Autor: "Badder LM" - OpacWWW

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Tytuł:: Efficient Intravenous Tumor Targeting Using the αvβ6 Integrin-Selective Precision Virotherapy Ad5 NULL -A20.
Autorzy:: Davies JA; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Marlow G; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Uusi-Kerttula HK; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Seaton G; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Piggott L; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Badder LM; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.
Clarkson RWE; School of Biosciences, Cardiff University, Cardiff CF24 4HQ, UK.
Chester JD; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.; Velindre Cancer Centre, Cardiff CF14 2TL, UK.
Parker AL; Division of Cancer and Genetics, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 May 08; Vol. 13 (5). Date of Electronic Publication: 2021 May 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Therapy*/methods
Oncolytic Virotherapy*/methods
Adenoviridae/*genetics
Antigens, Neoplasm/*genetics
Genetic Vectors/*genetics
Integrins/*genetics
Neoplasms/*therapy
Oncolytic Viruses/*genetics
Administration, Intravenous ; Animals ; Cell Line, Tumor ; Cell Survival ; Disease Models, Animal ; Genetic Vectors/administration & dosage ; Humans ; Mice ; Neoplasms/etiology ; Transduction, Genetic ; Treatment Outcome ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 2.

Tytuł:: 3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Autorzy:: Badder LM; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
Hollins AJ; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
Herpers B; OcellO B.V., Leiden, The Netherlands.
Yan K; OcellO B.V., Leiden, The Netherlands.
Ewan KB; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
Thomas M; Cellesce Ltd, Cardiff Medicentre, Heath Park, Cardiff, United Kingdom.
Shone JR; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
Badder DA; Cellular Pathology Department, University Hospital for Wales, Cardiff, United Kingdom.
Naven M; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Ashelford KE; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Hargest R; Department of Colorectal Surgery, University Hospital of Wales, Cardiff, United Kingdom.; Division of Cancer and Genetics, CCMRC, Henry Wellcome Building, Cardiff University, Cardiff, United Kingdom.
Clarke AR; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
Esdar C; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
Buchstaller HP; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
Treherne JM; Cellesce Ltd, Cardiff Medicentre, Heath Park, Cardiff, United Kingdom.
Boj S; Hubrecht Organoid Technology, Utrecht, The Netherlands.
Ramezanpour B; Hubrecht Organoid Technology, Utrecht, The Netherlands.
Wienke D; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
Price LS; OcellO B.V., Leiden, The Netherlands.
Shaw PH; Velindre Cancer Centre, Cardiff, Wales, United Kingdom.
Dale TC; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Aug 18; Vol. 15 (8), pp. e0235319. Date of Electronic Publication: 2020 Aug 18 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Colorectal Neoplasms/*drug therapy
Enzyme Inhibitors/*pharmacology
Organoids/*drug effects
Tankyrases/*antagonists & inhibitors
Adult ; Animals ; Antineoplastic Agents/therapeutic use ; Colorectal Neoplasms/pathology ; Enzyme Inhibitors/therapeutic use ; Female ; Humans ; Imaging, Three-Dimensional ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplastic Stem Cells/drug effects ; Organoids/pathology

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