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Wyszukujesz frazę ""Autocrine Communication"" wg kryterium: Temat


Tytuł :
Endothelial Autocrine Signaling through CXCL12/CXCR4/FoxM1 Axis Contributes to Severe Pulmonary Arterial Hypertension.
Autorzy :
Yi D; Department of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Liu B; Department of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Wang T; Department of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
Liao Q; Department of Preventative Medicine, Zhejiang Provincial Key Laboratory of Pathophysiology Technology, Medical School of Ningbo University, Ningbo 315211, China.
Zhu MM; Program for Lung and Vascular Biology, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Division of Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Zhao YY; Program for Lung and Vascular Biology, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.; Department of Pediatrics, Division of Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Dai Z; Department of Internal Medicine, College of Medicine-Phoenix, University of Arizona, Phoenix, AZ 85004, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 20; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 20.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*
Signal Transduction*
Chemokine CXCL12/*metabolism
Endothelial Cells/*metabolism
Forkhead Box Protein M1/*metabolism
Pulmonary Arterial Hypertension/*etiology
Pulmonary Arterial Hypertension/*metabolism
Receptors, CXCR4/*metabolism
Animals ; Biomarkers ; Cells, Cultured ; Disease Models, Animal ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Fluorescent Antibody Technique ; Humans ; Hypoxia/metabolism ; Immunohistochemistry ; Mice ; Mice, Transgenic ; Pulmonary Arterial Hypertension/diagnosis ; Severity of Illness Index ; Vascular Remodeling
Czasopismo naukowe
Tytuł :
Autocrine secretion of insulin-like growth factor-I mediates growth hormone-stimulated DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Autorzy :
Kurihara K; Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado City, Saitama, 350-0295, Japan.
Moteki H; Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado City, Saitama, 350-0295, Japan.
Kimura M; Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado City, Saitama, 350-0295, Japan.
Ogihara M; Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado City, Saitama, 350-0295, Japan. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jan 15; Vol. 891, pp. 173753. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*
Cell Proliferation/*drug effects
DNA Replication/*drug effects
Hepatocytes/*drug effects
Human Growth Hormone/*pharmacology
Insulin-Like Growth Factor I/*metabolism
Animals ; Cells, Cultured ; Hepatocytes/metabolism ; Janus Kinase 2/metabolism ; Male ; Phosphorylation ; Primary Cell Culture ; Rats, Wistar ; Receptor, IGF Type 1/metabolism ; Receptors, Somatotropin/agonists ; Receptors, Somatotropin/metabolism ; Secretory Pathway ; Signal Transduction ; Type C Phospholipases/metabolism
Czasopismo naukowe
Tytuł :
Paracrine and autocrine control of insulin secretion in human islets: evidence and pending questions.
Autorzy :
Henquin JC; Unit of Endocrinology and Metabolism, Faculty of Medicine, University of Louvain, Brussels, Belgium.
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Źródło :
American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2021 Jan 01; Vol. 320 (1), pp. E78-E86. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Autocrine Communication/*physiology
Insulin Secretion/*physiology
Islets of Langerhans/*metabolism
Paracrine Communication/*physiology
Autocrine Communication/drug effects ; Hormones/pharmacology ; Humans ; Insulin Secretion/drug effects ; Islets of Langerhans/drug effects ; Paracrine Communication/drug effects
Czasopismo naukowe
Tytuł :
Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma.
Autorzy :
Sreenivasan L; Department of Medicine, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada.
Wang H; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.; Department of Microbiology and Immunology, Jinan University, Guangzhou, People's Republic of China.
Yap SQ; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Leclair P; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Tam A; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Lim CJ; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada. .; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada. .
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Źródło :
Cell death & disease [Cell Death Dis] 2020 Dec 05; Vol. 11 (12), pp. 1035. Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication*/drug effects
Autocrine Communication*/genetics
Drug Resistance, Neoplasm*/genetics
Signal Transduction*/drug effects
Brain Neoplasms/*drug therapy
Brain Neoplasms/*metabolism
Interleukin-6/*metabolism
Medulloblastoma/*drug therapy
Medulloblastoma/*metabolism
STAT3 Transcription Factor/*metabolism
Cell Line, Tumor ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Medulloblastoma/genetics ; Medulloblastoma/pathology ; Niclosamide/pharmacology ; Niclosamide/therapeutic use ; Receptors, Interleukin-6/metabolism ; Vincristine/pharmacology ; Vincristine/therapeutic use
Czasopismo naukowe
Tytuł :
Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair.
Autorzy :
Nakamura M; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Verboon JM; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Allen TE; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Abreu-Blanco MT; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Liu R; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Dominguez ANM; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Delrow JJ; Genomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
Parkhurst SM; Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Dec 11; Vol. 16 (12), pp. e1009186. Date of Electronic Publication: 2020 Dec 11 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Autocrine Communication*
Signal Transduction*
Wound Healing*
Actins/*metabolism
Insulin/*metabolism
Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Profilins/genetics ; Profilins/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Role of GnRH and GnIH in paracrine/autocrine control of final oocyte maturation.
Autorzy :
Fallah HP; Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada.
Habibi HR; Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada. Electronic address: .
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Źródło :
General and comparative endocrinology [Gen Comp Endocrinol] 2020 Dec 01; Vol. 299, pp. 113619. Date of Electronic Publication: 2020 Sep 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication*
Meiosis*
Paracrine Communication*
Gonadotropin-Releasing Hormone/*pharmacology
Hypothalamic Hormones/*pharmacology
Oocytes/*cytology
Ovarian Follicle/*cytology
Animals ; Female ; Oocytes/drug effects ; Oocytes/metabolism ; Ovarian Follicle/drug effects ; Ovarian Follicle/metabolism ; Zebrafish
Czasopismo naukowe
Tytuł :
An Autocrine Role for CXCL1 in Progression of Hepatocellular Carcinoma.
Autorzy :
Dahlquist KJV; Department of Chemistry, Bethel University, Saint Paul, MN, U.S.A.
Voth LC; Department of Chemistry, Bethel University, Saint Paul, MN, U.S.A.
Fee AJ; Department of Chemistry, Bethel University, Saint Paul, MN, U.S.A.
Stoeckman AK; Department of Chemistry, Bethel University, Saint Paul, MN, U.S.A. .
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Źródło :
Anticancer research [Anticancer Res] 2020 Nov; Vol. 40 (11), pp. 6075-6081.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*/drug effects
Disease Progression*
Carcinoma, Hepatocellular/*metabolism
Carcinoma, Hepatocellular/*pathology
Chemokine CXCL1/*metabolism
Liver Neoplasms/*metabolism
Liver Neoplasms/*pathology
Animals ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Glucose/pharmacology ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Humans ; Mice ; Palmitic Acid/toxicity ; Rats ; Receptors, Interleukin-8B/metabolism
Czasopismo naukowe
Tytuł :
Interleukin-34, a Novel Paracrine/Autocrine Factor in Mouse Testis, and Its Possible Role in the Development of Spermatogonial Cells In Vitro.
Autorzy :
Sawaied A; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.; The Center of Advanced Research and Education in Reproduction (CARER), Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
Lunenfeld E; The Center of Advanced Research and Education in Reproduction (CARER), Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.; Department of OB/GYN, Soroka Medical Center, Beer Sheva 8410501, Israel.
Huleihel M; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.; The Center of Advanced Research and Education in Reproduction (CARER), Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 30; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*
Cell Differentiation*
Paracrine Communication*
Interleukins/*metabolism
Spermatogonia/*cytology
Testis/*cytology
Animals ; Cells, Cultured ; In Vitro Techniques ; Male ; Mice ; Mice, Inbred ICR ; Spermatogonia/metabolism ; Testis/metabolism
Czasopismo naukowe
Tytuł :
ANGPTL8 has both endocrine and autocrine effects on substrate utilization.
Autorzy :
Oldoni F; Departments of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Cheng H; Departments of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Banfi S; Departments of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Gusarova V; Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Cohen JC; Center for Human Nutrition, and.
Hobbs HH; Departments of Molecular Genetics and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Howard Hughes Medical Institute, University of Texas Southwestern (UTSW) Medical Center, Dallas, Texas, USA.
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Źródło :
JCI insight [JCI Insight] 2020 Sep 03; Vol. 5 (17). Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Autocrine Communication*
Adipose Tissue/*metabolism
Angiopoietin-like Proteins/*physiology
Dietary Fats/*metabolism
Lipoprotein Lipase/*metabolism
Liver/*metabolism
Triglycerides/*metabolism
Adipose Tissue/cytology ; Animals ; Female ; Liver/cytology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Paracrine Communication
Czasopismo naukowe
Tytuł :
Schwann Cell Autocrine and Paracrine Regulatory Mechanisms, Mediated by Allopregnanolone and BDNF, Modulate PKCε in Peripheral Sensory Neurons.
Autorzy :
Bonalume V; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Caffino L; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Castelnovo LF; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.; Marine Science Institute, The University of Texas at Austin, 750 Channel View Drive, Port Aransas, TX 78373, USA.
Faroni A; Blond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Giavarini F; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Liu S; Institute of Pharmacology, Heidelberg University, 68167 Mannheim, Germany.
Caruso D; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Schmelz M; Experimental Pain Research, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Fumagalli F; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
Carr RW; Experimental Pain Research, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Magnaghi V; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.
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Źródło :
Cells [Cells] 2020 Aug 11; Vol. 9 (8). Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication/*physiology
Brain-Derived Neurotrophic Factor/*metabolism
Neuralgia/*metabolism
Paracrine Communication/*physiology
Pregnanolone/*metabolism
Schwann Cells/*metabolism
Animals ; Autocrine Communication/genetics ; Blotting, Western ; Cells, Cultured ; Chromatography, Liquid ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique ; Ganglia, Spinal/metabolism ; Humans ; Hyperalgesia/metabolism ; Paracrine Communication/genetics ; Rats, Sprague-Dawley ; Sensory Receptor Cells/metabolism ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Evidence that ABC transporter-mediated autocrine export of an eicosanoid signaling molecule enhances germ cell chemotaxis in the colonial tunicate Botryllus schlosseri .
Autorzy :
Kassmer SH; Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA .
Rodriguez D; Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.
De Tomaso AW; Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106, USA.
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Źródło :
Development (Cambridge, England) [Development] 2020 Aug 07; Vol. 147 (15). Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Autocrine Communication*
Chemotaxis*
Signal Transduction*
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid/*metabolism
ATP-Binding Cassette Transporters/*metabolism
Germ Cells/*metabolism
Urochordata/*metabolism
Animals ; Arachidonate 12-Lipoxygenase/metabolism ; Germ Cells/cytology ; Humans ; Receptors, G-Protein-Coupled/metabolism ; Urochordata/cytology
Czasopismo naukowe
Tytuł :
Oxidative Stress Induces a VEGF Autocrine Loop in the Retina: Relevance for Diabetic Retinopathy.
Autorzy :
Rossino MG; Department of Biology, University of Pisa, 56126 Pisa, Italy.
Lulli M; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, 50134 Florence, Italy.
Amato R; Department of Biology, University of Pisa, 56126 Pisa, Italy.
Cammalleri M; Department of Biology, University of Pisa, 56126 Pisa, Italy.; Interdepartmental Research Center Nutrafood 'Nutraceuticals and Food for Health', University of Pisa, 56124 Pisa, Italy.
Monte MD; Department of Biology, University of Pisa, 56126 Pisa, Italy.; Interdepartmental Research Center Nutrafood 'Nutraceuticals and Food for Health', University of Pisa, 56124 Pisa, Italy.
Casini G; Department of Biology, University of Pisa, 56126 Pisa, Italy.; Interdepartmental Research Center Nutrafood 'Nutraceuticals and Food for Health', University of Pisa, 56124 Pisa, Italy.
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Źródło :
Cells [Cells] 2020 Jun 11; Vol. 9 (6). Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication*/drug effects
Oxidative Stress*/drug effects
Diabetic Retinopathy/*metabolism
Diabetic Retinopathy/*pathology
Retina/*metabolism
Retina/*pathology
Vascular Endothelial Growth Factor A/*metabolism
Animals ; Cell Line ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Culture Media, Conditioned/pharmacology ; Diabetic Retinopathy/genetics ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice, Inbred C57BL ; Models, Biological ; NF-E2-Related Factor 2/metabolism ; Protein Transport/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
CGRP derived from cardiac fibroblasts is an endogenous suppressor of cardiac fibrosis.
Autorzy :
Li W; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.; Department of Pharmacy, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Changsha, Hunan 410011, China.
Zhang Z; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.
Li X; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.
Cai J; Department of Forensic Science, School of Basic Medical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410013, China.
Li D; Department of Pharmacy, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan 410078, China.
Du J; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.; Department of Pharmacy, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha, Hunan 410078, China.
Zhang B; Department of Pharmacy, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Changsha, Hunan 410011, China.
Xiang D; Department of Pharmacy, The Second Xiangya Hospital, Central South University, No. 139 Renmin Middle Road, Changsha, Hunan 410011, China.
Li N; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.
Li Y; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan 410078, China.
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Źródło :
Cardiovascular research [Cardiovasc Res] 2020 Jun 01; Vol. 116 (7), pp. 1335-1348.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*
Calcitonin Gene-Related Peptide/*metabolism
Cardiomyopathies/*metabolism
Fibroblasts/*metabolism
Myocardium/*metabolism
Animals ; Calcitonin Gene-Related Peptide/genetics ; Calcium Signaling ; Cardiomyopathies/genetics ; Cardiomyopathies/pathology ; Cardiomyopathies/prevention & control ; Cells, Cultured ; Disease Models, Animal ; Fibroblasts/pathology ; Fibrosis ; Humans ; Male ; Mice ; Myocardium/pathology ; NF-kappa B/metabolism ; Rats, Sprague-Dawley ; TRPA1 Cation Channel/metabolism
Czasopismo naukowe
Tytuł :
Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E 2 Activation in Human Podocytes.
Autorzy :
Mangelsen E; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Charitéplatz 1, 10117 Berlin, Germany.
Rothe M; Lipidomix GmbH, Robert-Rössle-Str. 10, B55, 13125 Berlin, Germany.
Schulz A; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Charitéplatz 1, 10117 Berlin, Germany.
Kourpa A; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Electrochemical Signaling in Development and Disease, Robert-Rössle-Str. 10, 13125 Berlin, Germany.
Panáková D; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Electrochemical Signaling in Development and Disease, Robert-Rössle-Str. 10, 13125 Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Potsdamer Straße 58, 10785 Berlin, Germany.
Kreutz R; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Charitéplatz 1, 10117 Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Potsdamer Straße 58, 10785 Berlin, Germany.
Bolbrinker J; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Charitéplatz 1, 10117 Berlin, Germany.
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Źródło :
Cells [Cells] 2020 May 19; Vol. 9 (5). Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication*
Signal Transduction*
Dinoprostone/*analogs & derivatives
Podocytes/*metabolism
Receptors, Prostaglandin E, EP2 Subtype/*metabolism
Receptors, Prostaglandin E, EP4 Subtype/*metabolism
Animals ; Cell Differentiation ; Cyclic AMP/metabolism ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Dinoprostone/metabolism ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Metabolome ; Podocytes/cytology ; Rats, Wistar ; Receptors, Prostaglandin E, EP2 Subtype/antagonists & inhibitors ; Receptors, Prostaglandin E, EP2 Subtype/genetics ; Receptors, Prostaglandin E, EP4 Subtype/antagonists & inhibitors ; Receptors, Prostaglandin E, EP4 Subtype/genetics ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/genetics ; Renal Insufficiency, Chronic/metabolism ; Shear Strength ; Stress, Mechanical
Czasopismo naukowe
Tytuł :
Autocrine Bradykinin Release Promotes Ischemic Preconditioning-Induced Cytoprotection in Bovine Aortic Endothelial Cells.
Autorzy :
Bellis A; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.; Dipartimento Emergenza Accettazione, Unità Operativa Complessa Cardiologia con UTIC ed Emodinamica, Azienda Ospedaliera 'Antonio Cardarelli', via A. Cardarelli n. 9, Napoli, 80131 Naples, Italy.
Sorriento D; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Fiordelisi A; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Izzo R; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Sadoshima J; Department of Cell Biology and Molecular Medicine, Rutgers-New Jersey Medical School, 185 S. Orange Ave, MSB G609, Newark, NJ 07103, USA.
Mauro C; Dipartimento Emergenza Accettazione, Unità Operativa Complessa Cardiologia con UTIC ed Emodinamica, Azienda Ospedaliera 'Antonio Cardarelli', via A. Cardarelli n. 9, Napoli, 80131 Naples, Italy.
Cerasuolo F; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Mancusi C; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Barbato E; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Pilato E; Dipartimento di Emergenze Cardiovascolari, Medicina Clinica e dell'Invecchiamento, Azienda Ospedaliera Università, FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Trimarco B; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
Morisco C; Dipartimento di Scienze Biomediche Avanzate, Università FEDERICO II, via S. Pansini n. 5, Napoli, 80131 Naples, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Apr 23; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Autocrine Communication*
Cytoprotection*
Ischemic Preconditioning*
Aorta/*cytology
Aorta/*metabolism
Bradykinin/*biosynthesis
Endothelial Cells/*metabolism
Animals ; Apoptosis ; Cattle ; Endocytosis ; Hypoxia/metabolism ; Protein Binding ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
Autorzy :
Hollenhorst MI; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
Jurastow I; Institute of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Giessen, Germany.; Department of Anesthesiology and Intensive Care Medicine (CS), University Hospital Charité, Humboldt University of Berlin, Berlin, Germany.
Nandigama R; Institute of Anatomy and Cell Biology, University of Würzburg, Würzburg, Germany.
Appenzeller S; Comprehensive Cancer Centre Mainfranken, University of Würzburg, Würzburg, Germany.
Li L; Core Unit SysMed, University of Würzburg, Würzburg, Germany.
Vogel J; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), Würzburg, Germany.
Wiederhold S; Institute of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Giessen, Germany.
Althaus M; School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Empting M; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; German Centre for Infection Research (DZIF), Saarbrücken, Germany.
Altmüller J; Cologne Centre for Genomics, University of Cologne, Cologne, Germany.
Hirsch AKH; Department of Drug Design and Optimization (DDOP), Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS)-Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.; Department of Pharmacy, Saarland University, Saarbrücken, Germany.; German Centre for Infection Research (DZIF), Saarbrücken, Germany.
Flockerzi V; Institute of Experimental and Clinical Pharmacology and Toxicology/PZMS, Saarland University, Homburg, Germany.
Canning BJ; Department of Medicine, Division of Allergy and Clinical Immunology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Saliba AE; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz-Centre for Infection Research (HZI), Würzburg, Germany.
Krasteva-Christ G; Institute of Anatomy and Cell Biology, Saarland University, Homburg, Germany.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Jan; Vol. 34 (1), pp. 316-332. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autocrine Communication*
Paracrine Communication*
Acetylcholine/*metabolism
Calcium/*metabolism
Flavoring Agents/*pharmacology
Taste/*physiology
Trachea/*metabolism
Animals ; Chemoreceptor Cells/drug effects ; Chemoreceptor Cells/metabolism ; Choline O-Acetyltransferase/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Muscarinic/physiology ; Signal Transduction ; Single-Cell Analysis ; TRPM Cation Channels/physiology ; Taste/drug effects ; Trachea/drug effects ; Transcriptome
Czasopismo naukowe
Tytuł :
Vascular calcification: New insights into endothelial cells.
Autorzy :
Yuan C; Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR China.
Ni L; Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR China.
Zhang C; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China; Cardiovascular Research Institute, Wuhan University, Wuhan 430060, PR China; Hubei Key Laboratory of Cardiology, Wuhan 430060, PR China. Electronic address: .
Hu X; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, PR China. Electronic address: .
Wu X; Department of Nephrology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR China. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2021 Mar; Vol. 134, pp. 104105. Date of Electronic Publication: 2020 Nov 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endothelial Cells/*pathology
Endothelium, Vascular/*pathology
Vascular Calcification/*pathology
Animals ; Autocrine Communication ; Cellular Microenvironment ; Endothelial Cells/metabolism ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/physiopathology ; Epithelial-Mesenchymal Transition ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/pathology ; Hemodynamics ; Humans ; Mechanotransduction, Cellular ; Neovascularization, Pathologic ; Paracrine Communication ; Vascular Calcification/metabolism ; Vascular Calcification/physiopathology
Czasopismo naukowe
Tytuł :
Frontline Science: P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse.
Autorzy :
Ledderose C; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Bromberger S; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Slubowski CJ; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Sueyoshi K; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Junger WG; Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2021 Mar; Vol. 109 (3), pp. 497-508. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Immunological Synapses/*metabolism
Lymphocyte Activation/*immunology
Mitochondria/*metabolism
Receptors, Purinergic P2/*metabolism
T-Lymphocytes/*immunology
Autocrine Communication ; CD4-Positive T-Lymphocytes/immunology ; Calcium Signaling ; Cyclic AMP/metabolism ; Humans ; Jurkat Cells ; Microtubules/metabolism ; Receptors, Purinergic P2X4 ; Signal Transduction ; U937 Cells
Czasopismo naukowe
Tytuł :
FGF21 in obesity and cancer: New insights.
Autorzy :
Lu W; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University, Stony Brook, NY, 11794, USA. Electronic address: .
Li X; School of Pharmaceutical Science, Wenzhou Medical University, China; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China. Electronic address: .
Luo Y; Division of Gastroenterology and Hepatology, Department of Medicine, Stony Brook University, Stony Brook, NY, 11794, USA; School of Pharmaceutical Science, Wenzhou Medical University, China; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China; Centeer BioTherapeutics Ltd Co, Houston, TX, 77030, USA. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2021 Feb 28; Vol. 499, pp. 5-13. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Carcinoma, Hepatocellular/*pathology
Carcinoma, Pancreatic Ductal/*pathology
Fibroblast Growth Factors/*metabolism
Liver Neoplasms/*pathology
Obesity/*metabolism
Pancreatic Neoplasms/*pathology
Adipose Tissue/metabolism ; Animals ; Autocrine Communication ; Carcinoma, Hepatocellular/etiology ; Carcinoma, Hepatocellular/prevention & control ; Carcinoma, Pancreatic Ductal/etiology ; Carcinoma, Pancreatic Ductal/prevention & control ; Cell Proliferation ; Disease Models, Animal ; Energy Metabolism ; Fatty Liver/etiology ; Fatty Liver/pathology ; Fibroblast Growth Factors/genetics ; Humans ; Hypothalamus/metabolism ; Lipid Metabolism ; Liver/pathology ; Liver Neoplasms/etiology ; Liver Neoplasms/prevention & control ; Membrane Proteins/metabolism ; Mice ; Mice, Transgenic ; Obesity/complications ; Obesity/pathology ; Pancreas/pathology ; Pancreatic Neoplasms/etiology ; Pancreatic Neoplasms/prevention & control ; Paracrine Communication ; Protective Factors ; Receptor, Fibroblast Growth Factor, Type 1/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
The Wnt Effector TCF7l2 Promotes Oligodendroglial Differentiation by Repressing Autocrine BMP4-Mediated Signaling.
Autorzy :
Zhang S; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
Wang Y; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
Zhu X; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
Song L; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
Zhan X; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.
Ma E; Department of Neurology, School of Medicine, University of California, Davis, California, 95817.; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
McDonough J; Department of Biological Sciences, Kent State University, Kent, Ohio, 44242.
Fu H; Division of Life Sciences and Medicine, School of Basic Medical Sciences, University of Science and Technology of China, Anhui, China, 230027.
Cambi F; Department of Neurology, Pittsburgh University, Pittsburgh, Pennsylvania, 15260.
Grinspan J; Department of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104.
Guo F; Department of Neurology, School of Medicine, University of California, Davis, California, 95817 .; Institute for Pediatric Regenerative Medicine (IPRM), Shriners Hospitals for Children/UC Davis School of Medicine, Sacramento, California, 95817.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Feb 24; Vol. 41 (8), pp. 1650-1664. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Morphogenetic Protein 4/*metabolism
Gene Expression Regulation/*physiology
Neurogenesis/*physiology
Oligodendroglia/*cytology
Transcription Factor 7-Like 2 Protein/*metabolism
Animals ; Autocrine Communication/physiology ; Brain/cytology ; Brain/metabolism ; Cell Differentiation/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Oligodendrocyte Precursor Cells/metabolism ; Oligodendroglia/metabolism
Czasopismo naukowe

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