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Tytuł:
Small-scale mutations are infrequent as mechanisms of resistance in post-PARP inhibitor tumour samples in high grade serous ovarian cancer.
Autorzy:
Burdett NL; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, 3010, Australia.; Box Hill Hospital, Eastern Health, Box Hill, Victoria, 3128, Australia.
Willis MO; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Pandey A; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Fereday S; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
DeFazio A; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, 2145, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, 2006, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, 2145, Australia.
Bowtell DDL; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, 3010, Australia.
Christie EL; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia. .; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, 3010, Australia. .
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Corporate Authors:
AOCS Study Group
Źródło:
Scientific reports [Sci Rep] 2023 Dec 11; Vol. 13 (1), pp. 21884. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/therapeutic use
Ovarian Neoplasms*/drug therapy
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/pathology
Humans ; Female ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Mutation ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Globally shared TCR repertoires within the tumor-infiltrating lymphocytes of patients with metastatic gynecologic cancer.
Autorzy:
Kim T; Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Lim H; Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Jun S; Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Park J; Department of Obstetrics and Gynecology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Lee D; Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Lee JH; Department of Clinical Pharmacology and Therapeutics, College of Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.; Department of Biomedical Science and Technology, Kyung Hee Medical Science Research Institute, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.
Lee JY; Department of Obstetrics and Gynecology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea. .
Bang D; Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 22; Vol. 13 (1), pp. 20485. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Ovarian Neoplasms*/genetics
Endometrial Neoplasms*/genetics
Humans ; Female ; BRCA1 Protein ; Lymphocytes, Tumor-Infiltrating ; BRCA2 Protein ; Receptors, Antigen, T-Cell/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.
Autorzy:
Aljarf R; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia.; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia.
Shen M; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia.; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia.; School of Computing and Information Systems, University of Melbourne, Melbourne, VIC, 3053, Australia.
Pires DEV; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia. .; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia. .; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia. .; School of Computing and Information Systems, University of Melbourne, Melbourne, VIC, 3053, Australia. .
Ascher DB; Computational Biology and Clinical Informatics, Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia. .; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, VIC, 3010, Australia. .; Systems and Computational Biology, Bio21 Institute, University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3052, Australia. .; Department of Biochemistry, University of Cambridge, 80 Tennis Ct Rd, Cambridge, CB2 1GA, UK. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 21; Vol. 12 (1), pp. 10458. Date of Electronic Publication: 2022 Jun 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein*/genetics
BRCA2 Protein*/genetics
Breast Neoplasms*/genetics
Mutation, Missense*
Ovarian Neoplasms*/genetics
Female ; Genes, BRCA2 ; Genetic Predisposition to Disease ; High-Throughput Nucleotide Sequencing ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines.
Autorzy:
Witz A; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France. .; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France. .
Dardare J; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
Francois A; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.; Département Recherche, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
Husson M; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
Rouyer M; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
Demange J; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
Merlin JL; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
Gilson P; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
Harlé A; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 31; Vol. 13 (1), pp. 18741. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma*/genetics
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/pathology
Humans ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; CRISPR-Cas Systems ; Phthalazines/pharmacology ; Germ-Line Mutation ; Mutation ; MCF-7 Cells ; Pancreatic Neoplasms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical and biomarker factors affecting survival in patients with platinum-sensitive relapsed ovarian cancer receiving olaparib monotherapy: a multicenter retrospective study.
Autorzy:
Tashiro R; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.; Division of Pharmaceutical Care Sciences, Keio University Graduate School of Pharmaceutical Sciences, Tokyo, Japan.
Kawazoe H; Division of Pharmaceutical Care Sciences, Keio University Graduate School of Pharmaceutical Sciences, Tokyo, Japan. .; Division of Pharmaceutical Care Sciences, Center for Social Pharmacy and Pharmaceutical Care Sciences, Faculty of Pharmacy, Keio University, Tokyo, Japan. .
Mamishin K; Department of Pharmacy, National Cancer Center Hospital East, Chiba, Japan.
Seto K; Department of Pharmacy, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Udagawa R; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.
Saito Y; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.
Hashimoto H; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.
Shimoi T; Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yonemori K; Department of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yonemura M; Department of Pharmacy, National Cancer Center Hospital East, Chiba, Japan.
Terakado H; Department of Pharmacy, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Nishimura T; Department of Pharmacy, Center Hospital of the National Center for Global Health and Medicine, Tokyo, Japan.
Kawasaki T; Department of Pharmacy, National Cancer Center Hospital East, Chiba, Japan.
Furukawa T; Department of Pharmacy, National Cancer Center Hospital, Tokyo, Japan.
Nakamura T; Division of Pharmaceutical Care Sciences, Keio University Graduate School of Pharmaceutical Sciences, Tokyo, Japan.; Division of Pharmaceutical Care Sciences, Center for Social Pharmacy and Pharmaceutical Care Sciences, Faculty of Pharmacy, Keio University, Tokyo, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 24; Vol. 13 (1), pp. 11962. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
BRCA1 Protein*
Ovarian Neoplasms*
Female ; Humans ; BRCA2 Protein ; Prospective Studies ; Retrospective Studies ; CA-125 Antigen ; Carcinoma, Ovarian Epithelial ; Platinum
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types.
Autorzy:
Shi Z; Department of Translational Medicine Center, Chigene (Beijing) Translational Medical Research Center Co., Beijing, 100176, China.; Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation, Shanghai Institute of Planned Parenthood Research, State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Reproduction and Development, Fudan University, Shanghai, 200032, China.
Chen B; Department of Thoracic Medical Oncology，Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000, China.
Han X; Obstetrics and Gynecology Hospital, NHC Key Laboratory of Reproduction Regulation, Shanghai Institute of Planned Parenthood Research, State Key Laboratory of Genetic Engineering at School of Life Sciences, Institute of Reproduction and Development, Fudan University, Shanghai, 200032, China.
Gu W; Department of Translational Medicine Center, Chigene (Beijing) Translational Medical Research Center Co., Beijing, 100176, China.
Liang S; Department of Thoracic Medical Oncology，Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000, China.
Wu L; Department of Thoracic Medical Oncology，Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410000, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 01; Vol. 13 (1), pp. 8899. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein*/genetics
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/drug therapy
Female ; Humans ; BRCA2 Protein/genetics ; Homologous Recombination/genetics ; Genomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prevalence of BRCA homopolymeric indels in an ION Torrent-based tumour-to-germline testing workflow in high-grade ovarian carcinoma.
Autorzy:
Azzollini J; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Agnelli L; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.; Medical Oncology 1 Department, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Conca E; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Torelli T; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.; Medical Oncology 1 Department, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Busico A; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Capone I; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Angelini M; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Tamborini E; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Perrone F; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Vingiani A; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.; Oncology and Hemato-Oncology Department, University of Milan, Milan, Italy.
Lorenzini D; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Peissel B; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.
Pruneri G; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy.; Oncology and Hemato-Oncology Department, University of Milan, Milan, Italy.
Manoukian S; Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, via Venezian 1, 20133, Milan, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 13; Vol. 13 (1), pp. 7781. Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein*/genetics
Ovarian Neoplasms*/epidemiology
Ovarian Neoplasms*/genetics
Female ; Humans ; BRCA2 Protein/genetics ; Retrospective Studies ; Prevalence ; Workflow ; Carcinoma, Ovarian Epithelial ; Germ-Line Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preoperative diagnosis of BRCA1/2 mutation impacts decision-making for risk-reducing mastectomy in breast cancer patients.
Autorzy:
Woo J; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Gwak G; Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South Korea.
Park I; Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South Korea.
Bae BN; Department of Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South Korea.
Lee SK; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Chae BJ; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Yu J; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Lee JE; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Kim SW; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Nam SJ; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Ryu JM; Division of Breast Surgery, Department of Surgery, Samsung Medical Center Cancer Hospital, Sungkyunkwan University School of Medicine, 5th Floor Breast-Endocrine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 20; Vol. 11 (1), pp. 14747. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Decision Making*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Breast Neoplasms/*diagnosis
Adult ; Aged ; BRCA1 Protein/metabolism ; BRCA2 Protein/metabolism ; Breast Neoplasms/surgery ; Female ; Humans ; Mastectomy ; Middle Aged ; Mutation ; Odds Ratio ; Preoperative Care ; Retrospective Studies ; Risk Reduction Behavior ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains.
Autorzy:
Kim K; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Kirby TW; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
Perera L; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA.
London RE; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, 27709, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 27; Vol. 11 (1), pp. 9046. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein/*metabolism
BRCA2 Protein/*metabolism
Carrier Proteins/*metabolism
Cell Cycle Proteins/*metabolism
DNA-Binding Proteins/*metabolism
Endodeoxyribonucleases/*metabolism
Nuclear Proteins/*metabolism
Phosphopeptides/*metabolism
X-ray Repair Cross Complementing Protein 1/*metabolism
BRCA1 Protein/chemistry ; BRCA2 Protein/chemistry ; Carrier Proteins/chemistry ; Cell Cycle Proteins/chemistry ; DNA-Binding Proteins/chemistry ; Endodeoxyribonucleases/chemistry ; Humans ; Models, Molecular ; Nuclear Proteins/chemistry ; Phosphopeptides/chemistry ; Phosphorylation ; Protein Binding ; Protein Conformation ; X-ray Repair Cross Complementing Protein 1/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Retarding breast tumor growth with nanoparticle-facilitated intravenous delivery of BRCA1 and BRCA2 tumor suppressor genes.
Autorzy:
Ibnat N; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia.; Department of Bioengineering, George Mason University, Fairfax, VA, 20110, USA.
Chowdhury EH; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor, Malaysia. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 11; Vol. 13 (1), pp. 536. Date of Electronic Publication: 2023 Jan 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/therapy
Mammary Neoplasms, Animal*/genetics
Mammary Neoplasms, Animal*/therapy
Nanoparticles*/therapeutic use
Genetic Therapy*/methods
Animals ; Female ; Humans ; Mice ; BRCA1 Protein/genetics ; BRCA1 Protein/metabolism ; BRCA1 Protein/therapeutic use ; BRCA2 Protein/genetics ; BRCA2 Protein/metabolism ; BRCA2 Protein/therapeutic use ; Cell Line, Tumor ; Genes, BRCA1 ; Genes, BRCA2 ; MCF-7 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of the coverage of risk-reducing salpingo-oophorectomy by the national insurance system for women with BRCA pathogenic variants in Japan.
Autorzy:
Nomura H; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan. .
Abe A; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Fusegi A; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Yoshimitsu T; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Misaka S; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Murakami A; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Matsumoto T; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Tsumura S; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Kanno M; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Aoki Y; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Netsu S; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Omi M; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Tanigawa T; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Okamoto S; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Omatsu K; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Yunokawa M; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Kanao H; Department of Gynecology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Ariake 3-8-31, Koto-Ku, Tokyo, 135-8550, Japan.
Habano E; Department of Clinical Genetics, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Arakawa H; Department of Clinical Genetics, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Kaneko K; Department of Clinical Genetics, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Ueki A; Department of Clinical Genetics, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Haruyama Y; Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Inari H; Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Ueno T; Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 19; Vol. 13 (1), pp. 1018. Date of Electronic Publication: 2023 Jan 19.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Breast Neoplasms*/surgery
Breast Neoplasms*/pathology
Ovarian Neoplasms*/genetics
Ovarian Neoplasms*/prevention & control
Ovarian Neoplasms*/surgery
Humans ; Female ; Salpingo-oophorectomy ; Mastectomy ; Ovariectomy ; Japan ; Mutation ; Genetic Predisposition to Disease ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oncologist-led BRCA 'mainstreaming' in the ovarian cancer clinic: A study of 255 patients and its impact on their management.
Autorzy:
Rumford M; National Heart and Lung Institute, Faculty of Medicine, Imperial College, London, UK. .
Lythgoe M; Department of Medical Oncology, Hammersmith Hospital, London, UK.
McNeish I; Department of Surgery and Cancer, Imperial College, London, UK.
Gabra H; Department of Surgery and Cancer, Imperial College, London, UK.
Tookman L; Department of Medical Oncology, Hammersmith Hospital, London, UK.
Rahman N; Cancer Genetics Unit, Royal Marsden National Health Service Foundation Trust, London, United Kingdom.; Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom.
George A; Gynaecology Unit, The Royal Marsden NHS Foundation Trust, London, UK.
Krell J; Department of Surgery and Cancer, Imperial College, London, UK.
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Źródło:
Scientific reports [Sci Rep] 2020 Feb 25; Vol. 10 (1), pp. 3390. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Ovarian Neoplasms/*drug therapy
Poly(ADP-ribose) Polymerase Inhibitors/*therapeutic use
Adult ; Aged ; Aged, 80 and over ; BRCA1 Protein/metabolism ; BRCA2 Protein/metabolism ; Decision Making ; Female ; Germ-Line Mutation ; Humans ; Middle Aged ; Ovarian Neoplasms/diagnosis ; Platinum/therapeutic use ; Prognosis ; United Kingdom
Czasopismo naukowe
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Tytuł:
Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma.
Autorzy:
Takaya H; Kindai University Faculty of Medicine, Department of Obstetrics and Gynecology, Osakasayama, 589-8511, Japan.
Nakai H; Kindai University Faculty of Medicine, Department of Obstetrics and Gynecology, Osakasayama, 589-8511, Japan.
Takamatsu S; Kyoto University Graduate School of Medicine, Department of Gynecology and Obstetrics, Kyoto, 606-8507, Japan.
Mandai M; Kyoto University Graduate School of Medicine, Department of Gynecology and Obstetrics, Kyoto, 606-8507, Japan.
Matsumura N; Kindai University Faculty of Medicine, Department of Obstetrics and Gynecology, Osakasayama, 589-8511, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2020 Feb 17; Vol. 10 (1), pp. 2757. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Recombinational DNA Repair*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Cystadenocarcinoma, Serous/*diagnosis
DNA, Neoplasm/*genetics
Ovarian Neoplasms/*diagnosis
Allelic Imbalance ; Atlases as Topic ; BRCA1 Protein/metabolism ; BRCA2 Protein/metabolism ; Cystadenocarcinoma, Serous/genetics ; Cystadenocarcinoma, Serous/mortality ; Cystadenocarcinoma, Serous/surgery ; DNA, Neoplasm/metabolism ; Epigenesis, Genetic ; Female ; Humans ; Loss of Heterozygosity ; Middle Aged ; Mutation ; Neoplasm Grading ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/mortality ; Ovarian Neoplasms/surgery ; Precision Medicine ; Prognosis ; Survival Analysis ; Terminology as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Overexpression and alternative splicing of NF-YA in breast cancer.
Autorzy:
Dolfini D; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.
Andrioletti V; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy.; Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076, Tübingen, Germany.
Mantovani R; Dipartimento di Bioscienze, Università degli Studi di Milano, Via Celoria 26, 20133, Milano, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2019 Sep 10; Vol. 9 (1), pp. 12955. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
BRCA1 Protein/*metabolism
BRCA2 Protein/*metabolism
Biomarkers, Tumor/*genetics
Breast Neoplasms/*pathology
CCAAT-Binding Factor/*genetics
E2F Transcription Factors/*metabolism
BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; CCAAT-Binding Factor/metabolism ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; E2F Transcription Factors/genetics ; Female ; Gene Expression Profiling ; Humans ; Promoter Regions, Genetic ; Protein Binding ; Tumor Cells, Cultured
Czasopismo naukowe
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Tytuł:
Physical activity and sleep behaviour in women carrying BRCA1/2 mutations.
Autorzy:
Galasso L; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.
Castelli L; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.
Roveda E; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.; IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy.
Oliverio A; Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. Venezian 1, 20133, Milan, Italy.
Baldassari I; Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. Venezian 1, 20133, Milan, Italy.
Esposito F; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.; IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy.
Mulè A; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.
Montaruli A; Department of Biomedical Sciences for Health, University of Milan, Via G. Colombo 71, 20133, Milan, Italy.; IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy.
Pasanisi P; Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. Venezian 1, 20133, Milan, Italy. .
Bruno E; Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. Venezian 1, 20133, Milan, Italy.
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 27; Vol. 12 (1), pp. 12873. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Exercise*
Sleep Wake Disorders*/epidemiology
BRCA2 Protein/*genetics
BRCA1 Protein/genetics ; Cross-Sectional Studies ; Female ; Heterozygote ; Humans ; Mutation ; Sleep
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Post-Synaptic Function of Brca2.
Autorzy:
Wang CX; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA, 19102, USA.; MD/PhD Program, Drexel University College of Medicine, Philadelphia, PA, 19102, USA.; Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, 77030, USA.
Jimenez-Sainz J; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, 06520, USA.
Jensen RB; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, 06520, USA.
Mazin AV; Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, PA, 19102, USA. .
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Źródło:
Scientific reports [Sci Rep] 2019 Mar 14; Vol. 9 (1), pp. 4554. Date of Electronic Publication: 2019 Mar 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Breaks, Double-Stranded*
DNA Repair*
Homologous Recombination*
BRCA2 Protein/*metabolism
DNA/*metabolism
Rad51 Recombinase/*metabolism
BRCA2 Protein/chemistry ; DNA/chemistry ; Humans ; Nucleic Acid Conformation ; Rad51 Recombinase/chemistry
Czasopismo naukowe
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Tytuł:
Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1).
Autorzy:
Berling-Ernst A; Department of Prevention and Sports Medicine, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany. .
Yahiaoui-Doktor M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
Kiechle M; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Engel C; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
Lammert J; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Grill S; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Dukatz R; Department of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Rhiem K; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University Hospital Cologne, Cologne, Nordrhein-Westfalen, Germany.
Baumann FT; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University Hospital Cologne, Cologne, Nordrhein-Westfalen, Germany.
Bischoff SC; Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
Erickson N; Comprehensive Cancer Center Ludwig Maximillian University (CCC LMU), University of Munich Clinic, Campus Großhadern, Munich, Germany.
Schmidt T; University Cancer Center Schleswig-Holstein (UCCSH), Kiel, Germany.
Niederberger U; Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig Holstein, Kiel, Germany.
Siniatchkin M; Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig Holstein, Kiel, Germany.
Halle M; Department of Prevention and Sports Medicine, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.; DZHK (German Centre for Cardiovascular Research), Munich, Germany.
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2907. Date of Electronic Publication: 2022 Feb 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Attitude to Health*
Exercise Test*
Germ-Line Mutation*
Oxygen Consumption*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
Breast Neoplasms/*prevention & control
Exercise/*psychology
Adult ; Breast Neoplasms/etiology ; Breast Neoplasms/psychology ; Cross-Sectional Studies ; Female ; Heterozygote ; Humans ; Middle Aged ; Prospective Studies ; Surveys and Questionnaires
Czasopismo naukowe
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Tytuł:
Feasibility of targeted cascade genetic testing in the family members of BRCA1/2 gene pathogenic variant/likely pathogenic variant carriers.
Autorzy:
Lee J; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Ham JY; Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Park HY; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Jung JH; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Kim WW; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Kang B; Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Chae YS; Department of Hemato/Oncology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Lee SJ; Department of Hemato/Oncology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Lee IH; Department of Hemato/Oncology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Lee NY; Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. .; Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 03; Vol. 12 (1), pp. 1842. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Carrier Screening*
Genetic Variation*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
Breast Neoplasms/pathology ; Feasibility Studies ; Female ; Genetic Predisposition to Disease ; Heredity ; Heterozygote ; Humans ; Male ; Pedigree ; Phenotype ; Predictive Value of Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Germline sequence variants contributing to cancer susceptibility in South African breast cancer patients of African ancestry.
Autorzy:
Eygelaar D; Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, 0001, South Africa.; Centre for Bioinformatics and Computational Biology, University of Pretoria, Pretoria, 0001, South Africa.; Genomics Research Institute, University of Pretoria, Pretoria, 0001, South Africa.
van Rensburg EJ; Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, 0001, South Africa.; Genomics Research Institute, University of Pretoria, Pretoria, 0001, South Africa.; Genetics Division, University of Pretoria, Pretoria, 0001, South Africa.
Joubert F; Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, 0001, South Africa. .; Centre for Bioinformatics and Computational Biology, University of Pretoria, Pretoria, 0001, South Africa. .; Genomics Research Institute, University of Pretoria, Pretoria, 0001, South Africa. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 17; Vol. 12 (1), pp. 802. Date of Electronic Publication: 2022 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Association Studies*
Breast Neoplasms/*genetics
Genetic Predisposition to Disease/*genetics
Germ-Line Mutation/*genetics
Adult ; Age Distribution ; BRCA2 Protein/genetics ; Black People/genetics ; Cohort Studies ; Female ; Humans ; Middle Aged ; Risk ; South Africa ; Ubiquitin-Protein Ligases/genetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
COVID-19 experiences predicting high anxiety and depression among a sample of BRCA1/BRCA2-positive women in the US.
Autorzy:
Dibble KE; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA. .
Connor AE; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.; Department of Oncology, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, 21205, USA.
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 30; Vol. 11 (1), pp. 24501. Date of Electronic Publication: 2021 Dec 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/epidemiology
Breast Neoplasms*/psychology
COVID-19*/epidemiology
COVID-19*/psychology
Pandemics*
Anxiety ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Cross-Sectional Studies ; Depression ; Female ; Humans ; Middle Aged ; Risk Factors ; Self Report ; United States/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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