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Tytuł:
Regulatory B cells protect against chronic hypoxia-induced pulmonary hypertension by modulating the Tfh/Tfr immune balance.
Autorzy:
Li C; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Liu P; Department of Emergency, Key Laboratory of Pediatric Emergency Medicine of Hunan Province, Hunan Children's Hospital, Changsha, Hunan, People's Republic of China.
Yao H; Department of General Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Zhu H; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Zhang S; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Meng F; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Li S; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Li G; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Peng Y; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Gu J; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Zhu L; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Jiang Y; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.
Dai A; Department of Respiratory and Critical Care Medicine, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, People's Republic of China.; Department of Respiratory Diseases, Medical School, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.; Hunan Province Key Laboratory of Vascular Biology and Translational Medicine, Changsha, Hunan, People's Republic of China.
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Źródło:
Immunology [Immunology] 2023 Apr; Vol. 168 (4), pp. 580-596. Date of Electronic Publication: 2023 Jan 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypertension, Pulmonary*/etiology
B-Lymphocytes, Regulatory*/metabolism
Rats ; Mice ; Animals ; Rats, Sprague-Dawley ; T Follicular Helper Cells/metabolism ; Vascular Remodeling/physiology ; Lung/pathology ; Hypoxia/complications ; Hypoxia/metabolism ; Cell Proliferation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of the immune regulatory property of CD22 B cells.
Autorzy:
Yang G; Department of Otolaryngology & Allergy, Longgang Central Hospital, Shenzhen, China.
Suo L; Department of Otolaryngology, Head & Neck Surgery, Second Hospital, Shanxi Medical University, Taiyuan, China.
Hu S; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.
Liu H; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.
Wang X; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.
Xiao X; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.
Liu J; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.
Zeng X; Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, China.
Hong J; Department of Allergy, Third Affiliated Hospital, Shenzhen University, Shenzhen, China.
Guan L; Department of Allergy, Third Affiliated Hospital, Shenzhen University, Shenzhen, China.
Xue J; Department of Otolaryngology, Head & Neck Surgery, Second Hospital, Shanxi Medical University, Taiyuan, China.
Yang P; Guangdong Provincial Regional Disease Key Laboratory, Shenzhen, China.; Institute of Allergy & Immunology, Shenzhen University School of Medicine, State Key Laboratory of Respiratory Diseases Allergy Division, Shenzhen University, Shenzhen, China.; Longgang E.N.T Hospital & Shenzhen Key Laboratory of E.N.T, Institute of E.N.T Shenzhen, Shenzhen, China.
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Źródło:
Immunology [Immunology] 2022 Nov; Vol. 167 (3), pp. 328-339. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
B-Lymphocytes, Regulatory*
Interleukin-10*/metabolism
Animals ; CD4-Positive T-Lymphocytes/metabolism ; Galectins ; Lymphocyte Count ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.
Autorzy:
Zhu Y; The Biotherapy Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhang X; Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
Xie S; The Biotherapy Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Bao W; Department of Rheumatology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen J; The Biotherapy Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wu Q; Medical Research Center of Guangdong Provincial People's Hospital, Guangzhou, China.
Lai X; Department of Oncology Medicine, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Liu L; Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xiong S; Cell Biology Group, National Measurement Lab, LGC, Cambridgeshire, UK.
Peng Y; The Biotherapy Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
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Źródło:
Immunology [Immunology] 2022 Dec; Vol. 167 (4), pp. 576-589. Date of Electronic Publication: 2022 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes, Regulatory*
Colitis*
Mice ; Animals ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Oxidative Phosphorylation ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Abelson tyrosine kinase controls BCR signalling and B-cell differentiation by promoting B-cell metabolism.
Autorzy:
Luo L; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiang P; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen Q; Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China.
Chang J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jing Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Luo X; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gu H; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Huang Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen R; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kang D; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu Q; Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China.
Wang Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fang G; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhu Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Guan F; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lei J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang L; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu C; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Dai X; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło:
Immunology [Immunology] 2022 Oct; Vol. 167 (2), pp. 181-196. Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Actins*/metabolism
B-Lymphocytes*/metabolism
Fusion Proteins, bcr-abl*/metabolism
Agammaglobulinaemia Tyrosine Kinase/metabolism ; Animals ; Cell Differentiation ; Mice ; Phosphorylation ; Receptors, Antigen, B-Cell/metabolism ; Syk Kinase/genetics ; Syk Kinase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LncRNA00492 is required for marginal zone B-cell development.
Autorzy:
Wang F; Department of Biochemistry and Molecular Biology, Medical School of Southeast University, Nanjing, China.
Cui D; Biomedical Research Center of South China, Fujian Normal University, Fuzhou, China.; The Key Laboratories of Innate Immune Biology of Fujian Province, Fuzhou, China.
Zhang Q; Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing, China.
Shao Y; Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing, China.
Zheng B; Biomedical Research Center of South China, Fujian Normal University, Fuzhou, China.; The Key Laboratories of Innate Immune Biology of Fujian Province, Fuzhou, China.
Chen L; Biomedical Research Center of South China, Fujian Normal University, Fuzhou, China.; The Key Laboratories of Innate Immune Biology of Fujian Province, Fuzhou, China.
Luo Y; Department of Biochemistry and Molecular Biology, Medical School of Southeast University, Nanjing, China.
Yuan L; Department of Biochemistry and Molecular Biology, Medical School of Southeast University, Nanjing, China.; Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing, China.
Wang D; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
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Źródło:
Immunology [Immunology] 2022 Jan; Vol. 165 (1), pp. 88-98. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes/*cytology
B-Lymphocytes/*metabolism
Cell Differentiation/*genetics
Lymphopoiesis/*genetics
RNA, Long Noncoding/*genetics
Alcohol Oxidoreductases/metabolism ; Animals ; B-Lymphocytes/immunology ; Biomarkers ; Bone Marrow/immunology ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Cell Differentiation/immunology ; DNA-Binding Proteins/metabolism ; Gene Expression Regulation ; Immunophenotyping ; Mice ; Mice, Knockout ; Models, Biological ; Protein Binding ; Receptor, Notch2/metabolism ; Signal Transduction ; Spleen/cytology ; Spleen/immunology ; Spleen/metabolism ; Ubiquitination
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The role of Bruton's tyrosine kinase in the immune system and disease.
Autorzy:
McDonald C; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
Xanthopoulos C; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
Kostareli E; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
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Źródło:
Immunology [Immunology] 2021 Dec; Vol. 164 (4), pp. 722-736. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Agammaglobulinaemia Tyrosine Kinase/*metabolism
B-Lymphocytes/*enzymology
Immune System/*enzymology
Agammaglobulinaemia Tyrosine Kinase/antagonists & inhibitors ; Animals ; Autoimmune Diseases/drug therapy ; Autoimmune Diseases/enzymology ; Autoimmune Diseases/immunology ; B-Lymphocytes/drug effects ; B-Lymphocytes/immunology ; COVID-19/enzymology ; COVID-19/immunology ; Humans ; Immune System/drug effects ; Immune System/immunology ; Lymphoproliferative Disorders/drug therapy ; Lymphoproliferative Disorders/enzymology ; Lymphoproliferative Disorders/immunology ; Molecular Targeted Therapy ; Protein Kinase Inhibitors/therapeutic use ; Receptors, Antigen, B-Cell/metabolism ; Receptors, Chemokine/metabolism ; Signal Transduction ; Toll-Like Receptors/metabolism ; COVID-19 Drug Treatment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Crosstalk between B cells and neutrophils in rheumatoid arthritis.
Autorzy:
Karmakar U; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.
Vermeren S; Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.
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Źródło:
Immunology [Immunology] 2021 Dec; Vol. 164 (4), pp. 689-700. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Arthritis, Rheumatoid/*etiology
Arthritis, Rheumatoid/*metabolism
B-Lymphocytes/*immunology
B-Lymphocytes/*metabolism
Cell Communication/*immunology
Neutrophils/*immunology
Neutrophils/*metabolism
Animals ; Arthritis, Rheumatoid/pathology ; Autoantigens/immunology ; Autoimmunity ; B-Lymphocytes/pathology ; Biomarkers ; Cell Communication/genetics ; Disease Susceptibility ; Dysbiosis ; Extracellular Traps/genetics ; Extracellular Traps/immunology ; Extracellular Traps/metabolism ; Genetic Predisposition to Disease ; Humans ; Immunity ; Immunomodulation ; Neutrophils/pathology ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Critical roles of the E3 ubiquitin ligase FBW7 in B-cell response and the pathogenesis of experimental autoimmune arthritis.
Autorzy:
Feng C; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Li L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Zhou L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Li D; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Liu M; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
Han S; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.
Zheng B; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA.
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Źródło:
Immunology [Immunology] 2021 Nov; Vol. 164 (3), pp. 617-636. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis, Experimental/*immunology
B-Lymphocytes/*immunology
F-Box-WD Repeat-Containing Protein 7/*metabolism
Animals ; Arthritis, Experimental/diagnosis ; Arthritis, Experimental/pathology ; B-Lymphocytes/metabolism ; Collagen/administration & dosage ; Collagen/immunology ; F-Box-WD Repeat-Containing Protein 7/genetics ; Female ; Germinal Center/cytology ; Germinal Center/immunology ; Germinal Center/metabolism ; Humans ; Immunoglobulin Class Switching/genetics ; Immunologic Memory ; Male ; Mice ; Mice, Knockout ; Severity of Illness Index ; Ubiquitination/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis.
Autorzy:
Correale J; Institute for Neurological Research Dr Raúl Carrea, Fleni, Department of Neurology, Buenos Aires, Argentina.
Marrodan M; Institute for Neurological Research Dr Raúl Carrea, Fleni, Department of Neurology, Buenos Aires, Argentina.
Carnero Contentti E; Neuroimmunology Unit, Department of Neuroscience, Hospital Alemán, Buenos Aires, Argentina.
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Źródło:
Immunology [Immunology] 2021 Nov; Vol. 164 (3), pp. 569-586. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B-Lymphocytes, Regulatory/*immunology
Helminthiasis/*immunology
Interleukins/*metabolism
Multiple Sclerosis/*complications
T-Lymphocytes, Regulatory/*immunology
Adult ; Animals ; B-Lymphocytes, Regulatory/metabolism ; Female ; Helminthiasis/parasitology ; Helminths/immunology ; Helminths/isolation & purification ; Host-Parasite Interactions ; Humans ; Male ; Middle Aged ; Multiple Sclerosis/immunology ; T-Lymphocytes, Regulatory/metabolism ; Th1 Cells/immunology ; Th17 Cells/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A novel DOCK2 variant in siblings with severe combined immunodeficiency.
Autorzy:
Bruusgaard-Mouritsen MA; Section for Diagnostic Immunology, Department of Clinical Immunology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Masmas T; Department of Paediatrics and Adolescent Medicine, Paediatric Haematopoietic Stem Cell Transplantation and Immunodeficiency, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Borgwardt L; Center for Genomic Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Nazaryan-Petersen L; Center for Genomic Medicine, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Heilmann C; Department of Paediatrics and Adolescent Medicine, Paediatric Haematopoietic Stem Cell Transplantation and Immunodeficiency, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Madsen HO; Section for Diagnostic Immunology, Department of Clinical Immunology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Vibeke Marquart H; Section for Diagnostic Immunology, Department of Clinical Immunology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2023 Mar; Vol. 97 (3), pp. e13243. Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Letter
MeSH Terms:
Severe Combined Immunodeficiency*
Humans ; Siblings ; Guanine Nucleotide Exchange Factors ; B-Lymphocytes ; GTPase-Activating Proteins
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
mTORC1-GLUT1-mediated glucose metabolism drives hyperactivation of B cells in primary Sjogren's syndrome.
Autorzy:
Luo X; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.; Department of Rheumatology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Wu X; Clinical Biobank, Department of Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang A; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Chen Y; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Peng Y; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Deng C; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Zhao L; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Yang H; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Zhou J; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Peng L; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Wu Q; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Li M; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Zhao Y; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Zeng X; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Zhang W; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
Fei Y; Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, China.
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Źródło:
Immunology [Immunology] 2023 Mar; Vol. 168 (3), pp. 432-443. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sjogren's Syndrome*/metabolism
Humans ; Glucose Transporter Type 1/metabolism ; B-Lymphocytes ; Plasma Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expression of BCL11A in chronic lymphocytic leukaemia.
Autorzy:
Tosic N; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Ugrin M; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Marjanovic I; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Kostic T; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Vukovic V; Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Tomic K; Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Otasevic V; Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Antic D; Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.; School of Medicine, University of Belgrade, Belgrade, Serbia.
Mihaljevic B; Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia.; School of Medicine, University of Belgrade, Belgrade, Serbia.
Pavlovic S; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
Karan-Djurasevic T; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2023 Feb; Vol. 45 (1), pp. 64-71. Date of Electronic Publication: 2022 Sep 19.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Lymphocytic, Chronic, B-Cell*/diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell*/genetics
Leukemia, Lymphocytic, Chronic, B-Cell*/metabolism
Humans ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/pathology ; Prognosis ; B-Lymphocytes/pathology ; Chromosome Aberrations ; Transcription Factors/genetics ; Repressor Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeted suppression of Dpt-specific B cells in humanized Rag2- γc- mouse model of HDM allergy.
Autorzy:
Ralchev NR; The Stefan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Kerekov N; The Stefan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Mihaylova N; The Stefan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Kremlitzka M; MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.
Hristova D; Allergology Clinic, Alexander's University Hospital, Sofia, Bulgaria.
Dzhorev J; Biosystems Ltd, Sofia, Bulgaria.
Erdei A; MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.; Department of Immunology, Eötvös Loránd University, Budapest, Hungary.
Tchorbanov AI; The Stefan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.; National Institute of Immunology, Sofia, Bulgaria.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2023 Feb; Vol. 97 (2), pp. e13241. Date of Electronic Publication: 2022 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Dust Mite Allergy*/metabolism
Hypersensitivity*
Receptors, Antigen, B-Cell*/drug effects
Animals ; Humans ; Mice ; Allergens ; Antigens, Dermatophagoides ; Disease Models, Animal ; DNA-Binding Proteins ; Immunoglobulin E ; Nuclear Proteins ; B-Lymphocytes/drug effects
Czasopismo naukowe
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Tytuł:
Importance of B cells to development of regulatory T cells and prolongation of tissue allograft survival in recipients receiving autologous bone marrow transplantation.
Autorzy:
Gorczynski RM; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.; Department of Immunology Surgery, University of Toronto, Toronto, ON, Canada.
Farrokhi K; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.
Gorczynski C; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.
Sadozai H; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.
Zhu F; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.
Khatri I; Transplant Research Division, University Health Network and Toronto General Hospital, Toronto, ON, Canada.
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Źródło:
Immunology [Immunology] 2018 Jul; Vol. 154 (3), pp. 465-475. Date of Electronic Publication: 2018 Feb 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Marrow Transplantation*
Immunomodulation*
B-Lymphocytes/*immunology
Cell Communication/*immunology
Graft Survival/*immunology
T-Lymphocytes, Regulatory/*immunology
Animals ; B-Lymphocytes/metabolism ; B-Lymphocytes, Regulatory/immunology ; B-Lymphocytes, Regulatory/metabolism ; Biomarkers ; Cytotoxicity, Immunologic ; Immunoglobulin G/immunology ; Leukocytes/immunology ; Leukocytes/metabolism ; Mice ; Skin Transplantation ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes, Regulatory/metabolism ; Transplantation, Homologous
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Reduced activity of B lymphocytes, recognised by Sysmex XN-2000™ haematology analyser, predicts mortality in patients with coronavirus disease 2019.
Autorzy:
Rolla R; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Vidali M; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Puricelli C; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Scotta AM; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Pedrinelli A; Division of Internal Medicine, Department of Translational Medicine, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Pergolini P; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Pirisi M; Division of Internal Medicine, Department of Translational Medicine, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Dianzani U; Clinical Chemistry Laboratory, Department of Health Sciences, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
Rigamonti C; Division of Internal Medicine, Department of Translational Medicine, University of Eastern Piedmont Amedeo Avogadro, Novara, Italy.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2021 Feb; Vol. 43 (1), pp. e5-e8. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji:
Letter
MeSH Terms:
Automation, Laboratory/*instrumentation
B-Lymphocytes/*metabolism
COVID-19/*diagnosis
Hematology/*instrumentation
SARS-CoV-2/*isolation & purification
Aged ; Aged, 80 and over ; Automation, Laboratory/methods ; B-Lymphocytes/cytology ; Blood Cell Count ; COVID-19/epidemiology ; COVID-19/virology ; Creatinine/blood ; Epidemics ; Female ; Hematology/methods ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Patient Admission/statistics & numerical data ; Prognosis ; SARS-CoV-2/physiology
Opinia redakcyjna
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Tytuł:
Single-cell landscape and clinical outcomes of infiltrating B cells in colorectal cancer.
Autorzy:
Xia J; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Xie Z; Shanghai Fifth People's Hospital, and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Niu G; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Lu Z; Liver Cancer Institute and Department of Anesthesiology, Zhongshan Hospital, Shanghai, China.
Wang Z; Department of Immunology, School of Basic Medical Sciences, and Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Xing Y; Department of Immunology, School of Basic Medical Sciences, and Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Ren J; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.; Department of General Surgery, Northern Jiangsu People's Hospital, Yangzhou, China.
Hu Z; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Hong R; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Cao Z; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Han S; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Chu Y; Department of Immunology, School of Basic Medical Sciences, and Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Biotherapy Research Center, Fudan University, Shanghai, China.
Liu R; Shanghai Fifth People's Hospital, and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Ke C; Department of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
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Źródło:
Immunology [Immunology] 2023 Jan; Vol. 168 (1), pp. 135-151. Date of Electronic Publication: 2022 Sep 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*
Tertiary Lymphoid Structures*
Humans ; CD8-Positive T-Lymphocytes ; Prognosis ; B-Lymphocytes ; Immunoglobulin G ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
B cell signalling pathways-New targets for precision medicine in chronic lymphocytic leukaemia.
Autorzy:
Skånland SS; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Centre for B Cell Malignancies, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Karlsen L; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Centre for B Cell Malignancies, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Taskén K; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Centre for B Cell Malignancies, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
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Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2020 Nov; Vol. 92 (5), pp. e12931. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
B-Lymphocytes/*immunology
Leukemia, Lymphocytic, Chronic, B-Cell/*immunology
Precision Medicine/*methods
Receptors, Antigen, B-Cell/*immunology
Signal Transduction/*immunology
Agammaglobulinaemia Tyrosine Kinase/antagonists & inhibitors ; Agammaglobulinaemia Tyrosine Kinase/immunology ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; B-Lymphocytes/metabolism ; Class Ib Phosphatidylinositol 3-Kinase/immunology ; Class Ib Phosphatidylinositol 3-Kinase/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy ; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism ; Molecular Targeted Therapy/methods ; Receptors, Antigen, B-Cell/antagonists & inhibitors ; Receptors, Antigen, B-Cell/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Flow cytometry in the diagnosis of mature B-cell lymphoproliferative disorders.
Autorzy:
Debord C; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Wuillème S; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Eveillard M; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Theisen O; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Godon C; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Le Bris Y; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
Béné MC; Hematology Biology Department, Nantes University Hospital and CRCINA, Nantes, France.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2020 Jun; Vol. 42 Suppl 1, pp. 113-120.
Typ publikacji:
Journal Article; Review
MeSH Terms:
B-Lymphocytes*/metabolism
B-Lymphocytes*/pathology
Flow Cytometry*
Lymphoma, Large B-Cell, Diffuse*/blood
Lymphoma, Large B-Cell, Diffuse*/diagnosis
Lymphoma, Large B-Cell, Diffuse*/pathology
Lymphoma, Mantle-Cell*/blood
Lymphoma, Mantle-Cell*/diagnosis
Lymphoma, Mantle-Cell*/pathology
Biomarkers, Tumor/*blood
Neoplasm Proteins/*blood
Antigens, CD19/blood ; CD5 Antigens/blood ; Gene Expression Regulation, Neoplastic ; Humans ; Immunoglobulin Light Chains/blood
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Primary bone marrow Epstein-Barr virus-associated polymorphic B-cell lymphoproliferative disorder.
Autorzy:
Wang W; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, Texas, USA.
Mai B; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, Texas, USA.
Ali H; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, Texas, USA.
Savariya BU; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, Texas, USA.
Chen L; Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, Texas, USA.; Department of Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2022 Oct; Vol. 44 (5), pp. e224-e226. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Letter
MeSH Terms:
Epstein-Barr Virus Infections*/complications
Lymphoproliferative Disorders*/diagnosis
B-Lymphocytes ; Bone Marrow ; Herpesvirus 4, Human ; Humans
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immunometabolism shapes B cell fate and functions.
Autorzy:
Fu Y; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wang L; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Department of Endocrinology and Metabolism, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.; Biotherapy Research Center, Fudan University, Shanghai, China.
Yu B; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Xu D; School of Medicine, Shenzhen University, Shenzhen, China.; Third Affiliated Hospital of Shenzhen University, Shenzhen Luohu Hospital Group, Shenzhen, China.
Chu Y; Department of Immunology, School of Basic Medical Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Biotherapy Research Center, Fudan University, Shanghai, China.
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Źródło:
Immunology [Immunology] 2022 Aug; Vol. 166 (4), pp. 444-457. Date of Electronic Publication: 2022 May 29.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity*
Metabolic Networks and Pathways*
B-Lymphocytes ; Cell Differentiation ; Homeostasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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