- Tytuł:
- Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C.
- Autorzy:
- Źródło:
- BMC gastroenterology [BMC Gastroenterol] 2014 Jul 27; Vol. 14, pp. 131. Date of Electronic Publication: 2014 Jul 27.
- Typ publikacji:
- Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use
Cytokines/*immunology
Hepatitis C, Chronic/*drug therapyLiver /*pathology
Pyridones/*therapeutic use
RNA, Messenger/*genetics
Aged ; Cohort Studies ; FattyLiver /pathology ; Female ; Gene Expression ; Hepatitis C, Chronic/genetics ; Hepatitis C, Chronic/immunology ; Humans ; Interleukin-6/immunology ;Liver Cirrhosis/pathology ; Male ; Middle Aged ; Receptor, Cannabinoid, CB1/genetics ; Receptor, Cannabinoid, CB2/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Transforming Growth Factor beta1/immunology ; Treatment Outcome ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe