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Tytuł :
Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension.
Autorzy :
Bannister JP
Bulley S
Narayanan D
Thomas-Gatewood C
Luzny P
Pachuau J
Jaggar JH
Bannister, John P
Bulley, Simon
Narayanan, Damodaran
Thomas-Gatewood, Candice
Luzny, Patrik
Pachuau, Judith
Jaggar, Jonathan H
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Źródło :
Hypertension (0194911X); Oct2012, Vol. 60 Issue 4, p1006-1015, 10p
Czasopismo naukowe
Tytuł :
Rab25 influences functional Cav1.2 channel surface expression in arterial smooth muscle cells.
Autorzy :
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bulley S; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Kidd MW; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee .
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2016 Jun 01; Vol. 310 (11), pp. C885-93. Date of Electronic Publication: 2016 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium Channels, L-Type/*metabolism
Muscle, Smooth, Vascular/*enzymology
Myocytes, Smooth Muscle/*enzymology
rab GTP-Binding Proteins/*metabolism
Animals ; Cells, Cultured ; Cerebral Arteries/enzymology ; Lysosomes/metabolism ; Male ; Membrane Potentials ; Proteasome Endopeptidase Complex/metabolism ; Protein Transport ; Proteolysis ; RNA Interference ; Rats, Sprague-Dawley ; Signal Transduction ; Transfection ; Vasoconstriction ; rab GTP-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction.
Autorzy :
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bulley S; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Kuruvilla KP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Narayanan D; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee .
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2015 Sep 15; Vol. 309 (6), pp. C392-402. Date of Electronic Publication: 2015 Jul 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*pharmacology
Cell Membrane/*metabolism
Cerebral Arteries/*metabolism
Large-Conductance Calcium-Activated Potassium Channels/*metabolism
Muscle Cells/*metabolism
Proteolysis/*drug effects
Vasoconstriction/*drug effects
Animals ; Cerebral Arteries/drug effects ; Endosomes/drug effects ; Endosomes/metabolism ; Male ; Membrane Potentials/drug effects ; Muscle Cells/drug effects ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Rats ; Rats, Sprague-Dawley ; Vasoconstrictor Agents/pharmacology
Czasopismo naukowe
Tytuł :
Intravascular pressure enhances the abundance of functional Kv1.5 channels at the surface of arterial smooth muscle cells.
Autorzy :
Kidd MW; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Leo MD; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Jaggar JH; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA. .
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Źródło :
Science signaling [Sci Signal] 2015 Aug 18; Vol. 8 (390), pp. ra83. Date of Electronic Publication: 2015 Aug 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Membrane/*physiology
Kv1.5 Potassium Channel/*physiology
Mesenteric Arteries/*physiology
Myocytes, Smooth Muscle/*physiology
Vasoconstriction/*physiology
Animals ; Blotting, Western ; Cells, Cultured ; HEK293 Cells ; Humans ; In Vitro Techniques ; Kv1.5 Potassium Channel/genetics ; Kv1.5 Potassium Channel/metabolism ; Male ; Membrane Potentials/physiology ; Mesenteric Arteries/cytology ; Mesenteric Arteries/metabolism ; Myocytes, Smooth Muscle/metabolism ; Patch-Clamp Techniques ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
LRRC26 is a functional BK channel auxiliary γ subunit in arterial smooth muscle cells.
Autorzy :
Evanson KW; From the Department of Physiology, University of Tennessee Health Science Center, Memphis.
Bannister JP; From the Department of Physiology, University of Tennessee Health Science Center, Memphis.
Leo MD; From the Department of Physiology, University of Tennessee Health Science Center, Memphis.
Jaggar JH; From the Department of Physiology, University of Tennessee Health Science Center, Memphis. .
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Źródło :
Circulation research [Circ Res] 2014 Aug 01; Vol. 115 (4), pp. 423-31. Date of Electronic Publication: 2014 Jun 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Large-Conductance Calcium-Activated Potassium Channels/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Neoplasm Proteins/*metabolism
Animals ; Blotting, Western ; Calcium Signaling ; Cerebral Arteries/metabolism ; Gene Expression Regulation ; Immunoprecipitation ; Large-Conductance Calcium-Activated Potassium Channels/genetics ; Male ; Membrane Potentials ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/drug effects ; Neoplasm Proteins/genetics ; Protein Subunits ; RNA Interference ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction ; Tissue Culture Techniques ; Transfection ; Vasoconstriction ; Vasoconstrictor Agents/pharmacology ; Vasodilation ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł :
Dynamic regulation of β1 subunit trafficking controls vascular contractility.
Autorzy :
Leo MD; Departments of Physiology and Neurosurgery, University of Tennessee Health Science Center, Memphis, TN 38163.
Bannister JP
Narayanan D
Nair A
Grubbs JE
Gabrick KS
Boop FA
Jaggar JH
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Feb 11; Vol. 111 (6), pp. 2361-6. Date of Electronic Publication: 2014 Jan 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Vessels/*physiology
Potassium Channels, Calcium-Activated/*physiology
Animals ; Fluorescence Resonance Energy Transfer ; Ion Transport ; Male ; Patch-Clamp Techniques ; Potassium Channels, Calcium-Activated/chemistry ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator.
Autorzy :
Bannister JP; Department of Physiology, University of Tennessee Health Science Centre, 894 Union Avenue, Suite 426, Memphis, TN 38163, USA.
Leo MD
Narayanan D
Jangsangthong W
Nair A
Evanson KW
Pachuau J
Gabrick KS
Boop FA
Jaggar JH
Pokaż więcej
Źródło :
The Journal of physiology [J Physiol] 2013 Jun 15; Vol. 591 (12), pp. 2987-98. Date of Electronic Publication: 2013 Apr 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Vasodilation*
Calcium Channels, L-Type/*metabolism
Muscle, Smooth, Vascular/*metabolism
Action Potentials ; Active Transport, Cell Nucleus ; Adolescent ; Animals ; Calcium Channels, L-Type/chemistry ; Calcium Channels, L-Type/genetics ; Cell Nucleus/metabolism ; Cerebral Arteries/cytology ; Cerebral Arteries/physiology ; Humans ; Male ; Muscle, Smooth, Vascular/physiology ; Mutation ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/physiology ; Nuclear Localization Signals ; Protein Structure, Tertiary ; Rats ; Rats, Sprague-Dawley ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Role of hydrophobic and ionic forces in the movement of S4 of the Shaker potassium channel.
Autorzy :
Elliott DJ; Multidisciplinary Cardiovascular Research Centre, Institute of Membrane and Systems Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.
Neale EJ
Munsey TS
Bannister JP
Sivaprasadarao A
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Źródło :
Molecular membrane biology [Mol Membr Biol] 2012 Dec; Vol. 29 (8), pp. 321-32. Date of Electronic Publication: 2012 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hydrophobic and Hydrophilic Interactions*/drug effects
Shaker Superfamily of Potassium Channels/*chemistry
Shaker Superfamily of Potassium Channels/*metabolism
Amino Acid Sequence ; Animals ; Cadmium/pharmacology ; Cysteine/genetics ; Ion Channel Gating/drug effects ; Ions ; Kinetics ; Molecular Sequence Data ; Mutant Proteins/metabolism ; Mutation/genetics ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Protein Subunits/chemistry ; Protein Transport/drug effects ; Xenopus
Czasopismo naukowe
Tytuł :
TMEM16A/ANO1 channels contribute to the myogenic response in cerebral arteries.
Autorzy :
Bulley S; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Neeb ZP
Burris SK
Bannister JP
Thomas-Gatewood CM
Jangsangthong W
Jaggar JH
Pokaż więcej
Źródło :
Circulation research [Circ Res] 2012 Sep 28; Vol. 111 (8), pp. 1027-36. Date of Electronic Publication: 2012 Aug 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blood Pressure/*physiology
Calcium Signaling/*physiology
Cerebral Arteries/*physiology
Chloride Channels/*physiology
Myocytes, Smooth Muscle/*physiology
Animals ; Anoctamin-1 ; Calcium Channel Blockers/pharmacology ; Calcium Signaling/drug effects ; Cerebral Arteries/cytology ; Cerebrovascular Circulation/physiology ; Chloride Channels/genetics ; Chlorides/metabolism ; HEK293 Cells ; Humans ; Imidazoles/pharmacology ; Male ; Myocytes, Smooth Muscle/cytology ; Nimodipine/pharmacology ; Patch-Clamp Techniques ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley ; Thapsigargin/pharmacology ; Vasoconstriction/physiology
Czasopismo naukowe
Tytuł :
TMEM16A channels generate Ca²⁺-activated Cl⁻ currents in cerebral artery smooth muscle cells.
Autorzy :
Thomas-Gatewood C; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Neeb ZP
Bulley S
Adebiyi A
Bannister JP
Leo MD
Jaggar JH
Pokaż więcej
Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2011 Nov; Vol. 301 (5), pp. H1819-27. Date of Electronic Publication: 2011 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium/*metabolism
Chloride Channels/*metabolism
Chlorides/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Animals ; Anoctamin-1 ; Blotting, Western ; Cell Membrane/metabolism ; Chloride Channels/genetics ; Fluorescent Antibody Technique ; HEK293 Cells ; Humans ; Male ; Membrane Potentials ; Microscopy, Confocal ; Middle Cerebral Artery/metabolism ; Patch-Clamp Techniques ; Polymerase Chain Reaction ; RNA Interference ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Transfection
Czasopismo naukowe
Tytuł :
Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells.
Autorzy :
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Thomas-Gatewood CM
Neeb ZP
Adebiyi A
Cheng X
Jaggar JH
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2011 Apr 29; Vol. 286 (17), pp. 15058-66. Date of Electronic Publication: 2011 Feb 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Vasoconstriction*
Calcium Channels, L-Type/*genetics
Cerebral Arteries/*physiology
Gene Expression Regulation/*physiology
Myocytes, Smooth Muscle/*metabolism
Animals ; Calcium/metabolism ; Calcium Channels, L-Type/physiology ; Cell Membrane/metabolism ; Cerebral Arteries/cytology ; Chickens ; Guinea Pigs ; Humans ; Muscle, Smooth, Vascular/cytology ; Protein Isoforms/physiology ; Rats
Czasopismo naukowe
Tytuł :
Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility.
Autorzy :
Adebiyi A; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38139, USA.
Zhao G
Narayanan D
Thomas-Gatewood CM
Bannister JP
Jaggar JH
Pokaż więcej
Źródło :
Circulation research [Circ Res] 2010 May 28; Vol. 106 (10), pp. 1603-12. Date of Electronic Publication: 2010 Apr 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Arteries/*physiology
Inositol 1,4,5-Trisphosphate Receptors/*physiology
Muscle Cells/*physiology
Muscle, Smooth, Vascular/*physiology
TRPC Cation Channels/*physiology
Vasoconstriction/*physiology
Animals ; Cell Line ; Cerebral Arteries/cytology ; Gene Silencing ; Homeostasis ; Humans ; Kidney ; Microscopy, Confocal ; Muscle Cells/cytology ; Rats ; Rats, Sprague-Dawley ; TRPC Cation Channels/deficiency ; TRPC Cation Channels/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Smooth muscle cell alpha2delta-1 subunits are essential for vasoregulation by CaV1.2 channels.
Autorzy :
Bannister JP; Department of Physiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Adebiyi A
Zhao G
Narayanan D
Thomas CM
Feng JY
Jaggar JH
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Źródło :
Circulation research [Circ Res] 2009 Nov 06; Vol. 105 (10), pp. 948-55. Date of Electronic Publication: 2009 Oct 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels, L-Type/*metabolism
Cerebral Arteries/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Vasoconstriction/*physiology
Vasodilation/*physiology
Animals ; Anticonvulsants/pharmacology ; Calcium/metabolism ; Cells, Cultured ; Cerebral Arteries/cytology ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/physiology ; Gene Knockdown Techniques ; Male ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/cytology ; Pregabalin ; Protein Isoforms/metabolism ; Protein Subunits/metabolism ; Rats ; Rats, Sprague-Dawley ; Vasoconstriction/drug effects ; Vasodilation/drug effects ; gamma-Aminobutyric Acid/analogs & derivatives ; gamma-Aminobutyric Acid/pharmacology
Czasopismo naukowe
Tytuł :
A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits.
Autorzy :
Cheng X; Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Liu J
Asuncion-Chin M
Blaskova E
Bannister JP
Dopico AM
Jaggar JH
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2007 Oct 05; Vol. 282 (40), pp. 29211-21. Date of Electronic Publication: 2007 Aug 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Arteries/*metabolism
Calcium Channels, L-Type/*chemistry
Animals ; Base Sequence ; COS Cells ; Calcium Channels, L-Type/physiology ; Chlorocebus aethiops ; Electrophysiology/methods ; Humans ; Molecular Sequence Data ; Muscle Cells/metabolism ; Myocardium/metabolism ; Protein Structure, Tertiary ; Rats ; Rats, Sprague-Dawley ; Sequence Homology, Nucleic Acid ; Signal Transduction
Czasopismo naukowe
Tytuł :
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes.
Autorzy :
Waters MF; Division of Neurology and Rose Moss Laboratory for Parkinson's and Neurodegenerative Diseases, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048 USA.
Minassian NA
Stevanin G
Figueroa KP
Bannister JP
Nolte D
Mock AF
Evidente VG
Fee DB
Müller U
Dürr A
Brice A
Papazian DM
Pulst SM
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Źródło :
Nature genetics [Nat Genet] 2006 Apr; Vol. 38 (4), pp. 447-51. Date of Electronic Publication: 2006 Feb 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ion Channel Gating*
Mutation*
Mutation, Missense*
Cerebellar Ataxia/*genetics
Shaw Potassium Channels/*genetics
Amino Acid Sequence ; Animals ; Humans ; Molecular Sequence Data ; Phenotype ; Shaw Potassium Channels/chemistry ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor.
Autorzy :
Bannister JP; Department of Physiology, Geffen School of Medicine, University of California, Los Angeles, CA 90095-1751, USA.
Chanda B
Bezanilla F
Papazian DM
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2005 Dec 20; Vol. 102 (51), pp. 18718-23. Date of Electronic Publication: 2005 Dec 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ether-A-Go-Go Potassium Channels/*chemistry
Ether-A-Go-Go Potassium Channels/*metabolism
Ion Channel Gating/*drug effects
Magnesium/*pharmacology
Animals ; Cations, Divalent/pharmacology ; Electrophysiology ; Ether-A-Go-Go Potassium Channels/genetics ; Fluorescence ; Kinetics ; Lysine/genetics ; Lysine/metabolism ; Oocytes/metabolism ; Patch-Clamp Techniques ; Protein Conformation ; Spectrometry, Fluorescence ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel.
Autorzy :
Silverman WR; Department of Physiology and Molecular Biology Institute, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095-1751, USA.
Bannister JP
Papazian DM
Pokaż więcej
Źródło :
Biophysical journal [Biophys J] 2004 Nov; Vol. 87 (5), pp. 3110-21. Date of Electronic Publication: 2004 Sep 03.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Ion Channel Gating/*physiology
Membrane Potentials/*physiology
Metals/*pharmacology
Oocytes/*physiology
Potassium Channels/*physiology
Amino Acid Substitution ; Animals ; Binding Sites ; Cells, Cultured ; Dose-Response Relationship, Drug ; Ether-A-Go-Go Potassium Channels ; Ion Channel Gating/drug effects ; Ions ; Magnesium/pharmacology ; Manganese/pharmacology ; Membrane Potentials/drug effects ; Mutagenesis, Site-Directed ; Nickel/pharmacology ; Potassium Channels/drug effects ; Protein Binding ; Protein Structure, Tertiary/drug effects ; Recombinant Proteins/metabolism ; Structure-Activity Relationship ; Xenopus
Czasopismo naukowe
Tytuł :
Atomic proximity between S4 segment and pore domain in Shaker potassium channels.
Autorzy :
Lainé M; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA.
Lin MC
Bannister JP
Silverman WR
Mock AF
Roux B
Papazian DM
Pokaż więcej
Źródło :
Neuron [Neuron] 2003 Jul 31; Vol. 39 (3), pp. 467-81.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Models, Molecular*
Potassium Channels/*chemistry
Potassium Channels/*physiology
Animals ; Female ; Membrane Potentials/physiology ; Mutation ; Oocytes ; Shaker Superfamily of Potassium Channels ; Xenopus
Czasopismo naukowe
Tytuł :
The effects of oxidizing and cysteine-reactive reagents on the inward rectifier potassium channels Kir2.3 and Kir1.1.
Autorzy :
Bannister JP; School of Biomedical Sciences, University of Leeds, UK.
Young BA
Main MJ
Sivaprasadarao A
Wray D
Pokaż więcej
Źródło :
Pflugers Archiv : European journal of physiology [Pflugers Arch] 1999 Nov; Vol. 438 (6), pp. 868-78.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Potassium Channels, Inwardly Rectifying*
4-Chloromercuribenzenesulfonate/*pharmacology
Hydrogen Peroxide/*pharmacology
Oxidants/*pharmacology
Potassium Channels/*drug effects
Thimerosal/*pharmacology
Animals ; Cysteine/metabolism ; Cysteine/physiology ; Extracellular Space/metabolism ; Female ; Mutation/physiology ; Oocytes ; Potassium Channel Blockers ; Potassium Channels/genetics ; Xenopus
Czasopismo naukowe
Tytuł :
Conserved extracellular cysteine residues in the inwardly rectifying potassium channel Kir2.3 are required for function but not expression in the membrane.
Autorzy :
Bannister JP; School of Biomedical Sciences, University of Leeds, UK.
Young BA
Sivaprasadarao A
Wray D
Pokaż więcej
Źródło :
FEBS letters [FEBS Lett] 1999 Sep 24; Vol. 458 (3), pp. 393-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Conserved Sequence*
Potassium Channels, Inwardly Rectifying*
Cysteine/*genetics
Potassium Channels/*genetics
Animals ; Fluorescent Antibody Technique ; Membrane Proteins/chemistry ; Mice ; Microinjections ; Mutation ; Oligopeptides ; Oocytes ; Patch-Clamp Techniques ; Peptides/genetics ; Potassium Channels/metabolism ; Protein Biosynthesis ; RNA, Messenger ; Reticulocytes ; Xenopus
Czasopismo naukowe

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