Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""BRCA2"" wg kryterium: Temat


Tytuł:
Multi-Gene Next-Generation Sequencing Panel for Analysis of BRCA1 / BRCA2 and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer.
Autorzy:
Maloberti T; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
De Leo A; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
Coluccelli S; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Sanza V; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Gruppioni E; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Altimari A; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Zagnoni S; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Giunchi F; Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Vasuri F; Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Fiorentino M; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.; Pathology Unit, Maggiore Hospital, AUSL Bologna, 40133 Bologna, Italy.
Mollica V; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Ferrari S; Unit of Medical Genetics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Miccoli S; Unit of Medical Genetics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Visani M; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.
Turchetti D; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.; Unit of Medical Genetics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Massari F; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Tallini G; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
de Biase D; Solid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.; Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 18; Vol. 24 (10). Date of Electronic Publication: 2023 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, BRCA2*
Prostatic Neoplasms, Castration-Resistant*/pathology
Male ; Humans ; Recombinational DNA Repair/genetics ; Germ-Line Mutation ; Biomarkers, Tumor/genetics ; High-Throughput Nucleotide Sequencing ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics
Czasopismo naukowe
Tytuł:
MARGINAL: An Automatic Classification of Variants in BRCA1 and BRCA2 Genes Using a Machine Learning Model.
Autorzy:
Karalidou V; School of Electrical and Computer Engineering, National Technical University of Athens, 15780 Athens, Greece.
Kalfakakou D; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research NCSR Demokritos, 15341 Athens, Greece.
Papathanasiou A; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research NCSR Demokritos, 15341 Athens, Greece.
Fostira F; Molecular Diagnostics Laboratory, INRaSTES, National Center for Scientific Research NCSR Demokritos, 15341 Athens, Greece.
Matsopoulos GK; School of Electrical and Computer Engineering, National Technical University of Athens, 15780 Athens, Greece.
Pokaż więcej
Źródło:
Biomolecules [Biomolecules] 2022 Oct 24; Vol. 12 (11). Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Genes, BRCA2*
Female ; Humans ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Genetic Predisposition to Disease ; Genetic Testing ; Genetic Variation ; Machine Learning
Czasopismo naukowe
Tytuł:
Central nervous system metastases in breast cancer patients with germline BRCA pathogenic variants compared to non-carriers: a matched-pair analysis.
Autorzy:
Ben-Zion Berliner M; Breast cancer Unit, Davidoff Cancer Center, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel. .
Yust-Katz S; Neuro-Oncology Unit, Davidoff Cancer Center, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Lavie I; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Goldberg Y; The Raphael Recanati Genetics Institute, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Kedar I; The Raphael Recanati Genetics Institute, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.
Yerushalmi R; Breast cancer Unit, Davidoff Cancer Center, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.; Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Pokaż więcej
Źródło:
BMC cancer [BMC Cancer] 2024 Feb 16; Vol. 24 (1), pp. 219. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
BRCA1 Protein*/genetics
BRCA2 Protein*/genetics
Breast Neoplasms*/pathology
Central Nervous System Neoplasms*/genetics
Central Nervous System Neoplasms*/secondary
Female ; Humans ; Central Nervous System ; Germ Cells/pathology ; Germ-Line Mutation ; Matched-Pair Analysis ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Tytuł:
A novel targeted NGS panel identifies numerous homologous recombination deficiency (HRD)-associated gene mutations in addition to known BRCA mutations.
Autorzy:
Vogel A; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, Mainz, 55131, Germany.
Haupts A; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, Mainz, 55131, Germany.
Kloth M; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, Mainz, 55131, Germany.
Roth W; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, Mainz, 55131, Germany.
Hartmann N; Institute of Pathology, University Medical Center Mainz, Langenbeckstraße 1, Mainz, 55131, Germany. .
Pokaż więcej
Źródło:
Diagnostic pathology [Diagn Pathol] 2024 Jan 06; Vol. 19 (1), pp. 9. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
BRCA1 Protein*/genetics
BRCA2 Protein*/genetics
Male ; Humans ; Retrospective Studies ; Mutation ; Homologous Recombination
Czasopismo naukowe
Tytuł:
Pan-cancer analysis of co-occurring mutations in RAD52 and the BRCA1-BRCA2-PALB2 axis in human cancers.
Autorzy:
Hamid AB; Medical College of Wisconsin, Milwaukee, WI, United States of America.
Frank LE; Zoology Undergraduate Program, The Ohio State University, Marion, OH, United States of America.
Bouley RA; Department of Chemistry and Biochemistry, The Ohio State University, Marion, OH, United States of America.
Petreaca RC; Department of Molecular Genetics, The Ohio State University at Marion, Marion, OH, United States of America.; Cancer Biology Program, The Ohio State University James Comprehensive Cancer Center, Columbus, OH, United States of America.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2022 Sep 15; Vol. 17 (9), pp. e0273736. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Genes, BRCA2*
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; DNA ; DNA Repair ; Fanconi Anemia Complementation Group N Protein/genetics ; Female ; Humans ; Mutation ; Rad52 DNA Repair and Recombination Protein/genetics
Czasopismo naukowe
Tytuł:
Screening of BRCA1 (c.5177_5180delGAAA rs80357867 and c.4986+6T>C rs80358086) and the BRCA2 (c.6445_6446delAT rs80359592) Genes for Breast Cancer Prevention in Burkina Faso.
Autorzy:
Kiendrebeogo IT; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Zoure AA; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Institute of Health Sciences Research, Department of Biomedical and Public Health, Burkina Faso.
Zongo FI; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.
Ouedraogo SY; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Sawadogo AY; Service of Gynecology, University Hospital Center Bogodogo, University Joseph KI-ZERBO, UFR/SDS, Burkina Faso.
Amegnona J; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.
Sombie HK; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Bazie JTVE; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Sorgho PA; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Yonli AT; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.
Ouedraogo MNL; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Faculty of Health Sciences, University Saint Thomas d'Aquin.
Obiri-Yeboah D; Department of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast.
Zongo N; Department of General and Digestive Surgery, University Hospital Center Yalgado Ouedraogo, University Joseph KI-ZERBO, UFR/SDS, Burkina Faso.
Bambara HA; Service of oncology, University Hospital Center Bogodogo, University Joseph KI-ZERBO, UFR/SDS, Burkina Faso.
Simpore J; Laboratory of Molecular Biology and Genetics, UFR/SVT, University Joseph KI-ZERBO, Burkina Faso.; Pietro Annigoni Biomolecular Research Center, Burkina Faso.; Faculty of Health Sciences, University Saint Thomas d'Aquin.
Pokaż więcej
Źródło:
Ethiopian journal of health sciences [Ethiop J Health Sci] 2022 Jul; Vol. 32 (4), pp. 699-708.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Genes, BRCA2*
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Burkina Faso ; Case-Control Studies ; Early Detection of Cancer ; Female ; Genes, BRCA1 ; Genetic Predisposition to Disease ; Humans
Czasopismo naukowe
Tytuł:
Immunohistochemical Evaluation of BAP1 Expression in Breast Cancer with Known BRCA1 and BRCA2 Mutations and Comparison with Histopathological Features.
Autorzy:
Çalım-Gürbüz B; Pathology Department, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Güvendir İ; Pathology Department, 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Ünal B; Genomic Laboratory (GLAB), 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Erdoğan-Durmuş Ş; Pathology Department, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Topal CS; Pathology Department, 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Ağaoğlu NB; Genomic Laboratory (GLAB), 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Doğanay HL; Genomic Laboratory (GLAB), 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Kızılboğa T; Genomic Laboratory (GLAB), 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Zemheri IE; Pathology Department, 147021Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Pokaż więcej
Źródło:
International journal of surgical pathology [Int J Surg Pathol] 2022 Jun; Vol. 30 (4), pp. 397-404. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
BRCA1 Protein*/genetics
BRCA2 Protein*/genetics
Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Breast Neoplasms*/pathology
Tumor Suppressor Proteins*/genetics
Ubiquitin Thiolesterase*/genetics
Female ; Genes, BRCA2 ; Humans ; Mutation
Czasopismo naukowe
Tytuł:
Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.
Autorzy:
Aljarf R; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia.; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia.
Shen M; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia.; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia.; School of Computing and Information Systems, University of Melbourne, Melbourne, VIC, 3053, Australia.
Pires DEV; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia. .; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia. .; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia. .; School of Computing and Information Systems, University of Melbourne, Melbourne, VIC, 3053, Australia. .
Ascher DB; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia. .; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia. .; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia. .; Department of Biochemistry, University of Cambridge, 80 Tennis Ct Rd, Cambridge, CB2 1GA, UK. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jun 21; Vol. 12 (1), pp. 10458. Date of Electronic Publication: 2022 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein*/genetics
BRCA2 Protein*/genetics
Breast Neoplasms*/genetics
Mutation, Missense*
Ovarian Neoplasms*/genetics
Female ; Genes, BRCA2 ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans
Czasopismo naukowe
Tytuł:
BRCA1/2 Mutation Types Do Not Affect Prognosis in Ovarian Cancer Patients.
Autorzy:
Liontos M; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Zografos E; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Zoumpourlis P; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Andrikopoulou A; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Svarna A; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Fiste O; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Kunadis E; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Papatheodoridi AM; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Kaparelou M; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Koutsoukos K; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Thomakos N; 1st Department of Obstetrics and Gyencology, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Haidopoulos D; 1st Department of Obstetrics and Gyencology, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Rodolakis A; 1st Department of Obstetrics and Gyencology, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Dimopoulos MA; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Zagouri F; Oncology Unit, Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Pokaż więcej
Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2021 Nov 03; Vol. 28 (6), pp. 4446-4456. Date of Electronic Publication: 2021 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, BRCA1*
Genes, BRCA2*
Ovarian Neoplasms*/diagnosis
Ovarian Neoplasms*/genetics
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Female ; Humans ; Mutation ; Prognosis
Czasopismo naukowe
Tytuł:
Multitumor Case Series of Germline BRCA1 , BRCA2 and CHEK2 -Mutated Patients Responding Favorably on Immune Checkpoint Inhibitors.
Autorzy:
Kinget L; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Bechter O; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Punie K; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Debruyne PR; Department of General Medical Oncology, AZ Groeninge, 8500 Kortrijk, Belgium.; Medical Technology Research Centre (MTRC), School of Life Sciences, Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.
Brems H; Department of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
Clement P; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Roussel E; Department of Urology, University Hospitals Leuven, 3000 Leuven, Belgium.
Van Herck Y; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Albersen M; Department of Urology, University Hospitals Leuven, 3000 Leuven, Belgium.
Baldewijns M; Department of Pathology, University Hospitals Leuven, 3000 Leuven, Belgium.
Schöffski P; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Beuselinck B; Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, 3000 Leuven, Belgium.
Pokaż więcej
Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2021 Aug 24; Vol. 28 (5), pp. 3227-3239. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, BRCA2*
Immune Checkpoint Inhibitors*
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Checkpoint Kinase 2/genetics ; Germ Cells ; Humans
Czasopismo naukowe
Tytuł:
Short-term Impact of Hormone Replacement Therapy on Risk of Breast Cancer in BRCA Mutation Carriers: A Nationwide Study in South Korea.
Autorzy:
Kim HY; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Park J; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Moon SJ; Smart Healthcare Center, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Jeong S; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Hong JH; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Lee JK; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Cho GJ; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.; Smart Healthcare Center, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Cho HW; Department of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Pokaż więcej
Źródło:
Cancer research and treatment [Cancer Res Treat] 2024 Jan; Vol. 56 (1), pp. 143-148. Date of Electronic Publication: 2023 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/etiology
Breast Neoplasms*/genetics
Ovarian Neoplasms*/genetics
Female ; Humans ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Genes, BRCA2 ; Genes, BRCA1 ; Hormone Replacement Therapy/adverse effects ; Mutation
Czasopismo naukowe
Tytuł:
Germline mutations of homologous recombination genes and clinical outcomes in pancreatic cancer: a multicenter study in Taiwan.
Autorzy:
Cheng SM; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Su YY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Deparment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chiang NJ; Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wang CJ; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Surgery, National Cheng-Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chao YJ; Department of Surgery, National Cheng-Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Huang CJ; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Tsai HJ; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Deparment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen SH; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.; Deparment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chang CY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Tsai CR; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Li YJ; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Yen CJ; Deparment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chuang SC; Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Surgery, Faculty of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chang JS; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
Shan YS; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. .; Department of Surgery, National Cheng-Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. .
Hwang DY; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan. .; Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Center for Biomarkers and Biotech Drugs, Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan. .; Precision Medicine Ph.D. Program, National Tsing Hua University, Hsinchu, Taiwan. .
Chen LT; National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan. .; Deparment of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. .; Department of Internal Medicine, Kaohsiung Medical University Hospital and Center for Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan. .
Pokaż więcej
Źródło:
Journal of biomedical science [J Biomed Sci] 2024 Feb 13; Vol. 31 (1), pp. 21. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Germ-Line Mutation*
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Humans ; Taiwan ; Homologous Recombination ; Genes, BRCA2 ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics
Czasopismo naukowe
Tytuł:
BRCA1/2 Serves as a Biomarker for Poor Prognosis in Breast Carcinoma.
Autorzy:
Jin TY; Department of Surgery, Konkuk University School of Medicine, Seoul 05030, Korea.; Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.
Park KS; Department of Surgery, Konkuk University School of Medicine, Seoul 05030, Korea.; Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.; Department of Surgery, Konkuk University Medical Center, Seoul 05030, Korea.
Nam SE; Department of Surgery, Konkuk University School of Medicine, Seoul 05030, Korea.; Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.; Department of Surgery, Konkuk University Medical Center, Seoul 05030, Korea.
Yoo YB; Department of Surgery, Konkuk University School of Medicine, Seoul 05030, Korea.; Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.; Department of Surgery, Konkuk University Medical Center, Seoul 05030, Korea.
Park WS; Department of Surgery, Kyung Hee University School of Medicine, Seoul 02447, Korea.
Yun IJ; Department of Surgery, Konkuk University School of Medicine, Seoul 05030, Korea.; Research Institute of Medical Science, Konkuk University School of Medicine, Seoul 05030, Korea.; Department of Surgery, Konkuk University Medical Center, Seoul 05030, Korea.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 29; Vol. 23 (7). Date of Electronic Publication: 2022 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/metabolism
Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
BRCA2 Protein/*genetics
BRCA1 Protein/genetics ; BRCA1 Protein/metabolism ; Breast/pathology ; Female ; Genes, BRCA2 ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Remarkable response to pazopanib plus vivolumab in a patient with pericardial synovial sarcoma carrying a novel genotype BRCA2 c.968dupT: A case report.
Autorzy:
Zhang X; Graduate Collaborative Training Base of Hunan Cancer Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.; Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital, Department of Medical Oncology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, China.
Xu Q; Department of Medical Oncology, Qinghai Provincial People's Hospital, Xining, Qinghai, China.
Zhang Y; Graduate Collaborative Training Base of Hunan Cancer Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, China.; Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital, Department of Medical Oncology, The Affiliated Cancer Hospital of Xiangya School of Medicine, Changsha, Hunan, China.
Pokaż więcej
Źródło:
Thoracic cancer [Thorac Cancer] 2024 Mar; Vol. 15 (8), pp. 667-671. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Case Reports
MeSH Terms:
Sarcoma, Synovial*/drug therapy
Sarcoma, Synovial*/genetics
Mediastinal Neoplasms*/drug therapy
Thymus Neoplasms*/drug therapy
Heart Neoplasms*/drug therapy
Pleural Neoplasms*/drug therapy
Indazoles*
Humans ; Adolescent ; Nivolumab/pharmacology ; Nivolumab/therapeutic use ; Pyrimidines/therapeutic use ; Sulfonamides/pharmacology ; Sulfonamides/therapeutic use ; BRCA2 Protein/genetics
Raport
Tytuł:
Complexity of the Genetic Background of Oncogenesis in Ovarian Cancer-Genetic Instability and Clinical Implications.
Autorzy:
Murawski M; 1st Clinical Department of Gynecology and Obstetrics, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Jagodziński A; 1st Clinical Department of Gynecology and Obstetrics, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Bielawska-Pohl A; Laboratory of Biology of Stem and Neoplastic Cells, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Klimczak A; Laboratory of Biology of Stem and Neoplastic Cells, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Pokaż więcej
Źródło:
Cells [Cells] 2024 Feb 15; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Cystadenocarcinoma, Serous*/genetics
Female ; Humans ; BRCA1 Protein/genetics ; Tumor Suppressor Protein p53/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; BRCA2 Protein/genetics ; Carcinogenesis ; Cell Transformation, Neoplastic ; Class I Phosphatidylinositol 3-Kinases/genetics ; Genetic Background
Czasopismo naukowe
Tytuł:
BRCA1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancer.
Autorzy:
Richau CS; Tumoral Genetics and Virology Program, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Scherer NM; Bioinformatics and Computational Biology Laboratory, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Matta BP; Tumoral Genetics and Virology Program, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
de Armas EM; Bioinformatics and Computational Biology Laboratory, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
de Barros Moreira FC; Division of Pathology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Bergmann A; Clinical Epidemiology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Pereira Chaves CB; Gynecologic Oncology Department, Cancer Hospital II, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Boroni M; Bioinformatics and Computational Biology Laboratory, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Dos Santos ACE; Tumoral Genetics and Virology Program, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Moreira MAM; Tumoral Genetics and Virology Program, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Pokaż więcej
Źródło:
Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (3), pp. e6729. Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Ovarian Neoplasms*/genetics
Humans ; Female ; Carcinoma, Ovarian Epithelial/genetics ; Brazil/epidemiology ; DNA Repair ; Germ Cells ; Tumor Suppressor Protein p53/genetics ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics
Czasopismo naukowe
Tytuł:
BRCA 1/2 mutations and risk of uterine cancer: a systematic review and meta-analysis.
Autorzy:
Zakerinasab F; Mashhad University of Medical Sciences, Mashhad, Iran.
Behfar Q; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Parsaee R; Master Student in Molecular Genetics, Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Zadeh RH; Student's Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Foroughi E; School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Amirbeik A; Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmadi G; Mashhad University of Medical Sciences, Mashhad, Iran. Ghazale_.
Pokaż więcej
Źródło:
BMC genomic data [BMC Genom Data] 2024 Jan 31; Vol. 25 (1), pp. 13. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
BRCA1 Protein*/genetics
Uterine Neoplasms*/epidemiology
Uterine Neoplasms*/genetics
Uterine Neoplasms*/prevention & control
Humans ; Female ; BRCA2 Protein/genetics ; Mutation ; Cross-Sectional Studies
Czasopismo naukowe
Tytuł:
Counselling Framework for Germline BRCA1/2 and PALB2 Carriers Considering Risk-Reducing Mastectomy.
Autorzy:
Wong SM; Department of Surgery, McGill University, Montreal, QC H3G 1A4, Canada.; Stroll Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H4A 3T2, Canada.
Apostolova C; Department of Surgery, McGill University, Montreal, QC H3G 1A4, Canada.; Stroll Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
Eisenberg E; Department of Surgery, McGill University, Montreal, QC H3G 1A4, Canada.; Stroll Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC H3T 1E2, Canada.
Foulkes WD; Stroll Cancer Prevention Centre, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC H3T 1E2, Canada.; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H4A 3T2, Canada.; Department of Human Genetics, McGill University, Montreal, QC H3A 0C7, Canada.
Pokaż więcej
Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2024 Jan 09; Vol. 31 (1), pp. 350-365. Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mastectomy*
Breast Neoplasms*/genetics
Breast Neoplasms*/surgery
Pregnancy ; Humans ; Female ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Counseling ; Germ Cells ; Fanconi Anemia Complementation Group N Protein/genetics
Czasopismo naukowe
Tytuł:
BRCA1 and BRCA2 germline mutations in Chinese Hakka breast cancer patients.
Autorzy:
Zhang Y; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Engineering Technological Research Center of Clinical Molecular Diagnosis and Antibody Drugs, Meizhou, China.
Wu H; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.
Gan C; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.; Guangdong Engineering Technological Research Center of Clinical Molecular Diagnosis and Antibody Drugs, Meizhou, China.
Rao H; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China.
Wang Q; Department of Medical Oncology, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou, People's Republic of China.
Guo X; Center for Precision Medicine, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, No 63 Huangtang Road, Meijiang District, Meizhou, 514031, P. R. China. .; Guangdong Engineering Technological Research Center of Clinical Molecular Diagnosis and Antibody Drugs, Meizhou, China. .
Pokaż więcej
Źródło:
BMC medical genomics [BMC Med Genomics] 2024 Jan 02; Vol. 17 (1), pp. 3. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Female ; Humans ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; China/epidemiology ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Ki-67 Antigen/genetics
Czasopismo naukowe
Tytuł:
BRACNAC: A BRCA1 and BRCA2 Copy Number Alteration Caller from Next-Generation Sequencing Data.
Autorzy:
Kechin A; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.; Faculty of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia.
Boyarskikh U; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Borobova V; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.; Faculty of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia.
Khrapov E; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Subbotin S; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Filipenko M; Institute of Chemical Biology and Fundamental Medicine, Novosibirsk 630090, Russia.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 22; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Copy Number Variations*
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/diagnosis
Prostatic Neoplasms*/genetics
Female ; Humans ; Male ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Genes, BRCA2 ; High-Throughput Nucleotide Sequencing/methods
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies