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Tytuł:
Preclinical Characterization of the Lu-Labeled Prostate Stem Cell Antigen (PSCA)-Specific Monoclonal Antibody 7F5.
Autorzy:
Striese F; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technical University Dresden, 01062 Dresden, Germany.
Neuber C; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Gräßel S; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technical University Dresden, 01062 Dresden, Germany.
Arndt C; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Ullrich M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Steinbach J; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technical University Dresden, 01062 Dresden, Germany.
Pietzsch J; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; School of Science, Faculty of Chemistry and Food Chemistry, Technical University Dresden, 01062 Dresden, Germany.
Bergmann R; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; Institute of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
Pietzsch HJ; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Sihver W; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Frenz M; Faculty of Informatik and Wirtschaftsinformatik, Provadis School of International Management and Technology AG, 65926 Frankfurt, Germany.
Feldmann A; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Bachmann MP; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; National Center for Tumor Diseases (UCC/NCT), Partner Site Dresden, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 29; Vol. 24 (11). Date of Electronic Publication: 2023 May 29.
Typ publikacji:
Journal Article
MeSH Terms:
Pentetic Acid*/chemistry
Carcinoma*/drug therapy
Animals ; Mice ; Male ; Tissue Distribution ; Prostate ; Cell Line, Tumor ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal/chemistry ; Stem Cells ; Lutetium/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Combining Radiation- with Immunotherapy in Prostate Cancer: Influence of Radiation on T Cells.
Autorzy:
Lindner D; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; Tumor Immunology, University Hospital Carl Gustav Carus, University Cancer Center (UCC), Technical University Dresden, 01307 Dresden, Germany.
Arndt C; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Loureiro LR; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Feldmann A; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Kegler A; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Koristka S; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Berndt N; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Mitwasi N; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.
Bergmann R; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; Institute of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
Frenz M; Faculty Informatik and Wirtschaftsinformatik, Provadis School of International Management and Technology AG, 65926 Frankfurt, Germany.
Bachmann MP; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 18; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Bispecific*
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/radiotherapy
Humans ; Immunologic Factors ; Immunotherapy/methods ; Male ; T-Lymphocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma.
Autorzy:
Plesca I; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Benešová I; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Beer C; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Sommer U; Institute of Pathology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Müller L; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Wehner R; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Heiduk M; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Aust D; Institute of Pathology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Baretton G; Institute of Pathology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Bachmann MP; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Tumor Immunology, University Cancer Center (UCC), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz Center Dresden-Rossendorf, Bautzener Straße 400, 01328 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz Center Dresden-Rossendorf, Bautzener Straße 400, 01328 Dresden, Germany.
Weitz J; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Seifert L; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Seifert AM; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
Schmitz M; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2022 Feb 26; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 26.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Small Step, a Giant Leap: Somatic Hypermutation of a Single Amino Acid Leads to Anti-La Autoreactivity.
Autorzy:
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Puentes-Cala E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Corporación para la Investigación de la Corrosión (CIC), Piedecuesta 681011, Colombia.
Soto JA; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; BIOGEN Research Group, University of Santander, Faculty of Health Sciences, Cúcuta 540001, Colombia.
Kurien BT; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Berndt N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; BIOGEN Research Group, University of Santander, Faculty of Health Sciences, Cúcuta 540001, Colombia.; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.; Tumor Immunology, University Cancer Center (UCC), University Hospital Carl Gustav Carus Dresden, TU Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 03128 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 07; Vol. 22 (21). Date of Electronic Publication: 2021 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Antinuclear/*genetics
Autoantibodies/*genetics
Somatic Hypermutation, Immunoglobulin/*genetics
Amino Acid Sequence ; Amino Acids/genetics ; Amino Acids/metabolism ; Antibodies, Antinuclear/immunology ; Antibodies, Antinuclear/metabolism ; Autoantibodies/chemistry ; Autoantibodies/immunology ; Autoantibodies/metabolism ; Autoimmunity/genetics ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/immunology ; Complementarity Determining Regions/metabolism ; Epitopes/genetics ; Epitopes/immunology ; HeLa Cells ; Humans ; Recombinant Proteins/genetics ; Recombinant Proteins/immunology ; Recombinant Proteins/metabolism ; Sequence Analysis, Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeting Acute Myeloid Leukemia Using the RevCAR Platform: A Programmable, Switchable and Combinatorial Strategy.
Autorzy:
Kittel-Boselli E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Tumor Immunology, University Cancer Center (UCC), University Hospital Carl Gustav Carus Dresden, TU Dresden, 01307 Dresden, Germany.
Soto KEG; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Hoffmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bergmann R; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Department of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.
Koristka S; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Mitwasi N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Berndt N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Altmann H; Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.
Fasslrinner F; Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.
Bornhäuser M; Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; Faculty of Medicine, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, 01307 Dresden, Germany.
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Tumor Immunology, University Cancer Center (UCC), University Hospital Carl Gustav Carus Dresden, TU Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; Faculty of Medicine, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, 01307 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2021 Sep 24; Vol. 13 (19). Date of Electronic Publication: 2021 Sep 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling.
Autorzy:
Berndt N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bippes CC; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
Michalk I; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Puentes-Cala E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Corporación para la Investigación de la Corrosión (CIC), Piedecuesta 681011, Colombia.
Soto JA; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Instituto de Investigación Masira, Facultad de Ciencias Médicas y de la Salud, Universidad de Santander, Cúcuta 540001, Colombia.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bachmann D; Tumor Immunology, University Cancer Center (UCC), University Hospital Carl Gustav Carus Technische Universität Dresden, 01307 Dresden, Germany.
Gross JK; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Gross T; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kurien BT; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Scofield RH; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Farris AD; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
James JA; Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Bergmann R; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Department of Biophysics and Radiobiology, Semmelweis University, 1094 Budapest, Hungary.
Schmitz M; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technische Universität Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 03128 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technische Universität Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 03128 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 08; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
Active Transport, Cell Nucleus*
Autoantigens/*chemistry
Cell Nucleus/*metabolism
Oxygen/*chemistry
Ribonucleoproteins/*chemistry
Antibodies, Monoclonal/chemistry ; Cytoplasm/metabolism ; Epitopes/chemistry ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; Humans ; Lupus Erythematosus, Systemic/immunology ; Lupus Erythematosus, Systemic/metabolism ; Nitric Oxide/metabolism ; Oxidation-Reduction ; Protein Conformation ; Signal Transduction ; Sjogren's Syndrome/immunology ; Sjogren's Syndrome/metabolism ; Ultraviolet Rays ; SS-B Antigen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner.
Autorzy:
Berndt N; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bippes CC; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Michalk I; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bachmann D; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bachmann J; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Puentes-Cala E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Corporación para la Investigación de la Corrosión (CIC), Piedecuesta 681011, Colombia.
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bergmann R; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Department of Biophysics and Radiobiology, Semmelweis University, 1094 Budapest, Hungary.
Gross JK; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Gross T; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kurien BT; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Scofield RH; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Farris AD; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
James JA; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Schmitz M; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.
Fahmy K; Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 25; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidation-Reduction*
Autoantigens/*chemistry
Ribonucleoproteins/*chemistry
Sjogren's Syndrome/*immunology
Antibodies, Antinuclear ; Autoantibodies/immunology ; Autoimmunity ; Cytokines/metabolism ; Disulfides/chemistry ; Epitopes/chemistry ; Humans ; Lupus Erythematosus, Systemic/immunology ; Oxygen/chemistry ; Polymers/chemistry ; Protein Multimerization ; Protein Structure, Secondary ; RNA/chemistry ; RNA-Binding Proteins/immunology ; Recombinant Proteins/chemistry ; Temperature ; SS-B Antigen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation.
Autorzy:
Bachmann MP; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Bartsch T; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Bippes CC; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bachmann D; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Puentes-Cala E; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.; Corporación para la Investigación de la Corrosión (CIC), Piedecuesta, Santander 681011, Colombia.
Bachmann J; University Cancer Center (UCC), Tumor Immunology, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Bartsch H; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Arndt C; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Koristka S; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Loureiro LR; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Kegler A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Laube M; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
Gross JK; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Gross T; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Kurien BT; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Scofield RH; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Farris AD; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
James JA; The Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Schmitz M; National Center for Tumor Diseases (NCT), 01307 Dresden, Germany.; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Institute of Immunology, Medical Faculty Carl Gustav Carus Dresden, Technical University Dresden, 01307 Dresden, Germany.
Feldmann A; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 03128 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 26; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Somatic Hypermutation, Immunoglobulin*
Autoantigens/*immunology
Autoimmunity/*genetics
B-Lymphocytes/*immunology
B-Lymphocytes/*metabolism
Cell Communication/*immunology
Ribonucleoproteins/*immunology
T-Lymphocytes/*immunology
3T3 Cells ; Adoptive Transfer ; Amino Acid Sequence ; Animals ; Antibody Specificity/genetics ; Autoantibodies/chemistry ; Autoantibodies/genetics ; Autoantibodies/immunology ; Autoantigens/chemistry ; Autoimmune Diseases/genetics ; Autoimmune Diseases/immunology ; Autoimmune Diseases/metabolism ; Disease Models, Animal ; Epitope Mapping ; Epitopes/chemistry ; Epitopes/immunology ; Fluorescent Antibody Technique ; Germ Cells/metabolism ; Humans ; Immunization ; Mice ; Mice, Transgenic ; Models, Molecular ; Protein Conformation ; Ribonucleoproteins/chemistry ; T-Lymphocytes/metabolism ; SS-B Antigen
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy.
Autorzy:
Tunger A; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; Institute of Immunology, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .
Sommer U; Institute of Pathology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .
Wehner R; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; Institute of Immunology, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .
Kubasch AS; Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, Leipzig University Hospital, Liebigstraße 22, 04103 Leipzig, Germany.
Grimm MO; Department of Urology, Jena University Hospital, Lessingstraße 1, 07743 Jena, Germany. .
Bachmann MP; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. m.bachmann@hzdr.de.; Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz Center Dresden-Rossendorf, Bautzner Landstraße 400, 01328 Dresden, Germany. m.bachmann@hzdr.de.; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Centre (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. m.bachmann@hzdr.de.; Centre for Regenerative Therapies Dresden, TU Dresden, Fetscherstraße 105, 01307 Dresden, Germany. m.bachmann@hzdr.de.
Platzbecker U; Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, Leipzig University Hospital, Liebigstraße 22, 04103 Leipzig, Germany. .; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Centre (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. .
Bornhäuser M; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Centre (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. .; Centre for Regenerative Therapies Dresden, TU Dresden, Fetscherstraße 105, 01307 Dresden, Germany. .; Department of Medicine I, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .
Baretton G; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; Institute of Pathology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Centre (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. .
Schmitz M; National Center for Tumor Diseases (NCT), University Hospital Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; Institute of Immunology, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstraße 74, 01307 Dresden, Germany. .; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Centre (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. .; Centre for Regenerative Therapies Dresden, TU Dresden, Fetscherstraße 105, 01307 Dresden, Germany. .
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Źródło:
Journal of clinical medicine [J Clin Med] 2019 Sep 25; Vol. 8 (10). Date of Electronic Publication: 2019 Sep 25.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.
Autorzy:
Tunger A; a Institute of Immunology, Medical Faculty , TU Dresden , Dresden , Germany.
Wehner R; a Institute of Immunology, Medical Faculty , TU Dresden , Dresden , Germany.; b National Center for Tumor Diseases , University Hospital Carl Gustav Carus, TU Dresden , Germany.
von Bonin M; b National Center for Tumor Diseases , University Hospital Carl Gustav Carus, TU Dresden , Germany.; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.; d German Cancer Consortium (DKTK) , Dresden , Germany.; e German Cancer Research Center (DKFZ) , Heidelberg , Germany.
Kühn D; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Heidenreich F; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.
Matko S; g Institute of Transfusion Medicine, German Red Cross Blood Donation Service North-East , Dresden , Germany.
Nauerth M; h Institute for Medical Microbiology, Immunology and Hygiene, TU Munich , Munich , Germany.
Rücker-Braun E; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.
Dietz S; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Link CS; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Eugster A; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Odendahl M; g Institute of Transfusion Medicine, German Red Cross Blood Donation Service North-East , Dresden , Germany.
Busch DH; h Institute for Medical Microbiology, Immunology and Hygiene, TU Munich , Munich , Germany.
Tonn T; d German Cancer Consortium (DKTK) , Dresden , Germany.; e German Cancer Research Center (DKFZ) , Heidelberg , Germany.; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.; g Institute of Transfusion Medicine, German Red Cross Blood Donation Service North-East , Dresden , Germany.
Bonifacio E; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Germeroth L; i Juno Therapeutics GmbH , Göttingen , Germany.
Schetelig J; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.
Bachmann MP; b National Center for Tumor Diseases , University Hospital Carl Gustav Carus, TU Dresden , Germany.; d German Cancer Consortium (DKTK) , Dresden , Germany.; e German Cancer Research Center (DKFZ) , Heidelberg , Germany.; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.; j Department of Radioimmunology , Institute of Radiopharmaceutical Cancer Research, Helmholtz Center Dresden-Rossendorf , Dresden , Germany.
Bornhäuser M; b National Center for Tumor Diseases , University Hospital Carl Gustav Carus, TU Dresden , Germany.; c Department of Medicine I , University Hospital of Dresden , Dresden , Germany.; d German Cancer Consortium (DKTK) , Dresden , Germany.; e German Cancer Research Center (DKFZ) , Heidelberg , Germany.; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
Schmitz M; a Institute of Immunology, Medical Faculty , TU Dresden , Dresden , Germany.; b National Center for Tumor Diseases , University Hospital Carl Gustav Carus, TU Dresden , Germany.; d German Cancer Consortium (DKTK) , Dresden , Germany.; e German Cancer Research Center (DKFZ) , Heidelberg , Germany.; f Center for Regenerative Therapies Dresden (CRTD), Medical Faculty, TU Dresden , Dresden , Germany.
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Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2017 May; Vol. 58 (5), pp. 1246-1249. Date of Electronic Publication: 2016 Nov 16.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytotoxicity, Immunologic*
Clonal Evolution/*immunology
Leukemia/*immunology
T-Lymphocytes, Cytotoxic/*immunology
WT1 Proteins/*immunology
Amino Acid Sequence ; Biomarkers ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Coculture Techniques ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Epitopes, T-Lymphocyte/immunology ; Humans ; Immunophenotyping ; Leukemia/metabolism ; Peptides/immunology ; T-Cell Antigen Receptor Specificity ; WT1 Proteins/chemistry
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cryogel-supported stem cell factory for customized sustained release of bispecific antibodies for cancer immunotherapy.
Autorzy:
Aliperta R; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Welzel PB; Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany.
Bergmann R; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Freudenberg U; Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany.
Berndt N; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Feldmann A; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Arndt C; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Koristka S; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.
Stanzione M; Institute of Physiological Chemistry, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Cartellieri M; Cellex Patient Treatment GmbH, Tatzberg 47, 01307 Dresden, Germany.; University Cancer Center (UCC), Technische Universität Dresden, Tumorimmunology, Fetscherstrasse 74, 01307 Dresden, Germany.
Ehninger A; GEMoaB Monoclonals GmbH, Tatzberg 47, 01307 Dresden, Germany.
Ehninger G; Medical Clinic and Policlinic I, University Hospital 'Carl Gustav Carus', Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.; DKTK (German consortium for Translational Cancer Research), Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, 'Carl Gustav Carus' TU Dresden, Dresden, Germany.
Werner C; Leibniz Institute of Polymer Research Dresden (IPF), Hohe Strasse 6, 01069 Dresden, Germany.; DFG-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
Pietzsch J; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.; Department of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, 01069 Dresden, Germany.
Steinbach J; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.; Department of Chemistry and Food Chemistry, School of Science, Technische Universität Dresden, 01069 Dresden, Germany.
Bornhäuser M; Medical Clinic and Policlinic I, University Hospital 'Carl Gustav Carus', Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.; DKTK (German consortium for Translational Cancer Research), Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, 'Carl Gustav Carus' TU Dresden, Dresden, Germany.; DFG-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
Bachmann MP; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, 01328 Dresden, Germany.; DKTK (German consortium for Translational Cancer Research), Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, 'Carl Gustav Carus' TU Dresden, Dresden, Germany.; DFG-Center for Regenerative Therapies Dresden, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 16; Vol. 7, pp. 42855. Date of Electronic Publication: 2017 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific/*metabolism
Cryogels/*administration & dosage
Mesenchymal Stem Cells/*cytology
Neoplasms/*therapy
Animals ; Biocompatible Materials ; Cell Line, Tumor ; Humans ; Immunotherapy/methods ; Mesenchymal Stem Cells/immunology ; Mesenchymal Stem Cells/metabolism ; Mice ; Tissue Scaffolds ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Accumulation of tolerogenic human 6-sulfo LacNAc dendritic cells in renal cell carcinoma is associated with poor prognosis.
Autorzy:
Toma M; Institute of Pathology; University Hospital of Dresden ; Dresden, Germany.
Wehner R; Institute of Immunology; Medical Faculty; TU Dresden ; Dresden, Germany.
Kloß A; Institute of Immunology; Medical Faculty; TU Dresden ; Dresden, Germany.
Hübner L; Institute of Immunology; Medical Faculty; TU Dresden ; Dresden, Germany.
Fodelianaki G; Institute of Immunology; Medical Faculty; TU Dresden ; Dresden, Germany ; Center for Regenerative Therapies Dresden ; Dresden, Germany.
Erdmann K; Department of Urology; University Hospital of Dresden ; Dresden, Germany.
Füssel S; Department of Urology; University Hospital of Dresden ; Dresden, Germany.
Zastrow S; Department of Urology; University Hospital of Dresden ; Dresden, Germany.
Meinhardt M; Institute of Pathology; University Hospital of Dresden ; Dresden, Germany.
Seliger B; Institute for Medical Immunology; Martin Luther University Halle-Wittenberg ; Halle (Saale), Germany.
Brech D; Institute of Molecular Immunology; Helmholtz Center Munich; German Research Center for Environmental Health Munich ; Munich, Germany.
Noessner E; Institute of Molecular Immunology; Helmholtz Center Munich; German Research Center for Environmental Health Munich ; Munich, Germany.
Tonn T; Center for Regenerative Therapies Dresden ; Dresden, Germany ; German Red Cross Blood Service ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany.
Schäkel K; Department of Dermatology; University Hospital of Heidelberg ; Heidelberg, Germany.
Bornhäuser M; Center for Regenerative Therapies Dresden ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany ; Department of Medicine I; University Hospital of Dresden ; Dresden, Germany.
Bachmann MP; Center for Regenerative Therapies Dresden ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany ; Department of Radioimmunology; Institute of Radiopharmaceutical Cancer Research; Helmholtz Center Dresden-Rossendorf ; Dresden, Germany.
Wirth MP; Department of Urology; University Hospital of Dresden ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany.
Baretton G; Institute of Pathology; University Hospital of Dresden ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany.
Schmitz M; Institute of Immunology; Medical Faculty; TU Dresden ; Dresden, Germany ; Center for Regenerative Therapies Dresden ; Dresden, Germany ; German Cancer Consortium (DKTK) ; Dresden, Germany ; German Cancer Research Center (DKFZ) ; Heidelberg, Germany.
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Źródło:
Oncoimmunology [Oncoimmunology] 2015 Mar 02; Vol. 4 (6), pp. e1008342. Date of Electronic Publication: 2015 Mar 02 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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