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Wyszukujesz frazę ""BRCA1 Protein genetics"" wg kryterium: Temat


Wyświetlanie 1-20 z 20
Tytuł :
Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations
Autorzy :
Gourley, Charlie
Hollis, Robert L.
Meynert, Alison M.
Churchman, Michael
Rye, Tzyvia
Mackean, Melanie
Nussey, Fiona
Arends, Mark J.
Sims, Andrew H.
Semple, Colin A.
Herrington, C. Simon
Pokaż więcej
Temat :
Retrospective Studies
Research Article
skin and connective tissue diseases
Doxorubicin/analogs & derivatives
Cystadenocarcinoma, Serous/drug therapy
BRCA2 Protein/genetics
endocrine system diseases
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Neoplasm Grading
BRCA1 Protein/genetics
Polymorphism, Single Nucleotide
Survival Rate
BRCA1
Female
BRCA2
Polyethylene Glycols/therapeutic use
Ovarian cancer
Ovarian Neoplasms/drug therapy
Aged
Middle Aged
Biomarkers, Tumor/genetics
Mutation
Follow-Up Studies
PLDH
RC254-282
Genetic Predisposition to Disease
Adult
Aged, 80 and over
Antibiotics, Antineoplastic/therapeutic use
Humans
Źródło :
Hollis, R L, Meynert, A, Churchman, M, Rye, T, Mackean, M, Nussey, F, Arends, M, Sims, A, Semple, C, Herrington, C & Gourley, C 2018, ' Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations ', BMC Cancer, vol. 18, no. 1, pp. 16 . https://doi.org/10.1186/s12885-017-3981-2
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Opis pliku :
application/pdf
Tytuł :
The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant:breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium
Autorzy :
Moghadasi, Setareh
Meeks, Huong D
Vreeswijk, Maaike Pg
Janssen, Linda Am
Borg, Åke
Ehrencrona, Hans
Paulsson-Karlsson, Ylva
Wappenschmidt, Barbara
Engel, Christoph
Gehrig, Andrea
Arnold, Norbert
Hansen, Thomas van Overeem
Thomassen, Mads
Jensen, Uffe Birk
Kruse, Torben A
Ejlertsen, Bent
Gerdes, Anne-Marie
Pedersen, Inge Søkilde
Caputo, Sandrine M
Couch, Fergus
Hallberg, Emily J
van den Ouweland, Ans Mw
Collée, Margriet J
Teugels, Erik
Adank, Muriel A
van der Luijt, Rob B
Mensenkamp, Arjen R
Oosterwijk, Jan C
Blok, Marinus J
Janin, Nicolas
Claes, Kathleen Bm
Tucker, Kathy
Viassolo, Valeria
Toland, Amanda Ewart
Eccles, Diana E
Devilee, Peter
Van Asperen, Christie J
Spurdle, Amanda B
Goldgar, David E
Garcia, Encarna B Gómez
Pokaż więcej
Temat :
BRCA1 Protein/genetics
Breast Neoplasms/genetics
Chromosome Segregation
Female
Genetic Predisposition to Disease
Humans
Mutation/genetics
Ovarian Neoplasms/genetics
Risk Factors
Źródło :
Moghadasi, S, Meeks, H D, Vreeswijk, M P, Janssen, L A, Borg, Å, Ehrencrona, H, Paulsson-Karlsson, Y, Wappenschmidt, B, Engel, C, Gehrig, A, Arnold, N, Hansen, T V O, Thomassen, M, Jensen, U B, Kruse, T A, Ejlertsen, B, Gerdes, A-M, Pedersen, I S, Caputo, S M, Couch, F, Hallberg, E J, van den Ouweland, A M, Collée, M J, Teugels, E, Adank, M A, van der Luijt, R B, Mensenkamp, A R, Oosterwijk, J C, Blok, M J, Janin, N, Claes, K B, Tucker, K, Viassolo, V, Toland, A E, Eccles, D E, Devilee, P, Van Asperen, C J, Spurdle, A B, Goldgar, D E & Garcia, E B G 2018, ' The BRCA1 c. 5096G >A p.Arg1699Gln (R1699Q) intermediate risk variant : breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium ', Journal of Medical Genetics, vol. 55, no. 1, pp. 15-20 . https://doi.org/10.1136/jmedgenet-2017-104560
Tytuł :
Clinical and molecular characterization of BRCA-associated breast cancer:results from the DBCG
Autorzy :
Soenderstrup, I M H
Laenkholm, A V
Jensen, M B
Eriksen, J O
Gerdes, A M
Hansen, T V O
Kruse, T A
Larsen, M J
Pedersen, I S
Rossing, M
Thomassen, M
Ejlertsen, B
Pokaż więcej
Temat :
Adolescent
Adult
Aged
BRCA1 Protein/genetics
BRCA2 Protein/genetics
Breast Neoplasms/genetics
Chemotherapy, Adjuvant
Denmark/epidemiology
Disease-Free Survival
Female
Genetic Predisposition to Disease
Heterozygote
Humans
Mastectomy
Middle Aged
Mutation
Neoplasm Recurrence, Local/genetics
Registries
Young Adult
Źródło :
Soenderstrup, I M H, Laenkholm, A V, Jensen, M B, Eriksen, J O, Gerdes, A M, Hansen, T V O, Kruse, T A, Larsen, M J, Pedersen, I S, Rossing, M, Thomassen, M & Ejlertsen, B 2018, ' Clinical and molecular characterization of BRCA-associated breast cancer : results from the DBCG ', Acta Oncologica, vol. 57, no. 1, pp. 95-101 . https://doi.org/10.1080/0284186X.2017.1398415
Tytuł :
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Autorzy :
Silvestri, Valentina
Barrowdale, Daniel
Mulligan, Anna Marie
Neuhausen, Susan L
Fox, Stephen
Karlan, Beth Y
Mitchell, Gillian
James, Paul A
Thull, Darcy L
Zorn, Kristin K
Carter, Natalie J
Nathanson, Katherine L
Domchek, Susan M
Rebbeck, Timothy R
Ramus, Susan J
Nussbaum, Robert L
Olopade, Olufunmilayo I
Rantala, Johanna
Yoon, Sook-Yee
Caligo, Maria A
Spugnesi, Laura
Bojesen, Anders
Pedersen, Inge Sokilde
Thomassen, Mads
Jensen, Uffe Birk
Toland, Amanda Ewart
Senter, Leigha
Andrulis, Irene L
Glendon, Gord
Hulick, Peter J
Imyanitov, Evgeny N
Greene, Mark H
Mai, Phuong L
Singer, Christian F
Rappaport-Fuerhauser, Christine
Kramer, Gero
Vijai, Joseph
Offit, Kenneth
Robson, Mark
Lincoln, Anne
Jacobs, Lauren
Machackova, Eva
Foretova, Lenka
Navratilova, Marie
Vasickova, Petra
Couch, Fergus J
Hallberg, Emily
Ruddy, Kathryn J.
Gerdes, Anne-Marie
Hansen, Thomas V O
Pokaż więcej
Temat :
Neoplasm Staging
Pathology
skin and connective tissue diseases
BRCA2 Protein
Breast Neoplasms
Male breast cancer
BRCA2 Protein/genetics
Càncer de mama
endocrine system diseases
FEATURES
BRCA1 Protein/genetics
Polymorphism, Single Nucleotide
Men
Genotype-phenotype correlations
Homes
Female
Breast Neoplasms/genetics
Aged
Breast cancer
Middle Aged
Histologic grade
BRCA1/2
POPULATION
Mutation
Breast Neoplasms, Male
Breast Neoplasms, Male/genetics
CARCINOMA
GRADE
BRCA1 Protein
Journal Article
RISK
Genetic Predisposition to Disease
Adult
Humans
Male
Źródło :
Silvestri, V, Barrowdale, D, Mulligan, A M, Neuhausen, S L, Fox, S, Karlan, B Y, Mitchell, G, James, P A, Thull, D L, Zorn, K K, Carter, N J, Nathanson, K L, Domchek, S M, Rebbeck, T R, Ramus, S J, Nussbaum, R L, Olopade, O I, Rantala, J, Yoon, S-Y, Caligo, M A, Spugnesi, L, Bojesen, A, Pedersen, I S, Thomassen, M, Jensen, U B, Toland, A E, Senter, L, Andrulis, I L, Glendon, G, Hulick, P J, Imyanitov, E N, Greene, M H, Mai, P L, Singer, C F, Rappaport-Fuerhauser, C, Kramer, G, Vijai, J, Offit, K, Robson, M, Lincoln, A, Jacobs, L, Machackova, E, Foretova, L, Navratilova, M, Vasickova, P, Couch, F J, Hallberg, E, Ruddy, K J, Gerdes, A-M, Hansen, T V O & kConFab Investigators 2016, ' Male breast cancer in BRCA1 and BRCA2 mutation carriers : pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 ', Breast Cancer Research (Online), vol. 18, 15 . https://doi.org/10.1186/s13058-016-0671-y
Silvestri, V, Barrowdale, D, Mulligan, A M, Neuhausen, S L, Fox, S, Karlan, B Y, Mitchell, G, James, P, Thull, D L, Zorn, K K, Carter, N J, Nathanson, K L, Dornchek, S M, Rebbeck, T R, Ramus, S J, Nussbaum, R L, Olopade, O I, Rantala, J, Yoon, S-Y, Caligo, M A, Spugnesi, L, Bojesen, A, Pedersen, I S, Thomassen, M, Jensen, U B, Toland, A E, Senter, L, Andrulis, I L, Glendon, G, Hulick, P J, Irnyanitov, E N, Greene, M H, Mai, P L, Singer, C F, Rappaport-Fuerhauser, C, Kramer, G, Vijai, J, Offit, K, Robson, M, Lincoln, A, Jacobs, L, Machackova, E, Foretova, L, Navratilova, M, Vasickova, P, Couch, F J, Hallberg, E, Ruddy, K J, Sharma, P, Kim, S-W, Hereditary Breast Ovarian Canc Res & EMBRACE 2016, ' Male breast cancer in BRCA1 and BRCA2 mutation carriers : pathology data from the Consortium of Investigators of Modifiers of BRCA1/2 ', Breast Cancer Research (Online Edition), vol. 18, no. 15, 15 . https://doi.org/10.1186/s13058-016-0671-y
Breast Cancer Research, 18(1)
Opis pliku :
application/pdf
Tytuł :
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.
Autorzy :
Lawrenson, Kate
Kar, Siddhartha
McCue, Karen
Kuchenbaeker, Karoline
Michailidou, Kyriaki
Tyrer, Jonathan
Beesley, Jonathan
Ramus, Susan J
Li, Qiyuan
Delgado, Melissa K
Lee, Janet M
Barkardottir, Rosa B
García-Closas, Montserrat
Gentry-Maharaj, Aleksandra
Torres, Diana
Hall, Per
John, Esther M
Ghoussaini, Maya
Giles, Graham G
Mazoyer, Sylvie
Wu, Anna H
Harrington, Patricia A
Laitman, Yael
Glasspool, Rosalind
Godwin, Andrew K
Goldberg, Mark S
Goldgar, David E
Høgdall, Claus K
Shah, Mitul
Johnson, Nichola
Wang-Gohrke, Shan
González-Neira, Anna
French, Juliet D
Hartman, Mikael
Terry, Mary Beth
Goodman, Marc T
Goode, Ellen L
Lambrechts, Diether
Hogervorst, Frans B L
McGuffog, Lesley
Hollestelle, Antoinette
Hopper, John L
Thomassen, Mads
Couch, Fergus J
Shen, Chen-Yang
Hulick, Peter J
Andrulis, Irene L
De Leeneer, Kim
Anton-Culver, Hoda
Kabisch, Maria
Brauch, Hiltrud
Daly, Mary B
Wentzensen, Nicolas
Kang, Daehee
Meindl, Alfons
Kapuscinski, Miroslav
McNeish, Iain
Toland, Amanda Ewart
Karlan, Beth Y
Osorio, Ana
Khan, Sofia
Kiemeney, Lambertus A
Whittemore, Alice S
Brennan, Paul
Tibiletti, Maria Grazia
Arver, Brita
Knight, Julia A
Kjaer, Susanne Kruger
Menon, Usha
Rhenius, Valerie
Lester, Jenny
Levine, Douglas A
Cox, Angela
Flyger, Henrik
Arun, Banu K
Li, Jingmei
Butzow, Ralf
Pejovic, Tanja
Lindblom, Annika
Pearce, Celeste L
Yoon, Sook-Yee
Rhiem, Kerstin
Long, Jirong
Lophatananon, Artitaya
Loud, Jennifer T
Lu, Karen
Bandera, Elisa V
Freedman, Matthew L
Cramer, Daniel W
Wildiers, Hans
Olah, Edith
Mannermaa, Arto
Lubinski, Jan
Risch, Harvey A
Peterlongo, Paolo
Shu, Xiao-Ou
Mensenkamp, Arjen R
Milne, Roger L
Easton, Douglas F
Evans, D Gareth
Hansen, Thomas V O
Montagna, Marco
Moysich, Kirsten B
Dennis, Joe
Olson, Janet E
Rodriguez, Gus
Muir, Kenneth
Mulligan, Anna Marie
Bisogna, Maria
Foretova, Lenka
Sieh, Weiva
Nathanson, Katherine L
Ness, Roberta B
Neuhausen, Susan L
Nevanlinna, Heli
Pfeiler, Georg
Brenner, Hermann
Rossing, Mary Anne
Fasching, Peter A
Barile, Monica
Orr, Nick
Cross, Simon S
Nussbaum, Robert L
Nord, Silje
Singer, Christian F
Phelan, Catherine M
Tognazzo, Silvia
Poole, Elizabeth M
Pylkäs, Katri
Cybulski, Cezary
Bruinsma, Fiona
Barrowdale, Daniel
Greene, Mark H
Slager, Susan
Gronwald, Jacek
Rudolph, Anja
Huzarski, Tomasz
Kwong, Ava
Figueroa, Jonine
Beckmann, Matthias W
Salvesen, Helga B
Tomlinson, Ian
Dansonka-Mieszkowska, Agnieszka
Sangrajrang, Suleeporn
Yannoukakos, Drakoulis
Sawyer, Elinor J
Schildkraut, Joellen M
Flesch-Janys, Dieter
Imyanitov, Evgeny N
Czene, Kamila
Schmutzler, Rita K
Schmidt, Marjanka K
Truong, Thérèse
Dunning, Alison M
Song, Honglin
Soucy, Penny
Konstantopoulou, Irene
Matsuo, Keitaro
Haiman, Christopher A
Southey, Melissa C
Zheng, Wei
Stenmark-Askmalm, Marie
Yu, Jyh-Cherng
Foulkes, William D
Pharoah, Paul D
Stoppa-Lyonnet, Dominique
Berchuck, Andrew
Sutter, Christian
Swerdlow, Anthony
Hallberg, Emily
Kosma, Veli-Matti
Fletcher, Olivia
Weitzel, Jeffrey N
Teixeira, Manuel R
Tchatchou, Sandrine
Edwards, Stacey L
Zheng, Ying
Brunet, Joan
Tseng, Chiu-Chen
Tung, Nadine
Manoukian, Siranoush
Orlow, Irene
Tworoger, Shelley S
Vachon, Celine
Le, Nhu
Blomqvist, Carl
Chenevix-Trench, Georgia
van den Ouweland, Ans M W
Bjorge, Line
Healey, Sue
Buhari, Shaik Ahmad
van Doorn, Helena C
van Rensburg, Elizabeth J
Van't Veer, Laura J
Vanderstichele, Adriaan
Khanna, Kum Kum
Isaacs, Claudine
Bogdanova, Natalia
Le Marchand, Loic
Hamann, Ute
Arndt, Volker
Vijai, Joseph
Vergote, Ignace
Burwinkel, Barbara
Blot, William
Damiola, Francesca
Simard, Jacques
Monteiro, Alvaro N
Kristensen, Vessela
Ito, Hidemi
Odunsi, Kunle
Buys, Saundra S
Offit, Kenneth
Antoniou, Antonis C
Radice, Paolo
Benitez, Javier
Margolin, Sara
Aittomäki, Kristiina
Gayther, Simon A
Darabi, Hatef
Bojesen, Anders
Fostira, Florentia
Bojesen, Stig E
Bolla, Manjeet K
Marme, Frederik
Rantala, Johanna
Kupryjanczyk, Jolanta
Børresen-Dale, Anne-Lise
Bonanni, Bernardo
Devilee, Peter
Cai, Qiuyin
Caldes, Trinidad
Sellers, Thomas A
Tihomirova, Laima
Olopade, Olufunmilayo I
Campbell, Ian
Friedman, Eitan
Canniotto, Rikki
Fridley, Brooke L
McLean, Catriona
Chang-Claude, Jenny
Hassan, Norhashimah
Chiquette, Jocelyne
Choi, Ji-Yeob
Olswold, Curtis
Seynaeve, Caroline
Massuger, Leon F A G
Feliubadalo, Lidia
Cook, Linda S
Claes, Kathleen B M
Frost, Debra
Jakubowska, Anna
Diez, Orland
Doherty, Jennifer A
Teo, Soo H
Winqvist, Robert
Domchek, Susan M
Dorfling, Cecilia M
Sinilnikova, Olga M
Herzog, Josef
Dörk, Thilo
Heitz, Florian
Park, Sue Kyung
Janavicius, Ramunas
Dumont, Martine
Ehrencrona, Hans
Ejlertsen, Bent
Ellis, Steve
Gambino, Gaetana
Rashid, Muhammad Usman
Terry, Kathryn L
O'Malley, David
Guénel, Pascal
Lee, Eunjung
Engel, Christoph
Jensen, Allan
Høgdall, Estrid
de la Hoya, Miguel
Ganz, Patricia A
Garber, Judy
Rennert, Gad
Wang, Qin
Pokaż więcej
Temat :
Brjóstakrabbamein
Arfgengi
Eggjastokkar
Krabbamein
NAF12
BRCA1 Protein/genetics
Breast Neoplasms/genetics
Chromosomes, Human, Pair 19/genetics
Genetic Predisposition to Disease
Ovarian Neoplasms/genetics
Tytuł :
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Autorzy :
Day, F.R.
Ruth, K.S.
Thompson, D.J.
Lunetta, K.L.
Pervjakova, N.
Chasman, D.I.
Stolk, L.
Finucane, H.K.
Sulem, P.
Bulik-Sullivan, B.
Esko, T.
Johnson, A.D.
Elks, C.E.
Franceschini, N.
He, C.
Altmaier, E.
Brody, J.A.
Franke, L.L.
Huffman, J.E.
Keller, M.F.
McArdle, P.F.
Nutile, T.
Porcu, E.
Robino, A.
Rose, L.M.
Schick, U.M.
Smith, J.A.
Teumer, A.
Traglia, M.
Vuckovic, D.
Yao, J.
Zhao, W.
Albrecht, E.
Amin, N.
Corre, T.
Hottenga, J.J.
Mangino, M.
Smith, A.V.
Tanaka, T.
Abecasis, G.R.
Andrulis, I.L.
Anton-Culver, H.
Antoniou, A.C.
Arndt, V.
Arnold, A.M.
Barbieri, C.
Beckmann, M.W.
Beeghly-Fadiel, A.
Benitez, J.
Bernstein, L.
Bielinski, S.J.
Blomqvist, C.
Boerwinkle, E.
Bogdanova, N.V.
Bojesen, S.E.
Bolla, M.K.
Borresen-Dale, A.L.
Boutin, T.S.
Brauch, H.
Brenner, H.
Brüning, T.
Burwinkel, B.
Campbell, A.
Campbell, H.
Chanock, S.J.
Chapman, J.R.
Chen, Y.D.
Chenevix-Trench, G.
Couch, F.J.
Coviello, A.D.
Cox, A.
Czene, K.
Darabi, H.
De Vivo, I.
Demerath, E.W.
Dennis, J.
Devilee, P.
Dörk, T.
Dos-Santos-Silva, I.
Dunning, A.M.
Eicher, J.D.
Fasching, P.A.
Faul, J.D.
Figueroa, J.
Flesch-Janys, D.
Gandin, I.
Garcia, M.E.
García-Closas, M.
Giles, G.G.
Girotto, G.G.
Goldberg, M.S.
González-Neira, A.
Goodarzi, M.O.
Grove, M.L.
Gudbjartsson, D.F.
Guénel, P.
Guo, X.
Haiman, C.A.
Hall, P.
Hamann, U.
Henderson, B.E.
Hocking, L.J.
Hofman, A.
Homuth, G.
Hooning, M.J.
Hopper, J.L.
Hu, F.B.
Huang, J.
Humphreys, K.
Hunter, D.J.
Jakubowska, A.
Jones, S.E.
Kabisch, M.
Karasik, D.
Knight, J.A.
Kolcic, I.
Kooperberg, C.
Kosma, V.M.
Kriebel, J.
Kristensen, V.
Lambrechts, D.
Langenberg, C.
Li, J.
Li, X.
Lindström, S.
Liu, Y.
Luan, J.
Lubinski, J.
Mägi, R.
Mannermaa, A.
Manz, J.
Margolin, S.
Marten, J.
Martin, N.G.
Masciullo, C.
Meindl, A.
Michailidou, K.
Mihailov, E.
Milani, L.
Milne, R.L.
Müller-Nurasyid, M.
Nalls, M.
Neale, B.M.
Nevanlinna, H.
Neven, P.
Newman, A.B.
Nordestgaard, B.G.
Olson, J.E.
Padmanabhan, S.
Peterlongo, P.
Peters, U.
Petersmann, A.
Peto, J.
Pharoah, P.D.
Pirastu, N.N.
Pirie, A.
Pistis, G.
Polasek, O.
Porteous, D.
Psaty, B.M.
Pylkäs, K.
Radice, P.
Raffel, L.J.
Rivadeneira, F.
Rudan, I.
Rudolph, A.
Ruggiero, D.
Sala, C.F.
Sanna, S.
Sawyer, E.J.
Schlessinger, D.
Schmidt, M.K.
Schmidt, F.
Schmutzler, R.K.
Schoemaker, M.J.
Scott, R.A.
Seynaeve, C.M.
Simard, J.
Sorice, R.
Southey, M.C.
Stöckl, D.
Strauch, K.
Swerdlow, A.
Taylor, K.D.
Thorsteinsdottir, U.
Toland, A.E.
Tomlinson, I.
Truong, T.
Tryggvadottir, L.
Turner, S.T.
Vozzi, D.
Wang, Q.
Wellons, M.
Willemsen, G.
Wilson, J.F.
Winqvist, R.
Wolffenbuttel, B.B.
Wright, A.F.
Yannoukakos, D.
Zemunik, T.
Zheng, W.
Zygmunt, M.
Bergmann, S.
Boomsma, D.I.
Buring, J.E.
Ferrucci, L.
Montgomery, G.W.
Gudnason, V.
Spector, T.D.
van Duijn, C.M.
Alizadeh, B.Z.
Ciullo, M.
Crisponi, L.
Easton, D.F.
Gasparini, P.P.
Gieger, C.
Harris, T.B.
Hayward, C.
Kardia, S.L.
Kraft, P.
McKnight, B.
Metspalu, A.
Morrison, A.C.
Reiner, A.P.
Ridker, P.M.
Rotter, J.I.
Toniolo, D.
Uitterlinden, A.G.
Ulivi, S.
Völzke, H.
Wareham, N.J.
Weir, D.R.
Yerges-Armstrong, L.M.
Generation, Scotland
Price, A.L.
Stefansson, K.
Visser, J.A.
Ong, K.K.
Chang-Claude, J.
Murabito, J.M.
Perry, J.R.
Murray, A.
Pokaż więcej
Temat :
Adult
Age Factors
Aging/genetics
BRCA1 Protein/genetics
Breast Neoplasms/genetics
DNA Repair
Female
Gene Regulatory Networks/genetics
Genetic Predisposition to Disease/genetics
Genetic Variation
Genome-Wide Association Study/methods
Genomics/methods
Genotype
Humans
Hypothalamus/metabolism
Menopause/genetics
Middle Aged
Models, Genetic
Phenotype
Reproduction/genetics
Signal Transduction/genetics
Źródło :
Nature Genetics, vol. 47, no. 11, pp. 1294-1303
Opis pliku :
application/pdf
Tytuł :
DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.
Autorzy :
Osorio, Ana
Milne, Roger L
Kuchenbaecker, Karoline
Vaclová, Tereza
Pita, Guillermo
Alonso, Rosario
Peterlongo, Paolo
Blanco, Ignacio
de la Hoya, Miguel
Duran, Mercedes
Díez, Orland
Mai, Phuong L
Neuhausen, Susan L
Lejbkowicz, Flavio
Ottini, Laura
Lee, Andrew
Buys, Saundra S
Thomassen, Mads
Zaffaroni, Daniela
Andrulis, Irene
Benitez, Javier
Schmutzler, Rita Katharina
Eccles, Diana
Swe-Brca
Platte, Radka
Hodgson, Shirley
Tischkowitz, Marc
Meindl, Alfons
van Deurzen, Carolien H M
Nathanson, Katherine
Donaldson, Alan
Varon-Mateeva, Raymonda
Teulé, Alex
Walsh, Christine
Poppe, Bruce
Ditsch, Nina
Arver, Brita
Morrison, Patrick
Plendl, Hans Jörg
Sutter, Christian
Rantala, Johanna
Johannsson, Oskar Th
Janavicius, Ramunas
Wappenschmidt, Barbara
Stoppa-Lyonnet, Dominique
Brewster, Wendy
Olswold, Curtis
Ding, Yuan Chun
Rookus, Matti A
Lester, Jenny
John, Esther M
Gehrig, Andrea
Herzog, Josef
Lalloo, Fiona
Kauff, Noah
Whittemore, Alice S
Rau-Murthy, Rohini
Weeman, Kisa
Claes, Kathleen
Rutherford, Thomas
Gómez Garcia, Encarna B
Berger, Andreas
Bonanni, Bernardo
Hebon
Hansen, Thomas V O
Rhiem, Kerstin
Jønson, Lars
Wakeley, Katie
Garber, Judy
Foo, Claire
Toland, Amanda Ewart
Ejlertsen, Bent
Pedersen, Inge Sokilde
Ellis, Steve
van Os, Theo A M
Collée, J Margriet
van der Luijt, Rob B
Lubinski, Jan
Simard, Jacques
Izatt, Louise
Teixeira, Manuel R
Mariette, Frederique
Piedmonte, Marion
Volorio, Sara
Hoogerbrugge, Nicoline
Porteous, Mary
Mazoyer, Sylvie
Wang-Gohrke, Shan
Martínez-Bouzas, Cristina
Viel, Alessandra
Soucy, Penny
Side, Lucy
Olah, Edith
Jaworska-Bieniek, Katarzyna
Maugard, Christine
Vijai, Joseph
Beattie, Mary S
Godwin, Andrew K
Investigators, Kconfab
Geschwantler Kaulich, Daphne
Eeles, Ros
van der Kolk, Lizet
Adlard, Julian
Durda, Katarzyna
Steinemann, Doris
Nevanlinna, Heli
Douglas, Fiona
Lázaro, Conxi
Davidson, Rosemarie
Engel, Christoph
Robson, Mark
Preisler-Adams, Sabine
Healey, Sue
Zhang, Liying
Fink-Retter, Anneliese
Mulligan, Anna Marie
Terry, Mary B
Damiola, Francesca
Tea, Muy-Kheng
Friedman, Eitan
Tucker, Kathy
Couch, Fergus J
Glendon, Gord
Kast, Karin
Pfeiler, Georg
Bojesen, Anders
Sunde, Lone
Ramón Y Cajal, Teresa
Moreno, Leticia Thais
Aittomäki, Kristiina
Shimon, Shani Paluch
Loman, Niklas
Scuvera, Giulietta
de Lange, J L
Rebbeck, Timothy R
Konstantopoulou, Irene
Backes, Floor
Laitman, Yael
Andrés Conejero, Raquel
McGuffog, Lesley
Rodríguez, Gustavo
Radice, Paolo
Devilee, Peter
Chenevix-Trench, Georgia
Olopade, Olufunmilayo I
Daly, Mary B
Evans, Gareth
Menéndez, Mireia
Dorfling, Cecilia M
Meijers-Heijboer, Hanne E J
van der Hout, A H
Ehrencrona, Hans
Montagna, Marco
Phelan, Catherine M
Cook, Jackie
van Asperen, Christi J
Brewer, Carole
Tognazzo, Silvia
Arun, Banu K
Hopper, John
Gerdes, Anne-Marie
Kennedy, John
Guidugli, Lucia
Manoukian, Siranoush
Jakubowska, Anna
Antoniou, Antonis C
Cybulski, Cezary
Southey, Melissa
Singer, Christian F
Easton, Douglas F
Arnold, Norbert
Gronwald, Jacek
Niederacher, Dieter
Rappaport, Christine
van Rensburg, Elizabeth J
Herráez, Belén
Weitzel, Jeffrey N
Varesco, Liliana
Sinilnikova, Olga M
Greene, Mark H
Frost, Debra
Lindor, Noralane
Karlan, Beth Y
Slager, Susan
Infante, Mar
Kruse, Torben A
Domchek, Susan M
Barrowdale, Daniel
Steele, Linda
Szabo, Csilla I
Papi, Laura
Jensen, Uffe Birk
Peissel, Bernard
Tibiletti, Maria Grazia
Yannoukakos, Drakoulis
Cole, Trevor
Caldés, Trinidad
Offit, Kenneth
Fineberg, Elena
Walker, Lisa
Pokaż więcej
Temat :
Brjóstakrabbamein
Arfgengi
Breast Neoplasms/genetics
DNA Glycosylases/genetics
DNA Repair/genetics
Adolescent
Adult
Aged
Aged, 80 and over
BRCA1 Protein/genetics
BRCA2 Protein/genetics
Female
Genetic Predisposition to Disease
Genotype
Humans
Middle Aged
Ovarian Neoplasms/genetics
Polymorphism, Single Nucleotide/genetics
Risk
Tytuł :
Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Autorzy :
Kirchhoff, T
McGuffog, L
Wang, X
Chen, X
Beesley, J
Soucy, P
Kuchenbaecker, KB
Ramus, SJ
Antoniou, AC
Gaudet, MM
Couch, FJ
MeijersHeijboer, HEJ
Chung, WK
John, EM
Miron, A
Southey, MC
Hopper, JL
Goldgar, DE
Singer, CF
Rappaport, C
Tea, MKM
FinkRetter, A
Barrowdale, D
Hansen, TVO
Nielsen, FC
Arason, A
Vijai, J
Shah, S
Sarrel, K
Robson, ME
Piedmonte, M
Phillips, K
Basil, J
Lee, A
Rubinstein, WS
Boggess, J
Wakeley, K
EwartToland, A
Montagna, M
Agata, S
Imyanitov, EN
Isaacs, C
Janavicius, R
Lazaro, C
Healey, S
Blanco, I
Feliubadalo, L
Brunet, J
Gayther, SA
Pharoah, PPD
Odunsi, KO
Karlan, BY
Walsh, CS
Olah, E
Teo, SH
Sinilnikova, OM
Ganz, PA
Beattie, MS
Van Rensburg, EJ
Dorfling, CM
Diez, O
Kwong, A
Schmutzler, RK
Wappenschmidt, B
Engel, C
Meindl, A
Andrulis, IL
Ditsch, N
Arnold, N
Heidemann, S
Niederacher, D
PreislerAdams, S
Gadzicki, D
VaronMateeva, R
Deissler, H
Gehrig, A
Sutter, C
Ozcelik, H
Kast, K
Fiebig, B
Heinritz, W
Caldes, T
De La Hoya, M
Muranen, TA
Nevanlinna, H
Tischkowitz, MD
Spurdle, AB
Neuhausen, SL
Mulligan, AM
Ding, YC
Lindor, NM
Fredericksen, Z
Pankratz, VS
Peterlongo, P
Manoukian, S
Peissel, B
Zaffaroni, D
Barile, M
Bernard, L
Thomassen, M
Viel, A
Giannini, G
Varesco, L
Radice, P
Greene, MH
Mai, PL
Easton, DF
ChenevixTrench, G
Offit, K
Simard, J
Gerdes, AM
Jensen, UB
Skytte, AB
Kruse, TA
Caligo, MA
Von Wachenfeldt, A
BarbanyBustinza, G
Loman, N
Soller, M
Ehrencrona, H
Karlsson, P
Nathanson, K
Rebbeck, TR
Domchek, SM
Jakubowska, A
Lubinski, J
Jaworska, K
Durda, K
Zołwocka, E
Huzarski, T
Byrski, T
Gronwald, J
Cybulski, C
Goŕski, B
Osorio, A
Durań, M
Tejada, MI
Benitez, J
Hamann, U
Hogervorst, FBL
Van Os, TA
Van Leeuwen, FE
Wijnen, J
Blok, MJ
Kets, M
Hooning, MJ
Oldenburg, RA
Ausems, MGEM
Peock, S
Frost, D
Ellis, SD
Platte, R
Fineberg, E
Evans, DG
Jacobs, C
Eeles, RA
Adlard, J
Davidson, R
Eccles, DM
Cole, T
Cook, J
Paterson, J
Brewer, C
Douglas, F
Hodgson, SV
Morrison, PJ
Walker, L
Porteous, ME
Kennedy, MJ
Side, LE
Bove, B
Godwin, AK
StoppaLyonnet, D
FassyColcombet, M
Castera, L
Cornelis, F
Mazoyer, S
Leóne, M
BoutryKryza, N
Bressacde Paillerets, B
Caron, O
Pujol, P
Coupier, I
Delnatte, C
Akloul, L
Lynch, HT
Snyder, CL
Buys, SS
Daly, MB
Terry, M
Pokaż więcej
Temat :
skin and connective tissue diseases
Transcription Factors
BRCA2 Protein
Breast Neoplasms
BRCA2 Protein - genetics
United States
BRCA1 Protein - genetics
endocrine system diseases
Ovarian Neoplasms
Polymorphism, Single Nucleotide
Female
DNA-Binding Proteins
Risk Factors
Aged
Chromosomes, Human, Pair 19 - genetics
Middle Aged
Chromosomes, Human, Pair 19
Prognosis
Article
Genotype
Immunoenzyme Techniques
Breast Neoplasms - epidemiology - genetics - metabolism
Mutation
Ovarian Neoplasms - epidemiology - genetics - metabolism
Receptors, Estrogen
Genome-Wide Association Study
BRCA1 Protein
Genetic Predisposition to Disease
Adult
Humans
Źródło :
Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, Wang, X, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A R, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A-M A, Jensen, U B, Skytte, A-B S, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P W, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Górski, B, Osorio, A, Durán, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, van Os, T A & OCGN 2012, ' Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 4, pp. 645-57 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Cancer Epidemiology Biomarkers & Prevention; Vol 21
Tytuł :
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
Autorzy :
Wijnen, Juul
Antoniou, Antonis C
Kuchenbaecker, Karoline B
Soucy, Penny
Beesley, Jonathan
Chen, Xiaoqing
McGuffog, Lesley
Lee, Andrew
Barrowdale, Daniel
Healey, Sue
Sinilnikova, Olga M
Caligo, Maria A
Loman, Niklas
Harbst, Katja
Lindblom, Annika
Arver, Brita
Rosenquist, Richard
Karlsson, Per
Nathanson, Kate
Domchek, Susan
Rebbeck, Tim
Jakubowska, Anna
Lubinski, Jan
Jaworska, Katarzyna
Durda, Katarzyna
Złowowcka-Perłowska, Elżbieta
Osorio, Ana
Durán, Mercedes
Andrés, Raquel
Benítez, Javier
Hamann, Ute
Hogervorst, Frans B
van Os, Theo A
Verhoef, Senno
Meijers-Heijboer, Hanne EJ
Gómez Garcia, Encarna B
Ligtenberg, Marjolijn J
Kriege, Mieke
Collée, J Margriet
Ausems, Margreet GEM
Oosterwijk, Jan C
Peock, Susan
Frost, Debra
Ellis, Steve D
Platte, Radka
Fineberg, Elena
Evans, D Gareth
Lalloo, Fiona
Jacobs, Chris
Eeles, Ros
Adlard, Julian
Davidson, Rosemarie
Cole, Trevor
Cook, Jackie
Paterson, Joan
Douglas, Fiona
Brewer, Carole
Hodgson, Shirley
Morrison, Patrick J
Walker, Lisa
Rogers, Mark T
Donaldson, Alan
Dorkins, Huw
Godwin, Andrew K
Bove, Betsy
Stoppa-Lyonnet, Dominique
Houdayer, Claude
Buecher, Bruno
de Pauw, Antoine
Mazoyer, Sylvie
Calender, Alain
Léoné, Mélanie
Bressac- de Paillerets, Brigitte
Caron, Olivier
Sobol, Hagay
Frenay, Marc
Prieur, Fabienne
Ferrer, Sandra
Mortemousque, Isabelle
Buys, Saundra
Daly, Mary
Miron, Alexander
Terry, Mary
Hopper, John L
John, Esther M
Southey, Melissa
Goldgar, David
Singer, Christian F
Fink-Retter, Anneliese
Tea, Muy-Kheng
Kaulich, Daphne
Hansen, Thomas VO
Nielsen, Finn C
Barkardottir, Rosa B
Gaudet, Mia
Kirchhoff, Tomas
Joseph, Vijai
Dutra-Clarke, Ana
Offit, Kenneth
Piedmonte, Marion
Kirk, Judy
Cohn, David
Hurteau, Jean
Byron, John
Fiorica, James
Toland, Amanda E
Montagna, Marco
Oliani, Cristina
Imyanitov, Evgeny
Isaacs, Claudine
Tihomirova, Laima
Blanco, Ignacio
Lazaro, Conxi
Teulé, Alex
Valle, J Del
Gayther, Simon A
Odunsi, Kunle
Gross, Jenny
Karlan, Beth Y
Olah, Edith
Teo, Soo-Hwang
Ganz, Patricia A
Beattie, Mary S
Dorfling, Cecelia M
van Rensburg, Elizabeth
Diez, Orland
Kwong, Ava
Schmutzler, Rita K
Wappenschmidt, Barbara
Engel, Christoph
Meindl, Alfons
Ditsch, Nina
Arnold, Norbert
Heidemann, Simone
Niederacher, Dieter
Preisler-Adams, Sabine
Gadzicki, Dorothea
Varon-Mateeva, Raymonda
Deissler, Helmut
Gehrig, Andrea
Sutter, Christian
Kast, Karin
Fiebig, Britta
Schäfer, Dieter
Caldes, Trinidad
de la Hoya, Miguel
Nevanlinna, Heli
Muranen, Taru A
Lespérance, Bernard
Spurdle, Amanda B
Neuhausen, Susan L
Ding, Yuan C
Wang, Xianshu
Fredericksen, Zachary
Pankratz, Vernon S
Lindor, Noralane M
Peterlongo, Paolo
Manoukian, Siranoush
Peissel, Bernard
Zaffaroni, Daniela
Bonanni, Bernardo
Bernard, Loris
Dolcetti, Riccardo
Papi, Laura
Ottini, Laura
Radice, Paolo
Greene, Mark H
Loud, Jennifer T
Andrulis, Irene L
Ozcelik, Hilmi
Mulligan, Anna
Glendon, Gord
Thomassen, Mads
Gerdes, Anne-Marie
Jensen, Uffe B
Skytte, Anne-Bine
Kruse, Torben A
Chenevix-Trench, Georgia
Couch, Fergus J
Simard, Jacques
Easton, Douglas F
Pokaż więcej
Temat :
skin and connective tissue diseases
Chromosomes, Human, Pair 12 - genetics
Hereditary Breast and Ovarian Cancer Syndrome - genetics
BRCA2 Protein - genetics
BRCA1 Protein - genetics
Chromosomes, Human, Pair 9 - genetics
Tytuł :
Ovarian Cancer Susceptibility Alleles and Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
Autorzy :
Ramus, Susan J.
Antoniou, Antonis C.
Kuchenbaecker, Karoline B.
Soucy, Penny
Beesley, Jonathan
Chen, Xiaoqing
McGuffog, Lesley
Sinilnikova, Olga M.
Healey, Sue
Barrowdale, Daniel
Lee, Andrew
Thomassen, Mads
Pokaż więcej
Temat :
Retrospective Studies
Ovarian cancer
BRCA2 Protein
Breast cancer
BRCA2 Protein - genetics
BRCA1 Protein - genetics
Middle Aged
Odds Ratio
Heterozygote
Ovarian Neoplasms - genetics
Article
Càncer de mama
endocrine system diseases
Mutation
Ovarian Neoplasms
Càncer d'ovari
Polymorphism, Single Nucleotide
Cohort Studies
BRCA1 Protein
[SDV]Life Sciences [q-bio]
Genetic Predisposition to Disease
Adult
Female
Humans
Źródło :
Ramus, S J, Antoniou, A C, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, McGuffog, L, Sinilnikova, O M, Healey, S, Barrowdale, D, Lee, A R, Thomassen, M, Gerdes, A-M A, Kruse, T A, Jensen, U B, Skytte, A-B S, Caligo, M A, Liljegren, A, Lindblom, A, Olsson, H, Kristoffersson, U, Stenmark-Askmalm, M, Melin, B, Domchek, S M, Nathanson, K L, Rebbeck, T R, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Złowocka, E, Gronwald, J, Huzarski, T, Byrski, T, Cybulski, C, Toloczko-Grabarek, A, Osorio, A, Benitez, J, Duran, M, Tejada, M-I, Hamann, U, Rookus, M, van Leeuwen, F E, Aalfs, C M, Meijers-Heijboer, H E J, van Asperen, C J, van Roozendaal, K E P, Hoogerbrugge, N, Collée, J M, Hansen, T V O & SWE-BRCA 2012, ' Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers ', Human Mutation, vol. 33, no. 4, pp. 690-702 . https://doi.org/10.1002/humu.22025
Human Mutation, Wiley, 2012, 33, pp.690-702. ⟨10.1002/humu.22025⟩
Opis pliku :
application/pdf
Tytuł :
Molecular phylogenetics of shrews (Mammalia: Soricidae) reveal timing of transcontinental colonizations.
Autorzy :
Dubey, S.
Salamin, N.
Ohdachi, S.D.
Barrière, P.
Vogel, P.
Pokaż więcej
Temat :
Africa
Americas
Animals
Apolipoproteins B/genetics
Asia
BRCA1 Protein/genetics
Cell Nucleus/genetics
Cytochrome b Group/genetics
DNA, Mitochondrial/genetics
Models, Genetic
Molecular Sequence Data
Phylogeny
RNA, Ribosomal, 16S/genetics
Sequence Analysis, DNA
Shrews/classification
Shrews/genetics
Źródło :
Molecular Phylogenetics and Evolution, vol. 44, no. 1, pp. 126-137
Opis pliku :
application/pdf
Tytuł :
High percentage of abnormal findings on TVU needs further discussion
Autorzy :
Mourits, M J E
van der Velde, N M
Arts, H J G
de Bock, G H
Pokaż więcej
Temat :
BRCA1 Protein/genetics
BRCA2 Protein/genetics
CA-125 Antigen/analysis
Female
Genetic Predisposition to Disease/genetics
Humans
Mass Screening/methods
Mutation/genetics
Ovarian Neoplasms/diagnosis
Sensitivity and Specificity
Ultrasonography
Vagina/diagnostic imaging
Źródło :
British Jounal of Cancer, 95(8), 1125 - 1125. Nature Publishing Group
Opis pliku :
application/pdf
Tytuł :
Survival analysis in familial ovarian cancer, a case control study
Autorzy :
Zweemer, R P
Verheijen, R H
Coebergh, J W
Jacobs, I J
van Diest, P J
Gille, J J
Skates, S
Menko, F H
Ten Kate, L P
Kenemans, P
Pokaż więcej
Temat :
BRCA1 Protein/genetics
BRCA2 Protein/genetics
Case-Control Studies
Female
Germ-Line Mutation
Humans
Middle Aged
Ovarian Neoplasms/genetics
Pedigree
Survival Rate
Źródło :
European Journal of Obstetrics and Gynecology and Reproductive Biology, 98(2), 219 - 23. Elsevier Ireland Ltd
Tytuł :
Presymptomatic testing for BRCA1 and BRCA2: how distressing are the pre-test weeks? Rotterdam/Leiden Genetics Working Group
Autorzy :
Lodder, Litanja
Devilee, Peter
Niermeijer, Martinus
Cornelisse, Cees
Frets, P.G.
Trijsburg, Wim
Meijers-Heijboer, Hanne
Klijn, Jan
Duivenvoorden, Hugo
Tibben, Arend
Wagner, Anja
Meer, C.A.
Pokaż więcej
Temat :
Transcription Factors/*genetics
BRCA2 Protein
Aged
Middle aged
BRCA1 Protein/*genetics
Breast Neoplasms/genetics/*psychology
Research Support, Non-U.S. Gov't
Genetic Screening/*psychology
Neoplasm Proteins/*genetics
Adult
Female
Genetic Markers
Humans
Anxiety/psychology
Źródło :
Journal of medical genetics, 36(12), 906 - 913. BMJ Publishing Group
Journal of Medical Genetics
Opis pliku :
application/pdf
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