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Wyświetlanie 1-8 z 8
Tytuł :
Design, Synthesis, and Biological Evaluation of Novel Triazolothiadiazoles Derived From NSAIDs as Anticancer Agents.
Autorzy :
Aytaç P; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.
Sahin ID; School of Medicine, Koç University, Istanbul, Turkey.
Atalay; CanSyL, Bioinformatics Department, Graduate School of Informatics, ODTU, 06800, Ankara, Turkey.
Tozkoparan B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2021 Jun 22. Date of Electronic Publication: 2021 Jun 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines.
Autorzy :
Avci ME; Department of Molecular Biology and Genetics, Bilkent University, 06800, Ankara, Turkey. .; Izmir International Biomedicine and Genome Institute (iBG-izmir), Dokuz Eylul University, 35340, Izmir, Turkey. .
Keskus AG; Interdisciplinary Program in Neuroscience, Bilkent University, 06800, Ankara, Turkey.
Targen S; Department of Molecular Biology and Genetics, Bilkent University, 06800, Ankara, Turkey.
Isilak ME; Department of Molecular Biology and Genetics, Bilkent University, 06800, Ankara, Turkey.; UNAM-Institute of Materials Science and Nanotechnology, Bilkent University, 06800, Ankara, Turkey.
Ozturk M; Department of Molecular Biology and Genetics, Bilkent University, 06800, Ankara, Turkey.; Izmir International Biomedicine and Genome Institute (iBG-izmir), Dokuz Eylul University, 35340, Izmir, Turkey.
Atalay RC; Medical Informatics Department, Graduate School of Informatics, Middle East Technical University, 06800, Ankara, Turkey.
Adams MM; Department of Psychology, Bilkent University, 06800, Ankara, Turkey.; Interdisciplinary Program in Neuroscience, Bilkent University, 06800, Ankara, Turkey.; UNAM-Institute of Materials Science and Nanotechnology, Bilkent University, 06800, Ankara, Turkey.
Konu O; Department of Molecular Biology and Genetics, Bilkent University, 06800, Ankara, Turkey. .; Interdisciplinary Program in Neuroscience, Bilkent University, 06800, Ankara, Turkey. .; UNAM-Institute of Materials Science and Nanotechnology, Bilkent University, 06800, Ankara, Turkey. .
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Źródło :
Scientific reports [Sci Rep] 2018 Jan 25; Vol. 8 (1), pp. 1570. Date of Electronic Publication: 2018 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Line, Tumor*
Disease Models, Animal*
Heterografts*
Zebrafish*
Acetylcholinesterase/*deficiency
Liver Neoplasms/*pathology
Animals ; Neoplasm Transplantation
Czasopismo naukowe
Tytuł :
Synthesis of Novel Benzothiazole-Piperazine Derivatives and Their Biological Evaluation as Acetylcholinesterase Inhibitors and Cytotoxic Agents.
Autorzy :
Gurdal EE; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, 34755, Kayisdagi, Istanbul. Turkey.
Turgutalp B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, 34755, Kayisdagi, Istanbul. Turkey.
Gulcan HO; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Eastern Mediterranean University, Famagusta. Cyprus.
Ercetin T; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Eastern Mediterranean University, Famagusta. Cyprus.
Sahin MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Eastern Mediterranean University, Famagusta. Cyprus.
Durmaz I; Bioinformatics Department, Graduate School of Informatics, Middle East Technical University, Ankara. Turkey.
Atalay RC; Bioinformatics Department, Graduate School of Informatics, Middle East Technical University, Ankara. Turkey.
Nguyen QD; Martin-Luther- Universität Halle-Wittenberg, Institute of Pharmacy, Medicinal Chemistry Department, Halle (Saale). Germany.
Sippl W; Martin-Luther- Universität Halle-Wittenberg, Institute of Pharmacy, Medicinal Chemistry Department, Halle (Saale). Germany.
Yarim M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, 34755, Kayisdagi, Istanbul. Turkey.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2017; Vol. 17 (13), pp. 1837-1845.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholinesterase/*drug effects
Benzothiazoles/*chemistry
Cholinesterase Inhibitors/*chemical synthesis
Cholinesterase Inhibitors/*pharmacology
Piperazine/*chemistry
Cell Line, Tumor ; Cholinesterase Inhibitors/chemistry ; Donepezil/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Spectrum Analysis/methods ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis of novel substituted purine derivatives and identification of the cell death mechanism.
Autorzy :
Demir Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey.
Guven EB; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey.
Ozbey S; Department of Engineering Physics, Faculty of Engineering, Hacettepe University, 06800 Beytepe, Ankara, Turkey.
Kazak C; Department of Physics, Faculty of Arts and Sciences, Ondokuz Mayıs University, 55139 Kurupelit, Samsun, Turkey.
Atalay RC; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey. Electronic address: .
Tuncbilek M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2015 Jan 07; Vol. 89, pp. 701-20. Date of Electronic Publication: 2014 Oct 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Purines/*chemistry
Purines/*pharmacology
Antineoplastic Agents/chemistry ; Cell Death/drug effects ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; HCT116 Cells ; Hep G2 Cells ; Humans ; Models, Molecular ; Molecular Structure ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Bi-k-bi clustering: mining large scale gene expression data using two-level biclustering.
Autorzy :
Carkacioğlu L; Department of Computer Engineering, Middle East Technical University, Ankara, Turkey. />Atalay RC
Konu O
Atalay V
Can T
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Źródło :
International journal of data mining and bioinformatics [Int J Data Min Bioinform] 2010; Vol. 4 (6), pp. 701-21.
Typ publikacji :
Journal Article
MeSH Terms :
Databases, Genetic*
Gene Expression*
Gene Expression Profiling*
Data Mining/*methods
Cluster Analysis ; Humans ; Oligonucleotide Array Sequence Analysis
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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