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Wyświetlanie 1-13 z 13
Tytuł :
Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes.
Autorzy :
Sharma A; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Maurya CK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Arha D; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India.
Rai AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Singh S; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India.
Varshney S; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India; Division of Pharmacology, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Schertzer JD; Department of Biochemistry and Biomedical Sciences and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton L8N3Z5, Canada.
Tamrakar AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2019 Jan; Vol. 1865 (1), pp. 136-146. Date of Electronic Publication: 2018 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipocytes/*metabolism
Diglycerides/*metabolism
Inflammation/*metabolism
Interleukin-1 Receptor-Associated Kinases/*metabolism
Lipolysis/*physiology
Nod1 Signaling Adaptor Protein/*metabolism
Protein Kinase C-delta/*metabolism
3T3-L1 Cells ; Animals ; Chemokine CCL2/metabolism ; Cytokines/metabolism ; Gene Knockdown Techniques ; Immunity, Innate ; Insulin Resistance ; Interleukin-1 Receptor-Associated Kinases/genetics ; Interleukin-18/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6 ; Mice ; NF-kappa B/metabolism ; Obesity ; Peptidoglycan/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells.
Autorzy :
Maurya CK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Arha D; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Rai AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Kumar SK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Pandey J; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Avisetti DR; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Kalivendi SV; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
Klip A; Program in Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada.
Tamrakar AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2015 Dec; Vol. 89, pp. 158-69. Date of Electronic Publication: 2015 Sep 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Insulin Resistance*
Oxidative Stress*
Mitochondria/*pathology
Muscle Fibers, Skeletal/*pathology
Muscle, Skeletal/*pathology
Nod2 Signaling Adaptor Protein/*metabolism
Animals ; Apoptosis ; Blotting, Western ; Cells, Cultured ; Immunoenzyme Techniques ; Membrane Potential, Mitochondrial ; Mitochondria/metabolism ; Muscle Fibers, Skeletal/metabolism ; Muscle, Skeletal/metabolism ; Nod2 Signaling Adaptor Protein/genetics ; Phosphorylation ; RNA, Messenger/genetics ; Rats ; Reactive Oxygen Species/metabolism ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction
Czasopismo naukowe
    Wyświetlanie 1-13 z 13

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