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Title :
HSP70, a Novel Regulatory Molecule in B Cell-Mediated Suppression of Autoimmune Diseases.
Authors :
Wang L; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Department of Endocrinology and Metabolism, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China; Biotherapy Research Center, Fudan University, Shanghai 200032, China.
Fu Y; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Yu B; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Jiang X; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.
Liu H; Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China.
Liu J; Department of Endocrinology and Metabolism, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Zha B; Department of Endocrinology and Metabolism, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China. Electronic address: .
Chu Y; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Biotherapy Research Center, Fudan University, Shanghai 200032, China. Electronic address: .
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Source :
Journal of molecular biology [J Mol Biol] 2021 Jan 08; Vol. 433 (1), pp. 166634. Date of Electronic Publication: 2020 Aug 26.
Publication Type :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Susceptibility*
Immunomodulation*
Autoimmune Diseases/*etiology
Autoimmune Diseases/*metabolism
B-Lymphocytes/*immunology
B-Lymphocytes/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Adoptive Transfer ; Adult ; Aged ; Animals ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/therapy ; B-Lymphocytes, Regulatory/immunology ; B-Lymphocytes, Regulatory/metabolism ; Colitis/diagnosis ; Colitis/etiology ; Colitis/metabolism ; Colitis/therapy ; Cytokines/antagonists & inhibitors ; Cytokines/metabolism ; Dextran Sulfate/adverse effects ; Disease Models, Animal ; Female ; Gene Expression Profiling ; HSP70 Heat-Shock Proteins/genetics ; Humans ; Immunohistochemistry ; Immunophenotyping ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Middle Aged
Academic Journal
Title :
B cells from Patients with Rheumatoid Arthritis Show Conserved CD39-Mediated Regulatory Function and increased CD39 Expression After Positive Response to Therapy.
Authors :
Zacca ER; Laboratorio de Inmunología. Hospital Nacional de Clínicas (HNC), Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.
Amezcua Vesely MC; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina.
Ferrero PV; Laboratorio de Inmunología. Hospital Nacional de Clínicas (HNC), Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.
Acosta CDV; Laboratorio de Inmunología. Hospital Nacional de Clínicas (HNC), Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.
Ponce NE; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina.
Bossio SN; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina.
Mussano E; Servicio de Reumatología. HNC, UNC, Córdoba, Argentina.
Onetti L; Servicio de Reumatología. HNC, UNC, Córdoba, Argentina.
Cadile I; Servicio de Reumatología. HNC, UNC, Córdoba, Argentina.
Acosta Rodríguez EV; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina.
Montes CL; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina.
Gruppi A; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, UNC, Córdoba, Argentina. Electronic address: .
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Source :
Journal of molecular biology [J Mol Biol] 2021 Jan 08; Vol. 433 (1), pp. 166687. Date of Electronic Publication: 2020 Oct 22.
Publication Type :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunomodulation*
Apyrase/*metabolism
Arthritis, Rheumatoid/*immunology
Arthritis, Rheumatoid/*metabolism
B-Lymphocytes/*immunology
B-Lymphocytes/*metabolism
Adenosine/metabolism ; Apyrase/genetics ; Arthritis, Rheumatoid/pathology ; Arthritis, Rheumatoid/therapy ; B-Lymphocytes, Regulatory/immunology ; B-Lymphocytes, Regulatory/metabolism ; Case-Control Studies ; Cytokines/biosynthesis ; Disease Management ; Disease Susceptibility ; Gene Expression ; Humans ; Lymphocyte Activation ; Lymphocyte Count ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Treatment Outcome
Academic Journal
Title :
Purification of Murine IL-10 B Cells for Analyses of Biological Functions and Transcriptomics.
Authors :
Sun J; Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-Sen University, Guangzhou, China. .
Basu U; Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. .
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 307-321.
Publication Type :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes, Regulatory/*metabolism
Cell Separation/*methods
Gene Expression Profiling/*methods
Animals ; Antigens, CD19/immunology ; B-Lymphocyte Subsets/cytology ; B-Lymphocyte Subsets/metabolism ; B-Lymphocytes/cytology ; B-Lymphocytes/metabolism ; B-Lymphocytes, Regulatory/cytology ; Cell Lineage/genetics ; Female ; Interleukin-10/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oligonucleotide Array Sequence Analysis/methods ; Transcriptome/genetics
Academic Journal
Title :
New Method for the Expansion of Highly Purified Human Regulatory Granzyme B-Expressing B Cells.
Authors :
Chesneau M; CHU Nantes, Université de Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France.; Labex IGO, Nantes, France.
Le Mai H; CHU Nantes, Université de Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France.; Labex IGO, Nantes, France.
Brouard S; CHU Nantes, Université de Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France. .; Labex IGO, Nantes, France. .; Centre d'Investigation Clinique en Biothérapie, Centre de ressources biologiques (CRB), Nantes, France. .
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 203-216.
Publication Type :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes, Regulatory/*immunology
Cell Culture Techniques/*methods
Granzymes/*isolation & purification
Apoptosis/immunology ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism ; B-Lymphocytes, Regulatory/metabolism ; Cell Proliferation ; Granzymes/immunology ; Granzymes/metabolism ; Humans ; Lymphocyte Activation ; T-Lymphocytes, Cytotoxic/immunology
Academic Journal
Title :
IL-35 Detection in B Cells at the mRNA and Protein Level.
Authors :
Mirlekar B; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Michaud D; Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Pylayeva-Gupta Y; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. .; Department of Genetics, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. .
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 125-147.
Publication Type :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*cytology
Flow Cytometry/*methods
Interleukins/*analysis
Animals ; B-Lymphocyte Subsets/cytology ; B-Lymphocyte Subsets/immunology ; B-Lymphocytes/immunology ; B-Lymphocytes, Regulatory/immunology ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay/methods ; Humans ; Interleukin-10/immunology ; Interleukins/blood ; Mice ; RNA, Messenger/analysis ; RNA, Messenger/genetics ; Reverse Transcriptase Polymerase Chain Reaction/methods
Academic Journal
Title :
Analysis of Regulatory B Cells in Experimental Autoimmune Uveitis.
Authors :
Choi JK; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health, Bethesda, MD, USA.; Department of Immunology, Jeonbuk National University Medical School, Jeonju, Jeonbuk, Republic of Korea.
Egwuagu CE; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health, Bethesda, MD, USA. .
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 437-450.
Publication Type :
Journal Article
MeSH Terms :
B-Lymphocytes, Regulatory/*pathology
Uveitis/*immunology
Uveitis/*therapy
Adoptive Transfer ; Animals ; Autoimmune Diseases/immunology ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; B-Lymphocytes, Regulatory/cytology ; B-Lymphocytes, Regulatory/immunology ; Central Nervous System Diseases ; Disease Models, Animal ; Female ; Inflammation/pathology ; Interleukin-10/immunology ; Male ; Mice ; Mice, Inbred NOD ; T-Lymphocytes, Regulatory/immunology ; Uveitis/metabolism
Academic Journal
Title :
Methods to Study the Transcriptome of Regulatory B Cells.
Authors :
Maho-Vaillant M; INSERM U1234, Normandy University, Rouen, France.; Dermatology Department, Rouen University Hospital, Rouen, France.
Calbo S; INSERM U1234, Normandy University, Rouen, France. .
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 295-305.
Publication Type :
Journal Article
MeSH Terms :
B-Lymphocytes, Regulatory/*metabolism
Gene Expression Profiling/*methods
Transcriptome/*genetics
Animals ; B-Lymphocyte Subsets/cytology ; B-Lymphocyte Subsets/metabolism ; B-Lymphocytes/cytology ; B-Lymphocytes/metabolism ; B-Lymphocytes, Regulatory/cytology ; Cell Lineage/genetics ; Humans ; Mice ; Oligonucleotide Array Sequence Analysis/methods ; Real-Time Polymerase Chain Reaction/methods
Academic Journal
Title :
Regulatory B Cells in Type 1 Diabetes.
Authors :
Boldison J; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK. .
Da Rosa LC; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.
Wong FS; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK.
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Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2270, pp. 419-435.
Publication Type :
Journal Article
MeSH Terms :
B-Lymphocytes, Regulatory/*pathology
Diabetes Mellitus, Type 1/*immunology
Animals ; Antibodies, Monoclonal/metabolism ; Antigens, CD20/metabolism ; Autoimmune Diseases/immunology ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; B-Lymphocytes, Regulatory/cytology ; B-Lymphocytes, Regulatory/immunology ; Diabetes Mellitus, Type 1/metabolism ; Disease Models, Animal ; Female ; Inflammation/pathology ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Male ; Mice ; Mice, Inbred NOD
Academic Journal
Title :
Vulnerabilities in the tumor and microenvironment in follicular lymphoma.
Authors :
Araujo-Ayala F; Department of Hematology-Oncology, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Pérez-Galán P; Department of Hematology-Oncology, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Hematological Neoplasms Program, Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.
Campo E; Department of Hematology-Oncology, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.; Hematological Neoplasms Program, Centro de Investigación Biomédica en Red-Oncología (CIBERONC), Madrid, Spain.; Hematopathology Unit, Pathology Department, Hospital Clínic of Barcelona, Barcelona, Spain.; Department of Basic Clinical Practice, University of Barcelona, Barcelona, Spain.
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Source :
Hematological oncology [Hematol Oncol] 2021 Jun; Vol. 39 Suppl 1, pp. 83-87.
Publication Type :
Journal Article; Review
MeSH Terms :
B-Lymphocytes*/immunology
B-Lymphocytes*/pathology
Cell Proliferation*
Lymphoma, Follicular*/genetics
Lymphoma, Follicular*/immunology
Lymphoma, Follicular*/pathology
Lymphoma, Follicular*/therapy
Mutation*
Tumor Microenvironment*/genetics
Tumor Microenvironment*/immunology
Cell Survival/genetics ; Cell Survival/immunology ; Humans
Academic Journal
Title :
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India.
Authors :
Nayak K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
Gottimukkala K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
Kumar S; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
Reddy ES; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India; Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, India.
Edara VV; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA; Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Kauffman R; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Floyd K; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA; Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Mantus G; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Savargaonkar D; ICMR-National Institute of Malaria Research, Dwarka, New Delhi, India.
Goel PK; Shaheed Hasan Khan Mewat Government Medical College, Nalhar, Mewat, Haryana, India.
Arora S; Department of Transfusion Medicine, Super Speciality Pediatric Hospital and Post Graduate Teaching Institute, Noida, UP, India.
Rahi M; Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Davis CW; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Deptartment of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Linderman S; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Wrammert J; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Suthar MS; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA; Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Ahmed R; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Deptartment of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.
Sharma A; ICMR-National Institute of Malaria Research, Dwarka, New Delhi, India; Structural Parasitology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India.
Murali-Krishna K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address: .
Chandele A; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India. Electronic address: .
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Source :
Virology [Virology] 2021 Jun; Vol. 558, pp. 13-21. Date of Electronic Publication: 2021 Mar 05.
Publication Type :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes*/cytology
B-Lymphocytes*/immunology
Antibodies, Neutralizing/*analysis
Antibodies, Viral/*analysis
COVID-19/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Adolescent ; Adult ; Aged ; COVID-19/epidemiology ; Humans ; Immunity, Humoral ; Immunoglobulin Isotypes/analysis ; India/epidemiology ; Male ; Middle Aged ; Pandemics ; Young Adult
Academic Journal
Title :
Co-evolution of tumor and immune cells during progression of multiple myeloma.
Authors :
Liu R; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Gao Q; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Foltz SM; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Fowles JS; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Yao L; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Wang JT; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Cao S; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Sun H; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Wendl MC; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.; Department of Genetics, Washington University in St. Louis, St. Louis, MO, USA.; Department of Mathematics, Washington University in St. Louis, St. Louis, MO, USA.
Sethuraman S; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Weerasinghe A; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Rettig MP; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Storrs EP; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Yoon CJ; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Wyczalkowski MA; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
McMichael JF; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Kohnen DR; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
King J; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Goldsmith SR; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
O'Neal J; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Fulton RS; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Fronick CC; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Ley TJ; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Jayasinghe RG; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA.
Fiala MA; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Oh ST; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; Center for Human Immunology and Immunotherapy Programs, Washington University in St. Louis, St. Louis, MO, USA.
DiPersio JF; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
Vij R; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA. .; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA. .
Ding L; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA. .; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO, USA. .; Department of Genetics, Washington University in St. Louis, St. Louis, MO, USA. .; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA. .
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Source :
Nature communications [Nat Commun] 2021 May 07; Vol. 12 (1), pp. 2559. Date of Electronic Publication: 2021 May 07.
Publication Type :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*metabolism
Gene Expression Regulation, Neoplastic/*genetics
Multiple Myeloma/*genetics
Multiple Myeloma/*immunology
Neoplasm Recurrence, Local/*genetics
Tumor Microenvironment/*immunology
Aged ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Cell Lineage ; Clonal Evolution/genetics ; Cohort Studies ; Disease Progression ; Female ; Gene Expression Regulation, Neoplastic/immunology ; Haplotypes ; Humans ; Interleukin-1beta/blood ; Interleukin-6/blood ; Male ; Mass Spectrometry ; Middle Aged ; Multigene Family ; Multiple Myeloma/blood ; Multiple Myeloma/pathology ; Mutation ; Neoplasm Recurrence, Local/blood ; Neoplasm Recurrence, Local/immunology ; Proto-Oncogene Proteins c-fos/blood ; Proto-Oncogene Proteins c-jun/blood ; RNA-Seq ; Signal Transduction/genetics ; Signal Transduction/immunology ; Single-Cell Analysis
Academic Journal
Title :
Nodal EBV-positive polymorphic B cell lymphoproliferative disorder with plasma cell differentiation: clinicopathological analysis of five cases.
Authors :
Satou A; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan. .
Tabata T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Suzuki Y; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
Sato Y; Division of Pathophysiology, Okayama University Graduate School of Health Sciences, Okayama, Japan.
Tahara I; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Mochizuki K; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Oishi N; Department of Pathology, Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Takahara T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Yoshino T; Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
Tsuzuki T; Department of Surgical Pathology, Aichi Medical University Hospital, 1-1, Yazakokarimata, Nagakute, 480-1195, Japan.
Nakamura S; Department of Pathology and Laboratory Medicine, Nagoya University Hospital, Nagoya, Japan.
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Source :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 May; Vol. 478 (5), pp. 969-976. Date of Electronic Publication: 2020 Nov 09.
Publication Type :
Journal Article
MeSH Terms :
Cell Differentiation*
B-Lymphocytes/*pathology
Epstein-Barr Virus Infections/*pathology
Herpesvirus 4, Human/*pathogenicity
Lymphoma, Large B-Cell, Diffuse/*pathology
Lymphoproliferative Disorders/*pathology
Plasma Cells/*pathology
Aged ; Aged, 80 and over ; Antirheumatic Agents/adverse effects ; B-Lymphocytes/immunology ; B-Lymphocytes/virology ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Diagnosis, Differential ; Epstein-Barr Virus Infections/genetics ; Epstein-Barr Virus Infections/immunology ; Epstein-Barr Virus Infections/virology ; Female ; Genes, Immunoglobulin Heavy Chain ; Genes, T-Cell Receptor gamma ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/immunology ; Host-Pathogen Interactions ; Humans ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/virology ; Lymphoproliferative Disorders/genetics ; Lymphoproliferative Disorders/immunology ; Lymphoproliferative Disorders/virology ; Male ; Methotrexate/adverse effects ; Plasma Cells/immunology ; Plasma Cells/virology ; Predictive Value of Tests ; Risk Factors
Academic Journal
Title :
Advances in Lupus Nephritis Pathogenesis: From Bench to Bedside.
Authors :
Obrișcă B; Department of Nephrology, Fundeni Clinical Institute, Fundeni Street 258, 022328 Bucharest, Romania.; Department of Nephrology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Sorohan B; Department of Nephrology, Fundeni Clinical Institute, Fundeni Street 258, 022328 Bucharest, Romania.; Department of Nephrology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Tuță L; Department of Nephrology, 'Ovidius' University, 900527 Constanta, Romania.
Ismail G; Department of Nephrology, Fundeni Clinical Institute, Fundeni Street 258, 022328 Bucharest, Romania.; Department of Nephrology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
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Source :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 05; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 05.
Publication Type :
Journal Article; Review
MeSH Terms :
B-Lymphocytes*/immunology
B-Lymphocytes*/pathology
Kidney*/immunology
Kidney*/pathology
Lupus Nephritis*/drug therapy
Lupus Nephritis*/immunology
Lupus Nephritis*/pathology
Immunosuppressive Agents/*therapeutic use
Humans
Academic Journal
Title :
Engineering antibody therapies for protective immunity.
Authors :
Lam N; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY.
Farber DL; Department of Surgery, Columbia University Irving Medical Center, New York, NY; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY. Electronic address: .
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Source :
The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2021 Apr; Vol. 161 (4), pp. 1358-1361. Date of Electronic Publication: 2020 Jun 24.
Publication Type :
Editorial
MeSH Terms :
Antibodies*/genetics
Antibodies*/immunology
Antibodies*/metabolism
B-Lymphocytes*/immunology
B-Lymphocytes*/metabolism
Biological Therapy*
Cell Engineering*
Protein Engineering*
COVID-19/therapy ; Communicable Disease Control ; Communicable Diseases/immunology ; Humans ; Immunization, Passive
SCR Protocol :
COVID-19 serotherapy
Editorial & Opinion
Title :
Increased B-cell activity with consumption of activated monocytes in severe COVID-19 patients.
Authors :
Kos I; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Balensiefer B; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Lesan V; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Kaddu-Mulindwa D; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Thurner L; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Christofyllakis K; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Bittenbring JT; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Ahlgrimm M; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Seiffert M; Division of Molecular Genetics, German Cancer Research Center, Heidelberg, Germany.
Wagenpfeil S; Institute for Medical Biometrics, Epidemiology and Medical Informatics, Saarland University, Homburg, Germany.
Bewarder Y; Department of Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany.
Neumann F; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Rixecker T; Department of Pulmonology, Allergology and Critical Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany.
Smola S; Institute of Virology, Saarland University Medical Center, Homburg/Saar, Germany.
Link A; Department of Cardiology, Angiology and Intensive Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany.
Krawczyk M; Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.
Lammert F; Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany.; Hannover Medical School, Hannover, Germany.
Lepper PM; Department of Pulmonology, Allergology and Critical Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany.
Bals R; Department of Pulmonology, Allergology and Critical Care Medicine, Saarland University Medical Center, Saarland University, Homburg, Germany.
Stilgenbauer S; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
Bewarder M; Internal Medicine I, Saarland University Medical Center, Homburg, Germany.
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Source :
European journal of immunology [Eur J Immunol] 2021 Jun; Vol. 51 (6), pp. 1449-1460. Date of Electronic Publication: 2021 Apr 19.
Publication Type :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes/*immunology
COVID-19/*immunology
Monocytes/*immunology
SARS-CoV-2/*immunology
Aged ; Antibodies, Viral/immunology ; B-Lymphocytes/pathology ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/pathology ; COVID-19/pathology ; Female ; Humans ; Immunoglobulin G/immunology ; Lymphocyte Count ; Male ; Middle Aged ; Monocytes/pathology ; Prospective Studies ; Severity of Illness Index
Academic Journal
Title :
A combination of the percentages of IFN-γ B cells is associated with acute hepatic rejection: a case control study.
Authors :
Zhu JQ; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Wang J; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Li XL; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Xu WL; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Lv SC; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Zhao X; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China.
Lang R; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China. .
He Q; Department of Hepatobiliary and Pancreaticosplenic Surgery, Medical Research Center, Beijing Organ Transplant Center, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing, 100020, China. .
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Source :
Journal of translational medicine [J Transl Med] 2021 May 01; Vol. 19 (1), pp. 187. Date of Electronic Publication: 2021 May 01.
Publication Type :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B-Lymphocytes*
Graft Rejection*
Case-Control Studies ; Granzymes ; Liver
Academic Journal
Title :
Protective effect of trichostatin A on CD19 regulatory B cells in heart transplantation.
Authors :
Zhou B; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Mei F; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Wu C; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Xu H; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Liu Z; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
Cui Y; Department of Cardiothoracic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, P.R. China.
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Source :
Molecular medicine reports [Mol Med Rep] 2021 May; Vol. 23 (5). Date of Electronic Publication: 2021 Mar 24.
Publication Type :
Journal Article
MeSH Terms :
Heart Transplantation*
B-Lymphocytes, Regulatory/*immunology
Hydroxamic Acids/*pharmacology
Immune Tolerance/*immunology
Animals ; Antigens, CD19/immunology ; Antigens, CD1d/immunology ; B-Lymphocytes, Regulatory/drug effects ; CD5 Antigens/immunology ; Cell Count ; Cell Lineage/drug effects ; Cell Lineage/immunology ; Disease Models, Animal ; Flow Cytometry ; Histone Deacetylase Inhibitors/pharmacology ; Humans ; Immune Tolerance/drug effects ; Mice ; Protective Agents/pharmacology
Academic Journal
Title :
Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19.
Authors :
Müller TM; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Becker E; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Wiendl M; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Schulze LL; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Voskens C; Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Völkl S; Department of Internal Medicine 5, Hematology and Clinical Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Kremer AE; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Neurath MF; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Zundler S; Department of Medicine 1 and Deutsches Zentrum Immuntherapie (DZI), University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
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Source :
Frontiers in immunology [Front Immunol] 2021 Apr 20; Vol. 12, pp. 639329. Date of Electronic Publication: 2021 Apr 20 (Print Publication: 2021).
Publication Type :
Journal Article
MeSH Terms :
B-Lymphocytes/*metabolism
COVID-19/*immunology
Integrin alpha4/*metabolism
Integrins/*metabolism
SARS-CoV-2/*immunology
T-Lymphocytes/*metabolism
Adult ; B-Lymphocytes/immunology ; Biomarkers/analysis ; COVID-19/pathology ; Female ; Humans ; Immunologic Memory/immunology ; Intestinal Mucosa/cytology ; Intestinal Mucosa/immunology ; Lymphocyte Count ; Male ; Middle Aged ; T-Lymphocytes/immunology
Academic Journal
Title :
Case Report: Complete and Fast Recovery From Severe COVID-19 in a Pemphigus Patient Treated With Rituximab.
Authors :
Sinagra JL; Molecular and Cell Biology Laboratory IDI-IRCCS, Rome, Italy.
Vedovelli C; Department of Infectious Diseases, Central Hospital of Bolzano, Bolzano, Italy.
Binazzi R; Department of Infectious Diseases, Central Hospital of Bolzano, Bolzano, Italy.
Salemme A; Molecular and Cell Biology Laboratory IDI-IRCCS, Rome, Italy.
Moro F; Molecular and Cell Biology Laboratory IDI-IRCCS, Rome, Italy.
Mazzanti C; Rare Diseases Unit, IDI-IRCCS, Rome, Italy.
Didona B; Rare Diseases Unit, IDI-IRCCS, Rome, Italy.
Di Zenzo G; Molecular and Cell Biology Laboratory IDI-IRCCS, Rome, Italy.
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Source :
Frontiers in immunology [Front Immunol] 2021 Apr 16; Vol. 12, pp. 665522. Date of Electronic Publication: 2021 Apr 16 (Print Publication: 2021).
Publication Type :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Adrenal Cortex Hormones/*therapeutic use
B-Lymphocytes/*immunology
COVID-19/*drug therapy
Pemphigus/*immunology
Rituximab/*adverse effects
Adrenal Cortex Hormones/adverse effects ; B-Lymphocytes/metabolism ; COVID-19/complications ; COVID-19/physiopathology ; Female ; Fever ; Humans ; Immunoglobulin G/immunology ; Inflammation/drug therapy ; Middle Aged ; Oxygen Inhalation Therapy ; Pemphigus/complications ; Pemphigus/drug therapy ; Rituximab/therapeutic use
Report
Title :
Extremely potent human monoclonal antibodies from COVID-19 convalescent patients.
Authors :
Andreano E; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Nicastri E; National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy.
Paciello I; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Pileri P; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Manganaro N; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Piccini G; VisMederi S.r.l, Siena, Italy.
Manenti A; VisMederi S.r.l, Siena, Italy; VisMederi Research S.r.l., Siena, Italy.
Pantano E; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Kabanova A; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy; Tumour Immunology Unit, Fondazione Toscana Life Sciences, Siena, Italy.
Troisi M; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Vacca F; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Cardamone D; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy; University of Turin, Turin, Italy.
De Santi C; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Torres JL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Benincasa L; VisMederi Research S.r.l., Siena, Italy.
Jang H; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30602, USA.
Di Genova C; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Chatham, UK.
Depau L; MedBiotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Brunetti J; MedBiotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Agrati C; National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy.
Capobianchi MR; National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy.
Castilletti C; National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy.
Emiliozzi A; Department of Medical Biotechnologies, University of Siena, Siena, Italy; Department of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of Siena, Siena, Italy.
Fabbiani M; Department of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of Siena, Siena, Italy.
Montagnani F; Department of Medical Biotechnologies, University of Siena, Siena, Italy; Department of Medical Sciences, Infectious and Tropical Diseases Unit, University Hospital of Siena, Siena, Italy.
Bracci L; MedBiotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Sautto G; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30602, USA.
Ross TM; Center for Vaccines and Immunology, University of Georgia, Athens, GA 30602, USA; Department of Infectious Diseases, University of Georgia, Athens, GA 30602, USA.
Montomoli E; VisMederi S.r.l, Siena, Italy; VisMederi Research S.r.l., Siena, Italy; Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent, Chatham, UK.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Sala C; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Ippolito G; National Institute for Infectious Diseases Lazzaro Spallanzani, IRCCS, Rome, Italy.
Rappuoli R; Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy; Faculty of Medicine, Imperial College, London, UK. Electronic address: .
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Source :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1821-1835.e16. Date of Electronic Publication: 2021 Feb 23.
Publication Type :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/immunology
COVID-19*/prevention & control
COVID-19*/therapy
Convalescence*
Antibodies, Monoclonal/*administration & dosage
Antibodies, Neutralizing/*administration & dosage
Antibodies, Viral/*administration & dosage
B-Lymphocytes/*immunology
3T3 Cells ; Animals ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Viral/isolation & purification ; B-Lymphocytes/cytology ; Chlorocebus aethiops ; Disease Models, Animal ; Female ; HEK293 Cells ; Humans ; Immunoglobulin Fc Fragments/immunology ; Male ; Mice ; Spike Glycoprotein, Coronavirus/immunology ; Vero Cells
Academic Journal

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