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Tytuł:
Aromatase Inhibitors as a Promising Direction for the Search for New Anticancer Drugs.
Autorzy:
Janowska S; Department of Pathobiochemistry and Interdisciplinary Applications of Ion Chromatography, Biomedical Sciences, Medical University of Lublin, 1 Chodzki Street, 20-093 Lublin, Poland.
Holota S; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.
Lesyk R; Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.
Wujec M; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 10; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aromatase Inhibitors*/pharmacology
Aromatase Inhibitors*/therapeutic use
Aromatase*
Female ; Male ; Humans ; Estrogens ; Adipose Tissue ; Androgens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of Aromatase Inhibitor Letrozole on the Placenta of Adult Albino Rats: A Histopathological, Immunohistochemical, and Biochemical Study.
Autorzy:
Alabiad MA; Department of Pathology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Elhasadi I; Department of Pathology, Faculty of Medicine, University of Benghazi, Benghazi, Libya.
Alnasser SM; Department of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim, University, Buraydah, Saudi Arabia.
Alorini M; Department of Basic Medical Sciences, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah, Kingdom of Saudi Arabia.
Alshaikh ABA; Department of Obstetrics and Gynecology, College of Medicine, Jouf University, Sakaka, Kingdom of Saudi Arabia.
Jaber FA; Department of Biology, College of Science, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
Shalaby AM; Department of Histology and Cell Biology, School of Medicine, Tanta University, Tanta, Egypt.
Samy W; Department of Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Heraiz AI; Department of Gynecology and Obstetrics, School of Medicine, Zagazig University, Zagazig, Egypt.
Mohammed Albakoush KM; Department of Anatomy and Embryology, Faculty of Medicine, Alasmarya Islamic University, Zliten, Libya.
Khairy DA; Department of Pathology, School of Medicine, Beni-Suef University, Beni-Suef, Egypt.
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Źródło:
Iranian journal of medical sciences [Iran J Med Sci] 2024 Jan 01; Vol. 49 (1), pp. 46-56. Date of Electronic Publication: 2024 Jan 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/pharmacology
Letrozole*/pharmacology
Placenta*/drug effects
Animals ; Female ; Pregnancy ; Rats ; Receptors, Estrogen ; Vascular Endothelial Growth Factor A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of dietary aromatase inhibitors on masculinization of rosy barb (Pethia conchonius): Evidence from growth, coloration and gonado-physiological changes.
Autorzy:
Lal J; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Biswas P; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Singh SK; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Debbarma R; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Deb S; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Yadav NK; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
Patel AB; Department of Aquaculture, College of Fisheries, Central Agricultural University, Lembucherra, Tripura, India.
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Źródło:
PloS one [PLoS One] 2023 Nov 03; Vol. 18 (11), pp. e0287934. Date of Electronic Publication: 2023 Nov 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aromatase Inhibitors*/pharmacology
Cyprinidae*
Animals ; Male ; Letrozole/pharmacology ; Methyltestosterone/pharmacology ; Diet
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity.
Autorzy:
Maghraby MT; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, New Valley University, New Valley 72511, Egypt.
Mazyad Almutairi T; Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Bräse S; Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
Salem OIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Youssif BGM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Sheha MM; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, New-Assiut 71684, Egypt.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Oct 14; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/chemistry
Antineoplastic Agents*/chemistry
Aromatase ; Molecular Docking Simulation ; Structure-Activity Relationship ; Erlotinib Hydrochloride/pharmacology ; Cell Line, Tumor ; Triazoles/chemistry ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A case of aromatase inhibitor-induced alopecia successfully treated with low-dose oral minoxidil.
Autorzy:
Lee YY; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Sung YK; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Hong D; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Jung KE; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Seo YJ; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
Lee Y; Department of Dermatology, School of Medicine, Chungnam National University, Daejeon, Korea.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2023 Aug; Vol. 22 (8), pp. 2374-2375. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Case Reports; Letter
MeSH Terms:
Aromatase Inhibitors*/adverse effects
Minoxidil*/administration & dosage
Minoxidil*/therapeutic use
Humans ; Administration, Topical ; Alopecia/chemically induced ; Alopecia/drug therapy ; Treatment Outcome
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Systematic review of economic evaluations of aromatase inhibitors in estrogen receptor-positive breast cancer: quality evaluation.
Autorzy:
Althuwaibi MF; College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, 11671, Saudi Arabia. .; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom. .
Fernandez-Garcia C; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Hayes L; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
McNally R; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Coughlan D; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
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Źródło:
BMC health services research [BMC Health Serv Res] 2023 Jun 26; Vol. 23 (1), pp. 689. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Systematic Review; Journal Article
MeSH Terms:
Aromatase Inhibitors*/therapeutic use
Breast Neoplasms*/drug therapy
Female ; Humans ; Cost-Benefit Analysis ; Receptors, Estrogen/genetics ; Tamoxifen/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Real-World Use of Highly Sensitive Liquid Biopsy Monitoring in Metastatic Breast Cancer Patients Treated with Endocrine Agents after Exposure to Aromatase Inhibitors.
Autorzy:
Fuentes-Antrás J; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.; Experimental Therapeutics Unit, Hospital Clínico San Carlos, IDISSC and CIBERONC, 28040 Madrid, Spain.
Martínez-Rodríguez A; Molecular Oncology Laboratory, IdISSC, 28040 Madrid, Spain.
Guevara-Hoyer K; Department of Clinical Immunology, Hospital Clínico San Carlos, IdISSC, 28040 Madrid, Spain.; Cancer Immunomonitoring and Immune-Mediated Diseases Unit, Hospital Clínico San Carlos, IdISSC, 28040 Madrid, Spain.
López-Cade I; Experimental Therapeutics Unit, Hospital Clínico San Carlos, IDISSC and CIBERONC, 28040 Madrid, Spain.; Molecular Oncology Laboratory, IdISSC, 28040 Madrid, Spain.
Lorca V; Molecular Oncology Laboratory, IdISSC, 28040 Madrid, Spain.
Pascual A; Department of Pathology, Hospital Clínico San Carlos, 28040 Madrid, Spain.
de Luna A; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Ramírez-Ruda C; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Swindell J; Medical Affairs Division, Sysmex Inostics, Inc., Baltimore, MD 21205, USA.
Flores P; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Lluch A; INCLIVA Research Institute, Hospital Clínico Universitario de Valencia, 46010 Valencia, Spain.
Cescon DW; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5S A18, Canada.
Pérez-Segura P; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Ocaña A; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.; Experimental Therapeutics Unit, Hospital Clínico San Carlos, IDISSC and CIBERONC, 28040 Madrid, Spain.
Jones F; Medical Affairs Division, Sysmex Inostics, Inc., Baltimore, MD 21205, USA.
Moreno F; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
García-Barberán V; Molecular Oncology Laboratory, IdISSC, 28040 Madrid, Spain.
García-Sáenz JÁ; Department of Medical Oncology, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 13; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 13.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/therapeutic use
Breast Neoplasms*/blood
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Female ; Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Class I Phosphatidylinositol 3-Kinases/genetics ; Liquid Biopsy ; Phosphatidylinositol 3-Kinases ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of CDK4/6 Inhibitors on Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) in the Adjuvant Setting.
Autorzy:
Skafida E; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Andrikopoulou A; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Terpos E; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Markellos C; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Moustafa S; Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece.
Pectasides D; Oncology Section, Second Department of Internal Medicine, Hippokration Hospital, Athens, Greece.
Dimopoulos MA; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Zagouri F; Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens, Greece.
Vassilopoulos D; Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, National and Kapodistrian University of Athens School of Medicine, Hippokration General Hospital, Athens, Greece.
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Źródło:
The breast journal [Breast J] 2023 May 31; Vol. 2023, pp. 3614296. Date of Electronic Publication: 2023 May 31 (Print Publication: 2023).
Typ publikacji:
Systematic Review; Journal Article; Review
MeSH Terms:
Aromatase Inhibitors*/adverse effects
Breast Neoplasms*/pathology
Humans ; Female ; Arthralgia/chemically induced ; Arthralgia/drug therapy ; Cyclin-Dependent Kinase 4
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of using adjuvant aromatase inhibitors on cognitive functions in postmenopausal women with hormone receptor-positive breast cancer.
Autorzy:
Ilhan RG; Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Ilhan Y; Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Goksu SS; Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Tatli AM; Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Coskun HS; Department of Medical Oncology, Akdeniz University Faculty of Medicine, Antalya, Turkey.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Apr; Vol. 19 (Supplement), pp. S0.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/adverse effects
Aromatase Inhibitors*/therapeutic use
Breast Neoplasms*/drug therapy
Cognition*/drug effects
Female ; Humans ; Chemotherapy, Adjuvant/adverse effects ; Estrogens ; Postmenopause ; Tamoxifen/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment.
Autorzy:
Gobbi S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Martini S; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy.
Rozza R; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy.
Spinello A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.
Caciolla J; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Rampa A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Belluti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Zaffaroni N; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy.
Magistrato A; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy.
Bisi A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/enzymology
Breast Neoplasms*/metabolism
Aromatase Inhibitors*/chemical synthesis
Aromatase Inhibitors*/chemistry
Aromatase Inhibitors*/pharmacology
Flavonoids*/chemical synthesis
Flavonoids*/chemistry
Flavonoids*/pharmacology
Drug Design*
Estrogen Receptor alpha*/antagonists & inhibitors
Estrogen Receptor alpha*/chemistry
Estrogen Receptor alpha*/metabolism
Aromatase*/chemistry
Aromatase*/metabolism
Humans ; Female ; Molecular Dynamics Simulation ; Thermodynamics ; Inhibitory Concentration 50 ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis.
Autorzy:
Bérczi, Bálint (AUTHOR)
Farkas, Nelli (AUTHOR)
Hegyi, Péter (AUTHOR)
Tóth, Barbara (AUTHOR)
Csupor, Dezső (AUTHOR)
Németh, Balázs (AUTHOR)
Lukács, Anita (AUTHOR)
Czumbel, László Márk (AUTHOR)
Kerémi, Beáta (AUTHOR)
Kiss, István (AUTHOR)
Szabó, Andrea (AUTHOR)
Varga, Gábor (AUTHOR)
Gerber, Gábor (AUTHOR)
Gyöngyi, Zoltán (AUTHOR)
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Źródło:
Journal of Clinical Medicine. Mar2024, Vol. 13 Issue 6, p1818. 20p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme.
Autorzy:
Adon T; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.
Shanmugarajan D; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.
Ather H; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Ansari SMA; Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Hani U; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.
Madhunapantula SV; Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India.; Special Interest Group in Cancer Biology and Cancer Stem Cells, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India.
Honnavalli YK; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru 570015, Karnataka, India.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 08; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/pharmacology
Aromatase Inhibitors*/chemistry
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Humans ; Female ; Aromatase ; Molecular Docking Simulation ; Anastrozole/therapeutic use ; Molecular Dynamics Simulation ; Enzyme Inhibitors/therapeutic use ; Cyclin-Dependent Kinase 4
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation.
Autorzy:
De Luca M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Rizzuti B; CNR-NANOTEC, SS Rende (CS), Department of Physics, University of Calabria, Rende, Italy.; Institute for Biocomputation and Physics of Complex Systems (BIFI), Joint Unit GBsC-CSIC-BIFI, University of Zaragoza, Zaragoza, Spain.
Ioele G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Ragno G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Garofalo A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
Grande F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1600-1609.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase*
Aromatase Inhibitors*/chemistry
Aromatase Inhibitors*/pharmacology
Chemometrics ; Female ; Humans ; Kinetics ; Letrozole/pharmacology ; Molecular Docking Simulation ; Nitriles/chemistry ; Nitriles/pharmacology ; Triazoles/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular and clinical effects of aromatase inhibitor therapy on skeletal muscle function in early-stage breast cancer.
Autorzy:
Seibert TA; Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Shi L; Department of Endocrine Neoplasia and Hormonal Disorders, MD Anderson Cancer Center, Houston, TX, 77030, USA.
Althouse S; Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Hoffman R; Department of Kinesiology, Indiana University School of Health & Human Sciences, Indianapolis, IN, 46202, USA.
Schneider BP; Division of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, 535 Barnhill Dr. RT 472, Indianapolis, IN, 46202, USA.
Russ KA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Altherr CA; Indiana Center for Musculoskeletal Health, Clinical Research Center, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Warden SJ; Department of Physical Therapy, Indiana University School of Health & Human Sciences, Indianapolis, IN, 46202, USA.
Guise TA; Department of Kinesiology, Indiana University School of Health & Human Sciences, Indianapolis, IN, 46202, USA.
Coggan AR; Department of Kinesiology, Indiana University School of Health & Human Sciences, Indianapolis, IN, 46202, USA.
Ballinger TJ; Division of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, 535 Barnhill Dr. RT 472, Indianapolis, IN, 46202, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 10; Vol. 14 (1), pp. 1029. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Ryanodine Receptor Calcium Release Channel*
Breast Neoplasms*/drug therapy
Female ; Humans ; Aromatase Inhibitors/pharmacology ; Aromatase Inhibitors/therapeutic use ; Muscle, Skeletal ; Walking
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In-silico and in-vitro study reveals ziprasidone as a potential aromatase inhibitor against breast carcinoma.
Autorzy:
Sahu, Ankita (AUTHOR)
Ahmad, Shaban (AUTHOR)
Imtiyaz, Khalid (AUTHOR)
Kizhakkeppurath Kumaran, Ajeeshkumar (AUTHOR)
Islam, Mojahidul (AUTHOR)
Raza, Khalid (AUTHOR)
Easwaran, Murugesh (AUTHOR)
Kurukkan Kunnath, Asha (AUTHOR)
Rizvi, Moshahid A. (AUTHOR)
Verma, Saurabh (AUTHOR)
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Źródło:
Scientific Reports. 11/18/2023, Vol. 13 Issue 1, p1-17. 17p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The effect of exercise training on endothelial function in postmenopausal women with breast cancer under aromatase inhibitor therapy.
Autorzy:
Mayr B; Institute of Sports Medicine, Prevention and Rehabilitation and Research Institute of Molecular Sports Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Reich B; Institute of Sports Medicine, Prevention and Rehabilitation and Research Institute of Molecular Sports Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Greil R; Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectious Diseases, Rheumatology, Oncologic Center, Paracelsus Medical University Salzburg, Salzburg, Austria.; Salzburg Cancer Research Institute with Laboratory of Immunological and Molecular Cancer Research and Center for Clinical Cancer and Immunology Trials, Salzburg, Austria.; Cancer Cluster Salzburg, Salzburg, Austria.
Niebauer J; Institute of Sports Medicine, Prevention and Rehabilitation and Research Institute of Molecular Sports Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
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Źródło:
Cancer medicine [Cancer Med] 2022 Dec; Vol. 11 (24), pp. 4946-4953. Date of Electronic Publication: 2022 May 18.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aromatase Inhibitors*/therapeutic use
Breast Neoplasms*/drug therapy
Female ; Humans ; Postmenopause ; Exercise ; Exercise Therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The effect of aromatase inhibitors against possible testis toxicity in pembrolizumab treated rats.
Autorzy:
Türkmen NB; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Inonu University, Malatya, Turkey.
Çiftçi O; Faculty of Medicine, Department of Medicinal Pharmacology, Pamukkale University, Denizli, Turkey.
Taşlıdere A; Faculty of Medicine, Histology and Embryology Department, Inonu University, Malatya, Turkey.
Aydın M; Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology, Firat University, Elazig, Turkey.
Eke BC; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara University, Ankara, Turkey.
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Źródło:
Andrologia [Andrologia] 2022 Nov; Vol. 54 (10), pp. e14557. Date of Electronic Publication: 2022 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antioxidants*/pharmacology
Aromatase Inhibitors*/pharmacology
Testis*
Anastrozole/pharmacology ; Animals ; Antibodies, Monoclonal, Humanized/toxicity ; Aromatase ; Catalase/pharmacology ; Glutathione ; Glutathione Peroxidase ; Male ; Polyphenols/pharmacology ; Programmed Cell Death 1 Receptor/metabolism ; Rats ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Semen ; Sperm Motility ; Superoxide Dismutase/metabolism ; Testosterone ; Thiobarbituric Acid Reactive Substances
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Feasibility of point of care testing for prevention and management of breast cancer therapy associated comorbidities in 6 African countries: short communication.
Autorzy:
Milambo JPM; Department of Public health, Faculty of Medicine and Health Sciences, University of Free State, Florence Street, 7530, Bellville, Cape Town, South Africa. .
Ndirangu J; Department of Public health, Faculty of Medicine and Health Sciences, University of Free State, Florence Street, 7530, Bellville, Cape Town, South Africa.
Nyasulu PS; University of Stellenbosch, Stellenbosch, South Africa.
Akudugu JM; University of Stellenbosch, Stellenbosch, South Africa.
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Źródło:
BMC research notes [BMC Res Notes] 2022 Oct 22; Vol. 15 (1), pp. 328. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase Inhibitors*/adverse effects
Breast Neoplasms*/diagnosis
Breast Neoplasms*/drug therapy
Humans ; Female ; C-Reactive Protein ; Calcium ; Feasibility Studies ; Obesity/complications ; Obesity/epidemiology ; Point-of-Care Testing ; Homocysteine ; Ferritins ; Inflammation Mediators
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multiple musculoskeletal abnormalities in a woman with breast cancer treated with aromatase inhibitor.
Autorzy:
Zardi EM; Head of Internistic Ultrasound Service. Hospitalist consultant for Thoracic and Vascular Surgery Units. Department of Medicine and Surgery. Fondazione Policlinico Universitario Campus Bio-Medico. Via Alvaro del Portillo, 200. 00128 Rome. Italy.. .
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Źródło:
Medical ultrasonography [Med Ultrason] 2023 Dec 27; Vol. 25 (4), pp. 483-484.
Typ publikacji:
Letter
MeSH Terms:
Breast Neoplasms*/diagnostic imaging
Breast Neoplasms*/drug therapy
Musculoskeletal Abnormalities*
Musculoskeletal Diseases*
Female ; Humans ; Aromatase Inhibitors/adverse effects
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 7343

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