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Tytuł:
Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway.
Autorzy:
Fu H; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.; Academy of Medical Sciences at Zhengzhou University, Zhengzhou, 45000, China.
Sen L; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Zhang F; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Liu S; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Wang M; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Mi H; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Liu M; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Li B; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Peng S; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Hu Z; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China.
Sun J; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China. SJJ_.
Li R; Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 45000, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Dec 04; Vol. 21 (1), pp. 466. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Mesenchymal Stem Cells*/metabolism
Oxidative Stress*
Extracellular Vesicles*
Animals ; Humans ; Rats ; Antioxidants/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Osteogenesis ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K.
Autorzy:
Du J; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China.; Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, The Second People's Hospital of Bao'an Shenzhen (Group) Shajing People's Hospital of Bao'an Shenzhen, Shenzhen, China.
Song D; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China.
Li Y; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China.
Liu J; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China.
Huang X; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China.
Li B; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China. .
Li L; School of Pharmacy, Institute of Traditional Chinese Medicine and New Pharmacy Development, Guangdong Medical University, Dongguan, China. china_.
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Źródło:
Neurotoxicity research [Neurotox Res] 2022 Feb; Vol. 40 (1), pp. 230-240. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article
MeSH Terms:
NF-E2-Related Factor 2*/metabolism
Neuroprotective Agents*/pharmacology
Oleanolic Acid*/analogs & derivatives
Oleanolic Acid*/pharmacology
Oxidative Stress*
Saponins*/pharmacology
Apoptosis ; Cell Line, Tumor ; Glutamic Acid/pharmacology ; Heme Oxygenase-1/metabolism ; Humans ; Malondialdehyde/metabolism ; Neurodegenerative Diseases ; Phosphatidylinositol 3-Kinases/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
A Glutathione Peroxidase Gene from Litopenaeus vannamei Is Involved in Oxidative Stress Responses and Pathogen Infection Resistance.
Autorzy:
Fan J; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Li B; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Hong Q; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Yan Z; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Yang X; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Lu K; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Chen G; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Wang L; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.
Chen Y; Key Laboratory for Healthy and Safe Aquaculture/Institute of Modern Aquaculture Science and Engineering (IMASE), College of Life Science, South China Normal University, Guangzhou 510631, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519000, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 05; Vol. 23 (1). Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Disease Resistance/*genetics
Glutathione Peroxidase/*genetics
Oxidative Stress/*genetics
Penaeidae/*genetics
Penaeidae/*metabolism
Animals ; Antimicrobial Peptides/genetics ; Cloning, Molecular ; Gene Expression ; Gene Knockdown Techniques ; Genetic Predisposition to Disease ; Penaeidae/microbiology ; Penaeidae/virology ; Phylogeny ; Sequence Analysis
Czasopismo naukowe
Tytuł:
Enhanced oxidative stress mediates pathological autophagy and necroptosis in cardiac myocytes in pressure overload induced heart failure in rats.
Autorzy:
Chi RF; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Li L; Shanxi Medical University, Taiyuan, China.; Department of Physiology, Shanxi Medical University, Taiyuan, China.
Wang AL; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Yang H; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Xi J; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Zhu ZF; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Wang K; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Li B; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Yang LG; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Qin FZ; The Second Hospital of Shanxi Medical University, Taiyuan, China.; Shanxi Medical University, Taiyuan, China.
Zhang C; Shanxi Medical University, Taiyuan, China.; Department of Physiology, Shanxi Medical University, Taiyuan, China.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Jan; Vol. 49 (1), pp. 60-69. Date of Electronic Publication: 2021 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy*/drug effects
Necroptosis*/drug effects
Oxidative Stress*/drug effects
Heart Failure/*pathology
Myocytes, Cardiac/*pathology
Acetylcysteine/pharmacology ; Animals ; Blood Pressure ; Echocardiography ; Heart Failure/metabolism ; Heart Failure/physiopathology ; Male ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/physiology ; Rats ; Rats, Sprague-Dawley ; Ventricular Dysfunction, Left
Czasopismo naukowe
Tytuł:
Capillin protects against non-alcoholic steatohepatitis through suppressing NLRP3 inflammasome activation and oxidative stress.
Autorzy:
Li B; Department of Hepatology, Zaozhuang Hospital of Chinese Medicine, Zaozhuang, Shandong, China.
Wang R; Department of Gastroenterology, Zaozhuang Hospital of Chinese Medicine, Zaozhuang, Shandong, China.
Wang L; Department of Hepatology, Zaozhuang Hospital of Chinese Medicine, Zaozhuang, Shandong, China.
Zhang G; Department of Hepatology, Zaozhuang Hospital of Chinese Medicine, Zaozhuang, Shandong, China.
Zhang Y; Department of Hepatology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong, China.
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Źródło:
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2021 Dec; Vol. 43 (6), pp. 778-789. Date of Electronic Publication: 2021 Oct 07.
Typ publikacji:
Journal Article
MeSH Terms:
Diynes/*therapeutic use
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Non-alcoholic Fatty Liver Disease/*prevention & control
Oxidative Stress/*drug effects
Plant Extracts/*therapeutic use
Animals ; Diet, High-Fat/adverse effects ; Diynes/pharmacology ; Dose-Response Relationship, Drug ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism ; Oxidative Stress/physiology ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Neurotoxicity and Underlying Mechanisms of Endogenous Neurotoxins.
Autorzy:
Cao Y; Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Li B; Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.; Advanced Research Institute of Multidisciplinary Science, Beijing Institute of Technology, Beijing 100081, China.
Ismail N; Neuroimmunology, Stress and Endocrinology (NISE) Lab, School of Psychology, Faculty of Social Science, University of Ottawa, Ottawa, ON K1N 6N5, Canada.; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Smith K; Neuroimmunology, Stress and Endocrinology (NISE) Lab, School of Psychology, Faculty of Social Science, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Li T; Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.; Advanced Research Institute of Multidisciplinary Science, Beijing Institute of Technology, Beijing 100081, China.
Dai R; Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Deng Y; Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 26; Vol. 22 (23). Date of Electronic Publication: 2021 Nov 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Oxidative Stress*
Neurotoxicity Syndromes/*pathology
Neurotoxins/*adverse effects
Animals ; Humans ; Neurotoxicity Syndromes/etiology
Czasopismo naukowe
Tytuł:
Echinacoside alleviates acetaminophen-induced liver injury by attenuating oxidative stress and inflammatory cytokines in mice.
Autorzy:
Thida M; Shaanxi University of Technology, College of Biological Science and Engineering, Chinese-German Joint Laboratory for Natural Product Research, Hanzhong, Shaanxi, China.; Ministry of Education, Biotechnology Research Department, Kyaukse, Myanmar.
Li B; Shaanxi University of Technology, College of Biological Science and Engineering, Chinese-German Joint Laboratory for Natural Product Research, Hanzhong, Shaanxi, China.
Zhang X; Shaanxi University of Technology, College of Biological Science and Engineering, Chinese-German Joint Laboratory for Natural Product Research, Hanzhong, Shaanxi, China.
Chen C; Shaanxi University of Technology, College of Biological Science and Engineering, Chinese-German Joint Laboratory for Natural Product Research, Hanzhong, Shaanxi, China.
Zhang X; Shaanxi University of Technology, College of Biological Science and Engineering, Chinese-German Joint Laboratory for Natural Product Research, Hanzhong, Shaanxi, China.; University of Minho, Department of Biology, Centre of Molecular and Environmental Biology, Campus de Gualtar, Braga, Portugal.; Northwest A&F University, College of Veterinary Medicine, Yangling, China.
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Źródło:
Journal of applied biomedicine [J Appl Biomed] 2021 May; Vol. 19 (2), pp. 105-112. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chemical and Drug Induced Liver Injury*/drug therapy
Chemical and Drug Induced Liver Injury, Chronic*/drug therapy
Cytokines*/drug effects
Cytokines*/metabolism
Glycosides*/pharmacology
Glycosides*/therapeutic use
Oxidative Stress*/drug effects
Acetaminophen/adverse effects ; Animals ; Antioxidants/pharmacology ; Cytochrome P-450 CYP2E1/metabolism ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Malondialdehyde/metabolism ; Mice ; Molecular Docking Simulation ; Sulfotransferases/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Uridine Diphosphate/metabolism
Czasopismo naukowe
Tytuł:
Protective effect of hyperoside against hydrogen peroxide-induced dysfunction and oxidative stress in osteoblastic MC3T3-E1 cells.
Autorzy:
Qi XC; Department of Orthopedics, People's Hospital of Yiyuan County, Yiyuan, China.
Li B; Department of Orthopaedics, Central Hospital of Xinwen Mining Group CO., LTD, Xinwen, China.
Wu WL; Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China.
Liu HC; Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China.
Jiang YP; Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China.
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Źródło:
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 377-383.
Typ publikacji:
Journal Article; Video-Audio Media
MeSH Terms:
Hydrogen Peroxide/*pharmacology
Osteoblasts/*metabolism
Oxidative Stress/*drug effects
Quercetin/*analogs & derivatives
Animals ; Cell Line ; Mice ; Osteoblasts/pathology ; Quercetin/pharmacology
Czasopismo naukowe
Tytuł:
Melatonin protects against thoracic aortic aneurysm and dissection through SIRT1-dependent regulation of oxidative stress and vascular smooth muscle cell loss.
Autorzy:
Xia L; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Sun C; Department of Orthopedics, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhu H; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhai M; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhang L; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Jiang L; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Hou P; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Li J; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Li K; Institute of Material Medical, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
Liu Z; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Li B; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wang X; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yi W; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Liang H; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Jin Z; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yang J; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yi D; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Liu J; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yu S; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Duan W; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
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Źródło:
Journal of pineal research [J Pineal Res] 2020 Aug; Vol. 69 (1), pp. e12661. Date of Electronic Publication: 2020 May 27.
Typ publikacji:
Journal Article
MeSH Terms:
Aortic Dissection/*prevention & control
Aortic Aneurysm, Thoracic/*prevention & control
Melatonin/*pharmacology
Muscle, Smooth, Vascular/*enzymology
Myocytes, Smooth Muscle/*enzymology
Oxidative Stress/*drug effects
Sirtuin 1/*metabolism
Aortic Dissection/enzymology ; Aortic Dissection/pathology ; Animals ; Aortic Aneurysm, Thoracic/enzymology ; Aortic Aneurysm, Thoracic/pathology ; Mice ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/pathology
Czasopismo naukowe
Tytuł:
Production, Signaling, and Scavenging Mechanisms of Reactive Oxygen Species in Fruit-Pathogen Interactions.
Autorzy:
Wang Y; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
Ji D; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
Chen T; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .; Key Laboratory of Post-Harvest Handling of Fruits, Ministry of Agriculture, Beijing 100093, China. .
Li B; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .; Key Laboratory of Post-Harvest Handling of Fruits, Ministry of Agriculture, Beijing 100093, China. .
Zhang Z; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .
Qin G; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .
Tian S; Key Laboratory of Plant Resources, Institute of Botany, Innovation Academy for Seed design, Chinese Academy of Sciences, Beijing 100093, China. .; University of Chinese Academy of Sciences, Beijing 100049, China. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jun 19; Vol. 20 (12). Date of Electronic Publication: 2019 Jun 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Host-Pathogen Interactions*
Oxidative Stress*
Oxygen Radical Absorbance Capacity*
Signal Transduction*
Fruit/*metabolism
Reactive Oxygen Species/*metabolism
Disease Resistance ; Fungi ; Plant Diseases ; Plants/metabolism ; Plants/microbiology
Czasopismo naukowe
Tytuł:
Oxidative stress mediates renal endothelial cell damage in trichloroethylene-sensitized mice.
Autorzy:
Li B; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.
Xie H; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.; Institute of Dermatology, First Affiliated Hospital of Anhui Medical University, China.
Wang X; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.
Yang X; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.
Yang L; Institute of Dermatology, First Affiliated Hospital of Anhui Medical University, China.
Zhang J; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.; Institute of Dermatology, First Affiliated Hospital of Anhui Medical University, China.
Wang F; Institute of Dermatology, First Affiliated Hospital of Anhui Medical University, China.
Shen T; Department of Occupational Health and Environmental Health, School of Public Health, Anhui Medical University, China.
Zhu Q; Institute of Dermatology, First Affiliated Hospital of Anhui Medical University, China.; Key Laboratory of Dermatology, Ministry of Education, China.
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Źródło:
The Journal of toxicological sciences [J Toxicol Sci] 2019; Vol. 44 (5), pp. 317-326.
Typ publikacji:
Journal Article
MeSH Terms:
Endothelial Cells/*drug effects
Haptens/*toxicity
Kidney Diseases/*chemically induced
Oxidative Stress/*drug effects
Solvents/*toxicity
Trichloroethylene/*toxicity
Animals ; Antioxidants/pharmacology ; Cyclic N-Oxides/pharmacology ; Dermatitis, Allergic Contact/metabolism ; Dermatitis, Allergic Contact/pathology ; E-Selectin/metabolism ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Female ; Intercellular Adhesion Molecule-1/metabolism ; Kidney/drug effects ; Kidney/metabolism ; Kidney/pathology ; Kidney Diseases/metabolism ; Kidney Diseases/pathology ; Malondialdehyde/metabolism ; Mice, Inbred BALB C ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/metabolism ; Spin Labels ; Superoxide Dismutase/metabolism ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł:
Melatonin ameliorates myocardial ischemia reperfusion injury through SIRT3-dependent regulation of oxidative stress and apoptosis.
Autorzy:
Zhai M; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Li B; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Duan W; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Jing L; Cell Engineering Research Center and Department of Cell Biology, State Key Laboratory of Cancer, The Fourth Military Medical University, Xi'an, China.
Zhang B; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhang M; Institute of Material Medical, School of Pharmacy, The Fourth Military Medical University, Xi'an, China.
Yu L; Department of Cardiovascular Surgery, General Hospital of Shenyang Military Area Command, Shenyang, China.
Liu Z; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yu B; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Ren K; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Gao E; Center for Translational Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Yang Y; Department of Biomedical Engineering, The Fourth Military Medical University, Xi'an, China.
Liang H; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Jin Z; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Yu S; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
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Źródło:
Journal of pineal research [J Pineal Res] 2017 Sep; Vol. 63 (2). Date of Electronic Publication: 2017 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardial Reperfusion Injury*/drug therapy
Myocardial Reperfusion Injury*/metabolism
Myocardial Reperfusion Injury*/pathology
Apoptosis/*drug effects
Melatonin/*pharmacology
Oxidative Stress/*drug effects
Signal Transduction/*drug effects
Sirtuin 3/*metabolism
Animals ; Caspase 3/metabolism ; Male ; Mice ; Superoxide Dismutase/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Oxidative stress and hepatotoxicity in the frog, Rana chensinensis, when exposed to low doses of trichlorfon.
Autorzy:
Li B; a College of Life Science , Shaanxi Normal University , Xi'an , China.; b Research Center of Metabolic Products, Shaanxi Microbiology Institute , Xi'an , China.
Ma Y; a College of Life Science , Shaanxi Normal University , Xi'an , China.; b Research Center of Metabolic Products, Shaanxi Microbiology Institute , Xi'an , China.
Zhang YH; a College of Life Science , Shaanxi Normal University , Xi'an , China.
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Źródło:
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes [J Environ Sci Health B] 2017 Jul 03; Vol. 52 (7), pp. 476-482. Date of Electronic Publication: 2017 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Ranidae*
Insecticides/*toxicity
Liver/*drug effects
Oxidative Stress/*drug effects
Trichlorfon/*toxicity
Animals ; Antioxidants/metabolism ; Catalase/metabolism ; Dose-Response Relationship, Drug ; Ecotoxicology/methods ; Glutathione Transferase/metabolism ; Hepatocytes/drug effects ; Hepatocytes/pathology ; Insecticides/administration & dosage ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Malondialdehyde/metabolism ; Superoxide Dismutase/metabolism ; Trichlorfon/administration & dosage ; Water Pollutants, Chemical/administration & dosage ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł:
Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress.
Autorzy:
Liu Y; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
Yang H; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
Wen Y; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
Li B; The cadet brigade, the Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China. .
Zhao Y; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
Xing J; The cadet brigade, the Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, China. .
Zhang M; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
Chen Y; State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry and Emergency, School of Stomatology, the Fourth Military Medical University, 145 Changle West Road, Xi'an 710032, China. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 May 17; Vol. 18 (5). Date of Electronic Publication: 2017 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Oxidative Stress*/drug effects
NF-E2-Related Factor 2/*metabolism
Periodontal Ligament/*cytology
Stem Cells/*cytology
Stem Cells/*metabolism
Gene Expression ; Gene Silencing ; Humans ; Hydrogen Peroxide/pharmacology ; NF-E2-Related Factor 2/genetics ; Oxidation-Reduction/drug effects ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
SWATH label-free proteomics analyses revealed the roles of oxidative stress and antioxidant defensing system in sclerotia formation of Polyporus umbellatus.
Autorzy:
Li B; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Tian X; Pharmaceutical department of China-Japan Friendship Hospital, Beijing 100029 P. R. China.
Wang C; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Zeng X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Xing Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Ling H; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Yin W; Tianjin University of Science &Technology, Tianjin 300457, P. R. China.
Tian L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Meng Z; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
Zhang J; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, P. R. China.
Guo S; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100193 P. R. China.
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Źródło:
Scientific reports [Sci Rep] 2017 Jan 30; Vol. 7, pp. 41283. Date of Electronic Publication: 2017 Jan 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidative Stress*
Staining and Labeling*
Antioxidants/*metabolism
Mass Spectrometry/*methods
Polyporus/*metabolism
Proteomics/*methods
Fungal Proteins/metabolism ; Gene Ontology ; Glycerol/pharmacology ; Models, Biological ; Molecular Sequence Annotation ; Mycelium/drug effects ; Mycelium/metabolism ; Osmotic Pressure ; Polyporus/drug effects ; Principal Component Analysis ; Protein Interaction Maps ; Proteome/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Oxidative Stress Induces Mouse Follicular Granulosa Cells Apoptosis via JNK/FoxO1 Pathway.
Autorzy:
Weng Q; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Liu Z; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.; Liaoning Province of Animal Product Safety Supervision, Shenyang, China.
Li B; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Liu K; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Wu W; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Liu H; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
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Źródło:
PloS one [PLoS One] 2016 Dec 09; Vol. 11 (12), pp. e0167869. Date of Electronic Publication: 2016 Dec 09 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Oxidative Stress*
Forkhead Box Protein O1/*metabolism
Granulosa Cells/*cytology
MAP Kinase Kinase 4/*metabolism
Animals ; Female ; Humans ; Mice
Czasopismo naukowe
Tytuł:
Effective treatment of polydatin weakens the symptoms of collagen-induced arthritis in mice through its anti-oxidative and anti-inflammatory effects and the activation of MMP-9.
Autorzy:
Li B; Pediatric Surgery of Second People's Hospital of Liaocheng City, Linqing, Shandong 252600, P.R. China.
Wang XL; Pediatric Surgery of Second People's Hospital of Liaocheng City, Linqing, Shandong 252600, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 Dec; Vol. 14 (6), pp. 5357-5362. Date of Electronic Publication: 2016 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Arthritis, Experimental/*metabolism
Glucosides/*pharmacology
Matrix Metalloproteinase 9/*metabolism
Oxidative Stress/*drug effects
Stilbenes/*pharmacology
Animals ; Anti-Inflammatory Agents/chemistry ; Antioxidants/chemistry ; Arthritis, Experimental/drug therapy ; Arthritis, Experimental/pathology ; Arthritis, Rheumatoid/metabolism ; Arthritis, Rheumatoid/pathology ; Biomarkers ; Caspase 3/metabolism ; Caspase 9/metabolism ; Disease Models, Animal ; Glucosides/chemistry ; Glutathione/metabolism ; Male ; Malondialdehyde/metabolism ; Mice ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Stilbenes/chemistry ; Superoxide Dismutase/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Fibulin-3 may improve vascular health through inhibition of MMP-2/9 and oxidative stress in spontaneously hypertensive rats.
Autorzy:
Lin Z; Department of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong 510000, P.R. China.
Wang Z; Department of Pathology, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Li G; Department of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong 510000, P.R. China.
Li B; Department of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong 510000, P.R. China.
Xie W; Department of Pathology, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China.
Xiang D; Department of Cardiology, Guangzhou General Hospital of Guangzhou Military Command, Southern Medical University, Guangzhou, Guangdong 510110, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2016 May; Vol. 13 (5), pp. 3805-12. Date of Electronic Publication: 2016 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Aorta, Thoracic/*enzymology
Extracellular Matrix Proteins/*pharmacology
Matrix Metalloproteinase 2/*metabolism
Matrix Metalloproteinase 9/*metabolism
Oxidative Stress/*drug effects
Animals ; Aorta, Thoracic/pathology ; Extracellular Matrix Proteins/metabolism ; Rats ; Rats, Inbred SHR ; Rats, Inbred WKY ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Ivabradine Prevents Low Shear Stress Induced Endothelial Inflammation and Oxidative Stress via mTOR/eNOS Pathway.
Autorzy:
Li B; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 68# Changle Road, Nanjing, 210006, China.
Zhang J; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 68# Changle Road, Nanjing, 210006, China.
Wang Z; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 68# Changle Road, Nanjing, 210006, China.
Chen S; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 68# Changle Road, Nanjing, 210006, China.
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Źródło:
PloS one [PLoS One] 2016 Feb 18; Vol. 11 (2), pp. e0149694. Date of Electronic Publication: 2016 Feb 18 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stress, Mechanical*
Benzazepines/*pharmacology
Human Umbilical Vein Endothelial Cells/*pathology
Nitric Oxide Synthase Type III/*metabolism
Oxidative Stress/*drug effects
TOR Serine-Threonine Kinases/*metabolism
Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Chromones/pharmacology ; Enzyme Activation/drug effects ; Fluorescent Antibody Technique ; Gene Expression Regulation/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Inflammation/pathology ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Ivabradine ; Microscopy, Fluorescence ; Morpholines/pharmacology ; Phosphorylation/drug effects ; Phosphoserine/metabolism ; Protective Agents/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Vascular Cell Adhesion Molecule-1/genetics ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł:
In vitro toxicity evaluations of Tibetan medicine Zuota from four institutions.
Autorzy:
Li B; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Li YD; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Yang Z; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Chen Y; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Liu P; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Liu Y; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Zhang ZF; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Lv LY; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Zhang JZ; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Zeng R; a Institute of Ethnic Medicine, Southwest University for Nationalities , Chengdu , P.R. China and.
Li LM; b Sichuan Academy of Chinese Medicine Sciences , Chengdu , P.R. China.
Pokaż więcej
Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2016; Vol. 39 (2), pp. 174-81. Date of Electronic Publication: 2015 Jul 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Medicine, Tibetan Traditional*
Apoptosis/*drug effects
Drugs, Chinese Herbal/*toxicity
Gastric Juice/*chemistry
Mercury/*isolation & purification
Oxidative Stress/*drug effects
Caco-2 Cells ; Cell Survival/drug effects ; Drug Compounding ; Drugs, Chinese Herbal/chemistry ; Humans ; Microscopy, Electron, Scanning ; Models, Biological ; Surface Properties
Czasopismo naukowe

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