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Wyszukujesz frazę ""Astrocytes"" wg kryterium: Temat


Tytuł :
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure.
Autorzy :
Meng Y; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Ding J; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Li C; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Fan H; School of Forensic Medicine, Southern Medical University, Guangzhou, China; School of Basic Medicine and Life Science, Hainan Medical University, Haikou, China.
He Y; School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Qiu P; School of Forensic Medicine, Southern Medical University, Guangzhou, China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Oct 01; Vol. 331, pp. 188-199. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Central Nervous System Stimulants/*toxicity
Exosomes/*metabolism
Methamphetamine/*toxicity
Neurons/*drug effects
Neurotoxicity Syndromes/*metabolism
alpha-Synuclein/*metabolism
Animals ; Astrocytes/immunology ; Astrocytes/metabolism ; Cell Line, Tumor ; Coculture Techniques ; Cytokines/metabolism ; Hippocampus/cytology ; Humans ; Injections, Intraperitoneal ; Male ; Mice, Inbred C57BL ; Neurons/immunology ; Neurons/metabolism ; Neurotoxicity Syndromes/immunology ; Nuclear Receptor Subfamily 4, Group A, Member 2/genetics ; Primary Cell Culture ; Synucleinopathies/immunology ; Synucleinopathies/metabolism
Czasopismo naukowe
Tytuł :
Effects of methylmercury on the pattern of NADPH diaphorase expression and astrocytic activation in the rat.
Autorzy :
Freire MAM; Graduate Program in Health and Society, Faculty of Health Sciences, University of State of Rio Grande do Norte (UERN), Mossoró, RN, Brazil.
Lima RR; Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, PA, Brazil.
Nascimento PC; Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, PA, Brazil.
Gomes-Leal W; Laboratory of Experimental Neuroprotection and Neuroregeneration, Institute of Biological Sciences, Federal University of Pará (UFPA), Belém, PA, Brazil.
Pereira A Jr; Department of Electrical and Biomedical Engineering, Institute of Technology, Federal University of Pará (UFPA), Belém, PA, Brazil. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Sep 15; Vol. 201, pp. 110799. Date of Electronic Publication: 2020 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Environmental Pollutants/*toxicity
Methylmercury Compounds/*toxicity
NADPH Dehydrogenase/*metabolism
Neurons/*drug effects
Visual Cortex/*drug effects
Animals ; Astrocytes/enzymology ; Behavior, Animal/drug effects ; Environmental Pollutants/metabolism ; Gold ; Humans ; Male ; Methylmercury Compounds/metabolism ; Mining ; Neurons/enzymology ; Rats ; Rats, Wistar ; Visual Cortex/enzymology ; Visual Cortex/pathology
Czasopismo naukowe
Tytuł :
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle.
Autorzy :
Theparambil SM; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Hosford PS; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Ruminot I; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Kopach O; Institute of Neurology, University College London, London, UK.
Reynolds JR; Institute of Neurology, University College London, London, UK.
Sandoval PY; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Rusakov DA; Institute of Neurology, University College London, London, UK.
Barros LF; Centro de Estudios Científicos (CECs), Valdivia, Chile.
Gourine AV; Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, London, UK. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 08; Vol. 11 (1), pp. 5073. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Bicarbonates/*metabolism
Brain/*metabolism
Extracellular Space/*metabolism
Acetazolamide/pharmacology ; Adenosine Triphosphate/metabolism ; Animals ; Astrocytes/drug effects ; Carbonic Anhydrases/metabolism ; Cells, Cultured ; Electric Stimulation ; Fluorescence ; Hippocampus/metabolism ; Hydrogen-Ion Concentration ; Mice, Inbred C57BL ; Models, Biological ; Neurons/drug effects ; Neurons/metabolism ; Purinergic Antagonists/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Receptors, Purinergic/metabolism ; Signal Transduction ; Sodium-Bicarbonate Symporters/metabolism
Czasopismo naukowe
Tytuł :
Presynaptically silent synapses are modulated by the density of surrounding astrocytes.
Autorzy :
Oyabu K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Takeda K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Kawano H; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Kubota K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Watanabe T; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
Harata NC; Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Katsurabayashi S; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan. Electronic address: .
Iwasaki K; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan; A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka, 814-0180, Japan.
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Źródło :
Journal of pharmacological sciences [J Pharmacol Sci] 2020 Oct; Vol. 144 (2), pp. 76-82. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Synaptic Transmission*
Astrocytes/*physiology
Brain/*cytology
Neurons/*physiology
Synapses/*physiology
Animals ; Astrocytes/pathology ; Cells, Cultured ; Excitatory Postsynaptic Potentials ; Female ; Mice, Inbred ICR ; Neurons/pathology ; Phylogeny ; Pregnancy
Czasopismo naukowe
Tytuł :
Effect of NMO-IgG on the interleukin-6 cascade in astrocytes via activation of the JAK/STAT3 signaling pathway.
Autorzy :
Du L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Chang H; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Xu W; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wei Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Wang Y; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China.
Yin L; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
Zhang X; Department of Neurology, Beijing Tiantan Hospital; China National Clinical Research Center for Neurological Diseases; Advanced Innovation Center for Human Brain Protection, Beijing Institute of Brain Disorders, Capital Medical University, No.119 South 4th Ring West Road, Fengtai District, Beijing 100070, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118217. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*metabolism
Immunoglobulin G/*blood
Interleukin-6/*metabolism
Janus Kinases/*metabolism
Neuromyelitis Optica/*blood
STAT3 Transcription Factor/*metabolism
Adult ; Aged ; Animals ; Astrocytes/drug effects ; Autoantibodies/blood ; Autoantibodies/pharmacology ; Cells, Cultured ; Female ; Humans ; Immunoglobulin G/pharmacology ; Interleukin-6/agonists ; Male ; Middle Aged ; Rats ; Rats, Wistar ; STAT3 Transcription Factor/agonists ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Young Adult
Czasopismo naukowe
Tytuł :
[A role for astrocytes in intellectual disabilities?]
Autorzy :
Cresto N; Interactions neurogliales dans la physiologie et pathologies cérébrales, Centre interdisciplinaire de recherche en biologie, Collège de France, CNRS UMR 7241, Inserm U1050, Labex Memolife, Université PSL, 75005 Paris, France. - Institut de psychiatrie et de neurosciences de Paris, Inserm U1266, université de Paris, 75014 Paris, France.
Billuart P; Institut de psychiatrie et de neurosciences de Paris, Inserm U1266, université de Paris, 75014 Paris, France.
Rouach N; Interactions neurogliales dans la physiologie et pathologies cérébrales, Centre interdisciplinaire de recherche en biologie, Collège de France, CNRS UMR 7241, Inserm U1050, Labex Memolife, Université PSL, 75005 Paris, France.
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Transliterated Title :
Un rôle pour les astrocytes dans les déficiences intellectuelles ?
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2020 Oct; Vol. 36 (10), pp. 847-851. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Wiadomości
MeSH Terms :
Astrocytes/*physiology
Intellectual Disability/*etiology
Intellectual Disability/*pathology
Astrocytes/pathology ; Humans ; Intellectual Disability/psychology ; Synapses/pathology ; Synapses/physiology ; Synaptic Transmission/physiology
Periodyk
Tytuł :
Localization and Expression of Sirtuins 1, 2, 6 and Plasticity-Related Proteins in the Recovery Period after a Photothrombotic Stroke in Mice.
Autorzy :
Demyanenko S; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, pr. Stachki 194/1, Rostov-on-Don 344090, Russia. Electronic address: .
Gantsgorn E; Department of Pharmacology and Clinical Pharmacology, Rostov State Medical University, st. Nakhichevansky 29, Rostov-on-Don 344022, Russia.
Rodkin S; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, pr. Stachki 194/1, Rostov-on-Don 344090, Russia.
Sharifulina S; Neuroscience Center, HiLife, University of Helsinki, Haartmaninkatu 8, P.O. Box 63, FI-00014 Helsinki, Finland.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105152. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Neuronal Plasticity*
Astrocytes/*enzymology
Cerebral Cortex/*enzymology
Intracranial Thrombosis/*complications
Neurons/*enzymology
Sirtuin 1/*metabolism
Sirtuin 2/*metabolism
Sirtuins/*metabolism
Stroke/*enzymology
Animals ; Apoptosis ; Astrocytes/pathology ; Cerebral Cortex/pathology ; Cerebral Cortex/physiopathology ; Disease Models, Animal ; Male ; Mice ; Neurons/pathology ; Recovery of Function ; Signal Transduction ; Stroke/etiology ; Stroke/pathology ; Stroke/physiopathology ; Time Factors
Czasopismo naukowe
Tytuł :
Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis.
Autorzy :
Muri L; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Oberhänsli S; Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Buri M; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Le ND; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland.
Grandgirard D; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
Bruggmann R; Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Müri RM; Department of Neurology, University of Bern, Bern, Switzerland.
Leib SL; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
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Źródło :
PloS one [PLoS One] 2020 Sep 11; Vol. 15 (9), pp. e0232863. Date of Electronic Publication: 2020 Sep 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neurogenesis*
Astrocytes/*cytology
Cerebellar Cortex/*cytology
Hippocampus/*cytology
Meningitis, Pneumococcal/*therapy
Microglia/*cytology
Transcranial Magnetic Stimulation/*adverse effects
Animals ; Astrocytes/pathology ; Cerebellar Cortex/pathology ; Cytokines/metabolism ; Hippocampus/pathology ; Male ; Microglia/pathology ; Rats ; Rats, Wistar ; Stem Cell Niche
Czasopismo naukowe
Tytuł :
Location, Location, Location: Transcriptional Control of Astrocyte Heterogeneity.
Autorzy :
Rosenberg MF; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, 94158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, 94158, USA.
Molofsky AV; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, 94158, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, 94158, USA. Electronic address: .
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Źródło :
Trends in immunology [Trends Immunol] 2020 Sep; Vol. 41 (9), pp. 753-755. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Astrocytes*
Humans
Czasopismo naukowe
Tytuł :
Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix.
Autorzy :
Cheng Y; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.; Cancer biology program, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA.
Franco-Barraza J; Cancer biology program, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA.
Wang Y; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zheng C; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Zhang L; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Qu Y; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Long Y; College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Cukierman E; Cancer biology program, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA. .
Yang ZJ; Cancer biology program, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA. .
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Źródło :
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2020 Sep; Vol. 100 (9), pp. 1208-1222. Date of Electronic Publication: 2020 May 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Astrocytes/*metabolism
Cerebellar Neoplasms/*genetics
Extracellular Matrix/*metabolism
Hedgehog Proteins/*genetics
Medulloblastoma/*genetics
Signal Transduction/*genetics
Animals ; Astrocytes/pathology ; Cell Line, Tumor ; Cerebellar Neoplasms/metabolism ; Gene Expression Regulation, Neoplastic ; Hedgehog Proteins/metabolism ; Humans ; Medulloblastoma/metabolism ; Medulloblastoma/pathology ; Mice, Knockout ; Mice, SCID ; Mice, Transgenic ; Patched-2 Receptor/genetics ; Patched-2 Receptor/metabolism ; Tumor Microenvironment/genetics ; Zinc Finger Protein GLI1/genetics ; Zinc Finger Protein GLI1/metabolism
Czasopismo naukowe
Tytuł :
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes.
Autorzy :
Barbar L; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Jain T; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Zimmer M; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Kruglikov I; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Sadick JS; Neuroscience Institute, NYU Langone School of Medicine, New York, NY 10016, USA.
Wang M; Department of Genetics & Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Kalpana K; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Rose IVL; Neuroscience Institute, NYU Langone School of Medicine, New York, NY 10016, USA.
Burstein SR; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Rusielewicz T; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Nijsure M; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Guttenplan KA; Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
di Domenico A; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Croft G; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA.
Zhang B; Department of Genetics & Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Nobuta H; Rose F. Kennedy Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Hébert JM; Rose F. Kennedy Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Liddelow SA; Neuroscience Institute, NYU Langone School of Medicine, New York, NY 10016, USA; Department of Neuroscience and Physiology, NYU Langone School of Medicine, New York, NY 10016, USA; Department of Ophthalmology, NYU Langone School of Medicine, New York, NY 10017, USA.
Fossati V; The New York Stem Cell Foundation Research Institute, New York, NY 10019, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Aug 05; Vol. 107 (3), pp. 436-453.e12. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Astrocytes/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Integrin alpha6/*metabolism
Alzheimer Disease/metabolism ; Animals ; Astrocytes/physiology ; Biomarkers/metabolism ; Flow Cytometry ; Gene Expression Profiling ; Glutamic Acid/metabolism ; Humans ; Inflammation/metabolism ; Inflammation/physiopathology ; Mice ; Patch-Clamp Techniques ; Phagocytosis/physiology ; RNA-Seq ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Astrocyte responses to experimental glaucoma in mouse optic nerve head.
Autorzy :
Quillen S; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Schaub J; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Quigley H; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Pease M; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Korneva A; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
Kimball E; Glaucoma Center of Excellence, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Maryland, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Aug 21; Vol. 15 (8), pp. e0238104. Date of Electronic Publication: 2020 Aug 21 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*physiology
Glaucoma/*pathology
Optic Nerve/*physiology
Animals ; Apoptosis ; Astrocytes/cytology ; Astrocytes/pathology ; Cell Proliferation ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Intraocular Pressure ; Mice ; Mice, Inbred C57BL ; Microscopy, Confocal ; Microscopy, Electron, Transmission ; Optic Nerve/cytology ; Optic Nerve/pathology
Czasopismo naukowe
Tytuł :
Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress.
Autorzy :
Cooper ML; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
Pasini S; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
Lambert WS; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
D'Alessandro KB; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
Yao V; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
Risner ML; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654.
Calkins DJ; Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville TN 37232-0654 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 04; Vol. 117 (31), pp. 18810-18821. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes*/metabolism
Astrocytes*/physiology
Glaucoma/*metabolism
Neurodegenerative Diseases/*metabolism
Animals ; Connexin 43/genetics ; Connexin 43/metabolism ; Female ; Gap Junctions/metabolism ; Intraocular Pressure/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Glucose metabolism links astroglial mitochondria to cannabinoid effects.
Autorzy :
Jimenez-Blasco D; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain.
Busquets-Garcia A; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.; Integrative Pharmacology and Systems Neuroscience, IMIM Hospital del Mar Medical Research Institute, Barcelona, Spain.
Hebert-Chatelain E; Canada Research Chair in Mitochondrial Signaling and Physiopathology, Université de Moncton, Moncton, New Brunswick, Canada.; Department of Biology, Université de Moncton, Moncton, New Brunswick, Canada.
Serrat R; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Vicente-Gutierrez C; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain.
Ioannidou C; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Gómez-Sotres P; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Lopez-Fabuel I; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain.
Resch-Beusher M; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain.; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain.
Resel E; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
Arnouil D; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Saraswat D; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Varilh M; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Cannich A; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Julio-Kalajzic F; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Bonilla-Del Río I; Department of Neurosciences, University of the Basque Country (UPV/EHU), Leioa, Spain.; Achucarro Basque Center for Neuroscience, Science Park of the UPV/EHU, Leioa, Spain.
Almeida A; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain.; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain.
Puente N; Department of Neurosciences, University of the Basque Country (UPV/EHU), Leioa, Spain.; Achucarro Basque Center for Neuroscience, Science Park of the UPV/EHU, Leioa, Spain.
Achicallende S; Department of Neurosciences, University of the Basque Country (UPV/EHU), Leioa, Spain.; Achucarro Basque Center for Neuroscience, Science Park of the UPV/EHU, Leioa, Spain.
Lopez-Rodriguez ML; Department of Organic Chemistry, Complutense University, Madrid, Spain.
Jollé C; Department of Physiology, University of Lausanne, Lausanne, Switzerland.
Déglon N; Department of Clinical Neurosciences, Laboratory of Cellular and Molecular Neurotherapies (LCMN), University of Lausanne, Lausanne, Switzerland.
Pellerin L; Department of Physiology, University of Lausanne, Lausanne, Switzerland.; Centre de Résonance Magnétique des Systèmes Biologiques UMR 5536, CNRS-University of Bordeaux, Bordeaux, France.; INSERM U1082, University of Poitiers, Poitiers, France.
Josephine C; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Bonvento G; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Panatier A; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Lutz B; Institute of Physiological Chemistry, University Medical Center, Mainz, Germany.; Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Piazza PV; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.; Aelis Farma, Bordeaux, France.
Guzmán M; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Instituto Universitario de Investigación Neuroquímica (IUIN) and Department of Biochemistry and Molecular Biology, Complutense University, Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
Bellocchio L; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Bouzier-Sore AK; Centre de Résonance Magnétique des Systèmes Biologiques UMR 5536, CNRS-University of Bordeaux, Bordeaux, France.
Grandes P; Department of Neurosciences, University of the Basque Country (UPV/EHU), Leioa, Spain.; Achucarro Basque Center for Neuroscience, Science Park of the UPV/EHU, Leioa, Spain.; Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.
Bolaños JP; Institute of Functional Biology and Genomics, University of Salamanca, CSIC, Salamanca, Spain. .; Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. .; Institute of Biomedical Research of Salamanca, University Hospital of Salamanca, University of Salamanca, CSIC, Salamanca, Spain. .
Marsicano G; INSERM, U1215 NeuroCentre Magendie, Bordeaux, France. .; University of Bordeaux, Bordeaux, France. .
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Źródło :
Nature [Nature] 2020 Jul; Vol. 583 (7817), pp. 603-608. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Energy Metabolism*/drug effects
Astrocytes/*metabolism
Glucose/*metabolism
Mitochondria/*metabolism
Receptor, Cannabinoid, CB1/*metabolism
Animals ; Astrocytes/cytology ; Astrocytes/drug effects ; Cannabinoid Receptor Agonists/pharmacology ; Cells, Cultured ; Dronabinol/pharmacology ; Electron Transport Complex I/chemistry ; Electron Transport Complex I/metabolism ; Glycolysis/drug effects ; Humans ; Hypoxia-Inducible Factor 1/metabolism ; Lactic Acid/metabolism ; Male ; Mice ; Mitochondria/drug effects ; Mitochondrial Membranes/metabolism ; Oxidation-Reduction ; Phosphorylation ; Reactive Oxygen Species/metabolism ; Receptor, Cannabinoid, CB1/agonists ; Social Behavior
Czasopismo naukowe
Tytuł :
Ginsenoside Rg1-induced activation of astrocytes promotes functional recovery via the PI3K/Akt signaling pathway following spinal cord injury.
Autorzy :
Xu L; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Tang YY; Department of Orthopedics, Yixing Second People's Hospital, Yixing 214221, China.
Ben XL; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Cheng MH; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Guo WX; Department of Orthopedics, Suzhou Kowloon Hospital, Suzhou 215021, China.
Liu Y; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China.
Lu ZF; Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China. Electronic address: .
Deng JL; Department of Orthopaedics, Suqian First Hospital, Suqian, Jiangsu 223800, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Jul 01; Vol. 252, pp. 117642. Date of Electronic Publication: 2020 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*drug effects
Ginsenosides/*pharmacology
Spinal Cord Injuries/*drug therapy
Wound Healing/*drug effects
Animals ; Astrocytes/metabolism ; Female ; Male ; Nerve Growth Factors/metabolism ; Phosphatidylinositol 3-Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Signal Transduction/drug effects ; Spinal Cord Injuries/physiopathology
Czasopismo naukowe
Tytuł :
HIV infects astrocytes in vivo and egresses from the brain to the periphery.
Autorzy :
Lutgen V; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
Narasipura SD; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
Barbian HJ; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
Richards M; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
Wallace J; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
Razmpour R; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America.
Buzhdygan T; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America.
Ramirez SH; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United States of America.
Prevedel L; Department of Neuroscience, Cell Biology and Anatomy, The University of Texas Medical Branch, Galveston, Texas, United States of America.
Eugenin EA; Department of Neuroscience, Cell Biology and Anatomy, The University of Texas Medical Branch, Galveston, Texas, United States of America.
Al-Harthi L; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, Illinois, United States of America.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 11; Vol. 16 (6), pp. e1008381. Date of Electronic Publication: 2020 Jun 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes*/metabolism
Astrocytes*/pathology
Astrocytes*/virology
Blood-Brain Barrier*/metabolism
Blood-Brain Barrier*/pathology
Blood-Brain Barrier*/virology
HIV Infections*/genetics
HIV Infections*/metabolism
HIV Infections*/pathology
Hippocampus*/metabolism
Hippocampus*/pathology
Hippocampus*/virology
Virus Release*
HIV-1/*metabolism
Animals ; Anti-Retroviral Agents/pharmacology ; Cell Line, Tumor ; HIV-1/genetics ; Humans ; Mice ; Mice, Inbred NOD ; Mice, Knockout ; Mice, SCID
Czasopismo naukowe
Tytuł :
Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease.
Autorzy :
Guillemaud O; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Ceyzériat K; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Saint-Georges T; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Cambon K; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Petit F; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Ben Haim L; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Carrillo-de Sauvage MA; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Guillermier M; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Bernier S; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Hérard AS; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Joséphine C; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Bémelmans AP; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Brouillet E; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Hantraye P; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Bonvento G; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Escartin C; Université Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France. Electronic address: .
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Źródło :
Neurobiology of aging [Neurobiol Aging] 2020 Jun; Vol. 90, pp. 135-146. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*genetics
Alzheimer Disease/*metabolism
Astrocytes/*metabolism
Alzheimer Disease/pathology ; Amyloidogenic Proteins/metabolism ; Animals ; Astrocytes/pathology ; Disease Models, Animal ; Hippocampus/cytology ; Hippocampus/metabolism ; Hippocampus/pathology ; Janus Kinase 2/metabolism ; Mice, Transgenic ; Phosphorylation ; STAT3 Transcription Factor/metabolism ; Signal Transduction/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles.
Autorzy :
Moro A; Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), University Medical Center Amsterdam, Amsterdam, the Netherlands.; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit (VU) Amsterdam, Amsterdam, the Netherlands.
van Woerden GM; Department of Neuroscience, ENCORE Expertise Center for Neurodevelopmental Disorders, Erasmus MC, Rotterdam, the Netherlands.
Toonen RF; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit (VU) Amsterdam, Amsterdam, the Netherlands.
Verhage M; Department of Clinical Genetics, Center for Neurogenomics and Cognitive Research (CNCR), University Medical Center Amsterdam, Amsterdam, the Netherlands.; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit (VU) Amsterdam, Amsterdam, the Netherlands.
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Źródło :
PLoS biology [PLoS Biol] 2020 Aug 10; Vol. 18 (8), pp. e3000826. Date of Electronic Publication: 2020 Aug 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Astrocytes/*metabolism
Brain-Derived Neurotrophic Factor/*genetics
Calcium/*metabolism
Calcium-Calmodulin-Dependent Protein Kinase Type 2/*genetics
Neurons/*metabolism
Protein Subunits/*genetics
Animals ; Astrocytes/cytology ; Brain-Derived Neurotrophic Factor/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/deficiency ; Cyclic AMP Response Element-Binding Protein/genetics ; Cyclic AMP Response Element-Binding Protein/metabolism ; Feedback, Physiological ; Gene Expression Regulation ; Hippocampus/cytology ; Hippocampus/metabolism ; Mice ; Mice, Transgenic ; Neurons/cytology ; Phosphorylation ; Primary Cell Culture ; Protein Subunits/deficiency ; Synapses/physiology ; Synaptic Transmission ; Time-Lapse Imaging
Czasopismo naukowe
Tytuł :
Exocytosis of large-diameter lysosomes mediates interferon γ-induced relocation of MHC class II molecules toward the surface of astrocytes.
Autorzy :
Božić M; Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia.
Verkhratsky A; Celica Biomedical, Tehnološki park 24, 1000, Ljubljana, Slovenia.; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.; Achucarro Center for Neuroscience, IKERBASQUE, 48011, Bilbao, Spain.
Zorec R; Celica Biomedical, Tehnološki park 24, 1000, Ljubljana, Slovenia. .; Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia. .
Stenovec M; Celica Biomedical, Tehnološki park 24, 1000, Ljubljana, Slovenia. .; Laboratory of Neuroendocrinology-Molecular Cell Physiology, Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000, Ljubljana, Slovenia. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Aug; Vol. 77 (16), pp. 3245-3264. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*metabolism
Cell Membrane/*metabolism
Exocytosis/*physiology
Histocompatibility Antigens Class II/*metabolism
Interferon-gamma/*metabolism
Lysosomes/*metabolism
Lysosomes/*physiology
Animals ; Antigen Presentation/physiology ; Astrocytes/physiology ; Biomarkers/metabolism ; Cell Membrane/physiology ; Cells, Cultured ; Central Nervous System/metabolism ; Central Nervous System/physiology ; Endocytosis/physiology ; Endosomes/metabolism ; Endosomes/physiology ; Female ; Inflammation/metabolism ; Inflammation/pathology ; Protein Transport/physiology ; Rats ; Rats, Wistar ; Secretory Vesicles/metabolism ; Secretory Vesicles/physiology
Czasopismo naukowe
Tytuł :
Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes.
Autorzy :
Sharma KD; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Schaal D; Department of Biology, Ouachita Baptist University, Arkadelphia, Arkansas, United States of America.
Kore RA; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Hamzah RN; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Pandanaboina SC; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Hayar A; Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Griffin RJ; Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Srivatsan M; Department of Biological Sciences and Arkansas Biosciences Institute, Arkansas State University, Jonesboro, Arkansas, United States of America.
Reyna NS; Department of Biology, Ouachita Baptist University, Arkadelphia, Arkansas, United States of America.
Xie JY; Department of Basic Sciences, New York Institute of Technology College of Osteopathic Medicine at Arkansas State University, Jonesboro, Arkansas, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Jul 10; Vol. 15 (7), pp. e0234614. Date of Electronic Publication: 2020 Jul 10 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Astrocytes/*metabolism
Cell Differentiation/*physiology
Exosomes/*physiology
Neural Stem Cells/*metabolism
Animals ; Astrocytes/physiology ; Cell Proliferation ; Cells, Cultured ; Coculture Techniques ; Elastin/metabolism ; Exosomes/metabolism ; Gene Expression Regulation/genetics ; Glioma/metabolism ; Humans ; Interleukin-6/metabolism ; Nerve Tissue Proteins/metabolism ; Neural Stem Cells/physiology ; Neurons/metabolism ; Primary Cell Culture ; Rats ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe

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