Temat: "Aryl Hydrocarbon Hydroxylases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pharmacogenomics of poor drug metabolism in Greyhounds: Cytochrome P450 (CYP) 2B11 genetic variation, breed distribution, and functional characterization.
Autorzy:: Martinez SE; Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America. s_.
Andresen MC; Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America.
Zhu Z; Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America.
Papageorgiou I; Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America.; Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, Diabetes Institute, University of Florida, Gainesville, Florida, United States of America.
Court MH; Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine (PrIMe), Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Jan 09; Vol. 10 (1), pp. 69. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Variation*
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P450 Family 2/*metabolism
Pharmacogenetics/*methods
Steroid Hydroxylases/*metabolism
3' Untranslated Regions ; Alleles ; Anesthetics, Intravenous/metabolism ; Animals ; Aryl Hydrocarbon Hydroxylases/genetics ; Breeding ; Cytochrome P450 Family 2/genetics ; Dogs ; Gene Frequency ; Haplotypes ; Linkage Disequilibrium ; Liver/enzymology ; Liver/metabolism ; Microsomes, Liver/metabolism ; Propofol/metabolism ; RNA Splicing ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/isolation & purification ; Steroid Hydroxylases/genetics

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Tytuł:: Daikenchuto (TU-100) alters murine hepatic and intestinal drug metabolizing enzymes in an in vivo dietary model: effects of gender and withdrawal.
Autorzy:: Nobutani K; Department of Medicine, Knapp Center for Biomedical Center, The University of Chicago, Chicago, Illinois.
Miyoshi J; Department of Medicine, Knapp Center for Biomedical Center, The University of Chicago, Chicago, Illinois.
Musch MW; Department of Medicine, Knapp Center for Biomedical Center, The University of Chicago, Chicago, Illinois.
Nishiyama M; Tsumura Research Laboratories, Tsumura & Co., Ami, Ibaraki, Japan.
Watanabe J; Tsumura Research Laboratories, Tsumura & Co., Ami, Ibaraki, Japan.
Kaneko A; Tsumura Research Laboratories, Tsumura & Co., Ami, Ibaraki, Japan.
Yamamoto M; Tsumura Research Laboratories, Tsumura & Co., Ami, Ibaraki, Japan.
Yoshida M; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Kono T; Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital, Sapporo, Hokkaido, Japan.; Division of Gastroenterologic and General Surgery, Department of Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Jeong H; Departments of Pharmacy Practice and Biopharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago, Illinois.
Chang EB; Department of Medicine, Knapp Center for Biomedical Center, The University of Chicago, Chicago, Illinois.; Pokaż więcej
Źródło:: Pharmacology research & perspectives [Pharmacol Res Perspect] 2017 Oct; Vol. 5 (5).
Typ publikacji:: Journal Article
MeSH Terms:: ATP Binding Cassette Transporter, Subfamily B/*genetics
Aryl Hydrocarbon Hydroxylases/*genetics
Cytochrome P-450 CYP3A/*genetics
Cytochrome P450 Family 2/*genetics
Intestines/*enzymology
Liver/*enzymology
Membrane Proteins/*genetics
Plant Extracts/*adverse effects
Steroid Hydroxylases/*genetics
ATP Binding Cassette Transporter, Subfamily B/metabolism ; Animals ; Aryl Hydrocarbon Hydroxylases/metabolism ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P450 Family 2/metabolism ; Dietary Supplements/adverse effects ; Dose-Response Relationship, Drug ; Female ; Gene Expression Regulation, Enzymologic/drug effects ; Intestines/drug effects ; Liver/drug effects ; Male ; Membrane Proteins/metabolism ; Mice ; Models, Animal ; Panax ; Sex Factors ; Steroid Hydroxylases/metabolism ; Zanthoxylum ; Zingiberaceae

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Tytuł:: Identification and characterization of the steroid 15α-hydroxylase gene from Penicillium raistrickii.
Autorzy:: Jia L; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
Dong J; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
Wang R; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
Mao S; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
Lu F; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China. .
Singh S; Department of Biotechnology & Food Technology, Faculty of Applied Sciences, Durban University of Technology, P.O. Box 1334, Durban, 4001, South Africa.
Wang Z; College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin, 300457, China.
Liu X; College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin, 300457, China. liu_.; Pokaż więcej
Źródło:: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2017 Aug; Vol. 101 (16), pp. 6409-6418. Date of Electronic Publication: 2017 Jun 29.
Typ publikacji:: Journal Article
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*genetics
Penicillium/*enzymology
Penicillium/*genetics
Steroid Hydroxylases/*genetics
Aryl Hydrocarbon Hydroxylases/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Gene Deletion ; Gene Expression Profiling ; Genes, Fungal ; Hydroxylation ; Norpregnenes/metabolism ; Open Reading Frames ; Penicillium/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Steroid Hydroxylases/metabolism

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Tytuł:: Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.
Autorzy:: Kumar R; Biological Sciences, Clemson University, Clemson, SC, United States of America.
Mota LC; Environmental Toxicology, Clemson University, Pendleton, SC, United States of America.
Litoff EJ; Biological Sciences, Clemson University, Clemson, SC, United States of America.
Rooney JP; NHEERL, US-EPA, Research Triangle Park, NC, United States of America.
Boswell WT; Biological Sciences, Clemson University, Clemson, SC, United States of America.
Courter E; Biological Sciences, Clemson University, Clemson, SC, United States of America.
Henderson CM; Biological Sciences, Clemson University, Clemson, SC, United States of America.
Hernandez JP; Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America.
Corton JC; NHEERL, US-EPA, Research Triangle Park, NC, United States of America.
Moore DD; Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States of America.
Baldwin WS; Biological Sciences, Clemson University, Clemson, SC, United States of America.; Environmental Toxicology, Clemson University, Pendleton, SC, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2017 Mar 28; Vol. 12 (3), pp. e0174355. Date of Electronic Publication: 2017 Mar 28 (Print Publication: 2017).
Typ publikacji:: Journal Article
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*genetics
Cytochrome P-450 Enzyme System/*genetics
Cytochrome P450 Family 2/*genetics
Receptors, Cytoplasmic and Nuclear/*genetics
Steroid Hydroxylases/*genetics
Animals ; Aryl Hydrocarbon Hydroxylases/metabolism ; CRISPR-Cas Systems ; Constitutive Androstane Receptor ; Cytochrome P-450 CYP3A ; Cytochrome P-450 Enzyme System/metabolism ; Cytochrome P450 Family 2/metabolism ; Female ; Gene Deletion ; Gene Expression ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pharmacological and Toxicological Phenomena ; Receptors, Cytoplasmic and Nuclear/metabolism ; Steroid Hydroxylases/metabolism

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Tytuł:: Overexpression of cytochrome p450 125 in Mycobacterium: a rational strategy in the promotion of phytosterol biotransformation.
Autorzy:: Su L; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Shen Y; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China. .
Xia M; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Shang Z; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Xu S; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
An X; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China.
Wang M; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin Key Laboratory of Industrial Microbiology, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2018 Oct; Vol. 45 (10), pp. 857-867. Date of Electronic Publication: 2018 Aug 02.
Typ publikacji:: Journal Article
MeSH Terms:: Androstenedione/*chemistry
Aryl Hydrocarbon Hydroxylases/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Mycobacterium/*metabolism
Nontuberculous Mycobacteria/*metabolism
Phytosterols/*metabolism
Steroid Hydroxylases/*metabolism
Androstadienes/chemistry ; Androstenediols/chemistry ; Biotransformation ; Chromatography, Liquid ; Industrial Microbiology ; Metabolic Networks and Pathways ; Oxidation-Reduction ; Proteomics ; Tandem Mass Spectrometry

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Tytuł:: The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers.
Autorzy:: Ohno M; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.
Kanayama T; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.
Moore R; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.
Ray M; Knockout Core, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.
Negishi M; Pharmacogenetics Section, Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 Dec 26; Vol. 9 (12), pp. e115663. Date of Electronic Publication: 2014 Dec 26 (Print Publication: 2014).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Aryl Hydrocarbon Hydroxylases/*metabolism
Fatty Liver/*metabolism
Liver/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Steroid Hydroxylases/*metabolism
Animals ; Aryl Hydrocarbon Hydroxylases/genetics ; Cytochrome P450 Family 2 ; Epigenesis, Genetic ; Fatty Liver/genetics ; Heat-Shock Proteins ; Histones/metabolism ; Male ; Mice ; Molecular Chaperones ; Phenobarbital/pharmacology ; Protein Binding ; Protein Transport ; RNA Polymerase II/metabolism ; Receptors, Cytoplasmic and Nuclear/genetics ; Response Elements/drug effects ; Retinoid X Receptor alpha/metabolism ; Steroid Hydroxylases/genetics ; Transcriptional Activation