Autor: "Baillie JK" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication.
Autorzy:: Pannhorst K; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany. .
Carlson J; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.; Ceva Animal Health, Greifswald-Insel Riems, Germany.
Hölper JE; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Grey F; The Roslin Institute, University of Edinburgh, Midlothian, UK.
Baillie JK; The Roslin Institute, University of Edinburgh, Midlothian, UK.
Höper D; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Wöhnke E; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Franzke K; Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Karger A; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Fuchs W; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Mettenleiter TC; Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 21; Vol. 13 (1), pp. 10342. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: African Swine Fever Virus*/genetics
African Swine Fever*/genetics
Craniocerebral Trauma*
Animals ; Swine ; DNA Replication ; DNA, Viral ; Virus Replication/genetics ; Histocompatibility Antigens Class II/genetics ; Membrane Proteins ; Major Histocompatibility Complex

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19.
Autorzy:: Siggins MK; National Heart & Lung Institute, Imperial College London, London, UK.
Davies K; Division of Infection and Immunity and UK Dementia Research Institute Cardiff, Cardiff University, Cardiff, UK.
Fellows R; Translational & Clinical Research Institute, Newcastle University, Newcastle, UK.
Thwaites RS; National Heart & Lung Institute, Imperial College London, London, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Semple MG; NIHR Health Protection Research Unit, Institute of Infection, Veterinary, and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Openshaw PJM; National Heart & Lung Institute, Imperial College London, London, UK.
Zelek WM; Division of Infection and Immunity and UK Dementia Research Institute Cardiff, Cardiff University, Cardiff, UK.
Harris CL; Translational & Clinical Research Institute, Newcastle University, Newcastle, UK.
Morgan BP; Division of Infection and Immunity and UK Dementia Research Institute Cardiff, Cardiff University, Cardiff, UK.; Pokaż więcej
Corporate Authors:: ISARIC4C Investigators
Źródło:: Immunology [Immunology] 2023 Mar; Vol. 168 (3), pp. 473-492. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*
Humans ; Complement Activation ; Complement System Proteins/metabolism ; Complement C3b ; Biomarkers ; Disease Progression ; Complement Pathway, Alternative

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study.
Autorzy:: Turtle L; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
Thorpe M; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Drake TM; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Swets M; Department of Infectious Diseases, Leiden University Medical Centre, Leiden University, Leiden, the Netherlands.; The Roslin Institute, Easter Bush campus, University of Edinburgh, Edinburgh, United Kingdom.
Palmieri C; Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Russell CD; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Ho A; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom.
Aston S; Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Wootton DG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
Richter A; Institute of Cancer and Genomic Science, College of Medical and Dental Science, University of Birmingham, Birmingham, United Kingdom.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
de Silva TI; Department of Infection, Immunity and Cardiovascular Disease, Medical School, The University of Sheffield, Sheffield, United Kingdom.
Hardwick HE; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Leeming G; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Law A; The Roslin Institute, Easter Bush campus, University of Edinburgh, Edinburgh, United Kingdom.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Harrison EM; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Baillie JK; The Roslin Institute, Easter Bush campus, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom.; Baillie Gifford Pandemic Science Hub, Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Semple MG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.; Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, United Kingdom.
Docherty AB; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom.; Pokaż więcej
Corporate Authors:: ISARIC4C investigators
Źródło:: PLoS medicine [PLoS Med] 2023 Jan 31; Vol. 20 (1), pp. e1004086. Date of Electronic Publication: 2023 Jan 31 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*
Male ; Humans ; Female ; Middle Aged ; Aged ; SARS-CoV-2 ; Prospective Studies ; Hospital Mortality ; Bayes Theorem ; Immunocompromised Host ; United Kingdom/epidemiology ; World Health Organization

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study.
Autorzy:: Jefferson E; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Cole C; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Mumtaz S; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Cox S; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Giles TC; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Adejumo S; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Urwin E; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Lea D; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Macdonald C; Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Best J; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.; Health Data Research UK, London, United Kingdom.
Masood E; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Milligan G; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Johnston J; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Horban S; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Birced I; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Hall C; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Jackson AS; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Collins C; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Rising S; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Dodsley C; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Hampton J; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Hadfield A; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Santos R; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Tarr S; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Panagi V; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Lavagna J; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.
Jackson T; Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Chuter A; Lay Partnership in Healthcare Research, Lindfield, United Kingdom.
Beggs J; Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom.
Martinez-Queipo M; National Health Service Digital, London, United Kingdom.
Ward H; School of Public Health, Imperial College London, London, United Kingdom.
von Ziegenweidt J; Department of Haemotology, University of Cambridge, Cambridge, United Kingdom.; National Institute for Healthcare Research BioResource, Cambridge University Hospitals NHS Foundation, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Burns F; Centre for Public Health, Belfast Institute of Clinical Science, Queens University Belfast, Belfast, United Kingdom.
Martin J; Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Sebire N; Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom.
Morris C; Public Health Scotland, Edinburgh, United Kingdom.
Bradley D; Centre for Public Health, Institute of Clinical Science, Queen's University Belfast, Belfast, United Kingdom.; Public Health Agency, Belfast, United Kingdom.
Baxter R; EPCC, University of Edinburgh, Edinburgh, United Kingdom.
Ahonen-Bishopp A; BC Platforms, Espoo, Finland.
Smith P; BC Platforms, Espoo, Finland.
Shoemark A; Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
Valdes AM; School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Ollivere B; School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Manisty C; Institute of Cardiovascular Sciences, University of College London, London, United Kingdom.
Eyre D; Big Data Institute, University of Oxford, Oxford, United Kingdom.
Gallant S; Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
Joy G; Barts Heart Centre, London, United Kingdom.
McAuley A; Clinical and Protecting Health Directorate, Public Health Scotland, Glasgow, United Kingdom.
Connell D; School of Medicine, University of Dundee, Dundee, United Kingdom.
Northstone K; Population Health Sciences, Avon Longitudinal Study of Parents and Children, Bristol, United Kingdom.
Jeffery K; Radcliffe Department of Medicine, Oxford University, Oxford, United Kingdom.; Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, United Kingdom.; Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom.; Health Data Science Research Centre, Human Technopole, Milan, Italy.
McMahon A; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, United Kingdom.
Walker M; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, United Kingdom.
Semple MG; Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infections, University of Liverpool, Liverpool, United Kingdom.; Respiratory Department, Alder Hey Children's Hospital, Liverpool, United Kingdom.
Sims JM; University College London, London, United Kingdom.
Lawrence E; BioIndustry Association, London, United Kingdom.
Davies B; School of Public Health, Imperial College London, London, United Kingdom.
Baillie JK; Outbreak Data Analysis Platform, University of Edinburgh, Edinburgh, United Kingdom.
Tang M; NHS England, Worcestershire, United Kingdom.
Leeming G; Civic Data Cooperative, Digital Innovation Facility, University of Liverpool, Liverpool, United Kingdom.
Power L; Public Health England, London, United Kingdom.
Breeze T; Avon Longitudinal Study of Parents and Children, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Murray D; University of Birmingham, Birmingham, United Kingdom.; University Hospital Coventry & Warwickshire NHS Trust, Coventry, United Kingdom.
Orton C; Population Data Science, Swansea University Medical School, Swansea, United Kingdom.
Pierce I; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom.; Institute of Cardiovascular Science, University College London, London, United Kingdom.
Hall I; Nottingham Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Ladhani S; Immunisation and Countermeasures Division, Public Health England Colindale, London, United Kingdom.
Gillson N; UK Health Security Agency, London, United Kingdom.
Whitaker M; School of Public Health, Imperial College London, London, United Kingdom.
Shallcross L; Institute of Health Informatics, UCL, London, United Kingdom.
Seymour D; Health Data Research UK, London, United Kingdom.
Varma S; Health Data Research UK, London, United Kingdom.
Reilly G; Health Data Research UK, London, United Kingdom.
Morris A; Health Data Research UK, London, United Kingdom.
Hopkins S; Public Health England, London, United Kingdom.
Sheikh A; Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Quinlan P; Digital Research Service, University of Nottingham, Nottingham, United Kingdom.; School of Medicine, University of Nottingham, Nottingham, United Kingdom.; Pokaż więcej
Źródło:: Journal of medical Internet research [J Med Internet Res] 2022 Dec 27; Vol. 24 (12), pp. e40035. Date of Electronic Publication: 2022 Dec 27.
Typ publikacji:: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: COVID-19*/epidemiology
Humans ; Pandemics ; United Kingdom/epidemiology

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative.
Autorzy:: Butler-Laporte G; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
Povysil G; Institute for Genomic Medicine, Columbia University, New York city, New York, United States of America.
Kosmicki JA; Regeneron Genetics Center, Tarrytown, New York, United States of America.
Cirulli ET; Helix, San Mateo, California, United States of America.
Drivas T; Division of Human Genetics, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.; Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Furini S; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy.
Saad C; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar.
Schmidt A; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany.
Olszewski P; IMAGENE.ME SA, Bialystok, Poland.
Korotko U; IMAGENE.ME SA, Bialystok, Poland.; Centre for Bioinformatics and Data Analysis, Medical University of Bialystok, Bialystok, Poland.
Quinodoz M; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.; Department of Ophthalmology, University Hospital Basel, Basel, Switzerland.
Çelik E; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University Hospital Basel, Basel, Switzerland.
Kundu K; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom.
Walter K; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom.
Jung J; Department of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, United States of America.; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Stockwell AD; Genentech Inc, South San Francisco, California, United States of America.
Sloofman LG; Seaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Jordan DM; Mount Sinai Clnical Intelligence Center, Charles Bronfman Institute for Personalized Medicine, Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Thompson RC; Icahn Institute of Data Science and Genomics Technology, New York city, New York, United States of America.
Del Valle D; Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Simons N; Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Cheng E; Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Sebra R; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York city,New York, United States of America.
Schadt EE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York city,New York, United States of America.
Kim-Schulze S; Department of Oncological Science, Human Immune Monitoring Center, Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Gnjatic S; Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Merad M; Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Buxbaum JD; Seaver Autism Center for Research and Treatment, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Beckmann ND; Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Charney AW; Mount Sinai Clinical Intelligence Center; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York city, New York, United States of America.
Przychodzen B; Vanda Pharmaceuticals, Washington, District of Columbia, United States of America.
Chang T; Department of Neurology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Pottinger TD; Institute for Genomic Medicine, Columbia University, New York city, New York, United States of America.
Shang N; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York city, New York, United States of America.
Brand F; Institute of Genomic Statistics and Bioinformatics, School of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany.
Fava F; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy.; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Medical Genetics, University of Siena, Siena, Italy.
Mari F; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy.; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Medical Genetics, University of Siena, Siena, Italy.
Chwialkowska K; IMAGENE.ME SA, Bialystok, Poland.; Centre for Bioinformatics and Data Analysis, Medical University of Bialystok, Bialystok, Poland.
Niemira M; Centre for Clinical Research, Medical University of Bialystok, Bialystok, Poland.
Pula S; IMAGENE.ME SA, Bialystok, Poland.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Stuckey A; Genomics England, London, United Kingdom.
Salas A; Unidade de Xenética, Instituto de Ciencias Forenses (INCIFOR), Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigaciones Sanitarias, Hospital Clínico Universitario de Santiago (SERGAS), Santiago de Compostela, Galicia, Spain.; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.
Bello X; Unidade de Xenética, Instituto de Ciencias Forenses (INCIFOR), Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigaciones Sanitarias, Hospital Clínico Universitario de Santiago (SERGAS), Santiago de Compostela, Galicia, Spain.; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.
Pardo-Seco J; Unidade de Xenética, Instituto de Ciencias Forenses (INCIFOR), Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigaciones Sanitarias, Hospital Clínico Universitario de Santiago (SERGAS), Santiago de Compostela, Galicia, Spain.; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.
Gómez-Carballa A; Unidade de Xenética, Instituto de Ciencias Forenses (INCIFOR), Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigaciones Sanitarias, Hospital Clínico Universitario de Santiago (SERGAS), Santiago de Compostela, Galicia, Spain.; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.
Rivero-Calle I; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.; Translational Pediatrics and Infectious Diseases, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Martinón-Torres F; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Santiago de Compostela, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain.; Translational Pediatrics and Infectious Diseases, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Ganna A; Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Massachusetts General Hospital, Harvard Medical School, Boston, Massachussets, United States of America.
Karczewski KJ; Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Veerapen K; Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Bourgey M; Canadian Centre for Computational Genomics, McGill University, Montréal, Québec, Canada.; McGill Genome Center, McGill University, Montréal, Québec, Canada.
Bourque G; Canadian Centre for Computational Genomics, McGill University, Montréal, Québec, Canada.; McGill Genome Center, McGill University, Montréal, Québec, Canada.; Department of Human Genetics, McGill University, Montréal, Québec, Canada.
Eveleigh RJ; Canadian Centre for Computational Genomics, McGill University, Montréal, Québec, Canada.; McGill Genome Center, McGill University, Montréal, Québec, Canada.
Forgetta V; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
Morrison D; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.
Langlais D; McGill Genome Center, McGill University, Montréal, Québec, Canada.; Department of Human Genetics, McGill University, Montréal, Québec, Canada.
Lathrop M; McGill Genome Center, McGill University, Montréal, Québec, Canada.; Department of Human Genetics, McGill University, Montréal, Québec, Canada.
Mooser V; Department of Human Genetics, McGill University, Montréal, Québec, Canada.
Nakanishi T; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Research Fellow, Japan Society for the Promotion of Science, Tokyo, Japan.
Frithiof R; Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Hultström M; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.; Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Integrative Physiology, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Lipcsey M; Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Hedenstierna Laboratory, CIRRUS, Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Marincevic-Zuniga Y; Department of Medical Sciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Nordlund J; Department of Medical Sciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Schiabor Barrett KM; Helix, San Mateo, California, United States of America.
Lee W; Helix, San Mateo, California, United States of America.
Bolze A; Helix, San Mateo, California, United States of America.
White S; Helix, San Mateo, California, United States of America.
Riffle S; Helix, San Mateo, California, United States of America.
Tanudjaja F; Helix, San Mateo, California, United States of America.
Sandoval E; Helix, San Mateo, California, United States of America.
Neveux I; Center for Genomic Medicine, Desert Research Institute, Reno, Nevada United States of America.
Dabe S; Renown Health, Reno, Nevada, United States of America.
Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.; NGS Competence Center Tuebingen, Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
Motameny S; West German Genome Center, site Cologne, University of Cologne, Cologne, Germany.; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
Alaamery M; Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.; Saudi Human Genome Project at King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Massadeh S; Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.; Saudi Human Genome Project at King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Aljawini N; Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.; Saudi Human Genome Project at King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Almutairi MS; Developmental Medicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.; Saudi Human Genome Project at King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Arabi YM; Ministry of the National Guard Health Affairs, King Abdullah International Medical Research Center and King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Alqahtani SA; Liver Transplant Unit, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.; Division of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Al Harthi FS; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Almutairi A; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Alqubaishi F; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Alotaibi S; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Binowayn A; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Alsolm EA; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
El Bardisy H; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Fawzy M; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Cai F; Genentech Inc, South San Francisco, California, United States of America.
Soranzo N; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom.
Butterworth A; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, United Kingdom.
Geschwind DH; Department of Neurology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Arteaga S; Department of Neurology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Stephens A; Department of Pediatrics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Butte MJ; Department of Pediatrics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Boutros PC; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Yamaguchi TN; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Tao S; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Eng S; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Sanders T; Office of Health Informatics and Analytics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Tung PJ; Office of Health Informatics and Analytics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Broudy ME; Office of Health Informatics and Analytics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Pan Y; Office of Health Informatics and Analytics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Gonzalez A; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Chavan N; Office of Health Informatics and Analytics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Johnson R; Department of Computer Science, McGill University, Montréal, Québec, Canada.
Pasaniuc B; Department of Human Genetics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.; Department of Computational Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.; Department of Pathology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, United States of America.
Yaspan B; Genentech Inc, South San Francisco, California, United States of America.
Smieszek S; Vanda Pharmaceuticals, Washington, District of Columbia, United States of America.
Rivolta C; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.; Department of Ophthalmology, University Hospital Basel, Basel, Switzerland.
Bibert S; Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland.
Bochud PY; Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland.
Dabrowski M; MNM Bioscience Inc., Cambridge, Massachusetts, United States of America.
Zawadzki P; MNM Bioscience Inc., Cambridge, Massachusetts, United States of America.; Faculty of Physics, Adam Mickiewicz University, Poznan, Poland.
Sypniewski M; MNM Bioscience Inc., Cambridge, Massachusetts, United States of America.
Kaja E; MNM Bioscience Inc., Cambridge, Massachusetts, United States of America.; Department of Medical Chemistry and Laboratory Medicine, Poznań University of Medical Sciences, Poznań, Poland.
Chariyavilaskul P; Clinical Pharmacokinetics and Pharmacogenomics Research Unit, Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nilaratanakul V; Healthcare-associated Infection Research Group STAR (Special Task Force for Activating Research) and Division of Infectious Diseases, Department of Medicine,Chulalongkorn University, Bangkok, Thailand.
Hirankarn N; Center of Excellence in Immunology and Immune-mediated Diseases, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Shotelersuk V; Center of Excellence for Medical Genomics, Medical Genomics Cluster, and Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Pongpanich M; Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Phokaew C; Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Chetruengchai W; Center of Excellence for Medical Genomics, Medical Genomics Cluster, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Tokunaga K; Genome Medical Science Project, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.
Sugiyama M; Genome Medical Science Project, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan.
Kawai Y; Genome Medical Science Project, National Center for Global Health and Medicine (NCGM), Tokyo, Japan.
Hasegawa T; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
Naito T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Namkoong H; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
Edahiro R; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
Kimura A; Institute of Research, Tokyo Medical and Dental University, Tokyo, Japan.
Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden.
Kanai T; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Fukunaga K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.; Center for Infectious Disease Education and Research (CiDER), Osaka University, Suita, Japan.
Imoto S; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
Miyano S; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
Mangul S; Department of Clinical Pharmacy, School of Pharmacy, University of Southern California, Los Angeles, California, United States of America.
Abedalthagafi MS; Genomics Research Department, Saudi Human Genome Project, King Fahad Medical City and King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
Zeberg H; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Grzymski JJ; Center for Genomic Medicine, Desert Research Institute, Reno, Nevada United States of America.
Washington NL; Helix, San Mateo, California, United States of America.
Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.; NGS Competence Center Tuebingen, Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
Ludwig KU; Institute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany.; West German Genome Center, site Bonn, University of Bonn, Bonn, Germany.
Schulte EC; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Institute of Virology, Technical University Munich/Helmholtz Zentrum München, Munich, Germany.
Riess O; Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.; NGS Competence Center Tuebingen, Institute of Medical Genetics and Applied Genomics, University of Tuebingen, Tuebingen, Germany.
Moniuszko M; Department of Regenerative Medicine and Immune Regulation, Medical University of Bialystok, Bialystok, Poland.; Department of Allergology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland.
Kwasniewski M; IMAGENE.ME SA, Bialystok, Poland.; Centre for Bioinformatics and Data Analysis, Medical University of Bialystok, Bialystok, Poland.
Mbarek H; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar.
Ismail SI; Qatar Genome Program, Qatar Foundation Research, Development and Innovation, Qatar Foundation, Doha, Qatar.
Verma A; Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.; Corporal Michael Crescenz VA Medical Center, Philadelphia, Pennsylvania, United States of America.
Goldstein DB; Institute for Genomic Medicine, Columbia University, New York city, New York, United States of America.; Department of Genetics & Development, Columbia University, New York city, New York, United States of America.
Kiryluk K; Institute for Genomic Medicine, Columbia University, New York city, New York, United States of America.; Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York city, New York, United States of America.
Renieri A; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy.; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.; Medical Genetics, University of Siena, Siena, Italy.
Ferreira MAR; Regeneron Genetics Center, Tarrytown, New York, United States of America.
Richards JB; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.; Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Québec, Canada.; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.; Department of Twin Research, King's College London, London, United Kingdom.; 5 Prime Sciences Inc, Montreal, Quebec, Canada.; Pokaż więcej
Corporate Authors:: COVID-19 Host Genetics Initiative
DeCOI Host Genetics Group
GEN-COVID Multicenter Study (Italy)
Mount Sinai Clinical Intelligence Center
GEN-COVID consortium (Spain)
GenOMICC Consortium
Japan COVID-19 Task Force
Regeneron Genetics Center
Źródło:: PLoS genetics [PLoS Genet] 2022 Nov 03; Vol. 18 (11), pp. e1010367. Date of Electronic Publication: 2022 Nov 03 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Exome*/genetics
COVID-19*/genetics
Humans ; Genome-Wide Association Study ; Genetic Predisposition to Disease ; Toll-Like Receptor 7/genetics ; SARS-CoV-2/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers.
Autorzy:: Dong X; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Penrice-Randal R; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Goldswain H; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Prince T; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Randle N; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Donovan-Banfield I; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, Liverpool, L69 7BE, UK.
Salguero FJ; UK-Health Security Agency, Salisbury, SP4 0JG, UK.
Tree J; UK-Health Security Agency, Salisbury, SP4 0JG, UK.
Vamos E; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Nelson C; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Clark J; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Ryan Y; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Stewart JP; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Semple MG; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, Liverpool, L69 7BE, UK.
Baillie JK; The Roslin Institute, University of Edinburgh, Edinburgh, EH25 9RG, UK.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.
Turtle L; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, Liverpool, L69 7BE, UK.
Matthews DA; University of Bristol, Bristol, BS8 1QU, UK.
Carroll MW; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, Liverpool, L69 7BE, UK.; UK-Health Security Agency, Salisbury, SP4 0JG, UK.
Darby AC; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.
Hiscox JA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, L3 5RF, UK.; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, Liverpool, L69 7BE, UK.; Infectious Diseases Horizontal Technology Centre (ID HTC), A*STAR, 138632, Singapore.; Pokaż więcej
Źródło:: GigaScience [Gigascience] 2022 May 26; Vol. 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: COVID-19*
SARS-CoV-2*/genetics
Animals ; Cell Culture Techniques ; Computational Biology ; Humans ; Mammals/genetics ; Models, Animal ; RNA, Messenger/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission.
Autorzy:: Relph KA; University of Edinburgh Centre for Inflammation Research, Edinburgh, United Kingdom.
Russell CD; University of Edinburgh Centre for Inflammation Research, Edinburgh, United Kingdom.
Fairfield CJ; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Turtle L; National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.; Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
de Silva TI; South Yorkshire Regional Department of Infection and Tropical Medicine, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield, United Kingdom.; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom.
Siggins MK; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Drake TM; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Thwaites RS; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Abrams S; Department of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, United Kingdom.
Moore SC; National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
Hardwick HE; National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.
Oosthuyzen W; Division of Genetics and Genomics, Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Harrison EM; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Docherty AB; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Baillie JK; Division of Genetics and Genomics, Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Medical Research Council Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Semple MG; National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom.; Department of Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, United Kingdom.
Ho A; Medical Research Council-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.; Pokaż więcej
Corporate Authors:: International Severe Acute Respiratory and Emerging Infections Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators
Źródło:: Open forum infectious diseases [Open Forum Infect Dis] 2022 May 01; Vol. 9 (5), pp. ofac179. Date of Electronic Publication: 2022 May 01 (Print Publication: 2022).
Typ publikacji:: Journal Article

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study.
Autorzy:: Millar JE; Division of Functional Genetics and Development, Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh, EH25 9RG, UK.
Neyton L; Division of Functional Genetics and Development, Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh, EH25 9RG, UK.
Seth S; Institute for Adaptive and Neural Computation, School of Informatics, University of Edinburgh, Edinburgh, UK.
Dunning J; National Infection Service, Public Health England, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK.
Merson L; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, ISARIC Global Support Centre, University of Oxford, Oxford, UK.; Infectious Diseases Data Observatory, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Murthy S; BC Children's Hospital, University of British Columbia, Vancouver, Canada.
Russell CD; Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK.
Keating S; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Swets M; Division of Functional Genetics and Development, Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh, EH25 9RG, UK.; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Sudre CH; School of Biomedical and Imaging Sciences, King's College London, London, UK.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Ourselin S; School of Biomedical and Imaging Sciences, King's College London, London, UK.
Steves CJ; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Wolf J; ZOE Global Ltd, London, UK.
Docherty AB; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Harrison EM; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK.
Semple MG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK. .
Baillie JK; Division of Functional Genetics and Development, Roslin Institute, University of Edinburgh, Easter Bush Campus, Midlothian, Edinburgh, EH25 9RG, UK. j.k.baillie@ed.ac.uk.; Pokaż więcej
Corporate Authors:: ISARIC-4C
Źródło:: Scientific reports [Sci Rep] 2022 Apr 27; Vol. 12 (1), pp. 6843. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Confusion ; Cough ; Dyspnea ; Fatigue ; Female ; Fever ; Humans ; Prospective Studies

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: A prenylated dsRNA sensor protects against severe COVID-19.
Autorzy:: Wickenhagen A; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Sugrue E; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Lytras S; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Kuchi S; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Noerenberg M; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Turnbull ML; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Loney C; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Herder V; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Allan J; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Jarmson I; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Cameron-Ruiz N; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Varjak M; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Pinto RM; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Lee JY; Department of Biochemistry, University of Oxford, Oxford, UK.
Iselin L; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.; Department of Biochemistry, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Palmalux N; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Stewart DG; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Swingler S; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Greenwood EJD; Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK.
Crozier TWM; Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK.
Gu Q; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Davies EL; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Clohisey S; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Wang B; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Trindade Maranhão Costa F; Laboratory of Tropical Diseases, Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, Sao Paolo, Brazil.
Freire Santana M; Department of Education and Research, Oncology Control Centre of Amazonas State (FCECON), Manaus, Amazonas, Brazil.
de Lima Ferreira LC; Postgraduate Program in Tropical Medicine, Tropical Medicine Foundation Dr. Heitor Vieira Dourado, Manaus, Amazonas, Brazil.
Murphy L; Edinburgh Clinical Research Facility, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Fawkes A; Edinburgh Clinical Research Facility, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Meynert A; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Grimes G; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
Da Silva Filho JL; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Marti M; Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
Hughes J; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Stanton RJ; Division of Infection & Immunity, Cardiff University, Cardiff, UK.
Wang ECY; Division of Infection & Immunity, Cardiff University, Cardiff, UK.
Ho A; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Davis I; Department of Biochemistry, University of Oxford, Oxford, UK.
Jarrett RF; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Castello A; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Robertson DL; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Semple MG; NIHR Health Protection Research Unit for Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, UK.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare, National Health Service Trust London, London, UK.
Palmarini M; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Lehner PJ; Cambridge Institute of Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Rihn SJ; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.
Wilson SJ; Medical Research Council-University of Glasgow Centre for Virus Research (CVR), Institute of Infection, Inflammation and Immunity, University of Glasgow, Glasgow, UK.; Pokaż więcej
Corporate Authors:: ISARIC4C Investigators
Źródło:: Science (New York, N.Y.) [Science] 2021 Oct 29; Vol. 374 (6567), pp. eabj3624. Date of Electronic Publication: 2021 Oct 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: 2',5'-Oligoadenylate Synthetase/*genetics
2',5'-Oligoadenylate Synthetase/*metabolism
COVID-19/*genetics
COVID-19/*physiopathology
RNA, Double-Stranded/*metabolism
RNA, Viral/*metabolism
SARS-CoV-2/*physiology
5' Untranslated Regions ; A549 Cells ; Animals ; COVID-19/enzymology ; COVID-19/immunology ; Chiroptera/genetics ; Chiroptera/virology ; Coronaviridae/enzymology ; Coronaviridae/genetics ; Coronaviridae/physiology ; Endoribonucleases/metabolism ; Humans ; Interferons/immunology ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Phosphoric Diester Hydrolases/genetics ; Phosphoric Diester Hydrolases/metabolism ; Polymorphism, Single Nucleotide ; Protein Prenylation ; RNA, Double-Stranded/chemistry ; RNA, Double-Stranded/genetics ; RNA, Viral/chemistry ; RNA, Viral/genetics ; Retroelements ; SARS-CoV-2/genetics ; Severity of Illness Index ; Virus Replication

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Characterizing preclinical sub-phenotypic models of acute respiratory distress syndrome: An experimental ovine study.
Autorzy:: Millar JE; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Wildi K; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.; Cardiovascular Research Institute Basel, Basel, Switzerland.
Bartnikowski N; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Australia.
Bouquet M; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
Hyslop K; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
Passmore MR; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
Ki KK; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
See Hoe LE; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
Obonyo NG; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Wellcome Trust Centre for Global Health Research, Imperial College London, UK.
Neyton L; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Pedersen S; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.
Rozencwajg S; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Sorbonne Universités, UPMC Université Paris 06, INSERM, UMRS-1166, ICAN Institute of Cardiometabolism and Nutrition, Medical ICU, Pitié-Salpêtrière University Hospital, Paris, France.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Li Bassi G; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
Suen JY; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.
McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Fraser JF; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.; Faculty of Medicine, University of Queensland, Brisbane, Australia.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2021 Oct; Vol. 9 (19), pp. e15048.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phenotype*
Respiratory Distress Syndrome/*physiopathology
Animals ; Cytokines/blood ; Disease Models, Animal ; Female ; Lipopolysaccharides ; Oleic Acid ; Respiratory Distress Syndrome/blood ; Respiratory Distress Syndrome/chemically induced ; Sheep

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD Pass.
Autorzy:: Hölper JE; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Grey F; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Baillie JK; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh EH25 9RG, UK.
Regan T; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Parkinson NJ; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.
Höper D; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Thamamongood T; Institute of Virology, Medical Center-University of Freiburg, 79110 Freiburg, Germany.; Spemann Graduate School of Biology and Medicine, University of Freiburg, 79110 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79110 Freiburg, Germany.
Schwemmle M; Institute of Virology, Medical Center-University of Freiburg, 79110 Freiburg, Germany.
Pannhorst K; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Wendt L; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Mettenleiter TC; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.
Klupp BG; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald, Insel Riems, Germany.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Aug 09; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genome, Viral*
Host Microbial Interactions*
Mutation*
CRISPR-Cas Systems/*genetics
Herpesvirus 1, Suid/*genetics
Transferases (Other Substituted Phosphate Groups)/*genetics
Animals ; Cell Line ; Gene Editing ; Kidney/cytology ; Kidney/virology ; Swine ; Transferases (Other Substituted Phosphate Groups)/metabolism ; Virus Replication

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Obesity, chronic disease, age, and in-hospital mortality in patients with covid-19: analysis of ISARIC clinical characterisation protocol UK cohort.
Autorzy:: Yates T; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK. .; National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC), Leicester General Hospital, Leicester, LE5 4PW, UK. .
Zaccardi F; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester, UK.
Islam N; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
Razieh C; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC), Leicester General Hospital, Leicester, LE5 4PW, UK.
Gillies CL; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester, UK.
Lawson CA; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.
Chudasama Y; Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester, UK.
Rowlands A; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC), Leicester General Hospital, Leicester, LE5 4PW, UK.
Davies MJ; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC), Leicester General Hospital, Leicester, LE5 4PW, UK.
Docherty AB; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, UK.
Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.
Semple MG; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections and Institute of Translational Medicine, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.; Respiratory Medicine, Alder Hey Children's Hospital, Institute in The Park, University of Liverpool, Alder Hey Children's Hospital, L12 2AP, Liverpool, UK.
Khunti K; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, LE5 4PW, UK.; Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester, UK.; NIHR Applied Research Collaboration - East Midlands (ARC-EM), Leicester General Hospital, Leicester, UK.; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2021 Jul 31; Vol. 21 (1), pp. 717. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji:: Journal Article
MeSH Terms:: COVID-19*
Aged ; Chronic Disease ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Obesity/complications ; Obesity/epidemiology ; SARS-CoV-2 ; United Kingdom/epidemiology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Global infectious disease research collaborations in crises: building capacity and inclusivity through cooperation.
Autorzy:: Fanning JP; Faculty of Medicine, University of Queensland, Brisbane, Australia. .; Nuffield Department of Population Health, University of Oxford, Oxford, UK. .; Critical Care Research Group, The Prince Charles Hospital, 627 Rode Road, Chermside, 4032, Level 3, Clinical Sciences Building, Chermside, Queensland, Australia. .
Murthy S; Department of Paediatrics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Obonyo NG; Faculty of Medicine, University of Queensland, Brisbane, Australia.; Critical Care Research Group, The Prince Charles Hospital, 627 Rode Road, Chermside, 4032, Level 3, Clinical Sciences Building, Chermside, Queensland, Australia.; Initiative to Develop African Research Leaders (IDeAL)/KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.; Wellcome Trust Centre for Global Health Research, Imperial College London, London, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK.; Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.
Webb S; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.
Dalton HJ; Inova Fairfax Medical Centre, Heart and Vascular Institute, Falls Church, VA, USA.
Fraser JF; Faculty of Medicine, University of Queensland, Brisbane, Australia.; Critical Care Research Group, The Prince Charles Hospital, 627 Rode Road, Chermside, 4032, Level 3, Clinical Sciences Building, Chermside, Queensland, Australia.; Pokaż więcej
Źródło:: Globalization and health [Global Health] 2021 Jul 26; Vol. 17 (1), pp. 84. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji:: Letter; Research Support, Non-U.S. Gov't
MeSH Terms:: Capacity Building*
Global Health*
International Cooperation*
Biomedical Research/*organization & administration
COVID-19/*prevention & control
COVID-19/epidemiology ; Humans

Raport

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Histological Evidence of Pulmonary Microthrombosis and Vasculitis in Life-Threatening Respiratory Virus Diseases.
Autorzy:: Dolby HW; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Potey P; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Wilder-Smith AB; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Clohisey S; Roslin Institute, Division of Genetics and Genomics, University of Edinburgh, Edinburgh, United Kingdom.
Millar JE; Roslin Institute, Division of Genetics and Genomics, University of Edinburgh, Edinburgh, United Kingdom.
Baillie JK; Roslin Institute, Division of Genetics and Genomics, University of Edinburgh, Edinburgh, United Kingdom.
Dorward DA; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Lucas CD; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.
Russell CD; University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.; Roslin Institute, Division of Genetics and Genomics, University of Edinburgh, Edinburgh, United Kingdom.; Pokaż więcej
Źródło:: Open forum infectious diseases [Open Forum Infect Dis] 2020 Dec 28; Vol. 8 (2), pp. ofaa640. Date of Electronic Publication: 2020 Dec 28 (Print Publication: 2021).
Typ publikacji:: Journal Article

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19.
Autorzy:: Parkinson N; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Rodgers N; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Head Fourman M; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Wang B; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Zechner M; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Swets MC; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Millar JE; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Law A; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.
Russell CD; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK.; University of Edinburgh Centre for Inflammation Research, The Queen's Medical Research Institute, Edinburgh, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK. j.k.baillie@ed.ac.uk.
Clohisey S; Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Dec 18; Vol. 10 (1), pp. 22303. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji:: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:: COVID-19/*epidemiology
COVID-19/*genetics
Algorithms ; CD3 Complex/genetics ; CD4 Antigens/genetics ; Chemokine CXCL10/genetics ; Computational Biology ; Cyclophilin A/genetics ; Cyclosporine/pharmacology ; Databases, Genetic ; Genome-Wide Association Study ; Genomics ; Humans ; Immune System ; Immunogenetics ; Inflammation ; Interleukin-1alpha/genetics ; Microtubule-Associated Proteins/genetics ; Proteomics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism.
Autorzy:: Moore SC; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Penrice-Randal R; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Alruwaili M; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Randle N; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Armstrong S; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Hartley C; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Haldenby S; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Dong X; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Alrezaihi A; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Almsaud M; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Bentley E; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Clark J; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
García-Dorival I; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Gilmore P; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Han X; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Jones B; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Luu L; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Sharma P; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Shawli G; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.
Sun Y; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Zhao Q; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Pullan ST; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.
Carter DP; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.
Bewley K; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.
Dunning J; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.
Zhou EM; College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
Solomon T; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.
Beadsworth M; Tropical & Infectious Disease Unit, Liverpool University Hospitals NHS Foundation Trust (a member of Liverpool Health Partners), Liverpool L7 8XP, UK.
Cruise J; Tropical & Infectious Disease Unit, Liverpool University Hospitals NHS Foundation Trust (a member of Liverpool Health Partners), Liverpool L7 8XP, UK.
Crook DW; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
Matthews DA; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK.
Mahmood Z; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Laboratory Department, Directorate of Veterinary in Sulaimany, Rizgari 402, Sulaimani, Kurdistan Region 46001, Iraq.
Aljabr W; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Research Center, King Fahad Medical City, Riyadh 11525, Saudi Arabia.
Druce J; The Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia.
Vipond R; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.
Ng L; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.; Infectious Diseases Horizontal Technology Centre (ID HTC), A*STAR, Singapore 138648, Singapore.
Renia L; Infectious Diseases Horizontal Technology Centre (ID HTC), A*STAR, Singapore 138648, Singapore.
Openshaw PJM; Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.
Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, UK.
Carroll MW; National Infection Service, Public Health England, Salisbury SP4 0JG, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
Stewart J; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.
Darby A; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.
Semple M; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.
Turtle L; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.
Hiscox JA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L3 5RF, UK.; Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool L69 7BE, UK.; Liverpool Health Partners, Liverpool L3 5TF, UK.; Infectious Diseases Horizontal Technology Centre (ID HTC), A*STAR, Singapore 138648, Singapore.; Pokaż więcej
Źródło:: Viruses [Viruses] 2020 Oct 14; Vol. 12 (10). Date of Electronic Publication: 2020 Oct 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Betacoronavirus/*genetics
Coronavirus Infections/*virology
Pneumonia, Viral/*virology
Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; DNA, Complementary/analysis ; DNA, Complementary/genetics ; DNA, Viral/analysis ; DNA, Viral/genetics ; Genome, Viral ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Molecular Epidemiology ; Multiplex Polymerase Chain Reaction ; Pandemics ; Pneumonia, Viral/diagnosis ; RNA, Viral/analysis ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2 ; Sequence Analysis

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Letter to the Editor: Response to Luke Fletcher and Philip Peyton regarding "Predictive validity of a novel non-invasive estimation of effective shunt fraction in critically ill patients".
Autorzy:: Chang EM; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Bretherick A; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.; MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, EH4 2XU, UK.
Drummond GB; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Baillie JK; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK. j.k.baillie@ed.ac.uk.; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK. j.k.baillie@ed.ac.uk.; Pokaż więcej
Źródło:: Intensive care medicine experimental [Intensive Care Med Exp] 2020 Oct 01; Vol. 8 (1), pp. 57. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji:: Letter

Opinia redakcyjna

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Correction to: Predictive validity of a novel non-invasive estimation of effective shunt fraction in critically ill patients.
Autorzy:: Chang EM; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Bretherick A; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.; MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, EH4 2XU, UK.
Drummond GB; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Baillie JK; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK. j.k.baillie@ed.ac.uk.; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK. j.k.baillie@ed.ac.uk.; Pokaż więcej
Źródło:: Intensive care medicine experimental [Intensive Care Med Exp] 2020 Jul 10; Vol. 8 (1), pp. 30. Date of Electronic Publication: 2020 Jul 10.
Typ publikacji:: Published Erratum

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.
Autorzy:: Bretherick AD; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Canela-Xandri O; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Clark DW; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Rawlik K; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Boutin TS; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Zeng Y; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.; Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Amador C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Tenesa A; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Ponting CP; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Baillie JK; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Haley C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2020 Jul 06; Vol. 16 (7), pp. e1008785. Date of Electronic Publication: 2020 Jul 06 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mendelian Randomization Analysis*
Cardiovascular Diseases/*genetics
Proteome/*genetics
Schizophrenia/*genetics
Antigens, Differentiation/genetics ; Cardiovascular Diseases/pathology ; Fatty Acid-Binding Proteins/genetics ; Female ; Fibroblast Growth Factor 5/genetics ; Genetic Association Studies/methods ; Humans ; Lipoprotein Lipase/genetics ; Lymphotoxin-alpha/genetics ; Male ; Quantitative Trait Loci ; Receptors, Immunologic/genetics ; Receptors, Interleukin-6/genetics ; Schizophrenia/pathology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Predictive validity of a novel non-invasive estimation of effective shunt fraction in critically ill patients.
Autorzy:: Chang EM; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Bretherick A; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.; MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, EH4 2XU, UK.
Drummond GB; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK.
Baillie JK; Anaesthesia, Critical Care and Pain Medicine, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK. j.k.baillie@ed.ac.uk.; The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, EH25 9RG, UK. j.k.baillie@ed.ac.uk.; Pokaż więcej
Źródło:: Intensive care medicine experimental [Intensive Care Med Exp] 2019 Aug 20; Vol. 7 (1), pp. 49. Date of Electronic Publication: 2019 Aug 20.
Typ publikacji:: Journal Article

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Baillie JK"" wg kryterium: Autor

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język