLRP3 Inflammasome Inhibitor ZYIL1: First-in-Human Phase 1 Studies (Single Ascending Dose and Multiple Ascending Dose).
Autorzy:
Parmar DV; Zydus Therapeutics Inc, Pennington, New Jersey, USA.
Kansagra KA; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Momin T; Zydus Therapeutics Inc, Pennington, New Jersey, USA.
Patel HB; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Jansari GA; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Bhavsar J; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Shah C; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Patel JM; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Ghoghari A; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Barot A; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Sharma B; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Viswanathan K; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Patel HV; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
Jain MR; Zydus Research Centre, Zydus Lifesciences Limited, Ahmedabad, Gujarat, India.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 202-211. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Clinical Trial, Phase I; Journal Article
MeSH Terms:
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Humans ; Interleukin-18/metabolism ; Area Under Curve
Czasopismo naukowe
Szczegóły
Tytuł:
Effect of Severe Renal Impairment on Pharmacokinetics, Safety, and Tolerability of ACT-1014-6470, a Novel Oral Complement Factor 5a Receptor 1 Antagonist.
Autorzy:
Hammann-Hänni A; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
Kaufmann P; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
Klein G; APEX GmbH, Munich, Germany.
Schmid K; APEX GmbH, Munich, Germany.
Dingemanse J; Department of Clinical Pharmacology, Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 152-158. Date of Electronic Publication: 2022 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Factor Va*
Renal Insufficiency*
Humans ; Area Under Curve
Czasopismo naukowe
Szczegóły
Tytuł:
Pharmacokinetics, Safety, and Tolerability of the siRNA JNJ-73763989 in Healthy Chinese Adult Participants.
Autorzy:
Li H; Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing, China.; Drug Clinical Trial Center, Peking University Third Hospital, Beijing, China.
Niu X; Drug Clinical Trial Center, Peking University Third Hospital, Beijing, China.
Zhang Y; Phase I Unit of Drug Clinical Trial Center, Tianjin Fifth Central Hospital, Tianjin, China.
Zhang D; Drug Clinical Trial Center, Peking University Third Hospital, Beijing, China.
Zhang Y; Phase I Unit of Drug Clinical Trial Center, Tianjin Fifth Central Hospital, Tianjin, China.
Wang L; Clinical Pharmacology and Pharmacometrics, Janssen China Research & Development, Beijing, China.
Miao Y; Clinical Development, Janssen China Research & Development, Beijing, China.
Jiang Y; Janssen China Research & Development, Shanghai, China.
Ji J; Clinical Pharmacology and Pharmacometrics, Janssen China Research & Development, Beijing, China.
Chen Q; Clinical Development, Janssen China Research & Development, Beijing, China.
Wu X; Janssen China Research & Development, Shanghai, China.
Ediage EN; Janssen Pharmaceutica NV, Beerse, Belgium.
Kakuda TN; Janssen Research & Development, South San Francisco, California, USA.
Biermer M; Janssen Pharmaceutica NV, Beerse, Belgium.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 175-180. Date of Electronic Publication: 2022 Nov 22.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
East Asian People*
Adult ; Humans ; Male ; Female ; RNA, Small Interfering ; Dose-Response Relationship, Drug ; Double-Blind Method ; Area Under Curve
Czasopismo naukowe
Szczegóły
Tytuł:
Phase 1 Evaluation of Elezanumab (Anti-Repulsive Guidance Molecule A Monoclonal Antibody) in Healthy and Multiple Sclerosis Participants.
Autorzy:
Kalluri HV; Clinical Pharmacology and Pharmacometrics, AbbVie, North Chicago, IL.
Rosebraugh MR; Clinical Pharmacology and Pharmacometrics, AbbVie, North Chicago, IL.
Misko TP; Neuroscience, AbbVie, North Chicago, IL.
Ziemann A; Neuroscience, AbbVie, North Chicago, IL.
Liu W; Clinical Pharmacology and Pharmacometrics, AbbVie, North Chicago, IL.
Cree BAC; Weill Institute of Neurosciences, Department of Neurology, University of California, San Francisco, San Francisco, CA.
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Źródło:
Annals of neurology [Ann Neurol] 2023 Feb; Vol. 93 (2), pp. 285-296. Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Multicenter Study; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Antibodies, Monoclonal*/therapeutic use
Multiple Sclerosis*/drug therapy
Adult ; Male ; Humans ; Female ; Interleukin-10 ; Administration, Intravenous ; Healthy Volunteers ; Double-Blind Method ; Area Under Curve ; Dose-Response Relationship, Drug
Czasopismo naukowe
Szczegóły
Tytuł:
Maribavir Pharmacokinetics and Safety in Participants With Moderate Hepatic Impairment: A Phase 1, Open-Label, Single-Dose, Parallel Group Study.
Autorzy:
Song I; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Chen G; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Wu J; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
Ilic K; Takeda Development Center Americas, Inc., Lexington, Massachusetts, USA.
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Źródło:
Journal of clinical pharmacology [J Clin Pharmacol] 2023 Feb; Vol. 63 (2), pp. 250-258. Date of Electronic Publication: 2022 Oct 03.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Liver Diseases*/metabolism
Ribonucleosides*
Humans ; Area Under Curve ; Benzimidazoles
Czasopismo naukowe
Szczegóły
Tytuł:
An innovative ethosuximide granule formulation designed for pediatric use: Comparative pharmacokinetics, safety, tolerability, and palatability profile versus reference syrup.
Autorzy:
Diezi L; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Dao K; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Jullien V; Inserm U1129, Paris, France.
Roussel-Maupetit C; Advicenne Pharma, Nîmes, France.
Burton I; Clinbay, Genappe, Belgium.
André P; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Bardinet C; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Rothuizen LE; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Chtioui H; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Manso-Silvan MA; Advicenne Pharma, Nîmes, France.
Guittet C; Advicenne Pharma, Nîmes, France.
Brunner-Ferber F; Brunner Naga, Pfaeffikon, Zürich, Switzerland.
Vandenhende F; Clinbay, Genappe, Belgium.
Chiron C; Inserm U1129, Paris, France.; Inserm U1141, Paris, France.
Granier LA; Advicenne Pharma, Nîmes, France.
Buclin T; Clinical Pharmacology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Feb; Vol. 11 (1), pp. e01032.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Ethosuximide*
Adult ; Humans ; Child ; Biological Availability ; Therapeutic Equivalency ; Area Under Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Application of machine learning to predict tacrolimus exposure in liver and kidney transplant patients given the MeltDose formulation.
Autorzy:
Ponthier L; P&T, Univ. Limoges, INSERM, Limoges, France.; Department of Pediatrics, CHU Limoges, Limoges, France.
Marquet P; P&T, Univ. Limoges, INSERM, Limoges, France.; Department of Pharmacology and Toxicology, CHU Limoges, Limoges, France.
Moes DJAR; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Rostaing L; Nephrology, Hemodialysis, Apheresis and Kidney Transplantation Department, Grenoble University Hospital, Grenoble, and Grenoble Alpes University, Grenoble, France.
van Hoek B; Department of Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
Monchaud C; P&T, Univ. Limoges, INSERM, Limoges, France.; Department of Pharmacology and Toxicology, CHU Limoges, Limoges, France.
Labriffe M; P&T, Univ. Limoges, INSERM, Limoges, France.; Department of Pharmacology and Toxicology, CHU Limoges, Limoges, France.
Woillard JB; P&T, Univ. Limoges, INSERM, Limoges, France. .; Department of Pharmacology and Toxicology, CHU Limoges, Limoges, France. .
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Źródło:
European journal of clinical pharmacology [Eur J Clin Pharmacol] 2023 Feb; Vol. 79 (2), pp. 311-319. Date of Electronic Publication: 2022 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Tacrolimus*/pharmacokinetics
Kidney Transplantation*
Humans ; Immunosuppressive Agents/pharmacokinetics ; Bayes Theorem ; Area Under Curve ; Liver
Czasopismo naukowe
Szczegóły
Tytuł:
Radiomics nomogram in aiding preoperatively dilatation and curettage in differentiating type II and type I endometrial cancer.
Autorzy:
Liu XF; Department of Radiology, Jinshan Hospital, Fudan University, 201508, Shanghai, China.
Yan BC; Department of Radiology, Jinshan Hospital, Fudan University, 201508, Shanghai, China.
Li Y; Department of Radiology, Jinshan Hospital, Fudan University, 201508, Shanghai, China. Electronic address: .
Ma FH; Departments of Radiology, Obstetrics & Gynecology Hospital, Fudan University, 200090, Shanghai, China.
Qiang JW; Department of Radiology, Jinshan Hospital, Fudan University, 201508, Shanghai, China. Electronic address: .
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Źródło:
Clinical radiology [Clin Radiol] 2023 Feb; Vol. 78 (2), pp. e29-e36. Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Endometrial Neoplasms*/diagnostic imaging
Endometrial Neoplasms*/surgery
Nomograms*
Female ; Humans ; Area Under Curve ; Dilatation and Curettage ; Retrospective Studies
Czasopismo naukowe
Szczegóły
Tytuł:
3D SAACNet with GBM for the classification of benign and malignant lung nodules.
Autorzy:
Guo Z; School of Electronic and Information Engineering, Hebei University of Technology, Tianjin, 300401, China. Electronic address: .
Yang J; School of Electronic and Information Engineering, Hebei University of Technology, Tianjin, 300401, China. Electronic address: .
Zhao L; School of Electronic and Information Engineering, Hebei University of Technology, Tianjin, 300401, China. Electronic address: .
Yuan J; School of Electronic and Information Engineering, Hebei University of Technology, Tianjin, 300401, China. Electronic address: jinli_.
Yu H; Department of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, 01854, USA. Electronic address: hengyong_.
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Źródło:
Computers in biology and medicine [Comput Biol Med] 2023 Feb; Vol. 153, pp. 106532. Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/diagnosis
Solitary Pulmonary Nodule*/diagnostic imaging
Humans ; Tomography, X-Ray Computed/methods ; Area Under Curve ; Lung
Czasopismo naukowe
Szczegóły
Tytuł:
Bioequivalence and Pharmacokinetic Profiles of 2 Trimetazidine Modified-release Tablets Under Fasting and Fed Conditions in Chinese Healthy Subjects.
Autorzy:
Wang J; Department of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, People's Republic of China.; Hunan Prevention and Treatment Institute of Occupational Diseases Hospital, Changsha, People's Republic of China.; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, People's Republic of China.; Institute of Clinical Pharmacy, Central South University, Changsha, People's Republic of China.
Yang Y; Department of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, People's Republic of China.; Institute of Clinical Pharmacy, Central South University, Changsha, People's Republic of China.
Huang X; Department of National Drug Clinical Trial Research Center, Xiangya Boai Rehabilitation Hospital, Changsha, People's Republic of China.
Huang J; Department of National Drug Clinical Trial Research Center, Xiangya Boai Rehabilitation Hospital, Changsha, People's Republic of China.
Zhang B; Department of Pharmacy, The Second Xiangya Hospital of Central South University, Changsha, People's Republic of China.; Institute of Clinical Pharmacy, Central South University, Changsha, People's Republic of China.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 212-218. Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Trimetazidine*/adverse effects
Humans ; Therapeutic Equivalency ; Healthy Volunteers ; East Asian People ; Cross-Over Studies ; Area Under Curve ; Fasting ; Tablets
Czasopismo naukowe
Szczegóły
Tytuł:
A Study to Evaluate Relative Bioavailability, Food Effect, and Pharmacodynamics of Tropifexor, a Farnesoid X Receptor Agonist, in Healthy Participants.
Autorzy:
Stringer R; Novartis Institutes for BioMedical Research, PK Sciences, Basel, Switzerland.
Chen J; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Shah B; Novartis Institutes for Biomedical Research, East Hanover, New Jersey, USA.
Gu J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Zhang Y; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Prince W; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Klickstein LB; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
Woessner R; Novartis Institutes for BioMedical Research, PK Sciences, Basel, Switzerland.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 122-131. Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Food-Drug Interactions*
Humans ; Biological Availability ; Healthy Volunteers ; Cross-Over Studies ; Area Under Curve
Czasopismo naukowe
Szczegóły
Tytuł:
A single-centre, open-label, single-arm, fixed-sequence pharmacokinetic study of SHR3680 on repaglinide and bupropion in prostate cancer patients.
Autorzy:
Dai T; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Xu Z; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Huang L; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Wang Y; Department of Clinical Pharmacology, Jiangsu Hengrui Pharmaceuticals Co., Ltd., Shanghai, China.
Zeng G; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Ye M; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Liu K; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Zeng F; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Jiang S; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Han W; Urology Surgery Department, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Cao J; Department of Medicine Clinical Laboratory, The Third Xiangya Hospital of Central South University, Changsha, China.
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Źródło:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Feb; Vol. 89 (2), pp. 874-886. Date of Electronic Publication: 2022 Oct 09.
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Bupropion*
Prostatic Neoplasms*
Humans ; Male ; Area Under Curve ; Carbamates/pharmacokinetics ; Cross-Over Studies
Czasopismo naukowe
Szczegóły
Tytuł:
Diagnostic performance of artificial intelligence in multiple sclerosis: a systematic review and meta-analysis.
Autorzy:
Nabizadeh F; Neuroscience Research Group (NRG), Universal Scientific Education and Research Network (USERN), Tehran, Iran. .; School of Medicine, Iran University of Medical Sciences, Tehran, Iran. .
Ramezannezhad E; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Kargar A; Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Science, Tehran, Iran.
Sharafi AM; Student's Scientific Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Ghaderi A; Student's Scientific Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
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Źródło:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2023 Feb; Vol. 44 (2), pp. 499-517. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
Artificial Intelligence*
Multiple Sclerosis*/diagnostic imaging
Humans ; Area Under Curve ; Databases, Factual
Czasopismo naukowe
Szczegóły
Tytuł:
First-in-Human Studies of Pharmacokinetics and Safety of Utreloxastat (PTC857), a Novel 15-Lipooxygenase Inhibitor for the Treatment of Amyotrophic Lateral Sclerosis.
Autorzy:
Gao L; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Giannousis P; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Thoolen M; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Kaushik D; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Latham J; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Tansy A; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Ma J; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Johnston M; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Dali M; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Golden L; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Klein M; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Kong R; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
Trimmer J; PTC Therapeutics, Inc., South Plainfield, New Jersey, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 141-151. Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Amyotrophic Lateral Sclerosis*/drug therapy
Humans ; Area Under Curve ; Half-Life ; Double-Blind Method ; Kinetics
Czasopismo naukowe
Szczegóły
Tytuł:
Evaluation of the Pharmacokinetic Drug Interaction of Capmatinib With Itraconazole and Rifampicin and Potential Impact on Renal Transporters in Healthy Subjects.
Autorzy:
Cui X; Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA.
Chen X; Novartis Institutes for BioMedical Research, East Hanover, New Jersey, USA.
Pognan N; Novartis Pharma S.A.S, Rueil-Malmaison, France.
Sengupta T; Novartis Healthcare Pvt. Ltd., Hyderabad, Telangana, India.
Rahmanzadeh G; Novartis Pharma AG, Basel, Switzerland.
Kornberger R; Parexel International GmbH Early Phase Clinical Unit, Berlin, Germany.
Giovannini M; Global Drug Development, Novartis Services Inc., East Hanover, New Jersey, USA.
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Źródło:
Journal of clinical pharmacology [J Clin Pharmacol] 2023 Feb; Vol. 63 (2), pp. 228-238. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Itraconazole*/pharmacokinetics
Rifampin*/pharmacokinetics
Humans ; Cystatin C ; Healthy Volunteers ; Creatinine ; Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Cytochrome P-450 CYP3A/metabolism ; Drug Interactions ; Area Under Curve
Czasopismo naukowe
Szczegóły
Tytuł:
Influence of social deprivation index on in-hospital outcomes of COVID-19.
Autorzy:
Goyal P; Department of Medicine, Weill Cornell Medical College, 1320 York Avenue, New York, NY, 10021, USA.; NewYork-Presbyterian Hospital, 525 East 68th Street, New York, NY, 10065, USA.
Schenck E; Department of Medicine, Weill Cornell Medical College, 1320 York Avenue, New York, NY, 10021, USA.; NewYork-Presbyterian Hospital, 525 East 68th Street, New York, NY, 10065, USA.
Wu Y; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Zhang Y; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Visaria A; Center for Pharmacoepidemiology and Treatment Sciences, Rutgers Institute for Health, Health Care Policy, and Aging Research, New Brunswick, NJ, USA.
Orlander D; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Xi W; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Díaz I; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Morozyuk D; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Weiner M; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.
Kaushal R; Department of Medicine, Weill Cornell Medical College, 1320 York Avenue, New York, NY, 10021, USA.; NewYork-Presbyterian Hospital, 525 East 68th Street, New York, NY, 10065, USA.; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA.; Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA.
Banerjee S; Department of Population Health Sciences, Weill Cornell Medical College, 425 East 61St Street, New York, NY, 10065, USA. .; New York, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 31; Vol. 13 (1), pp. 1746. Date of Electronic Publication: 2023 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Adult ; Humans ; Area Under Curve ; Health Status ; Hospitals ; Social Deprivation
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 26768

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