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Tytuł :
Natural Compounds as Therapeutic Agents: The Case of Human Topoisomerase IB.
Autorzy :
Ottaviani A; Department of Biology, University of Rome Tor Vergata, Via Della Ricerca Scientifica, 00133 Rome, Italy.
Iacovelli F; Department of Biology, University of Rome Tor Vergata, Via Della Ricerca Scientifica, 00133 Rome, Italy.
Fiorani P; Department of Biology, University of Rome Tor Vergata, Via Della Ricerca Scientifica, 00133 Rome, Italy.; Institute of Translational Pharmacology, National Research Council, CNR, Via Del Fosso del Cavaliere 100, 00133 Rome, Italy.
Desideri A; Department of Biology, University of Rome Tor Vergata, Via Della Ricerca Scientifica, 00133 Rome, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 16; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*pharmacology
Biological Products/*pharmacology
Neoplasms/*drug therapy
Topoisomerase I Inhibitors/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Biological Products/chemistry ; Biological Products/therapeutic use ; Clinical Trials as Topic ; DNA Topoisomerases, Type I/chemistry ; DNA Topoisomerases, Type I/metabolism ; Humans ; Topoisomerase I Inhibitors/chemistry ; Topoisomerase I Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Synthesis of Marine Natural Products and Molecules Inspired by Marine Substances.
Autorzy :
Manzo E; Bio-Organic Chemistry Unit, Institute of Biomolecular Chemistry of the National Research Council (CNR), Via Campi Flegrei 34, 80078 Naples, Italy.
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Źródło :
Marine drugs [Mar Drugs] 2021 Apr 08; Vol. 19 (4). Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Editorial; Introductory Journal Article
MeSH Terms :
Drug Discovery*
Aquatic Organisms/*metabolism
Biological Products/*chemical synthesis
Biological Products/*isolation & purification
Biological Products/pharmacology ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Selective Discovery of GPCR Ligands within DNA-Encoded Chemical Libraries Derived from Natural Products: A Case Study on Antagonists of Angiotensin II Type I Receptor.
Autorzy :
Liang Q; College of Life Sciences, Northwest University, Xi'an 710069, China.
He J; Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Zhao X; College of Life Sciences, Northwest University, Xi'an 710069, China.
Xue Y; College of Life Sciences, Northwest University, Xi'an 710069, China.
Zuo H; College of Life Sciences, Northwest University, Xi'an 710069, China.
Xu R; College of Life Sciences, Northwest University, Xi'an 710069, China.
Jin Y; College of Life Sciences, Northwest University, Xi'an 710069, China.
Wang J; College of Life Sciences, Northwest University, Xi'an 710069, China.
Li Q; College of Life Sciences, Northwest University, Xi'an 710069, China.
Zhao X; College of Life Sciences, Northwest University, Xi'an 710069, China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Apr 08; Vol. 64 (7), pp. 4196-4205. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II Type 1 Receptor Blockers/*pharmacology
Biological Products/*pharmacology
Receptor, Angiotensin, Type 1/*metabolism
Angiotensin II Type 1 Receptor Blockers/chemistry ; Angiotensin II Type 1 Receptor Blockers/metabolism ; Animals ; Biological Products/chemistry ; Biological Products/metabolism ; DNA/chemistry ; Drug Discovery ; Ligands ; Male ; Oligodeoxyribonucleotides/chemistry ; Protein Binding ; Rats, Sprague-Dawley ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/metabolism ; Small Molecule Libraries/pharmacology
Czasopismo naukowe
Tytuł :
Whole Alga, Algal Extracts, and Compounds as Ingredients of Functional Foods: Composition and Action Mechanism Relationships in the Prevention and Treatment of Type-2 Diabetes Mellitus.
Autorzy :
Bocanegra A; Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.
Macho-González A; Nutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.; AFUSAN Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), 28040 Madrid, Spain.
Garcimartín A; Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.; AFUSAN Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), 28040 Madrid, Spain.
Benedí J; Pharmacology, Pharmacognosy and Botany Department, Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.; AFUSAN Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), 28040 Madrid, Spain.
Sánchez-Muniz FJ; Nutrition and Food Science Department (Nutrition), Pharmacy School, Complutense University of Madrid, 28040 Madrid, Spain.; AFUSAN Group, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), 28040 Madrid, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 07; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Products/*chemistry
Biological Products/*pharmacology
Food Ingredients/*analysis
Functional Food/*analysis
Hypoglycemic Agents/*chemistry
Hypoglycemic Agents/*pharmacology
Microalgae/*chemistry
Animals ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Biological Products/therapeutic use ; Biomarkers ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/metabolism ; Disease Management ; Disease Susceptibility ; Dysbiosis ; Energy Metabolism/drug effects ; Genetic Predisposition to Disease ; Humans ; Hypoglycemic Agents/therapeutic use ; Microalgae/classification ; Microbiota
Czasopismo naukowe
Tytuł :
Effect of anti-interleukin-17 biologics on Krebs von den Lungen-6 level in patients with psoriasis.
Autorzy :
Hara H; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Miyagawa H; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Araya J; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Minagawa S; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Numata T; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
Umezawa Y; Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan.
Asahina A; Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan.
Nakagawa H; Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan.
Kuwano K; Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
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Źródło :
The Journal of dermatology [J Dermatol] 2021 Jun; Vol. 48 (6), pp. 886-893. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Products*/therapeutic use
Lung Diseases, Interstitial*/diagnostic imaging
Lung Diseases, Interstitial*/drug therapy
Psoriasis*/drug therapy
Biomarkers ; Humans ; Mucin-1 ; Retrospective Studies ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Polysaccharides in natural products that repair the damage to intestinal mucosa caused by cyclophosphamide and their mechanisms: A review.
Autorzy :
Li C; Key Laboratory of Public Health Safety of Hebei Province, Ministry of Education & College of Public Health, Hebei University, Baoding, 071002, China.
Duan S; Department of Ultrasound, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, China.
Li Y; Key Laboratory of Public Health Safety of Hebei Province, Ministry of Education & College of Public Health, Hebei University, Baoding, 071002, China.
Pan X; Key Laboratory of Public Health Safety of Hebei Province, Ministry of Education & College of Public Health, Hebei University, Baoding, 071002, China.
Han L; Key Laboratory of Public Health Safety of Hebei Province, Ministry of Education & College of Public Health, Hebei University, Baoding, 071002, China. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Jun 01; Vol. 261, pp. 117876. Date of Electronic Publication: 2021 Mar 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Products/*pharmacology
Cyclophosphamide/*adverse effects
Intestinal Mucosa/*drug effects
Polysaccharides/*pharmacology
Wound Healing/*drug effects
Animals ; Antineoplastic Agents/adverse effects ; Biological Products/chemistry ; Humans ; Intestinal Mucosa/injuries ; Intestinal Mucosa/pathology ; Intestinal Mucosa/physiopathology ; Polysaccharides/isolation & purification ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
A novel challenge of nondestructive analysis on OGATA Koan's sealed medicine by muonic X-ray analysis.
Autorzy :
Shimada-Takaura K; The Museum of Osaka University, 1-13, Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan.
Ninomiya K; Graduate School of Science, Osaka University, 1-1, Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan.
Sato A; Graduate School of Science, Osaka University, 1-1, Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan.
Ueda N; Gangoji Institute for Research of Cultural Property, 146-1, Minamikainozuka-cho, Nara, Nara, 630-8304, Japan.
Tampo M; High Energy Accelerator Research Organization, 203-1, Shirakata, Tokai-Mura, Naka-gun, Ibaraki, 319-1106, Japan.
Takeshita S; High Energy Accelerator Research Organization, 203-1, Shirakata, Tokai-Mura, Naka-gun, Ibaraki, 319-1106, Japan.
Umegaki I; Toyota Central Research and Development Laboratories., Inc, 41-1, Yokomichi, Nagakute, Aichi, 480-1192, Japan.
Miyake Y; High Energy Accelerator Research Organization, 203-1, Shirakata, Tokai-Mura, Naka-gun, Ibaraki, 319-1106, Japan.
Takahashi K; The Museum of Osaka University, 1-13, Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan. .; Tekijuku Commemoration Center, Osaka University, 1-13 Machikaneyama-cho, Toyonaka, Osaka, 560-0043, Japan. .
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Źródło :
Journal of natural medicines [J Nat Med] 2021 Jun; Vol. 75 (3), pp. 532-539. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Historical Article; Journal Article
MeSH Terms :
Biological Products/*analysis
Biological Products/history ; History, 19th Century ; Humans ; Japan ; Pharmacognosy ; X-Rays
Czasopismo naukowe
Tytuł :
Additional effect of excimer light therapy in patients with psoriasis under other therapies.
Autorzy :
Ohtsuka T; Department of Dermatology, International University of Health and Welfare Hospital, Nasushiobara, Japan.
Kotani H; Department of Dermatology, International University of Health and Welfare Hospital, Nasushiobara, Japan.
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Źródło :
The Journal of dermatology [J Dermatol] 2021 Jun; Vol. 48 (6), pp. 911-915. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Products*
Psoriasis*/drug therapy
Humans ; Ointments ; Phototherapy ; Severity of Illness Index ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Psoriasis: Recent progress in molecular-targeted therapies.
Autorzy :
Honma M; Department of Dermatology, Asahikawa Medical University Hospital, Asahikawa, Japan.; International Medical Support Center, Asahikawa Medical University Hospital, Asahikawa, Japan.
Hayashi K; International Medical Support Center, Asahikawa Medical University Hospital, Asahikawa, Japan.
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Źródło :
The Journal of dermatology [J Dermatol] 2021 Jun; Vol. 48 (6), pp. 761-777. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Arthritis, Psoriatic*
Biological Products*/therapeutic use
Psoriasis*/drug therapy
Humans ; Skin ; Th17 Cells
Czasopismo naukowe
Tytuł :
Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery.
Autorzy :
Behsaz B; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, USA.; Center for Microbiome Innovation, University of California at San Diego, La Jolla, CA, USA.; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Bode E; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Gurevich A; Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St Petersburg, Russia.
Shi YN; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Grundmann F; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Acharya D; Tiny Earth Chemistry Hub, University of Wisconsin-Madison, Madison, WI, USA.
Caraballo-Rodríguez AM; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Bouslimani A; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Panitchpakdi M; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Linck A; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Guan C; The Jackson Laboratory of Medical Genomics, Farmington, CT, USA.
Oh J; The Jackson Laboratory of Medical Genomics, Farmington, CT, USA.
Dorrestein PC; Center for Microbiome Innovation, University of California at San Diego, La Jolla, CA, USA.; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Bode HB; Molecular Biotechnology, Department of Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany. .; Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt & Senckenberg Research Institute, Frankfurt am Main, Germany. .; Max-Planck-Institute for Terrestrial Microbiology, Department for Natural Products in Organismic Interactions, Marburg, Germany. .
Pevzner PA; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA. .; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. .
Mohimani H; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 28; Vol. 12 (1), pp. 3225. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Anti-Bacterial Agents/*isolation & purification
Biological Products/*isolation & purification
Computational Biology/*methods
Drug Discovery/*methods
Peptides/*isolation & purification
Algorithms ; Amino Acid Sequence/genetics ; Anti-Bacterial Agents/biosynthesis ; Biological Products/metabolism ; Datasets as Topic ; Humans ; Mass Spectrometry ; Metabolic Networks and Pathways/genetics ; Metabolomics/methods ; Metagenomics/methods ; Microbiota/genetics ; Multigene Family ; Peptide Biosynthesis ; Peptide Synthases/genetics ; Peptide Synthases/metabolism ; Peptides/genetics ; Peptides/metabolism ; Soil Microbiology
Czasopismo naukowe
Tytuł :
Progress on biosynthesis and function of the natural products of Zi Cao as a traditional Chinese medicinal herb.
Autorzy :
Lin HY; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Wang X; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
He C; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Zhou ZL; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Yang MK; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Wen ZL; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Han HW; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Lu GH; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Qi JL; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Yang YH; State Key Laboratory of Pharmaceutical Biotechnology, Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
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Źródło :
Yi chuan = Hereditas [Yi Chuan] 2021 May 20; Vol. 43 (5), pp. 459-472.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Products*
Plants, Medicinal*
China ; Plant Roots ; Prospective Studies
Czasopismo naukowe
Tytuł :
Analysis of natural compounds against the activity of SARS-CoV-2 NSP15 protein towards an effective treatment against COVID-19: a theoretical and computational biology approach.
Autorzy :
Motwalli O; College of Computing and Informatics, Saudi Electronic University (SEU), Madinah, 41538-53307, Kingdom of Saudi Arabia.
Alazmi M; College of Computer Science and Engineering, University of Ha'il, P.O. Box 2440, Ha'il, 81411, Kingdom of Saudi Arabia. .
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Źródło :
Journal of molecular modeling [J Mol Model] 2021 May 08; Vol. 27 (6), pp. 160. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/drug therapy
Computational Biology*
Endoribonucleases*/chemistry
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Viral Nonstructural Proteins*/chemistry
Antiviral Agents/*chemistry
Biological Products/*chemistry
SARS-CoV-2/*chemistry
Antiviral Agents/therapeutic use ; Biological Products/therapeutic use ; Humans
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Bacterial extracellular vesicles affect endocrine therapy in MCF7 cells.
Autorzy :
An J; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Kim JB; Research Center for Cellular Homeostasis, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu.
Yang EY; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Kim HO; Department of Nuclear Medicine, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Lee WH; MD Healthcare, Room 1303, Woori Technology Inc. building, Sangam-dong, World Cup Buk-ro 56-gil, Mapo-gu, Seoul, Republic of Korea.
Yang J; MD Healthcare, Room 1303, Woori Technology Inc. building, Sangam-dong, World Cup Buk-ro 56-gil, Mapo-gu, Seoul, Republic of Korea.
Kwon H; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Paik NS; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Lim W; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
Kim YK; MD Healthcare, Room 1303, Woori Technology Inc. building, Sangam-dong, World Cup Buk-ro 56-gil, Mapo-gu, Seoul, Republic of Korea.
Moon BI; Department of Surgery, Ewha Womans University School of Medicine, 1071 Anyangcheon-ro, Yangcheon-gu.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 May 07; Vol. 100 (18), pp. e25835.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*
Antineoplastic Agents, Hormonal/*pharmacology
Biological Products/*pharmacology
Breast Neoplasms/*drug therapy
Extracellular Vesicles/*metabolism
Antineoplastic Agents, Hormonal/therapeutic use ; Biological Products/therapeutic use ; Breast Neoplasms/pathology ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Drug Synergism ; Female ; Humans ; Klebsiella pneumoniae/cytology ; Klebsiella pneumoniae/metabolism ; MCF-7 Cells ; Tamoxifen/pharmacology ; Tamoxifen/therapeutic use ; Urine/cytology
Czasopismo naukowe
Tytuł :
Effective use of switching biologics for ulcerative colitis complicated with pyoderma gangrenosum and primary sclerosing cholangitis.
Autorzy :
Iwahashi K; Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan .
Kuroki Y; Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan.
Takano Y; Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan.
Nagahama M; Gastroenterology, Showa University Fujigaoka Hospital, Yokohama, Japan.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 May 06; Vol. 14 (5). Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Biological Products*
Cholangitis, Sclerosing*/complications
Cholangitis, Sclerosing*/drug therapy
Colitis, Ulcerative*/complications
Colitis, Ulcerative*/drug therapy
Pyoderma Gangrenosum*/complications
Pyoderma Gangrenosum*/drug therapy
Adalimumab/therapeutic use ; Adult ; Humans ; Infliximab/therapeutic use ; Male ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
Role of natural products for the treatment of Alzheimer's disease.
Autorzy :
Noori T; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Dehpour AR; Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Experimental Medicine Research Center, TUMS, Tehran, Iran.
Sureda A; Research Group on Community Nutrition and Oxidative Stress (NUCOX), University Research Institute of Health Sciences (IUNICS), and Health Research Institute of Balearic Islands (IdISBa), University of Balearic Islands, Palma de Mallorca E-07122, Balearic Islands, Spain; CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), 28029, Madrid, Spain.
Sobarzo-Sanchez E; Instituto de Investigación y Postgrado, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago, Chile; Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Spain.
Shirooie S; Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 May 05; Vol. 898, pp. 173974. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Alzheimer Disease/*drug therapy
Biological Products/*therapeutic use
Brain/*drug effects
Neuroprotective Agents/*therapeutic use
Plant Preparations/*therapeutic use
Alzheimer Disease/pathology ; Alzheimer Disease/physiopathology ; Alzheimer Disease/psychology ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Antioxidants/therapeutic use ; Biological Products/adverse effects ; Brain/pathology ; Brain/physiopathology ; Cognition/drug effects ; Disease Progression ; Humans ; Memory/drug effects ; Nerve Degeneration ; Neuroprotective Agents/adverse effects ; Nootropic Agents/therapeutic use ; Plant Preparations/adverse effects
Czasopismo naukowe
Tytuł :
Pathophysiology of moderate to severe plaque psoriasis: anti-IL-17 towards disease modification.
Autorzy :
Magina S; Department of Dermatology, Centro Hospitalar S. João, Porto, Portugal.; Department of Pharmacology and Therapeutics, Faculdade de Medicina, University of Porto, Porto, Portugal. .
Filipe P; Serviço de Dermatologia e Venereologia, Hospital de Santa Maria, Centro Hospitalar e Universitário Lisboa Norte, Lisboa, Portugal.; Unidade de Investigação em Dermatologia, Instituto de Medicina Molecular, Universidade de Lisboa, Lisboa, Portugal.; Clínica Universitária de Dermatologia, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.
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Źródło :
Drugs of today (Barcelona, Spain : 1998) [Drugs Today (Barc)] 2021 May; Vol. 57 (5), pp. 347-357.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Products*
Psoriasis*/drug therapy
Cytokines ; Humans ; Interleukin-17
Czasopismo naukowe
Tytuł :
Lactic Acid Bacteria and Natural Product Complex Ameliorates Ovalbumin-Induced Airway Hyperresponsiveness in Mice.
Autorzy :
Nam W; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Kim H; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Kim J; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Nam B; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Bae C; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Kim J; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Park S; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Lee J; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
Sim J; R&D Center, Korea Yakult Co. Ltd., Yongin, Korea.
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Źródło :
Journal of medicinal food [J Med Food] 2021 May; Vol. 24 (5), pp. 517-526.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Products*
Lactobacillales*
Animals ; Bronchoalveolar Lavage Fluid ; Cytokines ; Disease Models, Animal ; Lung ; Mice ; Mice, Inbred BALB C ; Ovalbumin ; Th2 Cells
Czasopismo naukowe
Tytuł :
Letter: vedolizumab or a second anti-TNF-no difference in efficacy for primary biologic failures with IBD. Authors' reply.
Autorzy :
Rundquist S; Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Sachs MC; Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Eriksson C; Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.; Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
Olén O; Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.; Sachs' Children and Youth Hospital, Department of Clinical Science and Education, Stockholm South General Hospital, Karolinska Institute, Stockholm, Sweden.
Montgomery S; Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.; Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.
Halfvarson J; Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
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Źródło :
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 May; Vol. 53 (9), pp. 1046-1047.
Typ publikacji :
Letter; Comment
MeSH Terms :
Biological Products*/therapeutic use
Inflammatory Bowel Diseases*/drug therapy
Pharmaceutical Preparations*
Antibodies, Monoclonal, Humanized ; Humans ; Sweden ; Tumor Necrosis Factor-alpha
Opinia redakcyjna
Tytuł :
Letter: vedolizumab or a second anti-TNF-no difference in efficacy for primary biologic failures with IBD.
Autorzy :
Demarzo MG; Gastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Bodini G; Gastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Vanello M; Gastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Martini M; Gastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Giannini EG; Gastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Pokaż więcej
Źródło :
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2021 May; Vol. 53 (9), pp. 1044-1045.
Typ publikacji :
Letter; Comment
MeSH Terms :
Biological Products*/therapeutic use
Inflammatory Bowel Diseases*/drug therapy
Pharmaceutical Preparations*
Antibodies, Monoclonal, Humanized ; Humans ; Sweden ; Tumor Necrosis Factor-alpha
Opinia redakcyjna
Tytuł :
Biological drugs in paediatric COVID-19 infection: what patients, which drug, how much and how long.
Autorzy :
Mastrolia MV; Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy.
Maccora I; Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy.
Marrani E; Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy.
Pagnini I; Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy.
Simonini G; Neurofarba Department, University of Florence, Rheumatology Unit, Meyer Children's University Hospital, Firenze, Italy. .
Pokaż więcej
Źródło :
Clinical and experimental rheumatology [Clin Exp Rheumatol] 2021 May-Jun; Vol. 39 (3), pp. 697-699. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Letter
MeSH Terms :
Biological Products*
COVID-19*
Pharmaceutical Preparations*
Child ; Humans ; SARS-CoV-2
Opinia redakcyjna

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