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Wyszukujesz frazę ""B7-H1 Antigen"" wg kryterium: Temat


Tytuł:
Programmed Death Ligand 1 Regulatory Crosstalk with Ubiquitination and Deubiquitination: Implications in Cancer Immunotherapy.
Autorzy:
Kim SB; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.
Hwang S; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
Cha JY; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
Lee HJ; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea.; Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 03; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
B7-H1 Antigen*
Neoplasms*
Humans ; Immunotherapy ; Ubiquitination ; Ubiquitin-Protein Ligases ; Ubiquitin ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Multi-cohort validation of Ascore: an anoikis-based prognostic signature for predicting disease progression and immunotherapy response in bladder cancer.
Autorzy:
Xie T; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Peng S; Department of Pathology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Liu S; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.
Zheng M; Department of Urology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Diao W; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.
Ding M; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China.
Fu Y; Department of Pathology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Guo H; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China. .
Zhao W; Department of Clinical Biochemistry School of Laboratory Medicine/Sichuan Provincial Engineering Laboratory for Prevention and Control Technology of Veterinary Drug Residue in Animal-Origin Food, Chengdu Medical College, No. 783, Xindu Rd, Chengdu, 610500, China. .
Zhuang J; Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210008, China. .; Department of Urology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China. .
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Źródło:
Molecular cancer [Mol Cancer] 2024 Feb 10; Vol. 23 (1), pp. 30. Date of Electronic Publication: 2024 Feb 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/genetics
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/therapy
Humans ; Prognosis ; Anoikis/genetics ; Disease Progression ; Immunotherapy ; Biomarkers ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
POLQ identifies a better response subset to immunotherapy in muscle-invasive bladder cancer with high PD-L1.
Autorzy:
Liu G; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Jin K; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Liu Z; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Su X; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Xu Z; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Li B; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Xu J; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Chang Y; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Wang Y; Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhu Y; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Xu L; Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xu J; NHC Key Laboratory of Glycoconjugate Research, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Wang Z; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Liu H; Department of Urology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang W; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
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Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (4), pp. e6962.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Urinary Bladder Neoplasms*/genetics
Urinary Bladder Neoplasms*/therapy
Urinary Bladder Neoplasms*/metabolism
Humans ; Biomarkers ; Immunotherapy ; Chromosomal Instability ; Muscles/metabolism ; Muscles/pathology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Targeting KDM4 family epigenetically triggers antitumour immunity via enhancing tumour-intrinsic innate sensing and immunogenicity.
Autorzy:
Sun M; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Han X; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li J; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng J; Department of Epidemiology and Biostatistics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li J; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang H; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li X; State Key Laboratory of Systems Medicine for Cancer, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1598.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Neoplasms*/drug therapy
Neoplasms*/genetics
Aminopyridines*
Hydrazones*
Humans ; Immunity, Innate/genetics ; DNA/metabolism ; Jumonji Domain-Containing Histone Demethylases/genetics
Czasopismo naukowe
Tytuł:
Enhanced tumor control activities of anti-mPD-L1 antibody and antigen-presenting cell-like natural killer cell in an allograft model.
Autorzy:
Hung YP; Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tu CC; FullHope Biomedical Co., Ltd, New Taipei City, 241405, Taiwan.
Lai JI; Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Center of Immuno-Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.
Yang MH; Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Lee JM; FullHope Biomedical Co., Ltd, New Taipei City, 241405, Taiwan. .
Chao Y; Department of Medicine, Central Clinic and Hospital, Taipei, 106441, Taiwan. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Jan 26; Vol. 24 (1), pp. 136. Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Neoplasms*
Female ; Mice ; Animals ; Mice, Inbred C57BL ; Killer Cells, Natural ; Dendritic Cells ; Allografts/metabolism ; Tumor Microenvironment ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens.
Autorzy:
Lee YH; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Huang CY; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Hsieh YH; JelloX Biotech Inc, Hsinchu, Taiwan.
Yang CH; JelloX Biotech Inc, Hsinchu, Taiwan.
Hung YL; JelloX Biotech Inc, Hsinchu, Taiwan.
Chen YA; JelloX Biotech Inc, Hsinchu, Taiwan.
Lin YC; JelloX Biotech Inc, Hsinchu, Taiwan.
Lin CH; Department of Medical Oncology, Cancer Center Branch, National Taiwan University Hospital, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.
Lee JH; Department of Oncology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan.
Wang MY; Department of Surgical Oncology, Cancer Center Branch, National Taiwan University Hospital, Taipei, Taiwan.
Kuo WH; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Lin YY; JelloX Biotech Inc, Hsinchu, Taiwan.
Lu YS; Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan. .; Department of Oncology, National Taiwan University Hospital, No.7, Chung Shan S. Rd., Zhongzheng Dist, Taipei, 100225, Taiwan. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Jan 24; Vol. 24 (1), pp. 121. Date of Electronic Publication: 2024 Jan 24.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Breast Neoplasms*
Humans ; Female ; Imaging, Three-Dimensional ; Immune Checkpoint Inhibitors ; Ligands ; Programmed Cell Death 1 Receptor ; Coloring Agents ; Computers
Czasopismo naukowe
Tytuł:
Immune characteristics and clinical significance of peripheral blood lymphocytes in breast cancer.
Autorzy:
Gao H; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Ouyang D; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.; Department of General Surgery, Xiangya Hospital Central South University, Changsha, China.
Guan X; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Xu J; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Chen Q; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Zeng L; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Pang J; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Zou Q; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China.; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China.
Qian K; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China. .; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China. .
Yi W; Department of General Surgery, The Second Xiangya Hospital, Central South University, No.139 People's Road, Changsha, Hunan, 410011, P.R. China. .; Clinical Research Center For Breast Disease In Hunan Province, Changsha, 410011, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Jan 09; Vol. 24 (1), pp. 50. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Breast Neoplasms*/therapy
Humans ; Female ; Clinical Relevance ; B-Lymphocytes ; CD4-Positive T-Lymphocytes
Czasopismo naukowe
Tytuł:
Isorhamnetin Regulates Programmed Death Ligand-1 Expression by Suppressing the EGFR-STAT3 Signaling Pathway in Canine Mammary Tumors.
Autorzy:
Mei C; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China.
Zhang X; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Zhi Y; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Liang Z; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Xu H; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Liu Z; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Liu Y; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
Lyu Y; Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China.
Wang H; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, No. 11 Shuguanghuayuan Middle Road, Haidian District, Beijing 100097, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/genetics
Quercetin*/analogs & derivatives
Breast Neoplasms*/veterinary
Animals ; Dogs ; Mice ; ErbB Receptors/genetics ; Ligands ; Signal Transduction ; STAT3 Transcription Factor
Czasopismo naukowe
Tytuł:
Prognostic value and immunological role of PD-L1 gene in pan-cancer.
Autorzy:
Wang Y; The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu, 730000, China.; General Surgery Clinical Medical Center, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China.; Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Provincial Hospital, Gansu, 730000, China.; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 204 Donggang West Road, Lanzhou, Gansu, 730000, China.
Jiang H; School of Stomatology, Lanzhou University, Lanzhou, Gansu, 730000, China.
Fu L; General Surgery Clinical Medical Center, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China.
Guan L; School of Stomatology, Lanzhou University, Lanzhou, Gansu, 730000, China.
Yang J; School of Stomatology, Lanzhou University, Lanzhou, Gansu, 730000, China.
Ren J; General Surgery Clinical Medical Center, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China.
Liu F; The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu, 730000, China.
Li X; The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu, 730000, China.
Ma X; General Surgery Clinical Medical Center, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China.
Li Y; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 204 Donggang West Road, Lanzhou, Gansu, 730000, China. .
Cai H; The First Clinical Medical College of Lanzhou University, Lanzhou, Gansu, 730000, China. .; General Surgery Clinical Medical Center, Gansu Provincial Hospital, Lanzhou, Gansu, 730000, China. .; Key Laboratory of Molecular Diagnostics and Precision Medicine for Surgical Oncology in Gansu Province, Gansu Provincial Hospital, Gansu, 730000, China. .; NHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal Tumor, Gansu Provincial Hospital, 204 Donggang West Road, Lanzhou, Gansu, 730000, China. .
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Źródło:
BMC cancer [BMC Cancer] 2024 Jan 02; Vol. 24 (1), pp. 20. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Neoplasms*/genetics
Humans ; Prognosis ; Survival Analysis ; Microsatellite Instability ; RNA, Messenger ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/analysis ; Tumor Microenvironment/genetics
Czasopismo naukowe
Tytuł:
Eliciting the antitumor immune response with a conditionally activated PD-L1 targeting antibody analyzed with a quantitative systems pharmacology model.
Autorzy:
Ippolito A; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Wang H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhang Y; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vakil V; Clinical and Quantitative Pharmacology, CytomX Therapeutics, Inc., South San Francisco, California, USA.
Bazzazi H; Clinical and Quantitative Pharmacology, CytomX Therapeutics, Inc., South San Francisco, California, USA.
Popel AS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 93-105. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/antagonists & inhibitors
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/pathology
Humans ; Antibodies/pharmacology ; Cell Line, Tumor ; Immunity ; Network Pharmacology ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Trans-Regulation of Alternative PD-L1 mRNA Processing by CDK12 in Non-Small-Cell Lung Cancer Cells.
Autorzy:
Larsen TV; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Maansson CT; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.; Department of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus, Denmark.
Daugaard TF; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
Andresen BS; Department of Biology and Molecular Biology, Southern University of Denmark, 5230 Odense, Denmark.
Sorensen BS; Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.; Department of Clinical Biochemistry, Aarhus University Hospital, 8200 Aarhus, Denmark.
Nielsen AL; Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.
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Źródło:
Cells [Cells] 2023 Dec 15; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/genetics
B7-H1 Antigen*/metabolism
Carcinoma, Non-Small-Cell Lung*/drug therapy
Cyclin-Dependent Kinases*/metabolism
Lung Neoplasms*/metabolism
Humans ; RNA Processing, Post-Transcriptional ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Tumor necrosis factor α, and agonist and antagonists of cannabinoid receptor type 1 and type 2 alter the immunophenotype of stem cells from human exfoliated deciduous teeth.
Autorzy:
Trevizani M; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Leal LL; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Rettore JVP; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Macedo GC; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Alves CCS; Faculdade de Medicina do Mucuri , Universidade Federal dos Vales do Jequitinhonha e Mucuri , Teófilo Otoni , MG , Brazil .
Castro SBR; Faculdade de Medicina do Mucuri , Universidade Federal dos Vales do Jequitinhonha e Mucuri , Teófilo Otoni , MG , Brazil .
Carmo AMRD; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Silva SAD; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Maranduba CMDC; Instituto de Ciências Biológicas , Universidade Federal de Juiz de Fora , Juiz de Fora , MG , Brazil .
Silva FS; Universidade Federal de Juiz de Fora , Governador Valadares , MG , Brazil .
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Źródło:
Einstein (Sao Paulo, Brazil) [Einstein (Sao Paulo)] 2023 Nov 13; Vol. 21, pp. eAO0405. Date of Electronic Publication: 2023 Nov 13 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
B7-H1 Antigen*/pharmacology
Tumor Necrosis Factor-alpha*
Humans ; Cell Differentiation/physiology ; Cells, Cultured ; Endocannabinoids/pharmacology ; Endocannabinoids/metabolism ; HLA-DR Antigens/metabolism ; HLA-DR Antigens/pharmacology ; Receptors, Cannabinoid/metabolism ; Stem Cells/metabolism ; Tooth, Deciduous
Czasopismo naukowe
Tytuł:
Immune checkpoint analysis in ear cancer.
Autorzy:
Klein M; Department of Oral & Maxillofacial Surgery, School of Medicine, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany. .
Polgart E; Hammer Straße 30, 48153, Münster, Germany.
Hallermann C; Laboratory for Dermatopathology and Pathology Hamburg-Niendorf, Tibarg 7, 22459, Hamburg, Germany.; Department of Dermatology and Histopathology, Fachklinik Hornheide, Dorbaumstrasse 300, 48157, Muenster, Germany.
Schulze HJ; Department of Dermatology and Histopathology, Fachklinik Hornheide, Dorbaumstrasse 300, 48157, Muenster, Germany.
Hölzle F; Department of Oral & Maxillofacial Surgery, School of Medicine, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany.
Wermker K; Department of Oral and Cranio-Maxillofacial Surgery, Klinikum Osnabrueck GmbH, Am Finkenhuegel 1, 49076, Osnabrueck, Germany.
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Źródło:
Head & face medicine [Head Face Med] 2023 Nov 06; Vol. 19 (1), pp. 48. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/analysis
B7-H1 Antigen*/metabolism
Ear Neoplasms*
Humans ; Retrospective Studies ; Lymphatic Metastasis ; Programmed Cell Death 1 Receptor ; Prognosis ; Forkhead Transcription Factors/analysis ; Forkhead Transcription Factors/metabolism ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/metabolism
Czasopismo naukowe
Tytuł:
Application of precision medicine based on next-generation sequencing and immunohistochemistry in ovarian cancer: a real-world experience.
Autorzy:
Kim YN; Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Chung YS; Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Lee JH; Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Park E; Department of Pathology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Lee ST; Department of Laboratory Medicine, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Kim S; Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Lee JY; Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea. .
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Źródło:
Journal of gynecologic oncology [J Gynecol Oncol] 2023 Nov; Vol. 34 (6), pp. e70. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Review; Journal Article
MeSH Terms:
B7-H1 Antigen*/genetics
B7-H1 Antigen*/therapeutic use
Ovarian Neoplasms*/therapy
Ovarian Neoplasms*/drug therapy
Humans ; Female ; Precision Medicine ; Immunohistochemistry ; High-Throughput Nucleotide Sequencing ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/therapeutic use ; Mutation
Czasopismo naukowe
Tytuł:
Preclinical and Clinical Observations Implying Combination Therapy to Enhance the Efficacy of the Her-2/neu B-Cell Peptide-Based Vaccine HER-Vaxx and to Prevent Immune Evasion.
Autorzy:
Tobias J; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
Högler S; Institute of Pathology, Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Raigel M; Institute of Pathology, Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Lin DS; Department of Oncology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Chao Y; Department of Oncology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Kenner L; Department of Experimental Pathology, Medical University of Vienna, 1090 Vienna, Austria.
Garner-Spitzer E; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
Yavrom S; Imugene Limited, Sydney, NSW 2000, Australia.
Ede NJ; Imugene Limited, Sydney, NSW 2000, Australia.
Zielinski CC; Central European Cancer Center, Wiener Privatklinik, and Central European Cooperative Oncology Group (CECOG), 1090 Vienna, Austria.
Kundi M; Department of Environmental Health, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.
Wiedermann U; Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 24; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Cancer Vaccines*/therapeutic use
Humans ; Animals ; Mice ; Immune Evasion ; In Situ Hybridization, Fluorescence ; Oncogenes ; Disease Progression
Czasopismo naukowe
Tytuł:
BRCA1 and BRCA2 deficient tumour models generate distinct ovarian tumour microenvironments and differential responses to therapy.
Autorzy:
Farokhi Boroujeni S; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Rodriguez G; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Galpin K; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Yakubovich E; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Murshed H; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Ibrahim D; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Asif S; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
Vanderhyden BC; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. .; Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2023 Nov 28; Vol. 16 (1), pp. 231. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/genetics
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/metabolism
Female ; Humans ; Animals ; Mice ; Tumor Microenvironment/genetics ; Genes, BRCA2 ; BRCA1 Protein/genetics ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; BRCA2 Protein/genetics
Czasopismo naukowe
Tytuł:
The Expression of Programmed Death-Ligand 1 on Immune Cells Is Related to a Better Prognosis in Biliary Tract Cancer.
Autorzy:
Kwon SC; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Bang S; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Park YN; Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Park JH; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Kim SJ; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Jo JH; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Chung MJ; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Park JY; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Park SW; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Song SY; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
Park E; Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Lee HS; Department of Internal Medicine, Institute of Gastroenterology, Seoul, Korea.
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Źródło:
Gut and liver [Gut Liver] 2023 Nov 15; Vol. 17 (6), pp. 933-941. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*
Biliary Tract Neoplasms*
Animals ; Mice ; Humans ; Prognosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Tumor microenvironment heterogeneity in bladder cancer identifies biologically distinct subtypes predicting prognosis and anti-PD-L1 responses.
Autorzy:
Li Y; Department of Urology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, Henan Province, China.
Liu Y; Department of Urology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, Henan Province, China. .
Kang Z; Department of Urology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, Henan Province, China. .
Guo J; Department of Urology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, Henan Province, China.
Liu N; Department of Urology, the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, 450000, Henan Province, China.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 10; Vol. 13 (1), pp. 19563. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/genetics
Urinary Bladder Neoplasms*/genetics
Humans ; Tumor Microenvironment/genetics ; Prognosis
Czasopismo naukowe
Tytuł:
Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway.
Autorzy:
Hodson D; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Mistry H; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Guzzetti S; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.
Davies M; DMPK, Research and Early Development, Neuroscience R&D, AstraZeneca, Cambridge, UK.
Staniszewska A; Bioscience, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.
Farrington P; Bioscience, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.
Cadogan E; Bioscience, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK.
Yates J; GlaxoSmithKline - Stevenage, Stevenage, UK.
Aarons L; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Ogungbenro K; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Nov; Vol. 12 (11), pp. 1640-1652. Date of Electronic Publication: 2023 Sep 18.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Checkpoint Inhibitors*/pharmacology
B7-H1 Antigen*
Humans ; DNA Damage
Czasopismo naukowe
Tytuł:
The Predictive Value of CD3+/CD8+ Lymphocyte Infiltration and PD-L1 Expression in Colorectal Cancer.
Autorzy:
Liu J; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
Li J; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
Luo F; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
Wu S; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
Li B; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
Liu K; Department of Pathology, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan 511518, China.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2023 Oct 31; Vol. 30 (11), pp. 9647-9659. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/metabolism
Colorectal Neoplasms*/pathology
Humans ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology
Czasopismo naukowe

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