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Wyświetlanie 21-26 z 26
Tytuł:
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Autorzy:
Ling Xu
Pegu, Amarendra
Rao, Ercole
Doria-Rose, Nicole
Beninga, Jochen
McKee, Krisha
Lord, Dana M.
Wei, Ronnie R.
Gejing Deng
Louder, Mark
Schmidt, Stephen D.
Mankoff, Zachary
Lan Wu
Asokan, Mangaiarkarasi
Beil, Christian
Lange, Christian
Dirk Leuschner, Wulf
Kruip, Jochen
Sendak, Rebecca
Young Do Kwon
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Źródło:
Science; 10/6/2017, Vol. 357 Issue 6359, p85-90, 6p, 4 Color Photographs, 2 Graphs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Autorzy:
Xu L; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Pegu A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Rao E; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Doria-Rose N; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Beninga J; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
McKee K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Lord DM; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Wei RR; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Deng G; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Louder M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Schmidt SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Mankoff Z; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Wu L; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Asokan M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Beil C; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Lange C; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Leuschner WD; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Kruip J; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Sendak R; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Kwon YD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Wang K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Choe M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Tartaglia LJ; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Todd JP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Burton DR; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Department of Immunology and Microbiology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Connors M; National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Koup RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA.
Yang ZY; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA.
Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA. .
Nabel GJ; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA. .
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Źródło:
Science (New York, N.Y.) [Science] 2017 Oct 06; Vol. 358 (6359), pp. 85-90. Date of Electronic Publication: 2017 Sep 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
AIDS Vaccines/*immunology
Antibodies, Neutralizing/*immunology
HIV Antibodies/*immunology
HIV-1/*immunology
Simian Acquired Immunodeficiency Syndrome/*prevention & control
AIDS Vaccines/administration & dosage ; AIDS Vaccines/pharmacokinetics ; Animals ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/genetics ; CD4 Antigens/immunology ; Crystallography, X-Ray ; HIV Antibodies/administration & dosage ; HIV Antibodies/chemistry ; HIV Antibodies/genetics ; Humans ; Macaca mulatta ; Protein Engineering ; Simian Acquired Immunodeficiency Syndrome/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation and lysis of human CD4 cells latently infected with HIV-1.
Autorzy:
Pegu A; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Asokan M; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Wu L; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Wang K; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Hataye J; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Casazza JP; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Guo X; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Shi W; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Georgiev I; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Zhou T; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Chen X; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
O'Dell S; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Todd JP; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Kwong PD; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Rao SS; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Yang ZY; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Koup RA; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Mascola JR; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
Nabel GJ; Vaccine Research Center National Institute for Allergy and Infectious Diseases, National Institutes of Health, Building 40, Room 4502, MSC-3005 40 Convent Drive, Bethesda, Maryland 20892-3005, USA.
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Źródło:
Nature communications [Nat Commun] 2015 Oct 20; Vol. 6, pp. 8447. Date of Electronic Publication: 2015 Oct 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Antibodies, Neutralizing/*pharmacology
CD4-Positive T-Lymphocytes/*drug effects
CD8-Positive T-Lymphocytes/*drug effects
Gene Expression Regulation, Viral/*drug effects
HIV Infections/*immunology
HIV-1/*drug effects
Immunologic Factors/*pharmacology
Lymphocyte Activation/*drug effects
Animals ; Base Sequence ; CD3 Complex/immunology ; CD4-Positive T-Lymphocytes/virology ; CD8-Positive T-Lymphocytes/immunology ; Cell Line ; Cytokines/drug effects ; Cytokines/immunology ; HEK293 Cells ; HIV Infections/drug therapy ; HIV-1/immunology ; Humans ; Lymphocyte Activation/immunology ; Macaca mulatta ; Molecular Sequence Data ; Real-Time Polymerase Chain Reaction ; Receptors, Antigen, T-Cell ; Simian Acquired Immunodeficiency Syndrome/immunology ; env Gene Products, Human Immunodeficiency Virus/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evident stabilization of the clinical profile in HIV/AIDS as evaluated in an open label clinical trial using a polyherbal formulation.
Autorzy:
Asokan M; HIV-AIDS Laboratory, Molecular Biology & Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.
Lone IN
Mukthey AB
Siddhartha P
Mariappa G
Kotehal PK
Satish B
Wilson E
Sahayam S
Velayutham G
Perumal R
Baskaran K
Rengarajan D
Muthusamy R
Philip M
Ravindra KC
Basha JN
Mizar P
Kaur G
Mehra NK
Kundu TK
Subbakrishna DK
Satish KS
Ranga U
Pokaż więcej
Źródło:
The Indian journal of medical research [Indian J Med Res] 2013 Jun; Vol. 137 (6), pp. 1128-44.
Typ publikacji:
Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV Infections/*drug therapy
Plant Extracts/*therapeutic use
Adult ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/drug effects ; Complementary Therapies ; Female ; Humans ; India ; Male ; Middle Aged ; Patient Safety ; Pilot Projects ; Prospective Studies ; RNA, Viral/blood ; Treatment Outcome ; Viral Load/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 21-26 z 26

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