Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes.
Autorzy :
Sharma A; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Maurya CK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Arha D; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India. Rai AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Singh S; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India. Varshney S; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India; Division of Pharmacology, CSIR-Central Drug Research Institute, Lucknow 226031, India. Schertzer JD; Department of Biochemistry and Biomedical Sciences and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton L8N3Z5, Canada. Tamrakar AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 201002, India. Electronic address: .
NOD2 activation induces oxidative stress contributing to mitochondrial dysfunction and insulin resistance in skeletal muscle cells.
Autorzy :
Maurya CK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Arha D; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Rai AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Kumar SK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Pandey J; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Avisetti DR; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. Kalivendi SV; Centre for Chemical Biology, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. Klip A; Program in Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada. Tamrakar AK; Division of Biochemistry, CSIR-Central Drug Research Institute, Lucknow 226031, India. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2015 Dec; Vol. 89, pp. 158-69. Date of Electronic Publication: 2015 Sep 21.
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