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Wyszukujesz frazę ""Autophagy-Related Protein 5"" wg kryterium: Temat


Tytuł:
Interactome of Arabidopsis ATG5 Suggests Functions beyond Autophagy.
Autorzy:
Elander PH; Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, 750-07 Uppsala, Sweden.
Holla S; Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, 750-07 Uppsala, Sweden.
Sabljić I; Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, 750-07 Uppsala, Sweden.
Gutierrez-Beltran E; Instituto de Bioquımica Vegetal y Fotosıntesis, Universidad de Sevilla and Consejo Superior de Investigaciones Cientıficas, 41092 Sevilla, Spain.; Departamento de Bioquimica Vegetal y Biologia Molecular, Facultad de Biologia, Universidad de Sevilla, 41012 Sevilla, Spain.
Willems P; Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium.
Bozhkov PV; Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, 750-07 Uppsala, Sweden.
Minina EA; Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, 750-07 Uppsala, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 01; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis*/metabolism
Autophagy-Related Protein 5*/genetics
Autophagy-Related Protein 5*/metabolism
Autophagy/genetics ; Chromatography, Liquid ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Autorzy:
Zheng B; Department of Orthopedic Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Sun X; Department of Orthopedic Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhang L; Department of Operating Room, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qu G; Department of General Surgery (adult), Qingdao Women and Children's Hospital, Qingdao, China.
Ren C; Department of Orthopedic Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yan P; Department of Orthopedic Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhou C; Department of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yue B; Department of Orthopedic Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.
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Źródło:
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 2024 Feb 19; Vol. 57, pp. e13152. Date of Electronic Publication: 2024 Feb 19 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Osteosarcoma*/drug therapy
Osteosarcoma*/pathology
Lung Neoplasms*
Bone Neoplasms*/drug therapy
Bone Neoplasms*/pathology
Indoles*
Quinolines*
Animals ; Humans ; Cell Proliferation ; Autophagy ; Epithelial-Mesenchymal Transition ; Cytoskeleton/metabolism ; Cell Line, Tumor ; Cell Movement ; Autophagy-Related Protein 5/pharmacology ; Autophagy-Related Protein 5/therapeutic use
Czasopismo naukowe
Tytuł:
Discovery of Small-Molecule Autophagy Inhibitors by Disrupting the Protein-Protein Interactions Involving Autophagy-Related 5.
Autorzy:
Xiang H; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
Liu R; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
Zhang X; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
An R; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Zhou M; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
Tan C; Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, China.; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China.
Li Q; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China.
Su M; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China.
Guo C; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Zhou L; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
Li Y; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
Wang R; Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2023 Feb 23; Vol. 66 (4), pp. 2457-2476. Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy*/drug effects
Autophagy-Related Protein 12*/antagonists & inhibitors
Autophagy-Related Protein 12*/chemistry
Autophagy-Related Protein 5*/antagonists & inhibitors
Autophagy-Related Protein 5*/chemistry
Autophagy-Related Proteins*/antagonists & inhibitors
Autophagy-Related Proteins*/chemistry
Autophagy-Related Proteins*/metabolism
Multiprotein Complexes*/antagonists & inhibitors
Multiprotein Complexes*/chemistry
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Microtubule-Associated Proteins/metabolism ; Models, Molecular ; Protein Conformation ; Humans ; Animals
Czasopismo naukowe
Tytuł:
Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China.
Autorzy:
Wu Q; Department of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
Ouyang Y; Department of Laboratory Medicine, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.
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Źródło:
Microbiology and immunology [Microbiol Immunol] 2024 Feb; Vol. 68 (2), pp. 47-55. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/complications
Liver Neoplasms*/genetics
Hepatitis B*/complications
Hepatitis B*/genetics
Humans ; Hepatitis B virus ; Genotype ; Gene Frequency ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide ; China ; Case-Control Studies ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Proteins/genetics
Czasopismo naukowe
Tytuł:
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Autorzy:
Xia J; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Tian Y; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Shao Z; The Third Affiliated Hospital of Zhengzhou University, Henan, PR China.
Li C; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Ding M; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Qi Y; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Xu X; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Dai K; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Wu C; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China.
Yao W; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China. Electronic address: .
Hao C; Department of Occupational and Environment Health, School of Public Health, Zhengzhou University, No. 100 Science Avenue 5, Zhengzhou 450001, Henan Province, PR China. Electronic address: .
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Źródło:
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2023 Jan 01; Vol. 249, pp. 114392. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/metabolism
Alveolar Epithelial Cells*/pathology
Autophagy-Related Protein 5*/metabolism
Connective Tissue Growth Factor*/genetics
Connective Tissue Growth Factor*/metabolism
Epithelial-Mesenchymal Transition*
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/metabolism
Silicosis*/genetics
Silicosis*/metabolism
Animals ; Mice ; Silicon Dioxide/toxicity
Czasopismo naukowe
Tytuł:
Desialylation of ATG5 by sialidase (NEU1) promotes macrophages autophagy and exacerbates inflammation under hypoxia.
Autorzy:
Zeng S; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing 400016, China.
Wen Y; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing 400016, China.
Yu C; College of Pharmacy, Chongqing Medical University, Chongqing 400016, China; Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing 400016, China. Electronic address: .
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Źródło:
Cellular signalling [Cell Signal] 2023 Dec; Vol. 112, pp. 110927. Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:
Journal Article
MeSH Terms:
Neuraminidase*/metabolism
Atherosclerosis*
Humans ; Macrophages/metabolism ; Inflammation ; Hypoxia ; Autophagy ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism
Czasopismo naukowe
Tytuł:
Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma.
Autorzy:
Xu J; Department of Pulmonary and Critical Care Medicine, Yantai Yuhuangding Hospital, No.20, Yuhuangding East Road, Zhifu District, Yantai, 264001, China.
Yu Z; Department of Anesthesiology, Yantai Yuhuangding Hospital, Yantai, 246001, China.
Liu X; Department of Pulmonary and Critical Care Medicine, Yantai Yuhuangding Hospital, No.20, Yuhuangding East Road, Zhifu District, Yantai, 264001, China. .
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Źródło:
BMC pulmonary medicine [BMC Pulm Med] 2023 Nov 02; Vol. 23 (1), pp. 422. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Lung*/pathology
Asthma*/genetics
Humans ; Animals ; Mice ; Ovalbumin/adverse effects ; Interleukin-13 ; Airway Remodeling ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/pharmacology ; Autophagy-Related Protein 5/therapeutic use ; DNA, Complementary/adverse effects ; Transforming Growth Factor beta1/metabolism ; Inflammation/drug therapy ; RNA, Small Interfering/adverse effects ; Fibrosis ; Disease Models, Animal ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł:
ATG16L2 inhibits NLRP3 inflammasome activation through promoting ATG5-12-16L1 complex assembly and autophagy.
Autorzy:
Wang D; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan T; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu J; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wen Z; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen Y; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tang J; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang Z; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wu X; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
European journal of immunology [Eur J Immunol] 2022 Aug; Vol. 52 (8), pp. 1321-1334. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy-Related Protein 5*/genetics
Autophagy-Related Protein 5*/metabolism
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/genetics
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Animals ; Autophagy ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Comparative Genetic Analysis of the Promoters of the ATG16L1 and ATG5 Genes Associated with Sporadic Parkinson's Disease.
Autorzy:
Gómez-Martín A; Nursing Department, Faculty of Nursing and Occupational Therapy, University of Extremadura, Avda de la Universidad s/n, 10003 Cáceres, Spain.; Instituto de Investigación Biosanitaria de Extremadura (INUBE), 10003 Cáceres, Spain.
Fuentes JM; Instituto de Investigación Biosanitaria de Extremadura (INUBE), 10003 Cáceres, Spain.; Departamento de Bioquímica y Biología Molecular y Genética, Facultad de Enfermería y Terapia Ocupa-cional, Universidad de Extremadura, 10003 Cáceres, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativa, Instituto de Salus Carlos III (CIBER-CIBERNED-ISCIII), 28029 Madrid, Spain.
Jordán J; Pharmacology, Medical Sciences Department, Albacete School of Medicine, University of Castilla-La Mancha, 02008 Albacete, Spain.
Galindo MF; Pharmaceutical Technologic, Medical Sciences Department, Albacete School of Pharmacy, University of Castilla-La Mancha, 02008 Albacete, Spain.
Fernández-García JL; Animal Production and Food Science Department, Faculty of Veterinary Sciences, University of Extremadura, Avda. de la Universidad, s/n, 10003 Caceres, Spain.
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Źródło:
Genes [Genes (Basel)] 2023 Dec 02; Vol. 14 (12). Date of Electronic Publication: 2023 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Genetic Predisposition to Disease*
Parkinson Disease*/genetics
Promoter Regions, Genetic*
Humans ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Proteins/genetics ; Genotype ; Haplotypes
Czasopismo naukowe
Tytuł:
Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma.
Autorzy:
Feng Y; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Jiang Y; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Department of General Surgery (Department of Gastric Surgery Section 2, ), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Liu J; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Liu J; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Shi M; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Chen J; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Zhang J; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Tian Y; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China.; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.
Yang X; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China. .; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .
Liu H; Department of Clinical Laboratory, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Guangdong Institute of Gastroenterology, Guangzhou, 510655, China. .; Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .; Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Oct 19; Vol. 21 (1), pp. 738. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Autophagy*/drug effects
Autophagy*/genetics
Nasopharyngeal Carcinoma*/drug therapy
Nasopharyngeal Carcinoma*/genetics
Nasopharyngeal Carcinoma*/radiotherapy
Nasopharyngeal Neoplasms*/drug therapy
Nasopharyngeal Neoplasms*/genetics
Nasopharyngeal Neoplasms*/radiotherapy
Radiation Tolerance*/drug effects
Radiation Tolerance*/genetics
Replication Protein A*/antagonists & inhibitors
Replication Protein A*/genetics
Humans ; Apoptosis ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Autophagy-Related Protein 5/genetics
Czasopismo naukowe
Tytuł:
The Intrinsically Disordered N Terminus in Atg12 from Yeast Is Necessary for the Functional Structure of the Protein.
Autorzy:
Popelka H; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Lahiri V; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
Hawkins WD; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
da Veiga Leprevost F; Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Nesvizhskii AI; Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Klionsky DJ; Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 10; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy-Related Protein 12*
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Saccharomyces cerevisiae Proteins*/metabolism
Autophagy ; Autophagy-Related Protein 5 ; Autophagy-Related Proteins/genetics ; Ubiquitin/genetics ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł:
Baohuoside I inhibits resistance to cisplatin in ovarian cancer cells by suppressing autophagy via downregulating HIF-1α/ATG5 axis.
Autorzy:
Zhou Y; Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, People's Republic of China.; Department of Obstetrics and Gynecology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, Fuzhou, Fujian, People's Republic of China.
Liu T; Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, People's Republic of China.
Wu Q; Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, People's Republic of China.
Wang H; Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, People's Republic of China.
Sun Y; Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, People's Republic of China.
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Źródło:
Molecular carcinogenesis [Mol Carcinog] 2023 Oct; Vol. 62 (10), pp. 1474-1486. Date of Electronic Publication: 2023 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Animals ; Mice ; Humans ; Female ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Autophagy ; Apoptosis ; Cell Proliferation ; Autophagy-Related Protein 5
Czasopismo naukowe
Tytuł:
Is LysM-Cre a good candidate Cre for knocking out Atg5 gene in mice?
Autorzy:
Wen JH; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Li DY; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Liang S; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Tang JX; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Aug 26; Vol. 13, pp. 964496. Date of Electronic Publication: 2022 Aug 26 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy-Related Protein 5*/genetics
Animals ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Association of ATG5 gene polymorphism with Parkinson's disease in a Han Chinese population.
Autorzy:
Han J; School of Basic Medical Sciences, Xiangnan University, Chenzhou, 423000, China.
Feng G; Department of Neurology, Chenzhou First People's Hospital, Chenzhou, 423000, China.
Wu J; Department of Neurology, Chenzhou First People's Hospital, Chenzhou, 423000, China.
Zhang Y; Department of Neurology, Chenzhou First People's Hospital, Chenzhou, 423000, China.
Long Z; Department of Neurology, Chenzhou First People's Hospital, Chenzhou, 423000, China.
Yao X; Department of Neurology, Chenzhou First People's Hospital, Chenzhou, 423000, China. .
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Źródło:
Acta neurologica Belgica [Acta Neurol Belg] 2022 Aug; Vol. 122 (4), pp. 1049-1056. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy-Related Protein 5*/genetics
Parkinson Disease*/genetics
Asian People/genetics ; Case-Control Studies ; China/epidemiology ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Trehalose promotes functional recovery of keratinocytes under oxidative stress and wound healing via ATG5/ATG7.
Autorzy:
Jin J; Department of Burn Surgery, Changhai Hospital, The Second Military Medical University, Baoshan District, Shanghai, China; Shanghai Depeac Biotechnology Co., Ltd., Yangpu District, Shanghai, China.
Zhu KS; Department of Anesthesiology, Changhai Hospital, The Second Military Medical University, Baoshan District, Shanghai, China.
Tang SM; Department of Emergency, Changhai Hospital, The Second Military Medical University, Baoshan District, Shanghai, China.
Xiang Y; Department of Burn Surgery, Changhai Hospital, The Second Military Medical University, Baoshan District, Shanghai, China.
Mao MY; Shanghai Depeac Biotechnology Co., Ltd., Yangpu District, Shanghai, China.
Hong XD; Department of Burn & Plastic Surgery, 903rd Hospital of PLA (The Original 117th Hospital of People's Liberation Army), Xihu District, Hangzhou, China.
Chen AF; Department of Burn & Plastic Surgery, 903rd Hospital of PLA (The Original 117th Hospital of People's Liberation Army), Xihu District, Hangzhou, China.
Zhang XD; Department of Burn & Plastic Surgery, 903rd Hospital of PLA (The Original 117th Hospital of People's Liberation Army), Xihu District, Hangzhou, China.
Lu H; Shanghai Depeac Biotechnology Co., Ltd., Yangpu District, Shanghai, China.
Chen ZL; Shanghai Depeac Biotechnology Co., Ltd., Yangpu District, Shanghai, China.
Wu JF; Department of Burn & Plastic Surgery, 903rd Hospital of PLA (The Original 117th Hospital of People's Liberation Army), Xihu District, Hangzhou, China.
Pan SF; Department of Burns and Plastic Surgery, Zhejiang Chinese Medical University Affiliated Jiaxing TCM Hospital, Zhejiang Province, China. Electronic address: .
Zhu SH; Shanghai Depeac Biotechnology Co., Ltd., Yangpu District, Shanghai, China. Electronic address: .
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Źródło:
Burns : journal of the International Society for Burn Injuries [Burns] 2023 Sep; Vol. 49 (6), pp. 1382-1391. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Trehalose*/pharmacology
Trehalose*/metabolism
Burns*/drug therapy
Burns*/metabolism
Rats ; Animals ; Humans ; Reactive Oxygen Species/metabolism ; Hydrogen Peroxide/pharmacology ; Hydrogen Peroxide/metabolism ; Rats, Sprague-Dawley ; Keratinocytes/metabolism ; Wound Healing ; Oxidative Stress ; Necrosis ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Autophagy-Related Protein 5/pharmacology
Czasopismo naukowe
Tytuł:
LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy.
Autorzy:
Omrane M; Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris Cité, 75005 Paris, France.
Ben M'Barek K; Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris Cité, 75005 Paris, France.
Santinho A; Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris Cité, 75005 Paris, France.
Nguyen N; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.
Nag S; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.
Melia TJ; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA.
Thiam AR; Laboratoire de Physique de l'École Normale Supérieure, ENS, Université PSL, CNRS, Sorbonne Université, Université Paris Cité, 75005 Paris, France. Electronic address: .
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Źródło:
Developmental cell [Dev Cell] 2023 Jul 24; Vol. 58 (14), pp. 1266-1281.e7. Date of Electronic Publication: 2023 Jun 13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy*/genetics
Lipid Droplets*/metabolism
Animals ; Humans ; Mice ; Autophagosomes/metabolism ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism
Czasopismo naukowe
Tytuł:
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy.
Autorzy:
Wang X; Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.; Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China.
Dong FL; Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.
Wang YQ; Department of Hematology, The Third Affiliated Hospital of Shandong First Medical University, Jinan, 250014, China.
Wei HL; Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China.
Li T; Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China. .
Li J; Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Jul 20; Vol. 14 (7), pp. 451. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; RNA, Circular/genetics ; RNA, Circular/metabolism ; Cell Proliferation/genetics ; Autophagy/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism
Czasopismo naukowe
Tytuł:
Autophagy protein 5 controls flow-dependent endothelial functions.
Autorzy:
Nivoit P; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Mathivet T; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Wu J; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.; Department of Biomedical Engineering, University of Strathclyde, Glasgow, G4 ONW, UK.
Salemkour Y; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Sankar DS; Department of Biology, University of Fribourg, 1700, Fribourg, Switzerland.
Baudrie V; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Bourreau J; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.
Guihot AL; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.
Vessieres E; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.
Lemitre M; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Bocca C; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.; Département de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire d'Angers, 49500, Angers, France.
Teillon J; CNRS, Inserm, Bordeaux Imaging Center, BIC, UMS 3420, US 4, Université de Bordeaux, 33000, Bordeaux, France.
Le Gall M; Plateforme Protéomique 3P5-Proteom'IC, Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Cité, 75014, Paris, France.
Chipont A; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Robidel E; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Dhaun N; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.
Camerer E; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Reynier P; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.; Département de Biochimie et Biologie Moléculaire, Centre Hospitalier Universitaire d'Angers, 49500, Angers, France.
Roux E; Inserm, Biologie Des Maladies Cardiovasculaires, U1034, Université de Bordeaux, 33600, Pessac, France.
Couffinhal T; Inserm, Biologie Des Maladies Cardiovasculaires, U1034, Université de Bordeaux, 33600, Pessac, France.
Hadoke PWF; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH16 4TJ, UK.
Silvestre JS; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Guillonneau X; Institut de La Vision, INSERM, CNRS, Sorbonne Université, 75012, Paris, France.
Bonnin P; AP-HP, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Hypertension Unit, Université Paris Cité, 75010, Paris, France.
Henrion D; MITOVASC, CNRS UMR 6015, Inserm U1083, Université d'Angers, 49500, Angers, France.
Dengjel J; Department of Biology, University of Fribourg, 1700, Fribourg, Switzerland.
Tharaux PL; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France.
Lenoir O; Inserm, Université Paris Cité, PARCC, 56 Rue Leblanc, 75015, Paris, France. .
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Źródło:
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 Jul 18; Vol. 80 (8), pp. 210. Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells*/metabolism
Myocardial Infarction*/metabolism
Humans ; Autophagy ; Autophagy-Related Protein 5/genetics ; Autophagy-Related Protein 5/metabolism ; Endothelium, Vascular/metabolism ; Mesenteric Arteries/metabolism ; Nitric Oxide Synthase Type III/metabolism ; Signal Transduction ; Vasodilation ; Animals ; Mice
Czasopismo naukowe
Tytuł:
miR-30a-3p Regulates Autophagy in the Involution of Mice Mammary Glands.
Autorzy:
Tian L; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Guo S; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Zhao Z; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Chen Y; Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Wang C; Key Laboratory of Dairy Science of Education Ministry, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Li Q; Key Laboratory of Dairy Science of Education Ministry, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.
Li Y; School of Medicine, Kunming University of Science and Technology, Kunming 650500, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 20; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 20.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*/genetics
MicroRNAs*/genetics
Mammary Glands, Animal*/growth & development
Mammary Glands, Animal*/metabolism
Animals ; Female ; Mice ; Autophagy-Related Protein 5 ; Epithelial Cells ; Lactation/genetics
Czasopismo naukowe
Tytuł:
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy.
Autorzy:
Kaur N; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
de la Ballina LR; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Haukaas HS; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Torgersen ML; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Radulovic M; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Munson MJ; Advanced Drug Delivery, Pharmaceutical Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Sabirsh A; Advanced Drug Delivery, Pharmaceutical Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Stenmark H; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Simonsen A; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Carlsson SR; Department of Medical Biochemistry and Biophysics, University of Umeå, Umeå, Sweden.
Lystad AH; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
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Źródło:
The EMBO journal [EMBO J] 2023 Sep 04; Vol. 42 (17), pp. e113105. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sphingomyelins*
Ubiquitins*
Humans ; Autophagy-Related Protein 5/metabolism ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Autophagy ; Microtubule-Associated Proteins/metabolism ; Autophagy-Related Protein 12/metabolism ; Membrane Proteins/metabolism
Czasopismo naukowe

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